Home Sulfos 4,4'-Diaminodiphenyl sulfone

4,4'-Diaminodiphenyl sulfone

CAS No.:
80-08-0
Catalog Number:
AG00558H
Molecular Formula:
C12H12N2O2S
Molecular Weight:
248.3009
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5g
99%(HPLC)
In Stock USA
United States
$39
- +
25g
99%(HPLC)
In Stock USA
United States
$48
- +
100g
99%(HPLC)
In Stock USA
United States
$80
- +
500g
99%(HPLC)
In Stock USA
United States
$201
- +
Product Description
Catalog Number:
AG00558H
Chemical Name:
4,4'-Diaminodiphenyl sulfone
CAS Number:
80-08-0
Molecular Formula:
C12H12N2O2S
Molecular Weight:
248.3009
MDL Number:
MFCD00007887
IUPAC Name:
4-(4-aminophenyl)sulfonylaniline
InChI:
InChI=1S/C12H12N2O2S/c13-9-1-5-11(6-2-9)17(15,16)12-7-3-10(14)4-8-12/h1-8H,13-14H2
InChI Key:
MQJKPEGWNLWLTK-UHFFFAOYSA-N
SMILES:
Nc1ccc(cc1)S(=O)(=O)c1ccc(cc1)N
EC Number:
201-248-4
UNII:
8W5C518302
Properties
Complexity:
306  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
248.062g/mol
Formal Charge:
0
Heavy Atom Count:
17  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
248.3g/mol
Monoisotopic Mass:
248.062g/mol
Rotatable Bond Count:
2  
Topological Polar Surface Area:
94.6A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
1  
Literature
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Agranulocytosis induced by multidrug therapy in leprosy treatment: a case report. The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases 20090401
Effect of conversion on the structure-property relationships of amine-cured epoxy thermosets. ACS applied materials & interfaces 20090401
Lest we forget Hansen's disease (leprosy): an unusual presentation with an acute onset of inflammatory polyarthritis and the rheumatology experience. International journal of rheumatic diseases 20090401
Synthesis and characterization of new optically active poly(azo-ester-imide)s via interfacial polycondensation. Amino acids 20090301
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[Treatment of chronic immune thrombocytopenic purpura. Looking for something better. Review]. Investigacion clinica 20090301
Leprosy: not always an easy diagnosis and often a management challenge. The Australasian journal of dermatology 20090201
Short report: comparison of chlorproguanil-dapsone with a combination of sulfadoxine-pyrimethamine and chloroquine in children with malaria in northcentral Nigeria. The American journal of tropical medicine and hygiene 20090201
Cutaneous granulomatous reaction from mesotherapy. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20090201
[Trends in therapy for Hansen disease]. Nihon Hansenbyo Gakkai zasshi = Japanese journal of leprosy : official organ of the Japanese Leprosy Association 20090201
Epidermolysis bullosa acquisita in an 18-year-old African-American male: a case report. South Dakota medicine : the journal of the South Dakota State Medical Association 20090201
Hansen's disease in Portugal: multibacillary patients treated between 1988 and 2003. Journal of the European Academy of Dermatology and Venereology : JEADV 20090101
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Question: Can you identify this condition? Tuberculoid leprosy. Canadian family physician Medecin de famille canadien 20090101
Childhood linear IgA bullous dermatosis in Tunisia. Pediatric dermatology 20090101
A case of juvenile bullous pemphigoid--successful treatment with diaminodiphenylsulfone and prednisone. Pediatric dermatology 20090101
Randomized trial of artesunate+amodiaquine, sulfadoxine-pyrimethamine+amodiaquine, chlorproguanal-dapsone and SP for malaria in pregnancy in Tanzania. PloS one 20090101
Bullous pemphigoid in a renal transplant recipient: a case report and review of the literature. American journal of clinical dermatology 20090101
Pyoderma gangrenosum associated with Sjögren syndrome. European journal of dermatology : EJD 20090101
Dapsone 5% gel: a review of its efficacy and safety in the treatment of acne vulgaris. American journal of clinical dermatology 20090101
Drug-to-drug interaction between dapsone and minocycline: an unusual cause of relapse of toxoplasmic encephalitis in an HIV-infected patient. Scandinavian journal of infectious diseases 20090101
Sweet syndrome associated with celiac disease. American journal of clinical dermatology 20090101
Chlorproguanil-dapsone-artesunate versus artemether-lumefantrine: a randomized, double-blind phase III trial in African children and adolescents with uncomplicated Plasmodium falciparum malaria. PloS one 20090101
Measurement of adherence, drug concentrations and the effectiveness of artemether-lumefantrine, chlorproguanil-dapsone or sulphadoxine-pyrimethamine in the treatment of uncomplicated malaria in Malawi. Malaria journal 20090101
Dapsone hypersensitivity syndrome in non-leprosy patients: a retrospective study of its incidence in a tertiary referral center in Taiwan. The Journal of dermatological treatment 20090101
Drug usage evaluation of dapsone. Indian journal of pharmaceutical sciences 20090101
Synthesis and characterization of aromatic-aliphatic polyamide nanocomposite films incorporating a thermally stable organoclay. Nanoscale research letters 20090101
Sensitive spectrophotometric methods for the assessment of nitrite in water sample. Environmental monitoring and assessment 20081201
Hematologic safety of dapsone gel, 5%, for topical treatment of acne vulgaris. Archives of dermatology 20081201
Granuloma annulare. Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia 20081201
Can leprosy be eradicated with chemotherapy? An evaluation of the Malta Leprosy Eradication Project. Leprosy review 20081201
A retrospective study of the effect of modified multi-drug therapy in Nepali leprosy patients following the development of adverse effects due to dapsone. Leprosy review 20081201
Dapsone-induced haemolytic anaemia, hepatitis and agranulocytosis in a leprosy patient with normal glucose-6-phosphate-dehydrogenase activity. Leprosy review 20081201
Antioxidant, antiinflammatory and antiapoptotic effects of dapsone in a model of brain ischemia/reperfusion in rats. Journal of neuroscience research 20081115
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry 20081113
A possible inhibitory action of diaminodiphenyl sulfone on tumour necrosis factor-alpha production from activated mononuclear cells on cutaneous lupus erythematosus. Clinical and experimental dermatology 20081101
