Home Other Building Blocks 1,8-Naphthyridin-2-amine,5,6,7-trimethyl-

1,8-Naphthyridin-2-amine,5,6,7-trimethyl-

CAS No.:
69587-84-4
Catalog Number:
AG005K40
Molecular Formula:
C11H13N3
Molecular Weight:
187.2410
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Product Description
Catalog Number:
AG005K40
Chemical Name:
1,8-Naphthyridin-2-amine,5,6,7-trimethyl-
CAS Number:
69587-84-4
Molecular Formula:
C11H13N3
Molecular Weight:
187.2410
MDL Number:
MFCD08262809
IUPAC Name:
5,6,7-trimethyl-1,8-naphthyridin-2-amine
InChI:
InChI=1S/C11H13N3/c1-6-7(2)9-4-5-10(12)14-11(9)13-8(6)3/h4-5H,1-3H3,(H2,12,13,14)
InChI Key:
ZZZNDZVOGHOUET-UHFFFAOYSA-N
SMILES:
Nc1ccc2c(n1)nc(c(c2C)C)C
Properties
Complexity:
207  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
187.111g/mol
Formal Charge:
0
Heavy Atom Count:
14  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
187.246g/mol
Monoisotopic Mass:
187.111g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
51.8A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
2.2  
Literature
Title Journal
Label-free fluorescence detection of the depurination activity of ribosome inactivating protein toxins. Chemical communications (Cambridge, England) 20120114
Label-free molecular beacon system based on DNAs containing abasic sites and fluorescent ligands that bind abasic sites. Chemistry (Weinheim an der Bergstrasse, Germany) 20111004
Fluorescent trimethyl-substituted naphthyridine as a ligand for C-C mismatch detection in CCG trinucleotide repeats. Chemical communications (Cambridge, England) 20110528
Label-free fluorescent molecular beacon based on a small fluorescent molecule non-covalently bound to the intentional gap site in the stem moiety. Talanta 20101215
Effect of substituents of alloxazine derivatives on the selectivity and affinity for adenine in AP-site-containing DNA duplexes. Organic & biomolecular chemistry 20101107
Label-free fluorescent functional DNA sensors using unmodified DNA: a vacant site approach. Analytical chemistry 20100515
Label-free aptamer-based sensor using abasic site-containing DNA and a nucleobase-specific fluorescent ligand. Chemical communications (Cambridge, England) 20091114
Abasic site-containing DNAzyme and aptamer for label-free fluorescent detection of Pb(2+) and adenosine with high sensitivity, selectivity, and tunable dynamic range. Journal of the American Chemical Society 20091028
Effect of an alkyl amino group on the binding of 1,8-naphthyridines to AP site-containing DNA duplexes. Nucleic acids symposium series (2004) 20080101
Competitive binding of small ligands to nucleobases in AP site-containing DNA duplexes. Nucleic acids symposium series (2004) 20080101
Strong binding of naphthyridine derivatives to cytosine in an AP site-containing DNA duplex and their application to fluorescence detection of single nucleotide polymorphisms. Nucleic acids symposium series (2004) 20070101
Properties