Home Sulfos 1-Propanesulfonic acid,3-(acetylamino)-

1-Propanesulfonic acid,3-(acetylamino)-

CAS No.:
77337-76-9
Catalog Number:
AG005NPB
Molecular Formula:
C5H11NO4S
Molecular Weight:
181.2101
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Purity
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Product Description
Catalog Number:
AG005NPB
Chemical Name:
1-Propanesulfonic acid,3-(acetylamino)-
CAS Number:
77337-76-9
Molecular Formula:
C5H11NO4S
Molecular Weight:
181.2101
MDL Number:
MFCD00867423
IUPAC Name:
3-acetamidopropane-1-sulfonic acid
InChI:
InChI=1S/C5H11NO4S/c1-5(7)6-3-2-4-11(8,9)10/h2-4H2,1H3,(H,6,7)(H,8,9,10)
InChI Key:
AFCGFAGUEYAMAO-UHFFFAOYSA-N
SMILES:
CC(=O)NCCCS(=O)(=O)O
EC Number:
278-667-4
UNII:
N4K14YGM3J
Properties
Complexity:
215  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
181.041g/mol
Formal Charge:
0
Heavy Atom Count:
11  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
181.206g/mol
Monoisotopic Mass:
181.041g/mol
Rotatable Bond Count:
4  
Topological Polar Surface Area:
91.8A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-1.2  
Literature
Title Journal
Acamprosate in a mouse model of fragile X syndrome: modulation of spontaneous cortical activity, ERK1/2 activation, locomotor behavior, and anxiety. Journal of neurodevelopmental disorders 20170101
Impact of acamprosate on behavior and brain-derived neurotrophic factor: an open-label study in youth with fragile X syndrome. Psychopharmacology 20130701
New pharmacological treatment strategies for relapse prevention. Current topics in behavioral neurosciences 20130101
Cigarette smoking predicts differential benefit from naltrexone for alcohol dependence. Biological psychiatry 20121115
Cocaine reverses the naltrexone-induced reduction in operant ethanol self-administration: the effects on immediate-early gene expression in the rat prefrontal cortex. Neuropharmacology 20121101
Involvement of mGlu5 and NMDA receptors in the antidepressant-like effect of acamprosate in the tail suspension test. Progress in neuro-psychopharmacology & biological psychiatry 20121001
The impact of acamprosate on cue reactivity in alcohol dependent individuals: a functional magnetic resonance imaging study. Journal of clinical psychopharmacology 20121001
The glycine reuptake inhibitor Org24598 and acamprosate reduce ethanol intake in the rat; tolerance development to acamprosate but not to Org24598. Addiction biology 20120901
The cost-effectiveness of tailored, postal feedback on general practitioners' prescribing of pharmacotherapies for alcohol dependence. Drug and alcohol dependence 20120801
Trajectory analyses in alcohol treatment research. Alcoholism, clinical and experimental research 20120801
Polyamine modulation of NMDARs as a mechanism to reduce effects of alcohol dependence. Recent patents on CNS drug discovery 20120801
Novel medication targets for the treatment of alcoholism: preclinical studies. Recent patents on CNS drug discovery 20120801
Introduction to the special issue 'Pharmacotherapies for the treatment of alcohol abuse and dependence' and a summary of patents targeting other neurotransmitter systems. Recent patents on CNS drug discovery 20120801
Does session attendance by a supportive significant other predict outcomes in individual treatment for alcohol use disorders? Alcoholism, clinical and experimental research 20120701
Pharmacotherapy of alcohol use disorders by the Veterans Health Administration: patterns of receipt and persistence. Psychiatric services (Washington, D.C.) 20120701
Pharmacotherapy for adolescent alcohol use disorder. CNS drugs 20120701
Commentary on the study: impact of depressive symptoms on future alcohol use in patients with co-occurring bipolar disorder and alcohol dependence: a prospective analysis in an 8-week randomized controlled trial of acamprosate (Prisciandaro et al.). Alcoholism, clinical and experimental research 20120601
Pharmacogenetically driven treatments for alcoholism: are we there yet? CNS drugs 20120601
Ethanol withdrawal-induced brain metabolites and the pharmacological effects of acamprosate in mice lacking ENT1. Neuropharmacology 20120601
Strategies for evaluating the economic value of drugs in alcohol dependence treatment. Drug and alcohol dependence 20120501
Influence of ionization source design on matrix effects during LC-ESI-MS/MS analysis. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120415
Alcoholic liver disease. World journal of hepatology 20120327
Acamprosate for alcohol dependence: a sex-specific meta-analysis based on individual patient data. Alcoholism, clinical and experimental research 20120301
Baseline trajectories of heavy drinking and their effects on postrandomization drinking in the COMBINE Study: empirically derived predictors of drinking outcomes during treatment. Alcohol (Fayetteville, N.Y.) 20120301
Impact of depressive symptoms on future alcohol use in patients with co-occurring bipolar disorder and alcohol dependence: a prospective analysis in an 8-week randomized controlled trial of acamprosate. Alcoholism, clinical and experimental research 20120301
Glutamatergic medications for the treatment of drug and behavioral addictions. Pharmacology, biochemistry, and behavior 20120201
Acamprosate modulates experimental autoimmune encephalomyelitis. Inflammopharmacology 20120201
A randomized, double-blind, placebo-controlled clinical trial of acamprosate in alcohol-dependent individuals with bipolar disorder: a preliminary report. Bipolar disorders 20120201
Sleep disturbance in alcoholism: proposal of a simple measurement, and results from a 24-week randomized controlled study of alcohol-dependent patients assessing acamprosate efficacy. Alcohol and alcoholism (Oxford, Oxfordshire) 20120101
Pharmacogenetics of alcoholism: a clinical neuroscience perspective. Pharmacogenomics 20120101
The role of health systems factors in facilitating access to psychotropic medicines: a cross-sectional analysis of the WHO-AIMS in 63 low- and middle-income countries. PLoS medicine 20120101
Tinnitus. BMJ clinical evidence 20120101
Role of acamprosate in sensorineural tinnitus. Indian journal of pharmacology 20120101
Acamprosate for treatment of alcohol dependence: mechanisms, efficacy, and clinical utility. Therapeutics and clinical risk management 20120101
Anti-Alcohol and Anxiolytic Properties of a New Chemical Entity, GET73. Frontiers in psychiatry 20120101
Cost-effectiveness of peer-delivered interventions for cocaine and alcohol abuse among women: a randomized controlled trial. PloS one 20120101
Do placebo response rates from cessation trials inform on strength of addictions? International journal of environmental research and public health 20120101
Dihydrocodeine/Agonists for alcohol dependents. Frontiers in psychiatry 20120101
Influence of cue exposure on inhibitory control and brain activation in patients with alcohol dependence. Frontiers in human neuroscience 20120101
Plasticity and mTOR: towards restoration of impaired synaptic plasticity in mTOR-related neurogenetic disorders. Neural plasticity 20120101
Exercise and physical activity in the therapy of substance use disorders. TheScientificWorldJournal 20120101
Deep brain stimulation of nucleus accumbens region in alcoholism affects reward processing. PloS one 20120101
Pharmacological management of binge eating disorder: current and emerging treatment options. Therapeutics and clinical risk management 20120101
Treatments for alcohol-related disorders in China: a developing story. Alcohol and alcoholism (Oxford, Oxfordshire) 20120101
Long-lasting alterations in membrane properties, k(+) currents, and glutamatergic synaptic currents of nucleus accumbens medium spiny neurons in a rat model of alcohol dependence. Frontiers in neuroscience 20120101
Electroacupuncture decreases excessive alcohol consumption involving reduction of FosB/ΔFosB levels in reward-related brain regions. PloS one 20120101
Prognostic factors during outpatient treatment for alcohol dependence: cohort study with 6 months of treatment follow-up. Alcohol and alcoholism (Oxford, Oxfordshire) 20120101
An open-label naturalistic pilot study of acamprosate in youth with autistic disorder. Journal of child and adolescent psychopharmacology 20111201
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). PLoS computational biology 20111201
Calcium acamprosate: a triclinic polymorph. Acta crystallographica. Section E, Structure reports online 20111201
[Current strategies for treatment of alcohol problems]. La Revue du praticien 20111201
[Meta-analysis of pharmacological therapy with acamprosate, naltrexone, and disulfiram--a systematic review]. Ugeskrift for laeger 20111128
Predictors of clinical trial dropout in individuals with co-occurring bipolar disorder and alcohol dependence. Drug and alcohol dependence 20111101
The effects of combined acamprosate and integrative behaviour therapy in the outpatient treatment of alcohol dependence: a randomized controlled trial. Drug and alcohol dependence 20111101
Synaptic and morphological neuroadaptations in the putamen associated with long-term, relapsing alcohol drinking in primates. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20111101
