Home Carboxys (S)-1-((S)-2-(((S)-1-Carboxy-3-phenylpropyl)amino)propanoyl)pyrrolidine-2-carboxylic acid

(S)-1-((S)-2-(((S)-1-Carboxy-3-phenylpropyl)amino)propanoyl)pyrrolidine-2-carboxylic acid

CAS No.:
76420-72-9
Catalog Number:
AG005BSZ
Molecular Formula:
C18H24N2O5
Molecular Weight:
348.3936
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5mg
98%(HPLC)
In Stock USA
United States
$116
- +
10mg
98%(HPLC)
In Stock USA
United States
$211
- +
50mg
98%(HPLC)
In Stock USA
United States
$586
- +
Product Description
Catalog Number:
AG005BSZ
Chemical Name:
(S)-1-((S)-2-(((S)-1-Carboxy-3-phenylpropyl)amino)propanoyl)pyrrolidine-2-carboxylic acid
CAS Number:
76420-72-9
Molecular Formula:
C18H24N2O5
Molecular Weight:
348.3936
MDL Number:
MFCD00865786
IUPAC Name:
(2S)-1-[(2S)-2-[[(1S)-1-carboxy-3-phenylpropyl]amino]propanoyl]pyrrolidine-2-carboxylic acid
InChI:
InChI=1S/C18H24N2O5/c1-12(16(21)20-11-5-8-15(20)18(24)25)19-14(17(22)23)10-9-13-6-3-2-4-7-13/h2-4,6-7,12,14-15,19H,5,8-11H2,1H3,(H,22,23)(H,24,25)/t12-,14-,15-/m0/s1
InChI Key:
LZFZMUMEGBBDTC-QEJZJMRPSA-N
SMILES:
OC(=O)[C@@H](N[C@H](C(=O)N1CCC[C@H]1C(=O)O)C)CCc1ccccc1
EC Number:
278-459-3
UNII:
Q508Q118JM
NSC Number:
760053
Properties
Complexity:
490  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
3  
Defined Bond Stereocenter Count:
0
Exact Mass:
348.169g/mol
Formal Charge:
0
Heavy Atom Count:
25  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
3  
Isotope Atom Count:
0
Molecular Weight:
348.399g/mol
Monoisotopic Mass:
348.169g/mol
Rotatable Bond Count:
8  
Topological Polar Surface Area:
107A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-0.7  
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On call. I reread your articles on congestive heart failure when I was diagnosed with the condition last month. My breathing is back to normal, and I feel well. My doctor has prescribed all the medications you recommended, but he disagreed with one. He said that since I'm taking Vasotec, I should stop my aspirin. Do you agree? Harvard men's health watch 20060201
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Domain-selective ligand-binding modes and atomic level pharmacophore refinement in angiotensin I converting enzyme (ACE) inhibitors. Chembiochem : a European journal of chemical biology 20050601
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Role of PGI2 and effects of ACE inhibition on the bradykinin potentiation by angiotensin-(1-7) in resistance vessels of SHR. Regulatory peptides 20050415
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High-performance liquid chromatographic determination of enalapril in human plasma by enzyme kinetic analytical method. Journal of pharmaceutical and biomedical analysis 20050401
Different effects of imidapril and enalapril on aminopeptidase P activity in the mouse trachea. Hypertension research : official journal of the Japanese Society of Hypertension 20050301
Superoxide scavenging attenuates renal responses to ANG II during nitric oxide synthase inhibition in anesthetized dogs. American journal of physiology. Renal physiology 20050201
The role of angiotensin converting enzyme 2 in the generation of angiotensin 1-7 by rat proximal tubules. American journal of physiology. Renal physiology 20050201
Kinin peptides in human trapezius muscle during sustained isometric contraction and their relation to pain. Journal of applied physiology (Bethesda, Md. : 1985) 20050201
Partial angiotensin-converting enzyme inhibition during acute orthostatic stress in persons with tetraplegia. The journal of spinal cord medicine 20050101
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Simultaneous determination of enalapril and enalaprilat in human plasma by liquid chromatography-tandem mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20041225
Effects of enalaprilat infusion on hemodynamics and renal function in patients undergoing cardiac surgery. Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology 20041201
Pharmacokinetics and pharmacokinetic/pharmacodynamic relationships for angiotensin-converting enzyme inhibitors. Journal of veterinary pharmacology and therapeutics 20041201
Kinin B1 receptors stimulate nitric oxide production in endothelial cells: signaling pathways activated by angiotensin I-converting enzyme inhibitors and peptide ligands. Molecular pharmacology 20041101
