Terfenadine
| Title | Journal |
|---|---|
| Mechanism of As2O3-Induced Action Potential Prolongation and Using hiPS-CMs to Evaluate the Rescue Efficacy of Drugs With Different Rescue Mechanism. | Toxicological sciences : an official journal of the Society of Toxicology 20170801 |
| Observations on conducting whole-cell patch clamping of the hERG cardiac K(+) channel in pure human serum. | Journal of applied toxicology : JAT 20170401 |
| Why Can dl-Sotalol Prolong the QT Interval In Vivo Despite Its Weak Inhibitory Effect on hERG K(+) Channels In Vitro? Electrophysiological and Pharmacokinetic Analysis with the Halothane-Anesthetized Guinea Pig Model. | Cardiovascular toxicology 20160401 |
| H1-antihistamines exacerbate high-fat diet-induced hepatic steatosis in wild-type but not in apolipoprotein E knockout mice. | American journal of physiology. Gastrointestinal and liver physiology 20140715 |
| Availability of human induced pluripotent stem cell-derived cardiomyocytes in assessment of drug potential for QT prolongation. | Toxicology and applied pharmacology 20140701 |
| Chronic ingestion of H1-antihistamines increase progression of atherosclerosis in apolipoprotein E-/- mice. | PloS one 20140101 |
| Early identification of clinically relevant drug interactions with the human bile salt export pump (BSEP/ABCB11). | Toxicological sciences : an official journal of the Society of Toxicology 20131201 |
| Activity, inhibition, and induction of cytochrome P450 2J2 in adult human primary cardiomyocytes. | Drug metabolism and disposition: the biological fate of chemicals 20131201 |
| Refining the human iPSC-cardiomyocyte arrhythmic risk assessment model. | Toxicological sciences : an official journal of the Society of Toxicology 20131201 |
| Validation of visualized transgenic zebrafish as a high throughput model to assay bradycardia related cardio toxicity risk candidates. | Journal of applied toxicology : JAT 20121001 |
| Involvement of serine protease and proteinase-activated receptor 2 in dermatophyte-associated itch in mice. | The Journal of pharmacology and experimental therapeutics 20121001 |
| H(1)-antihistamines and urticaria: how can we predict the best drug for our patient? | Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20121001 |
| Negative electro-mechanical windows are required for drug-induced Torsades de Pointes in the anesthetized guinea pig. | Journal of pharmacological and toxicological methods 20120901 |
| Effect of intestinal first-pass hydrolysis on the oral bioavailability of an ester prodrug of fexofenadine. | Journal of pharmaceutical sciences 20120901 |
| Synthesis of betulinic acid derivatives as entry inhibitors against HIV-1 and bevirimat-resistant HIV-1 variants. | Bioorganic & medicinal chemistry letters 20120815 |
| Optimization of 4-aminoquinoline/clotrimazole-based hybrid antimalarials: further structure-activity relationships, in vivo studies, and preliminary toxicity profiling. | Journal of medicinal chemistry 20120809 |
| Quantification of fexofenadine in biological matrices: a review of bioanalytical methods. | Biomedical chromatography : BMC 20120801 |
| Exploring novel colon-targeting antihistaminic prodrug for colitis. | Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20120801 |
| Cathepsin E induces itch-related response through the production of endothelin-1 in mice. | European journal of pharmacology 20120705 |
| Microdosing clinical study: pharmacokinetic, pharmacogenomic (SLCO2B1), and interaction (grapefruit juice) profiles of celiprolol following the oral microdose and therapeutic dose. | Journal of clinical pharmacology 20120701 |
| Mouse model of touch-evoked itch (alloknesis). | The Journal of investigative dermatology 20120701 |
| Development of recombinant cell line co-expressing mutated Nav1.5, Kir2.1, and hERG for the safety assay of drug candidates. | Journal of biomolecular screening 20120701 |
| Enhanced systemic exposure of fexofenadine via the intranasal administration of chitosan-coated liposome. | International journal of pharmaceutics 20120701 |
| Long-lasting inhibition of the intestinal absorption of fexofenadine by cyclosporin A in rats. | Journal of pharmaceutical sciences 20120701 |
| Influence of Panax ginseng on cytochrome P450 (CYP)3A and P-glycoprotein (P-gp) activity in healthy participants. | Journal of clinical pharmacology 20120601 |
| The impact of P-glycoprotein mediated efflux on absorption of 11 sedating and less-sedating antihistamines using Caco-2 monolayers. | Xenobiotica; the fate of foreign compounds in biological systems 20120601 |
| Does terfenadine-induced ventricular tachycardia/fibrillation directly relate to its QT prolongation and Torsades de Pointes? | British journal of pharmacology 20120601 |
| An overview of bilastine metabolism during preclinical investigations. | Drug and chemical toxicology 20120601 |
| Whole-cell configuration of the patch-clamp technique in the hERG channel assay to predict the ability of a compound to prolong QT interval. | Current protocols in pharmacology 20120601 |
| Enhancement of clara cell 10-kD protein (CC10) production from nasal epithelial cells by fexofenadine hydrochloride. | Asian Pacific journal of allergy and immunology 20120601 |
| Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. | Journal of medicinal chemistry 20120524 |
| The electro-mechanical window in anaesthetized guinea pigs: a new marker in screening for Torsade de Pointes risk. | British journal of pharmacology 20120501 |
| Intestinal OATP1A2 inhibition as a potential mechanism for the effect of grapefruit juice on aliskiren pharmacokinetics in healthy subjects. | European journal of clinical pharmacology 20120501 |
| Effects of single therapeutic doses of promethazine, fexofenadine and olopatadine on psychomotor function and histamine-induced wheal- and flare-responses: a randomized double-blind, placebo-controlled study in healthy volunteers. | Archives of dermatological research 20120501 |
| Identifying a selective substrate and inhibitor pair for the evaluation of CYP2J2 activity. | Drug metabolism and disposition: the biological fate of chemicals 20120501 |
| Involvement of leukotriene B4 in itching in a mouse model of ocular allergy. | Experimental eye research 20120501 |
| Characterization of A-935142, a hERG enhancer, in the presence and absence of standard hERG blockers. | Life sciences 20120420 |
| Preseasonal prophylactic treatment with antihistamines suppresses IL-5 but not IL-33 mRNA expression in the nasal mucosa of patients with seasonal allergic rhinitis caused by Japanese cedar pollen. | Acta oto-laryngologica 20120401 |
| Different effects of the selective serotonin reuptake inhibitors fluvoxamine, paroxetine, and sertraline on the pharmacokinetics of fexofenadine in healthy volunteers. | Journal of clinical psychopharmacology 20120401 |
| Structure determination of fexofenadine-α-cyclodextrin complex by quantitative 2D ROESY analysis and molecular mechanics studies. | Magnetic resonance in chemistry : MRC 20120401 |
| In vitro-in situ permeability and dissolution of fexofenadine with kinetic modeling in the presence of sodium dodecyl sulfate. | European journal of drug metabolism and pharmacokinetics 20120301 |
| Carbamazepine differentially affects the pharmacokinetics of fexofenadine enantiomers. | British journal of clinical pharmacology 20120301 |
| A randomized control trail of stepwise treatment with fluticasone propionate nasal spray and fexofenadine hydrochloride tablet for seasonal allergic rhinitis. | Allergology international : official journal of the Japanese Society of Allergology 20120301 |
| Pharmacophore modeling for hERG channel facilitation. | Biochemical and biophysical research communications 20120203 |
| Inhibition of HERG1 K+ channel protein expression decreases cell proliferation of human small cell lung cancer cells. | Pflugers Archiv : European journal of physiology 20120201 |
| The effects of an H3 receptor antagonist (PF-03654746) with fexofenadine on reducing allergic rhinitis symptoms. | The Journal of allergy and clinical immunology 20120201 |
| Ketoconazole-associated preferential increase in dopamine D2 receptor occupancy in striatum compared to pituitary in vivo: role for drug transporters? | Journal of clinical psychopharmacology 20120201 |
| Treatment of acquired perforating dermatosis with cantharidin. | Archives of dermatology 20120201 |
| Salinomycin inhibits prostate cancer growth and migration via induction of oxidative stress. | British journal of cancer 20120103 |
| Noninvasive evaluation of contractile behavior of cardiomyocyte monolayers based on motion vector analysis. | Tissue engineering. Part C, Methods 20120101 |
| Spectrofluorimetric determination of etodolac, moxepril HCl and fexofenadine HCl using europium sensitized fluorescence in bulk and pharmaceutical preparations. | Journal of fluorescence 20120101 |
| Effects of bepotastine and fexofenadine on histamine-induced flare, wheal and itch. | International archives of allergy and immunology 20120101 |
| The PI3-kinase/mTOR-targeting drug NVP-BEZ235 inhibits growth and IgE-dependent activation of human mast cells and basophils. | PloS one 20120101 |
| Toward a New Gold Standard for Early Safety: Automated Temperature-Controlled hERG Test on the PatchLiner. | Frontiers in pharmacology 20120101 |
| Incidence and risk of QTc interval prolongation among cancer patients treated with vandetanib: a systematic review and meta-analysis. | PloS one 20120101 |
| Histamine H1 antagonists and clinical characteristics of febrile seizures. | International journal of general medicine 20120101 |
| Adaptation and validation of the Urticaria Patient Daily Diary for adolescents. | Allergy and asthma proceedings 20120101 |
| Phenytoin in treatment of amiodarone-induced Torsades de pointes. | Indian journal of pharmacology 20120101 |
| Spectrophotometric Determination of Mycophenolate Mofetil as Its Charge-Transfer Complexes with Two π-Acceptors. | Journal of analytical methods in chemistry 20120101 |
| Mechanisms, risk factors, and management of acquired long QT syndrome: a comprehensive review. | TheScientificWorldJournal 20120101 |
| In vitro model for assessing arrhythmogenic properties of drugs based on high-resolution impedance measurements. | Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20120101 |
| Development and validation of an automated high-throughput system for zebrafish in vivo screenings. | PloS one 20120101 |
| Drug discovery models and toxicity testing using embryonic and induced pluripotent stem-cell-derived cardiac and neuronal cells. | Stem cells international 20120101 |
| Triarylmethanes, a new class of cx50 inhibitors. | Frontiers in pharmacology 20120101 |
| The effect of antihistamines on seizures induced by increasing-current electroshocks: ketotifen, but not olopatadine, promotes the seizures in infant rats. | Biological & pharmaceutical bulletin 20120101 |
| Development of a highly sensitive methodology for quantitative determination of fexofenadine in a microdose study by multiple injection method using ultra-high performance liquid chromatography with tandem mass spectrometry. | Biological & pharmaceutical bulletin 20120101 |
| Comparison of nasal steroid with antihistamine in prophylactic treatment against pollinosis using an environmental challenge chamber. | Allergy and asthma proceedings 20120101 |
| Optimization using central composite design for antihistamines separation by nonaqueous capillary electrophoresis with electrochemical and electrochemiluminescence detections. | The Analyst 20111221 |
| Liquid extraction surface analysis mass spectrometry (LESA-MS) as a novel profiling tool for drug distribution and metabolism analysis: the terfenadine example. | Rapid communications in mass spectrometry : RCM 20111215 |
| Introduction of a modular automated voltage-clamp platform and its correlation with manual human Ether-à-go-go related gene voltage-clamp data. | Assay and drug development technologies 20111201 |
| Terfenadine induces apoptosis and autophagy in melanoma cells through ROS-dependent and -independent mechanisms. | Apoptosis : an international journal on programmed cell death 20111201 |
| Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). | PLoS computational biology 20111201 |
| Fexofenadine-induced urticaria. | Annals of dermatology 20111201 |
| Estimation of P-glycoprotein-mediated efflux in the oral absorption of P-gp substrate drugs from simultaneous analysis of drug dissolution and permeation. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20111120 |
| Ameliorating effect of Yokukansan on the development of atopic dermatitis-like lesions and scratching behavior in socially isolated NC/Nga mice. | Archives of dermatological research 20111101 |
| Vectorial transport of fexofenadine across Caco-2 cells: involvement of apical uptake and basolateral efflux transporters. | Molecular pharmaceutics 20111003 |
| Evaluation of the genotoxicity and cytotoxicity of fexofenadine in cultured human peripheral blood lymphocytes. | Toxicology in vitro : an international journal published in association with BIBRA 20111001 |
| Simultaneous UFLC-ESI-MS/MS determination of piperine and piperlonguminine in rat plasma after oral administration of alkaloids from Piper longum L.: application to pharmacokinetic studies in rats. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20111001 |
| Assessment of fexofenadine hydrochloride permeability and dissolution with an anionic surfactant using Caco-2 cells. | Die Pharmazie 20111001 |
| Validation of membrane vesicle-based breast cancer resistance protein and multidrug resistance protein 2 assays to assess drug transport and the potential for drug-drug interaction to support regulatory submissions. | Xenobiotica; the fate of foreign compounds in biological systems 20110901 |
| Physiologically based pharmacokinetic modeling of intestinal first-pass metabolism of CYP3A substrates with high intestinal extraction. | Drug metabolism and disposition: the biological fate of chemicals 20110901 |
| Estimating the risk of drug-induced proarrhythmia using human induced pluripotent stem cell-derived cardiomyocytes. | Toxicological sciences : an official journal of the Society of Toxicology 20110901 |
| Atypical antipsychotics and effects of muscarinic, serotonergic, dopaminergic and histaminergic receptor binding on insulin secretion in vivo: an animal model. | Schizophrenia research 20110901 |
| Quantification of the transporter substrate fexofenadine in cell lysates by liquid chromatography/tandem mass spectrometry. | Rapid communications in mass spectrometry : RCM 20110830 |
| Histaminergic modulation of acetylcholine-induced γ oscillations in rat hippocampus. | Neuroreport 20110803 |
| Block of the hERG channel by bupivacaine: Electrophysiological and modeling insights towards stereochemical optimization. | European journal of medicinal chemistry 20110801 |
| The biological basis and clinical significance of hormonal imprinting, an epigenetic process. | Clinical epigenetics 20110801 |
| Buspirone, fexofenadine, and omeprazole: quantification of probe drugs and their metabolites in human plasma. | Journal of pharmaceutical and biomedical analysis 20110715 |
| Simulation of multiple ion channel block provides improved early prediction of compounds' clinical torsadogenic risk. | Cardiovascular research 20110701 |
| Species differences in intestinal metabolic activities of cytochrome P450 isoforms between cynomolgus monkeys and humans. | Drug metabolism and pharmacokinetics 20110601 |
| In brief: fexofenadine (Allegra) and fruit juice. | The Medical letter on drugs and therapeutics 20110530 |
| Drug-induced QTC prolongation dangerously underestimates proarrhythmic potential: lessons from terfenadine. | Journal of cardiovascular pharmacology 20110501 |
| A new cytochrome P450 belonging to the 107L subfamily is responsible for the efficient hydroxylation of the drug terfenadine by Streptomyces platensis. | Archives of biochemistry and biophysics 20110401 |
| Transcriptional repression of the M channel subunit Kv7.2 in chronic nerve injury. | Pain 20110401 |
| Drug evaluation in cardiomyocytes derived from human induced pluripotent stem cells carrying a long QT syndrome type 2 mutation. | European heart journal 20110401 |
| Potent farnesyltransferase inhibitors with 1,4-diazepane scaffolds as novel destabilizing microtubule agents in hormone-resistant prostate cancer. | Journal of medicinal chemistry 20110310 |
| Analysis of Relationship between Levofloxacin and Corrected QT Prolongation Using a Clinical Data Warehouse. | Healthcare informatics research 20110301 |
| Poloxamer/cyclodextrin/chitosan-based thermoreversible gel for intranasal delivery of fexofenadine hydrochloride. | Journal of pharmaceutical sciences 20110201 |