Tryptophan in alcoholism treatment I: kynurenine metabolites inhibit the rat liver mitochondrial low Km aldehyde dehydrogenase activity, elevate blood acetaldehyde concentration and induce aversion to alcohol. Alcohol and alcoholism (Oxford, Oxfordshire) 20111101
Opioid antagonists for the treatment of alcohol dependence. American family physician 20111101
[Baclofen for alcohol addiction]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20111101
An open-label trial of acamprosate in the treatment of pathological gambling. Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists 20111101
Evidence-based guidelines for mental, neurological, and substance use disorders in low- and middle-income countries: summary of WHO recommendations. PLoS medicine 20111101
Involvement of the atrial natriuretic peptide transcription factor GATA4 in alcohol dependence, relapse risk and treatment response to acamprosate. The pharmacogenomics journal 20111001
A LC-MS analysis of acamprosate from human plasma: pharmacokinetic application. Drug testing and analysis 20111001
Acamprosate-responsive brain sites for suppression of ethanol intake and preference. American journal of physiology. Regulatory, integrative and comparative physiology 20111001
The mGluR5 antagonist MPEP elevates accumbal dopamine and glycine levels; interaction with strychnine-sensitive glycine receptors. Addiction biology 20111001
Therapeutic drug monitoring for drugs used in the treatment of substance-related disorders: literature review using a therapeutic drug monitoring appropriateness rating scale. Therapeutic drug monitoring 20111001
Circadian and acamprosate modulation of elevated ethanol drinking in mPer2 clock gene mutant mice. Chronobiology international 20111001
[Good effect of drug therapy against alcoholism]. Lakartidningen 20111001
Comorbid anxiety disorders and baseline medication regimens predict clinical outcomes in individuals with co-occurring bipolar disorder and alcohol dependence: Results of a randomized controlled trial. Psychiatry research 20110815
A literature review of cost-benefit analyses for the treatment of alcohol dependence. International journal of environmental research and public health 20110801
Effects of acamprosate on cognition in a treatment study of patients with schizophrenia spectrum disorders and comorbid alcohol dependence. The Journal of nervous and mental disease 20110701
How cognitive assessment through clinical neurophysiology may help optimize chronic alcoholism treatment. Neurophysiologie clinique = Clinical neurophysiology 20110701
Long-term γ-hydroxybutyric acid (GHB) and disulfiram combination therapy in GHB treatment-resistant chronic alcoholics. International journal of environmental research and public health 20110701
The case for considering quality of life in addiction research and clinical practice. Addiction science & clinical practice 20110701
Using medication-assisted treatment for substance use disorders: evidence of barriers and facilitators of implementation. Addictive behaviors 20110601
Self-efficacy change as a mediator of associations between therapeutic bond and one-year outcomes in treatments for alcohol dependence. Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors 20110601
Acamprosate attenuates cue-induced reinstatement of nicotine-seeking behavior in rats. Behavioural pharmacology 20110601
Alcohol dependence treatments: comprehensive healthcare costs, utilization outcomes, and pharmacotherapy persistence. The American journal of managed care 20110601
Extended-release naltrexone for alcohol dependence: persistence and healthcare costs and utilization. The American journal of managed care 20110601
Pharmacologically induced alcohol craving in treatment seeking alcoholics correlates with alcoholism severity, but is insensitive to acamprosate. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20110501
Marked reduction of heavy drinking did not reduce nicotine use over 1 year in a clinical sample of alcohol-dependent patients. Pharmacopsychiatry 20110501
Medicare prescription drug plan coverage of pharmacotherapies for opioid and alcohol dependence in WA. Drug and alcohol dependence 20110401
A double-blind, placebo-controlled pilot trial of acamprosate for the treatment of cocaine dependence. Addictive behaviors 20110301
Baseline trajectories of drinking moderate acamprosate and naltrexone effects in the COMBINE study. Alcoholism, clinical and experimental research 20110301
Addiction treatment: level of care determination. Primary care 20110301
Effectiveness of acamprosate in the treatment of alcohol dependence. American family physician 20110301
Mammalian molecular clocks. Experimental neurobiology 20110301
Acamprosate reduces ethanol drinking behaviors and alters the metabolite profile in mice lacking ENT1. Neuroscience letters 20110225
Moderating effects of a craving intervention on the relation between negative mood and heavy drinking following treatment for alcohol dependence. Journal of consulting and clinical psychology 20110201
Acamprosate reduces risk of return to drinking after detoxification, but is similarly effective to naltrexone. Evidence-based mental health 20110201
ACP Journal Club. Review: Acamprosate increases abstinence in patients with alcohol dependence. Annals of internal medicine 20110118
Acamprosate in the treatment of binge eating disorder: a placebo-controlled trial. The International journal of eating disorders 20110101
Alcohol-use disorders and depression: results from individual patient data meta-analysis of the acamprosate-controlled studies. Alcohol and alcoholism (Oxford, Oxfordshire) 20110101
Alcohol dependence: analysis of factors associated with retention of patients in outpatient treatment. Alcohol and alcoholism (Oxford, Oxfordshire) 20110101
Does family history of alcoholism moderate naltrexone's effects on alcohol use? Journal of studies on alcohol and drugs 20110101
Status of disulfiram in present day alcoholic deaddiction therapy. Indian journal of psychiatry 20110101
GABAergic and glutamatergic modulation in binge eating: therapeutic approach. Current pharmaceutical design 20110101
New trends in tinnitus management. The open neurology journal 20110101
A role for accumbal glycine receptors in modulation of dopamine release by the glycine transporter-1 inhibitor org25935. Frontiers in psychiatry 20110101
Poly-substance use and antisocial personality traits at admission predict cumulative retention in a buprenorphine programme with mandatory work and high compliance profile. BMC psychiatry 20110101
Urinary ethyl glucuronide and ethyl sulfate testing for recent drinking in alcohol-dependent outpatients treated with acamprosate or placebo. Alcohol and alcoholism (Oxford, Oxfordshire) 20110101
Predictive value of obsessive-compulsive drinking scale (OCDS) for outcome in alcohol-dependent inpatients: results of a 24-month follow-up study. Substance abuse treatment, prevention, and policy 20110101
Acamprosate and Baclofen were Not Effective in the Treatment of Pathological Gambling: Preliminary Blind Rater Comparison Study. Frontiers in psychiatry 20110101
Pharmacological treatment of insomnia in alcohol recovery: a systematic review. Alcohol and alcoholism (Oxford, Oxfordshire) 20110101
Relapse prevention for addictive behaviors. Substance abuse treatment, prevention, and policy 20110101
Modeling the cost-effectiveness of health care systems for alcohol use disorders: how implementation of eHealth interventions improves cost-effectiveness. Journal of medical Internet research 20110101
Cocaine Addiction Treatments to improve Control and reduce Harm (CATCH): new pharmacological treatment options for crack-cocaine dependence in the Netherlands. BMC psychiatry 20110101
Towards the development of novel Trypanosoma brucei RNA editing ligase 1 inhibitors. BMC pharmacology 20110101
Treatment of decompensated alcoholic liver disease. International journal of hepatology 20110101
Diabetes and psychiatric disorders. Indian journal of endocrinology and metabolism 20110101
Alpe adria report 2010 - conclusions and recommendations for the treatment of alcohol dependence. Frontiers in psychiatry 20110101
Neurosteroid Binding Sites on the GABA(A) Receptor Complex as Novel Targets for Therapeutics to Reduce Alcohol Abuse and Dependence. Advances in pharmacological sciences 20110101
HOMER: a human organ-specific molecular electronic repository. BMC bioinformatics 20110101
Alternative splicing of AMPA subunits in prefrontal cortical fields of cynomolgus monkeys following chronic ethanol self-administration. Frontiers in psychiatry 20110101
Medical treatment of alcohol dependence: a systematic review. International journal of psychiatry in medicine 20110101
[Cochrane review about the effect of acamprosate]. Ugeskrift for laeger 20101206
Emerging drugs to treat alcoholism. Expert opinion on emerging drugs 20101201
Percentage of subjects with no heavy drinking days: evaluation as an efficacy endpoint for alcohol clinical trials. Alcoholism, clinical and experimental research 20101201
Acamprosate calcium as augmentation therapy for anxiety disorders. The Annals of pharmacotherapy 20101201
Cost evaluation of evidence-based treatments. Addiction science & clinical practice 20101201
Brief report: acamprosate in fragile X syndrome. Journal of autism and developmental disorders 20101101