Brain angiotensin-converting enzyme activity and autonomic regulation in heart failure. American journal of physiology. Heart and circulatory physiology 20041101
Oxidant stress in kidneys of spontaneously hypertensive rats involves both oxidase overexpression and loss of extracellular superoxide dismutase. American journal of physiology. Renal physiology 20041101
Lisinopril quantification in human plasma by liquid chromatography-electrospray tandem mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20041005
Predominant postglomerular vascular resistance response to reflex renal sympathetic nerve activation during ANG II clamp in rabbits. American journal of physiology. Regulatory, integrative and comparative physiology 20041001
A calorimetric study of the binding of lisinopril, enalaprilat and captopril to angiotensin-converting enzyme. Biophysical chemistry 20041001
Androgens augment proximal tubule transport. American journal of physiology. Renal physiology 20040901
Intracellular and extracellular angiotensin II enhance the L-type calcium current in the failing heart. Hypertension (Dallas, Tex. : 1979) 20040901
Ouabain at nanomolar concentration promotes synthesis and release of angiotensin II from the endothelium of the tail vascular bed of spontaneously hypertensive rats. Journal of cardiovascular pharmacology 20040901
In vitro effects of antihypertensive drugs on thromboxane agonist (U46619)-induced vasoconstriction in human internal mammary artery. British journal of anaesthesia 20040801
Structural details on the binding of antihypertensive drugs captopril and enalaprilat to human testicular angiotensin I-converting enzyme. Biochemistry 20040713
Role of brain and peripheral angiotensin II in hypertension and altered arterial baroreflex programmed during fetal life in rat. Pediatric research 20040601
Gender differences in angiotensin-converting enzyme (ACE) activity and inhibition by enalaprilat in healthy volunteers. Journal of cardiovascular pharmacology 20040501
Pharmacological therapy for myocardial reperfusion injury. Current opinion in pharmacology 20040401
Losartan but not enalaprilat acutely reduces reperfusion ventricular tachyarrhythmias in hypertrophied rat hearts after low-flow ischaemia. The Journal of pharmacy and pharmacology 20040401
[Intravenous enalapril does not prevent tachycardia-induced acute atrial electrical remodeling]. Revista espanola de cardiologia 20040401
Cardioprotective effect of zofenopril in perfused rat heart subjected to ischemia and reperfusion. Journal of cardiovascular pharmacology 20040201
Experimental design optimization of a capillary zone electrophoresis method for the screening of several diuretics and ACE inhibitors. Journal of chromatographic science 20040201
Oxidant stress leads to impaired regulation of renal cortical oxygen consumption by nitric oxide in the aging kidney. Journal of the American Society of Nephrology : JASN 20040101
Determination of the cis-trans isomerization barrier of enalaprilat by dynamic capillary electrophoresis and computer simulation. Electrophoresis 20040101
Characterization of the pharmacokinetic and pharmacodynamic properties of the angiotensin-converting enzyme inhibitor, enalapril, in horses. Journal of veterinary internal medicine 20040101
Increased renovascular response to angiotensin II in persons genetically predisposed to arterial hypertension disappears after chronic angiotensin-converting enzyme inhibition. Journal of hypertension 20040101
Evaluation of the bioequivalence of two tablet formulations of enalapril/hydrochlorothiazide after single oral administration to healthy volunteers. Arzneimittel-Forschung 20040101
Hyponatremic hypertensive syndrome (HHS) in an 18-month old-child presenting as malignant hypertension: a case report. BMC nephrology 20040101
Evaluation of the efficacy, safety and tolerability of intravenous enalaprilat in the treatment of grade III essential hypertension in Indian patients. Indian heart journal 20040101
In vitro pharmacological inhibition of human vascular smooth muscle cell proliferation for the prevention of hemodialysis vascular access stenosis. Blood purification 20040101
Endogenous angiotensin II in the regulation of hypoxic pulmonary vasoconstriction in anaesthetized dogs. Critical care (London, England) 20040101
