Home Carboxys ethyl 12-fluoro-8-methyl-9-oxo-2,4,8-triazatricyclo[8.4.0.0^{2,6}]tetradeca-1(10),3,5,11,13-pentaene-5-carboxylate

ethyl 12-fluoro-8-methyl-9-oxo-2,4,8-triazatricyclo[8.4.0.0^{2,6}]tetradeca-1(10),3,5,11,13-pentaene-5-carboxylate

CAS No.:
78755-81-4
Catalog Number:
AG005JF1
Molecular Formula:
C15H14FN3O3
Molecular Weight:
303.2884
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5mg
99%(HPLC)powder
In Stock USA
United States
$54
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10mg
99%(HPLC)powder
In Stock USA
United States
$61
- +
100mg
98%
In Stock USA
United States
$82
- +
250mg
98%
In Stock USA
United States
$159
- +
1g
98%
In Stock USA
United States
$435
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5g
98%
In Stock USA
United States
$1500
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Product Description
Catalog Number:
AG005JF1
Chemical Name:
ethyl 12-fluoro-8-methyl-9-oxo-2,4,8-triazatricyclo[8.4.0.0^{2,6}]tetradeca-1(10),3,5,11,13-pentaene-5-carboxylate
CAS Number:
78755-81-4
Molecular Formula:
C15H14FN3O3
Molecular Weight:
303.2884
MDL Number:
MFCD00242764
IUPAC Name:
ethyl 8-fluoro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate
InChI:
InChI=1S/C15H14FN3O3/c1-3-22-15(21)13-12-7-18(2)14(20)10-6-9(16)4-5-11(10)19(12)8-17-13/h4-6,8H,3,7H2,1-2H3
InChI Key:
OFBIFZUFASYYRE-UHFFFAOYSA-N
SMILES:
CCOC(=O)c1ncn2c1CN(C)C(=O)c1c2ccc(c1)F
EC Number:
616-650-9
UNII:
40P7XK9392
NSC Number:
759193
Properties
Complexity:
461  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
303.102g/mol
Formal Charge:
0
Heavy Atom Count:
22  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
303.293g/mol
Monoisotopic Mass:
303.102g/mol
Rotatable Bond Count:
3  
Topological Polar Surface Area:
64.4A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
1  
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Hesperidin produces antinociceptive response and synergistic interaction with ketorolac in an arthritic gout-type pain in rats. Pharmacology, biochemistry, and behavior 20110201
Use of bispectral index monitoring for a patient with hepatic encephalopathy requiring living donor liver transplantation: a case report. Journal of anesthesia 20110201
Mechanism of emergence agitation induced by sevoflurane anesthesia. Korean journal of anesthesiology 20110201
Chronic benzodiazepine treatment does not alter interactions between positive GABA(A) modulators and flumazenil or pentylenetetrazole in monkeys. Behavioural pharmacology 20110201
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Recovery from sedation with remifentanil and propofol, compared with morphine and midazolam, for reduction in anterior shoulder dislocation. Emergency medicine journal : EMJ 20110101
Allosteric modulators induce distinct movements at the GABA-binding site interface of the GABA-A receptor. Neuropharmacology 20110101
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The fallacy of a lifesaving sublingual injection of flumazenil. Anesthesia progress 20110101
Lorazepam-induced prolonged apnea after ECT-induced prolonged seizure. Indian journal of psychiatry 20110101
Anxiolytic-like effects of 4-O-methylhonokiol isolated from Magnolia officinalis through enhancement of GABAergic transmission and chloride influx. Journal of medicinal food 20110101
Influence of a brief episode of anesthesia during the induction of experimental brain trauma on secondary brain damage and inflammation. PloS one 20110101
Is attentional blink a byproduct of neocortical attractors? Frontiers in computational neuroscience 20110101
Management of an oral ingestion of transdermal fentanyl patches: a case report and literature review. Case reports in medicine 20110101
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Aerosolized BC-819 inhibits primary but not secondary lung cancer growth. PloS one 20110101
Midazolam activates the intrinsic pathway of apoptosis independent of benzodiazepine and death receptor signaling. Regional anesthesia and pain medicine 20110101
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SPECT imaging of GABA(A)/benzodiazepine receptors and cerebral perfusion in mild cognitive impairment. European journal of nuclear medicine and molecular imaging 20100601
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Extending submarine crew survival by reducing CO2 production with quickly reversible sedation. Aviation, space, and environmental medicine 20100601
The routine use of a flumazenil infusion following percutaneous endoscopic gastrostomy placement to reduce early post-procedure mortality. The journal of the Royal College of Physicians of Edinburgh 20100601
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In vivo imaging of neuroinflammation: a comparative study between [(18)F]PBR111, [ (11)C]CLINME and [ (11)C]PK11195 in an acute rodent model. European journal of nuclear medicine and molecular imaging 20100501
Pharmacological characterization of the discriminative stimulus of inhaled 1,1,1-trichloroethane. The Journal of pharmacology and experimental therapeutics 20100501
Epileptic negative myoclonus: a combined study of EEG and [123I]iomazenil (123I-IMZ) single photon emission computed tomography indicating involvement of medial frontal area. Epilepsy research 20100501
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Evaluation of behavioral and pharmacological effects of Hedyosmum brasiliense and isolated sesquiterpene lactones in rodents. Journal of ethnopharmacology 20100302
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Colonoscopy and sedation in Romania: early experience using a balanced propofol regimen. Journal of gastrointestinal and liver diseases : JGLD 20100301
HPLC-based activity profiling: discovery of piperine as a positive GABA(A) receptor modulator targeting a benzodiazepine-independent binding site. Journal of natural products 20100226
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Discriminative stimulus effects of L-838,417 (7-tert-butyl-3-(2,5-difluoro-phenyl)-6-(2-methyl-2H-[1,2,4]triazol-3-ylmethoxy)-[1,2,4]triazolo[4,3-b]pyridazine): role of GABA(A) receptor subtypes. Neuropharmacology 20100201
The effect of midazolam on mouse Leydig cell steroidogenesis and apoptosis. Toxicology letters 20100201
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Intranasal flumazenil and naloxone to reverse over-sedation in a child undergoing dental restorations: comment. Paediatric anaesthesia 20100101
Interesting image. I-123 iomazenil SPECT imaging in a patient with hemispheric brain damage due to cerebral ischemia during carotid endarterectomy. Clinical nuclear medicine 20100101
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Sinapic acid attenuates kainic acid-induced hippocampal neuronal damage in mice. Neuropharmacology 20100101
Pharmacology of sedation agents and reversal agents. Digestion 20100101
Ability to reverse deeper levels of unintended sedation. Digestion 20100101
Epilepsy: The future scenario. Annals of Indian Academy of Neurology 20100101
Sedation and anesthesia options for pediatric patients in the radiation oncology suite. International journal of pediatrics 20100101
Glasgow Coma Scale in acute poisonings before and after use of antidote in patients with history of use of psychotropic agents. Srpski arhiv za celokupno lekarstvo 20100101
Continuous cervical epidural analgesia for Isshiki type - I thyroplasty. Indian journal of anaesthesia 20100101
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Procedural sedation analgesia. Saudi journal of anaesthesia 20100101
Epilepsy surgery: recommendations for India. Annals of Indian Academy of Neurology 20100101
Distinct α subunit variations of the hypothalamic GABAA receptor triplets (αβγ) are linked to hibernating state in hamsters. BMC neuroscience 20100101
Local erythropoietin and endothelial progenitor cells improve regional cardiac function in acute myocardial infarction. BMC cardiovascular disorders 20100101
Paradoxical reaction to midazolam reversed with flumazenil. Journal of emergencies, trauma, and shock 20100101
Pharmacological intervention: Reversal of sedation. Gastroenterology nursing : the official journal of the Society of Gastroenterology Nurses and Associates 20100101
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Effect of soybean supplementation on the memory of alprazolam-induced amnesic mice. Journal of pharmacy & bioallied sciences 20100101
Ocimum sanctum Linn. A reservoir plant for therapeutic applications: An overview. Pharmacognosy reviews 20100101
Effects of isopulegol on pentylenetetrazol-induced convulsions in mice: possible involvement of GABAergic system and antioxidant activity. Fitoterapia 20091201
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Anxiolytic effects of L-theanine--a component of green tea--when combined with midazolam, in the male Sprague-Dawley rat. AANA journal 20091201
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In vitro and in vivo properties of 3-tert-butyl-7-(5-methylisoxazol-3-yl)-2-(1-methyl-1H-1,2,4-triazol-5-ylmethoxy)-pyrazolo[1,5-d]-[1,2,4]triazine (MRK-016), a GABAA receptor alpha5 subtype-selective inverse agonist. The Journal of pharmacology and experimental therapeutics 20091101
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Improved work-up procedure for the production of [(18)F]flumazenil and first results of its use with a high-resolution research tomograph in human stroke. Nuclear medicine and biology 20091001
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Neonatal phencyclidine treatment in mice induces behavioral, histological and neurochemical abnormalities in adulthood. Biological & pharmaceutical bulletin 20090901
Synthesis, in vivo evaluation, and molecular modeling studies of new pyrazolo[5,1-c][1,2,4]benzotriazine 5-oxide derivatives. Identification of a bifunctional hydrogen bond area related to the inverse agonism. Journal of medicinal chemistry 20090813
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Population patch-clamp electrophysiology analysis of recombinant GABAA alpha1beta3gamma2 channels expressed in HEK-293 cells. Journal of biomolecular screening 20090801
Efficacy of a combination of flumazenil and gabapentin in the treatment of alcohol dependence: relationship to alcohol withdrawal symptoms. Journal of clinical psychopharmacology 20090801
Intranasal flumazenil and naloxone to reverse over-sedation in a child undergoing dental restorations. Paediatric anaesthesia 20090801
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The role of flumazenil in the treatment of benzodiazepine dependence: physiological and psychological profiles. Journal of psychopharmacology (Oxford, England) 20090601
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Development of microwave-based automated nucleophilic [(18)F]fluorination system and its application to the production of [(18)F]flumazenil. Nuclear medicine and biology 20090501
A novel operant conflict procedure using incrementing shock intensities to assess the anxiolytic and anxiogenic effects of drugs. Behavioural pharmacology 20090501
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[18F]flumazenil binding to central benzodiazepine receptor studies by PET--quantitative analysis and comparisons with [11C]flumazenil. NeuroImage 20090415
Kinetic modelling of [11C]flumazenil using data-driven methods. European journal of nuclear medicine and molecular imaging 20090401
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The effects of benzodiazepines on urotensin II-stimulated norepinephrine release from rat cerebrocortical slices. Anesthesia and analgesia 20090401
Kaempferol from the leaves of Apocynum venetum possesses anxiolytic activities in the elevated plus maze test in mice. Phytomedicine : international journal of phytotherapy and phytopharmacology 20090401
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The antinociceptive effects and pharmacological properties of JM-1232(-): a novel isoindoline derivative. Anesthesia and analgesia 20090301
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Tiagabine increases [11C]flumazenil binding in cortical brain regions in healthy control subjects. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20090201
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Postoperative cortical neural loss associated with cerebral hyperperfusion and cognitive impairment after carotid endarterectomy: 123I-iomazenil SPECT study. Stroke 20090201
Genuine antihyperalgesia by systemic diazepam revealed by experiments in GABAA receptor point-mutated mice. Pain 20090201
Effect of intravenous flumazenil on oral midazolam pharmacokinetics and pharmacodynamics for use as a cytochrome P450 3A probe. International journal of clinical pharmacology and therapeutics 20090201
Investigation of the anxiolytic effects of luteolin, a lemon balm flavonoid in the male Sprague-Dawley rat. AANA journal 20090201
[Pharmacodynamic and pharmacokinetic effects of flumazenil and theophylline application in rats acutely intoxicated by diazepam]. Vojnosanitetski pregled 20090201
Long-lasting modulation of glutamatergic transmission in VTA dopamine neurons after a single dose of benzodiazepine agonists. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20090101
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Accuracy of 3-dimensional reconstruction algorithms for the high-resolution research tomograph. Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20090101
Midazolam inhibits tumor necrosis factor-alpha-induced endothelial activation: involvement of the peripheral benzodiazepine receptor. Anesthesiology 20090101
In vivo saturation binding of GABA-A receptor ligands to estimate receptor occupancy using liquid chromatography/tandem mass spectrometry. Biopharmaceutics & drug disposition 20090101
Pharmacology of ramelteon, a selective MT1/MT2 receptor agonist: a novel therapeutic drug for sleep disorders. CNS neuroscience & therapeutics 20090101
Review of knee arthroscopy performed under local anesthesia. Sports medicine, arthroscopy, rehabilitation, therapy & technology : SMARTT 20090101
Expression levels of the alpha4 subunit of the GABA(A) receptor in differentiated neuroblastoma cells are correlated with GABA-gated current. Neuropharmacology 20090101
Management of the critically poisoned patient. Scandinavian journal of trauma, resuscitation and emergency medicine 20090101
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Studying Cerebellar Circuits by Remote Control of Selected Neuronal Types with GABA(A) Receptors. Frontiers in molecular neuroscience 20090101
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The localization of inhibitory neurotransmitter receptors on dopaminergic neurons of the human substantia nigra. Journal of neural transmission. Supplementum 20090101
Image derived input functions for dynamic High Resolution Research Tomograph PET brain studies. NeuroImage 20081201
