Neurokinin A
Title | Journal |
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The tachykinin peptide neurokinin B binds copper(I) and silver(I) and undergoes quasi-reversible electrochemistry: towards a new function for the peptide in the brain. | Neurochemistry international 20140501 |
In vitro pharmacological evaluation of the radiolabeled C-terminal substance P analogue Lys-Phe-Phe-Gly-Leu-Met-NH2: Does a specific binding site exist? | Folia neuropathologica 20140101 |
Copper(II) complexes of neurokinin A with point mutation (S5A) and products of copper-catalyzed oxidation; role of serine residue in peptides containing neurokinin A sequence. | Journal of inorganic biochemistry 20130401 |
Acid-base properties of the (1-4,18-36) fragments of neuropeptide K and their mono- and polynuclear copper(II) complexes products of metal-catalyzed oxidation. | Inorganic chemistry 20130107 |
Neurokinin2-R in medial septum regulate hippocampal and amygdalar ACh release induced by intraseptal application of neurokinins A and B. | Hippocampus 20120501 |
Involvement of midbrain tectum neurokinin-mediated mechanisms in fear and anxiety. | Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20120401 |
Tachykinins stimulate a subset of mouse taste cells. | PloS one 20120101 |
Substance P induces adverse myocardial remodelling via a mechanism involving cardiac mast cells. | Cardiovascular research 20111201 |
Substance P inhibits pancreatic ductal bicarbonate secretion via neurokinin receptors 2 and 3 in the guinea pig exocrine pancreas. | Pancreas 20110701 |
Novel expression of a functional glycine receptor chloride channel that attenuates contraction in airway smooth muscle. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20110501 |
Melatonin inhibits tachykinin NK₂ receptor-triggered 5-HT release from guinea pig isolated colonic mucosa. | British journal of pharmacology 20110301 |
Anti-inflammatory properties of montelukast, a leukotriene receptor antagonist in patients with asthma and nasal polyposis. | Journal of investigational allergology & clinical immunology 20110101 |
Tachykinin receptors antagonism for asthma: a systematic review. | BMC pulmonary medicine 20110101 |
Suppressive effects of glycyrrhetinic acid derivatives on tachykinin receptor activation and hyperalgesia. | Journal of pharmacological sciences 20110101 |
The possible link between the elevated serum levels of neurokinin A and anti-ribosomal P protein antibodies in children with autism. | Journal of neuroinflammation 20110101 |
Secretoneurin and the tachykinins substance P and neurokinin-A/B in NMDA-induced excitotoxicity in the rat retina. | Regulatory peptides 20101130 |
Modulation of the CRH system by substance P/NKA in an animal model of depression. | Behavioural brain research 20101112 |
Depression of cough reflex by microinjections of antitussive agents into caudal ventral respiratory group of the rabbit. | Journal of applied physiology (Bethesda, Md. : 1985) 20101001 |
Coordination abilities of neurokinin A and its derivative and products of metal-catalyzed oxidation. | Journal of inorganic biochemistry 20100801 |
Increased morphine analgesia and reduced side effects in mice lacking the tac1 gene. | British journal of pharmacology 20100701 |
Proteinase-activated receptor-2 activation evokes oesophageal longitudinal smooth muscle contraction via a capsaicin-sensitive and neurokinin-2 receptor-dependent pathway. | Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20100201 |
Central administration of substance P inhibits feeding behavior in chicks. | Hormones and behavior 20100201 |
Neurokinin-2 receptor antagonism in medial septum influences temporal-order memory for objects and forebrain cholinergic activity. | Peptides 20100101 |
Acute morphine effects on respiratory activity in mice with target deletion of the tachykinin 1 gene (Tac1-/-). | Advances in experimental medicine and biology 20100101 |
Effect of fluticasone on neuropeptides in nasal lavage in persistent allergic rhinitis. | Journal of investigational allergology & clinical immunology 20100101 |
Multidrug resistance protein transporter and Ins(1,4,5)P₃-sensitive Ca²+-signaling involved in adenosine triphosphate export via Gq protein-coupled NK₂-receptor stimulation with neurokinin A. | Journal of pharmacological sciences 20100101 |
Autocrine regulation of human sperm motility by tachykinins. | Reproductive biology and endocrinology : RB&E 20100101 |
Localization of TRPV1 and contractile effect of capsaicin in mouse large intestine: high abundance and sensitivity in rectum and distal colon. | American journal of physiology. Gastrointestinal and liver physiology 20090801 |
Morphine-induced early delays in wound closure: involvement of sensory neuropeptides and modification of neurokinin receptor expression. | Biochemical pharmacology 20090601 |
