Tropisetron attenuates cardiac injury in a rat trauma-hemorrhage model.

Shock (Augusta, Ga.) 20120701

Tropisetron and paracetamol association in post-operative patients.

Fundamental & clinical pharmacology 20120601

Combination of dexamethasone and tropisetron before thyroidectomy to alleviate postoperative nausea, vomiting, and pain: randomized controlled trial.

World journal of surgery 20120601

Regulation of respiratory-related hypoglossal motor output by α₁ adrenergic and serotonin 5-HT₃ receptor activation in isolated adult turtle brainstems.

Respiratory physiology & neurobiology 20120430

[Comparison of the effect of palonosetron versus tropisetron in prevention of vomiting in patients receiving high dose cisplatin-based chemotherapy].

Zhonghua zhong liu za zhi [Chinese journal of oncology] 20120301

Effects of OCT1 polymorphisms on the cellular uptake, plasma concentrations and efficacy of the 5-HT(3) antagonists tropisetron and ondansetron.

The pharmacogenomics journal 20120201

Effect of intravenous tropisetron on modulation of pain and central hypersensitivity in chronic low back pain patients.

Pain 20120201

One failed clinical trial (of 5HT3 antagonists) does not invalidate the concept.

Pain 20120201

Synergistic self-administration of ethanol and cocaine directly into the posterior ventral tegmental area: involvement of serotonin-3 receptors.

The Journal of pharmacology and experimental therapeutics 20120101

[Low-dose droperidol in children: rescue therapy for persistent postoperative nausea and vomiting].

Der Anaesthesist 20120101

Protective effect of tropisetron on rodent hepatic injury after trauma-hemorrhagic shock through P38 MAPK-dependent hemeoxygenase-1 expression.

PloS one 20120101

Serotonin receptor type 3 antagonists improve obesity-associated fatty liver disease in mice.

The Journal of pharmacology and experimental therapeutics 20111201

Experimental examination of anti-inflammatory effects of a 5-HT3 receptor antagonist, tropisetron, and concomitant effects on autonomic nervous function in a rat sepsis model.

International immunopharmacology 20111201

Tropisetron upregulates cannabinoid CB1 receptors in cerebellar granule cells: possible involvement of calcineurin.

Brain research 20111012

Short-term synaptic plasticity regulates the level of olivocochlear inhibition to auditory hair cells.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20111012

Synergistic antiemetic interactions between serotonergic 5-HT3 and tachykininergic NK1-receptor antagonists in the least shrew (Cryptotis parva).

Pharmacology, biochemistry, and behavior 20111001

Tropisetron versus metoclopramide for the treatment of nausea and vomiting in the emergency department: A randomized, double-blinded, clinical trial.

Emergency medicine Australasia : EMA 20111001

Prophylaxis of postoperative nausea and vomiting in elective breast surgery.

Journal of clinical anesthesia 20110901

The stimulating effects of ethanol on ventral tegmental area dopamine neurons projecting to the ventral pallidum and medial prefrontal cortex in female Wistar rats: regional difference and involvement of serotonin-3 receptors.

Psychopharmacology 20110701

Lack of long-term behavioral alterations after early postnatal treatment with tropisetron: implications for developmental psychobiology.

Pharmacology, biochemistry, and behavior 20110701

Acetylcholine and norepinephrine mediate GABAergic but not glycinergic transmission enhancement by melittin in adult rat substantia gelatinosa neurons.

Journal of neurophysiology 20110701

Tropisetron increases the inhibitory effect of mild restraint on lordosis behavior of hormonally primed, ovariectomized rats.

Behavioural brain research 20110601

Tropisetron blocks analgesic action of acetaminophen: a human pain model study.

Pain 20110601

Antiemetic prophylaxis in thyroid surgery: a randomized, double-blind comparison of three 5-HT3 agents.

Journal of anesthesia 20110601

The role of 5-HT(3) receptors in the additive anticonvulsant effects of citalopram and morphine on pentylenetetrazole-induced clonic seizures in mice.

Epilepsy & behavior : E&B 20110601

Tropisetron ameliorates ischemic brain injury in an embolic model of stroke.

Brain research 20110525

Mode of action of peppermint oil and (-)-menthol with respect to 5-HT3 receptor subtypes: binding studies, cation uptake by receptor channels and contraction of isolated rat ileum.

Phytotherapy research : PTR 20110501

The pyramidal neurons in the medial prefrontal cortex show decreased response to 5-hydroxytryptamine-3 receptor stimulation in a rodent model of Parkinson's disease.

