Inhibition of uterine contractility with various tocolytics with and without progesterone: in vitro studies.

American journal of obstetrics and gynecology 20120301

Properties and functions of KATP during mouse perinatal development.

Biochemical and biophysical research communications 20120203

Hypoxia and reoxygenation modulate the arrhythmogenic activity of the pulmonary vein and atrium.

Clinical science (London, England : 1979) 20120201

[The changes of metabolism in myocardium at ischemia-reperfusion and activating of the ATP-sensitive potassium channels].

Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20120101

Vasodilation of retinal arterioles induced by activation of BKCa channels is attenuated in diabetic rats.

European journal of pharmacology 20111101

Vasodilation induced by oxygen/glucose deprivation is attenuated in cerebral arteries of SUR2 null mice.

American journal of physiology. Heart and circulatory physiology 20111001

Agonist-induced periodic vasomotion in rat isolated pulmonary artery.

Fundamental & clinical pharmacology 20110801

Effects of potassium channel modulators on myogenic spontaneous phasic contractile activity in human detrusor from neurogenic patients.

BJU international 20110801

Effects of KATP channel openers diazoxide and pinacidil in coronary-perfused atria and ventricles from failing and non-failing human hearts.

Journal of molecular and cellular cardiology 20110801

Ontogeny of sulfonylurea-binding regulatory subunits of K(ATP) channels in the pregnant rat myometrium.

Reproduction (Cambridge, England) 20110701

Modulation of the 6-position of benzopyran derivatives and inhibitory effects on the insulin releasing process.

Bioorganic & medicinal chemistry 20110701

Hydrogen sulfide dilates cerebral arterioles by activating smooth muscle cell plasma membrane KATP channels.

American journal of physiology. Heart and circulatory physiology 20110601

Inhibitory effect of caffeine on pacemaker activity in the oviduct is mediated by cAMP-regulated conductances.

British journal of pharmacology 20110601

Effect of potassium channel opener pinacidil on the contractions elicited electrically or by noradrenaline in the human radial artery.

European journal of pharmacology 20110311

Cirrhosis decreases vasoconstrictor response to electrical field stimulation in rat mesenteric artery: role of calcitonin gene-related peptide.

Experimental physiology 20110301

Participation of BKCa2+ and KATP potassium ion channels in the contractility of human term pregnant myometrium in in vitro conditions.

The journal of obstetrics and gynaecology research 20110301

Sarcolemmal cardiac K(ATP) channels as a target for the cardioprotective effects of the fluorine-containing pinacidil analogue, flocalin.

British journal of pharmacology 20110201

Role of vascular K(ATP) channels in blood pressure variability after sinoaortic denervation in rats.

Acta pharmacologica Sinica 20110201

Activation of ATP-sensitive potassium channels antagonize nociceptive behavior and hyperexcitability of DRG neurons from rats.

Molecular pain 20110101

[Ontogeny of sulphonylurea-binding regulatory subunits of K(ATP) channels in the pregnant rat myometrium].

Acta pharmaceutica Hungarica 20110101

Both mitochondrial KATP channel opening and sarcolemmal KATP channel blockage confer protection against ischemia/reperfusion-induced arrhythmia in anesthetized male rats.

Journal of cardiovascular pharmacology and therapeutics 20101201

Diazoxide maintenance of myocyte volume and contractility during stress: evidence for a non-sarcolemmal K(ATP) channel location.

The Journal of thoracic and cardiovascular surgery 20101101

Effects of K openers on the QT prolongation induced by HERG-blocking drugs in guinea-pigs.

The Journal of pharmacy and pharmacology 20100701

A study of the relationship between pharmacologic preconditioning and adenosine triphosphate-sensitive potassium (KATP) channels on cultured cardiomyocytes using the microelectrode array.

Journal of cardiovascular pharmacology 20100701

Genotype-phenotype correlation in tissue models of Brugada syndrome simulating patients with sodium and calcium channelopathies.

Heart rhythm 20100601

Hydrogen sulfide attenuates epithelial-mesenchymal transition of human alveolar epithelial cells.

Pharmacological research 20100401

Prolonged donor heart preservation with pinacidil: the role of mitochondria and the mitochondrial adenosine triphosphate-sensitive potassium channel.

The Journal of thoracic and cardiovascular surgery 20100401

Pinacidil-primed ATP-sensitive potassium channels mediate feedback control of mechanical power output in isolated myocardium of rats and guinea pigs.

European journal of pharmacology 20100225

K(ATP) channel openers protect mesencephalic neurons against MPP+-induced cytotoxicity via inhibition of ROS production.

Journal of neuroscience research 20100201

Inhibition of oxygen consumption in skeletal muscle-derived mitochondria by pinacidil, diazoxide, and glibenclamide, but not by 5-hydroxydecanoate.

Journal of bioenergetics and biomembranes 20100201

Pharmacological stimulation and inhibition of insulin secretion in mouse islets lacking ATP-sensitive K+ channels.

British journal of pharmacology 20100201

Lipopolysaccharides up-regulate Kir6.1/SUR2B channel expression and enhance vascular KATP channel activity via NF-kappaB-dependent signaling.

The Journal of biological chemistry 20100129

Differential K(ATP) channel pharmacology in intact mouse heart.

Journal of molecular and cellular cardiology 20100101

Hydrogen sulfide opens the KATP channel on rat atrial and ventricular myocytes.

Cardiology 20100101

Direct effects of K(ATP) channel openers pinacidil and diazoxide on oxidative phosphorylation of mitochondria in situ.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20100101

Effects of nicorandil on the cAMP-dependent Cl- current in guinea-pig ventricular cells.

Journal of pharmacological sciences 20100101

Effects of imatinib mesylate in interstitial cells of Cajal from murine small intestine.

Biological & pharmaceutical bulletin 20100101

[Effect of a new activator of adenosine triphosphate-sensitive potassium channels flocalin on the glucose level in blood].

Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20100101

New R/S-3,4-dihydro-2,2-dimethyl-2H-1-benzopyrans as K(ATP) channel openers: modulation of the 4-position.

Bioorganic & medicinal chemistry 20091115

Excitotoxicity in rat's brain induced by exposure of manganese and neuroprotective effects of pinacidil and nimodipine.

Biological trace element research 20091101

Interstitial cells of Cajal generate spontaneous transient depolarizations in the rat gastric fundus.

American journal of physiology. Gastrointestinal and liver physiology 20091001

Endogenous and exogenous hydrogen sulfide promotes resolution of colitis in rats.

Gastroenterology 20090801

Caveolin-3 negatively regulates recombinant cardiac K(ATP) channels.

Biochemical and biophysical research communications 20090731

The phenomenon of seasonal pseudohypokalemia: effects of ambient temperature, plasma glucose and role for sodium-potassium-exchanging-ATPase.

Clinical biochemistry 20090601

Effect of ATP-sensitive potassium channel agonists on sympathetic hyperinnervation in postinfarcted rat hearts.

American journal of physiology. Heart and circulatory physiology 20090601

Functional K(ATP) channels in the rat retinal microvasculature: topographical distribution, redox regulation, spermine modulation and diabetic alteration.

The Journal of physiology 20090515

Loss of functional K+ channels encoded by ether-à-go-go-related genes in mouse myometrium prior to labour onset.

The Journal of physiology 20090515

Molecular and functional characterization of a new potassium conductance in mouse ventricular fibroblasts.

Journal of molecular and cellular cardiology 20090401

Regulation of ATP-sensitive K+ channels by caveolin-enriched microdomains in cardiac myocytes.

Cardiovascular research 20090401

Blockade of K(ATP) channels reduces endothelial hyperpolarization and leukocyte recruitment upon reperfusion after hypoxia.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20090401

Dispersion of repolarization and arrhythmogenesis.

Heart rhythm 20090401

Restitution, heterogeneity and unidirectional conduction block: New roles for old players.

Heart rhythm 20090401

Pinacidil relaxing effect on phenylephrine-precontracted guinea pig aorta was abolished by pretreatment with 17-beta-estradiol.

International journal of cardiology 20090320

Downregulation of Kir6.1/SUR2B channels in the obese rat aorta.

Nutrition (Burbank, Los Angeles County, Calif.) 20090301

The use of microelectrode array (MEA) to study the protective effects of potassium channel openers on metabolically compromised HL-1 cardiomyocytes.

Physiological measurement 20090201

Contribution of RhoA kinase and protein kinase C to weak relaxant effect of pinacidil on carbachol-induced contractions in sensitized guinea-pig trachealis.

Archives of pharmacal research 20090201

[Effect of adenosine triphosphate-dependent potassium channel activators on electrical reactions of intact and cultured endothelial cells].

Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20090101

The influence of animal species on the relationship between ATP-sensitive potassium ion channels and defense reflexes of the airways.

Bratislavske lekarske listy 20090101

Dissection of two Cx37-independent conducted vasodilator mechanisms by deletion of Cx40: electrotonic versus regenerative conduction.

American journal of physiology. Heart and circulatory physiology 20081101

Insulin-like growth factor-I inhibits rat arterial K(ATP) channels through pI 3-kinase.

Biochemical and biophysical research communications 20081003

K+ channel inhibition modulates the biochemical and morphological differentiation of human placental cytotrophoblast cells in vitro.

American journal of physiology. Regulatory, integrative and comparative physiology 20081001

Sulfonylurea receptor-dependent and -independent pathways mediate vasodilation induced by ATP-sensitive K+ channel openers.

Molecular pharmacology 20080901

Opening of microglial K(ATP) channels inhibits rotenone-induced neuroinflammation.

Journal of cellular and molecular medicine 20080901

Activated Rho/Rho kinase and modified calcium sensitivity in cryopreserved human saphenous veins.

Cryobiology 20080801

Decreased expression of aortic KIR6.1 and SUR2B in hypertension does not correlate with changes in the functional role of K(ATP) channels.

European journal of pharmacology 20080610

Role of sarcolemmal ATP-sensitive K+ channels in the regulation of sinoatrial node automaticity: an evaluation using Kir6.2-deficient mice.

The Journal of physiology 20080601

New R/S-3,4-dihydro-2,2-dimethyl-6-halo-4-(phenylaminothiocarbonylamino)-2H-1-benzopyrans structurally related to (+/-)-cromakalim as tissue-selective pancreatic beta-cell K(ATP) channel openers.

Bioorganic & medicinal chemistry 20080515

K(ATP) channel expression and pharmacological in vivo and in vitro studies of the K(ATP) channel blocker PNU-37883A in rat middle meningeal arteries.

British journal of pharmacology 20080501

KATP channel openers have opposite effects on mitochondrial respiration under different energetic conditions.

Journal of cardiovascular pharmacology 20080501

Upregulation of ATP-sensitive potassium channels for estrogen-mediated cell proliferation in human uterine leiomyoma cells.

Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20080501

Protective effect of melatonin on Ca2+ homeostasis and contractility in acute cholecystitis.

Journal of pineal research 20080401

Effect of ATP-sensitive potassium channel agonists on ventricular remodeling in healed rat infarcts.

Journal of the American College of Cardiology 20080401

Evaluation of myorelaxant activity of 7-substituted hexahydroquinoline derivatives in isolated rabbit gastric fundus.

European journal of medicinal chemistry 20080301

Diclofenac exerts local anesthetic-like actions on rat masseter muscle afferent fibers.

Brain research 20080215

Brazilein-induced contraction of rat arterial smooth muscle involves activation of Ca2+ entry and ROK, ERK pathways.

European journal of pharmacology 20080212

Vasodilator effects of adenosine on retinal arterioles in streptozotocin-induced diabetic rats.

Naunyn-Schmiedeberg's archives of pharmacology 20080201

Inhibitory effects of different ATP-sensitive potassium channel openers on electrically generated and carbachol-induced contractions of porcine and human detrusor muscle.