Network support as a prognostic indicator of drinking outcomes: the COMBINE Study. Journal of studies on alcohol and drugs 20101101
Individualised treatment in alcohol-dependent patients. European archives of psychiatry and clinical neuroscience 20101101
[The role of the glutamatergic system in the pathogenesis and treatment of alcohol dependence]. Postepy higieny i medycyny doswiadczalnej (Online) 20101025
Glycine transporter-1 blockade leads to persistently reduced relapse-like alcohol drinking in rats. Biological psychiatry 20101015
Effect of acamprosate on magnetic resonance spectroscopy measures of central glutamate in detoxified alcohol-dependent individuals: a randomized controlled experimental medicine study. Archives of general psychiatry 20101004
Effect of early and late compliance on the effectiveness of acamprosate in the treatment of alcohol dependence. Journal of substance abuse treatment 20101001
Gender differences in alcohol treatment: an analysis of outcome from the COMBINE study. Alcoholism, clinical and experimental research 20101001
Acamprosate for alcohol dependence. The Cochrane database of systematic reviews 20100908
Acamprosate modulates alcohol-induced hippocampal NMDA receptors and brain microsomal Ca2+-ATPase but induces oxidative stress in rat. The Journal of membrane biology 20100901
Gambling on acamprosate: a case report. The Journal of clinical psychiatry 20100901
Acamprosate determinations in plasma and cerebrospinal fluid after multiple dosing measured by liquid chromatography-mass spectroscopy: a pharmacokinetic study in healthy volunteers. Therapeutic drug monitoring 20100801
The effect of alcohol treatment on social costs of alcohol dependence: results from the COMBINE study. Medical care 20100501
Molecular basis and current treatment for alcoholic liver disease. International journal of environmental research and public health 20100501
The adoption of alcohol pharmacotherapies in the Clinical Trials Network: the influence of research network participation. Journal of substance abuse treatment 20100401
Revisiting the cost-effectiveness of the COMBINE study for alcohol dependent patients: the patient perspective. Medical care 20100401
Pharmacotherapy of alcohol use disorders in the Veterans Health Administration. Psychiatric services (Washington, D.C.) 20100401
Naltrexone and combined behavioral intervention effects on trajectories of drinking in the COMBINE study. Drug and alcohol dependence 20100301
Acamprosate. Expert opinion on drug metabolism & toxicology 20100301
The clock gene PER2 and sleep problems: association with alcohol consumption among Swedish adolescents. Upsala journal of medical sciences 20100301
Acamprosate: a prototypic neuromodulator in the treatment of alcohol dependence. CNS & neurological disorders drug targets 20100301
Pharmacotherapies for alcoholism: the old and the new. CNS & neurological disorders drug targets 20100301
Glycine receptors in the nucleus accumbens involved in the ethanol intake-reducing effect of acamprosate. Alcoholism, clinical and experimental research 20100101
Glycine receptors involved in acamprosate's modulation of accumbal dopamine levels: an in vivo microdialysis study. Alcoholism, clinical and experimental research 20100101
The neurobiology, clinical efficacy and safety of acamprosate in the treatment of alcohol dependence. Expert opinion on drug safety 20100101
Neurobiological mechanisms of addiction: focus on corticotropin-releasing factor. Current opinion in investigational drugs (London, England : 2000) 20100101
The effects of current subsyndromal psychiatric symptoms or past psychopathology on alcohol dependence treatment outcomes and acamprosate efficacy. The American journal on addictions 20100101
Identification of molecular targets associated with ethanol toxicity and implications in drug development. Current pharmaceutical design 20100101
Internal medicine residency training for unhealthy alcohol and other drug use: recommendations for curriculum design. BMC medical education 20100101
Why is disulfiram superior to acamprosate in the routine clinical setting? A retrospective long-term study in 353 alcohol-dependent patients. Alcohol and alcoholism (Oxford, Oxfordshire) 20100101
Possible new ways in the pharmacological treatment of bipolar disorder and comorbid alcoholism. Neuropsychiatric disease and treatment 20100101
Providing competency-based family medicine residency training in substance abuse in the new millennium: a model curriculum. BMC medical education 20100101
Acamprosate: how, where, and for whom does it work? Mechanism of action, treatment targets, and individualized therapy. Current pharmaceutical design 20100101
Supervised disulfiram as adjunct to psychotherapy in alcoholism treatment. Current pharmaceutical design 20100101
The scope of costs in alcohol studies: Cost-of-illness studies differ from economic evaluations. Cost effectiveness and resource allocation : C/E 20100101
[Impact of functional social support for abstinence after inpatient detoxification]. Neuropsychiatrie : Klinik, Diagnostik, Therapie und Rehabilitation : Organ der Gesellschaft Osterreichischer Nervenarzte und Psychiater 20100101
Tinnitus psychopharmacology: A comprehensive review of its pathomechanisms and management. Neuropsychiatric disease and treatment 20100101
[Update on current care guidelines: treatment of alcohol abuse]. Duodecim; laaketieteellinen aikakauskirja 20100101
Retrospective review of acute acamprosate exposures to a poison control system. The American journal on addictions 20100101
Clinical predictors of outcome from an Australian pharmacological relapse prevention trial. Alcohol and alcoholism (Oxford, Oxfordshire) 20100101
The pharmacotherapy of alcohol dependence: a state of the art review. Mens sana monographs 20100101
Comparison of healthcare utilization among patients treated with alcoholism medications. The American journal of managed care 20100101
Reduction by the Positive Allosteric Modulator of the GABA(B) Receptor, GS39783, of Alcohol Self-Administration in Sardinian Alcohol-Preferring Rats Exposed to the 'Sipper' Procedure. Frontiers in psychiatry 20100101
The Effects of Naltrexone Among Alcohol Non-Abstainers: Results from the COMBINE Study. Frontiers in psychiatry 20100101
Substance use and addiction research in India. Indian journal of psychiatry 20100101
The effect of acamprosate on alcohol craving and correlation with hypothalamic pituitary adrenal (HPA) axis hormones and beta-endorphin. Brain research 20091211
Naltrexone for the treatment of alcohol dependence among African Americans: results from the COMBINE Study. Drug and alcohol dependence 20091201
Packages of care for alcohol use disorders in low- and middle-income countries. PLoS medicine 20091001
Alcohol dependence: after the withdrawal phase. Long-term abstinence: better health and psychosocial status. Psychosocial support for a chronic disorder. Some drugs are useful adjuncts to medical support. Prescrire international 20091001
Blood glucose level, alcohol heavy drinking, and alcohol craving during treatment for alcohol dependence: results from the Combined Pharmacotherapies and Behavioral Interventions for Alcohol Dependence (COMBINE) Study. Alcoholism, clinical and experimental research 20090901
[Addiction in DSM V and ICD-11 state of the art]. Fortschritte der Neurologie-Psychiatrie 20090901
Effects of nicotine and illicit substance use on alcoholism treatment outcomes and acamprosate efficacy. Journal of addiction medicine 20090901
Carisbamate, a novel antiepileptic candidate compound, attenuates alcohol intake in alcohol-preferring rats. Alcoholism, clinical and experimental research 20090801
Cue-induced alcohol-seeking behaviour is reduced by disrupting the reconsolidation of alcohol-related memories. Psychopharmacology 20090801
The effects of acamprosate on alcohol-cue reactivity and alcohol priming in dependent patients: a randomized controlled trial. Psychopharmacology 20090701
Predicting the effect of naltrexone and acamprosate in alcohol-dependent patients using genetic indicators. Addiction biology 20090701
[Interaction between Saint Johns Wort and alcohol deterrents?]. Lakartidningen 20090701
Acamprosate and naltrexone treatment effects on ethanol and sucrose seeking and intake in ethanol-dependent and nondependent rats. Psychopharmacology 20090601
[Pharmacotherapy of substance dependence and withdrawal syndromes]. Therapeutische Umschau. Revue therapeutique 20090601
Treatment of alcohol dependence. The Ceylon medical journal 20090601
Meta-analyses of placebo-controlled trials of acamprosate for the treatment of alcohol dependence: impact of the combined pharmacotherapies and behavior interventions study. Journal of addiction medicine 20090601
Proton pump inhibitors and risk of gastric cancer: a population-based cohort study. British journal of cancer 20090505
The implications of medication development in the treatment of substance use disorders in developing countries. Current opinion in psychiatry 20090501
Management of alcoholic liver disease. Clinics in liver disease 20090501
Review of topiramate: an antiepileptic for the treatment of alcohol dependence. Current drug abuse reviews 20090501