| Roles of affinity and lipophilicity in the slow kinetics of prostanoid receptor antagonists on isolated smooth muscle preparations. | British journal of pharmacology 20110201 |
| Present state and future perspectives of using pluripotent stem cells in toxicology research. | Archives of toxicology 20110201 |
| The effects of the SLCO2B1 c.1457C > T polymorphism and apple juice on the pharmacokinetics of fexofenadine and midazolam in humans. | Pharmacogenetics and genomics 20110201 |
| Effect of histamine H1 receptor antagonists on TARC/CCL17 and MDC/CCL22 production from CD14+ cells induced by antigenic stimulation in vitro. | International archives of allergy and immunology 20110101 |
| Developmental changes in action potential prolongation by K+-channel blockers in chick myocardium. | Journal of pharmacological sciences 20110101 |
| The effect of histamine on ciliary beat frequency in the acute phase of allergic rhinitis. | American journal of otolaryngology 20110101 |
| Intranasal phototherapy is more effective than fexofenadine hydrochloride in the treatment of seasonal allergic rhinitis: results of a pilot study. | Photochemistry and photobiology 20110101 |
| Urticaria due to antihistamines. | Journal of investigational allergology & clinical immunology 20110101 |
| Validated stability-indicating spectrofluorimetric methods for the determination of ebastine in pharmaceutical preparations. | Chemistry Central journal 20110101 |
| A pseudo-randomised clinical trial of in situ gels of fluconazole for the treatment of oropharngeal candidiasis. | Trials 20110101 |
| Analysis of fexofenadine in pharmaceutical formulations using tris(1,10-phenanthroline)-ruthenium(II) peroxydisulphate chemiluminescence system in a multichip device. | Luminescence : the journal of biological and chemical luminescence 20110101 |
| Predicting drug side-effect profiles: a chemical fragment-based approach. | BMC bioinformatics 20110101 |
| hERGAPDbase: a database documenting hERG channel inhibitory potentials and APD-prolongation activities of chemical compounds. | Database : the journal of biological databases and curation 20110101 |
| A novel study design for antibiotic trials in acute exacerbations of COPD: MAESTRAL methodology. | International journal of chronic obstructive pulmonary disease 20110101 |
| Cardiac arrest provoked by itraconazole and amiodarone interaction: a case report. | Journal of medical case reports 20110101 |
| Development of a novel high-throughput analytical methodology, multiple injection method, for quantitative analysis in drug metabolism and pharmacokinetic studies using liquid chromatography with tandem mass spectrometry. | Biological & pharmaceutical bulletin 20110101 |
| Improvement of effect of water-in-oil microemulsion as an oral delivery system for fexofenadine: in vitro and in vivo studies. | International journal of nanomedicine 20110101 |
| IL-4 amplifies the pro-inflammatory effect of adenosine in human mast cells by changing expression levels of adenosine receptors. | PloS one 20110101 |
| Systematic review on the efficacy of fexofenadine in seasonal allergic rhinitis: a meta-analysis of randomized, double-blind, placebo-controlled clinical trials. | International archives of allergy and immunology 20110101 |
| Cough management: a practical approach. | Cough (London, England) 20110101 |
| Electrophysiological characterization of cardiomyocytes derived from human induced pluripotent stem cells. | Journal of pharmacological sciences 20110101 |
| Inhibition of HERG potassium channels by celecoxib and its mechanism. | PloS one 20110101 |
| Ebastine in chronic spontaneous urticaria in higher doses. | Indian journal of dermatology 20110101 |
| Substitute of Animals in Drug Research: An Approach Towards Fulfillment of 4R's. | Indian journal of pharmaceutical sciences 20110101 |
| Development of validated stability-indicating chromatographic method for the determination of fexofenadine hydrochloride and its related impurities in pharmaceutical tablets. | Chemistry Central journal 20110101 |
| In silico analysis of conformational changes induced by mutation of aromatic binding residues: consequences for drug binding in the hERG K+ channel. | PloS one 20110101 |
| Regional absorption of fexofenadine in rat intestine. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20101223 |
| 20(S)-ginsenoside Rh2 noncompetitively inhibits P-glycoprotein in vitro and in vivo: a case for herb-drug interactions. | Drug metabolism and disposition: the biological fate of chemicals 20101201 |
| A predictive ligand-based Bayesian model for human drug-induced liver injury. | Drug metabolism and disposition: the biological fate of chemicals 20101201 |
| CYP3A4*16 and CYP3A4*18 alleles found in East Asians exhibit differential catalytic activities for seven CYP3A4 substrate drugs. | Drug metabolism and disposition: the biological fate of chemicals 20101201 |
| Cytochrome P450-derived eicosanoids: the neglected pathway in cancer. | Cancer metastasis reviews 20101201 |
| Identification of human Ether-à-go-go related gene modulators by three screening platforms in an academic drug-discovery setting. | Assay and drug development technologies 20101201 |
| Monensin is a potent inducer of oxidative stress and inhibitor of androgen signaling leading to apoptosis in prostate cancer cells. | Molecular cancer therapeutics 20101201 |
| QTc interval prolongation by fexofenadine in healthy human volunteers and its correlation with plasma levels of fexofenadine: A demonstration of anticlockwise hysteresis. | Indian journal of pharmacology 20101201 |
| Development of a list of potentially inappropriate drugs for the korean elderly using the delphi method. | Healthcare informatics research 20101201 |
| Influence of drug-transporter polymorphisms on the pharmacokinetics of fexofenadine enantiomers. | Xenobiotica; the fate of foreign compounds in biological systems 20101101 |
| Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. | Bioorganic & medicinal chemistry letters 20101101 |
| Pharmacokinetics of fexofenadine following LPS administration to rats. | Xenobiotica; the fate of foreign compounds in biological systems 20101101 |
| Fruit juice inhibition of uptake transport: a new type of food-drug interaction. | British journal of clinical pharmacology 20101101 |
| H1-receptor antagonists terfenadine and loratadine inhibit spontaneous growth of neoplastic mast cells. | Experimental hematology 20101001 |
| The relationship between the drug concentration profiles in plasma and the drug doses in the colon. | Chemical & pharmaceutical bulletin 20101001 |
| Induction of inflammatory cell accumulation by TM-N49 and promutoxin, two novel phospholipase A(2). | Toxicon : official journal of the International Society on Toxinology 20100915 |
| Discovering drug-drug interactions: a text-mining and reasoning approach based on properties of drug metabolism. | Bioinformatics (Oxford, England) 20100915 |
| Efficacy of leukotriene antagonists as concomitant therapy in allergic rhinitis. | The Laryngoscope 20100901 |
| A quantitative structure-activity relationship for the modulation effects of flavonoids on p-glycoprotein-mediated transport. | Chemical & pharmaceutical bulletin 20100901 |
| Oral bepotastine: in allergic disorders. | Drugs 20100820 |
| Preparation and evaluation of fexofenadine microemulsions for intranasal delivery. | International journal of pharmaceutics 20100816 |
| Organic anion transporting polypeptide 1a/1b-knockout mice provide insights into hepatic handling of bilirubin, bile acids, and drugs. | The Journal of clinical investigation 20100802 |
| LuxR-dependent quorum sensing: computer aided discovery of new inhibitors structurally unrelated to N-acylhomoserine lactones. | Bioorganic & medicinal chemistry letters 20100801 |
| Effect of metronidazole on the pharmacokinetics of fexofenadine, a P-glycoprotein substrate, in healthy male volunteers. | European journal of clinical pharmacology 20100701 |
| Multivariate data analysis of factors affecting the in vitro dissolution rate and the apparent solubility for a model basic drug substance in aqueous media. | Pharmaceutical research 20100701 |
| [Normal tissue tolerance to external beam radiation therapy: esophagus]. | Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique 20100701 |
| Histamine and histamine receptor antagonists in cancer biology. | Inflammation & allergy drug targets 20100701 |
| Effects of K openers on the QT prolongation induced by HERG-blocking drugs in guinea-pigs. | The Journal of pharmacy and pharmacology 20100701 |
| Arrhythmic risk biomarkers for the assessment of drug cardiotoxicity: from experiments to computer simulations. | Philosophical transactions. Series A, Mathematical, physical, and engineering sciences 20100628 |
| Melt-in-mouth pellets of fexofenadine hydrochloride using crospovidone as an extrusion-spheronisation aid. | AAPS PharmSciTech 20100601 |
| Pharmacokinetics of fexofenadine: evaluation of a microdose and assessment of absolute oral bioavailability. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20100512 |
| The effects of bilastine compared with cetirizine, fexofenadine, and placebo on allergen-induced nasal and ocular symptoms in patients exposed to aeroallergen in the Vienna Challenge Chamber. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20100501 |
| Preparation and evaluation of spray-dried hyaluronic acid microspheres for intranasal delivery of fexofenadine hydrochloride. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20100416 |
| Induction of microvascular leakage and histamine release by promutoxin, an Arg49 phospholipase A2. | Toxicon : official journal of the International Society on Toxinology 20100401 |
| Altered cytosolic Ca2+ dynamics in cultured Guinea pig cardiomyocytes as an in vitro model to identify potential cardiotoxicants. | Toxicology in vitro : an international journal published in association with BIBRA 20100401 |
| Interactions at human ether-à-go-go-related gene channels. | Toxicological sciences : an official journal of the Society of Toxicology 20100401 |
| Evaluation of in vivo P-glycoprotein phenotyping probes: a need for validation. | Clinical pharmacokinetics 20100401 |
| Direct analysis of dried blood spots utilizing desorption electrospray ionization (DESI) mass spectrometry. | The Analyst 20100401 |
| The pathophysiology, diagnosis and treatment of allergic rhinitis. | Allergy, asthma & immunology research 20100401 |
| Microdose study of a P-glycoprotein substrate, fexofenadine, using a non-radioisotope-labelled drug and LC/MS/MS. | Journal of clinical pharmacy and therapeutics 20100401 |
| Effect of piperine, a major component of black pepper, on the intestinal absorption of fexofenadine and its implication on food-drug interaction. | Journal of food science 20100401 |
| Measurement of fexofenadine concentration in micro-sample human plasma by a rapid and sensitive LC-MS/MS employing protein precipitation: application to a clinical pharmacokinetic study. | Biomedical chromatography : BMC 20100301 |
| Teriparatide is safe and effectively increases bone biomarkers in institutionalized individuals with osteoporosis. | Journal of bone and mineral metabolism 20100301 |
| Histamine influence on apoptosis in trophoblast cell cultures. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20100301 |
| Toward a consensus model of the HERG potassium channel. | ChemMedChem 20100301 |
| Development of a novel system for estimating human intestinal absorption using Caco-2 cells in the absence of esterase activity. | Drug metabolism and disposition: the biological fate of chemicals 20100201 |
| Identification of novel substrates for human cytochrome P450 2J2. | Drug metabolism and disposition: the biological fate of chemicals 20100201 |
| Validation and application of a liquid chromatography-tandem mass spectrometric method for quantification of the drug transport probe fexofenadine in human plasma using 96-well filter plates. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100201 |
| Evaluation and performance of desorption electrospray ionization using a triple quadrupole mass spectrometer for quantitation of pharmaceuticals in plasma. | Rapid communications in mass spectrometry : RCM 20100201 |
| Building a tiered approach to in vitro predictive toxicity screening: a focus on assays with in vivo relevance. | Combinatorial chemistry & high throughput screening 20100201 |
| Loratadine versus levocetirizine in chronic idiopathic urticaria: A comparative study of efficacy and safety. | Indian journal of pharmacology 20100201 |
| Dog left ventricular midmyocardial myocytes for assessment of drug-induced delayed repolarization: short-term variability and proarrhythmic potential. | British journal of pharmacology 20100101 |
| Characterization of anti-inflammatory properties and evidence for no sedation liability for the novel antihistamine SUN-1334H. | International archives of allergy and immunology 20100101 |
| Update on the evaluation of a new drug for effects on cardiac repolarization in humans: issues in early drug development. | British journal of pharmacology 20100101 |
| Clinical pharmacokinetics of fexofenadine enantiomers. | Expert opinion on drug metabolism & toxicology 20100101 |
| Development of an in silico model for human skin permeation based on a Franz cell skin permeability assay. | Bioorganic & medicinal chemistry letters 20100101 |
| [Administration of premedication with fexofenadine for paclitaxel-induced hypersensitive reactions in breast cancer patients complicated with closed-angle glaucoma]. | Gan to kagaku ryoho. Cancer & chemotherapy 20100101 |
| The action potential and comparative pharmacology of stem cell-derived human cardiomyocytes. | Journal of pharmacological and toxicological methods 20100101 |
| Interferences of the autonomic nervous system with drug induced QT prolongation: a point to consider in non-clinical safety studies. | Journal of pharmacological and toxicological methods 20100101 |
| Uni- or bi-ventricular hypertrophy and susceptibility to drug-induced torsades de pointes. | Journal of pharmacological and toxicological methods 20100101 |
| Treatment of congestion in upper respiratory diseases. | International journal of general medicine 20100101 |
| Rhinitis in the geriatric population. | Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology 20100101 |
| Simultaneous determination of gliquidone, fexofenadine, buclizine, and levocetirizine in dosage formulation and human serum by RP-HPLC. | Journal of chromatographic science 20100101 |
| Preparation and evaluation of transdermal plasters containing norfloxacin: a novel treatment for burn wound healing. | Eplasty 20100101 |
| Reproducibility of the airway response to an exercise protocol standardized for intensity, duration, and inspired air conditions, in subjects with symptoms suggestive of asthma. | Respiratory research 20100101 |
| Azelastine hydrochloride, a dual-acting anti-inflammatory ophthalmic solution, for treatment of allergic conjunctivitis. | Clinical ophthalmology (Auckland, N.Z.) 20100101 |
| Emerging treatments in the management of schizophrenia - focus on sertindole. | Drug design, development and therapy 20100101 |
| Evaluation of terfenadine and ketoconazole-induced QT prolongation in conscious telemetered guinea pigs. | Pharmacological reports : PR 20100101 |
| Inhibitory effects of the methanol extract of Ganoderma lucidum on mosquito allergy-induced itch-associated responses in mice. | Journal of pharmacological sciences 20100101 |
| Fosaprepitant and aprepitant: an update of the evidence for their place in the prevention of chemotherapy-induced nausea and vomiting. | Core evidence 20100101 |
| Effects of anti-malarial drugs on the electrocardiographic QT interval modelled in the isolated perfused guinea pig heart system. | Malaria journal 20100101 |
| Development, clinical utility, and place in therapy of posaconazole for prevention and treatment of invasive fungal infections. | Drug design, development and therapy 20100101 |
| Stereoselective block of hERG channel by bupivacaine scrutinized at molecular level. | Chimia 20100101 |
| Study of the Complexation Behaviour of Fexofenadine with β-Cyclodextrin. | Indian journal of pharmaceutical sciences 20100101 |
| Clinical utility and patient adherence with ebastine for allergic rhinitis. | Patient preference and adherence 20100101 |
| Management of tinea capitis in childhood. | Clinical, cosmetic and investigational dermatology 20100101 |
| Update on the management of chronic eczema: new approaches and emerging treatment options. | Clinical, cosmetic and investigational dermatology 20100101 |
| Clinical safety and tolerability issues in use of triazole derivatives in management of fungal infections. | Drug, healthcare and patient safety 20100101 |