Comparison of the novel subtype-selective GABAA receptor-positive allosteric modulator NS11394 [3'-[5-(1-hydroxy-1-methyl-ethyl)-benzoimidazol-1-yl]-biphenyl-2-carbonitrile] with diazepam, zolpidem, bretazenil, and gaboxadol in rat models of inflammatory and neuropathic pain. The Journal of pharmacology and experimental therapeutics 20081201
Anxiolytic activity of a phytochemically characterized Passiflora incarnata extract is mediated via the GABAergic system. Planta medica 20081201
Doctors' knowledge of the appropriate use and route of administration of antidotes in the management of recreational drug toxicity. Emergency medicine journal : EMJ 20081201
A high-throughput functional assay for characterization of gamma-aminobutyric acid(A) channel modulators using cryopreserved transiently transfected cells. Assay and drug development technologies 20081201
Structural requirements for eszopiclone and zolpidem binding to the gamma-aminobutyric acid type-A (GABAA) receptor are different. Journal of medicinal chemistry 20081127
Anticonvulsant activity of Carissa edulis (Vahl) (Apocynaceae) root bark extract. Journal of ethnopharmacology 20081120
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Participation of the GABA/benzodiazepine receptor and the NO-cyclicGMP pathway in the 'antinociceptive-like effects' of diazepam. Pharmacology, biochemistry, and behavior 20081101
Effects of FG7142 and immobilization stress on the gene expression in the neocortex of mice. Neuroscience research 20081101
Androgens with activity at estrogen receptor beta have anxiolytic and cognitive-enhancing effects in male rats and mice. Hormones and behavior 20081101
Utility of flumazenil in zopiclone overdose. Clinical toxicology (Philadelphia, Pa.) 20081101
Sleep deprivation therapy. Neuro endocrinology letters 20081101
Reduced midazolam clearance must be considered in prolonged coma. Anaesthesia and intensive care 20081101
Treatment of minimal hepatic encephalopathy. Hepatology research : the official journal of the Japan Society of Hepatology 20081101
[Functional imaging in Binswanger's disease]. Rinsho shinkeigaku = Clinical neurology 20081101
Possible GABAergic modulation in the protective effect of allopregnanolone on sleep deprivation-induced anxiety-like behavior and oxidative damage in mice. Methods and findings in experimental and clinical pharmacology 20081101
Antinociceptive property of intrathecal and intraperitoneal administration of a novel water-soluble isoindolin-1-one derivative, JM 1232 (-) in rats. European journal of pharmacology 20081031
S-ketamine and GABA-A-receptor interaction in humans: an exploratory study with I-123-iomazenil SPECT. Human psychopharmacology 20081001
Flavan-3-ol derivatives are positive modulators of GABA(A) receptors with higher efficacy for the alpha(2) subtype and anxiolytic action in mice. Neuropharmacology 20081001
Pharmacokinetics and clinical efficacy of midazolam in children with severe malaria and convulsions. British journal of clinical pharmacology 20081001
Altered cerebral gamma-aminobutyric acid type A-benzodiazepine receptor binding in panic disorder determined by [11C]flumazenil positron emission tomography. Archives of general psychiatry 20081001
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Anticonvulsant effect of a natural compound alpha,beta-epoxy-carvone and its action on the nerve excitability. Neuroscience letters 20080926
Intra-periaqueductal gray matter injections of midazolam fail to alter anxiety in plus-maze experienced mice. Brain research 20080922
6,3'-Dinitroflavone is a low efficacy modulator of GABA(A) receptors. European journal of pharmacology 20080904
11C-flumazenil positron emission tomography demonstrates reduction of both global and local cerebral benzodiazepine receptor binding in a patient with Stiff Person Syndrome. Journal of neurology 20080901
Selective activation of metabotropic G-protein-coupled glutamate 7 receptor elicits anxiolytic-like effects in mice by modulating GABAergic neurotransmission. Behavioural pharmacology 20080901
Comparison of PET and DW/PW-MRI in acute ischemic stroke. The Keio journal of medicine 20080901
Involvement of the GABA/benzodiazepine receptor in the axiolytic-like effect of nociceptin/orphanin FQ. European journal of pharmacology 20080820
Menthol shares general anesthetic activity and sites of action on the GABA(A) receptor with the intravenous agent, propofol. European journal of pharmacology 20080820
Ethyl 8-fluoro-6-(3-nitrophenyl)-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate as novel, highly potent, and safe antianxiety agent. Journal of medicinal chemistry 20080814
Inflammation-induced shift in the valence of spinal GABA-A receptor-mediated modulation of nociception in the adult rat. The journal of pain : official journal of the American Pain Society 20080801
GABA(A) signalling is involved in N/OFQ anxiolytic-like effects but not in nocistatin anxiogenic-like action as evaluated in the mouse elevated plus maze. Peptides 20080801
Chrysin induces hyperalgesia via the GABAA receptor in mice. Planta medica 20080801
Delayed-onset hepatic encephalopathy induced by zolpidem: a case report. Clinics (Sao Paulo, Brazil) 20080801
In vivo characterization and dynamic receptor occupancy imaging of TPA023B, an alpha 2/alpha 3/alpha 5 subtype selective gamma-aminobutyric acid-a partial agonist. Biological psychiatry 20080715
Selective influence on contextual memory: physiochemical properties associated with selectivity of benzodiazepine ligands at GABAA receptors containing the alpha5 subunit. Journal of medicinal chemistry 20080710
Individually monitoring ligand-induced changes in the structure of the GABAA receptor at benzodiazepine binding site and non-binding-site interfaces. Molecular pharmacology 20080701
The role of transcriptional and translational mechanisms in flumazenil-induced up-regulation of recombinant GABA(A) receptors. Neuroscience research 20080701
Effect of diazepam on the runway method using priming stimulation of intracranial self stimulation behavior. Journal of pharmacological sciences 20080701
[Patient awakening from anesthesia was re-sedated by administration of flumazenil]. Masui. The Japanese journal of anesthesiology 20080701
Adenosine receptor agonists attenuate the development of diazepam withdrawal-induced sensitization in mice. European journal of pharmacology 20080624
Midazolam inhibits cardiac nociception evoked by coronary artery occlusion in rats. European journal of anaesthesiology 20080601
Reversal of paradoxical excitement to diazepam sedation. Paediatric anaesthesia 20080601
Measurement of GABAA receptor binding in vivo with [11C]flumazenil: a test-retest study in healthy subjects. NeuroImage 20080601
Midazolam attenuates the antinociception induced by d-serine or morphine at the supraspinal level in rats. European journal of pharmacology 20080531
Reduced GABA neurotransmission underlies hyperalgesia induced by repeated forced swimming stress. Behavioural brain research 20080516
Measurement of the 11C-flumazenil binding in the visual cortex predicts the prognosis of hemianopia. Journal of the neurological sciences 20080515
Anticonvulsive effects of intracerebroventricular administration of rutin in rats. Progress in neuro-psychopharmacology & biological psychiatry 20080515
PWZ-029, a compound with moderate inverse agonist functional selectivity at GABA(A) receptors containing alpha5 subunits, improves passive, but not active, avoidance learning in rats. Brain research 20080507
Iatrogenic delirium and coma: a 'near miss'. Chest 20080501
Novel 3-aroylpyrazolo[5,1-c][1,2,4]benzotriazine 5-oxides 8-substituted, ligands at GABAA/benzodiazepine receptor complex: synthesis, pharmacological and molecular modeling studies. Bioorganic & medicinal chemistry 20080415
Pharmacological evaluation of [123I]-CLINDE: a radioiodinated imidazopyridine-3-acetamide for the study of peripheral benzodiazepine binding sites (PBBS). European journal of nuclear medicine and molecular imaging 20080401
Anticonvulsant and anxiolytic-like effects of compounds isolated from Polygala sabulosa (Polygalaceae) in rodents: in vitro and in vivo interactions with benzodiazepine binding sites. Psychopharmacology 20080401
Alternative psychosis and dysgraphia accompanied by forced normalization in a girl with occipital lobe epilepsy. Epilepsy & behavior : E&B 20080401
Protective effect of alprazolam against sleep deprivation-induced behavior alterations and oxidative damage in mice. Neuroscience research 20080401
Rectal Flumazenil can save the day. Paediatric anaesthesia 20080401
Short-term plasticity of central benzodiazepine receptors in status epilepticus: case report. Acta neurologica Scandinavica 20080401
[(11)C]flumazenil positron emission tomography analyses of brain gamma-aminobutyric acid type A receptors in Angelman syndrome. The Journal of pediatrics 20080401
Midazolam administration reverses thermal hyperalgesia and prevents gamma-aminobutyric acid transporter loss in a rodent model of neuropathic pain. Anesthesia and analgesia 20080401
Positron emission tomography and target-controlled infusion for precise modulation of brain drug concentration. Nuclear medicine and biology 20080401
Flumazenil in the treatment of dizziness and vegetative symptoms after intravenous infusion of paclitaxel. Onkologie 20080401
Repeated lipopolysaccharide (LPS) or cytokine treatments sensitize ethanol withdrawal-induced anxiety-like behavior. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20080301
Possible GABAergic modulation in the protective effect of zolpidem in acute hypoxic stress-induced behavior alterations and oxidative damage. Neurochemical research 20080301
Comparison of plasma input and reference tissue models for analysing [(11)C]flumazenil studies. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20080301
Decreased chronic-stage cortical 11C-flumazenil binding after focal ischemia-reperfusion in baboons: a marker of selective neuronal loss? Stroke 20080301
MRI-based correction for partial-volume effect improves detectability of intractable epileptogenic foci on 123I-iomazenil brain SPECT images. Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20080301
Treatment of methamphetamine dependence. Mayo Clinic proceedings 20080301
[Poisoning by liquid ecstasy (GHB) in hospital emergency departments of Barcelona: a 2-years study]. Medicina clinica 20080301
Epilepsy surgery: eligibility criteria and presurgical evaluation. Dialogues in clinical neuroscience 20080301
GABA(A) receptors in normal development and seizures: friends or foes? Current neuropharmacology 20080301
Role of neuroimaging in the presurgical evaluation of epilepsy. Journal of clinical neurology (Seoul, Korea) 20080301
Treatment with haloperidol and diazepam alters GABA(A) receptor density in the rat brain. Progress in neuro-psychopharmacology & biological psychiatry 20080215
The anxiolytic-like effect of the selective 5-HT6 receptor antagonist SB-399885: the impact of benzodiazepine receptors. European journal of pharmacology 20080212
Antagonistic effects of atipamezole, flumazenil and 4-aminopyridine against anaesthesia with medetomidine, midazolam and ketamine combination in cats. Journal of feline medicine and surgery 20080201
Partial volume corrected image derived input functions for dynamic PET brain studies: methodology and validation for [11C]flumazenil. NeuroImage 20080201
Modulation of synaptic GABAA receptor function by zolpidem in substantia nigra pars reticulata. Acta pharmacologica Sinica 20080201
Neuronal loss associated with cognitive performance in amyotrophic lateral sclerosis: an (11C)-flumazenil PET study. Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases 20080201
Investigation of the anxiolytic effects of linalool, a lavender extract, in the male Sprague-Dawley rat. AANA journal 20080201
Impact of attenuation correction strategies on the quantification of High Resolution Research Tomograph PET studies. Physics in medicine and biology 20080107
[11C]Flumazenil PET in temporal lobe epilepsy: do we need an arterial input function or kinetic modeling? Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20080101
Reduced GABAA benzodiazepine receptor binding in veterans with post-traumatic stress disorder. Molecular psychiatry 20080101
Comparative analysis of MR imaging, ictal SPECT and EEG in temporal lobe epilepsy: a prospective IAEA multi-center study. European journal of nuclear medicine and molecular imaging 20080101
Euphorbia hirta reverses chronic stress-induced anxiety and mediates its action through the GABA(A) receptor benzodiazepine receptor-Cl(-) channel complex. Journal of neural transmission (Vienna, Austria : 1996) 20080101
Xenon does not affect gamma-aminobutyric acid type A receptor binding in humans. Anesthesia and analgesia 20080101
Acute poisonings treated in hospitals in Oslo: a one-year prospective study (II): clinical outcome. Clinical toxicology (Philadelphia, Pa.) 20080101
Midazolam and other benzodiazepines. Handbook of experimental pharmacology 20080101
[123I iomazenil SPECT and identification of the epileptogenic tubers in patients with tuberous sclerosis]. No to hattatsu = Brain and development 20080101
Clinical review: Major consequences of illicit drug consumption. Critical care (London, England) 20080101
Molecular and diffusion tensor imaging of epileptic networks. Epilepsia 20080101
[Acute asthma and coma in Emergency Department: a case report]. Recenti progressi in medicina 20080101
Pharmacological Properties of DOV 315,090, an ocinaplon metabolite. BMC pharmacology 20080101
Delirium and its treatment. CNS drugs 20080101
The auditory cortex of the bat Phyllostomus discolor: Localization and organization of basic response properties. BMC neuroscience 20080101
Effect of flumazenil on disturbance of equilibrium function induced by midazolam. Anesthesia progress 20080101
Benzodiazepine/GABA(A) receptors are involved in magnesium-induced anxiolytic-like behavior in mice. Pharmacological reports : PR 20080101
Pre-hospital treatment of acute poisonings in Oslo. BMC emergency medicine 20080101
Pediatric procedural sedation and analgesia. Journal of emergencies, trauma, and shock 20080101
Carisoprodol-induced amnestic state. Indian journal of psychiatry 20080101
Effect of Withania somnifera on Sleep-Wake Cycle in Sleep-Disturbed Rats: Possible GABAergic Mechanism. Indian journal of pharmaceutical sciences 20080101
The effect of sympathetic antagonists on the antidepressant action of alprazolam. The Libyan journal of medicine 20080101
Tryptophan research in panic disorder. International journal of tryptophan research : IJTR 20080101
Effect of the diazepam-binding inhibitor-derived peptide, octadecaneuropeptide, on food intake in goldfish. Neuroscience 20071205
Insomnia: a ticking clock for depression? Journal of psychiatric research 20071201