[Sensory-motor neuropathy: a slow and misleading case of leprosy]. Revue neurologique 20081101
The effect of ethyl pyruvate on dapsone-induced methemoglobinemia in rats. Clinical toxicology (Philadelphia, Pa.) 20081101
Dapsone-induced hemolytic anemia in lung allograft recipients. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20081101
Sweet-like dermatosis in 2 patients with clinical features of dermatomyositis and underlying autoimmune disease. Archives of dermatology 20081101
Dapsone, danazol, and intrapartum splenectomy in refractory ITP complicating pregnancy. Indian journal of medical sciences 20081101
Dapsone-induced photosensitivity: a rare clinical presentation. Photodermatology, photoimmunology & photomedicine 20081001
The processing of English regular inflections: Phonological cues to morphological structure. Cognition 20081001
Type I reaction in a borderline leprosy case successfully treated with multidrug therapy and ofloxacin. International journal of dermatology 20081001
Specificity of the Toxoplasma gondii-altered behaviour to definitive versus non-definitive host predation risk. Parasitology 20080901
Tuberculoid leprosy and Type 1 lepra reaction. Travel medicine and infectious disease 20080901
Ocular cicatricial pemphigoid. Ophthalmology 20080901
Pyoderma gangrenosum following isotretinoin therapy for acne nodulocystic. International journal of dermatology 20080901
Pyoderma gangrenosum. The Journal of the Association of Physicians of India 20080901
Actinomycetoma by Nocardia brasiliensis in a girl with Down syndrome. Dermatology online journal 20080815
Primary cutaneous actinomycosis on the chest wall. Dermatology online journal 20080815
Dapsone induces oxidative stress and impairs antioxidant defenses in rat liver. Life sciences 20080801
HIV-seropositive patient with Sweet's syndrome and nodular scleritis, showing dramatic response after adding dapsone to systemic corticosteroid therapy. International journal of dermatology 20080801
Pruritic rash on the buttocks after a beach vacation: a case report. Cutis 20080801
Successful treatment of Melkersson-Rosenthal syndrome with dapsone and triamcinolone injections. Journal of the European Academy of Dermatology and Venereology : JEADV 20080801
Substrate proton to heme distances in CYP2C9 allelic variants and alterations by the heterotropic activator, dapsone. Archives of biochemistry and biophysics 20080715
Three indigenous cases of leprosy in the Mississippi delta. Southern medical journal 20080601
Might dermatitis herpetiformis be associated with discoid lupus erythematosus? Journal of the European Academy of Dermatology and Venereology : JEADV 20080601
Picture of the month. Chronic bullous dermatosis of childhood. Archives of pediatrics & adolescent medicine 20080601
Do safe and effective treatment options exist for patients with active pemphigus vulgaris who plan conception and pregnancy? Archives of dermatology 20080601
Evaluation of protective effects of Chi-Zhi-Huang decoction on Phase I drug metabolism of liver injured rats by cocktail probe drugs. Journal of ethnopharmacology 20080522
A novel assay system for myeloperoxidase activity in whole saliva. Clinical biochemistry 20080501
A randomised trial to assess the efficacy and safety of chlorproguanil/dapsone + artesunate for the treatment of uncomplicated Plasmodium falciparum malaria. Transactions of the Royal Society of Tropical Medicine and Hygiene 20080501
International open trial of uniform multi-drug therapy regimen for 6 months for all types of leprosy patients: rationale, design and preliminary results. Tropical medicine & international health : TM & IH 20080501
Subcorneal pustular dermatosis: 50 years on. Clinical and experimental dermatology 20080501
The therapeutic and prophylactic role of oral zinc sulfate in management of recurrent aphthous stomatitis (ras) in comparison with dapsone. Saudi medical journal 20080501
Prospective randomized non-blinded clinical trial on the use of dapsone plus antihistamine vs. antihistamine in patients with chronic idiopathic urticaria. Journal of the European Academy of Dermatology and Venereology : JEADV 20080401
Refractory idiopathic thrombocytopenic purpura treated with the soluble tumor necrosis factor receptor etanercept. American journal of hematology 20080401
Didactic lessons from the serum lactate dehydrogenase posttransplant: a clinical vignette. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20080401
Amicrobial pustular dermatosis of the folds and Dapsone syndrome on treatment: a case report. Journal of the European Academy of Dermatology and Venereology : JEADV 20080401
Progressive multifocal leukoencephalopathy in a minimally immunosuppressed patient with systemic lupus erythematosus treated with dapsone. The Journal of rheumatology 20080401
A randomized clinical trial comparing safety, clinical and parasitological response to artemether-lumefantrine and chlorproguanil-dapsone in treatment of uncomplicated malaria in pregnancy in Mulago hospital, Uganda. Journal of infection in developing countries 20080401
[Polyarthritis and papular eruption revealing leprosy]. La Revue de medecine interne 20080301
Tacrolimus ointment, an interesting adjunctive therapy for childhood linear IgA bullous dermatosis. Journal of the European Academy of Dermatology and Venereology : JEADV 20080301
Treatment failure with rituximab in a patient with pemphigus vulgaris. Journal of the European Academy of Dermatology and Venereology : JEADV 20080301
[A case of relapsing polychondritis monitored by repeated measurements of flow-volume curve]. Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society 20080301
Development of spray dried liposomal dry powder inhaler of Dapsone. AAPS PharmSciTech 20080301
Immunosuppressive therapy for ocular mucous membrane pemphigoid strategies and outcomes. Ophthalmology 20080201
Otophyma: a case report and review of the literature of lymphedema (elephantiasis) of the ear. The American Journal of dermatopathology 20080201
[Hansen's disease: case report and review of literature]. Revista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia 20080201
[Worsening of leprosy lesions in a Philippine-born patient]. Enfermedades infecciosas y microbiologia clinica 20080201