| Natural product taking its own place!!! | Pharmacognosy research 20100101 |
| Stereoselective Inhibition of the hERG1 Potassium Channel. | Frontiers in pharmacology 20100101 |
| Long-term treatment of patients with HIV-1: the role of atazanavir. | HIV/AIDS (Auckland, N.Z.) 20100101 |
| N-(3,4-dimethoxyphenethyl)-4-(6,7-dimethoxy-3,4-dihydroisoquinolin-2[1H]-yl)-6,7-dimethoxyquinazolin-2-amine (CP-100,356) as a 'chemical knock-out equivalent' to assess the impact of efflux transporters on oral drug absorption in the rat. | Journal of pharmaceutical sciences 20091201 |
| Leukotriene B(4) mediates sphingosylphosphorylcholine-induced itch-associated responses in mouse skin. | The Journal of investigative dermatology 20091201 |
| Genetic deficiency of carnitine/organic cation transporter 2 (slc22a5) is associated with altered tissue distribution of its substrate pyrilamine in mice. | Biopharmaceutics & drug disposition 20091201 |
| Effects of the P-glycoprotein inducer carbamazepine on fexofenadine pharmacokinetics. | Therapeutic drug monitoring 20091201 |
| Inhibition of the human ether-a-go-go-related gene (HERG) K+ channels by Lindera erythrocarpa. | Journal of Korean medical science 20091201 |
| Assessment of the antiobstructive effect of fexofenadine on nasal allergy challenge in patients with seasonal allergic rhinitis. | Asian Pacific journal of allergy and immunology 20091201 |
| A new homogeneous high-throughput screening assay for profiling compound activity on the human ether-a-go-go-related gene channel. | Analytical biochemistry 20091101 |
| Leukotriene receptor antagonist in the treatment of childhood allergic rhinitis--a randomized placebo-controlled study. | Pediatric pulmonology 20091101 |
| Efavirenz: a decade of clinical experience in the treatment of HIV. | The Journal of antimicrobial chemotherapy 20091101 |
| ESRD impairs nonrenal clearance of fexofenadine but not midazolam. | Journal of the American Society of Nephrology : JASN 20091001 |
| Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum. | Nature chemical biology 20091001 |
| Comparing the stimulant effects of the H1-antagonist fexofenadine with 2 psychostimulants, modafinil and methylphenidate. | Journal of clinical psychopharmacology 20091001 |
| Allergen-induced airway inflammation and its therapeutic intervention. | Allergy, asthma & immunology research 20091001 |
| Unintended consequences of reducing QT-alert overload in a computerized physician order entry system. | European journal of clinical pharmacology 20090901 |
| Structural determinants for histamine H(1) affinity, hERG affinity and QTc prolongation in a series of terfenadine analogs. | Bioorganic & medicinal chemistry letters 20090901 |
| Effects of 4-Aminopyridine on Cloned hERG Channels Expressed in Mammalian Cells. | Archives of drug information 20090901 |
| Integration of preclinical and clinical data with pharmacokinetic modeling and simulation to evaluate fexofenadine as a probe for hepatobiliary transport function. | Pharmaceutical research 20090801 |
| Ureteral stones due to systemic mastocytosis: diagnostic and therapeutic characteristics. | Urological research 20090801 |
| Effect of St John's wort on the disposition of fexofenadine in the isolated perfused rat liver. | The Journal of pharmacy and pharmacology 20090801 |
| Iatrogenic QT Abnormalities and Fatal Arrhythmias: Mechanisms and Clinical Significance. | Current cardiology reviews 20090801 |
| Side chain flexibilities in the human ether-a-go-go related gene potassium channel (hERG) together with matched-pair binding studies suggest a new binding mode for channel blockers. | Journal of medicinal chemistry 20090723 |
| Fexofenadine: biochemical, pharmacokinetic and pharmacodynamic properties and its unique role in allergic disorders. | Expert opinion on drug metabolism & toxicology 20090701 |
| Allergies in India: a study on medication compliance. | Journal of the Indian Medical Association 20090701 |
| Pharmacokinetic drug interaction between fexofenadine and fluvastatin mediated by organic anion-transporting polypeptides in rats. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20090628 |
| Ether-à-gogo-related gene (erg1) potassium channels shape the dark response of horizontal cells in the mammalian retina. | Pflugers Archiv : European journal of physiology 20090601 |
| Short-term effect of quercetin on the pharmacokinetics of fexofenadine, a substrate of P-glycoprotein, in healthy volunteers. | European journal of clinical pharmacology 20090601 |
| Selective inhibitors of CYP2J2 related to terfenadine exhibit strong activity against human cancers in vitro and in vivo. | The Journal of pharmacology and experimental therapeutics 20090601 |
| Ligand diversity of human and chimpanzee CYP3A4: activation of human CYP3A4 by lithocholic acid results from positive selection. | Drug metabolism and disposition: the biological fate of chemicals 20090601 |
| Ether-à-go-go-related gene K+ channels contribute to threshold excitability of mouse auditory brainstem neurons. | The Journal of physiology 20090601 |
| Effects of pranlukast hydrate on airway hyperresponsiveness in non-asthmatic patients with Japanese cedar pollinosis. | Allergology international : official journal of the Japanese Society of Allergology 20090601 |
| Fexofenadine hydrochloride enhances the efficacy of contact immunotherapy for extensive alopecia areata: Retrospective analysis of 121 cases. | The Journal of dermatology 20090601 |
| Suppression of histamine- and allergen-induced skin reactions: comparison of first- and second-generation antihistamines. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20090601 |
| Analogs of MK-499 are differentially affected by a mutation in the S6 domain of the hERG K+ channel. | Biochemical pharmacology 20090515 |
| Relationship between airborne pollen count and treatment outcome in Japanese cedar pollinosis patients. | European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 20090501 |
| Managing toxicities and optimal dosing of targeted drugs in advanced kidney cancer. | Current oncology (Toronto, Ont.) 20090501 |
| A review of the efficacy of desloratadine, fexofenadine, and levocetirizine in the treatment of nasal congestion in patients with allergic rhinitis. | Clinical therapeutics 20090501 |
| Enantioselective disposition of fexofenadine with the P-glycoprotein inhibitor verapamil. | British journal of clinical pharmacology 20090501 |
| In vitro metabolism and inhibitory effects of pranlukast in human liver microsomes. | Biological & pharmaceutical bulletin 20090401 |
| Multiple H1-antihistamine-induced urticaria. | The Journal of dermatology 20090401 |
| Docking model of drug binding to the human ether-à-go-go potassium channel guided by tandem dimer mutant patch-clamp data: a synergic approach. | Journal of medicinal chemistry 20090326 |
| Safety of the novel atrial-selective K+-channel blocker AVE0118 in experimental heart failure. | Naunyn-Schmiedeberg's archives of pharmacology 20090301 |
| The inhibition of human multidrug and toxin extrusion 1 is involved in the drug-drug interaction caused by cimetidine. | Drug metabolism and disposition: the biological fate of chemicals 20090301 |
| Fexofenadine brain exposure and the influence of blood-brain barrier P-glycoprotein after fexofenadine and terfenadine administration. | Drug metabolism and disposition: the biological fate of chemicals 20090301 |
| Psychoactive medication and traffic safety. | International journal of environmental research and public health 20090301 |
| Calculation of QT shift in non clinical safety pharmacology studies. | Journal of pharmacological and toxicological methods 20090101 |
| Solar urticaria successfully treated with intravenous immunoglobulins. | Dermatology (Basel, Switzerland) 20090101 |
| Noninvasive technique for measurement of heartbeat regularity in zebrafish (Danio rerio) embryos. | BMC biotechnology 20090101 |
| IL-16 variability and modulation by antiallergic drugs in a murine experimental allergic rhinitis model. | International archives of allergy and immunology 20090101 |
| Influence of epinastine hydrochloride, an H1-receptor antagonist, on the function of mite allergen-pulsed murine bone marrow-derived dendritic cells in vitro and in vivo. | Mediators of inflammation 20090101 |
| Induction of mast cell accumulation, histamine release and skin edema by N49 phospholipase A2. | BMC immunology 20090101 |
| Validation of a voltage-sensitive dye (di-4-ANEPPS)-based method for assessing drug-induced delayed repolarisation in beagle dog left ventricular midmyocardial myocytes. | Journal of pharmacological and toxicological methods 20090101 |
| Role of atazanavir in the treatment of HIV infection. | Therapeutics and clinical risk management 20090101 |
| Fluticasone furoate nasal spray is more effective than fexofenadine for nighttime symptoms of seasonal allergy. | Allergy and asthma proceedings 20090101 |
| Evaluation of the efficacy and safety of olopatadine and fexofenadine compared with placebo in Japanese cedar pollinosis using an environmental exposure unit. | Journal of investigational allergology & clinical immunology 20090101 |
| Long-term effects of Panax ginseng on disposition of fexofenadine in rats in vivo. | The American journal of Chinese medicine 20090101 |
| Bioequivalence of fexofenadine tablet formulations assessed in healthy Iranian volunteers. | Arzneimittel-Forschung 20090101 |
| Engineering and validation of a novel lipid thin film for biomembrane modeling in lipophilicity determination of drugs and xenobiotics. | Journal of biological engineering 20090101 |
| Mechanistic modeling of hepatic transport from cells to whole body: application to napsagatran and fexofenadine. | Molecular pharmaceutics 20090101 |
| Drugs associated with more suicidal ideations are also associated with more suicide attempts. | PloS one 20090101 |
| Efficacy of repeated pretreatment with olopatadine hydrochloride on rhinitis induced by intranasal instillation of toluene-2,4-diisocyanate in rats. | Pharmacology 20090101 |
| Treatment of allergic rhinitis in infants and children: efficacy and safety of second-generation antihistamines and the leukotriene receptor antagonist montelukast. | Drugs 20090101 |
| Sudden elevation of liver enzymes in a 64-year-old patient: a case report. | Cases journal 20090101 |
| Treating rhinitis in the older population: special considerations. | Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology 20090101 |
| Chronic urticaria and treatment options. | Indian journal of dermatology 20090101 |
| Effects of fexofenadine on inflammatory mediators in nasal lavage fluid in intermittent allergic rhinitis. | Journal of investigational allergology & clinical immunology 20090101 |
| Contact urticaria: present scenario. | Indian journal of dermatology 20090101 |
| Management of difficult urticaria. | Indian journal of dermatology 20090101 |
| Psoriasis vulgaris and digestive system disorders: is there a linkage? | Folia histochemica et cytobiologica 20090101 |
| Update on terbinafine with a focus on dermatophytoses. | Clinical, cosmetic and investigational dermatology 20090101 |
| Ebastine in the light of CONGA recommendations for the development of third-generation antihistamines. | Journal of asthma and allergy 20090101 |
| QTc prolongation assessment in anticancer drug development: clinical and methodological issues. | Ecancermedicalscience 20090101 |
| Involvement of intestinal uptake transporters in the absorption of azithromycin and clarithromycin in the rat. | Drug metabolism and disposition: the biological fate of chemicals 20081201 |
| Design, data analysis, and simulation of in vitro drug transport kinetic experiments using a mechanistic in vitro model. | Drug metabolism and disposition: the biological fate of chemicals 20081201 |
| An ion channel library for drug discovery and safety screening on automated platforms. | Assay and drug development technologies 20081201 |
| Drug binding to the inactivated state is necessary but not sufficient for high-affinity binding to human ether-à-go-go-related gene channels. | Molecular pharmacology 20081101 |
| Narrowband ultraviolet B phototherapy is beneficial in antihistamine-resistant symptomatic dermographism: a pilot study. | Journal of the American Academy of Dermatology 20081101 |
| Potential benefit from an H1-receptor antagonist on postexercise syncope in the heat. | Medicine and science in sports and exercise 20081101 |
| Cyamemazine metabolites: effects on human cardiac ion channels in-vitro and on the QTc interval in guinea pigs. | The Journal of pharmacy and pharmacology 20081101 |
| Activation of proteinase-activated receptors induces itch-associated response through histamine-dependent and -independent pathways in mice. | Journal of pharmacological sciences 20081101 |
| Molecular determinants of hERG channel block by terfenadine and cisapride. | Journal of pharmacological sciences 20081101 |
| Validation of the use of nonnaive surgically catheterized rats for pharmacokinetics studies. | Journal of the American Association for Laboratory Animal Science : JAALAS 20081101 |
| Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. | Journal of medicinal chemistry 20081009 |
| Effectiveness of twice daily azelastine nasal spray in patients with seasonal allergic rhinitis. | Therapeutics and clinical risk management 20081001 |
| Mechanism of ritonavir changes in methadone pharmacokinetics and pharmacodynamics: II. Ritonavir effects on CYP3A and P-glycoprotein activities. | Clinical pharmacology and therapeutics 20081001 |
| Autonomic nervous system and cardiovascular system. | Indian journal of pharmacology 20081001 |
| Relative contribution of absorptive and secretory transporters to the intestinal absorption of fexofenadine in rats. | International journal of pharmaceutics 20080901 |
| Torsades de pointes liability inter-model comparisons: the experience of the QT PRODACT initiative. | Pharmacology & therapeutics 20080801 |
| Small mouse cholangiocytes proliferate in response to H1 histamine receptor stimulation by activation of the IP3/CaMK I/CREB pathway. | American journal of physiology. Cell physiology 20080801 |
| Probenecid, but not cystic fibrosis, alters the total and renal clearance of fexofenadine. | Journal of clinical pharmacology 20080801 |
| Literature-based evaluation of four 'hard endpoint' models for assessing drug-induced torsades de pointes liability. | British journal of pharmacology 20080801 |
| Fexofenadine effects on cognitive performance in aviators at ground level and simulated altitude. | Aviation, space, and environmental medicine 20080801 |
| Assessing QT prolongation in conscious dogs: validation of a beat-to-beat method. | Pharmacology & therapeutics 20080801 |
| The effects of topical (gel) astemizole and terfenadine on wound healing. | Indian journal of pharmacology 20080801 |
| A statistical methodology for drug-drug interaction surveillance. | Statistics in medicine 20080720 |
| A simple and rapid high performance liquid chromatographic method with fluorescence detection for the estimation of fexofenadine in rat plasma--application to preclinical pharmacokinetics. | Talanta 20080715 |
| Evaluation of the antihistamine effects of olopatadine, cetirizine and fexofenadine during a 24 h period: a double-blind, randomized, crossover, placebo-controlled comparison in skin responses induced by histamine iontophoresis. | Archives of dermatological research 20080701 |
| The effects of fexofenadine at steady-state on sleep architecture: a study using polysomnography in healthy Korean volunteers. | Expert opinion on pharmacotherapy 20080701 |
| Receptor-independent, vacuolar ATPase-mediated cellular uptake of histamine receptor-1 ligands: possible origin of pharmacological distortions and side effects. | Toxicology and applied pharmacology 20080615 |
| Spectrophotometric determination of terfenadine in pharmaceutical preparations by charge-transfer reactions. | Talanta 20080615 |
| Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). | Journal of medicinal chemistry 20080612 |
| Current industrial practices in assessing CYP450 enzyme induction: preclinical and clinical. | The AAPS journal 20080601 |
| Enzyme systems of detoxication - overview of recent approaches. | Interdisciplinary toxicology 20080601 |
| Identification of terfenadine as an inhibitor of human CD81-receptor HCV-E2 interaction: synthesis and structure optimization. | Molecules (Basel, Switzerland) 20080507 |
| Probing ligand binding modes of human cytochrome P450 2J2 by homology modeling, molecular dynamics simulation, and flexible molecular docking. | Proteins 20080501 |
| Involvement of multiple efflux transporters in hepatic disposition of fexofenadine. | Molecular pharmacology 20080501 |
| Practical recommendations on the use of lenalidomide in the management of myelodysplastic syndromes. | Annals of hematology 20080501 |
