4,8-Dihydroxyquinoline-2-carboxylic acid
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Metabolomic analysis of biochemical changes in the plasma and urine of collagen-induced arthritis in rats after treatment with Huang-Lian-Jie-Du-Tang. | Journal of ethnopharmacology 20140528 |
Metabonomics evaluation of urine from rats administered with phorate under long-term and low-level exposure by ultra-performance liquid chromatography-mass spectrometry. | Journal of applied toxicology : JAT 20140201 |
A urinary metabonomics study on biochemical changes in yeast-induced pyrexia rats: a new approach to elucidating the biochemical basis of the febrile response. | Chemico-biological interactions 20130625 |
On the autofluorescence of fingermarks. | Forensic science international 20121010 |
Apicomplexan parasite, Eimeria falciformis, co-opts host tryptophan catabolism for life cycle progression in mouse. | The Journal of biological chemistry 20120608 |
Maternal tryptophan and kynurenine pathway metabolites and risk of preeclampsia. | Obstetrics and gynecology 20120601 |
Harmonine, a defence compound from the harlequin ladybird, inhibits mycobacterial growth and demonstrates multi-stage antimalarial activity. | Biology letters 20120423 |
NMR in metabolomics and natural products research: two sides of the same coin. | Accounts of chemical research 20120221 |
A putative homologue of CDC20/CDH1 in the malaria parasite is essential for male gamete development. | PLoS pathogens 20120201 |
Ultrasensitive indicator-free and enhanced self-signal nanohybrid DNA sensing platform based on electrochemically grown poly-xanthurenic acid/Fe2O3 membranes. | Biosensors & bioelectronics 20120115 |
Amides of xanthurenic acid as zinc-dependent inhibitors of Lp-PLA(2). | Bioorganic & medicinal chemistry letters 20120115 |
Xanthurenic acid is an endogenous substrate for the silkworm cytosolic sulfotransferase, bmST1. | Journal of insect physiology 20120101 |
Sexual development in Plasmodium: lessons from functional analyses. | PLoS pathogens 20120101 |
The biology of sexual development of Plasmodium: the design and implementation of transmission-blocking strategies. | Malaria journal 20120101 |
Salivary gland-specific P. berghei reporter lines enable rapid evaluation of tissue-specific sporozoite loads in mosquitoes. | PloS one 20120101 |
The antioxidant role of xanthurenic acid in the Aedes aegypti midgut during digestion of a blood meal. | PloS one 20120101 |
Tryptophan in alcoholism treatment II: inhibition of the rat liver mitochondrial low Km aldehyde dehydrogenase activity, elevation of blood acetaldehyde concentration and induction of aversion to alcohol by combined administration of tryptophan and benserazide. | Alcohol and alcoholism (Oxford, Oxfordshire) 20111101 |
Tryptophan in alcoholism treatment I: kynurenine metabolites inhibit the rat liver mitochondrial low Km aldehyde dehydrogenase activity, elevate blood acetaldehyde concentration and induce aversion to alcohol. | Alcohol and alcoholism (Oxford, Oxfordshire) 20111101 |
Simultaneous determination of tryptophan, kynurenine, kynurenic and xanthurenic acids in honey by liquid chromatography with diode array, fluorescence and tandem mass spectrometry detection. | Journal of chromatography. A 20111021 |
UPLC-MS-based urine metabolomics reveals indole-3-lactic acid and phenyllactic acid as conserved biomarkers for alcohol-induced liver disease in the Ppara-null mouse model. | Journal of proteome research 20110902 |
Multiple roles for Plasmodium berghei phosphoinositide-specific phospholipase C in regulating gametocyte activation and differentiation. | Cellular microbiology 20110701 |
Untargeted metabolomics identifies enterobiome metabolites and putative uremic toxins as substrates of organic anion transporter 1 (Oat1). | Journal of proteome research 20110603 |
Urinary metabonomics study of anti-depressive effect of Chaihu-Shu-Gan-San on an experimental model of depression induced by chronic variable stress in rats. | Journal of pharmaceutical and biomedical analysis 20110601 |
Malaria proteases mediate inside-out egress of gametocytes from red blood cells following parasite transmission to the mosquito. | Cellular microbiology 20110601 |