Efficacy and safety of dapsone gel 5% for the treatment of acne vulgaris in adolescents. Cutis 20080201
Successful treatment of perifolliculitis capitis abscedens et suffodiens with combined isotretinoin and dapsone. Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 20080101
Comment on: Arthritis as presenting manifestation of pure neuritic leprosy--a rheumatologist's dilemma. Rheumatology (Oxford, England) 20080101
An unusual presentation of mucous membrane pemphigoid. Skinmed 20080101
Multicenter randomized, double-blind, placebo-controlled, clinical trial of dapsone as a glucocorticoid-sparing agent in maintenance-phase pemphigus vulgaris. Archives of dermatology 20080101
Treatment of pemphigus: the need for more evidence. Archives of dermatology 20080101
Beneficial effects of word final stress in segmenting a new language: evidence from ERPs. BMC neuroscience 20080101
Open-label comparative clinical study of chlorproguanil-dapsone fixed dose combination (Lapdap) alone or with three different doses of artesunate for uncomplicated Plasmodium falciparum malaria. PloS one 20080101
Urticaria unresponsive to antihistaminic treatment: an open study of therapeutic options based on histopathologic features. The Journal of dermatological treatment 20080101
An open label, randomised trial of artesunate+amodiaquine, artesunate+chlorproguanil-dapsone and artemether-lumefantrine for the treatment of uncomplicated malaria. PloS one 20080101
High risk of severe anaemia after chlorproguanil-dapsone+artesunate antimalarial treatment in patients with G6PD (A-) deficiency. PloS one 20080101
Pyoderma gangrenosum and ulcerative colitis in the tropics. Revista da Sociedade Brasileira de Medicina Tropical 20080101
Effect of arylhydroxylamine metabolites of sulfamethoxazole and dapsone on stress signal expression in human keratinocytes. The Journal of pharmacology and experimental therapeutics 20071201
Successful treatment of relapsing neuro-Sweet's disease with corticosteroid and dapsone combination therapy. Clinical neurology and neurosurgery 20071201
Guiding management in perioperative methemoglobinemia. Minerva anestesiologica 20071201
Pure neural leprosy: steroids prevent neuropathy progression. Arquivos de neuro-psiquiatria 20071201
Nodular scleritis and Sweet's syndrome. Clinical & experimental ophthalmology 20071201
Dapsone induced acute photosensitivity dermatitis; a case report and review of literature. Leprosy review 20071201
Anti-inflammatory and immune therapy for Alzheimer's disease: current status and future directions. Current neuropharmacology 20071201
Pharmacologic advances in the global control and treatment of malaria: combination therapy and resistance. Clinical pharmacology and therapeutics 20071101
Cimetidine and dapsone-mediated methaemoglobinaemia. Anaesthesia 20071101
IgG/IgA pemphigus with dyskeratotic acantholysis and intraepidermal neutrophilic microabscesses. The Journal of dermatology 20071101
Newer topical therapies for the treatment of acne vulgaris. Cutis 20071101
[Sneddon-Wilkinson's subcorneal dermatosis: an atypical case pustular]. La Tunisie medicale 20071101
Improvement of patient tolerance to dapsone: current and future developments. Dermatology online journal 20071013
Hemophagocytic syndrome induced by diaminodiphenylsulfone. The Journal of dermatology 20071001
Epidermolysis bullosa acquisita associated with psoriasis vulgaris. Clinical and experimental dermatology 20070901
Recto-vaginal fistula: a refractory complication of Behcet's disease. Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland 20070901
Detection of haptenated proteins in organotypic human skin explant cultures exposed to dapsone. Drug metabolism and disposition: the biological fate of chemicals 20070901
Interstitial granuloma annulare and borreliosis: a new case. Journal of the European Academy of Dermatology and Venereology : JEADV 20070901
[Long-term follow-up of ofloxacin-combined therapy for leprosy patients]. Nihon Hansenbyo Gakkai zasshi = Japanese journal of leprosy : official organ of the Japanese Leprosy Association 20070901
Immunoglobulin A pemphigus involving the perianal skin and oral mucosa: an unusual presentation. Cutis 20070901
Adverse effects from multi-drug therapy in leprosy: a Brazilian study. Leprosy review 20070901
Leprosy as immune reconstitution inflammatory syndrome in HIV-positive persons. Emerging infectious diseases 20070901
Drug-induced methaemoglobinaemia following elective coronary artery bypass grafting. Anaesthesia 20070701
Age interactions in the development of naturally acquired immunity to Plasmodium falciparum and its clinical presentation. PLoS medicine 20070701
Oxadiazole mannich bases: synthesis and antimycobacterial activity. Bioorganic & medicinal chemistry letters 20070615
Prolonged urticaria with purpura: the spectrum of clinical and histopathologic features in a prospective series of 22 patients exhibiting the clinical features of urticarial vasculitis. Journal of the American Academy of Dermatology 20070601
Generalized vasculitic exanthem following Loxosceles reclusa envenomation. Journal of cutaneous pathology 20070601
Sulfadoxine-pyrimethamine, chlorproguanil-dapsone, or chloroquine for the treatment of Plasmodium vivax malaria in Afghanistan and Pakistan: a randomized controlled trial. JAMA 20070523
Anti-p200 pemphigoid in a 17-year-old girl successfully treated with systemic corticosteroid and dapsone. The British journal of dermatology 20070501
Cutaneous pemphigus vulgaris. Journal of the European Academy of Dermatology and Venereology : JEADV 20070501
Formation and uptake of arylhydroxylamine-haptenated proteins in human dendritic cells. Drug metabolism and disposition: the biological fate of chemicals 20070401
A background and critical analysis of the treatment of pneumocystis carinii pneumonia (PCP) in HIV/AIDS. Australian nursing journal (July 1993) 20070401
Neuroprotective effect of dapsone in patients with acute ischemic stroke: a pilot study. Neurological research 20070401
Use of simple docking methods to screen a virtual library for heteroactivators of cytochrome P450 2C9. Journal of medicinal chemistry 20070322
Total synthesis of azumamide A and azumamide E, evaluation as histone deacetylase inhibitors, and design of a more potent analogue. Organic letters 20070315
An unusual rash in an elderly man. JAAPA : official journal of the American Academy of Physician Assistants 20070301