| Impact of basolateral multidrug resistance-associated protein (Mrp) 3 and Mrp4 on the hepatobiliary disposition of fexofenadine in perfused mouse livers. | Drug metabolism and disposition: the biological fate of chemicals 20080501 |
| The different effects of itraconazole on the pharmacokinetics of fexofenadine enantiomers. | British journal of clinical pharmacology 20080501 |
| Modest effect of impaired P-glycoprotein on the plasma concentrations of fexofenadine, quinidine, and loperamide following oral administration in collies. | Drug metabolism and disposition: the biological fate of chemicals 20080501 |
| Assessing QT prolongation in conscious dogs: validation of a beat-to-beat method. | Pharmacology & therapeutics 20080501 |
| Time-dependent inhibition of histamine-induced cutaneous responses by oral and intramuscular diphenhydramine and oral fexofenadine. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20080501 |
| Investigation of the inhibitory effects of various drugs on the hepatic uptake of fexofenadine in humans. | Drug metabolism and disposition: the biological fate of chemicals 20080401 |
| Analysis of disease-dependent sedative profiles of H(1)-antihistamines by large-scale surveillance using the visual analog scale. | Methods and findings in experimental and clinical pharmacology 20080401 |
| Prevention of chemotherapy-induced nausea and vomiting: focus on fosaprepitant. | Therapeutics and clinical risk management 20080401 |
| Terfenadine-induced apoptosis in human melanoma cells is mediated through Ca2+ homeostasis modulation and tyrosine kinase activity, independently of H1 histamine receptors. | Carcinogenesis 20080301 |
| Informatic tools and approaches in postmarketing pharmacovigilance used by FDA. | The AAPS journal 20080301 |
| Domoic acid toxicologic pathology: a review. | Marine drugs 20080301 |
| Deficient zebrafish ether-à-go-go-related gene channel gating causes short-QT syndrome in zebrafish reggae mutants. | Circulation 20080219 |
| Fexofenadine in pediatrics: oral tablet and suspension formulations. | Expert opinion on pharmacotherapy 20080201 |
| Effect of Ginkgo biloba extract on lopinavir, midazolam and fexofenadine pharmacokinetics in healthy subjects. | Current medical research and opinion 20080201 |
| A review of solifenacin in the treatment of urinary incontinence. | Therapeutics and clinical risk management 20080201 |
| Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model. | Journal of medicinal chemistry 20080124 |
| Isolation and structure elucidation of photodegradation products of fexofenadine. | Journal of pharmaceutical and biomedical analysis 20080122 |
| Development and validation of a rapid RP-HPLC method for the determination of cetirizine or fexofenadine with pseudoephedrine in binary pharmaceutical dosage forms. | Journal of pharmaceutical and biomedical analysis 20080122 |
| Aging-related changes of QT and RR intervals in conscious guinea pigs. | Journal of pharmacological and toxicological methods 20080101 |
| Multidrug resistance-associated protein 2 is primarily responsible for the biliary excretion of fexofenadine in mice. | Drug metabolism and disposition: the biological fate of chemicals 20080101 |
| Fexofenadine downmodulates antigen-presenting ability of murine epidermal Langerhans cells. | Journal of dermatological science 20080101 |
| Atopic cough-like cough hypersensitivity caused by active sensitization with protein fraction of Aspergillus restrictus strain A-17. | Pulmonary pharmacology & therapeutics 20080101 |
| Clinical pharmacokinetics and pharmacodynamics of desloratadine, fexofenadine and levocetirizine : a comparative review. | Clinical pharmacokinetics 20080101 |
| In vitro inhibition of rat basophilic leukaemia mast cell (RBL-2H3) degranulation by novel indane compounds. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20080101 |
| Non-interventional study comparing treatment satisfaction in patients treated with antihistamines. | Clinical drug investigation 20080101 |
| An overview of harms associated with beta-lactam antimicrobials: where do the carbapenems fit in? | Critical care (London, England) 20080101 |
| Pharmacokinetics, safety and tolerability of an oral suspension of fexofenadine for children with allergic rhinitis. | Allergy and asthma proceedings 20080101 |
| Comparative efficacy of levocetirizine, desloratidine and fexofenadine by histamine wheal suppression test. | Indian journal of dermatology, venereology and leprology 20080101 |
| Loratadine provides early symptom control in seasonal allergic rhinitis. | Allergy and asthma proceedings 20080101 |
| Role of cytochrome P450 in drug interactions. | Nutrition & metabolism 20080101 |
| Extended driving impairs nocturnal driving performances. | PloS one 20080101 |
| A novel approach to the prediction of drug-drug interactions in humans based on the serum incubation method. | Drug metabolism and pharmacokinetics 20080101 |
| Visualization of first-pass drug metabolism of terfenadine by MALDI-imaging mass spectrometry. | Drug metabolism letters 20080101 |
| Psychological factors in asthma. | Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology 20080101 |
| Alternative and improved method for the simultaneous determination of fexofenadine and pseudoephedrine in their combined tablet formulation. | Journal of pharmaceutical and biomedical analysis 20071221 |
| Antihistamine and sodium cromoglycate medication for food cold water exercise-induced anaphylaxis. | Allergy 20071201 |
| [Linear dermatitis due to shiitake mushrooms]. | Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20071201 |
| Two cases of alopecia areata responsive to fexofenadine. | The Journal of dermatology 20071201 |
| Safety and tolerability of fexofenadine hydrochloride, 15 and 30 mg, twice daily in children aged 6 months to 2 years with allergic rhinitis. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20071201 |
| Laser ablation electrospray ionization for atmospheric pressure, in vivo, and imaging mass spectrometry. | Analytical chemistry 20071101 |
| Fexofenadine/cyclodextrin inclusion complexation: phase solubility, thermodynamic, physicochemical, and computational analysis. | Drug development and industrial pharmacy 20071101 |
| Microdose clinical trial: quantitative determination of fexofenadine in human plasma using liquid chromatography/electrospray ionization tandem mass spectrometry. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20071015 |
| Suppressive activity of fexofenadine hydrochloride on nitric oxide production in-vitro and in-vivo. | The Journal of pharmacy and pharmacology 20071001 |
| Safety and tolerability of fexofenadine for the treatment of allergic rhinitis in children 2 to 5 years old. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20071001 |
| Measurements of blood pressure and electrocardiogram in conscious freely moving guineapigs: a model for screening QT interval prolongation effects. | Laboratory animals 20071001 |
| Detection and reporting of drug-induced proarrhythmias: room for improvement. | Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20070901 |
| Possible involvement of 5-lipoxygenase metabolite in itch-associated response of mosquito allergy in mice. | Journal of pharmacological sciences 20070901 |
| QT prolongation and safety in the Indian population. | Current drug safety 20070901 |
| Selective, competitive and mechanism-based inhibitors of human cytochrome P450 2J2. | Archives of biochemistry and biophysics 20070815 |
| Inhibition of the HERG potassium channel by the tricyclic antidepressant doxepin. | Biochemical pharmacology 20070801 |
| State dependent dissociation of HERG channel inhibitors. | British journal of pharmacology 20070801 |
| Current assessment of risk-benefit by regulators: is it time to introduce decision analyses? | Clinical pharmacology and therapeutics 20070801 |
| Formaldehyde-induced urticarial vasculitis. | The Australasian journal of dermatology 20070801 |
| Phase II testing of sunitinib: the National Cancer Institute of Canada Clinical Trials Group IND Program Trials IND.182-185. | Current oncology (Toronto, Ont.) 20070801 |
| Role of posaconazole in the management of oropharyngeal and esophageal candidiasis. | Therapeutics and clinical risk management 20070801 |
| Combination therapy using fexofenadine, disodium cromoglycate, and a hypoallergenic amino acid-based formula induced remission in a patient with steroid-dependent, chronically active ulcerative colitis. | International journal of colorectal disease 20070701 |
| Histamine and spontaneously released mast cell granules affect the cell growth of human hepatocellular carcinoma cells. | Experimental & molecular medicine 20070630 |
| Pharmacological characterization of a chronic pruritus model induced by multiple application of 2,4,6-trinitrochlorobenzene in NC mice. | European journal of pharmacology 20070601 |
| Toxicological significance of mechanism-based inactivation of cytochrome p450 enzymes by drugs. | Critical reviews in toxicology 20070601 |
| Bioequivalence of two fexofenadine formulations in healthy human volunteers after single oral administration. | Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia 20070601 |
| A brief review of moxifloxacin in the treatment of elderly patients with community-acquired pneumonia (CAP). | Clinical interventions in aging 20070601 |
| Montelukast in the management of allergic rhinitis. | Therapeutics and clinical risk management 20070601 |
| Hydroxypropyl beta-cyclodextrins: a misleading vehicle for the in vitro hERG current assay. | Journal of cardiovascular pharmacology 20070501 |
| Characterization of antihistamine-human serum protein interactions by capillary electrophoresis. | Journal of chromatography. A 20070420 |
| Naringin is a major and selective clinical inhibitor of organic anion-transporting polypeptide 1A2 (OATP1A2) in grapefruit juice. | Clinical pharmacology and therapeutics 20070401 |
| Effect of oral ketoconazole on intestinal first-pass effect of midazolam and fexofenadine in cynomolgus monkeys. | Drug metabolism and disposition: the biological fate of chemicals 20070301 |
| Intestinal drug transporter expression and the impact of grapefruit juice in humans. | Clinical pharmacology and therapeutics 20070301 |
| Pharmacokinetics of fexofenadine enantiomers in healthy subjects. | Chirality 20070301 |
| Influences of histamine H1 receptor antagonists on maximal electroshock seizure in infant rats. | Biological & pharmaceutical bulletin 20070301 |
| Enhancing effect of surfactants on fexofenadine.HCl transport across the human nasal epithelial cell monolayer. | International journal of pharmaceutics 20070207 |
| Evaluation of cryopreserved human hepatocytes as an alternative in vitro system to microsomes for the prediction of metabolic clearance. | Drug metabolism and disposition: the biological fate of chemicals 20070201 |
| Assessment of the first and second generation antihistamines brain penetration and role of P-glycoprotein. | Pharmaceutical research 20070201 |
| Quantification of fexofenadine in human plasma by liquid chromatography coupled to electrospray tandem mass spectrometry using mosapride as internal standard. | Biomedical chromatography : BMC 20070201 |
| Simple and reliable HPLC analysis of fexofenadine hydrochloride in tablets and its application to dissolution studies. | Die Pharmazie 20070201 |
| The effect of fexofenadine hydrochloride on productivity and quality of life in patients with chronic idiopathic urticaria. | Cutis 20070201 |
| Determination of fexofenadine enantiomers in human plasma with high-performance liquid chromatography. | Journal of pharmaceutical and biomedical analysis 20070117 |
| A novel approach to data processing of the QT interval response in the conscious telemetered beagle dog. | Journal of pharmacological and toxicological methods 20070101 |
| Teriparatide in postmenopausal women with osteoporosis and mild or moderate renal impairment. | Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20070101 |
| Differences in arrhythmogenicity between the canine right ventricular outflow tract and anteroinferior right ventricle in a model of Brugada syndrome. | Heart rhythm 20070101 |
| QT prolongation in guinea pigs for preliminary screening of torsadogenicity of drugs and drug-candidates. II. | Journal of applied toxicology : JAT 20070101 |
| Inhibition of cytokine-induced expression of T-cell cytokines by antihistamines. | Journal of investigational allergology & clinical immunology 20070101 |
| Synthesis and assessment of first-generation polyamidoamine dendrimer prodrugs to enhance the cellular permeability of P-gp substrates. | Bioconjugate chemistry 20070101 |
| Efficacy of fexofenadine versus desloratadine in suppressing histamine-induced wheal and flare. | Allergy and asthma proceedings 20070101 |
| Direct injection liquid chromatographic technique for simultaneous determination of two antihistaminic drugs and their main metabolites in serum. | Journal of AOAC International 20070101 |
| WJES and case reports/case series. | World journal of emergency surgery : WJES 20070101 |
| Evaluation of the guinea pig monophasic action potential (MAP) assay in predicting drug-induced delay of ventricular repolarisation using 12 clinically documented drugs. | Journal of pharmacological and toxicological methods 20070101 |
| Comparison of guinea-pig ventricular myocytes and dog Purkinje fibres for in vitro assessment of drug-induced delayed repolarization. | Journal of pharmacological and toxicological methods 20070101 |
| Comparison of the QT interval response during sinus and paced rhythm in conscious and anesthetized beagle dogs. | Journal of pharmacological and toxicological methods 20070101 |
| Some pharmacokinetic aspects of the lipophilic terfenadine and zwitterionic fexofenadine in humans. | Drugs in R&D 20070101 |
| Medicinal importance of grapefruit juice and its interaction with various drugs. | Nutrition journal 20070101 |
| Improved functional expression of recombinant human ether-a-go-go (hERG) K+ channels by cultivation at reduced temperature. | BMC biotechnology 20070101 |
| Food-dependent exercise-induced anaphylaxis: a case related to chickpea ingestion and review. | Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology 20070101 |
| Aprepitant: the evidence for its place in the prevention of chemotherapy-induced nausea and vomiting. | Core evidence 20070101 |
| The proarrhythmic antihistaminic drug terfenadine increases spontaneous calcium release in human atrial myocytes. | European journal of pharmacology 20061228 |
| Electrophysiological effects of brompheniramine on cardiac ion channels and action potential. | Pharmacological research 20061201 |
| Comparison of four rate-correction algorithms for the ventricular repolarization period in assessing net effects of IKr blockers in dogs. | Journal of pharmacological sciences 20061201 |
| Long QT syndrome in a patient with allergic rhinoconjunctivitis and auto-immune diabetes: focus on the choice of anti-H1 drugs. | European annals of allergy and clinical immunology 20061201 |
| The CML-related oncoprotein BCR/ABL induces expression of histidine decarboxylase (HDC) and the synthesis of histamine in leukemic cells. | Blood 20061115 |
| Lack of dose-dependent effects of itraconazole on the pharmacokinetic interaction with fexofenadine. | Drug metabolism and disposition: the biological fate of chemicals 20061101 |
| Inhibitory effect of carboxylic acid group on hERG binding. | Bioorganic & medicinal chemistry letters 20061101 |
| Treatment of allergic rhinitis can improve blood pressure control. | Journal of human hypertension 20061101 |
| Altering extracellular potassium concentration does not modulate drug block of human ether-a-go-go-related gene (hERG) channels. | Clinical and experimental pharmacology & physiology 20061101 |
| New antihistamines: a critical view. | Jornal de pediatria 20061101 |
| Ultrarush venom desensitization after systemic reactions during conventional venom immunotherapy. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20061101 |
| [Inhibition of histamine-induced wheel after a recommended single dose administration of 10 mg cetirizine, 5 mg desloratadine, 120 i 180 mg fexofenadine, 5 mg levocetirizine and 10 mg loratadine--a randomized, double-blind, placebo controlled trial]. | Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20061101 |
| [The effect of 5-days of cetirizine, desloratadine, fexofenadine 120 and 180 mg, levocetirizine, loratadine treatment on the histamine-induced skin reaction and skin blood flow--a randomized, double-blind, placebo controlled trial]. | Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20061101 |