Fundamental & clinical pharmacology 20080201

Treatment for periodic paralysis.

The Cochrane database of systematic reviews 20080123

Iptakalim inhibited endothelin-1-induced proliferation of human pulmonary arterial smooth muscle cells through the activation of K(ATP) channel.

Vascular pharmacology 20080101

Synthesis of 2-methyl-4-aryl-4,6,7,8-tetrahydro-5(1H)-quinolone derivatives and their effects on potassium channels.

Arzneimittel-Forschung 20080101

[Cardioprotective effects of flokalin: relative role of activation of sarcolemmal and mitochondrial adenosine triphosphate-dependent potassium channels].

Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20080101

Effect of pravastatin on sympathetic reinnervation in postinfarcted rats.

American journal of physiology. Heart and circulatory physiology 20071201

KATP channels confer survival advantage in cocaine overdose.

Molecular psychiatry 20071201

Effects of prostaglandin E1 on vascular ATP-sensitive potassium channels.

Journal of cardiovascular pharmacology 20071201

Voltage-gated Ca2+ currents are necessary for slow-wave propagation in the canine gastric antrum.

American journal of physiology. Cell physiology 20071101

The role of potassium ion channels in cough and other reflexes of the airways.

Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20071101

Angiotensin II-activated protein kinase C targets caveolae to inhibit aortic ATP-sensitive potassium channels.

Cardiovascular research 20071001

Involvement of KATP and KvLQT1 K+ channels in EGF-stimulated alveolar epithelial cell repair processes.

American journal of physiology. Lung cellular and molecular physiology 20071001

The effect of potassium channel opener pinacidil on the non-pregnant rat uterus.

Basic & clinical pharmacology & toxicology 20070901

Effects of extracellular HCO3(-) on fatigue, pHi, and K+ efflux in rat skeletal muscles.

Journal of applied physiology (Bethesda, Md. : 1985) 20070801

Spontaneous oscillatory contractions in aortas of rats with arterial pressure lability caused by sinoaortic denervation.

Clinical and experimental pharmacology & physiology 20070801

ATP-sensitive potassium channel: a novel target for protection against UV-induced human skin cell damage.

Journal of cellular physiology 20070701

Arginine vasopressin inhibits Kir6.1/SUR2B channel and constricts the mesenteric artery via V1a receptor and protein kinase C.

American journal of physiology. Regulatory, integrative and comparative physiology 20070701

Vasodilator effect of nicorandil on retinal blood vessels in rats.

Naunyn-Schmiedeberg's archives of pharmacology 20070701

Effect of K+ATP channel and adenosine receptor blockade during rest and exercise in congestive heart failure.

Circulation research 20070608

Role of L-type calcium channels and PKC in active tone development in rabbit coronary artery.

American journal of physiology. Heart and circulatory physiology 20070601

Verrucotoxin inhibits KATP channels in cardiac myocytes through a muscarinic M3 receptor-PKC pathway.

European journal of pharmacology 20070601

Inhibition of KATP channels in the rat tail artery by neurally released noradrenaline acting on postjunctional alpha2-adrenoceptors.

The Journal of physiology 20070601

Reduction of dispersion of repolarization and prolongation of postrepolarization refractoriness explain the antiarrhythmic effects of quinidine in a model of short QT syndrome.

Journal of cardiovascular electrophysiology 20070601

Potassium channel opener pinacidil induces relaxation of the isolated human radial artery.

Journal of pharmacological sciences 20070601

[Effects of preconditioning on the responsiveness of superior mesenteric artery after hemorrhagic shock in rats].

Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue 20070501

Pinacidil reduces neuronal apoptosis following cerebral ischemia-reperfusion in rats through both mitochondrial and death-receptor signal pathways.

Neuroscience bulletin 20070501

Hypotonic stress enhances slope conductivity of ATP-sensitive K+ channels activated pharmacologically.

International journal of cardiology 20070404

ATP-sensitive potassium channels expressed by human monocytes play a role in stasis-induced thrombogenesis via tissue factor pathway.

Life sciences 20070220

Electrophysiological and pharmacological characterization of the K(ATP) channel involved in the K+-current responses to FSH and adenosine in the follicular cells of Xenopus oocyte.

The journal of physiological sciences : JPS 20070201

Effect of KATP channel openers on myogenic and neurogenic responses in goat urinary bladder.

Indian journal of experimental biology 20070201

Identification of two types of ATP-sensitive K+ channels in rat ventricular myocytes.

Life sciences 20070102

Differences in arrhythmogenicity between the canine right ventricular outflow tract and anteroinferior right ventricle in a model of Brugada syndrome.

Heart rhythm 20070101

[Comparative study of the effects of new fluorine-containing pinacidyl analogs on bladder contractile function and vessel tone].

Eksperimental'naia i klinicheskaia farmakologiia 20070101

Role of ATP-dependent potassium channels in pulmonary vascular tone of fetal lambs with congenital diaphragmatic hernia.

Pediatric research 20061101

A key role for the subunit SUR2B in the preferential activation of vascular KATP channels by isoflurane.

British journal of pharmacology 20061101

Actions of ZD0947, a novel ATP-sensitive K+ channel opener, on membrane currents in human detrusor myocytes.

British journal of pharmacology 20061101

Selective inhibition of pinacidil effects by estrogen in guinea pig heart.

International journal of cardiology 20060607

K(+)-evoked [(3)H]-norepinephrine release in human brain slices from epileptic and non-epileptic patients is differentially modulated by gabapentin and pinacidil.

Neuroscience research 20060601

Effects of anthocyanidin derivative (HK-008) on relaxation in rat perfused mesenterial bed.

Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi 20060601

Cellular basis for trigger and maintenance of ventricular fibrillation in the Brugada syndrome model: high-resolution optical mapping study.

Journal of the American College of Cardiology 20060516

Effects of systemic administration of iptakalim on extracellular neurotransmitter levels in the striatum of unilateral 6-hydroxydopamine-lesioned rats.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20060501

Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Cocaine-induced inhibition of ATP-sensitive K+ channels in rat ventricular myocytes and in heart-derived H9c2 cells.