Leprosy in a preschool child--a case report. Journal of the Indian Medical Association 20070301
Diastereomerically and enantiomerically pure 2,3-disubstituted pyrrolidines from 2,3-aziridin-1-ols using a sulfoxonium ylide: a one-carbon homologative relay ring expansion. Journal of the American Chemical Society 20070221
Treatment of actinomycetoma due to Nocardia spp. with amoxicillin-clavulanate. The British journal of dermatology 20070201
Lepromatous leprosy. Dermatology online journal 20070127
A rapid assay for dihydropteroate synthase activity suitable for identification of inhibitors. Analytical biochemistry 20070115
Annular leukocytoclastic vasculitis in association with chronic hepatitis B. Journal of the European Academy of Dermatology and Venereology : JEADV 20070101
Leprosy. Clinics in dermatology 20070101
Consultative meeting to develop a strategy for treatment of cutaneous leishmaniasis. Institute Pasteur, Paris. 13-15 June, 2006. Kinetoplastid biology and disease 20070101
Therapeutic options for cutaneous leishmaniasis. The Journal of dermatological treatment 20070101
Pharmacokinetics of dapsone gel, 5% for the treatment of acne vulgaris. Clinical pharmacokinetics 20070101
[Multiple autoimmune bullous dermatosis within a family]. Annales de dermatologie et de venereologie 20070101
A overview of ocular leprosy after 2 decades of multidrug therapy. International ophthalmology clinics 20070101
Role of airway lactoperoxidase in scavenging of hydrogen peroxide damage in asthma. Annals of thoracic medicine 20070101
Multidrug therapy regimen for leprosy. Journal of the American Academy of Dermatology 20061201
IgA pemphigus--occurrence of anti-desmocollin 1 and anti-desmoglein 1 antibody reactivity in an individual patient. Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 20061201
Multidrug therapy in leprosy. Journal of the Indian Medical Association 20061201
Effect of conjugated equine estrogens on oxidative metabolism in middle-aged and elderly postmenopausal women. Journal of clinical pharmacology 20061101
Presumed dapsone-induced drug hypersensitivity syndrome causing reversible hypersensitivity myocarditis and thyrotoxicosis. Annals of the Academy of Medicine, Singapore 20061101
[Rosacea fulminans, pyostomatitis and pyovulvitis in Crohn's disease: dapsone as key factor in combination therapy]. Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20061001
Enzyme-mediated protein haptenation of dapsone and sulfamethoxazole in human keratinocytes: II. Expression and role of flavin-containing monooxygenases and peroxidases. The Journal of pharmacology and experimental therapeutics 20061001
Enzyme-mediated protein haptenation of dapsone and sulfamethoxazole in human keratinocytes: I. Expression and role of cytochromes P450. The Journal of pharmacology and experimental therapeutics 20061001
Bioactivation, protein haptenation, and toxicity of sulfamethoxazole and dapsone in normal human dermal fibroblasts. Toxicology and applied pharmacology 20060901
The sulfone syndrome secondary to dapsone prophylaxis in a patient undergoing unrelated hematopoietic stem cell transplantation. Hematological oncology 20060901
Validation of incorporating flurbiprofen into the Pittsburgh cocktail. Clinical pharmacology and therapeutics 20060901
[Guideline for the treatment of Hansen's disease in Japan (Second edition)]. Nihon Hansenbyo Gakkai zasshi = Japanese journal of leprosy : official organ of the Japanese Leprosy Association 20060901
[DNA microarray based rapid drug susceptibility test for Mycobacterium leprae]. Nihon Hansenbyo Gakkai zasshi = Japanese journal of leprosy : official organ of the Japanese Leprosy Association 20060901
[Treating chronic urticaria]. MMW Fortschritte der Medizin 20060803
Anterior ischaemic optic neuropathy associated with Dapsone. Eye (London, England) 20060801
Synthesis and antileprosy activity of some dialkyldithiocarbamates. The Journal of antimicrobial chemotherapy 20060601
Resisting resistance: dealing with the irrepressible problem of malaria. British journal of clinical pharmacology 20060601
Dermatitis herpetiformis and rheumatoid arthritis. Saudi medical journal 20060601
Epidemiology of leprosy and response to treatment in Hong Kong. Hong Kong medical journal = Xianggang yi xue za zhi 20060601
Methemoglobinemia associated with dapsone therapy in a child with pneumonia and chronic immune thrombocytopenic purpura. Journal of pediatric hematology/oncology 20060601
Pneumocystis pneumonia in people with HIV. Clinical evidence 20060601
Chronic inflammatory joint disease revealing borderline leprosy. Joint, bone, spine : revue du rhumatisme 20060501
Microsphere-based protease assays and screening application for lethal factor and factor Xa. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Parasites as causative agents of human affective disorders? The impact of anti-psychotic, mood-stabilizer and anti-parasite medication on Toxoplasma gondii's ability to alter host behaviour. Proceedings. Biological sciences 20060422
Polysulfone-ZrO(2) surface interactions. The influence on formation, morphology and properties of zirfon-membranes. The journal of physical chemistry. B 20060413
Acute methemoglobinemia following attempted suicide by Dapson. Archives of medical research 20060401
Multiple synergistic interactions between atovaquone and antifolates against Plasmodium falciparum in vitro: a rational basis for combination therapy. Acta tropica 20060301
Population pharmacokinetic and pharmacodynamic modelling of the antimalarial chemotherapy chlorproguanil/dapsone. British journal of clinical pharmacology 20060301
Guillain-Barré syndrome-like presentation in borderline leprosy with type-2 reaction. Dermatology online journal 20060227
[Bullous pemphigoid: diagnostics and new therapeutic strategies]. Deutsche medizinische Wochenschrift (1946) 20060224
Remitting seronegative symmetrical synovitis with pitting edema in leprosy. Clinical rheumatology 20060201
First report of leprosy presenting as acute polyarthritis in the setting of type I downgrading lepra reaction. Clinical rheumatology 20060201
Effect of pro-inflammatory cytokines on the toxicity of the arylhydroxylamine metabolites of sulphamethoxazole and dapsone in normal human keratinocytes. Toxicology 20060201