| Involvement of ionotropic purinergic receptors in the histamine-induced enhancement of the cough reflex sensitivity in guinea pigs. | European journal of pharmacology 20061010 |
| QT interval prolongation and beyond. | Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc 20061001 |
| Onset of action of fexofenadine hydrochloride 60 mg/pseudoephedrine hydrochloride 120 mg in subjects aged 12 years with moderate to severe seasonal allergic rhinitis: a pooled analysis of two single-dose, randomized, double-blind, placebo-controlled allergen exposure unit studies. | Clinical therapeutics 20061001 |
| H1 histamine receptor antagonists induce genotoxic and caspase-2-dependent apoptosis in human melanoma cells. | Carcinogenesis 20060901 |
| Effects of single and multiple doses of itraconazole on the pharmacokinetics of fexofenadine, a substrate of P-glycoprotein. | British journal of clinical pharmacology 20060901 |
| Altered oral bioavailability and pharmacokinetics of P-glycoprotein substrates by coadministration of biochanin A. | Journal of pharmaceutical sciences 20060901 |
| Long QT 1 mutation KCNQ1A344V increases local anesthetic sensitivity of the slowly activating delayed rectifier potassium current. | Anesthesiology 20060901 |
| Hepatobiliary disposition of a drug/metabolite pair: Comprehensive pharmacokinetic modeling in sandwich-cultured rat hepatocytes. | The Journal of pharmacology and experimental therapeutics 20060801 |
| Facial thermography is a sensitive tool to determine antihistaminic activity: comparison of levocetirizine and fexofenadine. | British journal of clinical pharmacology 20060801 |
| Alteration of fexofenadine disposition in the rat isolated perfused liver following injection of bacterial lipopolysaccharide. | Clinical and experimental pharmacology & physiology 20060801 |
| Transporter-mediated intestinal absorption of fexofenadine in rats. | Drug metabolism and pharmacokinetics 20060801 |
| A combined neurophysiological and behavioural study into the stimulating effects of fexofenadine on performance. | Journal of psychopharmacology (Oxford, England) 20060701 |
| In vivo recording of adult zebrafish electrocardiogram and assessment of drug-induced QT prolongation. | American journal of physiology. Heart and circulatory physiology 20060701 |
| First-pass effects of verapamil on the intestinal absorption and liver disposition of fexofenadine in the porcine model. | Drug metabolism and disposition: the biological fate of chemicals 20060701 |
| Stimulating effects of the antihistamine fexofenadine: testing the dopamine transporter hypothesis. | Psychopharmacology 20060701 |
| Time-dependent interaction between lopinavir/ritonavir and fexofenadine. | Journal of clinical pharmacology 20060701 |
| Allergy medication in Japanese volunteers: treatment effect of single doses on nocturnal sleep architecture and next day residual effects. | Current medical research and opinion 20060701 |
| Application of a mathematical topological pattern of antihistaminic activity for the selection of new drug candidates and pharmacology assays. | Journal of medicinal chemistry 20060615 |
| Differences of promethazine and terfenadine on ion channels in guinea pig ventricular myocytes. | Chinese medical journal 20060605 |
| Efficacy and central nervous system impairment of newer-generation prescription antihistamines in seasonal allergic rhinitis. | Southern medical journal 20060601 |
| Voriconazole in the management of nosocomial invasive fungal infections. | Therapeutics and clinical risk management 20060601 |
| Cellular basis for trigger and maintenance of ventricular fibrillation in the Brugada syndrome model: high-resolution optical mapping study. | Journal of the American College of Cardiology 20060516 |
| Design and synthesis of selective, high-affinity inhibitors of human cytochrome P450 2J2. | Bioorganic & medicinal chemistry letters 20060515 |
| New insights about HERG blockade obtained from protein modeling, potential energy mapping, and docking studies. | Bioorganic & medicinal chemistry 20060501 |
| Inhibition of oat3-mediated renal uptake as a mechanism for drug-drug interaction between fexofenadine and probenecid. | Drug metabolism and disposition: the biological fate of chemicals 20060501 |
| Effect of P-glycoprotein on intestinal absorption and brain penetration of antiallergic agent bepotastine besilate. | Drug metabolism and disposition: the biological fate of chemicals 20060501 |
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 |
| Once-daily immediate-release fexofenadine and sustained-release pseudoephedrine combination: a new treatment option for allergic rhinitis. | Expert opinion on pharmacotherapy 20060501 |
| Effects of itraconazole and diltiazem on the pharmacokinetics of fexofenadine, a substrate of P-glycoprotein. | British journal of clinical pharmacology 20060501 |
| Pustular exacerbation of psoriasis due to fexofenadine. | Clinical and experimental dermatology 20060501 |
| Fexofenadine in horses: pharmacokinetics, pharmacodynamics and effect of ivermectin pretreatment. | Journal of veterinary pharmacology and therapeutics 20060401 |
| Effect of pretreatment with fexofenadine on the safety of immunotherapy in patients with allergic rhinitis. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20060401 |
| Dimethyl lithospermate B, an extract of Danshen, suppresses arrhythmogenesis associated with the Brugada syndrome. | Circulation 20060321 |
| Glutathione and thiolated chitosan inhibit multidrug resistance P-glycoprotein activity in excised small intestine. | Journal of controlled release : official journal of the Controlled Release Society 20060310 |
| Comparative evaluation of HERG currents and QT intervals following challenge with suspected torsadogenic and nontorsadogenic drugs. | The Journal of pharmacology and experimental therapeutics 20060301 |
| Long-term bradycardia caused by atrioventricular block can remodel the canine heart to detect the histamine H1 blocker terfenadine-induced torsades de pointes arrhythmias. | British journal of pharmacology 20060301 |
| The effect of short- and long-term administration of verapamil on the disposition of cytochrome P450 3A and P-glycoprotein substrates. | Clinical pharmacology and therapeutics 20060301 |
| [Extension of QT interval as a consequence of risk factor accumulation--case study]. | Vnitrni lekarstvi 20060301 |
| Effects of cyamemazine on hERG, INa, ICa, Ito, Isus and IK1 channel currents, and on the QTc interval in guinea pigs. | European journal of pharmacology 20060227 |
| Analysis of pharmaceutical preparations containing antihistamine drugs by micellar liquid chromatography. | Journal of pharmaceutical and biomedical analysis 20060213 |
| Efficacy of fexofenadine in the prophylactic control of cat allergen-induced allergic rhinitis. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20060201 |
| Effect of erythromycin on the absorption of fexofenadine in the jejunum, ileum and colon determined using local intubation in healthy volunteers. | International journal of clinical pharmacology and therapeutics 20060201 |
| Fexofenadine, an H1-receptor antagonist, partially but rapidly inhibits the itch of contact dermatitis induced by diphenylcyclopropenone in patients with alopecia areata. | The Journal of dermatology 20060201 |
| Potent pruritogenic action of tryptase mediated by PAR-2 receptor and its involvement in anti-pruritic effect of nafamostat mesilate in mice. | European journal of pharmacology 20060113 |
| Differential effects of fexofenadine on arachidonic acid metabolism in cultured human monocytes. | Pharmacology 20060101 |
| Long QT syndrome: reduced repolarization reserve and the genetic link. | Journal of internal medicine 20060101 |
| A novel predictive pharmacokinetic/pharmacodynamic model of repolarization prolongation derived from the effects of terfenadine, cisapride and E-4031 in the conscious chronic av node--ablated, His bundle-paced dog. | Journal of pharmacological and toxicological methods 20060101 |
| [Long QT interval. Interaction of terfenadine and itraconazole]. | Medizinische Monatsschrift fur Pharmazeuten 20060101 |
| Drug-induced QT prolongation: an update. | Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc 20060101 |
| Enzymatic characteristics of CYP3A5 and CYP3A4: a comparison of in vitro kinetic and drug-drug interaction patterns. | Xenobiotica; the fate of foreign compounds in biological systems 20060101 |
| Dimethyl sulfoxide effects on hERG channels expressed in HEK293 cells. | Journal of pharmacological and toxicological methods 20060101 |
| In vivo pharmacological characterisation of bilastine, a potent and selective histamine H1 receptor antagonist. | Drugs in R&D 20060101 |
| Dyspnea assessment and adverse events during sputum induction in COPD. | BMC pulmonary medicine 20060101 |
| Stimulating effects of H1-antagonists. | Current pharmaceutical design 20060101 |
| Efficacy of desloratadine, 5 mg, compared with fexofenadine, 180 mg, in patients with symptomatic seasonal allergic rhinitis. | Allergy and asthma proceedings 20060101 |
| Saliva secretion in patients with allergic rhinitis. | International archives of allergy and immunology 20060101 |
| Marketing of a new non-sedating antihistamine (fexofenadine) puts an additional burden on healthcare system resources in Israel. | The European journal of general practice 20060101 |
| Simultaneous quantification of fexofenadine and pseudoephedrine in human plasma by liquid chromatography/tandem mass spectrometry with electrospray ionization: method development, validation and application to a clinical study. | Rapid communications in mass spectrometry : RCM 20060101 |
| New evidence of H1-receptor independent COX-2 inhibition by fexofenadine HCl in vitro. | Pharmacology 20060101 |
| The effect of fexofenadine on pruritus in a mouse model (HR-ADf) of atopic dermatitis. | The Journal of international medical research 20060101 |
| Selecting the optimal oral antihistamine for patients with allergic rhinitis. | Drugs 20060101 |
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| [Treatment of allergic rhinitis associated with hypothyroidism]. | Vestnik otorinolaringologii 20060101 |
| The methanol disolvate and the dihydrate of fexofenadine, an antihistamine drug. | Acta crystallographica. Section C, Crystal structure communications 20051201 |
| Localized periorbital edema induced by Ibuprofen. | The Journal of dermatology 20051201 |
| The efficacy and safety of 30 mg fexofenadine HCl bid in pediatric patients with allergic rhinitis. | Asian Pacific journal of allergy and immunology 20051201 |
| Safety and tolerability of oral antifungal agents in the treatment of fungal nail disease: a proven reality. | Therapeutics and clinical risk management 20051201 |
| Drug-induced proarrhythmia and use of QTc-prolonging agents: clues for clinicians. | Heart rhythm 20051101 |
| hERG1 channels are overexpressed in glioblastoma multiforme and modulate VEGF secretion in glioblastoma cell lines. | British journal of cancer 20051003 |
| Contribution of OATP (organic anion-transporting polypeptide) family transporters to the hepatic uptake of fexofenadine in humans. | Drug metabolism and disposition: the biological fate of chemicals 20051001 |
| Effects of fexofenadine hydrochloride in a guinea pig model of antigen-induced rhinitis. | Pharmacology 20051001 |
| Reduction of repolarization reserve by halothane anaesthesia sensitizes the guinea-pig heart for drug-induced QT interval prolongation. | British journal of pharmacology 20051001 |
| Effects of fexofenadine and hydroxyzine on brake reaction time during car-driving with cellular phone use. | Human psychopharmacology 20051001 |
| Transport of anti-allergic drugs across the passage cultured human nasal epithelial cell monolayer. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20051001 |
| Brugada syndrome and ischemia-induced ST-segment elevation. Similarities and differences. | Journal of electrocardiology 20051001 |
| Treatment of ear pain in pilots in flight. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20051001 |
| The various effects of four H1-antagonists on serum substance P levels in patients with atopic dermatitis. | The Journal of dermatology 20051001 |
| Grape fruit juice-drug interactions. | Pakistan journal of pharmaceutical sciences 20051001 |
| [Wheat anaphylaxis enhanced by administration of acetylsalicylic acid or by exercise]. | Arerugi = [Allergy] 20051001 |
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| L-selectin expression on neutrophils from allergic patients. | Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20050901 |
| Suppression of the histamine-induced wheal and flare response by fexofenadine HCl 60 mg twice daily, loratadine 10 mg once daily and placebo in healthy Japanese volunteers. | Current medical research and opinion 20050901 |
| Addition of fexofenadine to inhaled corticosteroid therapy to reduce inflammatory biomarkers in atopic asthma. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20050901 |
| Determination of fexofenadine in tablets by capillary electrophoresis in free solution and in solution with cyclodextrins as analyte carriers. | Drug development and industrial pharmacy 20050901 |
| Histamine H1 receptor occupancy and pharmacodynamics of second generation H1-antihistamines. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20050901 |
| Suppression of matrix metalloproteinase production in nasal fibroblasts by tranilast, an antiallergic agent, in vitro. | Mediators of inflammation 20050814 |
| Development and validation of dissolution tests for fexofenadine hydrochloride capsules and coated tablets. | Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20050811 |
| Management of seasonal allergic rhinitis: comparative efficacy of the newer-generation prescription antihistamines. | Journal of the American Academy of Nurse Practitioners 20050801 |
| Effect of itraconazole on the pharmacokinetics and pharmacodynamics of fexofenadine in relation to the MDR1 genetic polymorphism. | Clinical pharmacology and therapeutics 20050801 |
| The advantages of the Ussing chamber in drug absorption studies. | Journal of biomolecular screening 20050801 |
| Assessing the therapeutic benefits of antihistamines for the treatment of chronic idiopathic urticaria--a requirement for well-designed comparative clinical studies. | The Journal of dermatological treatment 20050801 |
| Practical application of guinea pig telemetry system for QT evaluation. | The Journal of toxicological sciences 20050801 |
| P-glycoprotein plays a major role in the efflux of fexofenadine in the small intestine and blood-brain barrier, but only a limited role in its biliary excretion. | Drug metabolism and disposition: the biological fate of chemicals 20050701 |
| Levocetirizine has a longer duration of action on improving total nasal symptoms score than fexofenadine after single administration. | British journal of clinical pharmacology 20050701 |
| Take allergy drug and sniff flowers safely? | Consumer reports 20050601 |
| Once-daily fexofenadine treatment for chronic idiopathic urticaria: a multicenter, randomized, double-blind, placebo-controlled study. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20050601 |
| Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk). | Journal of medicinal chemistry 20050505 |
| Osteoporosis, teriparatide, and dosing of calcium and vitamin D. | The New England journal of medicine 20050505 |
| Fexofenadine pharmacokinetics are associated with a polymorphism of the SLCO1B1 gene (encoding OATP1B1). | British journal of clinical pharmacology 20050501 |
| QT interval prolongation and torsades de pointes due to a coadministration of metronidazole and amiodarone. | Pacing and clinical electrophysiology : PACE 20050501 |
| Single-dose and steady-state bioequivalence of fexofenadine and pseudoephedrine combination tablets compared with individual formulations in healthy adults. | Current medical research and opinion 20050501 |
| A pharmacophore hypothesis for P-glycoprotein substrate recognition using GRIND-based 3D-QSAR. | Journal of medicinal chemistry 20050421 |
| Preferential downmodulation of certain chemokines by fexofenadine in human keratinocytes. | Journal of dermatological science 20050401 |
| The efficacy of short-term administration of 3 antihistamines vs placebo under natural exposure to Japanese cedar pollen. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20050401 |
| Effect of trazodone on hERG channel current and QT-interval. | European journal of pharmacology 20050307 |
| H1 receptor-mediated vasodilatation contributes to postexercise hypotension. | The Journal of physiology 20050301 |
| CYP3A and P-glycoprotein activity induction with St. John's Wort in healthy volunteers from 6 ethnic populations. | Journal of clinical pharmacology 20050301 |
