Nvp-bep800
| Title | Journal |
|---|---|
| Targeting conserved water molecules: design of 4-aryl-5-cyanopyrrolo[2,3-d]pyrimidine Hsp90 inhibitors using fragment-based screening and structure-based optimization. | Bioorganic & medicinal chemistry 20121115 |
| Novel HSP90 inhibitors, NVP-AUY922 and NVP-BEP800, radiosensitise tumour cells through cell-cycle impairment, increased DNA damage and repair protraction. | British journal of cancer 20100525 |
| Preclinical antitumor activity of the orally available heat shock protein 90 inhibitor NVP-BEP800. | Molecular cancer therapeutics 20100401 |
| Combining hit identification strategies: fragment-based and in silico approaches to orally active 2-aminothieno[2,3-d]pyrimidine inhibitors of the Hsp90 molecular chaperone. | Journal of medicinal chemistry 20090813 |