Involvement of NMDA receptor in nociceptive effects elicited by intrathecal [Tyr6] gamma2-MSH(6-12), and the interaction with nociceptin/orphanin FQ in pain modulation in mice. | Brain research 20090519 |
Cyclooxygenase-dependent alterations in substance P-mediated contractility and tachykinin NK1 receptor expression in the colonic circular muscle of patients with slow transit constipation. | The Journal of pharmacology and experimental therapeutics 20090401 |
An extract (THC-002) of Ba-Wei-Die-Huang-Wan inhibits expression of tachykinins, and P2X3 and TRPV1 receptors, and inhibits ATP-induced detrusor overactivity in spontaneously hypertensive rats. | Neurourology and urodynamics 20090101 |
NK1 receptor-mediated endothelium-dependent relaxation and contraction with different sensitivity to post-receptor signaling in pulmonary arteries. | Vascular pharmacology 20090101 |
Activation of endogenous GABAA channels on airway smooth muscle potentiates isoproterenol-mediated relaxation. | American journal of physiology. Lung cellular and molecular physiology 20081201 |
Neurokinin-A inhibits cell cycle activators in K562 cells and activates Smad 4 through a non-canonical pathway: a novel method in neural-hematopoietic axis. | Journal of neuroimmunology 20081115 |
Modulation of the cough reflex by antitussive agents within the caudal aspect of the nucleus tractus solitarii in the rabbit. | American journal of physiology. Regulatory, integrative and comparative physiology 20080701 |
Neurokinin receptor modulation of respiratory activity in the rabbit. | The European journal of neuroscience 20080601 |
Neurokinin 2 receptor-mediated activation of protein kinase C modulates capsaicin responses in DRG neurons from adult rats. | The European journal of neuroscience 20080601 |
Novel triple neurokinin receptor antagonist CS-003 strongly inhibits neurokinin related responses. | European journal of pharmacology 20080531 |
Estrogen determines sex differences in airway responsiveness after allergen exposure. | American journal of respiratory cell and molecular biology 20080501 |
Contractile properties of the pig bladder mucosa in response to neurokinin A: a role for myofibroblasts? | British journal of pharmacology 20080401 |
Changes in the control of gastric motor activity during metamorphosis in the amphibian Xenopus laevis, with special emphasis on purinergic mechanisms. | The Journal of experimental biology 20080401 |
Expression and coupling of neurokinin receptor subtypes to inositol phosphate and calcium signaling pathways in human airway smooth muscle cells. | American journal of physiology. Lung cellular and molecular physiology 20080301 |
Chronic inflammation alters the contribution of neurokinin receptor subtypes to epithelial function in rat colon. | Digestive diseases and sciences 20080101 |
The effect of the leukotriene receptor antagonist zafirlukast on neurokinin A-induced bronchoconstriction in patients with asthma--A comparison with leukotriene D4 induced broncoconstriction. | Pulmonary pharmacology & therapeutics 20080101 |
Capsaicin-sensitive nerves and neurokinins modulate non-neuronal nNOS expression in lung. | Respiratory physiology & neurobiology 20080101 |
Tachykinin NK2 receptor and functional mechanisms in human colon: changes with indomethacin and in diverticular disease and ulcerative colitis. | The Journal of pharmacology and experimental therapeutics 20080101 |
Nerve growth factor enhances neurokinin A-induced airway responses and exhaled nitric oxide via a histamine-dependent mechanism. | Pulmonary pharmacology & therapeutics 20080101 |
Gosha-jinki-gan reduces transmitter proteins and sensory receptors associated with C fiber activation induced by acetic acid in rat urinary bladder. | Neurourology and urodynamics 20080101 |
Contractile effect of tachykinins on Suncus murinus (house musk shrew) isolated ileum. | Neuropeptides 20080101 |
Senktide-induced gerbil foot tapping behaviour is blocked by selective tachykinin NK1 and NK3 receptor antagonists. | European journal of pharmacology 20071222 |
Effect of melatonin on the vasopressin secretion as influenced by tachykinin NK-1 receptor agonist and antagonist: in vivo and in vitro studies. | Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20071201 |
Fluorometric immunoassay based on pH-sensitive dye-encapsulating liposomes and gramicidin channels. | Analytical biochemistry 20071015 |
Intraluminal acid induces oesophageal shortening via capsaicin-sensitive neurokinin neurons. | Gut 20071001 |
Distribution of neuroendocrine cells in the small and large intestines of the one-humped camel (Camelus dromedarius). | Neuropeptides 20071001 |
Role for NK(1) and NK(2) receptors in the motor activity in mouse colon. | European journal of pharmacology 20070910 |
Pelviureteric peristaltic contractions in diabetic rats. | Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi 20070801 |