Kynurenine metabolites and migraine: experimental studies and therapeutic perspectives. | Current neuropharmacology 20110601 |
Transition of Plasmodium sporozoites into liver stage-like forms is regulated by the RNA binding protein Pumilio. | PLoS pathogens 20110501 |
Quinolones: from antibiotics to autoinducers. | FEMS microbiology reviews 20110301 |
Assessment of vitamin B(6) status in Korean patients with newly diagnosed type 2 diabetes. | Nutrition research and practice 20110201 |
Identification of urinary biomarkers of colon inflammation in IL10-/- mice using Short-Column LCMS metabolomics. | Journal of biomedicine & biotechnology 20110101 |
Metabolomic study of a rat fever model induced with 2,4-dinitrophenol and the therapeutic effects of a crude drug derived from Coptis chinensis. | The American journal of Chinese medicine 20110101 |
Fluorescent derivatization of xanthurenic acid and nicotinic acid with horseradish peroxidase in the presence of excess hydrogen peroxide. | Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20110101 |
System in biology leading to cell pathology: stable protein-protein interactions after covalent modifications by small molecules or in transgenic cells. | Journal of biomedical science 20110101 |
Association of kynurenine aminotransferase II gene C401T polymorphism with immune response in patients with meningitis. | BMC medical genetics 20110101 |
The Puf-family RNA-binding protein Puf2 controls sporozoite conversion to liver stages in the malaria parasite. | PloS one 20110101 |
A biological pathway linking inflammation and depression: activation of indoleamine 2,3-dioxygenase. | Neuropsychiatric disease and treatment 20110101 |
Optical effects of exposing intact human lenses to ultraviolet radiation and visible light. | BMC ophthalmology 20110101 |
Optimized in vitro production of Plasmodium vivax ookinetes. | The American journal of tropical medicine and hygiene 20101206 |
Dual role of the carboxyl-terminal region of pig liver L-kynurenine 3-monooxygenase: mitochondrial-targeting signal and enzymatic activity. | Journal of biochemistry 20101201 |
Metabolomics identifies novel Hnf1alpha-dependent physiological pathways in vivo. | Molecular endocrinology (Baltimore, Md.) 20101201 |
Effect of melatonin and caffeine interaction on caffeine induced oxidative stress and sleep disorders. | Nigerian journal of physiological sciences : official publication of the Physiological Society of Nigeria 20101124 |
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. | Bioorganic & medicinal chemistry letters 20101101 |
The systematic functional analysis of Plasmodium protein kinases identifies essential regulators of mosquito transmission. | Cell host & microbe 20101021 |
Neurotoxins: free radical mechanisms and melatonin protection. | Current neuropharmacology 20100901 |
Photoinduced tautomeric transformations of xanthurenic acid. | Physical chemistry chemical physics : PCCP 20100828 |
Kynurenic acid is a potent endogenous aryl hydrocarbon receptor ligand that synergistically induces interleukin-6 in the presence of inflammatory signaling. | Toxicological sciences : an official journal of the Society of Toxicology 20100501 |
Metabolomic analysis identifies inflammatory and noninflammatory metabolic effects of genetic modification in a mouse model of Crohn's disease. | Journal of proteome research 20100405 |
A systems-based analysis of Plasmodium vivax lifecycle transcription from human to mosquito. | PLoS neglected tropical diseases 20100401 |
Radioprotectors and mitigators of radiation-induced normal tissue injury. | The oncologist 20100401 |
Life cycle studies of the hexose transporter of Plasmodium species and genetic validation of their essentiality. | Molecular microbiology 20100301 |
Urinary metabonomic study on biochemical changes in chronic unpredictable mild stress model of depression. | Clinica chimica acta; international journal of clinical chemistry 20100201 |
The coming-out of malaria gametocytes. | Journal of biomedicine & biotechnology 20100101 |
A semi-automated method for counting fluorescent malaria oocysts increases the throughput of transmission blocking studies. | Malaria journal 20100101 |