Pharmacological and clinical studies with temocapril, an angiotensin converting enzyme inhibitor that is excreted in the bile. Cardiovascular drug reviews 20040101
Angiotensin converting anzyme (ACE) activity in porcine ocular tissue: effects of diet and ACE inhibitors. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20031201
Effect of angiotensin II type 2 receptor blockade on activation of mitogen-activated protein kinases after ischemia-reperfusion in isolated working rat hearts. Journal of cardiovascular pharmacology and therapeutics 20031201
Omapatrilat increases renal endothelin in deoxycorticosterone acetate-salt hypertensive rats. Vascular pharmacology 20031201
Effects of different angiotensins during acute, double blockade of the renin system in conscious dogs. American journal of physiology. Regulatory, integrative and comparative physiology 20031101
A novel activation process of protein kinase C in the remote, non-ischemic area of an infarcted heart is mediated by angiotensin-AT1 receptors. Journal of molecular and cellular cardiology 20031101
Angiotensin-(1-7) formation in the intact human heart: in vivo dependence on angiotensin II as substrate. Circulation 20031007
Bioequivalence evaluation of two brands of enalapril 20 mg tablets (Narapril and Renitec) in healthy human volunteers. Biopharmaceutics & drug disposition 20031001
Relative bioavailability study of 20-mg enalapril tablets in healthy male volunteers. Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20031001
NAD(P)H oxidase-generated superoxide anion accounts for reduced control of myocardial O2 consumption by NO in old Fischer 344 rats. American journal of physiology. Heart and circulatory physiology 20030901
Evaluation of the hypertensive infant: a rational approach to diagnosis. Radiologic clinics of North America 20030901
Further studies on the effect of intracellular angiotensins on heart cell communication: on the role of endogenous angiotensin II. Regulatory peptides 20030815
Differentiation between acute cyclosporine nephrotoxicity and acute tubular necrosis using enalaprilat renal scintigraphy in rats. Investigative radiology 20030801
Do angiotensin-converting enzyme inhibitors directly stimulate the kinin B1 receptor? American journal of physiology. Heart and circulatory physiology 20030701
Regional norepinephrine spillover in response to angiotensin-converting enzyme inhibition in healthy subjects. Journal of hypertension 20030701
Effects of enalaprilat on venoconstriction to norepinephrine: role of prostaglandins. Cardiovascular research 20030701
Effect of enalaprilat on postoperative hypertension after surgical repair of coarctation of the aorta. Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 20030701
Bradykinin metabolism in rat hearts with left-ventricular hypertrophy following myocardial infarction. Canadian journal of physiology and pharmacology 20030701
Angiotensin II-induced modulation of endothelium-dependent relaxation in rabbit mesenteric resistance arteries. The Journal of physiology 20030501
Enalaprilat, losartan and LU 135252 in coronary blood flow regulation. European journal of clinical investigation 20030501
Protective effects of quinaprilat and trandolaprilat, active metabolites of quinapril and trandolapril, on hemolysis induced by lysophosphatidylcholine in human erythrocytes. Biological & pharmaceutical bulletin 20030501
Enalapril does not alter adhesion molecule levels in human endotoxemia. Shock (Augusta, Ga.) 20030501
Beneficial hemodynamic and renal effects of intravenous enalaprilat following coronary artery bypass surgery complicated by left ventricular dysfunction. Critical care medicine 20030501
Is there an 'ACE' in the hole for postcoronary artery bypass graft myocardial dysfunction? Critical care medicine 20030501
Bioequivalence study of two brands of enalapril tablets after single oral administration to healthy volunteers. International journal of clinical pharmacology and therapeutics 20030501
RP-HPLC and NMR study of cis-trans isomerization of enalaprilat. Journal of pharmaceutical and biomedical analysis 20030326
Myocardial uptake and biochemical and hemodynamic effects of ACE inhibitors in humans. Hypertension (Dallas, Tex. : 1979) 20030301