A novel, conformation-specific allosteric inhibitor of the tachykinin NK2 receptor (NK2R) with functionally selective properties. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20070701 |
A role for tachykinins in the regulation of human sperm motility. | Human reproduction (Oxford, England) 20070601 |
Role of MUC5AC in the pathogenesis of exercise-induced bronchoconstriction. | The Journal of allergy and clinical immunology 20070501 |
Neurokinins enhance excitability in capsaicin-responsive DRG neurons. | Experimental neurology 20070501 |
Intrathecally administered D-cycloserine produces nociceptive behavior through the activation of N-methyl-D-aspartate receptor ion-channel complex acting on the glycine recognition site. | Journal of pharmacological sciences 20070501 |
The effects of saltwater acclimation on neurotransmitters in the lingual salt glands of the estuarine crocodile, Crocodylus porosus. | Regulatory peptides 20070405 |
Distribution of neurokinin A-like and serotonin immunoreactivities within the vertical lobe complex in Sepia officinalis. | Brain research 20070216 |
Thiorphan, a neutral endopeptidase inhibitor used for diarrhoea, is neuroprotective in newborn mice. | Brain : a journal of neurology 20061201 |
MEN15596, a novel nonpeptide tachykinin NK2 receptor antagonist. | European journal of pharmacology 20061107 |
Circulating markers of prognosis and response to treatment in patients with midgut carcinoid tumours. | Gut 20061101 |
Ontogeny of excitatory and inhibitory control of gastrointestinal motility in the African clawed frog, Xenopus laevis. | American journal of physiology. Regulatory, integrative and comparative physiology 20061001 |
Neurokinin3 receptor regulation of the airways. | Vascular pharmacology 20061001 |
Regulation of the stimulant actions of neurokinin a and human hemokinin-1 on the human uterus: a comparison with histamine. | Biology of reproduction 20060901 |
The inhibitory effects of local anesthetics on primary sensory nerve and parasympathetic nerve in rabbit eye. | Anesthesia and analgesia 20060901 |
Contribution of Rho-kinase in human gallbladder contractions. | European journal of pharmacology 20060701 |
Beclomethasone dipropionate attenuates airways hyperresponsiveness to neurokinin A and histamine in asthma. | Respiratory medicine 20060601 |
NK2 receptor-mediated spontaneous phasic contractions in normal and ulcerative colitis human sigmoid colon. | The Journal of pharmacology and experimental therapeutics 20060601 |
Nongenomic effects of progesterone on the contraction of muscle cells from the guinea pig colon. | American journal of physiology. Gastrointestinal and liver physiology 20060501 |
Substance P initiates NFAT-dependent gene expression in spinal neurons. | Journal of neurochemistry 20060401 |
Depressed contractile responses to neurokinin A in idiopathic but not neurogenic overactive human detrusor muscle. | European urology 20060301 |
Clinical-biochemical correlates of migraine attacks in rizatriptan responders and non-responders. | Cephalalgia : an international journal of headache 20060301 |
Role of NK1 and NK2 receptors in mouse gastric mechanical activity. | British journal of pharmacology 20060201 |
Rho kinase expression and its central role in ovine gallbladder contractions elicited by a variety of excitatory stimuli. | European journal of pharmacology 20051228 |
Production of IL-1beta, hydrogen peroxide, and nitric oxide by colonic mucosa decreases sigmoid smooth muscle contractility in ulcerative colitis. | American journal of physiology. Cell physiology 20051201 |
Substance P, neurokinins A and B, and synthetic tachykinin peptides protect mesencephalic dopaminergic neurons in culture via an activity-dependent mechanism. | Molecular pharmacology 20051101 |
Endobronchial adenosine monophosphate challenge causes tachykinin release in the human airway. | The Journal of allergy and clinical immunology 20050801 |
The ventral tegmental area as a putative target for tachykinins in cardiovascular regulation. | British journal of pharmacology 20050701 |
The Kell protein of the common K2 phenotype is a catalytically active metalloprotease, whereas the rare Kell K1 antigen is inactive. Identification of novel substrates for the Kell protein. | The Journal of biological chemistry 20050603 |
Pharmacology of an original and selective nonpeptide antagonist ligand for the human tachykinin NK2 receptor. | European journal of pharmacology 20050601 |
Effect of social isolation on ethanol consumption and substance P/neurokinin expression in Wistar rats. | Alcohol (Fayetteville, N.Y.) 20050601 |
Impaired capsaicin and neurokinin-evoked colonic motility in inflammatory bowel disease. | Journal of gastroenterology and hepatology 20050501 |
Tachykinins and tachykinin-receptors in the rat pineal gland. | The European journal of neuroscience 20050501 |
