Pf-915275
| Title | Journal |
|---|---|
| Cortisol and interferon tau regulation of endometrial function and conceptus development in female sheep. | Endocrinology 20130201 |
| Will treating diabetes with 11β-HSD1 inhibitors affect the HPA axis? | Trends in endocrinology and metabolism: TEM 20101001 |
| Efficacious 11beta-hydroxysteroid dehydrogenase type I inhibitors in the diet-induced obesity mouse model. | Journal of medicinal chemistry 20090910 |
| N-(Pyridin-2-yl) arylsulfonamide inhibitors of 11beta-hydroxysteroid dehydrogenase type 1: Discovery of PF-915275. | Bioorganic & medicinal chemistry letters 20090701 |
| Blockade of glucocorticoid excess at the tissue level: inhibitors of 11beta-hydroxysteroid dehydrogenase type 1 as a therapy for type 2 diabetes. | Journal of medicinal chemistry 20080828 |
| Modulation of 11beta-hydroxysteroid dehydrogenase (11betaHSD) activity biomarkers and pharmacokinetics of PF-00915275, a selective 11betaHSD1 inhibitor. | The Journal of clinical endocrinology and metabolism 20080201 |
| Demonstration of proof of mechanism and pharmacokinetics and pharmacodynamic relationship with 4'-cyano-biphenyl-4-sulfonic acid (6-amino-pyridin-2-yl)-amide (PF-915275), an inhibitor of 11 -hydroxysteroid dehydrogenase type 1, in cynomolgus monkeys. | The Journal of pharmacology and experimental therapeutics 20080101 |
| Induction of 11β-HSD 1 and activation of distinct mineralocorticoid receptor- and glucocorticoid receptor-dependent gene networks in decidualizing human endometrial stromal cells. | Molecular endocrinology (Baltimore, Md.) |