Basic & clinical pharmacology & toxicology 20060501

Action of imipramine on activated ATP-sensitive K(+) channels in interstitial cells of Cajal from murine small intestine.

Life sciences 20060411

Dimethyl lithospermate B, an extract of Danshen, suppresses arrhythmogenesis associated with the Brugada syndrome.

Circulation 20060321

Impact of in vivo preconditioning by isoflurane on adenosine triphosphate-sensitive potassium channels in the rat heart: lasting modulation of nucleotide sensitivity during early memory period.

Anesthesiology 20060301

In vivo characterization of monolithic matrix type transdermal drug delivery systems of pinacidil monohydrate: a technical note.

AAPS PharmSciTech 20060301

The nitric oxide-cyclic GMP-protein kinase G-K+ channel pathway participates in the antiallodynic effect of spinal gabapentin.

European journal of pharmacology 20060215

The regulation of rotenone-induced inflammatory factor production by ATP-sensitive potassium channel expressed in BV-2 cells.

Neuroscience letters 20060213

Loss of mitochondrial membrane potential is associated with increase in mitochondrial volume: physiological role in neurones.

Journal of cellular physiology 20060201

Adenosine- and hypoxia-induced dilation of human coronary resistance arteries: evidence against the involvement of K(ATP) channels.

British journal of pharmacology 20060201

Involvement of potassium channels in hypoglycemic effect of sertraline.

Indian journal of experimental biology 20060201

KATP channels in mouse spermatogenic cells and sperm, and their role in capacitation.

Developmental biology 20060115

Initiation of remote microvascular preconditioning requires K(ATP) channel activity.

American journal of physiology. Heart and circulatory physiology 20060101

Effects of pharmacological modulation of the ATP-sensitive potassium channels on the development of warm-up angina pectoris.

Cardiology 20060101

Relaxant responses to calcium channel antagonists and potassium channel opener in human saphenous vein.

Autonomic & autacoid pharmacology 20060101

The cardioprotective peptide, urocortin, activates cardiac KATP channels in adult rat.

Protein and peptide letters 20060101

Analysis of responses to kava kava in the feline pulmonary vascular bed.

Journal of medicinal food 20060101

Investigation of the relaxant effects of pinacidil and cromakalim on the sheep sphincter of Oddi.

Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 20060101

Electrotonic transmission within pericyte-containing retinal microvessels.

Microcirculation (New York, N.Y. : 1994) 20060101

[Effects of ATP-regulated potassium channels modulators, N-(2-pyridyl)-N'-(4-toluol) sulfonylcarbamides, on electromechanical activity in guinea pig myocardium].

Medicina (Kaunas, Lithuania) 20060101

[Correction of mitochondrial respiration processes in rats with different resistance to hypoxia under stress by modulators of ATP-sensitive potassium channels].

Biomeditsinskaia khimiia 20060101

KATP channel conductance of descending vasa recta pericytes.

American journal of physiology. Renal physiology 20051201

Evidence that activation following failed defibrillation is not caused by triggered activity.

Journal of cardiovascular electrophysiology 20051101

The puzzle of defibrillation: putting the pieces together.

Journal of cardiovascular electrophysiology 20051101

Characterization of K(ATP)-channels in rat basilar and middle cerebral arteries: studies of vasomotor responses and mRNA expression.

European journal of pharmacology 20051031

Effects of pine needle extract on pacemaker currents in interstitial cells of Cajal from the murine small intestine.

Molecules and cells 20051031

Reduced effectiveness of HMR 1098 in blocking cardiac sarcolemmal K(ATP) channels during metabolic stress.

Journal of molecular and cellular cardiology 20051001

Glibenclamide reveals role for endothelin in hypoxia-induced vasoconstriction in rat intrapulmonary arteries.

Journal of cardiovascular pharmacology 20051001

[Effects of iptakalim on intracellular calcium concentrations, PKA and PKC activities in rat tail artery smooth muscle cells].

Yao xue xue bao = Acta pharmaceutica Sinica 20051001

Progress towards a more physiologic approach to donor heart preservation: the advantages of hyperpolarized arrest.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20050901

Effects of calcium channel blocker, mibefradil, and potassium channel opener, pinacidil, on the contractile response of mid-pregnant goat myometrium.

Indian journal of experimental biology 20050901

2-(1-Hexyn-1-yl)adenosine-induced intraocular hypertension is mediated via K+ channel opening through adenosine A2A receptor in rabbits.

European journal of pharmacology 20050822

Effect of thimerosal on arrhythmia induced by coronary ligation: the involvement of ATP-dependent potassium channels.

International heart journal 20050701

Fasudil prevents KATP channel-induced improvement in postischemic functional recovery.

American journal of physiology. Heart and circulatory physiology 20050601

SUR, ABC proteins targeted by KATP channel openers.

Journal of molecular and cellular cardiology 20050601

Effect of the ATP-sensitive potassium channel opener ZM226600 on cystometric parameters in rats with ligature-intact, partial urethral obstruction.

European journal of pharmacology 20050523

Doxapram stimulates the carotid body via a different mechanism than hypoxic chemotransduction.

Respiratory physiology & neurobiology 20050512

Pretreatment with pinacidil promotes arrhythmias in an isolated tissue model of cardiac ischemia and reperfusion.

The Journal of pharmacology and experimental therapeutics 20050501

150-kD oxygen-regulated protein is an essential factor for insulin release.

Pancreas 20050501

Effects of pinacidil on proliferation of cultured rabbit airway smooth muscle cells induced by endothelin-1.

Chinese medical journal 20050405

Role of KATP channels in the regulation of rat dura and pia artery diameter.

Cephalalgia : an international journal of headache 20050401

[Effects of quinidine on pinacidil-induced transmural dispersion of repolarization in canine right ventricular wall].

