1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-1,8-naphthyridine-3-carboxylic acid
Title | Journal |
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Dysregulated miRNA biogenesis downstream of cellular stress and ALS-causing mutations: a new mechanism for ALS. | The EMBO journal 20151103 |
The role of muscle microRNAs in repairing the neuromuscular junction. | PloS one 20140101 |
FDA-approved drugs and other compounds tested as inhibitors of human glutathione transferase P1-1. | Chemico-biological interactions 20130905 |
Identification of old drugs as potential inhibitors of HIV-1 integrase - human LEDGF/p75 interaction via molecular docking. | Journal of molecular modeling 20121201 |
Emergence of resistance to fluoroquinolones among gram positive and gram negative clinical isolates. | Pakistan journal of pharmaceutical sciences 20121001 |
V-ATPases in osteoclasts: structure, function and potential inhibitors of bone resorption. | The international journal of biochemistry & cell biology 20120901 |
Development of a class-specific polyclonal antibody-based indirect competitive ELISA for detecting fluoroquinolone residues in milk. | Journal of Zhejiang University. Science. B 20120701 |
Occurrence and risks of antibiotics in the Laizhou Bay, China: impacts of river discharge. | Ecotoxicology and environmental safety 20120601 |
Enoxacin directly inhibits osteoclastogenesis without inducing apoptosis. | The Journal of biological chemistry 20120518 |
[A new pathogen of gibel carp Carassius auratus gibelio-Shewanella putrefaciens]. | Wei sheng wu xue bao = Acta microbiologica Sinica 20120504 |
DNA methylation-associated silencing of tumor-suppressor microRNAs in cancer. | Oncogene 20120329 |
Seeking to shed some light on the binding of fluoroquinolones to albumins. | The journal of physical chemistry. B 20120322 |
Novel oxoisoaporphine-based inhibitors of acetyl- and butyrylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation. | Bioorganic & medicinal chemistry letters 20120315 |
Rational identification of enoxacin as a novel V-ATPase-directed osteoclast inhibitor. | Current protein & peptide science 20120301 |
Small molecule inhibition of RISC loading. | ACS chemical biology 20120217 |
Simultaneous determination of fluoroquinolones in foods of animal origin by a high performance liquid chromatography and a liquid chromatography tandem mass spectrometry with accelerated solvent extraction. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120215 |
A small chemical library of 2-aminoimidazole derivatives as BACE-1 inhibitors: Structure-based design, synthesis, and biological evaluation. | European journal of medicinal chemistry 20120201 |
Spectroscopic and photophysical properties of protonated forms of some fluoroquinolones in solutions. | Journal of fluorescence 20120101 |
Neuroprotective efficacy of quinazoline type phosphodiesterase 7 inhibitors in cellular cultures and experimental stroke model. | European journal of medicinal chemistry 20120101 |
A sensitive chromatographic strip test for the rapid detection of enrofloxacin in chicken muscle. | Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20120101 |
Liquid chromatographic determination of quinolones in water and human urine samples after microextraction by packed sorbent. | Journal of AOAC International 20120101 |
Sudden death of cardiac origin and psychotropic drugs. | Frontiers in pharmacology 20120101 |
Spectroscopic studies on the lanthanide sensitized luminescence and chemiluminescence properties of fluoroquinolone with different structure. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20111101 |
Ionic liquid-based homogeneous liquid-liquid microextraction for the determination of antibiotics in milk by high-performance liquid chromatography. | Journal of chromatography. A 20111014 |
Hybrids of oxoisoaporphine-tacrine congeners: novel acetylcholinesterase and acetylcholinesterase-induced β-amyloid aggregation inhibitors. | European journal of medicinal chemistry 20111001 |
An insight into the drug resistance profile & mechanism of drug resistance in Neisseria gonorrhoeae. | The Indian journal of medical research 20111001 |
Ethyl 4-(phenyl-sulfon-yl)piperazine-1-carboxyl-ate. | Acta crystallographica. Section E, Structure reports online 20110901 |
N-acylaminophenothiazines: neuroprotective agents displaying multifunctional activities for a potential treatment of Alzheimer's disease. | European journal of medicinal chemistry 20110601 |
Evidence-based guidelines for empirical therapy of neutropenic fever in Korea. | The Korean journal of internal medicine 20110601 |
Effect of topoisomerase inhibitors and DNA-binding drugs on the cell proliferation and ultrastructure of Trypanosoma cruzi. | International journal of antimicrobial agents 20110501 |
C. elegans: model host and tool for antimicrobial drug discovery. | Disease models & mechanisms 20110501 |
Effect of enoxacin, felbinac, and sparfloxacin on fatty acid metabolism and glucose concentrations in rat tissues. | International journal of toxicology 20110501 |
