Ramiprilate
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Influence of ramiprilat and losartan on ischemia reperfusion injury in rat hearts. | Journal of the renin-angiotensin-aldosterone system : JRAAS 20120301 |
Ramiprilate inhibits functional matrix metalloproteinase activity in Crohn's disease fistulas. | Basic & clinical pharmacology & toxicology 20110901 |
Development and validation of UPLC tandem mass spectrometry assay for separation of a phase II metabolite of ramipril using actual study samples and its application to a bioequivalence study. | Biomedical chromatography : BMC 20110601 |
Impact of methylation of acyl glucuronide metabolites on incurred sample reanalysis evaluation: ramiprilat case study. | Bioanalysis 20110501 |
Simultaneous determination of ramipril, ramiprilat and telmisartan in human plasma using liquid chromatography tandem mass spectrometry. | Talanta 20110115 |
Effects of zofenopril and ramipril on cough reflex responses in anesthetized and awake rabbits. | Journal of cardiovascular pharmacology and therapeutics 20101201 |
Aliskiren versus ramipril in hypertension. | Therapeutic advances in cardiovascular disease 20100601 |
Sensitivity enhancement and matrix effect evaluation during summation of multiple transition pairs-case studies of clopidogrel and ramiprilat. | Biomedical chromatography : BMC 20100501 |
Decreased renal perfusion rapidly increases plasma membrane Na-K-ATPase in rat cortex by an angiotensin II-dependent mechanism. | American journal of physiology. Renal physiology 20091101 |
Bioanalytical method development and validation using incurred samples--simultaneous quantitation of ramipril and ramiprilat in human EDTA plasma by LC-MS/MS. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20091101 |
Pharmacokinetics and pharmacodynamics of ramipril and ramiprilat in healthy cats. | Journal of veterinary pharmacology and therapeutics 20080801 |
Vildagliptin, a novel dipeptidyl peptidase IV inhibitor, has no pharmacokinetic interactions with the antihypertensive agents amlodipine, valsartan, and ramipril in healthy subjects. | Journal of clinical pharmacology 20080101 |
Direct effects of the angiotensin-converting enzyme inhibitor ramiprilat on adult rat ventricular cardiomyocytes. | Acta physiologica (Oxford, England) 20071201 |
Inhibition of angiotensin-converting enzyme reduces rat liver reperfusion injury via bradykinin-2-receptor. | The Journal of surgical research 20060801 |
Interference from a glucuronide metabolite in the determination of ramipril and ramiprilat in human plasma and urine by gas chromatography-mass spectrometry. | Journal of pharmaceutical and biomedical analysis 20060224 |
High-performance liquid chromatography-mass spectrometric analysis of ramipril and its active metabolite ramiprilat in human serum: application to a pharmacokinetic study in the Chinese volunteers. | Journal of pharmaceutical and biomedical analysis 20060213 |
Comparative bioavailability of two ramipril formulations after single-dose administration in healthy volunteers. | International journal of clinical pharmacology and therapeutics 20060201 |
Human physiologically based pharmacokinetic model for ACE inhibitors: ramipril and ramiprilat. | BMC clinical pharmacology 20060101 |
Pharmacokinetic and pharmacodynamic parameters of ramipril and ramiprilat in healthy dogs and dogs with reduced glomerular filtration rate. | Journal of veterinary internal medicine 20060101 |
Modulation of soluble receptor for advanced glycation end products by angiotensin-converting enzyme-1 inhibition in diabetic nephropathy. | Journal of the American Society of Nephrology : JASN 20050801 |
Role of tissue kallikrein in the cardioprotective effects of ischemic and pharmacological preconditioning in myocardial ischemia. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050701 |
Signaling via the angiotensin-converting enzyme enhances the expression of cyclooxygenase-2 in endothelial cells. | Hypertension (Dallas, Tex. : 1979) 20050101 |
ACE inhibition lowers angiotensin-II-induced monocyte adhesion to HUVEC by reduction of p65 translocation and AT 1 expression. | Journal of vascular research 20050101 |