Neurokinins and inflammatory cell iNOS expression in guinea pigs with chronic allergic airway inflammation. | American journal of physiology. Lung cellular and molecular physiology 20050401 |
Pharmacological investigation of hydrogen sulfide (H2S) contractile activity in rat detrusor muscle. | European journal of pharmacology 20050221 |
Neurokinin a is a main constituent of sensory neurons innervating the anterior segment of the eye. | Investigative ophthalmology & visual science 20050101 |
GABA(A) receptor facilitation of neurokinin release from primary afferent terminals in the rat spinal cord. | Neuroscience 20050101 |
Relationship between airway responsiveness to neurokinin A and methacholine in asthma. | Pulmonary pharmacology & therapeutics 20050101 |
Tachykinin neuropeptides in cerebellar granule neurons: an immunocytochemical study. | European journal of histochemistry : EJH 20050101 |
Involvement of Ca2+ signaling in tachykinin-mediated contractile responses in swine trachea. | Journal of biomedical science 20050101 |
[Effect of natural tachykinins on the bile production in rats]. | Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20050101 |
[Structure-function organization of neurokinin A and neurokinin B molecules. III. A conformational study of glycine-monosubstituted analogues of neurokinins A and B]. | Biofizika 20050101 |
Cannabinoid receptor agonists inhibit sensory nerve activation in guinea pig airways. | American journal of respiratory and critical care medicine 20041101 |
Ontogeny of the gut motility control system in zebrafish Danio rerio embryos and larvae. | The Journal of experimental biology 20041101 |
Interleukin 1beta-induced production of H2O2 contributes to reduced sigmoid colonic circular smooth muscle contractility in ulcerative colitis. | The Journal of pharmacology and experimental therapeutics 20041001 |
Pharmacological evaluation of alpha and beta human tachykinin NK(2) receptor splice variants expressed in CHO cells. | European journal of pharmacology 20040924 |
Mechanisms of neurokinin A- and substance P-induced contractions in rat detrusor smooth muscle in vitro. | BJU international 20040901 |
Greater involvement of neurokinins found in Guinea pig models of severe asthma compared with mild asthma. | International archives of allergy and immunology 20040801 |
Functional role of the Na+/H+ exchanger in the regulation of cerebral arteriolar tone in rats. | Journal of neurosurgery 20040801 |
Influence of maturation on constrictive response to stimulation of C-fiber afferents in isolated guinea pig airways. | American journal of physiology. Lung cellular and molecular physiology 20040701 |
Pharmacologic evaluation of neurokinin-2 receptor antagonists in the guinea pig respiratory tract. | American journal of veterinary research 20040701 |
Seasonal changes of SP and NKA in frontal cortex, striatum and testes in the rat. Role of maternal pineal gland. | Peptides 20040601 |
Hydrogen peroxide contributes to motor dysfunction in ulcerative colitis. | American journal of physiology. Gastrointestinal and liver physiology 20040501 |
Pemirolast potently attenuates paclitaxel hypersensitivity reactions through inhibition of the release of sensory neuropeptides in rats. | Neuropharmacology 20040501 |
Effects of TAK-637 on NK(1) receptor-mediated mechanisms regulating colonic secretion. | Toxicology and applied pharmacology 20040415 |
Leukocyte recruitment to peritoneal cavity of rats following formalin injection: role of tachykinin receptors. | Journal of pharmacological sciences 20040401 |
Effects of neuropeptides on the sumatriptan-disturbed circulation in the optic nerve head of rabbits. | Pharmacology 20040301 |
Role of neuropeptide receptor systems in vanilloid VR1 receptor-mediated gastric acid secretion in rat brain. | European journal of pharmacology 20040223 |
Neurokinin peptides and neurokinin receptors as potential therapeutic intervention targets of basal ganglia in the prevention and treatment of Parkinson's disease. | Current drug targets 20040201 |
Role of sensory nerve peptides rather than mast cell histamine in paclitaxel hypersensitivity. | American journal of respiratory and critical care medicine 20040101 |
Dual tachykinin NK1/NK2 antagonist DNK333 inhibits neurokinin A-induced bronchoconstriction in asthma patients. | The European respiratory journal 20040101 |
Neurokinin-1 receptors in the rat nucleus tractus solitarius: pre- and postsynaptic modulation of glutamate and GABA release. | Neuroscience 20040101 |
Effect of peptidases on the ability of exogenous and endogenous neurokinins to produce neurokinin 1 receptor internalization in the rat spinal cord. | British journal of pharmacology 20031201 |
Three-dimensional structure of the mammalian tachykinin peptide neurokinin A bound to lipid micelles. | Biophysical journal 20031201 |