Effect of steady-state enoxacin on single-dose pharmacokinetics of roflumilast and roflumilast N-oxide. | Journal of clinical pharmacology 20110401 |
A simple chromatographic method for determining norfloxacin and enoxacin in pharmacokinetic study assessing CYP1A2 inhibition. | Biomedical chromatography : BMC 20110401 |
Ethyl 4-[2-(3,5-dimethyl-4-oxo-2,6-diphenyl-piperidin-1-yl)-2-oxoeth-yl]piperazine-1-carboxyl-ate. | Acta crystallographica. Section E, Structure reports online 20110301 |
Quinolone compounds enhance delta-aminolevulinic acid-induced accumulation of protoporphyrin IX and photosensitivity of tumour cells. | Journal of biochemistry 20110201 |
Synthesis and evaluation of a class of new coumarin triazole derivatives as potential antimicrobial agents. | Bioorganic & medicinal chemistry letters 20110201 |
Integrative genome-scale metabolic analysis of Vibrio vulnificus for drug targeting and discovery. | Molecular systems biology 20110101 |
Diffusion of ofloxacin in the endocarditis vegetation assessed with synchrotron radiation UV fluorescence microspectroscopy. | PloS one 20110101 |
Lack of the delta subunit of RNA polymerase increases virulence related traits of Streptococcus mutans. | PloS one 20110101 |
No relevant cardiac, pharmacokinetic or safety interactions between roflumilast and inhaled formoterol in healthy subjects: an open-label, randomised, actively controlled study. | BMC clinical pharmacology 20110101 |
Mechanism and Function of the Outer Membrane Channel TolC in Multidrug Resistance and Physiology of Enterobacteria. | Frontiers in microbiology 20110101 |
[Safety profile of antimicrobial agents]. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20110101 |
RP-HPLC Method for Simultaneous Estimation of Nitazoxanide and Ofloxacin in Tablets. | Indian journal of pharmaceutical sciences 20110101 |
Induction of cytoplasmic rods and rings structures by inhibition of the CTP and GTP synthetic pathway in mammalian cells. | PloS one 20110101 |
Evaluation of antiproliferative activity of red sorghum bran anthocyanin on a human breast cancer cell line (mcf-7). | International journal of breast cancer 20110101 |
Local application of gentamicin collagen implants in the prophylaxis of surgical site infections following gastrointestinal surgery: a review of clinical experience. | Techniques in coloproctology 20101201 |
Comparative use of isolated hepatocytes and hepatic microsomes for cytochrome P450 inhibition studies: transporter-enzyme interplay. | Drug metabolism and disposition: the biological fate of chemicals 20101201 |
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. | Bioorganic & medicinal chemistry letters 20101101 |
Determination of enoxacin and ofloxacin by capillary electrophoresis with electrochemiluminescence detection in biofluids and drugs and its application to pharmacokinetics. | Biomedical chromatography : BMC 20100901 |
Once-daily gentamicin administration for community-associated methicillin resistant Staphylococcus aureus in an in vitro pharmacodynamic model: preliminary reports for the advantages for optimizing pharmacodynamic index. | Yonsei medical journal 20100901 |
Simultaneous determination of quinolones in fish by liquid chromatography coupled with fluorescence detection: comparison of sub-2 microm particles and conventional C18 columns. | Journal of separation science 20100701 |
Small molecule modifiers of microRNA miR-122 function for the treatment of hepatitis C virus infection and hepatocellular carcinoma. | Journal of the American Chemical Society 20100616 |
[Enoxacin for type III A prostatitis: a clinical observation]. | Zhonghua nan ke xue = National journal of andrology 20100301 |
Simultaneous determination of tetracaine, proline, and enoxacin in human urine by CE with ECL detection. | Journal of chromatographic science 20100101 |
Roflumilast: first phosphodiesterase 4 inhibitor approved for treatment of COPD. | Drug design, development and therapy 20100101 |
Biopsy proven acute interstitial nephritis after treatment with moxifloxacin. | BMC nephrology 20100101 |
An application of Ag(III) complex chemiluminescence system for the determination of enoxacin in capsule and biological fluid. | Drug testing and analysis 20100101 |
Quantitation of fluoroquinolones in honey using tandem mass spectrometry (LC-MS/MS): nested validation with two mass spectrometers. | Journal of AOAC International 20100101 |
Contamination of surface, ground, and drinking water from pharmaceutical production. | Environmental toxicology and chemistry 20091201 |
Neuroprotective and cholinergic properties of multifunctional glutamic acid derivatives for the treatment of Alzheimer's disease. | Journal of medicinal chemistry 20091126 |
Antimicrobial susceptibility and ESBL prevalence in Pseudomonas aeruginosa isolated from burn patients in the North West of Pakistan. | Burns : journal of the International Society for Burn Injuries 20091101 |
Identification of enoxacin as an inhibitor of osteoclast formation and bone resorption by structure-based virtual screening. | Journal of medicinal chemistry 20090827 |