Flow cytometry for the evaluation of anti-plasmodial activity of drugs on Plasmodium falciparum gametocytes. | Malaria journal 20100101 |
An improved method for the in vitro differentiation of Plasmodium falciparum gametocytes into ookinetes. | Malaria journal 20100101 |
Circulating Antibodies to IDO/THO Pathway Metabolites in Alzheimer's Disease. | International journal of Alzheimer's disease 20100101 |
The Armadillo repeat protein PF16 is essential for flagellar structure and function in Plasmodium male gametes. | PloS one 20100101 |
Apoptosis stalks Plasmodium falciparum maintained in continuous culture condition. | Malaria journal 20100101 |
Promiscuous expression of α-tubulin II in maturing male and female Plasmodium falciparum gametocytes. | PloS one 20100101 |
Tryptophan, Neurodegeneration and HIV-Associated Neurocognitive Disorder. | International journal of tryptophan research : IJTR 20100101 |
Rapid Isocratic Liquid Chromatographic Separation and Quantification of Tryptophan and Six kynurenine Metabolites in Biological Samples with Ultraviolet and Fluorimetric Detection. | International journal of tryptophan research : IJTR 20100101 |
Characterization of Plasmodium falciparum calcium-dependent protein kinase 4. | Parasitology international 20091201 |
Vital role for the Plasmodium actin capping protein (CP) beta-subunit in motility of malaria sporozoites. | Molecular microbiology 20091201 |
Quantitative assessment of DNA replication to monitor microgametogenesis in Plasmodium berghei. | Molecular and biochemical parasitology 20091201 |
Cloning and molecular characterization of tick kynurenine aminotransferase (HlKAT) from Haemaphysalis longicornis (Acari: Ixodidae). | Parasitology research 20090901 |
A cyclic GMP signalling module that regulates gliding motility in a malaria parasite. | PLoS pathogens 20090901 |
An essential role for the Plasmodium Nek-2 Nima-related protein kinase in the sexual development of malaria parasites. | The Journal of biological chemistry 20090731 |
Quantitative profiling of biomarkers related to B-vitamin status, tryptophan metabolism and inflammation in human plasma by liquid chromatography/tandem mass spectrometry. | Rapid communications in mass spectrometry : RCM 20090501 |
Nontargeted urinary metabolite profiling of a mouse model of Crohn's disease. | Journal of proteome research 20090401 |
Combination of 1H nuclear magnetic resonance spectroscopy and liquid chromatography/mass spectrometry with pattern recognition techniques for evaluation of metabolic profile associated with albuminuria. | Journal of proteome research 20090401 |
Trypanosoma brucei brucei: effects of ferrous iron and heme on ecto-nucleoside triphosphate diphosphohydrolase activity. | Experimental parasitology 20090201 |
Structure and non-essential function of glycerol kinase in Plasmodium falciparum blood stages. | Molecular microbiology 20090101 |
Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases. | BMC medical genomics 20090101 |
Unlike the synchronous Plasmodium falciparum and P. chabaudi infection, the P. berghei and P. yoelii asynchronous infections are not affected by melatonin. | International journal of general medicine 20090101 |
Photoactivity of kynurenine-derived UV filters. | Journal of photochemistry and photobiology. B, Biology 20081211 |
Analysis of urinary aromatic acids by liquid chromatography tandem mass spectrometry. | Biomedical chromatography : BMC 20081201 |
Involvement of ST1B subfamily of cytosolic sulfotransferase in kynurenine metabolism to form natriuretic xanthurenic acid sulfate. | The Journal of pharmacology and experimental therapeutics 20081201 |
Reverse genetics screen identifies six proteins important for malaria development in the mosquito. | Molecular microbiology 20081001 |
Characterization of the 3-HKT gene in important malaria vectors in India, viz: Anopheles culicifacies and Anopheles stephensi (Diptera: Culicidae). | Memorias do Instituto Oswaldo Cruz 20080901 |
Disruption of a Plasmodium falciparum cyclic nucleotide phosphodiesterase gene causes aberrant gametogenesis. | Molecular microbiology 20080701 |