Zhonghua xin xue guan bing za zhi 20050401

Pacemaker potentials generated by interstitial cells of Cajal in the murine intestine.

American journal of physiology. Cell physiology 20050301

Endothelin-1 acts via protein kinase C to block KATP channels in rabbit coronary and pulmonary arterial smooth muscle cells.

Journal of cardiovascular pharmacology 20050201

[Regulatory effects of nucleotides on ATP-sensitive potassium channel opener pinacidil-induced vascular relaxation].

Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20050201

Reciprocal changes in endothelium-derived hyperpolarizing factor- and nitric oxide-system in the mesenteric artery of adult female rats following ovariectomy.

British journal of pharmacology 20050101

Alteration of binding sites for [3H]P1075 and [3H]glibenclamide in renovascular hypertensive rat aorta.

Acta pharmacologica Sinica 20050101

[The comparative study of the effect of new fluorine-containing guanidine-derivate compounds and pinacidil on contractile function of the urinary bladder in vitro].

Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20050101

Pinacidil increases diclofenac antinociception in the formalin test.

Proceedings of the Western Pharmacology Society 20050101

[Effect of adenosine triphosphate-sensitve potassium channel activator flokalin on the isolated heart functions].

Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20050101

Voltage dependence of ATP-dependent K+ current in rat cardiac myocytes is affected by IK1 and IK(ACh).

The Journal of physiology 20041201

KATP-channel-induced vasodilation is modulated by the Na,K-pump activity in rabbit coronary small arteries.

British journal of pharmacology 20041201

[Iptakalim enhances astrocytic glutamate uptake activity].

Yao xue xue bao = Acta pharmaceutica Sinica 20041201

Caveolae localize protein kinase A signaling to arterial ATP-sensitive potassium channels.

Circulation research 20041112

Testosterone induces cytoprotection by activating ATP-sensitive K+ channels in the cardiac mitochondrial inner membrane.

Circulation 20041109

Pinacidil improves contractile function and intracellular calcium handling in isolated cardiac myocytes exposed to simulated cardioplegic arrest.

The Annals of thoracic surgery 20040901

Donor heart preservation with pinacidil: the role of the mitochondrial K ATP channel.

The Annals of thoracic surgery 20040801

A novel mechanism of regulation of cardiac contractility by mitochondrial functional state.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20040801

Fabrication and evaluation of polymeric films for transdermal delivery of pinacidil.

Die Pharmazie 20040801

Evaluation of antipruritic effects of several agents on scratching behavior by NC/Nga mice.

European journal of pharmacology 20040714

ATP-sensitive potassium channels are involved in adenosine-induced reduction of blood pressure variability in spontaneously hypertensive rats.

Journal of cardiovascular pharmacology 20040701

Potassium channel openers are uncoupling protonophores: implication in cardioprotection.

FEBS letters 20040618

Hypotonic stress increases efficacy of rilmakalim, but not pinacidil, to activate ATP-sensitive K(+) current in guinea pig ventricular myocytes.

Journal of pharmacological sciences 20040601

Cardiovascular effects of the toxin(s) of the Australian paralysis tick, Ixodes holocyclus, in the rat.

Toxicon : official journal of the International Society on Toxinology 20040601

Endothelium-derived hyperpolarizing factor-mediated renal vasodilatory response is impaired during acute and chronic hyperhomocysteinemia.

Circulation 20040518

Molecular identity and function in transepithelial transport of K(ATP) channels in alveolar epithelial cells.

American journal of physiology. Lung cellular and molecular physiology 20040501

Potassium channel dysfunction in cerebral arteries of insulin-resistant rats is mediated by reactive oxygen species.

Stroke 20040401

Pharmacological modulation of the ATP sensitive potassium channels during repeated coronary occlusions: no effect on myocardial ischaemia or function.

Heart (British Cardiac Society) 20040401

Pharmacological activation of plasma-membrane KATP channels reduces reoxygenation-induced Ca(2+) overload in cardiac myocytes via modulation of the diastolic membrane potential.

British journal of pharmacology 20040301

Isoflurane and sevoflurane precondition against neutrophil-induced contractile dysfunction in isolated rat hearts.

Anesthesiology 20040301

Contribution of reactive oxygen species to isoflurane-induced sensitization of cardiac sarcolemmal adenosine triphosphate-sensitive potassium channel to pinacidil.

Anesthesiology 20040301

Uncomplicated rapid posthypothermic rewarming alters cerebrovascular responsiveness.

Stroke 20040201

Molecular mechanisms of the inhibitory effects of propofol and thiamylal on sarcolemmal adenosine triphosphate-sensitive potassium channels.

Anesthesiology 20040201

Mechanism of ST elevation and ventricular arrhythmias in an experimental Brugada syndrome model.

Circulation 20040106

Unusual effects of a QT-prolonging drug, arsenic trioxide, on cardiac potassium currents.

Circulation 20040106

Analysis of responses to St. John's Wort in the feline pulmonary vascular bed.

Journal of herbal pharmacotherapy 20040101

[Effect of K-ATP channel opener-pinacidil on the liver mitochondria function in rats with different resistance to hypoxia during stress].

Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20040101

Analysis of responses to valerian root extract in the feline pulmonary vascular bed.

Journal of alternative and complementary medicine (New York, N.Y.) 20031201

Nicorandil inhibits the release of TNFalpha from a lymphocyte cell line and peripheral blood lymphocytes.

International immunopharmacology 20031101

Cerebrovascular vasodilation to extraluminal acidosis occurs via combined activation of ATP-sensitive and Ca2+-activated potassium channels.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20031001

ATP-sensitive K+ channel openers: old drugs with new clinical benefits for the heart.

Current vascular pharmacology 20031001

Molecular basis and characteristics of KATP channel in human corporal smooth muscle cells.

International journal of impotence research 20030801

The NO-cGMP-K+ channel pathway participates in the antinociceptive effect of diclofenac, but not of indomethacin.