Epidemiology of pemphigus in south-western Iran: a 10-year retrospective study (1991-2000). International journal of dermatology 20060201
[Refractory cutaneous necrotizing vasculitis. Successful sulfone therapy]. Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20060101
Role of human cyclooxygenase-2 in the bioactivation of dapsone and sulfamethoxazole. Drug metabolism and disposition: the biological fate of chemicals 20060101
A case of drug-induced hypersensitivity syndrome showing transient immunosuppression before viral reactivation during treatment for pemphigus foliaceus. Clinical and experimental dermatology 20060101
Childhood lichen planus pemphigoides - a rare entity. Journal of the European Academy of Dermatology and Venereology : JEADV 20060101
Treatment of pemphigus vulgaris. An overview in Mexico. Allergologia et immunopathologia 20060101
Successful treatment of Pyoderma gangrenosum with potassium iodide. Acta dermato-venereologica 20060101
Idiopathic atrophie blanche. Skinmed 20060101
The Dapsone hypersensitivity syndrome revisited: a potentially fatal multisystem disorder with prominent hepatopulmonary manifestations. Journal of occupational medicine and toxicology (London, England) 20060101
[Disulone and hepatosiderosis]. Annales de dermatologie et de venereologie 20060101
Prurigo pigmentosa: an underdiagnosed disease? Indian journal of dermatology, venereology and leprology 20060101
The contribution of prosody to the perception of foreign accent. Phonetica 20060101
An in vitro approach to detect metabolite toxicity due to CYP3A4-dependent bioactivation of xenobiotics. Toxicology 20051215
[Dermopathy and peripheral neuropathy]. Enfermedades infecciosas y microbiologia clinica 20051201
Bullous Systemic Lupus Erythematosus as an Initial Manifestation of SLE. The Journal of dermatology 20051201
Lipids versus proteins as major targets of pro-oxidant, direct-acting hemolytic agents. Toxicological sciences : an official journal of the Society of Toxicology 20051101
Complications related to dapsone use for Pneumocystis jirovecii pneumonia prophylaxis in solid organ transplant recipients. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20051101
Differential antibiotic susceptibilities of starved Mycobacterium tuberculosis isolates. Antimicrobial agents and chemotherapy 20051101
Individual and simultaneous spectrophotometric determination of dapsone and metoclopramide HCl in pharmaceutical dosage forms and synthetic binary mixtures. Chemical & pharmaceutical bulletin 20051101
Presentation of dapsone-induced methemoglobinemia in a patient status post small bowel transplant. Journal of clinical anesthesia 20051101
Protective role of vitamin E on the oxidative stress in Hansen's disease (Leprosy) patients. European journal of clinical nutrition 20051001
Prednisone-free maintenance immunosuppression-a 5-year experience. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20051001
Renal hypersensitivity vasculitis associated with dapsone. American journal of kidney diseases : the official journal of the National Kidney Foundation 20051001
A case of drug-induced hypersensitivity syndrome with multiple organ involvement treated with plasma exchange. Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy 20051001
Twelve-year clinico-therapeutic experience in pemphigus: a retrospective study of 54 cases. International journal of dermatology 20051001
Robust acoustic object detection. The Journal of the Acoustical Society of America 20051001
Childhood bullous pemphigoid successfully treated with diaminodiphenyl sulfone. The Journal of dermatology 20051001
Modeling K(m) values using electrotopological state: substrates for cytochrome P450 3A4-mediated metabolism. Bioorganic & medicinal chemistry letters 20050915
A case of bilateral retinal vasculitis associated with Sweet syndrome. Retina (Philadelphia, Pa.) 20050901
Treatment of bullous pemphigoid with dapsone, methylprednisolone, and topical clobetasol propionate: a retrospective study of 62 cases. Cutis 20050901
Borderline lepromatous leprosy presenting as a single cutaneous plaque. The Australasian journal of dermatology 20050801
Reactive oxygen species generation and its role in the differential cytotoxicity of the arylhydroxylamine metabolites of sulfamethoxazole and dapsone in normal human epidermal keratinocytes. Biochemical pharmacology 20050715
Characterization of the formation and localization of sulfamethoxazole and dapsone-associated drug-protein adducts in human epidermal keratinocytes. The Journal of pharmacology and experimental therapeutics 20050701
Dapsone impairs the bile salt-independent fraction of bile flow in rats: Possible involvement of its N-hydroxylated metabolite. Toxicology 20050701
[Dapsone-induced agranulocytosis. The role of xenobiotic-metabolizing enzymes demonstrated by a case report]. Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20050701
The chemotherapy of rodent malaria. LXIII. Drug combinations to impede the selection of drug resistance, part 6: the potential value of chlorproguanil and dapsone in combination, and with the addition of artesunate. Annals of tropical medicine and parasitology 20050701
Prediction of genotoxicity of chemical compounds by statistical learning methods. Chemical research in toxicology 20050601
Dapsone as a glucocorticoid-sparing agent in maintenance-phase pemphigus vulgaris. Archives of dermatology 20050601
Aplastic anaemia associated with multidrug therapy (dapsone, rifampicin and clofazimine) in a patient with lepromatous leprosy. Leprosy review 20050601
Pneumocystis pneumonia in people with HIV. Clinical evidence 20050601
Malaria: uncomplicated, caused by Plasmodium falciparum. Clinical evidence 20050601
Reduction of sulfamethoxazole and dapsone hydroxylamines by a microsomal enzyme system purified from pig liver and pig and human liver microsomes. Life sciences 20050527
Dapsone suppresses human neutrophil superoxide production and elastase release in a calcium-dependent manner. The British journal of dermatology 20050501
Comparison of colchicine, dapsone, triamcinolone, and diphenhydramine therapy for the treatment of brown recluse spider envenomation: a double-blind, controlled study in a rabbit model. Archives of dermatology 20050501
Safety and success of kidney transplantation and concomitant immunosuppression in HIV-positive patients. Kidney international 20050401