Role of angiotensin II in the neural control of renal function. Hypertension (Dallas, Tex. : 1979) 20030301
Enalaprilat improves systemic and mesenteric blood flow during resuscitation from hemorrhagic shock in dogs. Shock (Augusta, Ga.) 20030301
Angiotensin-converting enzyme inhibition increases human vascular tissue-type plasminogen activator release through endogenous bradykinin. Circulation 20030204
The novel serine protease PreR-Co promotes endothelium-independent vasorelaxation in rabbit aortic rings. American journal of physiology. Heart and circulatory physiology 20030201
Blood pressure response to conventional and low-dose enalapril in chronic renal failure. British journal of clinical pharmacology 20030201
Current medical treatment for the exacerbation of chronic heart failure resulting in hospitalization. American heart journal 20030201
The bradykinin BK2 receptor mediates angiotensin II receptor type 2 stimulated rat duodenal mucosal alkaline secretion. BMC physiology 20030101
Simultaneous quantitation of enalapril and enalaprilat in human plasma by 96-well solid-phase extraction and liquid chromatography/tandem mass spectrometry. Rapid communications in mass spectrometry : RCM 20030101
Angiotensin II blockade augments renal cortical microvascular pO2 indicating a novel, potentially renoprotective action. Nephron. Physiology 20030101
Drug absorption from the isolated perfused rat lung--correlations with drug physicochemical properties and epithelial permeability. Journal of drug targeting 20030101
Effects of an angiotensin II receptor antagonist and angiotensin-converting enzyme inhibitors on burst forming units-erythroid in chronic hemodialysis patients. American journal of nephrology 20030101
Clinical review: the management of hypertensive crises. Critical care (London, England) 20030101
Captopril and enalaprilat decrease antioxidant defences in human endothelial cells and are unable to protect against apoptosis. Cell biology international 20030101
Angiotensin-converting enzyme inhibition modulates high-glucose-induced extracellular matrix changes in mouse glomerular epithelial cells. Nephron. Experimental nephrology 20030101
Hypertensive emergencies. Etiology and management. American journal of cardiovascular drugs : drugs, devices, and other interventions 20030101
ACE Inhibition with moexipril: a review of potential effects beyond blood pressure control. American journal of cardiovascular drugs : drugs, devices, and other interventions 20030101
Prejunctional AT(1) receptor subtype-dependent modification of neurotransmitter releases in canine isolated splenic arteries. Autonomic & autacoid pharmacology 20030101
2002 Alfred Burger Award Address in Medicinal Chemistry. Natural products and design: interrelated approaches in drug discovery. Journal of medicinal chemistry 20021219
Hemodynamics of early tubuloglomerular feedback resetting during reduced proximal reabsorption. Kidney international 20021201
Management of patients with hypertensive urgencies and emergencies: a systematic review of the literature. Journal of general internal medicine 20021201
Activation of bradykinin B1 receptor by ACE inhibitors. International immunopharmacology 20021201
Activation of a renin-angiotensin system in ischemic cardiac sympathetic nerve endings and its association with norepinephrine release. International immunopharmacology 20021201
Influence of propranolol, enalaprilat, verapamil, and caffeine on adenosine A(2A)-receptor-mediated coronary vasodilation. Journal of the American College of Cardiology 20021106
Angiotensin II contributes to arterial compliance in congestive heart failure. American journal of physiology. Heart and circulatory physiology 20021001
Zofenopril inhibits the expression of adhesion molecules on endothelial cells by reducing reactive oxygen species. American journal of hypertension 20021001
Haemodynamic effects of an angiotensin-converting enzyme inhibitor and angiotensin receptor antagonist during hypovolaemia in the anaesthetized pig. British journal of anaesthesia 20021001
Captopril and quinapril reduce reactive oxygen species. European journal of clinical investigation 20021001
Renal interstitial fluid angiotensin I and angiotensin II concentrations during local angiotensin-converting enzyme inhibition. Journal of the American Society of Nephrology : JASN 20020901