Pharmacology, biochemistry, and behavior 20030801

ATP-dependent potassium channels involved in the cardiac protection induced by intermittent hypoxia against ischemia/reperfusion injury.

Life sciences 20030725

Effect of high concentration of glucose on dopamine release from pheochromocytoma-12 cells.

Metabolism: clinical and experimental 20030701

ATP-sensitive potassium channels in rat primary afferent neurons: the effect of neuropathic injury and gabapentin.

Neuroscience letters 20030612

K-ATP channel independent effects of pinacidil on ATP production in isolated cardiomyocyte or pancreatic beta-cell mitochondria.

Biochemical pharmacology 20030601

NADH supplementation decreases pinacidil-primed I K ATP in ventricular cardiomyocytes by increasing intracellular ATP.

British journal of pharmacology 20030601

[Effect of pinacidil on rat myocardial calcium regulation].

Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20030601

SNC-80-induced preconditioning: selective activation of the mitochondrial adenosine triphosphate-gated potassium channel.

Journal of cardiovascular pharmacology 20030501

Myocardial protection of immature rabbits: polarizing versus depolarizing.

The Journal of surgical research 20030501

Potassium channel activators based on the benzopyran substructure: synthesis and activity of the C-8 substituent.

Bioorganic & medicinal chemistry 20030417

Modulation of slow waves by hyperpolarization with potassium channel openers in antral smooth muscle of the guinea-pig stomach.

The Journal of physiology 20030401

Adenine nucleotide translocase mediates the K(ATP)-channel-openers-induced proton and potassium flux to the mitochondrial matrix.

Journal of bioenergetics and biomembranes 20030401

Synthesis and biological activity of 3,3-diamino-sulfonylacrylonitriles as novel inhibitors of glucose induced insulin secretion from beta cells.

Bioorganic & medicinal chemistry 20030320

Effects of L-type Ca(2+)-channel blockade, K(+)(ATP)-channel opening and nitric oxide on human uterine contractility in relation to gestational age and labour.

Molecular human reproduction 20030301

Selective mitochondrial KATP channel activation by nicorandil and 3-pyridyl pinacidil results in antiarrhythmic effect in an anesthetized rabbit model of myocardial ischemia/reperfusion.

Methods and findings in experimental and clinical pharmacology 20030301

Modulation of the trafficking efficiency and functional properties of ATP-sensitive potassium channels through a single amino acid in the sulfonylurea receptor.

The Journal of biological chemistry 20030227

An endothelium-derived factor modulates purinergic neurotransmission to mesenteric arterial smooth muscle of hamster.

European journal of pharmacology 20030214

Contribution of Na+ -Ca2+ exchanger to pinacidil-induced relaxation in the rat mesenteric artery.

British journal of pharmacology 20030201

Isoflurane sensitizes the cardiac sarcolemmal adenosine triphosphate-sensitive potassium channel to pinacidil.

Anesthesiology 20030101

Gender differences in effects of pinacidil but not diazoxide on heart automatism in the isolated guinea pig right atria.

Polish journal of pharmacology 20030101

Pinacidil-induced opening, like glibenclamide-induced closure of cardiac KATP channels, protects cardiac function against ischemia in isolated, working, erythrocyte perfused rat hearts.

Advances in experimental medicine and biology 20030101

[Role of ATP-sensitive potassium channel activators in liver mitochondrial function in rats with different resistance to hypoxia].

Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20030101

Cardiomyocyte mitochondrial KATP channels participate in the antiarrhythmic and antiinfarct effects of KATP activators during ischemia and reperfusion in an intact anesthetized rabbit model.

Polish journal of pharmacology 20030101

[Effect of ATP-sensitive potassium channel modulators and intermittent hypoxia on mitochondrial respiration during stress].

Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20030101

Improved myocardial function with the addition of pinacidil to custadiol.

Transplantation 20021227

Smooth muscle membrane potential modulates endothelium-dependent relaxation of rat basilar artery via myo-endothelial gap junctions.

The Journal of physiology 20021215

Developmental expression and functional significance of Kir channel subunits in ureteric bud and nephron epithelia.

Pflugers Archiv : European journal of physiology 20021201

Properties of unitary potentials recorded from myenteric interstitial cells of Cajal distributed in the guinea-pig gastric antrum.

Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi 20021201

The stereoenantiomers of a pinacidil analog open or close cloned ATP-sensitive K+ channels.

The Journal of biological chemistry 20021025

Effect of diabetes on pinacidil-induced antinociception in mice.

European journal of pharmacology 20021025

Ionic and cellular basis for the predominance of the Brugada syndrome phenotype in males.

Circulation 20021008

Membrane potential controls calcium entry into descending vasa recta pericytes.

American journal of physiology. Regulatory, integrative and comparative physiology 20021001

Monolithic matrix type transdermal drug delivery systems of pinacidil monohydrate: in vitro characterisation.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20020901

Opening of ATP-sensitive potassium channels causes generation of free radicals in vascular smooth muscle cells.

Basic research in cardiology 20020901

Nitric oxide induces hyperpolarization by opening ATP-sensitive K(+) channels in guinea pig spiral modiolar artery.

Hearing research 20020901

Molecular basis of ATP-sensitive K+ channels in rat vascular smooth muscles.

Biochemical and biophysical research communications 20020816

Activation of adenosine triphosphate-sensitive potassium channels confers protection against rotenone-induced cell death: therapeutic implications for Parkinson's disease.

Journal of neuroscience research 20020815

Alpha1-adrenoceptor-mediated breakdown of phosphatidylinositol 4,5-bisphosphate inhibits pinacidil-activated ATP-sensitive K+ currents in rat ventricular myocytes.

Circulation research 20020809

Inhibitory effects of potassium channel blockers on tetramethylpyrazine-induced relaxation of rat aortic strip in vitro.

Life sciences 20020802

K(ATP) channel-independent targets of diazoxide and 5-hydroxydecanoate in the heart.

The Journal of physiology 20020801

The effects of drugs modulating K(+) transport on Rb(+) uptake and distribution in pig hearts following regional ischemia: (87)Rb MRI study.