UDP-glucuronosyltransferases and clinical drug-drug interactions. Pharmacology & therapeutics 20050401
Brown recluse spider bites: a complex problem wound. A brief review and case study. Ostomy/wound management 20050301
Artesunate-dapsone-proguanil treatment of falciparum malaria: genotypic determinants of therapeutic response. Transactions of the Royal Society of Tropical Medicine and Hygiene 20050201
Lepromatous iridocyclitis. Ocular immunology and inflammation 20050201
Relationships between nonword repetition accuracy and other measures of linguistic development in children with phonological disorders. Journal of speech, language, and hearing research : JSLHR 20050201
Dapsone syndrome with acute renal failure during leprosy treatment: case report. The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases 20050201
[Successful treatment of subcorneal pustular type of IgA pemphigus]. Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20050101
Simultaneous determination of beta-blocking agents and diuretics in doping analysis by liquid chromatography/mass spectrometry with scan-to-scan polarity switching. Rapid communications in mass spectrometry : RCM 20050101
[Reversible lower limb lymphedema as the first manifestation of cutaneous periarteritis nodosa]. La Revue de medecine interne 20050101
[Pharmacogenetics: Important aspects for dermatology]. Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20050101
[Cicatricial pemphigoid: treatment with mycophenolate mofetil]. Annales de dermatologie et de venereologie 20050101
Raising antibodies in chickens against primaquine, pyrimethamine, dapsone, tetracycline, and doxycycline. Immunological investigations 20050101
Idiopatic angioedema treated with dapsone. Allergologia et immunopathologia 20050101
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Determination of antioxidant activity of some drugs using high-pressure liquid chromatography. Arzneimittel-Forschung 20030101
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[Behcet's disease therapy review]. Anales de medicina interna (Madrid, Spain : 1984) 20021101
[Simultaneous determination of three probe drugs by reversed-phase high performance liquid chromatography]. Se pu = Chinese journal of chromatography 20021101
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Vitamin E for dapsone-induced headache. The British journal of dermatology 20020101
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Update on leprosy. Hospital medicine (London, England : 1998) 20010801
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Response of chronic bullous dermatosis of childhood to a combination of dapsone and nicotinamide. Journal of the European Academy of Dermatology and Venereology : JEADV 20010701
A spectrophotometric method for the determination of metoclopramide HCl and dapsone. Journal of pharmaceutical and biomedical analysis 20010601
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Prevention of invasive aspergillosis in AIDS by sulfamethoxazole. AIDS (London, England) 20010525
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Dapsone-mediated agranulocytosis: risks, possible mechanisms and prevention. Toxicology 20010412
Incidence and determinants of Pseudomonas aeruginosa infection among persons with HIV: association with hospital exposure. American journal of infection control 20010401
Treatment of Behçet's disease--an update. Seminars in arthritis and rheumatism 20010401
The IL-8 release from cultured human keratinocytes, mediated by antibodies to bullous pemphigoid autoantigen 180, is inhibited by dapsone. Clinical and experimental immunology 20010401
Dapsone in treatment of chronic idiopathic thrombocytopenic purpura in adults. The Journal of the Association of Physicians of India 20010401
Eosinophilic pustular folliculitis (Ofuji's disease): indomethacin as a first choice of treatment. Clinical and experimental dermatology 20010301
Dapsone and iminodibenzyl as novel reagents for the spectrophotometric determination of trace amounts of nitrite in water samples. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20010301
Quantifying and documenting prior beliefs in clinical trials. Statistics in medicine 20010227
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Application of higher throughput screening (HTS) inhibition assays to evaluate the interaction of antiparasitic drugs with cytochrome P450s. Drug metabolism and disposition: the biological fate of chemicals 20010101
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Dapsone and sulfapyridine. Dermatologic clinics 20010101
Dapsone-induced photodermatitis in a patient with linear IgA dermatosis. European journal of dermatology : EJD 20010101
A rationale for adjuvant surgical intervention in pyoderma gangrenosum. Annals of plastic surgery 20010101
Hansen's disease in a native-born, United States resident, after a brief stay in an endemic area abroad. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 20010101
Management of patients with severe oral mucosal disease. The Alpha omegan 20010101
Assessment of antioxidant activity of some antileprotic drugs. Arzneimittel-Forschung 20010101
The Malta Project--a country freed itself of leprosy. A 27-year progress study (1972-1999) of the first successful eradication of leprosy. Chemotherapy 20010101
Hepatic and haematological adverse reactions associated with the use of multidrug therapy in leprosy--a five year retrospective study. Indian journal of leprosy 20010101
A trial of proguanil-dapsone in comparison with sulfadoxine-pyrimethamine for the clearance of Plasmodium falciparum infections in Tanzania. Transactions of the Royal Society of Tropical Medicine and Hygiene 20010101
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Leprosy. Recognition and treatment. American journal of clinical dermatology 20010101
Cutaneous drug reaction case reports: from the world literature. American journal of clinical dermatology 20010101
Oxidative stress, glucose-6-phosphate dehydrogenase and the red cell. Advances in experimental medicine and biology 20010101
Lucio leprosy with lucio phenomenon. Indian journal of leprosy 20010101
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Dapsone hypersensitivity syndrome with coexisting acute hepatitis E. Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology 20000101