Cholinergic transmission to colonic circular muscle of children with slow-transit constipation is unimpaired, but transmission via NK2 receptors is lacking. | Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20031201 |
Similarities of SP-, NKA- and NKB-induced currents in rat dorsal root ganglion neurons. | Brain research 20031121 |
Inhibition of human detrusor contraction by a urothelium derived factor. | The Journal of urology 20031101 |
Investigation of neurokinin-2 and -3 receptors in the human and pig bladder. | BJU international 20031101 |
PAR-2 agonists induce contraction of murine small intestine through neurokinin receptors. | American journal of physiology. Gastrointestinal and liver physiology 20031001 |
Characterization of tachykinin NK2 receptor in the anterior pituitary gland. | Life sciences 20030926 |
A role for tachykinins in female mouse and rat reproductive function. | Biology of reproduction 20030901 |
Human tachykinin NK2 receptor: a comparative study of the colon and urinary bladder. | Clinical and experimental pharmacology & physiology 20030901 |
Tachykinins mediate non-adrenergic, non-cholinergic excitatory neurotransmission to the hamster ileum via NK1 and NK2 receptors. | Life sciences 20030829 |
Miniaturization of fluorescence polarization receptor-binding assays using CyDye-labeled ligands. | Journal of biomolecular screening 20030801 |
[Effect of substance K on the contractility of cardiomyocytes]. | Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20030801 |
Tachykinin receptor (NK(1), NK(2), NK(3)) binding sites in the rat caudal brainstem following neonatal capsaicin administration. | Brain research 20030725 |
Action of tachykinins in the rat hippocampus: modulation of inhibitory synaptic transmission. | The European journal of neuroscience 20030601 |
Pharmacological properties of peptides derived from an antibody against the tachykinin NK1 receptor for the neuropeptide substance P. | European journal of pharmacology 20030516 |
Bone marrow transplantation reveals an essential synergy between neuronal and hemopoietic cell neurokinin production in pulmonary inflammation. | The Journal of clinical investigation 20030401 |
Inhibitory effect of a leukotriene receptor antagonist (montelukast) on neurokinin A-induced bronchoconstriction. | The Journal of allergy and clinical immunology 20030401 |
Substance P modulates localized calcium transients and membrane current responses in murine colonic myocytes. | British journal of pharmacology 20030401 |
Biologic activity of the tachykinins on lamb and sheep gallbladder. | Peptides 20030401 |
Intrathecal histamine induces spinally mediated behavioral responses through tachykinin NK1 receptors. | Pharmacology, biochemistry, and behavior 20030101 |
A tachykinin-like factor increases glutamate toxicity in rat cerebellar granule cells. | Neuropharmacology 20030101 |
Mapping of neurokinin-like immunoreactivity in the human brainstem. | BMC neuroscience 20030101 |
Effects of neurokinins on airway and alveolar eosinophil recruitment. | Experimental lung research 20030101 |
SR 142801, a tachykinin NK(3) receptor antagonist, prevents beta(2)-adrenoceptor agonist-induced hyperresponsiveness to neurokinin A in guinea-pig isolated trachea. | Life sciences 20021206 |
Interactions of volatile anesthetics with cholinergic, tachykinin, and leukotriene mechanisms in isolated Guinea pig bronchial smooth muscle. | Anesthesia and analgesia 20021201 |
Neurokinin A and the neurohypophysial response to melatonin: in vitro studies. | Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20021201 |
Mutations in the extracellular amino-terminal domain of the NK2 neurokinin receptor abolish cAMP signaling but preserve intracellular calcium responses. | The Journal of biological chemistry 20021101 |
The mechanisms for tachykinin-induced contractions of the rabbit corpus cavernosum. | British journal of pharmacology 20021101 |
Neurokinin-receptor-mediated depolarization of cortical neurons elicits an increase in glutamate release at excitatory synapses. | The European journal of neuroscience 20021101 |
The primary structures and myotropic activities of two tachykinins isolated from the African clawed frog, Xenopus laevis. | Regulatory peptides 20021015 |
Intrathecally administered big dynorphin, a prodynorphin-derived peptide, produces nociceptive behavior through an N-methyl-D-aspartate receptor mechanism. | Brain research 20021011 |
Roles of substance P receptors in human colon circular muscle: alterations in diverticular disease. | The Journal of pharmacology and experimental therapeutics 20020801 |
Tachykinin-independent activity of capsaicin on in-vitro lamb detrusor. | The Journal of pharmacy and pharmacology 20020801 |
Non-adrenergic non-cholinergic excitatory innervation in the airways: role of neurokinin-2 receptors. | Autonomic & autacoid pharmacology 20020801 |