NMR in biomedicine 20020801

The role of myocardial KATP-channel blockade in the protective effects of glibenclamide against ischaemia in the rat heart.

Pharmacology & toxicology 20020801

Potassium channels and human corporeal smooth muscle cell tone: diabetes and relaxation of human corpus cavernosum smooth muscle by adenosine triphosphate sensitive potassium channel openers.

The Journal of urology 20020701

Mitochondrial K(ATP) channel openers activate the ERK kinase by an oxidant-dependent mechanism.

American journal of physiology. Cell physiology 20020701

D2-like receptor-mediated inhibition of Na+-K+-ATPase activity is dependent on the opening of K+ channels.

American journal of physiology. Renal physiology 20020701

Ketamine abolishes ischemic preconditioning through inhibition of K(ATP) channels in rabbit hearts.

American journal of physiology. Heart and circulatory physiology 20020701

Hypoxic vasorelaxation inhibition by organ culture correlates with loss of Kv channels but not Ca(2+) channels.

American journal of physiology. Heart and circulatory physiology 20020701

Differential modulation of the cardiac adenosine triphosphate-sensitive potassium channel by isoflurane and halothane.

Anesthesiology 20020701

Effect of adenosine triphosphate-sensitive potassium channel openers on lung preservation.

American journal of respiratory and critical care medicine 20020601

Inhaled pinacidil, an ATP-sensitive K+ channel opener, and moguisteine have potent antitussive effects in guinea pigs.

Japanese journal of pharmacology 20020601

[New medications for treatment of erectile dysfunction].

Nihon rinsho. Japanese journal of clinical medicine 20020601

Vasorelaxing properties of some phenylacridine type potassium channel openers in isolated rabbit thoracic arteries.

European journal of medicinal chemistry 20020601

Effect of 17beta-estradiol exposure on vasorelaxation induced by K(+) channel openers and Ca(2+) channel blockers.

Pharmacology 20020501

Opening of mitochondrial ATP-sensitive potassium channels evokes oxygen radical generation in rabbit heart slices.

Journal of biochemistry 20020501

Effects of K(ATP) channel modulators on acetylcholine release from guinea-pig isolated atria and small intestine.

Naunyn-Schmiedeberg's archives of pharmacology 20020501

Isoflurane inhibits neutrophil-endothelium interactions in the coronary circulation: lack of a role for adenosine triphosphate-sensitive potassium channels.

Anesthesia and analgesia 20020401

Effects of K(ATP) channel openers, P-1075, pinacidil, and diazoxide, on energetics and contractile function in isolated rat hearts.

Journal of molecular and cellular cardiology 20020401

Nicorandil inhibits degranulation and TNF-alpha release from RBL-2H3 cells.

Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20020401

Characterisation of the effects of potassium channel modulating agents on mouse intestinal smooth muscle.

The Journal of pharmacy and pharmacology 20020301

Pharmacological evidence for the activation of K(+) channels by diclofenac.

European journal of pharmacology 20020301

Cytochrome P450 3A4-mediated oxidative conversion of a cyano to an amide group in the metabolism of pinacidil.

Biochemistry 20020226

Interactions of sildenafil with various coronary vasodilators in isolated porcine coronary artery.

European journal of pharmacology 20020222

Diazoxide and pinacidil uncouple pyruvate-malate-induced mitochondrial respiration.

Journal of bioenergetics and biomembranes 20020201

ATP-sensitive K(+) channels composed of Kir6.1 and SUR2B subunits in guinea pig gastric myocytes.

American journal of physiology. Gastrointestinal and liver physiology 20020101

Myocardial protection with pinacidil induced hyperpolarized arrest during cardiopulmonary bypass.

Chinese medical journal 20011201

Myocardial protection of immature rabbits with an ATP-sensitive K+ channel opener pinacidil.

Chinese medical journal 20011101

Dimethylsulfoxide and ethanol, commonly used diluents, prevent dilation of pial arterioles by openers of K(ATP) ion channels.

European journal of pharmacology 20011026

Regulation of ATP-sensitive K(+) channels by protein kinase C in murine colonic myocytes.

American journal of physiology. Cell physiology 20010901

Contribution of both the sarcolemmal K(ATP) and mitochondrial K(ATP) channels to infarct size limitation by K(ATP) channel openers: differences from preconditioning in the role of sarcolemmal K(ATP) channels.

Naunyn-Schmiedeberg's archives of pharmacology 20010901

Gender-specific difference in cardiac ATP-sensitive K(+) channels.

Journal of the American College of Cardiology 20010901

Antisense knockdown of inducible nitric oxide synthase inhibits the relaxant effect of VIP in isolated smooth muscle cells of the mouse gastric fundus.

British journal of pharmacology 20010901

Sulfonylurea receptors inhibit the epithelial sodium channel (ENaC) by reducing surface expression.

Pflugers Archiv : European journal of physiology 20010801

Comparison of the inhibitory effects of cromakalim and pinacidil (potassium channel openers) with those of oxybutynin on stimulated guinea pig and rabbit detrusor muscle strips.

Archives of gynecology and obstetrics 20010801

Influence of ATP-sensitive K+ channel modulation on the mechanical properties of diabetic myocardium.

Endocrine research 20010801

Adenosine activates ATP-sensitive K(+) currents in pericytes of rat retinal microvessels: role of A1 and A2a receptors.

Brain research 20010713

Denervation enhances the physiological effects of the K(ATP) channel during fatigue in EDL and soleus muscle.

American journal of physiology. Regulatory, integrative and comparative physiology 20010701

Mitochondrial ATP-sensitive potassium channels inhibit apoptosis induced by oxidative stress in cardiac cells.

Circulation research 20010622

Pinacidil prevents membrane depolarisation and intracellular Ca2+ loading in single cardiomyocytes exposed to severe metabolic stress.

International journal of molecular medicine 20010601

K(ATP) channel currents regulate membrane potential in freshly isolated human and rat bladder smooth muscle cells.

