6-chloro-3-(dichloromethyl)-1,1-dioxo-3,4-dihydro-2H-1$l^{6},2,4-benzothiadiazine-7-sulfonamide
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Endothelin 1 activation of endothelin A receptor/NADPH oxidase pathway and diminished antioxidants critically contribute to endothelial progenitor cell reduction and dysfunction in salt-sensitive hypertension. | Hypertension (Dallas, Tex. : 1979) 20120501 |
A novel compound heterozygous mutation of Gitelman's syndrome in Japan, as diagnosed by an extraordinary response of the fractional excretion rate of chloride in the trichlormethiazide loading test. | Internal medicine (Tokyo, Japan) 20120101 |
Adverse effect profile of trichlormethiazide: a retrospective observational study. | Cardiovascular diabetology 20110101 |
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. | Bioorganic & medicinal chemistry letters 20101101 |
Combination therapy of calcium channel blocker and angiotensin II receptor blocker reduces augmentation index in hypertensive patients. | The American journal of the medical sciences 20100501 |
Piracetam defines a new binding site for allosteric modulators of alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA) receptors. | Journal of medicinal chemistry 20100311 |
Antioxidative effects of thiazide diuretics in refractory hypertensive patients. A randomized crossover trial of chlortalidone and trichlormethiazide. | Arzneimittel-Forschung 20100101 |
Evaluation of arterial stiffness in morning hypertension under high-dose valsartan compared to valsartan plus low-dose diuretic. | Hypertension research : official journal of the Japanese Society of Hypertension 20091201 |
Effect of pharmaceutical excipients on the stability of trichlormethiazide tablets under humid conditions. | Chemical & pharmaceutical bulletin 20091201 |
Angiotensin-II receptor antagonist combined with calcium channel blocker or diuretic for essential hypertension. | Hypertension research : official journal of the Japanese Society of Hypertension 20091101 |
Comparison of effects of low dose of spironolactone and a thiazide diuretic in patients with hypertension treated with an angiotensin-converting enzyme inhibitor or an angiotensin type 1 receptor blocker. | Clinical and experimental hypertension (New York, N.Y. : 1993) 20091101 |
Salt-losing nephrogenic diabetes insipidus caused by fetal exposure to angiotensin receptor blocker. | Pediatric nephrology (Berlin, Germany) 20090601 |
Carbonic anhydrase inhibitors. Comparison of chlorthalidone, indapamide, trichloromethiazide, and furosemide X-ray crystal structures in adducts with isozyme II, when several water molecules make the difference. | Bioorganic & medicinal chemistry 20090201 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. | Journal of medicinal chemistry 20081113 |
Effects of an ARB on endothelial progenitor cell function and cardiovascular oxidation in hypertension. | American journal of hypertension 20080101 |
TARP auxiliary subunits switch AMPA receptor antagonists into partial agonists. | Science (New York, N.Y.) 20071102 |
Carbonic anhydrase inhibitors: inhibition of human, bacterial, and archaeal isozymes with benzene-1,3-disulfonamides--solution and crystallographic studies. | Bioorganic & medicinal chemistry letters 20070801 |
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Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 |
Angiotensin II type 1 receptor blockers reduce urinary oxidative stress markers in hypertensive diabetic nephropathy. | Hypertension (Dallas, Tex. : 1979) 20060401 |
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Clinical characteristics of eight patients with congenital nephrogenic diabetes insipidus. | Endocrine 20040601 |
Change in the circadian rhythm of blood pressure in pseudo-hypoaldosteronism type 2 in response to thiazide diuretics. | Clinical nephrology 20040501 |
Upregulation of ligand, receptor system, and amidating activity of adrenomedullin in left ventricular hypertrophy of severely hypertensive rats: effects of angiotensin-converting enzyme inhibitors and diuretic. | Journal of hypertension 20030601 |
A case of exercise-induced acute renal failure in a patient with idiopathic renal hypouricemia developed during antihypertensive therapy with losartan and trichlormethiazide. | Hypertension research : official journal of the Japanese Society of Hypertension 20030601 |
Successful treatment of partial nephrogenic diabetes insipidus with thiazide and desmopressin. | Hormone research 20030101 |
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Influence of the angiotensin II receptor antagonist losartan on diuretic-induced metabolic effects in elderly hypertensive patients: comparison with a calcium channel blocker. | International journal of clinical pharmacology and therapeutics 20011001 |
Characterization of the antihypertensive effect of a thiazide diuretic in angiotensin II-induced hypertension. | Journal of hypertension 20010901 |
Tolerability and safety of a calcium channel blocker in comparison with a diuretic in the treatment of elderly patients with hypertension: secondary analysis of the NICS-EH. | Hypertension research : official journal of the Japanese Society of Hypertension 20010901 |
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds. | Journal of medicinal chemistry 20010719 |
Functional comparison of the K+-Cl- cotransporters KCC1 and KCC4. | The Journal of biological chemistry 20000929 |
Inhibition of human thiopurine methyltransferase by furosemide, bendroflumethiazide and trichlormethiazide. | European journal of clinical pharmacology 19960101 |
Protective effects of KW-3902, a novel adenosine A1-receptor antagonist, against gentamicin-induced acute renal failure in rats. | Japanese journal of pharmacology 19940601 |
Effects of KW-3902, a novel adenosine A1-receptor antagonist, on cephaloridine-induced acute renal failure in rats. | Japanese journal of pharmacology 19940101 |
Renal arteriolar diameters in spontaneously hypertensive rats. Vascular cast study. | Hypertension (Dallas, Tex. : 1979) 19910701 |
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Vasodilator effect of indapamide in dog mesenteric vasculature. | Japanese journal of pharmacology 19851101 |
Depression after treatment with thiazide diuretics for hypertension. | The American journal of psychiatry 19850901 |
Sinus arrest following diuretic therapy in a patient with myxedema and hypertension. | Cardiology 19750101 |