Angiotensin inhibition and coronary autoregulation in a canine model of LV hypertrophy. Basic research in cardiology 20020901
Ischemia promotes renin activation and angiotensin formation in sympathetic nerve terminals isolated from the human heart: contribution to carrier-mediated norepinephrine release. The Journal of pharmacology and experimental therapeutics 20020801
Impaired regulation of renal oxygen consumption in spontaneously hypertensive rats. Journal of the American Society of Nephrology : JASN 20020701
Icatibant blocks but does not reverse ACE inhibitor renal effect in Goldblatt rabbit. Clinical and experimental hypertension (New York, N.Y. : 1993) 20020701
Angiotensin-converting enzyme inhibitors improve coronary flow reserve in dilated cardiomyopathy by a bradykinin-mediated, nitric oxide-dependent mechanism. Circulation 20020611
Investigation of polymeric nanoparticles as carriers of enalaprilat for oral administration. International journal of pharmaceutics 20020604
Renal nerve stimulation augments effect of intraluminal angiotensin II on proximal tubule transport. American journal of physiology. Renal physiology 20020601
Biochemical basis of angioedema associated with recombinant tissue plasminogen activator treatment: an in vitro experimental approach. Stroke 20020601
Determination of enalapril and enalaprilat by enzyme linked immunosorbent assays: application to pharmacokinetic and pharmacodynamic analysis. Fundamental & clinical pharmacology 20020601
Bioequivalence study of enalapril tablets in healthy Thai male volunteers. Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20020601
Novel mode of action of angiotensin I converting enzyme inhibitors: direct activation of bradykinin B1 receptor. The Journal of biological chemistry 20020510
Endogenous endothelium-derived nitric oxide inhibits myocardial caspase activity: implications for treatment of end-stage heart failure. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20020501
AT(1) and AT(2) receptor expression and blockade after acute ischemia-reperfusion in isolated working rat hearts. American journal of physiology. Heart and circulatory physiology 20020401
Optimisation and validation of an angiotensin-converting enzyme inhibition assay for the screening of bioactive peptides. Journal of biochemical and biophysical methods 20020304
Endothelial function studies in pulmonary vascular disease: determination of angiotensin converting enzyme activity in humans (review). International journal of molecular medicine 20020301
Enalaprilat improves systemic cardiovascular parameters and mesenteric blood flow during hypotensive resuscitation from hemorrhagic shock in dogs. Shock (Augusta, Ga.) 20020301
Angiotensin I-converting enzyme inhibition increases cardiac catecholamine content and reduces monoamine oxidase activity via an angiotensin type 1 receptor-mediated mechanism. The Journal of pharmacology and experimental therapeutics 20020201
Intracellular angiotensin II stimulates voltage-operated Ca(2+) channels in arterial myocytes. Hypertension (Dallas, Tex. : 1979) 20020201
Studies on the angiotensin-converting enzyme and the kinin B2 receptor in the rabbit jugular vein: modulation of contractile response to bradykinin. Canadian journal of physiology and pharmacology 20020201
Renal interstitial fluid concentrations of angiotensins I and II in anesthetized rats. Hypertension (Dallas, Tex. : 1979) 20020101
Pharmacokinetic and pharmacodynamic comparative study of zofenopril and enalapril in healthy volunteers. Arzneimittel-Forschung 20020101
Comparative bioavailability of two immediate release tablets of enalapril/hydrochlorothiazide in healthy volunteers. European journal of drug metabolism and pharmacokinetics 20020101
Protection of the cardiovascular system by imidapril, a versatile angiotensin-converting enzyme inhibitor. Cardiovascular drug reviews 20020101
Effect of angiotensin-converting enzyme inhibitors on liver regeneration in rats. Hepato-gastroenterology 20020101
[The use of enalaprilat for the treatment of uncomplicated hypertensive crises in patients with hypertensive disease (essential hypertension)]. Kardiologiia 20020101
Transporter-mediated Drug Interactions. Drug metabolism and pharmacokinetics 20020101