Elevation of serum gamma-glutamyltranspeptidase activity is frequent in chronic hepatitis C, and is associated with insulin resistance. | Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20090801 |
7-((4-Substituted)piperazin-1-yl) derivatives of ciprofloxacin: synthesis and in vitro biological evaluation as potential antitumor agents. | Bioorganic & medicinal chemistry 20090801 |
Conformationally constrained analogs of N-substituted piperazinylquinolones: synthesis and antibacterial activity of N-(2,3-dihydro-4-hydroxyimino-4H-1-benzopyran-3-yl)-piperazinylquinolones. | Archiv der Pharmazie 20090701 |
Synthesis and biological evaluations of enoxacin carboxamide derivatives. | Archives of pharmacal research 20090701 |
Prevalence of lower urinary tract infection in South Indian type 2 diabetic subjects. | Indian journal of nephrology 20090701 |
Systematic review: impaired drug absorption related to the co-administration of antisecretory therapy. | Alimentary pharmacology & therapeutics 20090615 |
Tacripyrines, the first tacrine-dihydropyridine hybrids, as multitarget-directed ligands for the treatment of Alzheimer's disease. | Journal of medicinal chemistry 20090514 |
Evaluation of Pharmasolve corneal permeability enhancement and its irritation on rabbit eyes. | Drug delivery 20090501 |
Fluoroquinolones reduce carrageenan-induced edema in rats and the involvement of the glucocorticoid receptor system. | Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20090401 |
N-Substituted piperazinyl quinolones as potential cytotoxic agents: structure-activity relationships study. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20090301 |
Natural history of small gallbladder polyps is benign: evidence from a clinical and pathogenetic study. | The American journal of gastroenterology 20090301 |
Rapid determination of 19 quinolone residues in spiked fish and pig muscle by high-performance liquid chromatography (HPLC) tandem mass spectrometry. | Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20090301 |
Dysprosium-sensitized chemiluminescence system for the determination of enoxacin in pharmaceutical preparations and biological fluids with flow-injection sampling. | Drug testing and analysis 20090301 |
Selective sample preparation for the analysis of (fluoro)quinolones in baby food: molecularly imprinted polymers versus anion-exchange resins. | Analytical and bioanalytical chemistry 20090201 |
Spectrofluorimetric determination of fluoroquinolones in pharmaceutical preparations. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20090201 |
Functional characterization of multidrug and toxin extrusion protein 1 as a facilitative transporter for fluoroquinolones. | The Journal of pharmacology and experimental therapeutics 20090201 |
Studies of the photooxidant properties of antibacterial fluoroquinolones and their naphthalene derivatives. | Die Pharmazie 20090201 |
CE determination of quinolones in the presence of bovine serum albumin. | Journal of separation science 20090101 |
Quantitative comparison of the convulsive activity of combinations of twelve fluoroquinolones with five nonsteroidal antiinflammatory agents. | Drug metabolism and pharmacokinetics 20090101 |
A comparison of fluoroquinolones versus other antibiotics for treating enteric fever: meta-analysis. | BMJ (Clinical research ed.) 20090101 |
Synthesis, characterization, antibacterial and anti-inflammatory activities of enoxacin metal complexes. | Bioinorganic chemistry and applications 20090101 |
Regulation of MicroRNA Biogenesis: A miRiad of mechanisms. | Cell communication and signaling : CCS 20090101 |
Identification of antifungal compounds active against Candida albicans using an improved high-throughput Caenorhabditis elegans assay. | PloS one 20090101 |
A seizure attributed to ofloxacine in a woman undergoing detoxification for alcohol dependence. | Case reports in medicine 20090101 |
Semiconductor quantum dots in chemical sensors and biosensors. | Sensors (Basel, Switzerland) 20090101 |
Trace analysis of quinolone and fluoroquinolone antibiotics from wastewaters by liquid chromatography-electrospray tandem mass spectrometry. | Journal of chromatography. A 20081219 |
Effects of treatment with antimicrobial agents on the human colonic microflora. | Therapeutics and clinical risk management 20081201 |
Enhancement of RNAi by a small molecule antibiotic enoxacin. | Cell research 20081001 |
Formation of secondary triplet species after excitation of fluoroquinolones in the presence of relatively strong bases. | Journal of the American Chemical Society 20080917 |
Determination of enoxacin using Tb composite nanoparticles sensitized luminescence method. | Journal of fluorescence 20080901 |
A small molecule enhances RNA interference and promotes microRNA processing. | Nature biotechnology 20080801 |
Development of an immunochromatography strip for the rapid detection of 12 fluoroquinolones in chicken muscle and liver. | Journal of agricultural and food chemistry 20080723 |