Brain research 20110412

A randomized comparison of droperidol, metoclopramide, tropisetron, and ondansetron for the prevention of postoperative nausea and vomiting.

Gynecologic and obstetric investigation 20110101

[Development of new therapeutic drugs based on the pathophysiology of schizophrenia].

Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica 20110101

Ameliorating effects of tropisetron on dopaminergic disruption of prepulse inhibition via the alpha(7) nicotinic acetylcholine receptor in Wistar rats.

Brain research 20100924

Cardiovascular effects of a novel synthetic analogue of naturally occurring piperamides.

Journal of cardiovascular pharmacology 20100901

Differential responses to serotonin receptor ligands in an impulsive-aggressive phenotype.

Behavioral neuroscience 20100801

Anti-emetic doses of dexamethasone suppress cortisol response in laparoscopic cholecystectomy.

Anaesthesia and intensive care 20100701

5-HT3 receptor-dependent modulation of respiratory burst frequency, regularity, and episodicity in isolated adult turtle brainstems.

Respiratory physiology & neurobiology 20100630

Nausea and vomiting in advanced cancer.

The American journal of hospice & palliative care 20100501

Serotonin reuptake transporter (SERT) plays a critical role in the onset of fructose-induced hepatic steatosis in mice.

American journal of physiology. Gastrointestinal and liver physiology 20100301

A comparative study of prophylactic antiemetic treatment in cancer patients receiving radiotherapy.

Journal of B.U.ON. : official journal of the Balkan Union of Oncology 20100101

Changes in characteristics of the specific binding of [3H]LY-278584, a 5-HT3-receptor antagonist, on differentiated NG108-15 cells.

Journal of pharmacological sciences 20100101

HPLC, TLC, and first-derivative spectrophotometry stability-indicating methods for the determination of tropisetron in the presence of its acid degradates.

Journal of AOAC International 20100101

Arylalkylamine-, beta-carboline-, quinolizine- and azecine-derived compounds and their in vitro interaction with the ionotropic 5-HT3 receptor: search for new lead structures.

Arzneimittel-Forschung 20100101

Impact of the 5-HT3 receptor channel system for insulin secretion and interaction of ginger extracts.

European journal of pharmacology 20091210

Treatment with the 5-HT3 antagonist tropisetron modulates glucose-induced obesity in mice.

International journal of obesity (2005) 20091201

Receptor occupancy theory-based analysis of interindividual differences in antiemetic effects of 5-HT3 receptor antagonists.

International journal of clinical oncology 20091201

Structural determinants for interaction of partial agonists with acetylcholine binding protein and neuronal alpha7 nicotinic acetylcholine receptor.

The EMBO journal 20091007

Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

Nature chemical biology 20091001

Different binding modes of tropeines mediating inhibition and potentiation of alpha1 glycine receptors.

Journal of neurochemistry 20090601

Anti-inflammatory effects of 5-HT receptor antagonist, tropisetron on experimental colitis in rats.

European journal of clinical investigation 20090501

Tropisetron attenuates naloxone-induced place aversion in single-dose morphine-treated rats: role of alpha7 nicotinic receptors.

European journal of pharmacology 20090501

Determination of tropisetron in human plasma by liquid chromatography-tandem mass spectrometry.

Journal of pharmaceutical and biomedical analysis 20090405

[Nicotinic acetylcholine receptors are possible therapeutic targets for schizophrenia].

Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20090201

The antiemetic interaction of Delta9-tetrahydrocannabinol when combined with tropisetron or dexamethasone in the least shrew.

Pharmacology, biochemistry, and behavior 20090101

Tropisetron plus subhypnotic propofol infusion is more effective than tropisetron alone for the prevention of vomiting in children after tonsillectomy.

Anaesthesia and intensive care 20090101

Modulation of paracetamol and nefopam antinociception by serotonin 5-HT(3) receptor antagonists in mice.

Pharmacology 20090101

Excitability of small-diameter trigeminal ganglion neurons by 5-HT is mediated by enhancement of the tetrodotoxin-resistant sodium current due to the activation of 5-HT(4) receptors and/or by the inhibition of the transient potassium current.

Neuroscience 20081202

Myocardial ischemia-mediated excitatory reflexes: a new function for thromboxane A2?

American journal of physiology. Heart and circulatory physiology 20081201

Effect of two artichoke extracts (36_U and 36_EB) on rat ileum (with respect to bowel syndrome) and the peristaltic threshold.

Phytomedicine : international journal of phytotherapy and phytopharmacology 20081101

Long-term depression in the superior cervical ganglion of the rat.