Effects of intracoronary low-dose enalaprilat as an adjunct to primary percutaneous transluminal coronary angiography in acute myocardial infarction. The American journal of cardiology 20011215
High serum enalaprilat in chronic renal failure. Journal of the renin-angiotensin-aldosterone system : JRAAS 20011201
Enalaprilat blunts reflexive increases in cardiac interstitial norepinephrine in conscious rats. Journal of hypertension 20011101
The pharmacokinetics of enalapril in children and infants with hypertension. Journal of clinical pharmacology 20011001
Attenuation of angiotensin II-mediated coronary vasoconstriction and vasodilatory action of angiotensin-converting enzyme inhibitor in pacing-induced heart failure in dogs. Journal of the American College of Cardiology 20011001
Inhibition of serum angiotensin-converting enzyme in rabbits after intravenous administration of enalaprilat-loaded intact erythrocytes. The Journal of pharmacy and pharmacology 20010901
Pathophysiological roles of endogenous endothelin-1 in dogs with chronic heart failure produced by rapid right ventricular pacing. The Journal of pharmacology and experimental therapeutics 20010801
Cardiac nitric oxide production due to angiotensin-converting enzyme inhibition decreases beta-adrenergic myocardial contractility in patients with dilated cardiomyopathy. Journal of the American College of Cardiology 20010801
High tissue affinity angiotensin-converting enzyme inhibitors improve endothelial function and reduce infarct size. The Annals of thoracic surgery 20010801
[In contrast to captopril and enalapril, losartan does not increase mortality of gerbils after carotid ligation]. Archives des maladies du coeur et des vaisseaux 20010801
Effects of enalaprilat on cardiorespiratory, hemodynamic, and hematologic variables in exercising horses. American journal of veterinary research 20010701
Metabolism of angiotensin I by guinea pig aqueous humor. Canadian journal of physiology and pharmacology 20010701
Effect of column temperature on the behaviour of some angiotensin converting enzyme inhibitors during high-performance liquid chromatographic analysis. Journal of chromatography. B, Biomedical sciences and applications 20010505
The canine Purkinje fiber: an in vitro model system for acquired long QT syndrome and drug-induced arrhythmogenesis. Journal of cardiovascular pharmacology 20010501
The bladder angiotensin system in female rats: response to infusions of angiotensin I and the angiotensin converting enzyme inhibitor enalaprilat. The Journal of urology 20010501
Influence of Ca(2+)-activated K(+) channels on rat renal arteriolar responses to depolarizing agonists. American journal of physiology. Renal physiology 20010401
Comparison of a vasopeptidase inhibitor with neutral endopeptidase and angiotensin-converting enzyme inhibitors on bradykinin metabolism in the rat coronary bed. Journal of cardiovascular pharmacology 20010401
Angiotensin converting enzyme (ACE) and non-ACE dependent angiotensin II generation in resistance arteries from patients with heart failure and coronary heart disease. Journal of the American College of Cardiology 20010315
The renal nerve is required for regulation of proximal tubule transport by intraluminally produced ANG II. American journal of physiology. Renal physiology 20010301
Determination of enzyme (angiotensin convertase) inhibitors based on enzymatic reaction followed by HPLC. Journal of pharmaceutical and biomedical analysis 20010301
The pancreatic islets in spontaneously hypertensive rats: islet blood flow and insulin production. European journal of endocrinology 20010201
Sevelamer hydrochloride (Renagel), a phosphate-binding polymer, does not alter the pharmacokinetics of two commonly used antihypertensives in healthy volunteers. Journal of clinical pharmacology 20010201
Tyrosine kinase involvement in renal arteriolar constrictor responses to angiotensin II. Hypertension (Dallas, Tex. : 1979) 20010201
A simple HPLC method for quantitation of enalaprilat. Journal of pharmaceutical and biomedical analysis 20010201
Haemodynamic and renal effects of intravenous enalaprilat during coronary artery bypass graft surgery in patients with ischaemic heart dysfunction. British journal of anaesthesia 20010201
Treatment of chronic hypertension with intravenous enalaprilat and transdermal clonidine. Pediatric nephrology (Berlin, Germany) 20010101