Effect of monensin on the levels of tachykinins and their processing enzyme activity in rat dorsal root ganglia. | Neuroscience letters 20020628 |
Effect of inhaled fluticasone on bronchial responsiveness to neurokinin A in asthma. | The European respiratory journal 20020601 |
Effect of YM-44781, YM-44778 and YM-49598, novel tachykinin antagonists, in a drug-induced bladder contraction model. | Pharmacology 20020501 |
Age differences in neurokinin A and substance P from the hypothalamus, pituitary, pineal gland, and striatum of the rat. Effect of exogenous melatonin. | Peptides 20020501 |
Tachykinin-stimulated small bowel myoelectric pattern: sensitization by NO inhibition, reversal by neurokinin receptor blockade. | Regulatory peptides 20020415 |
Abnormal motility in patients with ulcerative colitis: the role of inflammatory cytokines. | Archives of surgery (Chicago, Ill. : 1960) 20020401 |
Effect of tachykinins on ascending and descending reflex pathway in rat small intestine. | Acta pharmacologica Sinica 20020401 |
Role of tachykinins in sephadex-induced airway hyperreactivity and inflammation in guinea pigs. | European journal of pharmacology 20020329 |
Enhancement of neurokinin A-induced smooth muscle contraction in human urinary bladder by mucosal removal and phosphoramidon: relationship to peptidase inhibition. | European journal of pharmacology 20020308 |
Cyclo-oxygenase- and capsaicin-sensitive afferent fibres affect Beta-adrenoceptor-evoked response in the rat urinary bladder. | Pharmacology 20020201 |
Nonpeptide tachykinin receptor antagonists. III. SB 235375, a low central nervous system-penetrant, potent and selective neurokinin-3 receptor antagonist, inhibits citric acid-induced cough and airways hyper-reactivity in guinea pigs. | The Journal of pharmacology and experimental therapeutics 20020101 |
Pharmacological profile of the novel mammalian tachykinin, hemokinin 1. | British journal of pharmacology 20020101 |
In vivo metabolism and clearance of substance P and co-expressed tachykinins in rat striatum. | Neuroscience 20020101 |
Role of cholinergic reflexes on the bronchoconstrictor reactivity to neurokinin a in allergic dogs. | Pulmonary pharmacology & therapeutics 20020101 |
Activation of neurokinin-1 receptors promotes GABA release at synapses in the rat entorhinal cortex. | Neuroscience 20020101 |
Neurokinin release in the rat nucleus of the solitary tract via NMDA and AMPA receptors. | Neuroscience 20020101 |
2-Aryl indole NK(1) antagonists: optimisation of the amide substituent. | Bioorganic & medicinal chemistry letters 20011203 |
Endothelin-1 increases cholinergic nerve-mediated contraction of human bronchi via tachykinin synthesis induction. | British journal of pharmacology 20011201 |
Presence of NK2 binding sites in the rat brain. | Journal of neurochemistry 20011201 |
Effect of neutral endopeptidase inhibitor on bradykinin-induced bronchoconstriction. | Life sciences 20011121 |
Impaired response to chemical irritation of the urinary tract in mice with disruption of the preprotachykinin gene. | Neuroscience letters 20011102 |
The neurosensory tachykinins substance P and neurokinin A directly induce keratinocyte nerve growth factor. | The Journal of investigative dermatology 20011101 |
Sources of calcium in neurokinin A-induced contractions of human colonic smooth muscle in vitro. | The American journal of gastroenterology 20011101 |
Substance P and neurokinin levels are decreased in the cortex and hypothalamus of alcohol-preferring (P) rats. | Journal of studies on alcohol 20011101 |
Interaction of Met297 in the seventh transmembrane segment of the tachykinin NK2 receptor with neurokinin A. | The Journal of biological chemistry 20011012 |
Pronociceptive effects of nociceptin/orphanin FQ (13-17) at peripheral and spinal level in mice. | The Journal of pharmacology and experimental therapeutics 20011001 |
Nepadutant pharmacokinetics and dose-effect relationships as tachykinin NK2 receptor antagonist are altered by intestinal inflammation in rodent models. | The Journal of pharmacology and experimental therapeutics 20011001 |
Radioligand binding and functional characterisation of tachykinin receptors in chicken small intestine. | Naunyn-Schmiedeberg's archives of pharmacology 20011001 |
Progesterone and norethisterone have different effects on tachykinin-like immunoreactivity in rat cortex and striatum. | Regulatory peptides 20010915 |
The neurokinin A receptor activates calcium and cAMP responses through distinct conformational states. | The Journal of biological chemistry 20010914 |
The role of sensory neuropeptides in motor innervation of the hamster isolated urinary bladder. | Naunyn-Schmiedeberg's archives of pharmacology 20010901 |
Effects of TAK-637, a novel neurokinin-1 receptor antagonist, on colonic function in vivo. | The Journal of pharmacology and experimental therapeutics 20010801 |