ACE inhibition lowers angiotensin II-induced chemokine expression by reduction of NF-kappaB activity and AT1 receptor expression. | Biochemical and biophysical research communications 20041210 |
Angiotensin-converting enzyme is involved in outside-in signaling in endothelial cells. | Circulation research 20040109 |
Lack of male-female differences in disposition and esterase hydrolysis of ramipril to ramiprilat in healthy volunteers after a single oral dose. | TheScientificWorldJournal 20031211 |
Right ventricular hypertrophy and apoptosis after pulmonary artery banding: regulation of PKC isozymes. | Cardiovascular research 20030901 |
Mechanisms of myocardial remodeling: ramiprilat blocks the expressional upregulation of protein kinase C-epsilon in the surviving myocardium early after infarction. | Journal of cardiovascular pharmacology 20030501 |
Differential effects of saralasin and ramiprilat, the inhibitors of renin-angiotensin system, on cerulein-induced acute pancreatitis. | Regulatory peptides 20030328 |
Effect of ACE-inhibitor ramiprilat and AT1-receptor antagonist candesartan on cardiac norepinephrine release: comparison between ischemic and nonischemic conditions. | Journal of cardiovascular pharmacology 20021001 |
Acute antihypertrophic actions of bradykinin in the rat heart: importance of cyclic GMP. | Hypertension (Dallas, Tex. : 1979) 20021001 |
Simvastatin reverses impaired regulation of renal oxygen consumption in congestive heart failure. | American journal of physiology. Renal physiology 20011101 |
Inhibitors of bradykinin-inactivating enzymes decrease myocardial ischemia/reperfusion injury following 3 and 7 days of reperfusion. | The Journal of pharmacology and experimental therapeutics 20010901 |
Apstatin, a selective inhibitor of aminopeptidase P, reduces myocardial infarct size by a kinin-dependent pathway. | British journal of pharmacology 20010901 |
Bradykinin metabolism in the isolated perfused rabbit heart. | Journal of hypertension 20010701 |
Potentiation of kinin analogues by ramiprilat is exclusively related to their degradation. | Hypertension (Dallas, Tex. : 1979) 20010701 |
Endothelial nitric oxide synthase plays an essential role in regulation of renal oxygen consumption by NO. | American journal of physiology. Renal physiology 20010501 |
Modulation of renal oxygen consumption by nitric oxide is impaired after development of congestive heart failure in dogs. | Journal of cardiovascular pharmacology 20010301 |
Potential role of eNOS in the therapeutic control of myocardial oxygen consumption by ACE inhibitors and amlodipine. | Cardiovascular research 20010101 |
ACE inhibitor and AT1 antagonist blockade of deformation-induced gene expression in the rabbit jugular vein through B2 receptor activation. | Arteriosclerosis, thrombosis, and vascular biology 20010101 |
Neuropeptide Y enhances potassium excretion by mechanisms distinct from those controlling sodium excretion. | Canadian journal of physiology and pharmacology 20000201 |
Role of nitric oxide in the control of cardiac oxygen consumption in B(2)-kinin receptor knockout mice. | Hypertension (Dallas, Tex. : 1979) 19991001 |
Synergy of amlodipine and angiotensin-converting enzyme inhibitors in regulating myocardial oxygen consumption in normal canine and failing human hearts. | The American journal of cardiology 19990617 |
Ramiprilat attenuates hypoxia/reoxygenation injury to cardiac myocytes via a bradykinin-dependent mechanism. | European journal of pharmacology 19960613 |
[Cardioprotective effects by ramipril after ischemia and reperfusion in animal experiment studies]. | Zeitschrift fur Kardiologie 19940101 |
Cardiac arrhythmias are ameliorated by local inhibition of angiotensin formation and bradykinin degradation with the converting-enzyme inhibitor ramipril. | Cardiovascular drugs and therapy 19891201 |
2-[N-[(S)-1-ethoxycarbonyl-3-phenylpropyl]-L-alanyl]-(1S,3S,5S) -2-azabicyclo[3.3.0]octane-3-carboxylic acid (Hoe 498)--a new and highly effective angiotensin I converting enzyme inhibitor. | Arzneimittel-Forschung 19840101 |