Sample bias from different recruitment strategies in a randomised controlled trial for alcohol dependence. Drug and alcohol review 20090501
Searching for responders to acamprosate and naltrexone in alcoholism treatment: rationale and design of the PREDICT study. Alcoholism, clinical and experimental research 20090401
Tinnitus: characteristics, causes, mechanisms, and treatments. Journal of clinical neurology (Seoul, Korea) 20090301
Alcohol and opioid dependence medications: prescription trends, overall and by physician specialty. Drug and alcohol dependence 20090101
The state of pharmacotherapy for the treatment of alcohol dependence. Journal of substance abuse treatment 20090101
Expectancy in double-blind placebo-controlled trials: an example from alcohol dependence. Psychotherapy and psychosomatics 20090101
Initiating acamprosate within-detoxification versus post-detoxification in the treatment of alcohol dependence. Addictive behaviors 20090101
Socioeconomic status and survival of cirrhosis patients: a Danish nationwide cohort study. BMC gastroenterology 20090101
Determinants of improvement in quality of life of alcohol-dependent patients during an inpatient withdrawal programme. International journal of medical sciences 20090101
A chemogenomics view on protein-ligand spaces. BMC bioinformatics 20090101
Counteracting incentive sensitization in severe alcohol dependence using deep brain stimulation of the nucleus accumbens: clinical and basic science aspects. Frontiers in human neuroscience 20090101
Open-label trial of acamprosate as a treatment for anxiety. Primary care companion to the Journal of clinical psychiatry 20090101
Pharmacokinetics of acamprosate calcium in healthy Chinese subjects after oral administration of three dosage levels. Arzneimittel-Forschung 20090101
Impulse control disorders in Parkinson's disease. F1000 medicine reports 20090101
Tinnitus. BMJ clinical evidence 20090101
Successful acamprosate treatment of alcohol dependence in schizophrenia. Schizophrenia research 20081201
The influence of various glutamate receptors antagonists on anxiety-like effect of ethanol withdrawal in a plus-maze test in rats. European journal of pharmacology 20081119
Glutamatergic dysfunction in schizophrenia: from basic neuroscience to clinical psychopharmacology. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20081101
Acute effects of acamprosate and MPEP on ethanol Drinking-in-the-Dark in male C57BL/6J mice. Alcoholism, clinical and experimental research 20081101
Do patients with alcohol dependence respond to placebo? Results from the COMBINE Study. Journal of studies on alcohol and drugs 20081101
Opioid antagonists for pharmacological treatment of alcohol dependence - a critical review. Current drug abuse reviews 20081101
Introduction. The neurobiology of drug addiction: new vistas. Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20081012
Effects of naltrexone and acamprosate on alcohol-induced NGFI-A expression in mouse brain. Neurochemical research 20081001
Intermittent access to 20% ethanol induces high ethanol consumption in Long-Evans and Wistar rats. Alcoholism, clinical and experimental research 20081001
Preserved DNA from past clinical trials yields new information about a subtype of alcoholism. Current psychiatry reports 20081001
Cost and cost-effectiveness of the COMBINE study in alcohol-dependent patients. Archives of general psychiatry 20081001
Acamprosate attenuates the handling induced convulsions during alcohol withdrawal in Swiss Webster mice. Physiology & behavior 20080903
Metabotropic glutamate receptor 5 (mGluR5) regulation of ethanol sedation, dependence and consumption: relationship to acamprosate actions. The international journal of neuropsychopharmacology 20080901
Relationship between medication adherence and treatment outcomes: the COMBINE study. Alcoholism, clinical and experimental research 20080901
An intervention for treating alcohol dependence: relating elements of Medical Management to patient outcomes with implications for primary care. Annals of family medicine 20080901
Aminomethylpiperazines as selective urotensin antagonists. Bioorganic & medicinal chemistry letters 20080815
Pharmacotherapy of schizophrenia with comorbid substance use disorder--reviewing the evidence and clinical recommendations. Progress in neuro-psychopharmacology & biological psychiatry 20080801
Analysis of acamprosate in beagle dog plasma by LC-MS-MS. Archives of pharmacal research 20080801
Acamprosate: recent findings and future research directions. Alcoholism, clinical and experimental research 20080701
Do acamprosate or naltrexone have an effect on daily drinking by reducing craving for alcohol? Addiction (Abingdon, England) 20080601
Investigation of the relationship between in vitro and in vivo release behaviors of acamprosate from enteric-coated tablets. Archives of pharmacal research 20080601
The effects of maternally administered methadone, buprenorphine and naltrexone on offspring: review of human and animal data. Current neuropharmacology 20080601
[Pharmacotherapy of alcohol dependence]. MMW Fortschritte der Medizin 20080519
[Alcohol dependence: diagnosis and treatment]. La Revue de medecine interne 20080401
Cloninger's typology and treatment outcome in alcohol-dependent subjects during pharmacotherapy with naltrexone. Addiction biology 20080301
The effect of acamprosate on alcohol and food craving in patients with alcohol dependence. Drug and alcohol dependence 20080301
Drugs for relapse prevention of alcoholism: ten years of progress. Trends in pharmacological sciences 20080301
A microdialysis study of extracellular levels of acamprosate and naltrexone in the rat brain following acute and repeated administration. Addiction biology 20080301
Alcohol related changes in regulation of NMDA receptor functions. Current neuropharmacology 20080301
Pharmacodynamics of memantine: an update. Current neuropharmacology 20080301
Acamprosate: safety and tolerability in the treatment of alcohol dependence. Journal of addiction medicine 20080301
Effect of chronic acamprosate treatment on voluntary alcohol intake and beta-endorphin plasma levels in rats selectively bred for high alcohol preference. Neuroscience letters 20080206
Effects of acamprosate on neuronal receptors and ion channels expressed in Xenopus oocytes. Alcoholism, clinical and experimental research 20080201
An evaluation of mu-opioid receptor (OPRM1) as a predictor of naltrexone response in the treatment of alcohol dependence: results from the Combined Pharmacotherapies and Behavioral Interventions for Alcohol Dependence (COMBINE) study. Archives of general psychiatry 20080201
[Unhealthy alcohol use in the elderly--current screening and treatment strategies]. Fortschritte der Neurologie-Psychiatrie 20080201
From the neurobiologic basis of alcohol dependency to pharmacologic treatment strategies: bridging the knowledge gap. Southern medical journal 20080201
Substance abuse and schizophrenia: pharmacotherapeutic intervention. Journal of substance abuse treatment 20080101
[Pharmacotherapy of schizophrenia and comorbid substance use disorder. A systematic review]. Der Nervenarzt 20080101
Glutamatergic substrates of drug addiction and alcoholism. Biochemical pharmacology 20080101
Update on neuropharmacological treatments for alcoholism: scientific basis and clinical findings. Biochemical pharmacology 20080101
A randomized, multicentre, open-label, comparative trial of disulfiram, naltrexone and acamprosate in the treatment of alcohol dependence. Alcohol and alcoholism (Oxford, Oxfordshire) 20080101
NMDA receptor blockade: a novel avenue for tobacco intervention? Medical hypotheses 20080101
Combined pharmacotherapies and behavioral interventions for alcohol dependence (The COMBINE Study): examination of posttreatment drinking outcomes. Journal of studies on alcohol and drugs 20080101
Acamprosate supports abstinence, naltrexone prevents excessive drinking: evidence from a meta-analysis with unreported outcomes. Journal of psychopharmacology (Oxford, England) 20080101
Acamprosate efficacy in alcohol-dependent patients: summary of results from three pivotal trials. The American journal on addictions 20080101
World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for Biological Treatment of Substance Use and Related Disorders, Part 1: Alcoholism. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry 20080101
Neurobiology and treatment in alcoholism--recent findings regarding Lesch's typology of alcohol dependence. Alcohol and alcoholism (Oxford, Oxfordshire) 20080101
Association between single nucleotide polymorphisms in the mu opioid receptor gene (OPRM1) and self-reported responses to alcohol in American Indians. BMC medical genetics 20080101
[Pharmacological review of alcoholic dependence treatment]. Vertex (Buenos Aires, Argentina) 20080101
State policy influence on the early diffusion of buprenorphine in community treatment programs. Substance abuse treatment, prevention, and policy 20080101
The efficacy of acamprosate and naltrexone in the treatment of alcohol dependence: a relative benefits analysis of randomized controlled trials. The American journal of drug and alcohol abuse 20080101