Tachykinin NK(2) receptors and enhancement of cholinergic transmission in the inflamed rat colon: an in vivo motility study. | British journal of pharmacology 20010801 |
Human colonic anti-secretory activity of the potent NK(1) antagonist, SR140333: assessment of potential anti-diarrhoeal activity in food allergy and inflammatory bowel disease. | British journal of pharmacology 20010801 |
Pro- and anti-inflammatory actions of ricinoleic acid: similarities and differences with capsaicin. | Naunyn-Schmiedeberg's archives of pharmacology 20010801 |
Large veins in the Atlantic cod (Gadus morhua) and the rainbow trout (Oncorhynchus mykiss) are innervated by neuropeptide-containing nerves. | Anatomy and embryology 20010801 |
Effect of calcitonin gene-related peptide (CGRP) on motility and on the release of substance P, neurokinin A, somatostatin and gastrin in the isolated perfused porcine antrum. | Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20010801 |
Direct evidence for the interaction of neurokinin A with the tachykinin NK(1) receptor in tissue. | European journal of pharmacology 20010706 |
Substance P and neurokinin A mediate sensory synaptic transmission in young rat dorsal horn neurons. | Brain research bulletin 20010701 |
The roles of the N-terminal portions of various tachykinins in promoting salivation. | Oral diseases 20010701 |
Developmental expression of neurokinin A and functional neurokinin-2 receptors in lung. | American journal of physiology. Lung cellular and molecular physiology 20010601 |
The protease-activated receptor-2 agonist induces gastric mucus secretion and mucosal cytoprotection. | The Journal of clinical investigation 20010601 |
An animal model to assess aversion to intra-oral capsaicin: increased threshold in mice lacking substance p. | Chemical senses 20010601 |
Physiology of meningeal innervation: aspects and consequences of chemosensitivity of meningeal nociceptors. | Microscopy research and technique 20010415 |
Potent NK1 antagonism by SR-140333 reduces rat colonic secretory response to immunocyte activation. | American journal of physiology. Cell physiology 20010401 |
Tachykinin activation of human monocytes from patients with rheumatoid arthritis: in vitro and ex-vivo effects of cyclosporin A. | Neuropeptides 20010401 |
Molecular and pharmacological characterization of the murine tachykinin NK(3) receptor. | European journal of pharmacology 20010216 |
Chronic tobacco smoke exposure increases airway sensitivity to capsaicin in awake guinea pigs. | Journal of applied physiology (Bethesda, Md. : 1985) 20010201 |
The N-terminal domain of substance P is required for complete homologous desensitization but not phosphorylation of the rat neurokinin-1 receptor. | Neuropeptides 20010201 |
Structure-activity relationships of neurokinin A (4-10) at the human tachykinin NK(2) receptor: the role of natural residues and their chirality. | Biochemical pharmacology 20010101 |
Tachykinins contribute to nerve-mediated contractions in the human esophagus. | Gastroenterology 20010101 |
Effect of tachykinins on airway function in cynomolgus monkeys. | Pulmonary pharmacology & therapeutics 20010101 |
Bronchoconstrictor reactivity to NKA in allergic dogs: a comparison to histamine and methacholine. | Pulmonary pharmacology & therapeutics 20010101 |
Involvement of spinal NK2 and NMDA receptors in aversive behavior induced by intra-arterial injection of capsaicin. | Pharmacology, biochemistry, and behavior 20010101 |
NK2 tachykinin receptors mediate contraction of the pig intravesical ureter: tachykinin-induced enhancement of non-adrenergic non-cholinergic excitatory neurotransmission. | Neurourology and urodynamics 20010101 |
Nitric oxide is generated in smooth muscle layer by neurokinin A and counteracts constriction in guinea pig airway. | Nitric oxide : biology and chemistry 20010101 |
Nitric oxide metabolites, prostaglandins and trigeminal vasoactive peptides in internal jugular vein blood during spontaneous migraine attacks. | Cephalalgia : an international journal of headache 20001201 |
Tachykinins in the porcine pancreas: potent exocrine and endocrine effects via NK-1 receptors. | Pancreas 20000401 |
Acute and chronic effects of capsaicin in perfused rat muscle: the role of tachykinins and calcitonin gene-related peptide. | The Journal of pharmacology and experimental therapeutics 19981101 |
p38 mitogen-activated protein kinase expression and activation in smooth muscle. | The American journal of physiology 19980801 |
Nociceptive inhibition of migrating myoelectric complex by nitric oxide and monoaminergic pathways in the rat. | The American journal of physiology 19980301 |
Nonpeptide tachykinin receptor antagonists: I. Pharmacological and pharmacokinetic characterization of SB 223412, a novel, potent and selective neurokinin-3 receptor antagonist. | The Journal of pharmacology and experimental therapeutics 19970601 |