Effects of digoxin, furosemide, enalaprilat and metoprolol on endothelial function in young normotensive subjects. Clinical and experimental pharmacology & physiology 20010101
Enalaprilat attenuates ischemic rises in intracellular sodium in the isolated rat heart via the bradykinin receptor. Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 20010101
Comparative study of effects of angiotensin II receptor antagonist, KD3-671, and angiotensin converting enzyme inhibitor, enalaprilat, on cough reflex in guinea pig. European journal of drug metabolism and pharmacokinetics 20010101
In vitro characterization of human intact erythrocytes loaded by enalaprilat. Drug delivery 20010101
Effects of indomethacin on hemodynamic parameters after intravenous administration of propranolol and enalaprilat in rabbits. Polish journal of pharmacology 20010101
A comparative study between a calcium channel blocker (Nicardipine) and a combined alpha-beta-blocker (Labetalol) for the control of emergence hypertension during craniotomy for tumor surgery. Anesthesia and analgesia 20001001
Protective effect of imidaprilat, an angiotensin-converting enzyme inhibitor on *OH generation in rat myocardium. Biochimica et biophysica acta 19991018
Effects of renin-angiotensin blockade on sympathetic reactivity and beta-adrenergic pathway in the spontaneously hypertensive rat. Hypertension (Dallas, Tex. : 1979) 19970801
[Enalaprilat in the prevention of left ventricular hypertrophy induced by isoproterenol]. Arquivos brasileiros de cardiologia 19970701
[Effect of enalaprilat on cardiotoxicity induced by doxorubicin]. Arquivos brasileiros de cardiologia 19961001
Local action of the renin angiotensin system in the porcine ophthalmic circulation: effects of ACE-inhibitors and angiotensin receptor antagonists. Investigative ophthalmology & visual science 19950301
Endogenous vasopressin and renin-angiotensin systems support blood pressure after epidural block in humans. Anesthesiology 19940501
Replacement of L-Lys by D-Lys(NH2) in peptide Ala-Arg-Pro-Ala-Lys (peptide 6A) increases its coronary blood flow-promoting properties. Journal of cardiovascular pharmacology 19940101
Compared properties of trandolapril, enalapril, and their diacid metabolites. Journal of cardiovascular pharmacology 19940101
No relation of the suppressive effect on the sympathetic nervous system to the acute hypotension caused by imidapril and enalapril. Japanese journal of pharmacology 19931101
Influence of converting enzyme inhibition on isoflurane-induced hypotension for cerebral aneurysm surgery. Anaesthesia 19920301
Molecular and crystal structures of MDL27,467A hydrochloride and quinapril hydrochloride, two ester derivatives of potent angiotensin converting enzyme inhibitors. Journal of medicinal chemistry 19910201
Microvascular effects of cocaine; interaction with nitrendipine and enalaprilat. Journal of toxicology. Clinical toxicology 19910101
Angiotensin converting enzyme inhibitors: spirapril and related compounds. Journal of medicinal chemistry 19890701
Angiotensin-converting enzyme inhibitors. Mercaptan, carboxyalkyl dipeptide, and phosphinic acid inhibitors incorporating 4-substituted prolines. Journal of medicinal chemistry 19880601
The acute haemodynamic effects of intravenous enalaprilic acid (MK422) in patients with left ventricular dysfunction. British journal of clinical pharmacology 19870101
Enalapril and the kidney: renal vasodilation and natriuresis due to the inhibition of angiotensin II formation. Journal of cardiovascular pharmacology 19860101
Angiotensin-converting enzyme inhibitors potentiate the analgesic activity of [Met]-enkephalin-Arg6-Phe7 by inhibiting its degradation in mouse brain. Molecular pharmacology 19851201
Proteolytic conversion of [Met]enkephalin-Arg6-Gly7-Leu8 by brain synaptic membranes. Characterization of formed peptides and mechanism of proteolysis. The Journal of biological chemistry 19850310
An overview of the clinical pharmacology of enalapril. British journal of clinical pharmacology 19840101
Enalapril maleate (MK-421), a potent, nonsulfhydryl angiotensin-converting enzyme inhibitor: absorption, disposition, and metabolism in man. Drug metabolism reviews 19830101
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