Treatment of alcohol dependence in patients with co-morbid major depressive disorder--predictors for the outcomes with memantine and escitalopram medication. Substance abuse treatment, prevention, and policy 20080101
Effectiveness of sequential combined treatment in comparison with treatment as usual in preventing relapse in alcohol dependence. Alcohol and alcoholism (Oxford, Oxfordshire) 20080101
Activation instead of blocking mesolimbic dopaminergic reward circuitry is a preferred modality in the long term treatment of reward deficiency syndrome (RDS): a commentary. Theoretical biology & medical modelling 20080101
[Recent results in relaps prevention of alcoholism with Disulfiram]. Neuropsychiatrie : Klinik, Diagnostik, Therapie und Rehabilitation : Organ der Gesellschaft Osterreichischer Nervenarzte und Psychiater 20080101
Inhalant abuse: A clinic-based study. Indian journal of psychiatry 20080101
Agenda for specialty section in addiction medicine. Indian journal of psychiatry 20080101
New therapies for alcohol dependence open options for office-based treatment. JAMA 20071205
Acamprosate attenuates cocaine- and cue-induced reinstatement of cocaine-seeking behavior in rats. Psychopharmacology 20071201
Outpatient Long-term Intensive Therapy for Alcoholics (OLITA): a successful biopsychosocial approach to the treatment of alcoholism. Dialogues in clinical neuroscience 20071201
Therapeutic options and challenges for substances of abuse. Dialogues in clinical neuroscience 20071201
Acamprosate in the treatment of alcohol dependence: clinical and economic considerations. Expert review of neurotherapeutics 20071101
Naltrexone long-acting formulation in the treatment of alcohol dependence. Therapeutics and clinical risk management 20071001
The psychiatric management of patients with alcohol dependence. Current treatment options in neurology 20070901
Acamprosate in alcohol dependence: implications of a unique mechanism of action. Journal of addiction medicine 20070901
Psychometrics of the Drinker Inventory of Consequences (DrInC). Addictive behaviors 20070801
Pharmacological characterization of glycine-activated currents in HEK 293 cells expressing N-methyl-D-aspartate NR1 and NR3 subunits. The Journal of pharmacology and experimental therapeutics 20070801
Tinnitus. BMJ clinical evidence 20070801
The effect of naltrexone and acamprosate on cue-induced craving, autonomic nervous system and neuroendocrine reactions to alcohol-related cues in alcoholics. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20070701
The treatment of alcohol dependence. Current opinion in psychiatry 20070501
Baclofen blocks expression and sensitization of anxiety-like behavior in an animal model of repeated stress and ethanol withdrawal. Alcoholism, clinical and experimental research 20070401
Acamprosate and primitive reflexes. The Annals of pharmacotherapy 20070401
An eight-week, open-label, prospective case series of acamprosate calcium as monotherapy for patients with comorbid anxiety symptoms and alcohol misuse: an evaluation for alcohol sobriety and anxiolysis. Psychiatry (Edgmont (Pa. : Township)) 20070401
Measuring economic outcomes of alcohol treatment using the Economic Form 90. Journal of studies on alcohol and drugs 20070301
Emerging approaches to managing alcohol dependence. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20070301
Improving adherence in patients with alcohol dependence: a new role for pharmacists. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20070301
Alcohol dependence and pharmacologic treatment. Introduction. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20070301
Schizophrenia and co-occurring substance use disorder. The American journal of psychiatry 20070301
Evidence for the role of dopamine D3 receptors in oral operant alcohol self-administration and reinstatement of alcohol-seeking behavior in mice. Addiction biology 20070301
Influence of age at drinking onset on the alcohol deprivation effect and stress-induced drinking in female rats. Pharmacology, biochemistry, and behavior 20070201
Preclinical and clinical pharmacology of alcohol dependence. Fundamental & clinical pharmacology 20070201
Alcohol withdrawal syndrome: how to predict, prevent, diagnose and treat it. Prescrire international 20070201
[Neurobiological mechanisms and pharmacological treatment options for alcohol craving]. Fortschritte der Neurologie-Psychiatrie 20070101
[Pharmacological relapse prevention in alcohol and tobacco dependence]. Der Internist 20070101
Glutamate-modulating drugs & the treatment of mental disorders. Journal of psychosocial nursing and mental health services 20070101
Therapeutics for alcoholism: what's the future? Drug and alcohol review 20070101
Consideration of acamprosate for treatment of amyotrophic lateral sclerosis. Medical hypotheses 20070101
Prescription procedures in medication for relapse prevention after inpatient treatment for alcohol use disorders in Switzerland. Alcohol and alcoholism (Oxford, Oxfordshire) 20070101
Results from two pharmacotherapy trials show alcoholic smokers were more severely alcohol dependent but less prone to relapse than alcoholic non-smokers. Alcohol and alcoholism (Oxford, Oxfordshire) 20070101
Factors predictive of alcohol abstention after resident detoxication among alcoholics followed in an hospital outpatient center. Gastroenterologie clinique et biologique 20070101
Treatment of tinnitus with acamprosate. Progress in brain research 20070101
Treating substance abuse in primary care: a demonstration project. International journal of integrated care 20070101
Somatic configuration: a model for an integrated approach to the understanding of disease. Substance use & misuse 20070101
The application of machine learning techniques as an adjunct to clinical decision making in alcohol dependence treatment. Substance use & misuse 20070101
Medication assisted treatment of drug abuse and dependence: global availability and utilization. Recent patents on anti-infective drug discovery 20070101
Pharmacoprophylaxis of alcohol dependence: Review and update Part I: Pharmacology. Indian journal of psychiatry 20070101
Pharmacoprophylaxis of alcohol dependence: Review and update Part II: Efficacy. Indian journal of psychiatry 20070101
Unusual side effects with acamprosate. Indian journal of psychiatry 20070101
[Drugs against alcohol abuse]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20061214
New pharmacological approaches for the treatment of alcoholism. Expert opinion on pharmacotherapy 20061201
Trends in the adoption of medications for alcohol dependence. Journal of clinical psychopharmacology 20061201
Combining psychosocial treatment with pharmacotherapy for alcohol dependence. Journal of clinical psychopharmacology 20061201
Bipolar disorder and comorbid alcoholism: prevalence rate and treatment considerations. Bipolar disorders 20061201
Substance use disorders and Schizophrenia: a question of shared glutamatergic mechanisms. Neurotoxicity research 20061201
Acamprosate: a new tool in the battle against alcohol dependence. Neuropsychiatric disease and treatment 20061201
Use of pharmacotherapies for the management of addictive behaviours in Australian clinical practice. Addictive behaviors 20061101
The mechanistic classification of addictive drugs. PLoS medicine 20061101
Evidence of a flip-flop phenomenon in acamprosate pharmacokinetics: an in vivo study in rats. Biopharmaceutics & drug disposition 20061001
Naltrexone versus acamprosate in the treatment of alcohol dependence: A multi-centre, randomized, double-blind, placebo-controlled trial. Addiction (Abingdon, England) 20061001
Choosing the right medication for the treatment of alcoholism. Current psychiatry reports 20061001
Which treatment for alcohol dependence: naltrexone, acamprosate and/or behavioural intervention? Expert opinion on pharmacotherapy 20061001
Pharmacological treatment of alcohol dependence: target symptoms and target mechanisms. Pharmacology & therapeutics 20060901
Effects of acamprosate on sleep during alcohol withdrawal: A double-blind placebo-controlled polysomnographic study in alcohol-dependent subjects. Alcoholism, clinical and experimental research 20060901
Effects of treatment with acamprosate on beta-endorphin plasma concentration in humans with high alcohol preference. Neuroscience letters 20060814
Effect of oral acamprosate on abstinence in patients with alcohol dependence in a double-blind, placebo-controlled trial: the role of patient motivation. Journal of psychiatric research 20060801
Hypothalamic-pituitary-adrenocortical axis activity: a target of pharmacological anticraving treatment? Biological psychiatry 20060701
Drug adjuncts for treating alcohol dependence. Cleveland Clinic journal of medicine 20060701
Clinically relevant pharmacology of neuropsychiatric drugs approved over the last three years: part I. Journal of psychiatric practice 20060701
Attenuation of cocaine-induced reinstatement of cocaine conditioned place preference by acamprosate. Behavioural pharmacology 20060601
[Maintaining abstinence after alcohol detoxification]. La Revue du praticien 20060531
Combined pharmacotherapies and behavioral interventions for alcohol dependence: the COMBINE study: a randomized controlled trial. JAMA 20060503
What's new in clinical pharmacology and therapeutics. WMJ : official publication of the State Medical Society of Wisconsin 20060501