Treatment of linear IgA bullous dermatosis of childhood with colchicine. Pediatric dermatology 19990101
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Dapsone and liver failure. Nursing 19980101
A previously unrecognised side effect of dapsone. The British journal of ophthalmology 19971201
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Enhanced in vitro activity of WR99210 in combination with dapsone against Mycobacterium avium complex. Antimicrobial agents and chemotherapy 19961101
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In-vitro activity of macrolides alone and in combination with artemisin, atovaquone, dapsone, minocycline or pyrimethamine against Cryptosporidium parvum. The Journal of antimicrobial chemotherapy 19960901
Dapsone- and primaquine-induced methemoglobinemia in HIV-infected individuals. Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association 19960815
Dapsone hypersensitivity syndrome. Journal of the American Academy of Dermatology 19960801
Bioluminescence screening in vitro (Bio-Siv) assays for high-volume antimycobacterial drug discovery. Antimicrobial agents and chemotherapy 19960601
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New antifolate 4,4'-diaminodiphenyl sulfone substituted 2,4-diamino-5-benzylpyrimidines. Proof of their dual mode of action and autosynergism. Archiv der Pharmazie 19960301
New drug developments for opportunistic infections in immunosuppressed patients: Pneumocystis carinii. Journal of medicinal chemistry 19951124
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Effect of atovaquone and atovaquone drug combinations on prophylaxis of Pneumocystis carinii pneumonia in SCID mice. Antimicrobial agents and chemotherapy 19950401
Cimetidine improves the therapeutic/toxic ratio of dapsone in patients on chronic dapsone therapy. The British journal of dermatology 19950201
A pilot study on the efficacy of epiroprim against developmental stages of Toxoplasma gondii and Pneumocystis carinii in animal models. Parasitology research 19950101
Clarithromycin, dapsone, and a combination of both used to treat or prevent disseminated Mycobacterium avium infection in beige mice. Antimicrobial agents and chemotherapy 19941201
Dapsone-induced aplastic anemia in a woman with bullous systemic lupus erythematosus. Mayo Clinic proceedings 19941201
Dapsone therapy causing sulfone syndrome and lethal hepatic failure in an HIV-infected patient. Southern medical journal 19941101
Relative potency of 10 drugs with anti-Pneumocystis carinii activity in an animal model. The Journal of infectious diseases 19941001
Activity of epiroprim (Ro 11-8958), a dihydrofolate reductase inhibitor, alone and in combination with dapsone against Toxoplasma gondii. Antimicrobial agents and chemotherapy 19940801
Screening for glucose-6-phosphate dehydrogenase deficiency prior to dapsone therapy. Clinical and experimental dermatology 19940501
Interaction of Pneumocystis carinii dihydropteroate synthase with sulfonamides and diaminodiphenyl sulfone (dapsone). The Journal of infectious diseases 19940201
Activity of subinhibitory concentrations of dapsone alone and in combination with cell-wall inhibitors against Mycobacterium avium complex organisms. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 19931201
Synergistic combinations of Ro 11-8958 and other dihydrofolate reductase inhibitors with sulfamethoxazole and dapsone for therapy of experimental pneumocystosis. Antimicrobial agents and chemotherapy 19930701
Efficacy and safety of multidrug therapy in paucibacillary leprosy in Singapore. Leprosy review 19930601
Dapsone-associated agranulocytosis and severe anemia in a patient with leukocytoclastic vasculitis. Journal of the American Academy of Dermatology 19930501
Diarylsulfones, a new chemical class of nonnucleoside antiviral inhibitors of human immunodeficiency virus type 1 reverse transcriptase. Antimicrobial agents and chemotherapy 19930401
Dapsone-induced hemolytic anemia: effect of N-hydroxy dapsone on the sulfhydryl status and membrane proteins of rat erythrocytes. Toxicology and applied pharmacology 19921201
Treatment of experimental pneumocystosis: review of 7 years of experience and development of a new system for classifying antimicrobial drugs. Antimicrobial agents and chemotherapy 19920901
Dapsone induced motor polyneuropathy. The Southeast Asian journal of tropical medicine and public health 19920601
Dapsone suppresses integrin-mediated neutrophil adherence function. The Journal of investigative dermatology 19920201
[Granulomatous hepatitis caused by dapsone]. Gastroenterologie clinique et biologique 19920101
[Polyneuropathy in Duhring dermatitis herpetiformis]. Der Nervenarzt 19910801
Gall-bladder perforation after long-term dapsone therapy. Journal of internal medicine 19901001
Inhibition of Pneumocystis carinii dihydropteroate synthetase by sulfa drugs. Antimicrobial agents and chemotherapy 19900601
Interaction of sulfonamide and sulfone compounds with Toxoplasma gondii dihydropteroate synthase. The Journal of clinical investigation 19900201
Manic depression induced by dapsone in patient with dermatitis herpetiformis. BMJ (Clinical research ed.) 19890930
Idiosyncratic dapsone induced manic depression. BMJ (Clinical research ed.) 19890729
Acute dapsone-induced peripheral neuropathy. Muscle & nerve 19890701
Idiosyncratic dapsone induced manic depression. BMJ (Clinical research ed.) 19890603
Dapsone-induced haemolytic anaemia and agranulocytosis in a patient with normal glucose-6-phosphate-dehydrogenase activity. Acta haematologica 19890101
Clinical experience with zidovudine for patients with acquired immune deficiency syndrome and acquired immune deficiency syndrome-related complex. The Journal of infection 19890101
Convulsions associated with prophylactic antimalarial drugs: implications for people with epilepsy. BMJ (Clinical research ed.) 19880820
Efficacy of DL-alpha-difluoromethylornithine in a rat model of Pneumocystis carinii pneumonia. Antimicrobial agents and chemotherapy 19880801
Neurologic symptoms posing as dapsone-induced polyneuropathy in two patients with dermatitis herpetiformis. Cutis 19880501
Comparison of dosages, intervals, and drugs in the prevention of Pneumocystis carinii pneumonia. Antimicrobial agents and chemotherapy 19880501