Emerging synergisms between drugs and physiologically-patterned weak magnetic fields: implications for neuropharmacology and the human population in the twenty-first century. Current neuropharmacology 20071201
Anticonvulsant effect of wogonin isolated from Scutellaria baicalensis. European journal of pharmacology 20071128
Chlorogenic acid, a polyphenol from Prunus domestica (Mirabelle), with coupled anxiolytic and antioxidant effects. Journal of the neurological sciences 20071115
Effect of flumazenil-augmentation on microsleep and mood in depressed patients during partial sleep deprivation. Journal of psychiatric research 20071101
The amygdala regulates the antianxiety sensitization effect of flumazenil during repeated chronic ethanol or repeated stress. Alcoholism, clinical and experimental research 20071101
Partial antagonization of midazolam-medetomidine-ketamine in cats--atipamezole versus combined atipamezole and flumazenil. Journal of veterinary medicine. A, Physiology, pathology, clinical medicine 20071101
[Drug dependence syndrome as a side effect of medical drug use]. Nihon rinsho. Japanese journal of clinical medicine 20071028
The effect of ivermectin on convulsions in rats produced by lidocaine and strychnine. Veterinary research communications 20071001
Anxiolytic-like activity of the non-selective galanin receptor agonist, galnon. Neuropeptides 20071001
Anxiolytic-like effects of obovatol isolated from Magnolia obovata: involvement of GABA/benzodiazepine receptors complex. Progress in neuro-psychopharmacology & biological psychiatry 20071001
Delayed postoperative agitation in a child after preoperative midazolam. Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses 20071001
Open-label study of a proprietary treatment program targeting type A gamma-aminobutyric acid receptor dysregulation in methamphetamine dependence. Mayo Clinic proceedings 20071001
Evaluation of the anxiolytic effects of chrysin, a Passiflora incarnata extract, in the laboratory rat. AANA journal 20071001
Zolpidem modified-release in insomnia. Neuropsychiatric disease and treatment 20071001
Carisoprodol withdrawal induced delirium: A case study. Neuropsychiatric disease and treatment 20071001
Proximity-accelerated chemical coupling reaction in the benzodiazepine-binding site of gamma-aminobutyric acid type A receptors: superposition of different allosteric modulators. The Journal of biological chemistry 20070907
Piplartine, an amide alkaloid from Piper tuberculatum, presents anxiolytic and antidepressant effects in mice. Phytomedicine : international journal of phytotherapy and phytopharmacology 20070901
Contribution of specific binding to the central benzodiazepine site to the brain concentrations of two novel benzodiazepine site ligands. Biopharmaceutics & drug disposition 20070901
Drug challenges reveal differences in mediation of stress facilitation of voluntary alcohol drinking and withdrawal-induced anxiety in alcohol-preferring P rats. Alcoholism, clinical and experimental research 20070901
6,2'-Dihydroxyflavone, a subtype-selective partial inverse agonist of GABAA receptor benzodiazepine site. Neuropharmacology 20070901
Biological clocks and the practice of psychiatry. Dialogues in clinical neuroscience 20070901
Gefitinib and high-dose fractionated radiotherapy for carcinomatous encephalitis from non-small cell lung carcinoma. Biologics : targets & therapy 20070901
Flumazenil selectively prevents the increase in alpha(4)-subunit gene expression and an associated change in GABA(A) receptor function induced by ethanol withdrawal. Journal of neurochemistry 20070801
Systemic administration of the benzodiazepine receptor partial inverse agonist FG-7142 disrupts corticolimbic network interactions. Synapse (New York, N.Y.) 20070801
Usefulness of 123I-iomazenil single-photon emission computed tomography in discriminating between mesial and lateral temporal lobe epilepsy in patients in whom magnetic resonance imaging demonstrates normal findings. Journal of neurosurgery 20070801
Pharmacological characterization of the receptor mediating the anorexigenic action of the octadecaneuropeptide: evidence for an endozepinergic tone regulating food intake. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20070701
Should a benzodiazepine antagonist be used in unconscious patients presenting to the emergency department? Resuscitation 20070701
Lack of generalisation between the GABAA receptor agonist, gaboxadol, and allosteric modulators of the benzodiazepine binding site in the rat drug discrimination procedure. Psychopharmacology 20070701
Decreased Efficacy of GABAA-receptor modulation by midazolam in the kainate model of temporal lobe epilepsy. Epilepsia 20070701
Propofol for procedural sedation in the emergency department. Emergency medicine journal : EMJ 20070701
CNS 7056: a novel ultra-short-acting Benzodiazepine. Anesthesiology 20070701
Valerenic acid potentiates and inhibits GABA(A) receptors: molecular mechanism and subunit specificity. Neuropharmacology 20070701
Radiosynthesis and biological evaluation of an 18F-labeled derivative of the novel pyrazolopyrimidine sedative-hypnotic agent indiplon. Nuclear medicine and biology 20070701
Reduced gamma-aminobutyric acid(A)-benzodiazepine binding sites in insular cortex of individuals with panic disorder. Archives of general psychiatry 20070701
Effect of withdrawal of diazepam or morphine treatment on gastric motility (charcoal meal test) in mice: possible role of different central and peripheral receptors. Indian journal of experimental biology 20070701
Anxiolytic-like effects of sinapic acid in mice. Life sciences 20070627
Flumazenil-sensitive dose-related physical dependence in planarians produced by two benzodiazepine and one non-benzodiazepine benzodiazepine-receptor agonists. European journal of pharmacology 20070614
The CRF1 receptor antagonist R121919 attenuates the neuroendocrine and behavioral effects of precipitated lorazepam withdrawal. Psychopharmacology 20070601
Elevated zero maze: a paradigm to evaluate antianxiety effects of drugs. Methods and findings in experimental and clinical pharmacology 20070601
[A study of 355 consecutive acute poisoning cases admitted to an emergency ward at Copenhagen University Hospital, Bispebjerg in 2001]. Ugeskrift for laeger 20070507
Possible involvement of GABA A-benzodiazepine receptor in the anxiolytic-like effect induced by Passiflora actinia extracts in mice. Journal of ethnopharmacology 20070504
FG 7142 specifically reduces meal size and the rate and regularity of sustained feeding in female rats: evidence that benzodiazepine inverse agonists reduce food palatability. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20070501
Changes in relative potency among positive GABA(A) receptor modulators upon discontinuation of chronic benzodiazepine treatment in rhesus monkeys. Psychopharmacology 20070501
Zolpidem modulates GABA(A) receptor function in subthalamic nucleus. Neuroscience research 20070501
Allosteric uncoupling and up-regulation of benzodiazepine and GABA recognition sites following chronic diazepam treatment of HEK 293 cells stably transfected with alpha1beta2gamma2S subunits of GABA (A) receptors. Naunyn-Schmiedeberg's archives of pharmacology 20070501
Brain activity affects dynamic but not static autoregulation. Experimental neurology 20070501
Involvement of 5-HT1A and GABAA receptors in the anxiolytic-like effects of Cinnamomum cassia in mice. Pharmacology, biochemistry, and behavior 20070501
Efficient elimination of inhaled nanoparticles from the alveolar region: evidence for interstitial uptake and subsequent reentrainment onto airways epithelium. Environmental health perspectives 20070501
[Anxiety, panic and the hypothalamic-pituitary-adrenal axis]. Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) 20070501
Neuroprotection afforded by diazepam against oxygen/glucose deprivation-induced injury in rat cortical brain slices. European journal of pharmacology 20070430
Novel N-substituted indol-3-ylglyoxylamides probing the LDi and L1/L2 lipophilic regions of the benzodiazepine receptor site in search for subtype-selective ligands. Journal of medicinal chemistry 20070405
Anti-anxiety effects of Apocynum venetum L. in the elevated plus maze test. Journal of ethnopharmacology 20070404
Protective effect of safranal on pentylenetetrazol-induced seizures in the rat: involvement of GABAergic and opioids systems. Phytomedicine : international journal of phytotherapy and phytopharmacology 20070401
Unplanned 'unconsciousness' at Caesarean section: hysteria or drug reaction? International journal of obstetric anesthesia 20070401
Baclofen blocks expression and sensitization of anxiety-like behavior in an animal model of repeated stress and ethanol withdrawal. Alcoholism, clinical and experimental research 20070401
Extract of Ganoderma lucidum potentiates pentobarbital-induced sleep via a GABAergic mechanism. Pharmacology, biochemistry, and behavior 20070401
UK drug analysis prints and anaesthetic adverse drug reactions. Pharmacoepidemiology and drug safety 20070301
The novel anxiolytic ELB139 displays selectivity to recombinant GABA(A) receptors different from diazepam. Neuropharmacology 20070301
Comparison of lorazepam [7-chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one] occupancy of rat brain gamma-aminobutyric acid(A) receptors measured using in vivo [3H]flumazenil (8-fluoro 5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid ethyl ester) binding and [11C]flumazenil micro-positron emission tomography. The Journal of pharmacology and experimental therapeutics 20070301
Fast cardiologist-administered midazolam for electrical cardioversion of atrial fibrillation. Journal of cardiovascular medicine (Hagerstown, Md.) 20070301
Anxiolytic-like effect of group III mGlu receptor antagonist is serotonin-dependent. Neuropharmacology 20070201
Benzodiazepine inhibits hypothalamic presympathetic neurons by potentiation of GABAergic synaptic input. Neuropharmacology 20070201
Pharmacological analysis of the effects of benzodiazepines on punished schedule-induced polydipsia in rats. Behavioural pharmacology 20070201
The effects of benzodiazepines on orexinergic systems in rat cerebrocortical slices. Anesthesia and analgesia 20070201
Effects of gamma-aminobutyric acid-modulating drugs on working memory and brain function in patients with schizophrenia. Archives of general psychiatry 20070201
Coma cocktail: a role for flumazenil? British journal of hospital medicine (London, England : 2005) 20070201
Diazepam-induced disruption of classically-conditioned fear-potentiation of late-latency auditory evoked potentials is prevented by flumazenil given before, but not after, CS/US pairing. Journal of psychopharmacology (Oxford, England) 20070101
Dopamine and benzodiazepine-dependent mechanisms regulate the EtOH-enhanced locomotor stimulation in the GABAA alpha1 subunit null mutant mice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20070101
Assessment of regional GABA(A) receptor binding using 18F-fluoroflumazenil positron emission tomography in spastic type cerebral palsy. NeuroImage 20070101
Effect of GABAergic ligands on the anxiolytic-like activity of DOI (a 5-HT(2A/2C) agonist) in the four-plate test in mice. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20070101
In vivo evaluation of P-glycoprotein modulation of 8 PET radioligands used clinically. Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20070101
Association of vascular parkinsonism with impaired neuronal integrity in the striatum. Journal of neural transmission (Vienna, Austria : 1996) 20070101
Use of a novel mouse genotype to model acute benzodiazepine withdrawal. Behavior genetics 20070101
ELB139 an agonist at the benzodiazepine binding site increases 5-HT in the striatum and prefrontal cortex of rats: a microdialysis study. Pharmacology, biochemistry, and behavior 20070101
Tricyclic antidepressant poisoning: an evidence-based consensus guideline for out-of-hospital management. Clinical toxicology (Philadelphia, Pa.) 20070101
Neurobiology of memory and anxiety: from genes to behavior. Neural plasticity 20070101
Characterization of the interaction between fenamates and hippocampal neuron GABA(A) receptors. Neurochemistry international 20070101
Anticonvulsant effects of aerial parts of Passiflora incarnata extract in mice: involvement of benzodiazepine and opioid receptors. BMC complementary and alternative medicine 20070101
Multimodality data integration in epilepsy. International journal of biomedical imaging 20070101
Pharmacokinetic considerations in clinical toxicology: clinical applications. Clinical pharmacokinetics 20070101
Layer- and column-specific knockout of NMDA receptors in pyramidal neurons of the mouse barrel cortex. Frontiers in integrative neuroscience 20070101
Effects of calcium channel blockers on antidepressant action of Alprazolam and Imipramine. The Libyan journal of medicine 20070101
Effect of cyclooxygenase inhibitors on pentylenetetrazol (PTZ)-induced convulsions: Possible mechanism of action. Progress in neuro-psychopharmacology & biological psychiatry 20061230
Anxiolytic-like effect of cannabidiol in the rat Vogel conflict test. Progress in neuro-psychopharmacology & biological psychiatry 20061230
Felbamate is a subunit selective modulator of recombinant gamma-aminobutyric acid type A receptors expressed in Xenopus oocytes. European journal of pharmacology 20061215
The anxioselective agent 7-(2-chloropyridin-4-yl)pyrazolo-[1,5-a]-pyrimidin-3-yl](pyridin-2-yl)methanone (DOV 51892) is more efficacious than diazepam at enhancing GABA-gated currents at alpha1 subunit-containing GABAA receptors. The Journal of pharmacology and experimental therapeutics 20061201
Prolonged unconsciousness in a patient on automated peritoneal dialysis. European journal of emergency medicine : official journal of the European Society for Emergency Medicine 20061201
Changes in pulse oximetry levels and factors affecting oxygen saturation during routine upper gastrointestinal endoscopy with or without sedation. The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology 20061201
A possible mechanism for anxiolytic and antidepressant effects of alpha- and beta-amyrin from Protium heptaphyllum (Aubl.) March. Pharmacology, biochemistry, and behavior 20061201
Psychopharmacology of topiramate: from epilepsy to bipolar disorder. Neuropsychiatric disease and treatment 20061201
Anxiolytic effects of the aqueous extract of Uncaria rhynchophylla. Journal of ethnopharmacology 20061124
Effects of genetic background and null mutation of 5-HT1A receptors on basal and stress-induced body temperature: modulation by serotonergic and GABAA-ergic drugs. European journal of pharmacology 20061121
An inverse agonist selective for alpha5 subunit-containing GABAA receptors improves encoding and recall but not consolidation in the Morris water maze. Psychopharmacology 20061101