| Effect of grapefruit juice volume on the reduction of fexofenadine bioavailability: possible role of organic anion transporting polypeptides. | Clinical pharmacology and therapeutics 20050301 |
| Inhibition of tryptase release from human colon mast cells by histamine receptor antagonists. | Asian Pacific journal of allergy and immunology 20050301 |
| Clinical outcomes and management of mechanism-based inhibition of cytochrome P450 3A4. | Therapeutics and clinical risk management 20050301 |
| Effect of fruit juices on the oral bioavailability of fexofenadine in rats. | Journal of pharmaceutical sciences 20050201 |
| Fexofenadine improves the quality of life and work productivity in Japanese patients with seasonal allergic rhinitis during the peak cedar pollinosis season. | International archives of allergy and immunology 20050201 |
| Identification of human P450 isoforms involved in the metabolism of the antiallergic drug, oxatomide, and its kinetic parameters and inhibition constants. | Biological & pharmaceutical bulletin 20050201 |
| [Torsades de pointes caused by cetirizine overdose]. | Archives des maladies du coeur et des vaisseaux 20050201 |
| Evaluation of first-pass cytochrome P4503A (CYP3A) and P-glycoprotein activities using alfentanil and fexofenadine in combination. | Journal of clinical pharmacology 20050101 |
| Different effects of three transporting inhibitors, verapamil, cimetidine, and probenecid, on fexofenadine pharmacokinetics. | Clinical pharmacology and therapeutics 20050101 |
| Mechanism-based inhibition of cytochrome P450 3A4 by therapeutic drugs. | Clinical pharmacokinetics 20050101 |
| Minimal important difference (MID) of the Dermatology Life Quality Index (DLQI): results from patients with chronic idiopathic urticaria. | Health and quality of life outcomes 20050101 |
| Use of a five-channel multiplexed electrospray quadrupole time-of-flight hybrid mass spectrometer for metabolite identification. | Rapid communications in mass spectrometry : RCM 20050101 |
| Estimation of potency of HERG channel blockers: impact of voltage protocol and temperature. | Journal of pharmacological and toxicological methods 20050101 |
| Cardiovascular parameters in anaesthetized guinea pigs: a safety pharmacology screening model. | Journal of pharmacological and toxicological methods 20050101 |
| Structural determinants for high-affinity block of hERG potassium channels. | Novartis Foundation symposium 20050101 |
| In vivo antimuscarinic actions of the third generation antihistaminergic agent, desloratadine. | BMC pharmacology 20050101 |
| Comparative effects of fexofenadine and montelukast on allergen-induced wheal and flare. | Allergy and asthma proceedings 20050101 |
| Capillary electrophoresis method for fexofenadine hydrochloride in capsules. | Journal of AOAC International 20050101 |
| Comparative efficacy of cetirizine and fexofenadine for seasonal allergic rhinitis, 5-12 hours postdose, in the environmental exposure unit. | Allergy and asthma proceedings 20050101 |
| The effect of fexofenadine on expression of intercellular adhesion molecule 1 and induction of apoptosis on peripheral eosinophils. | Allergy and asthma proceedings 20050101 |
| A Chronic Fatigue Syndrome - related proteome in human cerebrospinal fluid. | BMC neurology 20050101 |
| Greater risk of incident asthma cases in adults with allergic rhinitis and effect of allergen immunotherapy: a retrospective cohort study. | Respiratory research 20050101 |
| QT PRODACT: a multi-site study of in vitro action potential assays on 21 compounds in isolated guinea-pig papillary muscles. | Journal of pharmacological sciences 20050101 |
| QT PRODACT: in vivo QT assay in the conscious dog for assessing the potential for QT interval prolongation by human pharmaceuticals. | Journal of pharmacological sciences 20050101 |
| QT PRODACT: in vivo QT assay with a conscious monkey for assessment of the potential for drug-induced QT interval prolongation. | Journal of pharmacological sciences 20050101 |
| QT PRODACT: sensitivity and specificity of the canine telemetry assay for detecting drug-induced QT interval prolongation. | Journal of pharmacological sciences 20050101 |
| Simultaneous determination of ebastine and its three metabolites in plasma using liquid chromatography-tandem mass spectrometry. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20041225 |
| Evidence of significant contribution from CYP3A5 to hepatic drug metabolism. | Drug metabolism and disposition: the biological fate of chemicals 20041201 |
| The utility of mixed-effects covariate analysis in rapid selection of doses in pediatric subjects: a case study with fexofenadine hydrochloride. | Biopharmaceutics & drug disposition 20041201 |
| Similar rapid onset of action and magnitude of effect of fexofenadine and cetirizine as assessed by inhibition of histamine-induced wheal-and-flare reaction. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20041201 |
| Suppressive activity of fexofenadine hydrochloride on metalloproteinase production from nasal fibroblasts in vitro. | Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20041201 |
| Microbial oxidation of terfenadine and ebastine into fexofenadine and carebastine. | Bioorganic & medicinal chemistry letters 20041101 |
| A variant 2677A allele of the MDR1 gene affects fexofenadine disposition. | Clinical pharmacology and therapeutics 20041101 |
| Comparative pharmacology of guinea pig cardiac myocyte and cloned hERG (I(Kr)) channel. | Journal of cardiovascular electrophysiology 20041101 |
| The crystallisation of a model hydrophobic drug (terfenadine) following exposure to humidity and organic vapours. | International journal of pharmaceutics 20041013 |
| Comparison of alamar blue and MTT assays for high through-put screening. | Toxicology in vitro : an international journal published in association with BIBRA 20041001 |
| Steady-state brain concentrations of antihistamines in rats: interplay of membrane permeability, P-glycoprotein efflux and plasma protein binding. | Pharmacology 20041001 |
| Automated tight seal electrophysiology for assessing the potential hERG liability of pharmaceutical compounds. | Assay and drug development technologies 20041001 |
| Effects of bepotastine, cetirizine, fexofenadine, and olopatadine on histamine-induced wheal-and flare-response, sedation, and psychomotor performance. | Clinical and experimental dermatology 20040901 |
| Drug-drug interactions of Z-338, a novel gastroprokinetic agent, with terfenadine, comparison with cisapride, and involvement of UGT1A9 and 1A8 in the human metabolism of Z-338. | European journal of pharmacology 20040823 |
| Terfenadine induces thymocyte apoptosis via mitochondrial pathway. | European journal of pharmacology 20040802 |
| Venom immunotherapy: adverse reactions and treatment failure. | Current opinion in allergy and clinical immunology 20040801 |
| Central effects of fexofenadine and cetirizine: measurement of psychomotor performance, subjective sleepiness, and brain histamine H1-receptor occupancy using 11C-doxepin positron emission tomography. | Journal of clinical pharmacology 20040801 |
| Comparison of pharmacokinetics and metabolism of desloratadine, fexofenadine, levocetirizine and mizolastine in humans. | Fundamental & clinical pharmacology 20040801 |
| Validation of the Dermatology Life Quality Index as an outcome measure for urticaria-related quality of life. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20040801 |
| Efficacy of azelastine nasal spray in seasonal allergic rhinitis patients who remain symptomatic after treatment with fexofenadine. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20040801 |
| A novel membrane sensor for histamine H1-receptor antagonist 'fexofenadine'. | Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20040801 |
| Transport characteristics of fexofenadine in the Caco-2 cell model. | Pharmaceutical research 20040801 |
| Intradermal nociceptin elicits itch-associated responses through leukotriene B(4) in mice. | The Journal of investigative dermatology 20040701 |
| Validation of a [3H]astemizole binding assay in HEK293 cells expressing HERG K+ channels. | Journal of pharmacological sciences 20040701 |
| Role of sodium and calcium channel block in unmasking the Brugada syndrome. | Heart rhythm 20040701 |
| Determination of fexofenadine in human plasma using 96-well solid phase extraction and HPLC with tandem mass spectrometric detection. | Journal of pharmaceutical and biomedical analysis 20040629 |
| Liquid chromatographic determination of fexofenadine in human plasma with fluorescence detection. | Journal of pharmaceutical and biomedical analysis 20040629 |
| Drugs, hERG and sudden death. | Cell calcium 20040601 |
| Effects of single or combined histamine H1-receptor and leukotriene CysLT1-receptor antagonism on nasal adenosine monophosphate challenge in persistent allergic rhinitis. | British journal of clinical pharmacology 20040601 |
| Lead identification for modulators of multidrug resistance based on in silico screening with a pharmacophoric feature model. | Archiv der Pharmazie 20040601 |
| Safety and efficacy of oral fexofenadine in children with seasonal allergic rhinitis--a pooled analysis of three studies. | Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 20040601 |
| Involvement of histamine H4 and H1 receptors in scratching induced by histamine receptor agonists in Balb C mice. | British journal of pharmacology 20040501 |
| Molecular determinants for high-affinity block of human EAG potassium channels by antiarrhythmic agents. | Molecular pharmacology 20040501 |
| Fexofenadine does not affect omeprazole pharmacokinetics: both are putative P-glycoprotein substrates. | Basic & clinical pharmacology & toxicology 20040501 |
| Inactivation gating determines drug potency: a common mechanism for drug blockade of HERG channels. | Acta pharmacologica Sinica 20040501 |
| Acid-base cosolvent method for determining aqueous permeability of amiodarone, itraconazole, tamoxifen, terfenadine and other very insoluble molecules. | Chemical & pharmaceutical bulletin 20040501 |
| Identification of human p450 isoforms involved in the metabolism of the antiallergic drug, oxatomide, and its inhibitory effect on enzyme activity. | Biological & pharmaceutical bulletin 20040501 |
| Comparative efficacy of wheal-and-flare suppression among various non-sedating antihistamines and the pharmacologic insights to their efficacy. | Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20040501 |
| Integrating in vitro kinetic data from compounds exhibiting induction, reversible inhibition and mechanism-based inactivation: in vitro study design. | Current drug metabolism 20040401 |
| Repeated dosing effects of mediator antagonists in inhaled corticosteroid-treated atopic asthmatic patients. | Chest 20040401 |
| A placebo-controlled evaluation of butterbur and fexofenadine on objective and subjective outcomes in perennial allergic rhinitis. | Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20040401 |
| Comparative effects of desloratadine, fexofenadine, and levocetirizine on nasal adenosine monophosphate challenge in patients with perennial allergic rhinitis. | Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20040401 |
| Lack of association between fexofenadine and rhabdomyolysis. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20040401 |
| Mizolastine and fexofenadine modulate cytokine pattern after nasal allergen challenge. | European annals of allergy and clinical immunology 20040401 |
| Physicochemical features of the HERG channel drug binding site. | The Journal of biological chemistry 20040312 |
| Suppressive activity of fexofenadine hydrochloride on thymus- and activation-regulated chemokine production from human peripheral blood leukocytes in response to antigenic stimulation in vitro. | International archives of allergy and immunology 20040301 |
| The effects of fexofenadine on eosinophilia and systemic anaphylaxis in mice infected with Trichinella spiralis. | International immunopharmacology 20040301 |
| Antihistamines and driving ability: evidence from on-the-road driving studies during normal traffic. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20040301 |
| Polymorphism in generic drug product development. | Advanced drug delivery reviews 20040223 |
| Differential effect of HERG blocking agents on cardiac electrical alternans in the guinea pig. | European journal of pharmacology 20040220 |
| Application of data mining techniques in pharmacovigilance. | British journal of clinical pharmacology 20040201 |
| The effects of butterbur on the histamine and allergen cutaneous response. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20040201 |
| Assessing patient satisfaction with desloratadine after conversion from loratadine, fexofenadine, or cetirizine. | Managed care interface 20040201 |
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| Anti-inflammatory activity of H1-receptor antagonists: review of recent experimental research. | Current medical research and opinion 20040101 |
| Comparative efficacy of cetirizine and fexofenadine in the treatment of chronic idiopathic urticaria. | The Journal of dermatological treatment 20040101 |
| Comparison of the combinations of fexofenadine-pseudoephedrine and loratadine-montelukast in the treatment of seasonal allergic rhinitis. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20040101 |
| Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20040101 |
| Randomized double-blind comparison of cetirizine and fexofenadine after pollen challenge in the Environmental Exposure Unit: duration of effect in subjects with seasonal allergic rhinitis. | Allergy and asthma proceedings 20040101 |
| Association between the number of coadministered P-glycoprotein inhibitors and serum digoxin levels in patients on therapeutic drug monitoring. | BMC medicine 20040101 |
| Quinolone safety and efficacy more important than potency. | Emerging infectious diseases 20040101 |
| Prolonged effect of an H1-receptor blocker antihistamine on the histamine content of white blood cells and mast cells. | Cell biochemistry and function 20040101 |
| Onset of action for the relief of allergic rhinitis symptoms with second-generation antihistamines. | Allergy and asthma proceedings 20040101 |
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| Suppressive activity of fexofenadine hydrochloride on the production of eosinophil chemoattractants from human nasal fibroblasts in vitro. | Arzneimittel-Forschung 20040101 |
| Development and validation of a liquid chromatographic method for fexofenadine hydrochloride in capsules. | Journal of AOAC International 20040101 |
| Improved precision and accuracy for high-performance liquid chromatography/Fourier transform ion cyclotron resonance mass spectrometric exact mass measurement of small molecules from the simultaneous and controlled introduction of internal calibrants via a second electrospray nebuliser. | Rapid communications in mass spectrometry : RCM 20040101 |
| Clinical study of the therapeutic efficacy and safety of emedastine difumarate versus terfenadine in the treatment of seasonal allergic rhinitis. | Arzneimittel-Forschung 20040101 |
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| Zebrafish embryos express an orthologue of HERG and are sensitive toward a range of QT-prolonging drugs inducing severe arrhythmia. | Toxicology and applied pharmacology 20031215 |
| Atrioventricular nodal ablation and His-bundle pacing: an acute canine model for proarrhythmic risk assesment. | Journal of cardiovascular electrophysiology 20031201 |
| Comparative study of acute effects of single doses of fexofenadine, olopatadine, d-chlorpheniramine and placebo on psychomotor function in healthy volunteers. | Human psychopharmacology 20031201 |
| Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20031201 |
| Effects of imatinib mesylate (STI571, Glivec) on the pharmacokinetics of simvastatin, a cytochrome p450 3A4 substrate, in patients with chronic myeloid leukaemia. | British journal of cancer 20031117 |
| Multiple transport mechanisms involved in the intestinal absorption and first-pass extraction of fexofenadine. | Clinical pharmacology and therapeutics 20031101 |
| A study comparing the inhibitory effects of single and repeated oral doses of ebastine and fexofenadine against histamine-induced skin reactivity. | International archives of allergy and immunology 20031101 |
| Effect of the second-generation antihistamine, fexofenadine, on cough reflex sensitivity and pulmonary function. | British journal of clinical pharmacology 20031101 |
| Mite-antigen induced immediate reactions in atopic dermatitis are inhibited by daily administration of fexofenadine. | The Journal of dermatology 20031101 |
| [Drug interactions. Mechanisms and clinical relevance]. | Der Internist 20031101 |