Role of dapsone hydroxylamine in dapsone-induced hemolytic anemia. The Journal of pharmacology and experimental therapeutics 19880101
Dapsone-associated Heinz body hemolytic anemia in a Cambodian woman with hemoglobin E trait. The American journal of the medical sciences 19871101
Acne fulminans with dapsone induced haemolysis: a case report. The Medical journal of Malaysia 19870601
Dapsone-induced neuropathy compounds Hansen's disease nerve damage: an electrophysiological study in tuberculoid patients. International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association 19870301
Dapsone neuropathy--report of three cases and pathologic features of a motor nerve. International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association 19870301
Dapsone hepatitis. Archives of internal medicine 19870101
Acute renal failure--a complication of new multidrug regimen for treatment of leprosy. International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association 19860901
Dapsone-induced peripheral neuropathy. International journal of dermatology 19860601
Successful treatment and prevention of murine Pneumocystis carinii pneumonitis with 4,4'-sulfonylbisformanilide. Antimicrobial agents and chemotherapy 19860301
Thalidomide therapy. An open trial. International journal of dermatology 19850301
Dapsone and aplastic anemia. Annals of internal medicine 19850101
Rheumatoid arthritis: the effects of treatment with dapsone on hemoglobin. The Journal of rheumatology 19841201
Benzylamines: synthesis and evaluation of antimycobacterial properties. Journal of medicinal chemistry 19840901
[Chronic atrophic polychondritis. Critical analysis of the therapeutic efficacy of dapsone. 2 cases]. Presse medicale (Paris, France : 1983) 19840324
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Toxicity and side-effects of antimalarials in Africa: a critical review. Bulletin of the World Health Organization 19840101
[Role of dapsone in the treatment of Horton's disease and polymyalgia rheumatica]. Annales de medecine interne 19840101
Maloprim-induced agranulocytosis and red-cell aplasia. The Medical journal of Australia 19821201
Hemolytic anemia induced by dapsone transmitted through breast milk. Annals of internal medicine 19820401
Peripheral motor neuropathy caused by excessive intake of dapsone (Avlosulfon). Archiv fur Psychiatrie und Nervenkrankheiten 19820101
[Methemoglobinemia and hemolytic anemia induced by Disulon]. Annales de dermatologie et de venereologie 19820101
Dapsone induced hypohaptoglobinemia in lepromatous leprosy patients. International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association 19810901
Dapsone-induced optic atrophy and motor neuropathy. British medical journal (Clinical research ed.) 19810725
Intra-neural ceroid-like pigment following the treatment of lepromatous leprosy with clofazimine (B663; Lamprene). Journal of neurology, neurosurgery, and psychiatry 19810201
Dapsone haemolysis in leprosy. A preliminary report. Leprosy in India 19810101
Dapsone-induced optic atrophy and motor neuropathy. British medical journal 19801101
Sulphone induced exfoliative dermatitis and hepatitis. Leprosy in India 19800401
Dapsone and nerve damage. Leprosy review 19800301
Intermittent rifampicin therapy in lepromatous leprosy. Leprosy in India 19800101
Studies on dapsone induced haemolytic anaemia. I. Methaemoglobin production and G-6-PD activity in correlation with dapsone dosage. The British journal of dermatology 19790401
Dapsone and renal papillary necrosis. British medical journal 19780114
Dapsone-induced distal axonal degeneration of the motor neurons. Dermatologica 19780101
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Acute renal failure due to intravascular hemolysis in the North Indian patients. The American journal of the medical sciences 19770101
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Dapsone-induced motor polyneuropathy. A complication of prolonged treatment of subcorneal pustular dermatosis. Archives of dermatology 19760801
High dose dapsone toxicity. The British journal of dermatology 19760701
Dapsone motor neuropathy--an axonal disease. Neurology 19760601
Serum hemopexin in patients with dermatitis herpetiformis on dapsone (di(4-aminophenyl)sulphone). Archives for dermatological research = Archiv fur dermatologische Forschung 19751231
Erythema nodosum leprosum in Nigeria. International journal of dermatology 19751101
[In-vitro potentiation of the anti-tuberculous effects of rifampicin and ethionamide by 4,4-diamino-diphenylsulphone (author's transl)]. Praxis der Pneumologie 19750801
[In-vitro study of the effects of 4,4-diamino-diphenylsulphone in combination with isoniazid and rifampicin (author's transl)]. Praxis der Pneumologie 19750801
Glucose-6-phosphate dehydrogenase deficiency and intravascular haemolysis. Irish journal of medical science 19740701
Possible dapsone-induced peripheral neuropathy in dermatitis herpetiformis. Proceedings of the Royal Society of Medicine 19740601
Exacerbation of dapsone-induced Heinz body hemolytic anemia following treatment with methylene blue. The American journal of the medical sciences 19740501
Neurotoxicity of sulfones. Archives of dermatology 19721001
Dapsone-induced peripheral neuropathy. Archives of neurology 19720801
Dapsone induced peripheral neuropathy. The British journal of dermatology 19720501
[Ulcer on white atrophy: hemolytic anemia caused by disulone revealing an erythrocytic glutathione reductase deficiency]. Bulletin de la Societe francaise de dermatologie et de syphiligraphie 19720101
Antileprosy drugs. British medical journal 19711127
Trial of high dosages of dapsone in the treatment of tuberculoid leprosy. Leprosy review 19710601
Anaemia in dermatitis herpetiformis. The role of dapsone-induced haemolysis and malabsorption. The British journal of dermatology 19700401
Dapsone and peripheral motor neuropathy. Archives of dermatology 19690801
Methemoglobinemia provoked by malarial chemoprophylaxis in Vietnam. The New England journal of medicine 19681121
Supplemental sulfone (dapsone) therapy. Use in treatment of chloroquine-resistant falciparum malaria. Archives of internal medicine 19670601
Evaluation of the sulfones and streptomycin in experimental tuberculosis. Annals of the New York Academy of Sciences 19491214
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