GABAA receptor regulation of voluntary ethanol drinking requires PKCepsilon. Synapse (New York, N.Y.) 20061101
Pre-surgical identification of epileptogenic areas in temporal lobe epilepsy by 123I-iomazenil SPECT: a comparison with IMP SPECT and FDG PET. Nuclear medicine communications 20061101
Iomazenil-single-photon emission computed tomography reveals selective neuronal loss in magnetic resonance-defined mismatch areas. Stroke 20061101
Chronic intragastric administration of gamma-butyrolactone produces physical dependence in baboons. Psychopharmacology 20061101
Adequacy of antidote stocking in British Columbia hospitals: the 2005 Antidote Stocking Study. CJEM 20061101
The proconvulsant effects of the GABAA alpha5 subtype-selective compound RY-080 may not be alpha5-mediated. European journal of pharmacology 20061024
Intravenous flumazenil for Parkinson's disease: a single dose, double blind, placebo controlled, cross-over trial. Movement disorders : official journal of the Movement Disorder Society 20061001
Effects of diazepam on 125I-iomazenil-benzodiazepine receptor binding and epileptic seizures in the El mouse. Annals of nuclear medicine 20061001
Optimization algorithms and weighting factors for analysis of dynamic PET studies. Physics in medicine and biology 20060907
Lorazepam-induced effects on silent period and corticomotor excitability. Experimental brain research 20060901
A GABAA receptor mutation causing generalized epilepsy reduces benzodiazepine receptor binding. NeuroImage 20060901
Efficacy and the discriminative stimulus effects of negative GABAA modulators, or inverse agonists, in diazepam-treated rhesus monkeys. The Journal of pharmacology and experimental therapeutics 20060801
Focal cortical dysplasia: pathophysiological approach. Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 20060801
Enhanced sucrose pellet consumption induced by benzodiazepine-type drugs in squirrel monkeys: role of GABAA receptor subtypes. Psychopharmacology 20060801
Anticonvulsant effect of the selective 5-HT1B receptor agonist CP 94253 in mice. European journal of pharmacology 20060710
Antidepressant-like effect of harmane and other beta-carbolines in the mouse forced swim test. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20060701
Tolerance to the antinociceptive effects of ethanol during ethanol withdrawal. Progress in neuro-psychopharmacology & biological psychiatry 20060701
Protective effect of BR-16A, a polyherbal preparation against social isolation stress: possible GABAergic mechanism. Phytotherapy research : PTR 20060701
Comparison of in vivo and ex vivo [3H]flumazenil binding assays to determine occupancy at the benzodiazepine binding site of rat brain GABAA receptors. Neuropharmacology 20060701
Flumazenil mimics whereas midazolam abolishes ischemic preconditioning in a rabbit heart model of ischemia-reperfusion. Anesthesiology 20060701
[Influence of benzodiazepines on 123I iomazenil SPECT]. No to hattatsu = Brain and development 20060701
Sexual assault and posttraumatic stress disorder: a review of the biological, psychological and sociological factors and treatments. McGill journal of medicine : MJM : an international forum for the advancement of medical sciences by students 20060701
Cardiotonic and sedative effects of Cecropia pachystachya Mart. (ambay) on isolated rat hearts and conscious mice. Journal of ethnopharmacology 20060615
Pharmacological evaluation of an [(123)I] labelled imidazopyridine-3-acetamide for the study of benzodiazepine receptors. Life sciences 20060613
Behavioral effects of opioid subtypes compared with benzodiazepines in the staircase paradigm. Behavioural brain research 20060603
Neurosteroids, GABAA receptors, and ethanol dependence. Psychopharmacology 20060601
Steroid withdrawal in the mouse results in anxiogenic effects of 3alpha,5beta-THP: a possible model of premenstrual dysphoric disorder. Psychopharmacology 20060601
Synthesis and in vitro binding of N,N-dialkyl-2-phenylindol-3-yl-glyoxylamides for the peripheral benzodiazepine binding sites. Bioorganic & medicinal chemistry 20060601
An interaction between benzodiazepines and neuroactive steroids at GABA A receptors in cultured hippocampal neurons. Neurochemistry international 20060601
Acute and chronic effects of ramelteon in rhesus monkeys (Macaca mulatta): dependence liability studies. Behavioral neuroscience 20060601
An investigation of flumazenil to antagonize gamma-hydroxybutyrate intoxication in a murine model. Journal of medical toxicology : official journal of the American College of Medical Toxicology 20060601
The in vivo properties of pagoclone in rat are most likely mediated by 5'-hydroxy pagoclone. Neuropharmacology 20060501
Involvement of diazepam-insensitive benzodiazepine receptors in the suppression of DOI-induced head-twitch responses in diabetic mice. Psychopharmacology 20060501
Discriminative stimulus effects of flumazenil: perceptual masking by baclofen, and lack of substitution with gamma-hydroxybutyrate and its precursors 1,4-butanediol and gamma-butyrolactone. Behavioural pharmacology 20060501
Effects of drugs acting on the GABA-benzodiazepine receptor complex on flurothyl-induced seizures in Mongolian gerbils. European journal of pharmacology 20060501
Microsphere-based protease assays and screening application for lethal factor and factor Xa. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Clinical evaluation of intranasal benzodiazepines, alpha-agonists and their antagonists in canaries. Veterinary anaesthesia and analgesia 20060501
SPECT quantification of benzodiazepine receptor concentration using a dual-ligand approach. Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20060501
Acute treatment with pentobarbital alters the kinetics of in vivo receptor binding in the mouse brain. Nuclear medicine and biology 20060501
The lack of bicuculline and picrotoxin influence on midazolam depressant action on brain oxygen consumption. Neuroscience letters 20060424
Refinement of the benzodiazepine receptor site topology by structure-activity relationships of new N-(heteroarylmethyl)indol-3-ylglyoxylamides. Journal of medicinal chemistry 20060420
Discriminative stimulus effects of gamma-hydroxybutyrate: role of training dose. The Journal of pharmacology and experimental therapeutics 20060401
Stiripentol, a putative antiepileptic drug, enhances the duration of opening of GABA-A receptor channels. Epilepsia 20060401
Diazepam enhances inotropic responses to dopamine in rat ventricular myocardium. Anesthesia and analgesia 20060301
Evidence-based emergency medicine/systematic review abstract. Is flumazenil an effective treatment for hepatic encephalopathy? Annals of emergency medicine 20060301
The alkaloid alstonine: a review of its pharmacological properties. Evidence-based complementary and alternative medicine : eCAM 20060301
Danger of flumazenil use in pediatric status epilepticus. Pediatric emergency care 20060301
Benzodiazepine receptor ligands. 8: synthesis and pharmacological evaluation of new pyrazolo[5,1-c] [1,2,4]benzotriazine 5-oxide 3- and 8-disubstituted: high affinity ligands endowed with inverse-agonist pharmacological efficacy. Bioorganic & medicinal chemistry 20060201
Pharmacological properties of GABAA receptors containing gamma1 subunits. Molecular pharmacology 20060201
Autoradiographic localization and binding study of benzodiazepines receptor sites in carp brain (Cyprinus carpio L.). Journal of chemical neuroanatomy 20060201
Diazepam inhibits the induction and maintenance of LTP of C-fiber evoked field potentials in spinal dorsal horn of rats. Neuropharmacology 20060201
Differential behavioral effects of low efficacy positive GABAA modulators in combination with benzodiazepines and a neuroactive steroid in rhesus monkeys. British journal of pharmacology 20060201
Cerebral oxygen metabolism and neuronal integrity in patients with impaired vasoreactivity attributable to occlusive carotid artery disease. Stroke 20060201
Actions of midazolam on excitatory transmission in dorsal horn neurons of adult rat spinal cord. Anesthesiology 20060201
Use of Flumazenil in benzodiazepine overdose. Emergency medicine journal : EMJ 20060201
Sedative effects of midazolam and xylazine with or without ketamine and detomidine alone following intranasal administration in Ring-necked Parakeets. Journal of the American Veterinary Medical Association 20060201
Anxiolytic-like effects of Gastrodia elata and its phenolic constituents in mice. Biological & pharmaceutical bulletin 20060201
Biflavones from Rhus species with affinity for the GABA(A)/benzodiazepine receptor. Journal of ethnopharmacology 20060116
Sedative, antiepileptic and antipsychotic effects of Spondias mombin L. (Anacardiaceae) in mice and rats. Journal of ethnopharmacology 20060116
gamma-Aminobutyric acid-serotonin interactions in healthy men: implications for network models of psychosis and dissociation. Biological psychiatry 20060115
GABA(A) receptors mediate orexin-A induced stimulation of food intake. Neuropharmacology 20060101
TPA023 [7-(1,1-dimethylethyl)-6-(2-ethyl-2H-1,2,4-triazol-3-ylmethoxy)-3-(2-fluorophenyl)-1,2,4-triazolo[4,3-b]pyridazine], an agonist selective for alpha2- and alpha3-containing GABAA receptors, is a nonsedating anxiolytic in rodents and primates. The Journal of pharmacology and experimental therapeutics 20060101
Focal glucose hypermetabolism in interictal state of West syndrome. Pediatric neurology 20060101
Anti-conflict effects of benzodiazepines in rhesus monkeys: relationship with therapeutic doses in humans and role of GABAA receptors. Psychopharmacology 20060101
Chemical immobilization of adult female Weddell seals with tiletamine and zolazepam: effects of age, condition and stage of lactation. BMC veterinary research 20060101
What does flumazenil PET add to an evaluation for temporal lobectomy? Epilepsy currents 20060101
Sedation and analgesia for gastrointestinal endoscopy during pregnancy. Gastrointestinal endoscopy clinics of North America 20060101
[Participation of GABA--benzodiazepine receptor complex in the anxiolytic effect of piracetam]. Eksperimental'naia i klinicheskaia farmakologiia 20060101
A comparison of 3 routes of flumazenil administration to reverse benzodiazepine-induced desaturation in an animal model. Pediatric dentistry 20060101
Antidote use in the critically ill poisoned patient. Journal of intensive care medicine 20060101
[Midazolam (dormicump)--clinical practice guidelines]. Medicinski pregled 20060101
Adenosine receptor antagonists intensify the benzodiazepine withdrawal signs in mice. Pharmacological reports : PR 20060101
Combination phenylbutyrate/gemcitabine therapy effectively inhibits in vitro and in vivo growth of NSCLC by intrinsic apoptotic pathways. Journal of carcinogenesis 20060101
Ligand-based approach to in silico pharmacology: nuclear receptor profiling. Journal of chemical information and modeling 20060101
Anxiolytic-like effects of group III mGlu receptor ligands in the hippocampus involve GABAA signaling. Pharmacological reports : PR 20060101
The astrocytic GABA(A)/benzodiazepine-like receptor: the Joker receptor for benzodiazepine-mimetic drugs? Recent patents on CNS drug discovery 20060101
Post-operative delirium after hip fracture treatment - a review of the current literature. Psycho-social medicine 20060101
Effects of GABAergic modulators on food and cocaine self-administration in baboons. Drug and alcohol dependence 20051212
Endozepines in recurrent stupor. Sleep medicine reviews 20051201
Abnormal benzodiazepine receptor function in the depressive-like behavior of diabetic mice. Pharmacology, biochemistry, and behavior 20051201
Selective neuronal damage and borderzone infarction in carotid artery occlusive disease: a 11C-flumazenil PET study. Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20051201
Midazolam for patients undergoing upper gastrointestinal endoscopy: a prospective, single-blind and randomized study to determine the appropriate amount and time of initiation of endoscopy. Journal of gastroenterology and hepatology 20051201
Role of endogenous benzodiazepine ligands and their GABA-A--associated receptors in hepatic encephalopathy. Metabolic brain disease 20051201
Benzodiazepine involvement in LTP of the GABA-ergic IPSC in rat hippocampal CA1 neurons. Brain research 20051116
Synthesis and in vivo evaluation of a novel peripheral benzodiazepine receptor PET radioligand. Bioorganic & medicinal chemistry 20051115
A comparison of chlordiazepoxide, bretazenil, L838,417 and zolpidem in a validated mouse Vogel conflict test. Psychopharmacology 20051101
Selective labelling of diazepam-insensitive GABAA receptors in vivo using [3H]Ro 15-4513. British journal of pharmacology 20051101
Population plasma pharmacokinetics of 11C-flumazenil at tracer concentrations. British journal of clinical pharmacology 20051101
Ultrafine particles cross cellular membranes by nonphagocytic mechanisms in lungs and in cultured cells. Environmental health perspectives 20051101
Individual differences in aggressive responding to intravenous flumazenil administration in adult male parolees. Journal of psychopharmacology (Oxford, England) 20051101
Influence of adenosine receptor agonists on benzodiazepine withdrawal signs in mice. European journal of pharmacology 20051031
Negative GABA(A) modulators attenuate the discriminative stimulus effects of benzodiazepines and the neuroactive steroid pregnanolone in rhesus monkeys. Psychopharmacology 20051001
Low tolerance and dependence liabilities of etizolam: molecular, functional, and pharmacological correlates. European journal of pharmacology 20050905
Comparison of the behavioral effects of bretazenil and flumazenil in triazolam-dependent and non-dependent baboons. European journal of pharmacology 20050905
Prior multiple ethanol withdrawals enhance stress-induced anxiety-like behavior: inhibition by CRF1- and benzodiazepine-receptor antagonists and a 5-HT1a-receptor agonist. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20050901
Anxiolytic-like actions of testosterone in the burying behavior test: role of androgen and GABA-benzodiazepine receptors. Psychoneuroendocrinology 20050901
Novel plant substances acting as beta subunit isoform-selective positive allosteric modulators of GABAA receptors. Molecular pharmacology 20050901
Dependence on zolpidem: two case reports of detoxification with flumazenil infusion. International clinical psychopharmacology 20050901
Abnormal cortical excitability in sporadic but not homozygous D90A SOD1 ALS. Journal of neurology, neurosurgery, and psychiatry 20050901
Subanesthetic ketamine does not affect 11C-flumazenil binding in humans. Anesthesia and analgesia 20050901
Does the panic attack activate the hypothalamic-pituitary-adrenal axis? Anais da Academia Brasileira de Ciencias 20050901