Pharmacotherapy for alcohol dependence: anticraving medications for relapse prevention. Yonsei medical journal 20060430
A pilot study of oxcarbazepine versus acamprosate in alcohol-dependent patients. Alcoholism, clinical and experimental research 20060401
Tinnitus. Overcoming the noise. Mayo Clinic health letter (English ed.) 20060401
Practical considerations of new drugs: new choices for old problems. The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists 20060401
The BRENDA model: integrating psychosocial treatment and pharmacotherapy for the treatment of alcohol use disorders. Journal of psychiatric practice 20060301
Schedule-induced alcohol drinking: non-selective effects of acamprosate and naltrexone. Addiction biology 20060301
N-methyl-D-aspartate and group I metabotropic glutamate receptors are involved in the expression of ethanol-induced sensitization in mice. Behavioural pharmacology 20060201
New drugs 06, part I. Nursing 20060201
Alcoholism and pathways to recovery: new survey results on views and treatment options. MedGenMed : Medscape general medicine 20060104
Alcoholism and suicidal behavior: a clinical overview. Acta psychiatrica Scandinavica 20060101
Combined acamprosate and naltrexone, with cognitive behavioural therapy is superior to either medication alone for alcohol abstinence: a single centres' experience with pharmacotherapy. Alcohol and alcoholism (Oxford, Oxfordshire) 20060101
Impact of practitioner's training in the management of alcohol dependence: a quasi-experimental 18-month follow-up study. Substance abuse treatment, prevention, and policy 20060101
Extended-release intramuscular naltrexone: a viewpoint by Henry R Kranzler. Drugs 20060101
Is acamprosate use in alcohol dependence treatment reflected in improved subjective health status outcomes beyond cognitive behavioural therapy alone? Journal of addictive diseases 20060101
[Treatment and prevention of alcohol-related problems and evidence based medicine]. Casopis lekaru ceskych 20060101
New achievements and pharmacotherapeutic approaches in the treatment of alcohol dependence. European journal of pharmacology 20051205
Can experimental paradigms and animal models be used to discover clinically effective medications for alcoholism? Addiction biology 20051201
New alcohol abuse drugs emerging. Anti-craving meds are finally here to treat alcohol dependence, recognized as a disease of the brain. Health news (Waltham, Mass.) 20051201
Sleep disturbances, psychiatric disorders, and psychotropic drugs. Dialogues in clinical neuroscience 20051201
Is there evidence for effectiveness of acamprosate in maintaining abstinence in alcohol dependent patients? Psychiatry (Edgmont (Pa. : Township)) 20051201
Changes in the beta-endorphin plasma level after repeated treatment with acamprosate in rats selectively bred for high and low alcohol preference. Neuroscience letters 20051104
Medications for treating alcohol dependence. American family physician 20051101
The efficacy of compliance therapy in pharmacotherapy for alcohol dependence: a randomized controlled trial. Journal of studies on alcohol 20051101
Acamprosate in the treatment of alcohol dependence. Expert opinion on pharmacotherapy 20051001
Production of reactive oxygen species following acute ethanol or acetaldehyde and its reduction by acamprosate in chronically alcoholized rats. European journal of pharmacology 20050927
Increasing leptin precedes craving and relapse during pharmacological abstinence maintenance treatment of alcoholism. Journal of psychiatric research 20050901
The acute anti-craving effect of acamprosate in alcohol-preferring rats is associated with modulation of the mesolimbic dopamine system. Addiction biology 20050901
Acamprosate. Nursing times 20050901
Challenges and opportunities for medications development in alcoholism: an international perspective on collaborations between academia and industry. Alcoholism, clinical and experimental research 20050801
A neuroendocrinological hypothesis on gender effects of naltrexone in relapse prevention treatment. Pharmacopsychiatry 20050701
Suppression of the HPA axis stress-response: implications for relapse. Alcoholism, clinical and experimental research 20050701
Drug treatment for alcoholism today. The Harvard mental health letter 20050701
Combining treatments for alcoholism: why and how? Journal of studies on alcohol. Supplement 20050701
When worlds collide: blending the divergent traditions of pharmacotherapy and-psychotherapy outcome research. Journal of studies on alcohol. Supplement 20050701
Use of a 'psychotherapy with no pills' treatment condition as part of a combined pharmacotherapy-psychotherapy research study of alcohol dependence. Journal of studies on alcohol. Supplement 20050701
COMBINE genetics study: the pharmacogenetics of alcoholism treatment response: genes and mechanisms. Journal of studies on alcohol. Supplement 20050701
How pilot studies improve large-scale clinical trials: lessons learned from the COMBINE Study. Journal of studies on alcohol. Supplement 20050701
Measurement and choice of drinking outcome variables in the COMBINE Study. Journal of studies on alcohol. Supplement 20050701
Choosing pharmacotherapies for the COMBINE Study--process and procedures: an investigational approach to combination pharmacotherapy for the treatment of alcohol dependence. Journal of studies on alcohol. Supplement 20050701
Rationale for combining acamprosate and naltrexone for treating alcohol dependence. Journal of studies on alcohol. Supplement 20050701
The COMBINE SAFTEE: a structured instrument for collecting adverse events adapted for clinical studies in the alcoholism field. Journal of studies on alcohol. Supplement 20050701
[Does disulfiram still have a role in alcoholism treatment?]. Revue medicale suisse 20050629
The effects of acamprosate and neramexane on cue-induced reinstatement of ethanol-seeking behavior in rat. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20050601
Acamprosate for the treatment of alcohol dependence. Clinical therapeutics 20050601
Repeated-testing of place preference expression for evaluation of anti-craving-drug effects. Amino acids 20050501
Development of medications for alcohol use disorders: recent advances and ongoing challenges. Expert opinion on emerging drugs 20050501
New drug released for alcohol dependency. Mayo Clinic health letter (English ed.) 20050401
Acamprosate (Campral) for alcoholism. Connecticut medicine 20050401
Predictors of acamprosate efficacy: results from a pooled analysis of seven European trials including 1485 alcohol-dependent patients. Psychopharmacology 20050301
Effect of acamprosate on neonatal excitotoxic cortical lesions in in utero alcohol-exposed hamsters. Neuroscience letters 20050210
Anti-craving drugs acamprosate and naloxone do not reduce expression of morphine conditioned place preference in isolated and group-housed rats. Neuroscience letters 20050210
Review: acamprosate and naltrexone are safe and effective but have low compliance rates for people with alcohol dependence. Evidence-based mental health 20050201
Opioid antagonists for alcohol dependence. The Cochrane database of systematic reviews 20050125
Acamprosate campral for alcoholism. The Medical letter on drugs and therapeutics 20050103
Buprenorphine and a CRF1 antagonist block the acquisition of opiate withdrawal-induced conditioned place aversion in rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20050101
The clock gene Per2 influences the glutamatergic system and modulates alcohol consumption. Nature medicine 20050101
New drugs: acamprosate calcium and solifenacin succinate. Journal of the American Pharmacists Association : JAPhA 20050101
Pharmacological relapse prevention of alcoholism: clinical predictors of outcome. European addiction research 20050101
Pharmacokinetics, safety, and tolerability of a depot formulation of naltrexone in alcoholics: an open-label trial. BMC psychiatry 20050101
Effect of the combined administration of ethanol and acamprosate on rabbit EEG. Pharmacological reports : PR 20050101
Effect of community nurse follow-up when treating alcohol dependence with acamprosate. Alcohol and alcoholism (Oxford, Oxfordshire) 20050101
Acamprosate: a review of its use in the maintenance of abstinence in patients with alcohol dependence. CNS drugs 20050101
A critical review of pharmacoeconomic studies of acamprosate. Alcohol and alcoholism (Oxford, Oxfordshire) 20050101
Neuroprotective and abstinence-promoting effects of acamprosate: elucidating the mechanism of action. CNS drugs 20050101
An open randomized study comparing disulfiram and acamprosate in the treatment of alcohol dependence. Alcohol and alcoholism (Oxford, Oxfordshire) 20050101
Taurine analogues; a new class of therapeutics: retrospect and prospects. Current medicinal chemistry 20050101
Clinical characterization of use of acamprosate and naltrexone: data from an addiction center in India. The American journal on addictions 20050101
Pharmacotherapy of alcohol use disorders. Substance use & misuse 20050101
Therapy and supportive care of alcoholics: guidelines for practitioners. Digestive diseases (Basel, Switzerland) 20050101
Tinnitus treatment with acamprosate: double-blind study. Brazilian journal of otorhinolaryngology 20050101