Drug resistance mechanism of the fish-pathogenic bacterium Lactococcus garvieae. | Journal of fish diseases 20080601 |
Exploring Mn-doped ZnS quantum dots for the room-temperature phosphorescence detection of enoxacin in biological fluids. | Analytical chemistry 20080515 |
In vivo methods for the assessment of topical drug bioavailability. | Pharmaceutical research 20080101 |
Synthesis and antibacterial activity of quinolone-based compounds containing a coumarin moiety. | Archiv der Pharmazie 20080101 |
Development of an HPLC multi-residue method for the determination of ten quinolones in bovine liver and porcine kidney according to the European Union Decision 2002/657/EC. | Journal of separation science 20080101 |
Utility of a single adjusting compartment: a novel methodology for whole body physiologically-based pharmacokinetic modelling. | Theoretical biology & medical modelling 20080101 |
Predictive analysis of transmissible quinolone resistance indicates Stenotrophomonas maltophilia as a potential source of a novel family of Qnr determinants. | BMC microbiology 20080101 |
Bitter taste receptors influence glucose homeostasis. | PloS one 20080101 |
Effect of physiological heterogeneity of E. coli population on antibiotic susceptivity test. | Science in China. Series C, Life sciences 20071201 |
Development and validation of an HPLC confirmatory method for residue analysis of ten quinolones in tissues of various food-producing animals, according to the European Union Decision 2002/657/EC. | Journal of separation science 20071101 |
A rapid CE-potential gradient detection method for determination of quinolones. | Electrophoresis 20071101 |
In vitro cytotoxicity and phototoxicity of N-piperazinyl quinolone derivatives with a 2-thienyl group. | Toxicology in vitro : an international journal published in association with BIBRA 20070901 |
Leishmania panamensis: comparative inhibition of nuclear DNA topoisomerase II enzymes from promastigotes and human macrophages reveals anti-parasite selectivity of fluoroquinolones, flavonoids and pentamidine. | Experimental parasitology 20070801 |
In vitro availability studies of enoxacin in presence of H2 receptor antagonists. | Pakistan journal of pharmaceutical sciences 20070701 |
Exploiting amoeboid and non-vertebrate animal model systems to study the virulence of human pathogenic fungi. | PLoS pathogens 20070701 |
[Determination of 16 quinolone residues in animal tissues using high performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry]. | Se pu = Chinese journal of chromatography 20070701 |
Triplet excited fluoroquinolones as mediators for thymine cyclobutane dimer formation in DNA. | The journal of physical chemistry. B 20070628 |
Effective separation and simultaneous determination of seven fluoroquinolones by capillary electrophoresis with diode-array detector. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070601 |
Separation of fifteen quinolones by high performance liquid chromatography: application to pharmaceuticals and ofloxacin determination in urine. | Journal of separation science 20070601 |
Determination of fluorinated quinolone antibacterials by ion chromatography with fluorescence detection. | Journal of Zhejiang University. Science. B 20070501 |
Enoxacin-Tb3+ complex as an environmentally friendly fluorescence probe for DNA and its application. | Talanta 20070215 |
Induction of keratinocyte apoptosis by photosensitizing chemicals plus UVA. | Journal of dermatological science 20070201 |
Antifungal chemical compounds identified using a C. elegans pathogenicity assay. | PLoS pathogens 20070201 |
UV-Vis spectrophotometrical and analytical methodology for the determination of singlet oxygen in new antibacterials drugs. | Analytical chemistry insights 20070101 |
Interaction between fluoroquinolones and bovine serum albumin studied by affinity capillary electrophoresis. | Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20061201 |
Micro- and nanofabrication methods in nanotechnological medical and pharmaceutical devices. | International journal of nanomedicine 20061201 |
A new approach to quantitative NMR: fluoroquinolones analysis by evaluating the chemical shift displacements. | Journal of pharmaceutical and biomedical analysis 20061011 |
Investigation on sensitized chemiluminescence systems and their mechanism for five fluoroquinolones. | Analytica chimica acta 20060825 |
Interference-free determination of fluoroquinolone antibiotics in plasma by using excitation-emission matrix fluorescence coupled with second-order calibration algorithms. | Talanta 20060815 |
Quinolones for uncomplicated acute cystitis in women. | The Cochrane database of systematic reviews 20060719 |
Synthesis and antibacterial activity of new fluoroquinolones containing a substituted N-(phenethyl)piperazine moiety. | Bioorganic & medicinal chemistry letters 20060701 |
A batch chemiluminescence determination of enoxacin using a tris-(1,10-phenanthroline)ruthenium(II)-cerium(IV) system. | Journal of fluorescence 20060701 |