On the mechanism of anticonvulsant effect of tramadol in mice. Pharmacology, biochemistry, and behavior 20050901
Genetic influences in emotional dysfunction and alcoholism-related brain damage. Neuropsychiatric disease and treatment 20050901
Differential effects of acute diazepam on emotional and neutral memory tasks in acutely hospitalized depressed patients. Neuropsychiatric disease and treatment 20050901
Changes in hippocampal GABAA receptor subunit composition in bipolar 1 disorder. Brain research. Molecular brain research 20050818
Characterization in rats of the anxiolytic potential of ELB139 [1-(4-chlorophenyl)-4-piperidin-1-yl-1,5-dihydro-imidazol-2-on], a new agonist at the benzodiazepine binding site of the GABAA receptor. The Journal of pharmacology and experimental therapeutics 20050801
GABA-benzodiazepine receptor function in alcohol dependence: a combined 11C-flumazenil PET and pharmacodynamic study. Psychopharmacology 20050801
A proof-of-concept study using [11C]flumazenil PET to demonstrate that pagoclone is a partial agonist. Psychopharmacology 20050801
In vivo labelling of alpha5 subunit-containing GABA(A) receptors using the selective radioligand [(3)H]L-655,708. Neuropharmacology 20050801
Cortical gamma-aminobutyric acid type A-benzodiazepine receptors in recovery from alcohol dependence: relationship to features of alcohol dependence and cigarette smoking. Archives of general psychiatry 20050801
Chronic treatment with flumazenil enhances binding sites for convulsants at recombinant alpha(1)beta(2)gamma(2S) GABA(A) receptors. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20050801
Selective GABAA alpha5 benzodiazepine inverse agonist antagonizes the neurobehavioral actions of alcohol. Alcoholism, clinical and experimental research 20050801
Effects of kava-kava extract on the sleep-wake cycle in sleep-disturbed rats. Psychopharmacology 20050701
Bidirectional effects of benzodiazepine binding site ligands on active avoidance acquisition and retention: differential antagonism by flumazenil and beta-CCt. Psychopharmacology 20050701
Differential effects of ammonia on the benzodiazepine modulatory site on the GABA-A receptor complex of human brain. Neurochemistry international 20050701
Anxiolytic-like effect of milnacipran in the four-plate test in mice: mechanism of action. Pharmacology, biochemistry, and behavior 20050701
Placebo in emotional processing--induced expectations of anxiety relief activate a generalized modulatory network. Neuron 20050616
Design and synthesis of new 2-substituted-5-(2-benzylthiophenyl)-1,3,4-oxadiazoles as benzodiazepine receptor agonists. Bioorganic & medicinal chemistry letters 20050615
Seizure-related short-term plasticity of benzodiazepine receptors in partial epilepsy: a [11C]flumazenil-PET study. Brain : a journal of neurology 20050601
Distinct cerebral lesions in sporadic and 'D90A' SOD1 ALS: studies with [11C]flumazenil PET. Brain : a journal of neurology 20050601
The four-plates test-retest paradigm to discriminate anxiolytic effects. Psychopharmacology 20050601
Resuscitative effect of a gamma-aminobutyric acid B receptor antagonist on gamma-hydroxybutyric acid mortality in mice. Annals of emergency medicine 20050601
Periventricular white matter flumazenil binding and postoperative outcome in hippocampal sclerosis. Epilepsia 20050601
Prediction of genotoxicity of chemical compounds by statistical learning methods. Chemical research in toxicology 20050601
Changes in peripheral benzodiazepine receptors in patients with bipolar disorder. Neuropsychiatric disease and treatment 20050601
Two flavonoids from Artemisia herba-alba Asso with in vitro GABAA-benzodiazepine receptor activity. Journal of ethnopharmacology 20050513
Hypnotic activities of chamomile and passiflora extracts in sleep-disturbed rats. Biological & pharmaceutical bulletin 20050501
Pharmacological modulation of repeated ethanol withdrawal-induced anxiety-like behavior differs in alcohol-preferring P and Sprague-Dawley rats. Pharmacology, biochemistry, and behavior 20050501
The role of flumazenil in self harm with benzodiazepines: to give or not to give? Hospital medicine (London, England : 1998) 20050501
High affinity central benzodiazepine receptor ligands: synthesis and biological evaluation of a series of phenyltriazolobenzotriazindione derivatives. Journal of medicinal chemistry 20050421
6-Methylflavanone, a more efficacious positive allosteric modulator of gamma-aminobutyric acid (GABA) action at human recombinant alpha2beta2gamma2L than at alpha1beta2gamma2L and alpha1beta2 GABA(A) receptors expressed in Xenopus oocytes. European journal of pharmacology 20050411
(+)- And (-)-borneol: efficacious positive modulators of GABA action at human recombinant alpha1beta2gamma2L GABA(A) receptors. Biochemical pharmacology 20050401
Classic benzodiazepines modulate the open-close equilibrium in alpha1beta2gamma2L gamma-aminobutyric acid type A receptors. Anesthesiology 20050401
Intracerebroventricular administration of thymoquinone, the major constituent of Nigella sativa seeds, suppresses epileptic seizures in rats. Medical science monitor : international medical journal of experimental and clinical research 20050401
Ethyl 5-isopropoxy-4-methyl-beta-carboline-3-carboxylate: structural determinants of benzodiazepine-receptor antagonism. Acta crystallographica. Section C, Crystal structure communications 20050401
Biological properties of 2'-[18F]fluoroflumazenil for central benzodiazepine receptor imaging. Nuclear medicine and biology 20050401
Modulation of ethanol withdrawal-induced anxiety-like behavior during later withdrawals by treatment of early withdrawals with benzodiazepine/gamma-aminobutyric acid ligands. Alcoholism, clinical and experimental research 20050401
Flumazenil-induced improvement of the central dopaminergic system in rats with acute hepatic failure. Journal of neurosurgical anesthesiology 20050401
Liquid chromatographic-mass spectrometric method for the determination of fluoxetine and norfluoxetine in human plasma: application to clinical study. Farmaco (Societa chimica italiana : 1989) 20050401
[Ischemic brain infarction after an air embolism. Case report]. Revista medica de Chile 20050401
Bidirectional effects of benzodiazepine binding site ligands in the passive avoidance task: differential antagonism by flumazenil and beta-CCt. Behavioural brain research 20050330
Role of GABA-ergic and serotonergic systems in the anxiolytic-like mechanism of action of a 5-HT-moduline antagonist in the mouse elevated plus maze. Behavioural brain research 20050330
Benzodiazepines and heightened aggressive behavior in rats: reduction by GABA(A)/alpha(1) receptor antagonists. Psychopharmacology 20050301
Flumazenil-precipitated withdrawal in healthy volunteers following repeated diazepam exposure. Psychopharmacology 20050301
Benzodiazepine receptor-dependent modulation of neutrophil (PMN) free amino- and alpha-keto acid profiles or immune functions. Amino acids 20050201
The anxiolytic-like effect of 5-HT1B receptor ligands in rats: a possible mechanism of action. The Journal of pharmacy and pharmacology 20050201
Preparation of highly specific radioactivity [18F]flumazenil and its evaluation in cynomolgus monkey by positron emission tomography. Nuclear medicine and biology 20050201
Benzodiazepine system is involved in hyperalgesia in rats induced by the exposure to extremely low frequency magnetic fields. Archives of pharmacal research 20050201
Acetylcholine in the accumbens is decreased by diazepam and increased by benzodiazepine withdrawal: a possible mechanism for dependency. European journal of pharmacology 20050131
Haloperidol plus promethazine for psychosis induced aggression. The Cochrane database of systematic reviews 20050125
Activity of a traditional South African epilepsy remedy in the GABA-benzodiazepine receptor assay. Journal of ethnopharmacology 20050115
Enhancement of benzodiazepine binding sites following chronic treatment with flumazenil. European journal of pharmacology 20050110
Rodent pharmacokinetics and receptor occupancy of the GABAA receptor subtype selective benzodiazepine site ligand L-838417. Biopharmaceutics & drug disposition 20050101
[Utility of routine use of reversion after sedation in outpatient colonoscopy]. Gastroenterologia y hepatologia 20050101
Benzodiazepine effect of (125)I-iomazenil-benzodiazepine receptor binding and serum corticosterone level in a rat model. Nuclear medicine and biology 20050101
Differentiating midazolam over-sedation from neurological damage in the intensive care unit. Critical care (London, England) 20050101
[Central hemodynamic changes in children reoperated on for congenital spinal cord hernia using balanced anesthesia based on midasolam and propofol]. Anesteziologiia i reanimatologiia 20050101
Central-type benzodiazepine receptors and epileptogenesis: basic mechanisms and clinical validity. Epilepsia 20050101
Between benzodiazepine over-sedation and neurological damage. Critical care (London, England) 20050101
Effect of flumazenil on recovery from sevoflurane anesthesia in children premedicated with oral midazolam before undergoing herniorrhaphy with or without caudal analgesia. Journal of anesthesia 20050101
Zopiclone overdose responsive to flumazenil. Clinical toxicology (Philadelphia, Pa.) 20050101
Population pharmacokinetic analysis for simultaneous determination of B (max) and K (D) in vivo by positron emission tomography. Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 20050101
Chronic exposure of cells expressing recombinant GABAA receptors to benzodiazepine antagonist flumazenil enhances the maximum number of benzodiazepine binding sites. Life sciences 20041203
Discriminative stimulus effects in rats of SR-141716 (rimonabant), a cannabinoid CB1 receptor antagonist. Psychopharmacology 20041201
Increased brain concentrations of endogenous (non-benzodiazepine) GABA-A receptor ligands in human hepatic encephalopathy. Metabolic brain disease 20041201
Pathophysiology of hepatic encephalopathy: a new look at GABA from the molecular standpoint. Metabolic brain disease 20041201
The coma cocktail: indications, contraindications, adverse effects, proper dose, and proper route. Journal of emergency nursing: JEN : official publication of the Emergency Department Nurses Association 20041201
Melatonin inhibits the development of tolerance to U-50,488H analgesia via benzodiazepine-GABAAergic mechanisms. Pharmacology, biochemistry, and behavior 20041201
Clinical utility of 11C-flumazenil positron emission tomography in intractable temporal lobe epilepsy. Neurology India 20041201
In vivo pharmacological characterization of indiplon, a novel pyrazolopyrimidine sedative-hypnotic. The Journal of pharmacology and experimental therapeutics 20041101
Characterization of the interaction of indiplon, a novel pyrazolopyrimidine sedative-hypnotic, with the GABAA receptor. The Journal of pharmacology and experimental therapeutics 20041101
Sevoflurane and propofol increase 11C-flumazenil binding to gamma-aminobutyric acidA receptors in humans. Anesthesia and analgesia 20041101
Multiple GABAA receptor subtypes regulate hippocampal ripple oscillations. The European journal of neuroscience 20041001
Anticonvulsant efficacy of the low-affinity partial benzodiazepine receptor agonist ELB 138 in a dog seizure model and in epileptic dogs with spontaneously recurrent seizures. Epilepsia 20041001
Bidirectional effects of benzodiazepine binding site ligands in the elevated plus-maze: differential antagonism by flumazenil and beta-CCt. Pharmacology, biochemistry, and behavior 20041001
Difficulties in assessing brain death in a case of benzodiazepine poisoning with persistent cerebral blood flow. Human & experimental toxicology 20041001
Evaluation of the use of a standard input function for compartment analysis of [123I]iomazenil data: factors influencing the quantitative results. Annals of nuclear medicine 20041001
Discrepancy between cell injury and benzodiazepine receptor binding after transient middle cerebral artery occlusion in rats. Synapse (New York, N.Y.) 20040915
Determination of flumazenil in human plasma by liquid chromatography-electrospray ionisation tandem mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040905
Anxiolytic-like effects of MTEP, a potent and selective mGlu5 receptor agonist does not involve GABA(A) signaling. Neuropharmacology 20040901
Single-dose parenteral pharmacological interventions for the prevention of postoperative shivering: a quantitative systematic review of randomized controlled trials. Anesthesia and analgesia 20040901
Asystole and bradycardia related to anesthetic induction during ECT: a case report. The journal of ECT 20040901
Correct localization of epileptogenic focus with I-123 iomazenil cerebral benzodiazepine receptor imaging: a case report of temporal lobe epilepsy with discordant ictal cerebral blood flow SPECT. Annals of nuclear medicine 20040901
Probability of cortical infarction predicted by flumazenil binding and diffusion-weighted imaging signal intensity: a comparative positron emission tomography/magnetic resonance imaging study in early ischemic stroke. Stroke 20040801
Facilitation of cholinergic transmission by combined treatment of ondansetron with flumazenil after cortical cholinergic deafferentation. Neuropharmacology 20040801
Emergency drug availability on general paediatric units. Resuscitation 20040801
Flumazenil positron emission tomography and other ligands for functional imaging. Neuroimaging clinics of North America 20040801
Screening, library-assisted identification and validated quantification of 23 benzodiazepines, flumazenil, zaleplone, zolpidem and zopiclone in plasma by liquid chromatography/mass spectrometry with atmospheric pressure chemical ionization. Journal of mass spectrometry : JMS 20040801
Central type benzodiazepine receptors in Gulf War veterans with posttraumatic stress disorder. Biological psychiatry 20040715
GABAA receptor modulation of trigeminovascular nociceptive neurotransmission by midazolam is antagonized by flumazenil. Brain research 20040709
Analysis of microsomal metabolic stability using high-flow-rate extraction coupled to capillary liquid chromatography-mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040705
Alprazolam is relatively more toxic than other benzodiazepines in overdose. British journal of clinical pharmacology 20040701
[Effect of flumazenil on hypoglossal and phrenic nerves activities in rabbits]. Masui. The Japanese journal of anesthesiology 20040701
Effectiveness of antagonists for tiletamine-zolazepam/xylazine immobilization in female white-tailed deer. Journal of wildlife diseases 20040701
Effects of GABA modulators on the repeated acquisition of response sequences in squirrel monkeys. Journal of the experimental analysis of behavior 20040701