Septide and neurokinin A are high-affinity ligands on the NK-1 receptor: evidence from homologous versus heterologous binding analysis. | FEBS letters 19961216 |
In vivo exposure to nitrogen dioxide (NO2) induces a decrease in calcitonin gene-related peptide (CGRP) and tachykinin immunoreactivity in guinea-pig peripheral airways. | The European respiratory journal 19960901 |
The unpredicted high affinities of a large number of naturally occurring tachykinins for chimeric NK1/NK3 receptors suggest a role for an inhibitory domain in determining receptor specificity. | The Journal of biological chemistry 19960823 |
Effects of neurokinin receptor antagonists on L-dopa induced bladder hyperactivity in normal conscious rats. | The Journal of urology 19951001 |
New spiropiperidines as potent and selective non-peptide tachykinin NK2 receptor antagonists. | Journal of medicinal chemistry 19950915 |
Neurokinin 1 and 2 antagonists attenuate the responses and NK1 antagonists prevent the sensitization of primate spinothalamic tract neurons after intradermal capsaicin. | Journal of neurophysiology 19941001 |
Cyclic hexapeptide NK-2 antagonists. | International journal of peptide and protein research 19940801 |
The non-peptide tachykinin NK2 receptor antagonist SR 48968 interacts with human, but not rat, cloned tachykinin NK3 receptors. | Biochemical and biophysical research communications 19940215 |
Expression of rat NK-2 (neurokinin A) receptor in E. coli. | Receptors & channels 19940101 |
Conformational study of cyclo[Gln-Trp-Phe-Gly-Leu-Met] as NK-2 antagonist by NMR and molecular dynamics. | Journal of pharmaceutical and biomedical analysis 19940101 |
Relative contributions of direct and indirect mechanisms mediating endothelin-induced contraction of guinea-pig trachea. | British journal of pharmacology 19931101 |
Characterization of the binding sites of [3H]SR 48968, a potent nonpeptide radioligand antagonist of the neurokinin-2 receptor. | Biochemical and biophysical research communications 19930331 |
Molecular basis for the species selectivity of the neurokinin-1 receptor antagonists CP-96,345 and RP67580. | The Journal of biological chemistry 19921225 |
Influence of (+/-)-CP-96,345 and SR 48968 on electrical field stimulation of the isolated guinea-pig main bronchus. | European journal of pharmacology 19921202 |
Structural characterization of tachykinins (neuropeptide gamma, neurokinin A, and substance P) from a reptile, Alligator mississipiensis. | General and comparative endocrinology 19921101 |
Nonadrenergic, noncholinergic contractile responses of the guinea pig hilar bronchus involve the preferential activation of tachykinin neurokinin2 receptors. | The Journal of pharmacology and experimental therapeutics 19920901 |
Highly potent and selective heptapeptide antagonists of the neurokinin NK-2 receptor. | Journal of medicinal chemistry 19920710 |
FK 224, a novel cyclopeptide substance P antagonist with NK1 and NK2 receptor selectivity. | The Journal of pharmacology and experimental therapeutics 19920701 |
Molecular characterisation, expression and localisation of human neurokinin-3 receptor. | FEBS letters 19920324 |
Stable expression of high affinity NK1 (substance P) and NK2 (neurokinin A) receptors but low affinity NK3 (neurokinin B) receptors in transfected CHO cells. | FEBS letters 19920127 |
A potent and selective non-peptide antagonist of the neurokinin A (NK2) receptor. | Life sciences 19920101 |
Studies of reflexogenic effects of capsaicin and neuropeptides on neural afferents in the dog parietal pericardium. | Neuropeptides 19911101 |
Receptors mediating tachykinin-induced contractile responses in guinea-pig trachea. | British journal of pharmacology 19910601 |
Antagonists for the neurokinin NK-3 receptor evaluated in selective receptor systems. | Regulatory peptides 19901115 |
Competitive antagonists discriminate between NK2 tachykinin receptor subtypes. | British journal of pharmacology 19900701 |
Structure-activity study of neurokinins: antagonists for the neurokinin-2 receptor. | Pharmacology 19900101 |
[Arg3]substance P and neurokinin A from chicken small intestine. | Regulatory peptides 19880201 |
Different receptors are involved in the endothelium-mediated relaxation and the smooth muscle contraction of the rabbit pulmonary artery in response to substance P and related neurokinins. | European journal of pharmacology 19860605 |
A rat brain isozyme of angiotensin-converting enzyme. Unique specificity for amidated peptide substrates. | The Journal of biological chemistry 19850815 |
Neuromedin L: a novel mammalian tachykinin identified in porcine spinal cord. | Neuropeptides 19840301 |
Synthesis and biological activities of neurokinin alpha and beta. | Biochemical and biophysical research communications 19840130 |