Brain research 20081009

Broad complex tachycardia and tropisteron.

European journal of anaesthesiology 20081001

The acute effect of tropisetron on ECG parameters in cancer patients.

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20080901

Serotonin mediates PGE2 overexpression through 5-HT2A and 5-HT3 receptor subtypes in serum-free tissue culture of macrophage-like synovial cells.

Rheumatology international 20080801

Zinc modulation of glycine receptors in acutely isolated rat CA3 neurons.

Life sciences 20080801

5-HT3 receptor antagonist for the treatment of tendinopathy.

Nature clinical practice. Rheumatology 20080701

Cutaneous adverse drug reactions during chemotherapy: consider non-antineoplastic drugs.

Contact dermatitis 20080601

5-HT3 receptor antagonist for the treatment of tendinopathy.

Nature clinical practice. Rheumatology 20080601

Downregulated hypothalamic 5-HT3 receptor expression and enhanced 5-HT3 receptor antagonist-mediated improvement in fatigue-like behaviour in cholestatic rats.

Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20080301

Efficacy of tropisetron in patients with advanced non-small-cell lung cancer receiving adjuvant chemotherapy with carboplatin and taxanes.

European journal of cancer care 20080301

Detrimental effects of tropisetron on permanent ischemic stroke in the rat.

BMC neuroscience 20080101

[Pharmacokinetic and pharmacodynamic features of palonosetron].

Tumori 20080101

[Meta-analysis of phase III studies with palonosetron in the prevention of vomiting induced by moderately emetogenic chemotherapy].

Tumori 20080101

[Palonosetron in the prevention of chemotherapy-induced nausea and vomiting (CINV) in Italy: pharmacologic, clinical and economic aspects].

Tumori 20080101

Prophylactic antiemetic therapy for acute abdominal surgery. A comparative study of droperidol, metoclopramide, tropisetron, granisetron and dexamethasone.

Revista brasileira de anestesiologia 20080101

Acute selective serotonin reuptake inhibitors increase conditioned fear expression: blockade with a 5-HT(2C) receptor antagonist.

Biological psychiatry 20071115

Postoperative nausea, vomiting, airway morbidity, and analgesic requirements are lower for the ProSeal laryngeal mask airway than the tracheal tube in females undergoing breast and gynaecological surgery.

British journal of anaesthesia 20071001

A meta-analysis comparing the efficacy of four 5-HT3-receptor antagonists for acute chemotherapy-induced emesis.

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20070901

5-HT3 receptor antagonists regulate autonomic cardiac dysfunction in primary fibromyalgia syndrome.

Rheumatology international 20070901

[Prophylactic effect of tropisetron hydrochloride against nausea and vomiting in patients receiving chemotherapy for hematological malignancies].

Gan to kagaku ryoho. Cancer & chemotherapy 20070901

[Tropisetron hydrochloride in preventing and treating chemotherapy-induced nausea and vomiting: a phase II, randomized, multicenter, double-blinded, comparative clinical trial].

Ai zheng = Aizheng = Chinese journal of cancer 20070801

The reinforcing actions of a serotonin-3 receptor agonist within the ventral tegmental area: evidence for subregional and genetic differences and involvement of dopamine neurons.

The Journal of pharmacology and experimental therapeutics 20070601

Effects of medullary Raphé stimulation on fictive lung ventilation during development in Rana catesbeiana.

The Journal of experimental biology 20070601

Postoperative colonic motility after tropisetron and a standardized meal in patients undergoing conventional colorectal surgery.

International journal of colorectal disease 20070501

Randomized, double-blind trial comparing the antiemetic effect of tropisetron plus metopimazine with tropisetron plus placebo in patients receiving multiple cycles of multiple-day cisplatin-based chemotherapy.

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20070401

Determination of tropisetron in human plasma by high performance liquid chromatographic method with UV detection and its application to a bioequivalence study.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070201

Tropisetron modulation of the glycine receptor: femtomolar potentiation and a molecular determinant of inhibition.

Journal of neurochemistry 20070201

[A randomized double-blind study of prevention of postoperative nausea and vomiting with ondansetron, tropisetron, or granisetron in patients undergoing general anesthesia].

Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 20070201

Opposite effects of presynaptic 5-HT3 receptor activation on spontaneous and action potential-evoked GABA release at hippocampal synapses.

Journal of neurochemistry 20070101

In vitro pharmacological characterization of mitemcinal (GM-611), the first acid-resistant non-peptide motilin receptor agonist, in smooth muscle of rabbit small intestine.