Pharmacotherapy, pharmacogenomics, and the future of alcohol dependence treatment, Part 2. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20041115
Pharmacotherapy, pharmacogenomics, and the future of alcohol dependence treatment, part 1. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20041101
Effect of neramexane on ethanol dependence and reinforcement. European journal of pharmacology 20041025
Recent advances in the pharmacotherapy of alcoholism. Current psychiatry reports 20041001
Assessing the efficacy of medical treatments for alcohol use disorders. Expert opinion on pharmacotherapy 20041001
The mosaic of addiction. The American journal of psychiatry 20041001
Ask the doctor. I need to quit drinking, but don't think I can do it on my own. Can I use a drug like Antabuse even though I have heart disease? Harvard heart letter : from Harvard Medical School 20041001
An overview of the development of medications including novel anticonvulsants for the treatment of alcohol dependence. Expert opinion on pharmacotherapy 20040901
Imbalance between neuroexcitatory and neuroinhibitory amino acids causes craving for ethanol. Addictive behaviors 20040901
Rats on the grog: novel pharmacotherapies for alcohol craving. Addictive behaviors 20040901
Assessment and modulation of acamprosate intestinal absorption: comparative studies using in situ, in vitro (CACO-2 cell monolayers) and in vivo models. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20040801
Biphasic effect of acamprosate on NMDA but not on GABAA receptors in spontaneous rhythmic activity from the isolated neonatal rat respiratory network. Neuropharmacology 20040701
Efficacy and safety of naltrexone and acamprosate in the treatment of alcohol dependence: a systematic review. Addiction (Abingdon, England) 20040701
Synthesis and assessment of [11C]acetylhomotaurine as an imaging agent for the study of the pharmacodynamic properties of acamprosate by positron emission tomography. Nuclear medicine and biology 20040701
The NMDA receptor channel blocker memantine and opioid receptor antagonist naltrexone inhibit the saccharin deprivation effect in rats. Behavioural pharmacology 20040701
Alcohol effects during acamprosate treatment: a dose-response study in humans. Alcoholism, clinical and experimental research 20040701
Hypothalamic-pituitary-adrenal system regulation in recently detoxified alcoholics is not altered by one week of treatment with acamprosate. Pharmacopsychiatry 20040501
[The pharmacologic treatment of the alcohol dependence]. Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) 20040501
Effect of the combination of naltrexone and acamprosate on alcohol intake in mice. Psychiatry and clinical neurosciences 20040201
Prevention of relapse to addiction: information for the practitioner. Texas medicine 20040201
Neurochemical changes of the extracellular concentrations of glutamate and aspartate in the nucleus accumbens of rats after chronic administration of morphine. European journal of pharmacology 20040112
NR2B subunit selective NMDA antagonists inhibit neurotoxic effect of alcohol-withdrawal in primary cultures of rat cortical neurones. Neurochemistry international 20040101
The efficacy of acamprosate in the maintenance of abstinence in alcohol-dependent individuals: results of a meta-analysis. Alcoholism, clinical and experimental research 20040101
Improvement in quality of life after treatment for alcohol dependence with acamprosate and psychosocial support. Alcoholism, clinical and experimental research 20040101
Acamprosate in alcohol dependence: a randomized controlled efficacy study in a standard clinical setting. Journal of studies on alcohol 20040101
A comparison of two intensities of psychosocial intervention for alcohol dependent patients treated with acamprosate. Alcohol and alcoholism (Oxford, Oxfordshire) 20040101
Pharmacodynamic effects of acamprosate on markers of cerebral function in alcohol-dependent subjects administered as pretreatment and during alcohol abstinence. Neuropsychobiology 20040101
Pharmacotherapy of alcohol dependence: a review of the clinical data. CNS drugs 20040101
A pragmatic trial of acamprosate in the treatment of alcohol dependence in primary care. Alcohol and alcoholism (Oxford, Oxfordshire) 20040101
Combined therapy: what does acamprosate and naltrexone combination tell us? Alcohol and alcoholism (Oxford, Oxfordshire) 20040101
Pragmatic trials and the ARES study. Alcohol and alcoholism (Oxford, Oxfordshire) 20040101
New drug to treat alcoholism. FDA consumer 20040101
Acamprosate involvement in triacylglycerol hydrolysis and transacylation with cholesterol in chronically ethanol-drinking rats. Journal of basic and clinical physiology and pharmacology 20040101
Acamprosate and naltrexone treatment for alcohol dependence: an evidence-based risk-benefits assessment. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20031201
Does acamprosate improve reduction of drinking as well as aiding abstinence? Journal of psychopharmacology (Oxford, England) 20031201
[Acamprosate--new preclinical research aspects]. MMW Fortschritte der Medizin 20031009
[Advances in the treatment of alcohol dependence: pharmacological relapse prevention]. MMW Fortschritte der Medizin 20031009
Caroverine inhibits the conditioned place aversion induced by naloxone-precipitated morphine withdrawal in rats. Neuroscience letters 20031002
Acamprosate blocks the increase in dopamine extracellular levels in nucleus accumbens evoked by chemical stimulation of the ventral hippocampus. Naunyn-Schmiedeberg's archives of pharmacology 20031001
[Psychosocial treatment plus drug prophylaxis. Fewer recurrences after alcohol withdrawal]. MMW Fortschritte der Medizin 20030904
Efficacy of acamprosate in the treatment of alcohol-dependent outpatients. Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) 20030901
New pharmacotherapies for alcohol dependence: are they being used and what do they cost? The Medical journal of Australia 20030818
Effects of naltrexone alone and in combination with acamprosate on the alcohol deprivation effect in rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20030801
The effect of acamprosate on the development of morphine-induced behavioral sensitization in rats. Behavioural pharmacology 20030701
Testing combined pharmacotherapies and behavioral interventions in alcohol dependence: rationale and methods. Alcoholism, clinical and experimental research 20030701
Testing combined pharmacotherapies and behavioral interventions for alcohol dependence (the COMBINE study): a pilot feasibility study. Alcoholism, clinical and experimental research 20030701
[The role of the glutamatergic system in alcohol addiction]. Fortschritte der Neurologie-Psychiatrie 20030701
Acamprosate and its efficacy in treating alcohol dependent adolescents. European child & adolescent psychiatry 20030601
Acamprosate does not induce a conditioned place preference and reveals no state-dependent effects in this paradigm. Progress in neuro-psychopharmacology & biological psychiatry 20030601
Dose-ranging kinetics and behavioral pharmacology of naltrexone and acamprosate, both alone and combined, in alcohol-dependent subjects. Journal of clinical psychopharmacology 20030601
A pilot study on the effects of treatment with acamprosate on craving for alcohol in alcohol-dependent patients. Addiction biology 20030601
Alcohol, nicotine, caffeine, and mental disorders. Dialogues in clinical neuroscience 20030601
[Preventing recurrence after alcohol withdrawal treatment with drugs. Reducing the drive to drink]. MMW Fortschritte der Medizin 20030508
Physicians' opinions about medications to treat alcoholism. Addiction (Abingdon, England) 20030501
Cost-effectiveness of adjuvant treatment with acamprosate in maintaining abstinence in alcohol dependent patients. European addiction research 20030401
Effects of acamprosate on excitatory amino acids during multiple ethanol withdrawal periods. Alcoholism, clinical and experimental research 20030301
Local acamprosate modulates dopamine release in the rat nucleus accumbens through NMDA receptors: an in vivo microdialysis study. Naunyn-Schmiedeberg's archives of pharmacology 20030201
[Deficits in preventing recurrence in alcoholic patients. Withdrawal--and immediately back to the bottle]. MMW Fortschritte der Medizin 20030116
Comparing and combining naltrexone and acamprosate in relapse prevention of alcoholism: a double-blind, placebo-controlled study. Archives of general psychiatry 20030101
The anti-relapse compound acamprosate inhibits the development of a conditioned place preference to ethanol and cocaine but not morphine. British journal of pharmacology 20030101
Acamprosate in Korean alcohol-dependent patients: a multi-centre, randomized, double-blind, placebo-controlled study. Alcohol and alcoholism (Oxford, Oxfordshire) 20030101
Acamprosate. Recent developments in alcoholism : an official publication of the American Medical Society on Alcoholism, the Research Society on Alcoholism, and the National Council on Alcoholism 20030101
Acamprosate for the adjunctive treatment of alcohol dependence. The Annals of pharmacotherapy 20030101
Research advances in the understanding and treatment of addiction. The American journal on addictions 20030101