| Efficacy and safety profile of fexofenadine HCl: a unique therapeutic option in H1-receptor antagonist treatment. | The Journal of allergy and clinical immunology 20031001 |
| Effects of fexofenadine and other antihistamines on components of the allergic response: adhesion molecules. | The Journal of allergy and clinical immunology 20031001 |
| Effects of fexofenadine on T-cell function in a murine model of allergen-induced airway inflammation and hyperresponsiveness. | The Journal of allergy and clinical immunology 20031001 |
| Prospects for antihistamines in the treatment of asthma. | The Journal of allergy and clinical immunology 20031001 |
| Is 3-mm less drowsiness important? | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20031001 |
| Fexofenadine hydrochloride, 180 mg, exhibits equivalent efficacy to cetirizine, 10 mg, with less drowsiness in patients with moderate-to-severe seasonal allergic rhinitis. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20031001 |
| H1-receptor blocker antihistamine, terfenadine durably influences the glucocorticoid receptor, and lymphocyte histamine content of weanling rats. | Pharmacological research 20030901 |
| Terfenadine antagonism against interleukin-4-modulated gene expression of T cell cytokines. | The Journal of investigative dermatology 20030901 |
| Demethylation of radiolabelled dextromethorphan in rat microsomes and intact hepatocytes. | European journal of biochemistry 20030901 |
| [Observation on effect of integrative Chinese and Western medicine in treating acute attack of bronchial asthma]. | Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20030901 |
| Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods. | Bioorganic & medicinal chemistry letters 20030818 |
| Sudden arrhythmia death syndrome: importance of the long QT syndrome. | American family physician 20030801 |
| Rapid assessment of P-glycoprotein inhibition and induction in vitro. | Pharmaceutical research 20030801 |
| Omalizumab, an anti-IgE antibody, in the treatment of adults and adolescents with perennial allergic rhinitis. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20030801 |
| The effects of fexofenadine on reaction time, decision-making, and driver behavior. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20030801 |
| Randomized, double-masked comparison of olopatadine ophthalmic solution, mometasone furoate monohydrate nasal spray, and fexofenadine hydrochloride tablets using the conjunctival and nasal allergen challenge models. | Clinical therapeutics 20030801 |
| RNA synthesis-dependent potentiation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor-mediated toxicity by antihistamine terfenadine in cultured rat cerebellar neurons. | Neuroscience letters 20030717 |
| Inhibition of experimental allergic rhinitis by the n-butanol fraction from the anomalous fruits of Gleditsia sinensis. | Biological & pharmaceutical bulletin 20030701 |
| Herbal supplements and skin testing: the lack of effect of commonly used herbal supplements on histamine skin prick testing. | Allergy 20030601 |
| Supplementation of fexofenadine therapy with nedocromil sodium 2% ophthalmic solution to treat ocular symptoms of seasonal allergic conjunctivitis. | Clinical & experimental ophthalmology 20030601 |
| H1-antihistaminic activity of cetirizine and fexofenadine in allergic children. | Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 20030601 |
| Pregnancy outcome after gestational exposure to loratadine or antihistamines: a prospective controlled cohort study. | The Journal of allergy and clinical immunology 20030601 |
| Addition of fexofenadine to a topical corticosteroid reduces the pruritus associated with atopic dermatitis in a 1-week randomized, multicentre, double-blind, placebo-controlled, parallel-group study. | The British journal of dermatology 20030601 |
| [Effects of clinically available drugs on the repolarization process of the heart assessed by the in vivo canine models]. | Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20030601 |
| Relative potency of fexofenadine HCl 180 mg, loratadine 10 mg, and placebo using a skin test model of wheal-and-flare suppression. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20030601 |
| In vitro inhibition of human small intestinal and liver microsomal astemizole O-demethylation: different contribution of CYP2J2 in the small intestine and liver. | Xenobiotica; the fate of foreign compounds in biological systems 20030601 |
| [Clinical aspects of anti-inflammatory action of antihistamines]. | Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20030601 |
| Histamine H1 receptor antagonism by cetirizine in isolated guinea pig tissues: influence of receptor reserve and dissociation kinetics. | European journal of pharmacology 20030530 |
| Understanding the structure-activity relationship of the human ether-a-go-go-related gene cardiac K+ channel. A model for bad behavior. | Journal of medicinal chemistry 20030522 |
| Characterization of HERG potassium channel inhibition using CoMSiA 3D QSAR and homology modeling approaches. | Bioorganic & medicinal chemistry letters 20030519 |
| Voltage-dependent profile of human ether-a-go-go-related gene channel block is influenced by a single residue in the S6 transmembrane domain. | Molecular pharmacology 20030501 |
| Molecular mechanisms of G0/G1 cell-cycle arrest and apoptosis induced by terfenadine in human cancer cells. | Molecular carcinogenesis 20030501 |
| Effects of fexofenadine, diphenhydramine, and placebo on performance of the test of variables of attention (TOVA). | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20030501 |
| Characteristics of the antihistamine effect of TAK-427, a novel imidazopyridazine derivative. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20030501 |
| A single-center, randomized, double-blind, placebo-controlled, crossover investigation of the effects of fexofenadine hydrochloride 180 mg alone and with alcohol, with hydroxyzine hydrochloride 50 mg as a positive internal control, on aspects of cognitive and psychomotor function related to driving a car. | Clinical therapeutics 20030501 |
| Comparison of in vitro P-glycoprotein screening assays: recommendations for their use in drug discovery. | Journal of medicinal chemistry 20030424 |
| Famotidine does not induce long QT syndrome: experimental evidence from in vitro and in vivo test systems. | European journal of pharmacology 20030411 |
| Fexofenadine is efficacious and safe in children (aged 6-11 years) with seasonal allergic rhinitis. | The Journal of allergy and clinical immunology 20030401 |
| Sedation and performance impairment of diphenhydramine and second-generation antihistamines: a meta-analysis. | The Journal of allergy and clinical immunology 20030401 |
| The effects of acute doses of fexofenadine, promethazine, and placebo on cognitive and psychomotor function in healthy Japanese volunteers. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20030401 |
| Photomutagenic properties of terfenadine as revealed by a stepwise photostability, phototoxicity and photomutagenicity testing approach. | Photochemistry and photobiology 20030401 |
| [H1 histamine antagonists]. | Revue medicale de Bruxelles 20030401 |
| Drugs that induce repolarization abnormalities cause bradycardia in zebrafish. | Circulation 20030318 |
| Decongestant effects of antihistamines: a class effect? | The Journal of allergy and clinical immunology 20030301 |
| Solar urticaria induced by infrared radiation. | Clinical and experimental dermatology 20030301 |
| Inhibitory effect of azelastine on allergic itch-associated response in mice sensitized with mosquito salivary glands extract. | Journal of pharmacological sciences 20030301 |
| Detection of proarrhythmia in the female rabbit heart: blinded validation. | Journal of cardiovascular electrophysiology 20030301 |
| Effect of fexofenadine hydrochloride on cedar pollinosis. | Auris, nasus, larynx 20030201 |
| Failure of cetirizine and fexofenadine to prevent motion sickness. | The Annals of pharmacotherapy 20030201 |
| Synthesis of eosinophil infiltration inhibitors with antihistaminic activity. | Chemical & pharmaceutical bulletin 20030201 |
| The effect of ketoconazole on the in vivo intestinal permeability of fexofenadine using a regional perfusion technique. | British journal of clinical pharmacology 20030201 |
| Comparative in vivo bioactivity of modern H1-antihistamines on AMP challenge in atopic asthma. | The Journal of allergy and clinical immunology 20030201 |
| The effects of single-dose fexofenadine, diphenhydramine, and placebo on cognitive performance in flight personnel. | Aviation, space, and environmental medicine 20030201 |
| Functional and pharmacological properties of canine ERG potassium channels. | American journal of physiology. Heart and circulatory physiology 20030101 |
| Blinded test in isolated female rabbit heart reliably identifies action potential duration prolongation and proarrhythmic drugs: importance of triangulation, reverse use dependence, and instability. | Journal of cardiovascular pharmacology 20030101 |
| Coordinate induction of both cytochrome P4503A and MDR1 by St John's wort in healthy subjects. | Clinical pharmacology and therapeutics 20030101 |
| Internal standard signal suppression by co-eluting analyte in isotope dilution LC-ESI-MS. | The Analyst 20030101 |
| Lopinavir/ritonavir: a review of its use in the management of HIV infection. | Drugs 20030101 |
| Pharmacogenetics--the horizon. | Reviews in gastroenterological disorders 20030101 |
| [Effect of fexofenadine--selective antagonist of histamine receptor (H1) on histamine-induced bronchoconstriction]. | Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20030101 |
| Assessing satisfaction with desloratadine and fexofenadine in allergy patients who report dissatisfaction with loratadine. | BMC family practice 20030101 |
| Antihistamines. | Psychosomatics 20030101 |
| Issues related to monitoring the safety of over-the-counter (OTC) medicines. | Drug safety 20030101 |
| Cellular and ionic basis for the sex-related difference in the manifestation of the Brugada syndrome and progressive conduction disease phenotypes. | Journal of electrocardiology 20030101 |
| Substrate dependent inhibition profiles of fourteen drugs on CYP3A4 activity measured by a high throughput LCMS/MS method with four probe drugs, midazolam, testosterone, nifedipine and terfenadine. | Drug metabolism and pharmacokinetics 20030101 |
| Receptor-dependent regulation of the CYP3A4 gene. | Toxicology 20021227 |
| Roles of histamine in regulation of arousal and cognition: functional neuroimaging of histamine H1 receptors in human brain. | Life sciences 20021220 |
| Inhibition of allergic dermal inflammation by the novel imidazopyridazine derivative TAK-427 in a guinea pig experimental model of eczema. | The Journal of pharmacology and experimental therapeutics 20021201 |
| Inhibitory effects of oral prednisolone and fexofenadine on skin responses by prick tests with histamine and compound 48/80. | Journal of dermatological science 20021201 |
| Facial swelling and eosinophilia in a 44-year-old woman. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20021201 |
| Effects of fexofenadine on the early response to nasal allergen challenge. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20021201 |
| Effects of supratherapeutic doses of ebastine and terfenadine on the QT interval. | British journal of clinical pharmacology 20021201 |
| Effect of fexofenadine, a mast cell blocker, in infertile men with significantly increased testicular mast cells. | Asian journal of andrology 20021201 |
| Development of neuroleptic agents: pharmacogenetics and current safety issues of regulatory concern. | Dialogues in clinical neuroscience 20021201 |
| The antihistamine fexofenadine does not affect I(Kr) currents in a case report of drug-induced cardiac arrhythmia. | British journal of pharmacology 20021101 |
| Fexofenadine transport in Caco-2 cells: inhibition with verapamil and ritonavir. | Journal of clinical pharmacology 20021101 |
| Clinical pharmacology of H1-antihistamines in the skin. | The Journal of allergy and clinical immunology 20021101 |
| Comparative study of some additives for the improvement of terfenadine performance. | Die Pharmazie 20021101 |
| Ionic and cellular basis for the predominance of the Brugada syndrome phenotype in males. | Circulation 20021008 |
| Effects of fexofenadine and desloratadine on subjective and objective measures of nasal congestion in seasonal allergic rhinitis. | Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20021001 |
| Aspirin-induced urticaria and angioedema, but not bronchoconstriction, associated with cysteinyl leukotriene overproduction in 2 patients with asthma. | The Journal of allergy and clinical immunology 20021001 |
| Data-mining analyses of pharmacovigilance signals in relation to relevant comparison drugs. | European journal of clinical pharmacology 20021001 |
| Review of fexofenadine in the treatment of chronic idiopathic urticaria. | International journal of dermatology 20021001 |
| The use of handheld computers in clinical trials. | Controlled clinical trials 20021001 |
| The relationship of clinical QT prolongation to outcome in the conscious dog using a beat-to-beat QT-RR interval assessment. | The Journal of pharmacology and experimental therapeutics 20020801 |
| The functional properties of the human ether-à-go-go-like (HELK2) K+ channel. | The European journal of neuroscience 20020801 |
| Molecular identification and characterisation of the human eag2 potassium channel. | FEBS letters 20020731 |
| Simultaneous determination of fexofenadine and its related compounds by HPLC. | Journal of pharmaceutical and biomedical analysis 20020720 |
| Chronic urticaria and angioedema. | The New England journal of medicine 20020718 |
| Role of lung inflammatory mediators as a cause of exercise-induced arterial hypoxemia in young athletes. | Journal of applied physiology (Bethesda, Md. : 1985) 20020701 |
| Fexofenadine modulates T-cell function, preventing allergen-induced airway inflammation and hyperresponsiveness. | The Journal of allergy and clinical immunology 20020701 |
| Onset of action, efficacy, and safety of fexofenadine 60 mg/pseudoephedrine 120 mg versus placebo in the Atlanta allergen exposure unit. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20020701 |
| Comparison of the efficacy of combined fluticasone propionate and olopatadine versus combined fluticasone propionate and fexofenadine for the treatment of allergic rhinoconjunctivitis induced by conjunctival allergen challenge. | Clinical therapeutics 20020701 |
| In vivo anti-inflammatory effects of fexofenadine in chronic idiopathic urticaria. | Journal of the European Academy of Dermatology and Venereology : JEADV 20020701 |
| Pharmacological rescue of human K(+) channel long-QT2 mutations: human ether-a-go-go-related gene rescue without block. | Circulation 20020618 |
| Next generation antihistamines: therapeutic rationale, accomplishments and advances. | Expert opinion on investigational drugs 20020601 |
| Are herbal products dietary supplements or drugs? An important question for public safety. | Clinical pharmacology and therapeutics 20020601 |
| Effect of St John's wort on the pharmacokinetics of fexofenadine. | Clinical pharmacology and therapeutics 20020601 |
| The Rx-to-OTC switch of Claritin, Allegra, and Zyrtec: an unprecedented FDA response to petitioners and the protection of public health. | The American University law review 20020601 |
| Delineation of the protective action of zinc sulfate on ulcerative colitis in rats. | European journal of pharmacology 20020517 |
| Three-dimensional quantitative structure-activity relationship for inhibition of human ether-a-go-go-related gene potassium channel. | The Journal of pharmacology and experimental therapeutics 20020501 |
| MDR1 gene polymorphisms and disposition of the P-glycoprotein substrate fexofenadine. | British journal of clinical pharmacology 20020501 |
| Evaluation of cytokines in nasal secretions after nasal antigen challenge: lack of influence of antihistamines. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20020501 |
| [Hay fever and asthma. Many of your patients have both]. | MMW Fortschritte der Medizin 20020425 |
| Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells. | The Journal of biological chemistry 20020419 |
| [Chronic idiopathic urticaria: effectiveness of fexofenadine. A double-blind, placebo controlled study with 21 patients]. | Praxis 20020410 |
| Intradermal cholinergic agonists induce itch-associated response via M3 muscarinic acetylcholine receptors in mice. | Japanese journal of pharmacology 20020301 |
| Cardiotoxicity of new antihistamines and cisapride. | Toxicology letters 20020227 |
| Antihistamines in late-phase clinical development for allergic disease. | Expert opinion on investigational drugs 20020201 |