Pharmacology 20070101

The efficacy of 5-HT3 receptor antagonists for the prevention of postoperative nausea and vomiting after craniotomy: a meta-analysis.

Journal of neurosurgical anesthesiology 20070101

Tropisetron, ondansetron, and granisetron for control of chemotherapy-induced emesis in Turkish cancer patients: a comparison of efficacy, side-effect profile, and cost.

Cancer investigation 20070101

Prevention of postoperative nausea and vomiting in children following adenotonsillectomy, using tropisetron with or without low-dose dexamethasone.

Journal of anesthesia 20070101

Phencyclidine-induced cognitive deficits in mice are improved by subsequent subchronic administration of tropisetron: role of alpha7 nicotinic receptors.

European journal of pharmacology 20061228

Contribution of peripheral 5-HT2A or 5-HT3 receptors to Fos expression in the trigeminal spinal nucleus produced by acute injury to the masseter muscle during persistent temporomandibular joint inflammation in rats.

Neuroscience 20061201

A randomized, placebo-controlled trial of a single dose of tropisetron for the prevention of vomiting after strabismus surgery in children.

The Mount Sinai journal of medicine, New York 20061201

Expression of heteromeric glycine receptor-channels in rat spinal cultures and inhibition by neuroactive steroids.

Neurochemistry international 20061101

[5-HT3 receptor antagonist als analgetics in rheumatic diseases].

Zeitschrift fur Rheumatologie 20061001

Acute treatment with 5-HT3 receptor antagonist, tropisetron, reduces immobility in intact female rats exposed to the forced swim test.

Pharmacology, biochemistry, and behavior 20061001

Tooth-pulp-evoked rostral spinal trigeminal neuronal excitation is attenuated by the activation of 5-HT3 receptors via GABAergic interneurons in the rat.

Brain research 20060913

Anti-emetic prophylaxis with oral tropisetron and/or dexamethasone.

European journal of clinical investigation 20060801

Effects of dexfenfluramine and 5-HT3 receptor antagonists on stress-induced reinstatement of alcohol seeking in rats.

Psychopharmacology 20060501

Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

The prevention of emergence agitation with tropisetron or clonidine after sevoflurane anesthesia in small children undergoing adenoidectomy.

Anesthesia and analgesia 20060501

Analgesic effect of acetaminophen in humans: first evidence of a central serotonergic mechanism.

Clinical pharmacology and therapeutics 20060401

Early vs late intraoperative administration of tropisetron for the prevention of nausea and vomiting in children undergoing tonsillectomy and/or adenoidectomy.

Paediatric anaesthesia 20060401

The effects of the prophylactic tropisetron-propofol combination on postoperative nausea and vomiting in patients undergoing thyroidectomy under desflurane anesthesia.

The Mount Sinai journal of medicine, New York 20060301

Ondansetron and tropisetron do not prevent intraspinal morphine- and fentanyl-induced pruritus in elective cesarean delivery.

Acta anaesthesiologica Scandinavica 20060201

Mode of action of gingerols and shogaols on 5-HT3 receptors: binding studies, cation uptake by the receptor channel and contraction of isolated guinea-pig ileum.

European journal of pharmacology 20060113

Supraventricular tachycardia and ST segment depression after intravenous administration of tropisetron.

European journal of anaesthesiology 20060101

Luminal hypotonicity increases duodenal mucosal permeability by a mechanism involving 5-hydroxytryptamine.

Acta physiologica (Oxford, England) 20060101

Prophylactic tropisetron versus rescue tropisetron in fractionated radiotherapy to moderate or high emetogenic areas: a prospective randomized open label study in cancer patients.

Medical oncology (Northwood, London, England) 20060101

Antinociception: mechanistic studies on the action of MD-354 and clonidine. Part 1. The 5-HT3 component.

European journal of pharmacology 20051228

Association of the ABCB1 3435C>T polymorphism with antiemetic efficacy of 5-hydroxytryptamine type 3 antagonists.

Clinical pharmacology and therapeutics 20051201

Tropisetron improves deficient inhibitory auditory processing in DBA/2 mice: role of alpha 7 nicotinic acetylcholine receptors.

Psychopharmacology 20051101

A nonneuronal 5-hydroxytryptamine receptor 3 induces chloride secretion in the rat distal colonic mucosa.

American journal of surgery 20051101

Mediation of neurogenic ion transport by acetylcholine, prostanoids and 5-hydroxytryptamine in porcine ileum.

European journal of pharmacology 20050920

The 5-HT3 receptor antagonist tropisetron inhibits T cell activation by targeting the calcineurin pathway.