Gametogenesis in malaria parasites is mediated by the cGMP-dependent protein kinase. | PLoS biology 20080601 |
Xanthurenic acid distribution, transport, accumulation and release in the rat brain. | Journal of neurochemistry 20080501 |
Pyridoxine-related metabolite concentrations in normal and Down syndrome amniotic fluid. | Fetal diagnosis and therapy 20080501 |
Indoleamine 2,3-dioxygenase-dependent tryptophan metabolites contribute to tolerance induction during allergen immunotherapy in a mouse model. | The Journal of allergy and clinical immunology 20080401 |
Plasmodium falciparum regulatory subunit of cAMP-dependent PKA and anion channel conductance. | PLoS pathogens 20080201 |
Genomic, genetic and structural analysis of pyoverdine-mediated iron acquisition in the plant growth-promoting bacterium Pseudomonas fluorescens SBW25. | BMC microbiology 20080101 |
Genome-wide detection of serpentine receptor-like proteins in malaria parasites. | PloS one 20080101 |
Plasmodium falciparum antigens on the surface of the gametocyte-infected erythrocyte. | PloS one 20080101 |
The immune effects of TRYCATs (tryptophan catabolites along the IDO pathway): relevance for depression - and other conditions characterized by tryptophan depletion induced by inflammation. | Neuro endocrinology letters 20071201 |
Hemolytic C-type lectin CEL-III from sea cucumber expressed in transgenic mosquitoes impairs malaria parasite development. | PLoS pathogens 20071201 |
Minimum requirements for ookinete to oocyst transformation in Plasmodium. | International journal for parasitology 20070901 |
Metabolomic and genetic analysis of biomarkers for peroxisome proliferator-activated receptor alpha expression and activation. | Molecular endocrinology (Baltimore, Md.) 20070901 |
Effect of nicotinamide administration on the tryptophan-nicotinamide pathway in humans. | International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 20070701 |
Xanthurenic aciduria due to a mutation in KYNU encoding kynureninase. | Journal of inherited metabolic disease 20070401 |
The tryptophan oxidation pathway in mosquitoes with emphasis on xanthurenic acid biosynthesis. | Journal of insect physiology 20070301 |
An annotated catalogue of salivary gland transcripts in the adult female mosquito, Aedes aegypti. | BMC genomics 20070101 |
Small but versatile: the extraordinary functional and structural diversity of the beta-grasp fold. | Biology direct 20070101 |
Crystal structures of Aedes aegypti alanine glyoxylate aminotransferase. | The Journal of biological chemistry 20061201 |
Prooxidant action of xanthurenic acid and quinoline compounds: role of transition metals in the generation of reactive oxygen species and enhanced formation of 8-hydroxy-2'-deoxyguanosine in DNA. | Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20060801 |
The effects of blood feeding and exogenous supply of tryptophan on the quantities of xanthurenic acid in the salivary glands of Anopheles stephensi (Diptera: Culicidae). | Biochemical and biophysical research communications 20060324 |
Plasmodium development in white-eye (kh(w)) and transformed strains (kh43) of Aedes aegypti (Diptera: Culicidae). | Journal of medical entomology 20060301 |
Melatonin in Alzheimer's disease and other neurodegenerative disorders. | Behavioral and brain functions : BBF 20060101 |
[Metabolite fingerprint and biomarkers identification of rat urine after dosed with ginsenoside Rg3 based on ultra high performance liquid chromatography/time-of-flight mass spectrometry (UPLC/TOF-MS)]. | Se pu = Chinese journal of chromatography 20060101 |
The prokaryotic antecedents of the ubiquitin-signaling system and the early evolution of ubiquitin-like beta-grasp domains. | Genome biology 20060101 |
Murine renal organic anion transporters mOAT1 and mOAT3 facilitate the transport of neuroactive tryptophan metabolites. | American journal of physiology. Cell physiology 20051101 |
Identification and biochemical characterization of the Anopheles gambiae 3-hydroxykynurenine transaminase. | The FEBS journal 20051101 |
Prediction of genotoxicity of chemical compounds by statistical learning methods. | Chemical research in toxicology 20050601 |