Electrochemiluminescence of terbium (III)-two fluoroquinolones-sodium sulfite system in aqueous solution. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20060501 |
Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 |
Simultaneous determination of (fluoro)quinolone antibiotics in kidney, marine products, eggs, and muscle by enzyme-linked immunosorbent assay (ELISA). | Journal of agricultural and food chemistry 20060419 |
Mutagenesis induced by 12 quinolone antibacterial agents in Escherichia coli WP2uvrA/pKM101. | Toxicology in vitro : an international journal published in association with BIBRA 20060401 |
Effect of fluoroquinolones on plasma glucose levels in fasted and glucose-loaded mice. | Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20060401 |
[Study on interaction of caffeine and theophylline with bovine serum albumins]. | Guang pu xue yu guang pu fen xi = Guang pu 20060301 |
Genotoxic potential of quinolone antimicrobials in the in vitro comet assay and micronucleus test. | Mutation research 20060227 |
Determination of fluoroquinolones in urine and serum by using high performance liquid chromatography and multiemission scan fluorimetric detection. | Talanta 20060215 |
Antimicrobial drug resistance, regulation, and research. | Emerging infectious diseases 20060201 |
Photophysics and photochemistry of nalidixic acid. | Photochemistry and photobiology 20060101 |
T cell-mediated hypersensitivity to quinolones: mechanisms and cross-reactivity. | Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20060101 |
Effects of Transcutol P on the corneal permeability of drugs and evaluation of its ocular irritation of rabbit eyes. | The Journal of pharmacy and pharmacology 20060101 |
Radiation-induced in vitro phototoxic potential of some fluoroquinolones. | Drug and chemical toxicology 20060101 |
Preparation and evaluation of sustained ophthalmic gel of enoxacin. | Drug development and industrial pharmacy 20051201 |
Validation of a novel HPLC sorbent material for the determination of ten quinolones in human and veterinary pharmaceutical formulations. | Journal of separation science 20051201 |
Selective action of fluoroquinolones against intracellular amastigotes of Leishmania (Viannia) panamensis in vitro. | The Journal of parasitology 20051201 |
Separation and determination of seven fluoroquinolones by pressurized capillary electrochromatography. | Journal of separation science 20051101 |
[Determination of enoxacin in urine by synchronous fluorimetry]. | Guang pu xue yu guang pu fen xi = Guang pu 20051001 |
HPLC determination of enoxacin, ciprofloxacin, norfloxacin and ofloxacin with photoinduced fluorimetric (PIF) detection and multiemission scanning: application to urine and serum. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050805 |
Structure-phototoxicity relationship in Balb/c mice treated with fluoroquinolone derivatives, followed by ultraviolet-A irradiation. | Toxicology letters 20050704 |
Interaction study between enoxacin and fluvoxamine. | Therapeutic drug monitoring 20050601 |
Prediction of genotoxicity of chemical compounds by statistical learning methods. | Chemical research in toxicology 20050601 |
Vibrational spectroscopic characterization of fluoroquinolones. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20050501 |
Susceptibility and resistance genes to fluoroquinolones in methicillin-resistant Staphylococcus aureus isolated in 2002. | International journal of antimicrobial agents 20050501 |
Fluoroquinolone-resistant Campylobacter isolates from conventional and antibiotic-free chicken products. | Environmental health perspectives 20050501 |
Antimicrosporidial activity of (fluoro)quinolones in vitro and in vivo. | Folia parasitologica 20050501 |
Evaluation of phototoxic and photoallergic potentials of 13 compounds by different in vitro and in vivo methods. | Journal of photochemistry and photobiology. B, Biology 20050404 |
Determination of fluoroquinolones in edible animal tissue samples by high performance liquid chromatography after solid phase extraction. | Journal of separation science 20050401 |
Antibacterial studies, DNA oxidative cleavage, and crystal structures of Cu(II) and Co(II) complexes with two quinolone family members, ciprofloxacin and enoxacin. | Journal of inorganic biochemistry 20050301 |
Direct determination of five fluoroquinolones in chicken whole blood and in veterinary drugs by HPLC. | Journal of separation science 20050301 |
Celecoxib does not induce convulsions nor does it affect GABAA receptor binding activity in the presence of new quinolones in mice. | European journal of pharmacology 20050110 |
Induced and photoinduced DNA damage by quinolones: ciprofloxacin, ofloxacin and nalidixic acid determined by comet assay. | Photochemistry and photobiology 20050101 |
Flow-injection electrogenerated chemiluminescence determination of fluoroquinolones based on its sensitizing effect. | Luminescence : the journal of biological and chemical luminescence 20050101 |
A novel approach to estimate in vitro antibacterial potency of Chinese medicine using a concentration-killing curve method. | The American journal of Chinese medicine 20050101 |