Biochemical pharmacology 20050801

[Preventive efficacies of china-made tropisetron hydrochloride and Navoban on chemotherapy-induced nausea and vomiting: a randomized controlled clinical trial].

Ai zheng = Aizheng = Chinese journal of cancer 20050801

5HT3-receptor antagonists as antiemetics in cancer.

Drug and therapeutics bulletin 20050801

Update on anti-emetics for chemotherapy-induced emesis.

Internal medicine journal 20050801

Tropisetron: optimal dosage for children in prevention of chemotherapy-induced vomiting.

Pediatric blood & cancer 20050701

Tropisetron improves deficits in auditory P50 suppression in schizophrenia.

Schizophrenia research 20050701

Molecular dissection of tropisetron, an alpha7 nicotinic acetylcholine receptor-selective partial agonist.

Neuroscience letters 20050422

Intracranial self-administration of cocaine within the posterior ventral tegmental area of Wistar rats: evidence for involvement of serotonin-3 receptors and dopamine neurons.

The Journal of pharmacology and experimental therapeutics 20050401

Bradykinin potentiates 5-HT3 receptor-mediated current in rat trigeminal ganglion neurons.

Acta pharmacologica Sinica 20050401

Tooth-pulp-evoked rostral spinal trigeminal nucleus neuron activity is inhibited by conditioning sciatic nerve stimulation in the rat: possible role of 5-HT3 receptor mediated GABAergic inhibition.

Brain research bulletin 20050215

Regional heterogeneity for the intracranial self-administration of ethanol and acetaldehyde within the ventral tegmental area of alcohol-preferring (P) rats: involvement of dopamine and serotonin.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20050201

Serotonin type 3 receptors stimulate offensive aggression in Syrian hamsters.

Behavioural brain research 20050106

Peristalsis in the Guinea pig small intestine in vitro is impaired by acetaminophen but not aspirin and dipyrone.

Anesthesia and analgesia 20050101

Granisetron versus tropisetron for prophylaxis of acute chemotherapy-induced emesis: a pooled analysis.

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20050101

Central serotonin 3 receptors play an important role in the modulation of nociceptive neural activity of trigeminal subnucleus caudalis and nocifensive orofacial behavior in rats with persistent temporomandibular joint inflammation.

Neuroscience 20050101

The role of 5-hydroxytryptamine3 receptors in the vagal afferent activation-induced inhibition of the first cervical dorsal horn spinal neurons projected from tooth pulp in the rat.

The Journal of pharmacology and experimental therapeutics 20041101

Potentiation of 5-HT3 receptor function by the activation of coexistent 5-HT2 receptors in trigeminal ganglion neurons of rats.

Neuropharmacology 20041101

Activation of presynaptic 5-HT3 receptors facilitates glutamatergic synaptic inputs to area postrema neurons in rat brain slices.

Methods and findings in experimental and clinical pharmacology 20041001

Blockade of peripheral 5HT3 receptor attenuates the formalin-induced nocifensive behavior in persistent temporomandibular joint inflammation of rat.

Neuroscience letters 20040902

Acetaminophen: a central analgesic drug that involves a spinal tropisetron-sensitive, non-5-HT(3) receptor-mediated effect.

Molecular pharmacology 20040901

[Serotonin and anticancer drug-induced emesis].

Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20040801

5-HT3 antagonist ICS 205-930 enhances naltrexone's effects on ethanol intake.

European journal of pharmacology 20040503

5-HT receptors involved in opioid-activated descending inhibition of spinal withdrawal reflexes in the decerebrated rabbit.

Pain 20040501

Antipruritic effects of two different 5-HT3 receptor antagonists and an antihistamine in haemodialysis patients.

Experimental dermatology 20040501

Activity of alpha7-selective agonists at nicotinic and serotonin 5HT3 receptors expressed in Xenopus oocytes.

Bioorganic & medicinal chemistry letters 20040419

[Tropisetron in attenuation of nausea and vomiting in patients undergoing high-dose chemo-radiotherapy supported by autologous peripheral blood stem cell transplantation].

Ai zheng = Aizheng = Chinese journal of cancer 20040401

Patterns of serotonin- and 2-methylserotonin-induced pain may reflect 5-HT3 receptor sensitization.

European journal of pharmacology 20040112

Efficacy and tolerability of intravenous tropisetron in the treatment of fibromyalgia.

Scandinavian journal of rheumatology 20040101

The influence of the 5-HT3 receptor antagonist tropisetron on pain in fibromyalgia: a functional magnetic resonance imaging pilot study.