D-Serine-induced nephrotoxicity: a HPLC-TOF/MS-based metabonomics approach. | Toxicology 20050214 |
Separation and determination of L-tryptophan and its metabolites by capillary micellar electrokinetic chromatography with amperometric detection. | Electrophoresis 20050201 |
Metabonomics with 1H-NMR spectroscopy and liquid chromatography-mass spectrometry applied to the investigation of metabolic changes caused by gentamicin-induced nephrotoxicity in the rat. | Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20050101 |
Pyridoxine supplementation corrects vitamin B6 deficiency but does not improve inflammation in patients with rheumatoid arthritis. | Arthritis research & therapy 20050101 |
Effects of some naturally occurring iron ion chelators on in vitro superoxide radical formation. | Biological trace element research 20050101 |
Synthesis and iron-binding properties of quinolobactin, a siderophore from a pyoverdine-deficient Pseudomonas fluorescens. | Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20041201 |
Tracheal tone and the role of ionotropic glutamate receptors in the nucleus ambiguus. | Brain research 20040917 |
Comment on 'The photosensitiser xanthurenic acid is not present in normal human lenses' by P.G. Hains et al. [Exp. Eye Res. 77 (2003) 547-553]. | Experimental eye research 20040901 |
A metabonomic investigation of the biochemical effects of mercuric chloride in the rat using 1H NMR and HPLC-TOF/MS: time dependent changes in the urinary profile of endogenous metabolites as a result of nephrotoxicity. | The Analyst 20040601 |
Cyclosporin A-induced changes in endogenous metabolites in rat urine: a metabonomic investigation using high field 1H NMR spectroscopy, HPLC-TOF/MS and chemometrics. | Journal of pharmaceutical and biomedical analysis 20040528 |
Gamete interruptus; a novel calcium-dependent kinase is essential for malaria sexual reproduction. | Cell 20040514 |
Calcium and a calcium-dependent protein kinase regulate gamete formation and mosquito transmission in a malaria parasite. | Cell 20040514 |
The Pseudomonas siderophore quinolobactin is synthesized from xanthurenic acid, an intermediate of the kynurenine pathway. | Molecular microbiology 20040401 |
Xanthurenic acid translocates proapoptotic Bcl-2 family proteins into mitochondria and impairs mitochondrial function. | BMC cell biology 20040101 |
The photosensitiser xanthurenic acid is not present in normal human lenses. | Experimental eye research 20031101 |
Abnormal signalling of 14-3-3 proteins in cells with accumulated xanthurenic acid. | Biochemical and biophysical research communications 20031017 |
Melatonin, xanthurenic acid, resveratrol, EGCG, vitamin C and alpha-lipoic acid differentially reduce oxidative DNA damage induced by Fenton reagents: a study of their individual and synergistic actions. | Journal of pineal research 20030501 |
Sex-specific and blood meal-induced proteins of Anopheles gambiae midguts: analysis by two-dimensional gel electrophoresis. | Malaria journal 20030101 |
Neurokynurenines--seizures or/and anxiety in children with epilepsy? | Advances in experimental medicine and biology 20030101 |
Kynurenine and neopterin levels in patients with rheumatoid arthritis and osteoporosis during drug treatment. | Advances in experimental medicine and biology 20030101 |
Levels of purine, kynurenine and lipid peroxidation products in patients with inflammatory bowel disease. | Advances in experimental medicine and biology 20030101 |
Increase in conversion of tryptophan to niacin in pregnant rats. | Advances in experimental medicine and biology 20030101 |
The effects of phthalate esters on the tryptophan-niacin metabolism. | Advances in experimental medicine and biology 20030101 |
Photochemical properties of kynurenine pathway metabolites and indoleamines. | Advances in experimental medicine and biology 20030101 |
Formation of kynurenic and xanthurenic acids from kynurenine and 3-hydroxykynurenine in the dinoflagellate Lingulodinium polyedrum: role of a novel, oxidative pathway. | Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20021101 |
cDNA cloning, functional expression and characterization of kynurenine 3-hydroxylase of Anopheles stephensi (Diptera: Culicidae). | Insect molecular biology 20021001 |