Use of a standardized uptake value for parametric in vivo imaging of benzodiazepine receptor distribution on [11C]flumazenil brain PET. European journal of nuclear medicine and molecular imaging 20040601
Pharmacological plasticity of GABA(A) receptors at dentate gyrus synapses in a rat model of temporal lobe epilepsy. The Journal of physiology 20040601
Club drugs: MDMA, gamma-hydroxybutyrate (GHB), Rohypnol, and ketamine. American family physician 20040601
Anaesthesia with midazolam/medetomidine/fentanyl in chinchillas (Chinchilla lanigera) compared to anaesthesia with xylazine/ketamine and medetomidine/ketamine. Journal of veterinary medicine. A, Physiology, pathology, clinical medicine 20040601
[Functional neuroimaging in adults]. Revue neurologique 20040601
The Discriminative stimulus effects of gamma-hydroxybutyrate and related compounds in rats discriminating baclofen or diazepam: The role of GABA(B) and GABA(A) receptors. The Journal of pharmacology and experimental therapeutics 20040501
Salicylidene salicylhydrazide, a selective inhibitor of beta 1-containing GABAA receptors. British journal of pharmacology 20040501
GABA A receptor abnormalities in Prader-Willi syndrome assessed with positron emission tomography and [11C]flumazenil. NeuroImage 20040501
Reversal of an antihistamine-induced coma with flumazenil. Pediatric emergency care 20040501
Flumazenil-independent positive modulation of gamma-aminobutyric acid action by 6-methylflavone at human recombinant alpha1beta2gamma2L and alpha1beta2 GABAA receptors. European journal of pharmacology 20040426
Decrease in cortical benzodiazepine receptors in symptomatic patients with leukoaraiosis: a positron emission tomography study. Stroke 20040401
Electrophysiological and behavioral effects of zolpidem in rat globus pallidus. Experimental neurology 20040401
GABAA/alpha1 receptor agonists and antagonists: effects on species-typical and heightened aggressive behavior after alcohol self-administration in mice. Psychopharmacology 20040301
In the amygdala anxiolytic action of mGlu5 receptors antagonist MPEP involves neuropeptide Y but not GABAA signaling. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20040301
Response to flumazenil in the late luteal phase and follicular phase of the menstrual cycle in healthy control females. Psychopharmacology 20040301
Discriminative stimulus effects of gamma-hydroxybutyrate in pigeons: role of diazepam-sensitive and -insensitive GABA(A) and GABA(B) receptors. The Journal of pharmacology and experimental therapeutics 20040301
Validation of a multiwell gamma-counter for measuring high-pressure liquid chromatography metabolite profiles. Journal of nuclear medicine technology 20040301
Reversible anesthesia of captive California sea lions (Zalophus californianus) with medetomidine, midazolam, butorphanol, and isoflurane. Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians 20040301
Benzodiazepine-sensitive GABA(A) receptors in the commissural subnucleus of the NTS are involved in the carotid chemoreceptor reflex in rats. Autonomic neuroscience : basic & clinical 20040227
Diminished GABA(A) receptor-binding capacity and a DNA base substitution in a patient with treatment-resistant depression and anxiety. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20040201
Flumazenil does not affect intracortical motor excitability in humans: a transcranial magnetic stimulation study. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 20040201
125I-iomazenil - benzodiazepine receptor binding and serum corticosterone level during psychological stress in a rat model. Nuclear medicine and biology 20040201
Biological evaluation of 2'-[18F]fluoroflumazenil ([18F]FFMZ), a potential GABA receptor ligand for PET. Nuclear medicine and biology 20040201
SB242084, flumazenil, and CRA1000 block ethanol withdrawal-induced anxiety in rats. Alcohol (Fayetteville, N.Y.) 20040201
[New concepts in the physiopathology of hepatic encephalopathy and therapeutic prospects]. Gastroenterologia y hepatologia 20040201
Production of 5alpha-reduced neurosteroids is developmentally regulated and shapes GABA(A) miniature IPSCs in lamina II of the spinal cord. The Journal of neuroscience : the official journal of the Society for Neuroscience 20040128
Stress-induced increase of cortical dopamine metabolism: attenuation by a tachykinin NK1 receptor antagonist. European journal of pharmacology 20040119
Use of the elevated T-maze to study anxiety in mice. Behavioural brain research 20040105
Behavioral effects of flumazenil in the social conflict test in mice. Psychopharmacology 20040101
Characterisation of [123I]iomazenil distribution in a rat model of focal cerebral ischaemia in relation to histopathological findings. European journal of nuclear medicine and molecular imaging 20040101
Anticonvulsant and antiepileptogenic effects of GABAA receptor ligands in pentylenetetrazole-kindled mice. Progress in neuro-psychopharmacology & biological psychiatry 20040101
The influence of midazolam on active avoidance retrieval and acquisition rate in rats. Pharmacology, biochemistry, and behavior 20040101
Inhibition of type A GABA receptors by L-type calcium channel blockers. Neuroscience 20040101
Anticonvulsant effects of thymoquinone, the major constituent of Nigella sativa seeds, in mice. Phytomedicine : international journal of phytotherapy and phytopharmacology 20040101
Effects of metabolite correction for arterial input function on quantitative receptor images with 11C-flumazenil in clinical positron emission tomography studies. Journal of computer assisted tomography 20040101
Benzodiazepine receptor antagonists for hepatic encephalopathy. The Cochrane database of systematic reviews 20040101
Oral triazolam sedation in implant dentistry. The Journal of oral implantology 20040101
Flumazenil--treatment or toxin. Journal of toxicology. Clinical toxicology 20040101
A near-fatal overdose of carisoprodol (SOMA): case report. Journal of toxicology. Clinical toxicology 20040101
Benzodiazepine receptor distribution in severe intractable tinnitus. The international tinnitus journal 20040101
Quantitative evaluation of central-type benzodiazepine receptors with [(125)I] Iomazenil in experimental epileptogenesis. I. The rat kainate model of temporal lobe epilepsy. Epilepsy research 20040101
Quantitative evaluation of central-type benzodiazepine receptors with [(125)I]Iomazenil in experimental epileptogenesis: II. The rat cortical dysplasia model. Epilepsy research 20040101
[Acute intoxication with baclofen]. Przeglad lekarski 20040101
[Neurobiology and pharmacotherapy of social phobia]. L'Encephale 20040101
Changes in GABA(A) receptor gene expression associated with selective alterations in receptor function and pharmacology after ethanol withdrawal. The Journal of neuroscience : the official journal of the Society for Neuroscience 20031217
[Hepatic encephalopathy--therapy]. Deutsche medizinische Wochenschrift (1946) 20031212
Quantification of human brain benzodiazepine receptors using [18F]fluoroethylflumazenil: a first report in volunteers and epileptic patients. European journal of nuclear medicine and molecular imaging 20031201
Sedation for cardioversion in the emergency department: analysis of effectiveness in four protocols. Annals of emergency medicine 20031201
Intravenous midazolam sedation in pediatric diagnostic upper digestive endoscopy. A prospective study in a general hospital. Romanian journal of gastroenterology 20031201
[How do diazepam and flumazenil influence respiratory control by the activities of both hypoglossal and phrenic nerves in rabbits?]. Masui. The Japanese journal of anesthesiology 20031201
Newer aspects of hepatic encephalopathy. Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology 20031201
Normal coupling of brain benzodiazepine and neurosteroid modulatory sites on the GABA-A receptor complex in human hepatic encephalopathy. Neurochemistry international 20031101
Characterization of endozepines in the human testicular tissue: effect of triakontatetraneuropeptide on testosterone secretion. The Journal of clinical endocrinology and metabolism 20031101
Safe and efficacious use of procedural sedation and analgesia by nonanesthesiologists in a pediatric emergency department. Archives of pediatrics & adolescent medicine 20031101
Continuous-infusion flumazenil in the management of chlordiazepoxide toxicity. Pharmacotherapy 20031101
Cerebral benzodiazepine receptors in depressed patients measured with [123I]iomazenil SPECT. Biological psychiatry 20031015
Biphasic action of midazolam on GABAA receptor-mediated responses in rat sacral dorsal commissural neurons. Biochemical and biophysical research communications 20031003
[Once more: the care duty of the physician in ambulatory administration of sedatives. Decision of the Federal Court, 4/8/2003-VI ZR 265/02]. Deutsche medizinische Wochenschrift (1946) 20031002
Extracts of kava (Piper methysticum) induce acute anxiolytic-like behavioral changes in mice. Psychopharmacology 20031001
Flumazenil attenuates development of tolerance to diazepam after chronic treatment of mice with either isoflurane or diazepam. Anesthesia and analgesia 20031001
An anxiolytic-like effect of Ginkgo biloba extract and its constituent, ginkgolide-A, in mice. Journal of natural products 20031001
Effect of zaleplon, a non-benzodiazepine hypnotic, on melatonin secretion in rabbits. Journal of pharmacological sciences 20031001
The new toy. JEMS : a journal of emergency medical services 20031001
Selective neuronal vulnerability following mild focal brain ischemia in the mouse. Brain pathology (Zurich, Switzerland) 20031001
Prediction of malignant course in MCA infarction by PET and microdialysis. Stroke 20030901
Receptor subtype-dependent positive and negative modulation of GABA(A) receptor function by niflumic acid, a nonsteroidal anti-inflammatory drug. Molecular pharmacology 20030901
[Sedation with intravenous midazolam during upper gastrointestinal endoscopy--changes in hemodynamics, oxygen saturation and memory]. Masui. The Japanese journal of anesthesiology 20030901
Hemoglobin metabolites mimic benzodiazepines and are possible mediators of hepatic encephalopathy. Blood 20030815
Flumazenil and tacrine increase the effectiveness of ondansetron on scopolamine-induced impairment of spatial learning in rats. Psychopharmacology 20030801
Propofol-induced anesthesia in mice is mediated by gamma-aminobutyric acid-A and excitatory amino acid receptors. Anesthesia and analgesia 20030801
Defibrillation efficacy and pain perception of two biphasic waveforms for internal cardioversion of atrial fibrillation. Journal of cardiovascular electrophysiology 20030801
Anxiolytic-like action of orally administered dl-tetrahydropalmatine in elevated plus-maze. Progress in neuro-psychopharmacology & biological psychiatry 20030801
Quantitative in vivo measurement of central benzodiazepine receptors in the brain of cats by use of positron-emission tomography and [11C]flumazenil. American journal of veterinary research 20030801
GABAergic inhibitory mechanisms for repetition-adaptivity in large-scale brain systems. NeuroImage 20030801
Studies on the anticonvulsant effect of U50488H on maximal electroshock seizure in mice. Pharmacology, biochemistry, and behavior 20030801
Semisynthetic preparation of amentoflavone: A negative modulator at GABA(A) receptors. Bioorganic & medicinal chemistry letters 20030721
Positron emission tomography in presurgical localization of epileptic foci. Ideggyogyaszati szemle 20030720
Drugs acting at the GABAA receptor attenuate ethanol-induced gastric mucosal damage in vitro. Clinical and experimental pharmacology & physiology 20030701
Novel one-pot one-step synthesis of 2'-[(18)F]fluoroflumazenil (FFMZ) for benzodiazepine receptor imaging. Nuclear medicine and biology 20030701
Physical dependence in baboons chronically treated with low and high doses of diazepam. Behavioural pharmacology 20030701
Characteristic brain distribution of 1-(14)C-octanoate in a rat model of focal cerebral ischemia in comparison with those of (123)I-IMP and (123)I-iomazenil. Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20030701
Extraction of epileptogenic foci from PET and SPECT images by fuzzy modeling and data fusion. NeuroImage 20030701
Attenuation of the effect of progesterone and 4'-chlordiazepam on stress-induced immune responses by bicuculline. Indian journal of physiology and pharmacology 20030701
Role of platelet activating factor in triazolobenzodiazepines-induced retrograde amnesia. Behavioural brain research 20030616
[Criminal use of psychoactive drugs. A cluster of 4 cases]. Medicina clinica 20030614
Involvement of presynaptic 5-HT(1A) and benzodiazepine receptors in the anticonflict activity of 5-HT(1A) receptor antagonists. European journal of pharmacology 20030613
Modification of morphine analgesia and tolerance by flumazenil in male and female rats. European journal of pharmacology 20030606
Grey and white matter flumazenil binding in neocortical epilepsy with normal MRI. A PET study of 44 patients. Brain : a journal of neurology 20030601
Flumazenil, a GABA antagonist, may improve features of Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society 20030601
Tail-swing behavior: a novel animal model for anxiety. Methods and findings in experimental and clinical pharmacology 20030601
NPI-031G (puerarin) reduces anxiogenic effects of alcohol withdrawal or benzodiazepine inverse or 5-HT2C agonists. Pharmacology, biochemistry, and behavior 20030601
The role of GABAB receptors in the discriminative stimulus effects of gamma-hydroxybutyrate in rats: time course and antagonism studies. The Journal of pharmacology and experimental therapeutics 20030501
Anxiogenic effects of neurosteroid exposure: sex differences and altered GABAA receptor pharmacology in adult rats. The Journal of pharmacology and experimental therapeutics 20030501
Potentiation of proopiomelanocortin gene expression in cultured pituitary cells by benzodiazepines. Anesthesiology 20030501
Anticonvulsant effect of flutamide on seizures induced by pentylenetetrazole: involvement of benzodiazepine receptors. Epilepsia 20030501
Flumazenil is innocuous in a paroxysmal supraventricular tachycardia and radiofrequency ablation: a paediatric case report and review of the literature. Paediatric anaesthesia 20030501
Flumazenil reverses a paradoxical reaction to intravenous midazolam in a child with uneventful prior exposure to midazolam. Paediatric anaesthesia 20030501
Anti-conflict-like actions of intralateral septal infusions of allopregnanolone in Wistar rats. Pharmacology, biochemistry, and behavior 20030501
Evaluation of the reinforcing and discriminative stimulus effects of 1,4-butanediol and gamma-butyrolactone in rhesus monkeys. European journal of pharmacology 20030411
Gamma-hydroxybutyric acid and diazepam antagonize a rapid increase in GABA(A) receptors alpha(4) subunit mRNA abundance induced by ethanol withdrawal in cerebellar granule cells. Molecular pharmacology 20030401