Urology 20010601

Changes in electrical properties of detrusor smooth muscle in the STZ (streptozotocin)-diabetic rat.

Urology 20010601

Modulation of K+-evoked [3H]-noradrenaline release from rat and human brain slices by gabapentin: involvement of KATP channels.

Naunyn-Schmiedeberg's archives of pharmacology 20010501

Vasorelaxing effect of the potassium (K+)-channel opener pinacidil in isolated porcine ciliary arteries.

Klinische Monatsblatter fur Augenheilkunde 20010501

Delivery of genes encoding cardiac K(ATP) channel subunits in conjunction with pinacidil prevents membrane depolarization in cells exposed to chemical hypoxia-reoxygenation.

Biochemical and biophysical research communications 20010420

Evidence for a K(ATP) ion channel link in the inhibition of hypercapnic dilation of pial arterioles by 7-nitroindazole and tetrodotoxin.

European journal of pharmacology 20010413

ATP consumption by uncoupled mitochondria activates sarcolemmal K(ATP) channels in cardiac myocytes.

American journal of physiology. Heart and circulatory physiology 20010401

Levosimendan increases diastolic coronary flow in isolated guinea-pig heart by opening ATP-sensitive potassium channels.

Journal of cardiovascular pharmacology 20010401

Relaxant effects of 17-beta-estradiol in cerebral arteries through Ca(2+) entry inhibition.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20010401

Functional roles of cardiac and vascular ATP-sensitive potassium channels clarified by Kir6.2-knockout mice.

Circulation research 20010330

Functional implication of spare ATP-sensitive K(+) channels in bladder smooth muscle cells.

The Journal of pharmacology and experimental therapeutics 20010301

ATP-sensitive K+ channels and cytoprotection.

Developmental medicine and child neurology. Supplement 20010301

Activation of Na(+), K(+), Cl(-)-cotransport mediates intracellular Ca(2+) increase and apoptosis induced by Pinacidil in HepG2 human hepatoblastoma cells.

Biochemical and biophysical research communications 20010223

Bioenergetic consequences of opening the ATP-sensitive K(+) channel of heart mitochondria.

American journal of physiology. Heart and circulatory physiology 20010201

Pharmacological comparison of native mitochondrial K(ATP) channels with molecularly defined surface K(ATP) channels.

Molecular pharmacology 20010201

Altered effects of potassium channel modulation in the coronary circulation in experimental hypercholesterolemia.

Atherosclerosis 20010201

Effects of K+ channel openers on I K(ATP) of human atrial myocytes at physiological temperatures.

Naunyn-Schmiedeberg's archives of pharmacology 20010201

Role of potassium channels in regulation of brain arteriolar tone: comparison of cerebrum versus brain stem.

Stroke 20010101

A simple method to investigate the inhibitory effects of drugs on gastric emptying in the mouse in vivo.

Journal of pharmacological and toxicological methods 20010101

Fluorescence-based functional assay for sarcolemmal ATP-sensitive potassium channel activation in cultured neonatal rat ventricular myocytes.

Journal of pharmacological and toxicological methods 20010101

Hypotensive interaction of sildenafil and nicorandil in rats through the cGMP pathway but not by K(ATP) channel activation.

Japanese journal of pharmacology 20001101

A KATP-channel opener as a potential treatment modality for erectile dysfunction.

BJU international 19990501

Sulphonylurea receptor 2B and Kir6.1 form a sulphonylurea-sensitive but ATP-insensitive K+ channel.

The Journal of physiology 19970315

ATP-sensitive K+ channel opener pinacidil augments beta 1-adrenoceptor-induced coronary vasodilation in dogs.

The American journal of physiology 19960601

K+ channel openers delay intestinal transit and have antidiarrheal activity.

European journal of pharmacology 19951212

Pinacidil relaxes porcine and human coronary arteries by activating ATP-dependent potassium channels in smooth muscle cells.

The Journal of pharmacology and experimental therapeutics 19951101

Effect of four potassium channel agonists on bupivacaine-induced toxicity in mice.

Life sciences 19950101

Pinacidil-induced relaxation in pulmonary arteries isolated from pulmonary hypertensive and normotensive rats and pre-contracted with different spasmogens.

Pulmonary pharmacology 19941201

Selective in vivo antagonism of pinacidil-induced hypotension by the guanidine U37883A in anesthetized rats.

Pharmacology 19941201

Effects of pinacidil on guinea-pig isolated perfused heart with particular reference to the proarrhythmic effect.

British journal of pharmacology 19920301

Effects of cromakalim and pinacidil on large epicardial and small coronary arteries in conscious dogs.

The Journal of pharmacology and experimental therapeutics 19901101

Suppression of repolarization-related arrhythmias in vitro and in vivo by low-dose potassium channel activators.

Circulation 19901001

The initial hemodynamic response to newer antihypertensive agents at rest and during exercise: review of visacor, doxazosin, nisoldipine, tiapamil, perindoprilat, pinacidil, dilevalol, and carvedilol.

Cardiovascular drugs and therapy 19900801

Pinacidil. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in the treatment of hypertension.

Drugs 19900601

Effects of pinacidil and cromakalim (BRL 34915) on bladder function in rats with detrusor instability.

The Journal of urology 19891001

Comparative effects of nitroprusside and pinacidil on myocardial blood flow and infarct size in awake dogs with acute myocardial infarction.

Circulation 19880301

Acute hemodynamic effects of pinacidil and hydralazine in essential hypertension.

Clinical pharmacology and therapeutics 19850301

Suppression of ventricular arrhythmias after coronary artery ligation by pinacidil, a vasodilator drug.

Journal of cardiovascular pharmacology 19850101

Systemic and coronary hemodynamic effects of pinacidil in awake normotensive and hypertensive dogs.

Hypertension (Dallas, Tex. : 1979) 19850101

Vascular effects in dogs of pinacidil (P 1134), a novel vasoactive antihypertensive agent.

European journal of pharmacology 19830408