Roquinimex
| Title | Journal |
|---|---|
| H1521, a novel derivative of 4-hydroxyquinoline-3-carboxamide, suppresses the development of lupus in mice by inducing Th1 cytokine profile in T cells. | International immunopharmacology 20110401 |
| The long and winding road for the development of tasquinimod as an oral second-generation quinoline-3-carboxamide antiangiogenic drug for the treatment of prostate cancer. | Expert opinion on investigational drugs 20101001 |
| Roquinimex-mediated protection effect on the development of chronic graft-versus-host disease in mice is associated with induction of Th1 cytokine production and inhibition of proinflammatory cytokine production. | Life sciences 20071027 |
| Identification of ABR-215050 as lead second generation quinoline-3-carboxamide anti-angiogenic agent for the treatment of prostate cancer. | The Prostate 20061201 |
| Design, synthesis, and biological evaluation of novel 4-hydro-quinoline-3-carboxamide derivatives as an immunomodulator. | Bioorganic & medicinal chemistry letters 20050615 |
| Effect of Linomide on adhesion molecules, TNF-alpha, nitrogen oxide, and cell adhesion. | International immunopharmacology 20050201 |
| Interleukin-10 mediates the protective effect of Linomide by reducing CXC chemokine production in endotoxin-induced liver injury. | British journal of pharmacology 20041201 |
| Immunomodulation by roquinimex decreases the expression of IL-23 (p19) mRNA in the brains of herpes simplex virus type 1 infected BALB/c mice. | Clinical and experimental immunology 20040801 |
| Synthesis and biological evaluation of new 1,2-dihydro-4-hydroxy-2-oxo-3-quinolinecarboxamides for treatment of autoimmune disorders: structure-activity relationship. | Journal of medicinal chemistry 20040408 |
| Structure-activity relationships studies of the anti-angiogenic activities of linomide. | Bioorganic & medicinal chemistry letters 20030324 |
| Roquinimex inhibits dextran sodium sulfate-induced murine colitis. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20030201 |
| Semliki Forest virus infection is enhanced in Th1-prone SJL mice but not in Th2-prone BALB/c mice during Linomide-induced immunomodulation. | Journal of neuroimmunology 20021101 |
| Quinoline-3-carbothioamides and related compounds as novel immunomodulating agents. | Bioorganic & medicinal chemistry letters 20020902 |
| The new orally active immunoregulator laquinimod (ABR-215062) effectively inhibits development and relapses of experimental autoimmune encephalomyelitis. | Journal of neuroimmunology 20020901 |
| Suppression of experimental autoimmune neuritis by ABR-215062 is associated with altered Th1/Th2 balance and inhibited migration of inflammatory cells into the peripheral nerve tissue. | Neuropharmacology 20020401 |
| Protective effect of Linomide on TNF-alpha-induced hepatic injury. | Journal of hepatology 20020201 |
| Effects of Linomide on immune cells and cytokines inhibit autoimmune pathologies of the central and peripheral nervous system. | International immunopharmacology 20010601 |
| The immunomodulator Linomide: role in treatment and prevention of autoimmune diabetes mellitus. | International immunopharmacology 20010601 |
| Relationship of urinary myelin basic protein-like material with cranial magnetic resonance imaging in advanced multiple sclerosis. | Archives of neurology 20010101 |
| Identification of cytochrome P4503A as the major subfamily responsible for the metabolism of roquinimex in man. | Xenobiotica; the fate of foreign compounds in biological systems 20000901 |