Bench-to-bedside review: antimicrobial utilization strategies aimed at preventing the emergence of bacterial resistance in the intensive care unit. | Critical care (London, England) 20050101 |
Validation of HPLC method for determination of six fluoroquinolones: cinoxacin, ciprofloxacin, enoxacin, lomefloxacin, norfloxacin and ofloxacin. | Acta poloniae pharmaceutica 20041201 |
[Simultaneous determination of quinolones in foods by LC/MS/MS]. | Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20041001 |
Mycobacterium tuberculosis DNA gyrase: interaction with quinolones and correlation with antimycobacterial drug activity. | Antimicrobial agents and chemotherapy 20040401 |
Enoxacin trihydrate. | Acta crystallographica. Section C, Crystal structure communications 20040401 |
Partial least squares multicomponent fluorimetric determination of fluoroquinolones in human urine samples. | Talanta 20040310 |
Sensitivity and spectrum of bacterial isolates in infectious otitis externa. | Journal of the College of Physicians and Surgeons--Pakistan : JCPSP 20040301 |
Effects of eight antibacterial agents on cell survival and expression of epithelial-cell- or cell-adhesion-related genes in human gingival epithelial cells. | Journal of periodontal research 20040201 |
Comparative evaluation of antiproliferative activity and induction of apoptosis by some fluoroquinolones with a human non-small cell lung cancer cell line in culture. | Asian Pacific journal of cancer prevention : APJCP 20040101 |
Cotransport of macrolide and fluoroquinolones, a beneficial interaction reversing P-glycoprotein efflux. | American journal of therapeutics 20040101 |
Spectroscopic properties of various quinolone antibiotics in aqueous-organic solvent mixtures. | Photochemistry and photobiology 20040101 |
A randomized controlled trial (volunteer study) of sitafloxacin, enoxacin, levofloxacin and sparfloxacin phototoxicity. | The British journal of dermatology 20031201 |
Effects of anti-inflammatory drugs on convulsant activity of quinolones: a comparative study of drug interaction between quinolones and anti-inflammatory drugs. | Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20031201 |
Corneal and scleral permeability of quinolones--a pharmacokinetics study. | Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20031201 |
Flow-injection analysis of two fluoquinolones by the sensitizing effect of terbium(III) on chemiluminescence of the potassium permanganate-sodium sulfite system. | Talanta 20031104 |
Relationship between extent of inhibition and inhibitor dose: literature evaluation based on the metabolism and transport drug interaction database. | Current drug metabolism 20031001 |
Synthesis and in vitro antibacterial evaluation of N-[5-(5-nitro-2-thienyl)-1,3,4-thiadiazole-2-yl] piperazinyl quinolones. | European journal of medicinal chemistry 20030901 |
[Analysis of the response factors of different quinolones detected by evaporative light-scattering detector]. | Yao xue xue bao = Acta pharmaceutica Sinica 20030901 |
Binding characteristics of fluoroquinolones to synthetic levodopa melanin. | The Journal of pharmacy and pharmacology 20030801 |
[Surveillance on concurrent administration of quinolones and anti-inflammatory drugs in a community hospital]. | The Japanese journal of antibiotics 20030801 |
Interference-free analysis using three-way fluorescence data and the parallel factor model. Determination of fluoroquinolone antibiotics in human serum. | Analytical chemistry 20030601 |
[Synthesis and antibacterial activity of pyridonecarboxylic acid derivatives containing 2-methyl-5-nitroimidazol]. | Yao xue xue bao = Acta pharmaceutica Sinica 20030401 |
Direct determination of four fluoroquinolones, enoxacin, norfloxacin, ofloxacin, and ciprofloxacin, in pharmaceuticals and blood serum by HPLC. | Analytical and bioanalytical chemistry 20030301 |
Aetiology of shigellosis in northern Pakistan. | Journal of health, population, and nutrition 20030301 |
Pharmacological evaluation of garenoxacin, a novel des-F(6)-quinolone antimicrobial agent: effects on the central nervous system. | The Journal of toxicological sciences 20030201 |
Dead bugs don't mutate: susceptibility issues in the emergence of bacterial resistance. | Emerging infectious diseases 20030101 |
[The history of the development and changes of quinolone antibacterial agents]. | Yakushigaku zasshi 20030101 |
Photo-induced interaction of antibacterial quinolones with human serum albumin. | Toxicology mechanisms and methods 20030101 |
Identification and characterization of a novel efflux-related multidrug resistance phenotype in Staphylococcus aureus. | The Journal of antimicrobial chemotherapy 20021201 |
Laser flash photolysis study of photoionization in fluoroquinolones. | Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20021101 |
The expanding role of fluoroquinolones. | The American journal of medicine 20020708 |