On the undecidability among kinetic models: from model selection to model averaging. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20030401
Flumazenil-induced ballism. Journal of Korean medical science 20030401
Anxiolytic-like effects of baicalein and baicalin in the Vogel conflict test in mice. European journal of pharmacology 20030319
Visualization of alpha5 subunit of GABAA/benzodiazepine receptor by 11C Ro15-4513 using positron emission tomography. Synapse (New York, N.Y.) 20030301
Gamma-aminobutyric acid neuropharmacological investigations on narcosis produced by nitrogen, argon, or nitrous oxide. Anesthesia and analgesia 20030301
Presurgical evaluation of epilepsy by brain diffusion: MR-detected effects of flumazenil on the epileptogenic focus. Epilepsia 20030301
Simple analytic method of 11C-flumazenil metabolite in blood. Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20030301
Inhibitory effect of propofol on ketamine-induced c-Fos expression in the rat posterior cingulate and retrosplenial cortices is mediated by GABAA receptor activation. Acta anaesthesiologica Scandinavica 20030301
Comparison of the cardiorespiratory effects of medetomidine-butorphanol-ketamine and medetomidine-butorphanol-midazolam in patas monkeys (Erythrocebus patas). Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians 20030301
Toxicity of intravenous anaesthetics. Best practice & research. Clinical anaesthesiology 20030301
The evaluation of cognitive function in the dementias: methodological and regulatory considerations. Dialogues in clinical neuroscience 20030301
The efficacy of flumazenil in subclinical to mild hepatic encephalopathic ambulatory patients. A prospective, randomised, double-blind, placebo-controlled study. Swiss medical weekly 20030222
[Poisonings with benzodiazepine-like drugs]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20030220
Flavonoid modulation of ionic currents mediated by GABA(A) and GABA(C) receptors. European journal of pharmacology 20030214
Structural requirements for imidazobenzodiazepine binding to GABA(A) receptors. Molecular pharmacology 20030201
The influence of midazolam and flumazenil on rat brain slices oxygen consumption. Pharmacological research 20030201
The GABA(A) receptor mediates the hypnotic activity of melatonin in rats. Pharmacology, biochemistry, and behavior 20030201
Effects of diazepam and flumazenil on food competition behavior in high- and low-aggression pigeons. Pharmacology, biochemistry, and behavior 20030201
Is central benzodiazepine receptor imaging useful for the identification of epileptogenic foci in localization-related epilepsies? European journal of nuclear medicine and molecular imaging 20030201
Modulation of inhibitory autapses and synapses on rat CA1 interneurones by GABA(A) receptor ligands. The Journal of physiology 20030201
The effect of diazepam on motor cortical oscillations and corticomuscular coherence studied in man. The Journal of physiology 20030201
Flumazenil reversal of lorazepam-induced acute delirium. The Journal of emergency medicine 20030201
Pharmacological evaluation of (S)-8-[123I]iodobretazenil: a radioligand for in vivo studies of central benzodiazepine receptors. Nuclear medicine and biology 20030201
Hepatic encephalopathy: nomenclature, pathogenesis and treatment. Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva 20030201
Are there teratogenic risks associated with antidotes used in the acute management of poisoned pregnant women? Birth defects research. Part A, Clinical and molecular teratology 20030201
[18F]FMDAA1106 and [18F]FEDAA1106: two positron-emitter labeled ligands for peripheral benzodiazepine receptor (PBR). Bioorganic & medicinal chemistry letters 20030120
Immobilization stress-induced increment of lactate metabolism in the basolateral amygdaloid nucleus is attenuated by diazepam in the rat. European journal of pharmacology 20030117
Prior exposure to the elevated plus-maze sensitizes mice to the acute behavioral effects of fluoxetine and phenelzine. European journal of pharmacology 20030117
Ginsenoside Rf potentiates U-50,488H-induced analgesia and inhibits tolerance to its analgesia in mice. Life sciences 20030103
Stereoselective discriminative stimulus effects of zopiclone in rhesus monkeys. Psychopharmacology 20030101
Effects of cholecystokinin tetrapeptide (CCK(4)) and of anxiolytic drugs on GABA outflow from the cerebral cortex of freely moving rats. Neurochemistry international 20030101
Comment on the paper by Horowski and Dorow. Psychopharmacology 20030101
Possible mechanism involved in the anticonvulsant action of butorphanol in mice. Pharmacology, biochemistry, and behavior 20030101
Discriminative stimulus effects of positive GABAA modulators and other anxiolytics, sedatives, and anticonvulsants in untreated and diazepam-treated monkeys. The Journal of pharmacology and experimental therapeutics 20030101
Flumazenil and dialysis for gabapentin-induced coma. The Annals of pharmacotherapy 20030101
Review: flumazenil leads to clinical and electroencephalographic improvement in hepatic encephalopathy in patients with cirrhosis. ACP journal club 20030101
Studies of peripheral benzodiazepine receptors in mussels: comparison between a polluted and a nonpolluted site. Ecotoxicology and environmental safety 20030101
Panic-related responses to pentagastrin, flumazenil, and thyrotropin-releasing hormone in healthy volunteers. Depression and anxiety 20030101
Adenosine A1 and benzodiazepine receptors and glucose metabolism in the visual structures of rats monocularly deprived by enucleation or eyelid suture at a sensitive period. Japanese journal of ophthalmology 20030101
[Acute pharmacologic poisoning (I). Psychotropic and antiarrhythmic drugs]. Anales del sistema sanitario de Navarra 20030101
Poisons: initial assessment and management. Clinical medicine (London, England) 20030101
Poisons: initial assessment and management. Clinical medicine (London, England) 20030101
Effect of ergot alkaloids on 3H-flunitrazepam binding to mouse brain GABAA receptors. Collegium antropologicum 20030101
An in vitro assay for predicting successful imaging radiotracers. Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 20030101
Image-derived input function for [11C]flumazenil kinetic analysis in human brain. Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 20030101
The effects of flumazenil on the antinociceptive actions of morphine in rats. Receptors & channels 20030101
PET neuroreceptor imaging as predictor of severe cerebral ischemic insult. Acta neurochirurgica. Supplement 20030101
Identification of malignant brain edema after hemispheric stroke by PET-imaging and microdialysis. Acta neurochirurgica. Supplement 20030101
National survey of the use of sedating drugs, neuromuscular blocking agents, and reversal agents in the intensive care unit. Journal of intensive care medicine 20030101
Identification of the bovine gamma-aminobutyric acid type A receptor alpha subunit residues photolabeled by the imidazobenzodiazepine [3H]Ro15-4513. The Journal of biological chemistry 20021220
Benzodiazepine receptor ligands. 7. Synthesis and pharmacological evaluation of new 3-esters of the 8-chloropyrazolo[5,1-c][1,2,4]benzotriazine 5-oxide. 3-(2-Thienylmethoxycarbonyl) derivative: an anxioselective agent in rodents. Journal of medicinal chemistry 20021219
Accidental bromazepam intoxication in a dog. The Veterinary record 20021207
Inhibitory effect of diazepam on muscarinic receptor-stimulated inositol 1,4,5-trisphosphate production in rat parotid acinar cells. British journal of pharmacology 20021201
Experience with 123I-iomazenil SPECT in acute cerebral infarction. Nuclear medicine communications 20021201
Flumazenil reduces midazolam-induced cognitive impairment without altering pharmacokinetics. Clinical pharmacology and therapeutics 20021201
Effect of flumazenil on GABAA receptors in isolated rat hippocampal neurons. Neurochemical research 20021201
Human models as tools in the development of psychotropic drugs. Dialogues in clinical neuroscience 20021201
GABA(A) receptor antagonists enhance cortical acetylcholine release induced by 5-HT(3) receptor blockade in freely moving rats. Brain research 20021122
Benzodiazepine receptors in the medial-posterior hypothalamus mediate the reduction of hippocampal theta frequency by chlordiazepoxide. Brain research 20021108
The beta subunit determines the ion selectivity of the GABAA receptor. The Journal of biological chemistry 20021101
5-ethoxymethyl-7-fluoro-3-oxo-1,2,3,5-tetrahydrobenzo[4,5]imidazo[1,2a]pyridine-4-N-(2-fluorophenyl)carboxamide (RWJ-51204), a new nonbenzodiazepine anxiolytic. The Journal of pharmacology and experimental therapeutics 20021101
Anxiolytic effect of wogonin, a benzodiazepine receptor ligand isolated from Scutellaria baicalensis Georgi. Biochemical pharmacology 20021101
Selective antagonism of the ataxic effects of zolpidem and triazolam by the GABAA/alpha1-preferring antagonist beta-CCt in squirrel monkeys. Psychopharmacology 20021101
The correlation between cerebral glucose metabolism and benzodiazepine receptor density in the acute vegetative state. European journal of neurology 20021101
No more coma cocktails. Using science to dispel myths & improve patient care. JEMS : a journal of emergency medical services 20021101
Effects of GABA(A) compounds on mCPP drug discrimination in rats. Life sciences 20021018
Flumazenil recovers diaphragm muscle dysfunction caused by midazolam in dogs. Anesthesia and analgesia 20021001
Evaluation of the reference tissue models for PET and SPECT benzodiazepine binding parameters. NeuroImage 20021001
Central-nervous side effects of midazolam during transesophageal echocardiography. Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography 20021001
Flumazenil antagonizes respiratory depression caused by diazepam and induces expiratory excitation of hypoglossal nerve. Masui. The Japanese journal of anesthesiology 20021001
Emergency drugs. Dental clinics of North America 20021001
Modulation of development of tolerance to anticonvulsant effect of diazepam by flumazenil. Indian journal of physiology and pharmacology 20021001
Intravenous flumazenil versus oxazepam tapering in the treatment of benzodiazepine withdrawal: a randomized, placebo-controlled study. Addiction biology 20021001
The anxiolytic action of mGlu2/3 receptor agonist, LY354740, in the fear-potentiated startle model in rats is mechanistically distinct from diazepam. Pharmacology, biochemistry, and behavior 20020901
A randomised, controlled trial of cognitive and psychomotor recovery from midazolam sedation following reversal with oral flumazenil. Anaesthesia 20020901
Quantitative analysis of benzodiazepine receptor in temporal lobe epilepsy: [(125)I]iomazenil autoradiographic study of surgically resected specimens. Epilepsia 20020901
Transport of amentoflavone across the blood-brain barrier in vitro. Planta medica 20020901
Mechanisms of anabolic androgenic steroid modulation of alpha(1)beta(3)gamma(2L) GABA(A) receptors. Neuropharmacology 20020901
Progesterone withdrawal increases the alpha4 subunit of the GABA(A) receptor in male rats in association with anxiety and altered pharmacology - a comparison with female rats. Neuropharmacology 20020901
[Recurrent idiopathic stupor in a patient: responsibility of exogenous or endogenous benzodiazepines?]. Revue neurologique 20020901
Diazepam withdrawal-induced anxiety and place aversion in the rat: differential effects of two chronic diazepam treatment regimes. Behavioural pharmacology 20020901
Temporal pole MRI abnormalities in temporal lobe epilepsy. Epileptic disorders : international epilepsy journal with videotape 20020901
Pathophysiological aspects of diversity in neuronal inhibition: a new benzodiazepine pharmacology. Dialogues in clinical neuroscience 20020901
Influence of different neural systems on the secretion of sex hormones in potassium deficient mice. Life sciences 20020816
The heterogeneity of central benzodiazepine receptor subtypes in the human hippocampal formation, frontal cortex and cerebellum using [3H]flumazenil and zolpidem. Brain research. Molecular brain research 20020815
Reversal of benzodiazepine-induced renal vasculature relaxation with flumazenil. European journal of pharmacology 20020802
Midazolam induces expression of c-Fos and EGR-1 by a non-GABAergic mechanism. Anesthesia and analgesia 20020801
Positron emission tomography partial volume correction: estimation and algorithms. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20020801
Gaba-benzodiazepine receptor complex in brain oxidative metabolism regulation. Pharmacological research 20020801
Flumazenil in acute benzodiazepine overdose. The Journal of the Association of Physicians of India 20020801
The anti-epileptic drug levetiracetam reverses the inhibition by negative allosteric modulators of neuronal GABA- and glycine-gated currents. British journal of pharmacology 20020701
Anesthesia-induced alterations in plasma tracer concentrations may have relevance for brain imaging studies. Anesthesiology 20020701
Imaging the GABA-benzodiazepine receptor subtype containing the alpha5-subunit in vivo with [11C]Ro15 4513 positron emission tomography. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20020701
[The changes of bispectral index induced by administration of midazolam during propofol anesthesia]. Masui. The Japanese journal of anesthesiology 20020701
Tonic immobility in guinea pigs: a behavioural response for detecting an anxiolytic-like effect? Behavioural pharmacology 20020701
GABA(A)-benzodiazepine receptor complex sensitivity in 5-HT(1A) receptor knockout mice on a 129/Sv background. European journal of pharmacology 20020628
Hypnotic effects of total aqueous extracts of Vervain hastata (Verbenaceae) in rats. Psychiatry and clinical neurosciences 20020601
The effect of intravenous administration of variable-dose flumazenil after fixed-dose ketamine and midazolam in healthy cats. Journal of veterinary pharmacology and therapeutics 20020601
Participation of GABAA receptors in the modulation of experimental anxiety by tachykinin agonists and antagonists in mice. Progress in neuro-psychopharmacology & biological psychiatry 20020601
Cardiorespiratory effects of medetomidine-butorphanol, medetomidine-butorphanol-diazepam, and medetomidine-butorphanol-ketamine in captive red wolves (Canis rufus). Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians 20020601
[Effect of flumazenil on the regional cerebral blood flow measured by [15O]-butanol PET scan and transcranial Doppler ultrasonography]. Orvosi hetilap 20020526
Effects of striatal injections of GABA(A) receptor agonists and antagonists in a genetic animal model of paroxysmal dystonia. European journal of pharmacology 20020517