Role of xanthurenic acid 8-O-beta-D-glucoside, a novel fluorophore that accumulates in the brunescent human eye lens. | Photochemistry and photobiology 20020901 |
Growth-promoting activity of pyrazinoic acid, a putative active compound of antituberculosis drug pyrazinamide, in niacin-deficient rats through the inhibition of ACMSD activity. | Bioscience, biotechnology, and biochemistry 20020701 |
Synthesis and in vitro pharmacology of substituted quinoline-2,4-dicarboxylic acids as inhibitors of vesicular glutamate transport. | Journal of medicinal chemistry 20020523 |
3-Hydroxykynurenine transaminase identity with alanine glyoxylate transaminase. A probable detoxification protein in Aedes aegypti. | The Journal of biological chemistry 20020503 |
Tryptophan metabolism via the kynurenine pathway in experimental chronic renal failure. | Nephron 20020301 |
Effect of pyruvate on the function of stallion spermatozoa stored for up to 48 hours. | Journal of animal science 20020101 |
Lens epithelial cell apoptosis and intracellular Ca2+ increase in the presence of xanthurenic acid. | BMC ophthalmology 20020101 |
Kynurenine aminotransferase and glutamine transaminase K of Escherichia coli: identity with aspartate aminotransferase. | The Biochemical journal 20011215 |
Kynurenine and its metabolites in the rat with experimental renal insufficiency. | Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20011201 |
Ocular phototoxicity. | Journal of photochemistry and photobiology. B, Biology 20011115 |
Photooxidation of lens proteins with xanthurenic acid: a putative chromophore for cataractogenesis. | Photochemistry and photobiology 20011101 |
Characterization and identification of exflagellation-inducing factor in the salivary gland of Anopheles stephensi (Diptera: Culicidae). | Biochemical and biophysical research communications 20011005 |
The gametocyte-activating factor xanthurenic acid stimulates an increase in membrane-associated guanylyl cyclase activity in the human malaria parasite Plasmodium falciparum. | Molecular microbiology 20011001 |
Influence of adenine-induced renal failure on tryptophan-niacin metabolism in rats. | Bioscience, biotechnology, and biochemistry 20011001 |
Toxicologic significance of the hyperglycemia caused by organophosphorous insecticides. | Bulletin of environmental contamination and toxicology 20011001 |
Identification of a novel fluorophore, xanthurenic acid 8- O -beta-D-glucoside in human brunescent cataract. | Experimental eye research 20011001 |
Effect of xanthurenic acid on infectivity of Plasmodium falciparum to Anopheles stephensi. | International journal for parasitology 20010801 |
Both mosquito-derived xanthurenic acid and a host blood-derived factor regulate gametogenesis of Plasmodium in the midgut of the mosquito. | Molecular and biochemical parasitology 20010801 |
Development of a method for the in vitro production of Plasmodium vivax ookinetes. | The Journal of parasitology 20010801 |
Xanthurenic acid inhibits metal ion-induced lipid peroxidation and protects NADP-isocitrate dehydrogenase from oxidative inactivation. | Journal of nutritional science and vitaminology 20010801 |
Effects of dietary pyrazinamide, an antituberculosis agent, on the metabolism of tryptophan to niacin and of tryptophan to serotonin in rats. | Bioscience, biotechnology, and biochemistry 20010601 |
[Effect of feeding with a poisonous mushroom Clitocybe acromelalga on the metabolism of tryptophan-niacin in rats]. | Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20010601 |
Effects of long-term parenteral administration of vitamin B6 on B6 status and some aspects of the glucose and protein metabolism of early-weaned piglets. | The British journal of nutrition 20010101 |
Pathological apoptosis by xanthurenic acid, a tryptophan metabolite: activation of cell caspases but not cytoskeleton breakdown. | BMC physiology 20010101 |
Accumulation of toxic products degradation of kynurenine in hemodialyzed patients. | International urology and nephrology 20010101 |
Antagonism of kynurenine-induced seizures by picolinic, kynurenic and xanthurenic acids. | Journal of neural transmission 19830101 |