Spectrophotometric determination of enoxacin as ion-pairs with bromophenol blue and bromocresol purple in bulk and pharmaceutical dosage form. | Journal of pharmaceutical and biomedical analysis 20020701 |
[Phototoxicity studies of pazufloxacin mesilate, a novel parenteral quinolone antimicrobial agent--in vitro and in vivo studies]. | The Japanese journal of antibiotics 20020601 |
[Drug interactions between nonsteroidal anti-inflammatory drug and pazufloxacin mesilate, a new quinolone antibacterial agent for intravenous use: convulsions in mice after intravenous or intracerebroventricular administration]. | The Japanese journal of antibiotics 20020601 |
In vitro photochemical clastogenicity of quinolone antibacterial agents studied by a chromosomal aberration test with light irradiation. | Mutation research 20020527 |
Osteoadsorptive bisphosphonate derivatives of fluoroquinolone antibacterials. | Journal of medicinal chemistry 20020523 |
Multiresidue determination of (fluoro)quinolone antibiotics in swine kidney using liquid chromatography-tandem mass spectrometry. | Journal of chromatography. A 20020405 |
Possible involvement of P-glycoprotein in the biliary excretion of grepafloxacin. | Clinical and experimental pharmacology & physiology 20020301 |
Possible gatifloxacin-induced fulminant hepatic failure. | The Annals of pharmacotherapy 20020101 |
Antituberculosis agents. III. In vitro evaluation of antimycobacterial activity and cytotoxicity of some N-piperazinyl quinolone derivatives. | Bollettino chimico farmaceutico 20020101 |
Quinolones and false-positive urine screening for opiates by immunoassay technology. | JAMA 20011226 |
In vitro method for prediction of the phototoxic potentials of fluoroquinolones. | Toxicology in vitro : an international journal published in association with BIBRA 20011201 |
A pharmacokinetic/pharmacodynamic approach to show that not all fluoroquinolones exhibit similar sensitivity toward the proconvulsant effect of biphenyl acetic acid in rats. | The Journal of antimicrobial chemotherapy 20011201 |
Biphenylacetic acid enhances the antagonistic action of fluoroquinolones on the GABA(A)-mediated responses of the isolated guinea-pig ileum. | Pharmacological research 20010901 |
Is more than one quinolone needed in clinical practice? | The Annals of pharmacotherapy 20010901 |
Inhibitory effect of quinolone antimicrobial and nonsteroidal anti-inflammatory drugs on a medium chain acyl-CoA synthetase. | Biochemical pharmacology 20010801 |
[Terbium sensitized chemiluminescence of enoxacin]. | Yao xue xue bao = Acta pharmaceutica Sinica 20010801 |
Polysaccharide synthesis as a carbon dissipation mechanism in metabolically uncoupled Xanthomonas campestris cells. | Journal of biotechnology 20010726 |
Effect of liposomes and niosomes on skin permeation of enoxacin. | International journal of pharmaceutics 20010521 |
[Convulsion following the combination of single preoperative oral administration of enoxacine and single postoperative intravenous administration of flurbiprofen axetil]. | Masui. The Japanese journal of anesthesiology 20010401 |
Analysis of fluoroquinolone-mediated photosensitization of 2'-deoxyguanosine, calf thymus and cellular DNA: determination of type-I, type-II and triplet-triplet energy transfer mechanism contribution. | Photochemistry and photobiology 20010301 |
[Effect of subinhibitory levels of aminoglycosides and fluoroquinolines on hydrophobicity and motility of Serratia marcescens]. | Epidemiologie, mikrobiologie, imunologie : casopis Spolecnosti pro epidemiologii a mikrobiologii Ceske lekarske spolecnosti J.E. Purkyne 20010201 |
Selective separation and simultaneous determination of trace levels of five types of fluorinated quinolone drugs by thin-layer chromatography/fluorescence densitometry. | Journal of AOAC International 20010101 |
History of quinolones and their side effects. | Chemotherapy 20010101 |
Comparison of side effects of levofloxacin versus other fluoroquinolones. | Chemotherapy 20010101 |
Evidence of different profiles of side effects and drug-drug interactions among the quinolones--the pharmacokinetic standpoint. | Chemotherapy 20010101 |
Pharmacokinetic aspects of treating infections in the intensive care unit: focus on drug interactions. | Clinical pharmacokinetics 20010101 |
Profiles of hepatic and dysrhythmic cardiovascular events following use of fluoroquinolone antibacterials: experience from large cohorts from the Drug Safety Research Unit Prescription-Event Monitoring database. | Drug safety 20010101 |
Synthesis and antibacterial activity of some novel N-substituted piperazinyl-quinolones. | Bollettino chimico farmaceutico 20010101 |
Pharmacokinetics of enoxacin and its oxometabolite after multiple oral dosing and penetration into prostatic tissue. | The Journal of antimicrobial chemotherapy 20001201 |
Prediction of quinolone activity against Mycobacterium avium by molecular topology and virtual computational screening. | Antimicrobial agents and chemotherapy 20001001 |
Anti-toxoplasma activities of 24 quinolones and fluoroquinolones in vitro: prediction of activity by molecular topology and virtual computational techniques. | Antimicrobial agents and chemotherapy 20001001 |
