sales@angenesci.com
Login | Register
logo
Structures Search
Home Other Building Blocks Hc-067047

Hc-067047

CAS No.:
883031-03-6
Catalog Number:
AG00495X
Molecular Formula:
C26H28F3N3O2
Molecular Weight:
471.5146
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1mg
≥98%
1 week
United States
$91
- +
5mg
≥98%
1 week
United States
$135
- +
10mg
≥98%
1 week
United States
$196
- +
25mg
≥98%
1 week
United States
$361
- +
100mg
99%
1 week
United States
$1223
- +
Product Description
Catalog Number:
AG00495X
Chemical Name:
Hc-067047
CAS Number:
883031-03-6
Molecular Formula:
C26H28F3N3O2
Molecular Weight:
471.5146
MDL Number:
MFCD01571257
IUPAC Name:
2-methyl-1-(3-morpholin-4-ylpropyl)-5-phenyl-N-[3-(trifluoromethyl)phenyl]pyrrole-3-carboxamide
InChI:
InChI=1S/C26H28F3N3O2/c1-19-23(25(33)30-22-10-5-9-21(17-22)26(27,28)29)18-24(20-7-3-2-4-8-20)32(19)12-6-11-31-13-15-34-16-14-31/h2-5,7-10,17-18H,6,11-16H2,1H3,(H,30,33)
InChI Key:
NCZYSQOTAYFTNM-UHFFFAOYSA-N
SMILES:
O=C(c1cc(n(c1C)CCCN1CCOCC1)c1ccccc1)Nc1cccc(c1)C(F)(F)F
Properties
Complexity:
650  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
471.213g/mol
Formal Charge:
0
Heavy Atom Count:
34  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
471.524g/mol
Monoisotopic Mass:
471.213g/mol
Rotatable Bond Count:
7  
Topological Polar Surface Area:
46.5A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
4.4  
Literature
Title Journal
Activation of TRPV3 by Wood Smoke Particles and Roles in Pneumotoxicity. Chemical research in toxicology 20180521
Identification of potent Yes1 kinase inhibitors using a library screening approach. Bioorganic & medicinal chemistry letters 20130801
Implication of the ryanodine receptor in TRPV4-induced calcium response in pulmonary arterial smooth muscle cells from normoxic and chronically hypoxic rats. American journal of physiology. Lung cellular and molecular physiology 20121101
Involvement of TRPV1 and TRPV4 channels in migration of rat pulmonary arterial smooth muscle cells. Pflugers Archiv : European journal of physiology 20120901
TRPV4 in porcine lens epithelium regulates hemichannel-mediated ATP release and Na-K-ATPase activity. American journal of physiology. Cell physiology 20120615
TRPA1 and TRPV4 mediate paclitaxel-induced peripheral neuropathy in mice via a glutathione-sensitive mechanism. Pflugers Archiv : European journal of physiology 20120401
Inhibition of the cation channel TRPV4 improves bladder function in mice and rats with cyclophosphamide-induced cystitis. Proceedings of the National Academy of Sciences of the United States of America 20101102
Properties