The anti-craving taurine derivative acamprosate: failure to extinguish morphine conditioned place preference. Advances in experimental medicine and biology 20030101
Pharmacology of acamprosate: an overview. CNS drug reviews 20030101
[Acamprosate (Aotal): could adverse effects upset the treatment of alcohol dependence?]. Therapie 20030101
[Neural basis of alcohol dependence]. Duodecim; laaketieteellinen aikakauskirja 20030101
[Drug therapy of alcohol dependence--a critical review]. Duodecim; laaketieteellinen aikakauskirja 20030101
Pharmacological mechanisms of naltrexone and acamprosate in the prevention of relapse in alcohol dependence. The American journal on addictions 20030101
Current pharmacotherapies of alcoholism: a U.S. perspective. The American journal on addictions 20030101
Use of acamprosate and opioid antagonists in the treatment of alcohol dependence: a European perspective. The American journal on addictions 20030101
Acamprosate inhibits the binding and neurotoxic effects of trans-ACPD, suggesting a novel site of action at metabotropic glutamate receptors. Alcoholism, clinical and experimental research 20021201
Alcohol misuse and dependence. Assessment and management. Australian family physician 20021201
Human models as tools in the development of psychotropic drugs. Dialogues in clinical neuroscience 20021201
Cognitive behavioural therapy combined with the relapse-prevention medication acamprosate: are short-term treatment outcomes for alcohol dependence improved? The Australian and New Zealand journal of psychiatry 20021001
Disposition of acamprosate in the rat: influence of probenecid. Biopharmaceutics & drug disposition 20021001
A review of chemical agents in the pharmacotherapy of addiction. Current medicinal chemistry 20021001
Acamprosate reduces context-dependent ethanol effects. Psychopharmacology 20021001
A pharmacokinetic and pharmacodynamic drug interaction study of acamprosate and naltrexone. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20021001
Acamprosate, MK-801, and ifenprodil inhibit neurotoxicity and calcium entry induced by ethanol withdrawal in organotypic slice cultures from neonatal rat hippocampus. Alcoholism, clinical and experimental research 20021001
The European NEAT program: an integrated approach using acamprosate and psychosocial support for the prevention of relapse in alcohol-dependent patients with a statistical modeling of therapy success prediction. Alcoholism, clinical and experimental research 20021001
New pharmacotherapies for alcohol dependence. The Medical journal of Australia 20020715
Acamprosate decreases the induction of tolerance and physical dependence in morphine-treated mice. European journal of pharmacology 20020607
Effects of acamprosate and some polyamine site ligands of NMDA receptor on short-term memory in rats. European journal of pharmacology 20020524
Acamprosate has no effect on NMDA-induced toxicity but reduces toxicity induced by spermidine or by changing the medium in organotypic hippocampal slice cultures from rat. Alcoholism, clinical and experimental research 20020501
[Long-term treatment of alcohol dependance]. Gastroenterologie clinique et biologique 20020501
[Acamprosate and psychosocial intervention. An integrative treatment approach for prevention of alcohol dependent patients in Switzerland]. Praxis 20020424
Drug treatments for alcoholism. The Harvard mental health letter 20020401
Potential neuroprotective effects of acamprosate. Alcoholism, clinical and experimental research 20020401
Mesa Grande: a methodological analysis of clinical trials of treatments for alcohol use disorders. Addiction (Abingdon, England) 20020301
Effects of acute acamprosate and homotaurine on ethanol intake and ethanol-stimulated mesolimbic dopamine release. European journal of pharmacology 20020215
Central nervous system mechanisms in alcohol relapse. Alcoholism, clinical and experimental research 20020201
Long-lasting increase in voluntary ethanol consumption and transcriptional regulation in the rat brain after intermittent exposure to alcohol. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20020101
Use of acamprosate and different kinds of psychosocial support in relapse prevention of alcoholism. Results from a non-blind, multicentre study. Drugs in R&D 20020101
Acamprosate. Drugs in R&D 20020101
Acceptability and availability of pharmacological interventions for substance misuse by British NHS treatment services. Addiction (Abingdon, England) 20020101
Opioid antagonists for alcohol dependence. The Cochrane database of systematic reviews 20020101
Does psychosocial treatment enhance the efficacy of acamprosate in patients with alcohol problems? Alcohol and alcoholism (Oxford, Oxfordshire) 20020101
Relapse prevention and maintaining abstinence in older adults with alcohol-use disorders. Drugs & aging 20020101
Interactions between taurine and ethanol in the central nervous system. Amino acids 20020101
Pharmacological approaches to the treatment of excessive drinking and alcohol dependence. Expert review of neurotherapeutics 20020101
Addiction medicine for the primary care physician. The Journal of the Oklahoma State Medical Association 20011101
Effects of acamprosate on sensitization to the locomotor-stimulant effects of alcohol in mice selectively bred for high and low alcohol preference. Behavioural pharmacology 20011101
Acamprosate is neuroprotective against glutamate-induced excitotoxicity when enhanced by ethanol withdrawal in neocortical cultures of fetal rat brain. Alcoholism, clinical and experimental research 20010901
Efficacy of naltrexone and acamprosate for alcoholism treatment: a meta-analysis. Alcoholism, clinical and experimental research 20010901
[Adjuvant drug treatment of alcoholism with acamprosate: between sectoral budgets and disease management]. Deutsche medizinische Wochenschrift (1946) 20010817
Does the alcoholic's remedy come in a pill? Behavioral healthcare tomorrow 20010801
Combined behavioral and pharmacologic treatments of alcoholism. American clinical laboratory 20010701
[Therapeutic strategies and help in chronic alcoholism]. Gesundheitswesen (Bundesverband der Arzte des Offentlichen Gesundheitsdienstes (Germany)) 20010601
The anti-craving compound acamprosate acts as a weak NMDA-receptor antagonist, but modulates NMDA-receptor subunit expression similar to memantine and MK-801. Neuropharmacology 20010501
Pharmacological relapse prevention in alcohol dependence: from animal models to clinical trials. Alcoholism, clinical and experimental research 20010501
Role of polyamines and NMDA receptors in ethanol dependence and withdrawal. Alcoholism, clinical and experimental research 20010501
Mechanisms of alcohol-nicotine interactions: alcoholics versus smokers. Alcoholism, clinical and experimental research 20010501
Naltrexone and acamprosate. Using new drugs for alcohol dependence. Australian family physician 20010501
Effects of acamprosate on ethanol-seeking and self-administration in the rat. Alcoholism, clinical and experimental research 20010301
Can this pill stop you from hitting the bottle? Newsweek 20010212
Effect of acamprosate and naltrexone, alone or in combination, on ethanol consumption. Alcohol (Fayetteville, N.Y.) 20010201
The European acamprosate trials: conclusions for research and therapy. Journal of biomedical science 20010101
Neurotoxic effect of acamprosate, n-acetyl-homotaurine, in cultured neurons. Journal of biomedical science 20010101
Theories of drug craving, ancient and modern. Addiction (Abingdon, England) 20010101
Liver diseases by alcohol and hepatitis C: early detection and new insights in pathogenesis lead to improved treatment. The American journal on addictions 20010101
New developments in the pharmacotherapy of alcohol dependence. The American journal on addictions 20010101
Acamprosate during and after acute alcohol withdrawal: a double-blind placebo-controlled study in Spain. Alcohol and alcoholism (Oxford, Oxfordshire) 20010101
Naltrexone versus acamprosate: one year follow-up of alcohol dependence treatment. Alcohol and alcoholism (Oxford, Oxfordshire) 20010101
Pharmacologic approaches to the management of alcoholism. The Journal of clinical psychiatry 20010101
Treatment of alcohol-dependent outpatients with acamprosate: a clinical review. The Journal of clinical psychiatry 20010101
Effects of acamprosate and scopolamine on the working memory of rats in a three-panel runway task. Journal of basic and clinical physiology and pharmacology 20010101
Drug addiction. Part III. Pharmacotherapy of addiction. Polish journal of pharmacology 20010101
[The neuroprotective effect of the glutamate antagonist acamprosate following experimental cerebral ischemia. A study with the lipid peroxidase inhibitor u-101033e]. Der Anaesthesist 20000901
The role of glutamatergic neurotransmission in the pathophysiology of alcoholism. Annual review of medicine 19980101
Acamprosate. A review of its pharmacology and clinical potential in the management of alcohol dependence after detoxification. Drugs 19970601
Ability of calcium bis acetyl homotaurine, a GABA agonist, to prevent relapse in weaned alcoholics. Lancet (London, England) 19850504
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