A new fluoroquinolone derivative exhibits inhibitory activity against human immunodeficiency virus type 1 replication. | Chemotherapy 19990101 |
Cross-reactivity in murine fluoroquinolone photoallergy: exclusive usage of TCR Vbeta13 by immune T cells that recognize fluoroquinolone-photomodified cells. | Journal of immunology (Baltimore, Md. : 1950) 19980415 |
Role of nitric oxide in the convulsions following the coadministration of enoxacin with fenbufen in mice. | Japanese journal of pharmacology 19980401 |
Neurotoxicodynamics of the interaction between ciprofloxacin and foscarnet in mice. | Antimicrobial agents and chemotherapy 19980301 |
Role of nitric oxide in the convulsive seizures induced by fluoroquinolones coadministered with 4-biphenyl acetic acid. | General pharmacology 19971101 |
Circadian variation in enoxacin-induced convulsions in mice coadministered with fenbufen. | Japanese journal of pharmacology 19970201 |
N-1-tert-butyl-substituted quinolones: in vitro anti-Mycobacterium avium activities and structure-activity relationship studies. | Antimicrobial agents and chemotherapy 19961101 |
Epileptogenic activity induced by combined treatment with antiinflammatory drugs and enoxacin and its inhibition by a calcium antagonist, nicardipine. | Methods and findings in experimental and clinical pharmacology 19961101 |
Structure-activity relationships of quinolone agents against mycobacteria: effect of structural modifications at the 8 position. | Antimicrobial agents and chemotherapy 19961001 |
Intermolecular interactions of antimicrobial fluoroquinolones with purified rat liver CYP1A2 studied by proton nuclear magnetic resonance spectroscopy. | Xenobiotica; the fate of foreign compounds in biological systems 19961001 |
[In vitro anti-MAC activities of new quinolones in focus (2)]. | Kekkaku : [Tuberculosis] 19960901 |
Interaction between enoxacin, a new antimicrobial, and nimesulide, a new non-steroidal anti-inflammatory agent in mice. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 19960801 |
Effects of some quinolones on imipenem-induced seizures in DBA/2 mice. | General pharmacology 19940301 |
In-vitro activities of quinolones against mycobacteria. | The Journal of antimicrobial chemotherapy 19931201 |
Acute cholestatic liver injury induced by enoxacin. | Journal of hepatology 19930401 |
[Effects of drugs on the convulsions induced by the combination of a new quinolone antimicrobial, enoxacin, and a nonsteroidal anti-inflammatory drug, fenbufen, in mice]. | Nihon yakurigaku zasshi. Folia pharmacologica Japonica 19921001 |
Repeated treatment with quinolones potentiates the seizures induced by aminophylline in genetically epilepsy-prone rats. | General pharmacology 19920901 |
Enoxacin acute liver injury. | Journal of hepatology 19920501 |
Interaction of the new quinolone antibacterial agent levofloxacin with fenbufen in mice. | Arzneimittel-Forschung 19920301 |
Assessment of temafloxacin neurotoxicity in rodents. | The American journal of medicine 19911230 |
Hippocampus and frontal cortex are the potential mediatory sites for convulsions induced by new quinolones and non-steroidal anti-inflammatory drugs. | International journal of clinical pharmacology, therapy, and toxicology 19910601 |
Responsiveness of genetically epilepsy-prone rats to aminophylline-induced seizures and interactions with quinolones. | Neuropharmacology 19910201 |
Fluoroquinolones protect the human lymphocyte CEM cell line from HIV-1-mediated cytotoxicity. | Cell structure and function 19901001 |
Comparative in-vitro activities of ten fluoroquinolones and fusidic acid against Mycobacterium spp. | The Journal of antimicrobial chemotherapy 19900901 |
In vitro and in vivo antibacterial activities of AT-4140, a new broad-spectrum quinolone. | Antimicrobial agents and chemotherapy 19890801 |
Comparative antimycobacterial activities of difloxacin, temafloxacin, enoxacin, pefloxacin, reference fluoroquinolones, and a new macrolide, clarithromycin. | Antimicrobial agents and chemotherapy 19890401 |
Effect of enoxacin on theophylline neurotoxicity. | Life sciences 19890101 |
Norfloxacin and seizures. | Annals of internal medicine 19880715 |
Enoxacin in acute exacerbations of chronic bronchitis: a comparison with amoxycillin. | The Journal of antimicrobial chemotherapy 19880201 |
Enoxacin in the treatment of lower respiratory tract infections. | The Journal of antimicrobial chemotherapy 19880201 |
Activity of five fluoroquinolones against Mycobacterium avium-intracellulare complex and M. xenopi. | Annales de l'Institut Pasteur. Microbiology 19880101 |
Comparative in-vitro activity of five fluoroquinolones against mycobacteria. | The Journal of antimicrobial chemotherapy 19870501 |
In-vitro activity of six fluorinated quinolones against Mycobacterium tuberculosis. | The Journal of antimicrobial chemotherapy 19870501 |
Activity of ciprofloxacin and other fluorinated quinolones against mycobacteria. | The American journal of medicine 19870427 |