GABAA-benzodiazepine receptor complex ligands and stress-induced hyperthermia in singly housed mice. Pharmacology, biochemistry, and behavior 20020501
3beta -hydroxypregnane steroids are pregnenolone sulfate-like GABA(A) receptor antagonists. The Journal of neuroscience : the official journal of the Society for Neuroscience 20020501
Short-term effects of intravenous benzodiazepines on autonomic neurocardiac regulation in humans: a comparison between midazolam, diazepam, and lorazepam. Critical care medicine 20020501
Is transient global amnesia related to endogenous benzodiazepines? Journal of neurology 20020501
125I-iomazenil-benzodiazepine receptor binding during psychological stress in rats. Annals of nuclear medicine 20020501
Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells. The Journal of biological chemistry 20020419
Evaluation of immunomodulatory potential of Ocimum sanctum seed oil and its possible mechanism of action. Journal of ethnopharmacology 20020401
Diazepam potentiates the effects of endogenous catecholamines on contractility and cyclic AMP levels in rat ventricular myocardium. Naunyn-Schmiedeberg's archives of pharmacology 20020401
Free-choice ethanol consumption under the influence of GABAergic drugs in rats. Alcoholism, clinical and experimental research 20020401
Partial antagonism of tiletamine-zolazepam anesthesia in cheetah. Journal of wildlife diseases 20020401
A randomised crossover trial of post-operative cognitive and psychomotor recovery from benzodiazepine sedation: effects of reversal with flumazenil over a prolonged recovery period. British dental journal 20020323
Daily treatment with diazepam differentially modifies sensitivity to the effects of gamma-aminobutyric acid(A) modulators on schedule-controlled responding in rhesus monkeys. The Journal of pharmacology and experimental therapeutics 20020301
Flumazenil vs. placebo in hepatic encephalopathy in patients with cirrhosis: a meta-analysis. Alimentary pharmacology & therapeutics 20020301
Impaired benzodiazepine receptor binding in peri-lesional cortex of patients with symptomatic epilepsies studied by [(11)C]-flumazenil PET. European journal of neurology 20020301
Provision of cues to signal a withdrawal US prevents the US pre-exposure effect in a diazepam-withdrawal conditioned taste aversion. Psychopharmacology 20020301
The effects of neuroleptics on the GABA-induced Cl- current in rat dorsal root ganglion neurons: differences between some neuroleptics. British journal of pharmacology 20020301
Does 5-HT restrain panic? A tryptophan depletion study in panic disorder patients recovered on paroxetine. Journal of psychopharmacology (Oxford, England) 20020301
Role of benzodiazepine-GABAA receptor complex in attenuation of U-50,488H-induced analgesia and inhibition of tolerance to its analgesia by ginseng total saponin in mice. Life sciences 20020301
New developments in the therapy of intoxications. Toxicology letters 20020227
Mechanism of alpha-subunit selectivity of benzodiazepine pharmacology at gamma-aminobutyric acid type A receptors. European journal of pharmacology 20020215
Discriminative stimulus effects of benzodiazepine (BZ)(1) receptor-selective ligands in rhesus monkeys. The Journal of pharmacology and experimental therapeutics 20020201
[(3)H]Flumazenil binding in the human hippocampal formation, frontal cortex and cerebellum detected by high-resolution phosphorimaging. Brain research 20020201
Use of dynamic negative airway pressure (DNAP) to assess sedative-induced upper airway obstruction. Anesthesiology 20020201
Accidental ingestion of alprazolam in 415 dogs. Veterinary and human toxicology 20020201
Insular cortex involvement in mesiotemporal lobe epilepsy: a positron emission tomography study. Annals of neurology 20020201
Diazepam binding inhibitor (DBI) reduces testosterone and estradiol levels in vivo. Life sciences 20020201
Nociceptin and dynorphin A(1-17) produce antianalgesia through independent systems in mice. Life sciences 20020118
Binding and neuropharmacological profile of zaleplon, a novel nonbenzodiazepine sedative/hypnotic. European journal of pharmacology 20020102
Role of the histidine residue at position 105 in the human alpha 5 containing GABA(A) receptor on the affinity and efficacy of benzodiazepine site ligands. British journal of pharmacology 20020101
Modulation of radioligand binding to the GABA(A)-benzodiazepine receptor complex by a new component from Cyperus rotundus. Biological & pharmaceutical bulletin 20020101
Flumazenil responsive ornithine transcarbamylase deficiency encephalopathy: clinical and radiographic features. Journal of neuroimaging : official journal of the American Society of Neuroimaging 20020101
Mechanism of respiratory insufficiency in pure or mixed drug-induced coma involving benzodiazepines. Journal of toxicology. Clinical toxicology 20020101
Midazolam sedation for upper gastrointestinal endoscopy: comparison between the states of patients in partial and complete amnesia. Hepato-gastroenterology 20020101
Role of nitric oxide in benzodiazepines-induced antinociception in mice. Polish journal of pharmacology 20020101
Identification of critical residues in loop E in the 5-HT3ASR binding site. BMC biochemistry 20020101
[Chloral hydrate: a hypnotic best forgotten?]. L'Encephale 20020101
Zaleplon-induced coma and bluish-green urine: possible antidotal effect by flumazenil. Journal of toxicology. Clinical toxicology 20020101
[Therapeutic management of hepatic encephalopathy]. Wiadomosci lekarskie (Warsaw, Poland : 1960) 20020101
TREC-Rio trial: a randomised controlled trial for rapid tranquillisation for agitated patients in emergency psychiatric rooms [ISRCTN44153243]. BMC psychiatry 20020101
Blockade of gamma-aminobutyric acid receptors does not modify the inhibiton of ethanol intake induced by Hypericum perforatum in rats. Alcohol and alcoholism (Oxford, Oxfordshire) 20020101
Cerebral blood perfusion after treatment with zolpidem and flumazenil in the baboon. Arzneimittel-Forschung 20020101
Differential effects of benzodiazepines on immune responses in non-stressed and stressed animals. Indian journal of medical sciences 20020101
Paradoxical reactions to benzodiazepines in intravenous sedation: a report of 2 cases and review of the literature. Anesthesia progress 20020101
Flumazenil reduces the hypnotic dose of propofol in male patients under spinal anesthesia. Journal of anesthesia 20020101
[Chronic liver diseases. The nihilism has gone]. MMW Fortschritte der Medizin 20011213
Binding of [3H]CB 34, a selective ligand for peripheral benzodiazepine receptors, to rat brain membranes. European journal of pharmacology 20011207
Involvement of benzodiazepine binding sites in an antiaggressive effect by 5-HT(1A) receptor activation in isolated mice. European journal of pharmacology 20011207
Brain function in social anxiety disorder. The Psychiatric clinics of North America 20011201
The midazolam-induced paradox phenomenon is reversible by flumazenil. Epidemiology, patient characteristics and review of the literature. European journal of anaesthesiology 20011201
Chronic benzodiazepine treatment of cells expressing recombinant GABA(A) receptors uncouples allosteric binding: studies on possible mechanisms. Journal of neurochemistry 20011201
Dual-[11C]tracer single-acquisition positron emission tomography studies. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20011201
Delayed synaptic dysfunction of association cortices in carbon monoxide intoxication. Annals of neurology 20011201
Effects of harmine on dopamine output and metabolism in rat striatum: role of monoamine oxidase-A inhibition. Psychopharmacology 20011201
Effect of diazepam binding inhibitor (DBI) on the fluid intake, preference and the taste reactivity in mice. Behavioural brain research 20011129
[Functional imaging (PET and SPECT) in epilepsy]. Orvosi hetilap 20011104
Confluence of antianalgesic action of diverse agents through brain interleukin(1beta) in mice. The Journal of pharmacology and experimental therapeutics 20011101
Flumazenil improves cognitive and neuromotor emergence and attenuates shivering after halothane-, enflurane- and isoflurane-based anesthesia. Canadian journal of anaesthesia = Journal canadien d'anesthesie 20011101
The negative GABA(A) modulator methyl beta-carboline-3-carboxylate attenuates the behavioral effects of the positive GABA(A) modulators triazolam and pregnanolone in rhesus monkeys. Psychopharmacology 20011101
Nutritional parameters modify muricidal behavior of male Wistar rats: preventive effects of amino acids and 4' Cl diazepam. Life sciences 20011026
Synergistic interaction of diazepam with 3',5'-cyclic adenosine monophosphate-elevating agents on rat aortic rings. European journal of pharmacology 20011005
2-Arylpyrazolo[1,5-a]pyrimidin-3-yl acetamides. New potent and selective peripheral benzodiazepine receptor ligands. Bioorganic & medicinal chemistry 20011001
A change in the density of [(3)H]flumazenil, but not [(3)H]muscimol binding, in Brodmann's Area 9 from subjects with bipolar disorder. Journal of affective disorders 20011001
Biodistribution, binding specificity and metabolism of [18F]fluoroethylflumazenil in rodents. Nuclear medicine and biology 20011001
[18F]Fluoroethylflumazenil: a novel tracer for PET imaging of human benzodiazepine receptors. European journal of nuclear medicine 20011001
[Tetraplegia in the course of coma from drug intoxication]. Annales francaises d'anesthesie et de reanimation 20011001
Prolonged vigabatrin treatment modifies developmental changes of GABA(A)-receptor binding in young children with epilepsy. Epilepsia 20011001
Benzodiazepine-GABA(A) receptor binding is very low in dysembryoplastic neuroepithelial tumor: a PET study. Epilepsia 20011001
Benzodiazepines in the intensive care unit. Critical care clinics 20011001
Possible mechanism of anticonvulsant effect of ketamine in mice. Indian journal of experimental biology 20011001
Anxiolytic effect of Kami-Shoyo-San (TJ-24) in mice: possible mediation of neurosteroid synthesis. Life sciences 20010921
Vesicular neurotransmitter transporters in Huntington's disease: initial observations and comparison with traditional synaptic markers. Synapse (New York, N.Y.) 20010915
Potency of positive gamma-aminobutyric acid(A) modulators to substitute for a midazolam discriminative stimulus in untreated monkeys does not predict potency to attenuate a flumazenil discriminative stimulus in diazepam-treated monkeys. The Journal of pharmacology and experimental therapeutics 20010901
SPECT and neuropsychological performance in severe depression treated with ECT. Journal of affective disorders 20010901
The effects of flumazenil, Ro 154513 and beta-CCM on the behaviour of control and stressed mice in the staircase test. Journal of psychopharmacology (Oxford, England) 20010901
Dose-dependent enhancement of in vivo GABA(A)-benzodiazepine receptor binding by isoflurane. Anesthesiology 20010901
Influence of benzodiazepine binding site ligands on fear-conditioned contextual memory. European journal of pharmacology 20010824
Increase in expression of the GABA(A) receptor alpha(4) subunit gene induced by withdrawal of, but not by long-term treatment with, benzodiazepine full or partial agonists. Brain research. Molecular brain research 20010815
Central benzodiazepine receptors in malformations of cortical development: A quantitative study. Brain : a journal of neurology 20010801
High-dose flumazenil potentiates the hypnotic activity of propofol, but not that of thiopental, in ddY mice. Acta anaesthesiologica Scandinavica 20010801
The effects of benzodiazepines on human opioid receptor binding and function. Anesthesia and analgesia 20010801
Changes in mACh, NMDA and GABA(A) receptor binding after lateral fluid-percussion injury: in vitro autoradiography of rat brain frozen sections. Journal of neurochemistry 20010801
Diazepam increases the hypothalamic-pituitary-adrenocortical (HPA) axis activity by a cyclic AMP-dependent mechanism. British journal of pharmacology 20010801
Different types of GABA(A) receptors may mediate the anticonflict and response rate-decreasing effects of zaleplon, zolpidem, and midazolam in squirrel monkeys. Psychopharmacology 20010801
Neurophysiological effects of an extract of Eschscholzia californica Cham. (Papaveraceae). Phytotherapy research : PTR 20010801
Benzodiazepines protect against ethanol-induced gastric mucosal damage in vitro. Fundamental & clinical pharmacology 20010801
The influences of extremely low frequency magnetic fields on clonidine-induced sleep in 2-day-old chicks. Journal of autonomic pharmacology 20010801
Sleep inducing effects of propofol microinjection into the medial preoptic area are blocked by flumazenil. Brain research 20010727
Availability of antidotes at acute care hospitals in Ontario. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20010710
Novel N-(arylalkyl)indol-3-ylglyoxylylamides targeted as ligands of the benzodiazepine receptor: synthesis, biological evaluation, and molecular modeling analysis of the structure-activity relationships. Journal of medicinal chemistry 20010705
A fluorescent receptor assay for benzodiazepines using coumarin-labeled desethylflumazenil as ligand. Analytical chemistry 20010701
Hepatic Encephalopathy. The American journal of gastroenterology 20010701
Case report of pallido-pyramidal disease with supplementary motor area involvement. Movement disorders : official journal of the Movement Disorder Society 20010701
Disturbed benzodiazepine receptor function at the onset of temporal lobe epilepsy--lomanzenil-binding in de-novo TLE. Journal of neurology 20010701
Flumazenil is a benzodiazepine receptor antagonist. Indian journal of physiology and pharmacology 20010701
Relationship of flumazenil and glucose PET abnormalities to neocortical epilepsy surgery outcome. Neurology 20010626
Reversal of reserpine-induced vacuous chewing movements in rats by melatonin: involvement of peripheral benzodiazepine receptors. Brain research 20010615
Behavioral effects of flunitrazepam: reinforcing and discriminative stimulus effects in rhesus monkeys and prevention of withdrawal signs in pentobarbital-dependent rats. Drug and alcohol dependence 20010601
Diazepam poisoning with one-month monitoring of diazepam and nordiazepam blood levels. Veterinary and human toxicology 20010601
The effects of flumazenil on sleepiness, task performance and nocturnal sleep after anesthesia with midazolam. Psychiatry and clinical neurosciences 20010601
A small dose of midazolam decreases the time to achieve hypnosis without delaying emergence during short-term propofol anesthesia. Journal of clinical anesthesia 20010601
Interactions between LY354740, a group II metabotropic agonist and the GABA(A)-benzodiazepine receptor complex in the rat elevated plus-maze. Journal of psychopharmacology (Oxford, England) 20010601
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