| Proarrhythmic potential of halofantrine, terfenadine and clofilium in a modified in vivo model of torsade de pointes. | British journal of pharmacology 20020201 |
| A double-blind, randomized, single-dose, crossover comparison of levocetirizine with ebastine, fexofenadine, loratadine, mizolastine, and placebo: suppression of histamine-induced wheal-and-flare response during 24 hours in healthy male subjects. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20020201 |
| Are antihistamines useful in managing asthma? | Current opinion in allergy and clinical immunology 20020201 |
| Determination of fexofenadine in human plasma and urine by liquid chromatography-mass spectrometry. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20020125 |
| Induction of multidrug resistance-1 and cytochrome P450 mRNAs in human mononuclear cells by rifampin. | Drug metabolism and disposition: the biological fate of chemicals 20020101 |
| Fruit juices inhibit organic anion transporting polypeptide-mediated drug uptake to decrease the oral availability of fexofenadine. | Clinical pharmacology and therapeutics 20020101 |
| Effects of antihistamines on leukotriene and cytokine release from dispersed nasal polyp cells. | Arzneimittel-Forschung 20020101 |
| Pharmacokinetic profile of zafirlukast. | Clinical pharmacokinetics 20020101 |
| Grapefruit juice reduces the oral bioavailability of fexofenadine but not desloratadine. | Clinical pharmacokinetics 20020101 |
| [Comparative antihistamine and anti-allergic effects of various antihistamine preparations]. | Terapevticheskii arkhiv 20020101 |
| Do standard doses of frequently prescribed drugs cause preventable adverse effects in women? | Journal of the American Medical Women's Association (1972) 20020101 |
| A comparison of once daily fexofenadine versus the combination of montelukast plus loratadine on domiciliary nasal peak flow and symptoms in seasonal allergic rhinitis. | Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20020101 |
| An evaluation of the effects of high-dose fexofenadine on the central nervous system: a double-blind, placebo-controlled study in healthy volunteers. | Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20020101 |
| Drug eruption and liver injury caused by terfenadine and oxatomide. | European journal of dermatology : EJD 20020101 |
| Potential cardiac toxicity of H1-antihistamines. | Clinical allergy and immunology 20020101 |
| [Risk of drug interactions. Combinations of drugs associated with ventricular arrhythmias]. | Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion 20020101 |
| [Effect of tedin on clinical and allergic indices of viral hepatitis in the presence of giardiasis]. | Meditsinskaia parazitologiia i parazitarnye bolezni 20020101 |
| Ketoconazole potentiates terfenadine-induced apoptosis in human Hep G2 cells through inhibition of cytochrome p450 3A4 activity. | Journal of cellular biochemistry 20020101 |
| Liquid chromatography/tandem mass spectrometric bioanalysis using normal-phase columns with aqueous/organic mobile phases - a novel approach of eliminating evaporation and reconstitution steps in 96-well SPE. | Rapid communications in mass spectrometry : RCM 20020101 |
| Effects of terfenadine and diphenhydramine on the CYP2D6 activity in healthy volunteers. | European journal of drug metabolism and pharmacokinetics 20020101 |
| The use of antihistamines in safety-critical jobs: a meeting report. | Current medical research and opinion 20020101 |
| Rapidly distinguishing reversible and irreversible CYP450 inhibitors by using fluorometric kinetic analyses. | European journal of drug metabolism and pharmacokinetics 20020101 |
| Inhibition of the histamine wheal by ebastine compared with cetirizine, fexofenadine and loratadine at steady state. | Drugs under experimental and clinical research 20020101 |
| Application of microtiter plate assay to evaluate inhibitory effects of various compounds on nine cytochrome P450 isoforms and to estimate their inhibition patterns. | Drug metabolism and pharmacokinetics 20020101 |
| Effects of serum albumin and liver cytosol on CYP2C9- and CYP3A4-mediated drug metabolism. | Drug metabolism and pharmacokinetics 20020101 |
| pH-metric solubility. 3. Dissolution titration template method for solubility determination. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20011201 |
| Second generation antihistamines in the treatment of seasonal allergic rhinitis due to Parietaria and cypress pollen. | Pharmacological research 20011201 |
| Histamine and the classic antihistamines. | Drug news & perspectives 20011201 |
| Assay of terfenadine in pharmaceutical formulation and human plasma by adsorptive stripping voltammetry. | Journal of pharmaceutical and biomedical analysis 20011101 |
| Fexofenadine reduces nasal congestion in perennial allergic rhinitis. | Allergy 20011101 |
| Inhibition of depolarization-induced [3H]noradrenaline release from SH-SY5Y human neuroblastoma cells by some second-generation H(1) receptor antagonists through blockade of store-operated Ca(2+) channels (SOCs). | Biochemical pharmacology 20011101 |
| [3H]dofetilide binding to HERG transfected membranes: a potential high throughput preclinical screen. | European journal of pharmacology 20011026 |
| An amino acid residue whose change by mutation affects drug binding to the HERG channel. | FEBS letters 20011012 |
| Effects of a new antiallergic drug, VUF-K-8788, on infiltration of lung parenchyma by eosinophils in guinea pigs and eosinophil-adhesion to human umbilical vein endothelial cells (HUVEC). | Biological & pharmaceutical bulletin 20011001 |
| The costs of nonsedating antihistamine therapy for allergic rhinitis in managed care: an updated analysis. | The American journal of managed care 20011001 |
| Development and evaluation of high throughput functional assay methods for HERG potassium channel. | Journal of biomolecular screening 20011001 |
| Involvement of thromboxane A2 and peptide leukotrienes in early and late phase nasal blockage in a guinea pig model of allergic rhinitis. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20010901 |
| Pharmacological characterization of the leukocyte kinetics after intranasal antigen challenge in a guinea pig model of allergic rhinitis. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20010901 |
| Terfenadine-beta-Cyclodextrin inclusion complex with antihistaminic activity enhancement. | Drug development and industrial pharmacy 20010901 |
| Ugly wait at the counter. Insurer pushes to make allergy drugs nonprescription. | Modern healthcare 20010806 |
| Effects of supratherapeutic doses of ebastine and terfenadine on the QT interval. | British journal of clinical pharmacology 20010801 |
| Identification of functionally variant MDR1 alleles among European Americans and African Americans. | Clinical pharmacology and therapeutics 20010801 |
| Assessing the effect of intranasal steroids on growth. | The Journal of allergy and clinical immunology 20010701 |
| Safety of fexofenadine in children treated for seasonal allergic rhinitis. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20010701 |
| Evaluation of the safety of fexofenadine from experience gained in general practice use in England in 1997. | European journal of clinical pharmacology 20010701 |
| [Effect of olopatadine hydrochloride, a novel antiallergic agent, on the QT interval in dogs]. | Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20010601 |
| [Seasonal allergic rhinitis. Nasal obstruction can also beh improved]. | MMW Fortschritte der Medizin 20010503 |
| The canine Purkinje fiber: an in vitro model system for acquired long QT syndrome and drug-induced arrhythmogenesis. | Journal of cardiovascular pharmacology 20010501 |
| Fexofenadine decreases sensitivity to and montelukast improves recovery from inhaled mannitol. | American journal of respiratory and critical care medicine 20010501 |
| Controlled comparison of the efficacy and safety of cetirizine 10 mg o.d. and fexofenadine 120 mg o.d. in reducing symptoms of seasonal allergic rhinitis. | International archives of allergy and immunology 20010501 |
| A descriptive analysis of the use and cost of new-generation antihistamines in the treatment of allergic rhinitis: a retrospective database analysis. | The American journal of managed care 20010501 |
| VUF-K-8788, a periphery-selective histamine H1 antagonist with anti-pruritic activities. | Japanese journal of pharmacology 20010501 |
| Roles of mast cells and histamine in mosquito bite-induced allergic itch-associated responses in mice. | Japanese journal of pharmacology 20010501 |
| Cooperativity of alpha-naphthoflavone in cytochrome P450 3A-dependent drug oxidation activities in hepatic and intestinal microsomes from mouse and human. | Xenobiotica; the fate of foreign compounds in biological systems 20010501 |
| Newer antihistamines. | The Medical letter on drugs and therapeutics 20010430 |
| Uptake and efflux of the peptidic delta-opioid receptor agonist. | Neuroscience letters 20010406 |
| Problems of heart rate correction in assessment of drug-induced QT interval prolongation. | Journal of cardiovascular electrophysiology 20010401 |
| Twenty-four hours of activity of cetirizine and fexofenadine in the skin. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20010401 |
| Drug-induced cholestasis. | Seminars in gastrointestinal disease 20010401 |
| Skin concentrations of H1-receptor antagonists. | The Journal of allergy and clinical immunology 20010301 |
| Loratadine and terfenadine interaction with nefazodone: Both antihistamines are associated with QTc prolongation. | Clinical pharmacology and therapeutics 20010301 |
| The effect of rifampin administration on the disposition of fexofenadine. | Clinical pharmacology and therapeutics 20010301 |
| Effect of hydroxyzine on the transport of etoposide in rat small intestine. | Anti-cancer drugs 20010301 |
| Fexofenadine hydrochloride--a new anti-histaminic drug. | The Israel Medical Association journal : IMAJ 20010301 |
| Pharmacokinetic and safety profile of desloratadine and fexofenadine when coadministered with azithromycin: a randomized, placebo-controlled, parallel-group study. | Clinical therapeutics 20010301 |
| Role of mast cells in antigen-induced airway inflammation and bronchial hyperresponsiveness in rats. | Japanese journal of pharmacology 20010301 |
| Inhibition of human CYP1A2 activity in vitro by methylxanthines: potent competitive inhibition by 8-phenyltheophylline. | Xenobiotica; the fate of foreign compounds in biological systems 20010301 |
| Fixed solar urticaria to visible light successfully treated with fexofenadine. | Photodermatology, photoimmunology & photomedicine 20010201 |
| Absence of nasal mucosal atrophy with fluticasone aqueous nasal spray. | Archives of otolaryngology--head & neck surgery 20010201 |
| Involvement of multiple human cytochromes P450 in the liver microsomal metabolism of astemizole and a comparison with terfenadine. | British journal of clinical pharmacology 20010201 |
| Multicenter study of the efficacy and safety of fexofenadine 60 mg. twice daily in 108 Thai patients with chronic idiopathic urticaria. | Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20010201 |
| Premedication with antihistamines may enhance efficacy of specific-allergen immunotherapy. | The Journal of allergy and clinical immunology 20010101 |
| Comparison of montelukast and fexofenadine for chronic idiopathic urticaria. | Archives of dermatology 20010101 |
| Suppression of the early and late cutaneous allergic responses using fexofenadine and montelukast. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20010101 |
| Safety of antihistamines in children. | Drug safety 20010101 |
| Design, synthesis and antihistaminic (H1)activity of some condensed 2-(substituted)arylaminoethylpyrimidin-4(3H)-ones. | Arzneimittel-Forschung 20010101 |
| Histamine-induced activation of human lung macrophages. | International archives of allergy and immunology 20010101 |
| Saquinavir soft gelatin capsule: a comparative safety review. | Drug safety 20010101 |
| Evaluation of drug-induced QT interval prolongation: implications for drug approval and labelling. | Drug safety 20010101 |
| Pharmacokinetic/pharmacodynamic assessment of the effects of E4031, cisapride, terfenadine and terodiline on monophasic action potential duration in dog. | Xenobiotica; the fate of foreign compounds in biological systems 20010101 |
| [The effect of second generation histamine antagonists on the heart]. | Pneumonologia i alergologia polska 20010101 |
| Delusion of worm infestation associated with clarithromycin in a patient on peritoneal dialysis. | Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 20010101 |
| Dissociable effects of histamine H1 antagonists on reaction-time performance in rats. | Pharmacology, biochemistry, and behavior 20010101 |
| Impact of rhinitis on airway inflammation: biological and therapeutic implications. | Respiratory research 20010101 |
| Effect of oxatomide, an antiallergic agent, on QT interval in dogs. | Arzneimittel-Forschung 20010101 |
| [Efficacy and safety of fexofenadine and cetirizine in the treatment of allergic rhinitis]. | Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993) 20010101 |
| Antihistamines and the torsade de point in children with allergic rhinitis. | European review for medical and pharmacological sciences 20010101 |
| Emerging role of drug interaction studies in drug development: the good, the bad, and the unknown. | Psychopharmacology bulletin 20010101 |
| Pharmacological blockade of ERG K(+) channels and Ca(2+) influx through store-operated channels exerts opposite effects on intracellular Ca(2+) oscillations in pituitary GH(3) cells. | Molecular pharmacology 20001101 |
| A structural basis for drug-induced long QT syndrome. | Proceedings of the National Academy of Sciences of the United States of America 20001024 |
| Mechanism of terfenadine block of ATP-sensitive K(+) channels. | British journal of pharmacology 20000801 |
| Redox state dependency of HERGS631C channel pharmacology: relation to C-type inactivation. | FEBS letters 20000526 |
| Fexofenadine HCl is safe and effective for treatment of chronic idiopathic urticaria. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20000501 |
| Sedation with 'non-sedating' antihistamines: four prescription-event monitoring studies in general practice. | BMJ (Clinical research ed.) 20000429 |
| Severe cardiac arrhythmia on fexofenadine? | Prescrire international 20000201 |
| Loratadine blockade of K(+) channels in human heart: comparison with terfenadine under physiological conditions. | The Journal of pharmacology and experimental therapeutics 20000101 |
| Antiallergic effects of H1-receptor antagonists. | Allergy 20000101 |
| Specific inhibition of TH2-type cytokine production from human peripheral T cells by terfenadine in vitro. | Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 19990901 |
| Fexofenadine and prolonged QT intervals. | Nursing 19990901 |
| Epinastine, a nonsedating histamine H1 receptor antagonist, has a negligible effect on HERG channel. | European journal of pharmacology 19990625 |
| Block of HERG potassium channels by the antihistamine astemizole and its metabolites desmethylastemizole and norastemizole. | Journal of cardiovascular electrophysiology 19990601 |
| Interplay between CYP3A-mediated metabolism and polarized efflux of terfenadine and its metabolites in intestinal epithelial Caco-2 (TC7) cell monolayers. | Pharmaceutical research 19990501 |
| QT lengthening and life-threatening arrhythmias associated with fexofenadine. | Lancet (London, England) 19990320 |
| Risk of ventricular arrhythmias associated with nonsedating antihistamine drugs. | British journal of clinical pharmacology 19990301 |
| Blockade of HERG and Kv1.5 by ketoconazole. | The Journal of pharmacology and experimental therapeutics 19980801 |
| Molecular basis for the lack of HERG K+ channel block-related cardiotoxicity by the H1 receptor blocker cetirizine compared with other second-generation antihistamines. | Molecular pharmacology 19980701 |
| Fexofenadine. | Drugs 19980201 |
| A mechanism for the proarrhythmic effects of cisapride (Propulsid): high affinity blockade of the human cardiac potassium channel HERG. | FEBS letters 19971103 |
| [Excessive terfenadine level due to drinking grapefruit juice]. | Nederlands tijdschrift voor geneeskunde 19971011 |
| Applications of primary human hepatocytes in the evaluation of pharmacokinetic drug-drug interactions: evaluation of model drugs terfenadine and rifampin. | Cell biology and toxicology 19970701 |
| Comparative effects of nonsedating histamine H1 receptor antagonists, ebastine and terfenadine, on human Kv1.5 channels. | European journal of pharmacology 19970520 |
| [Syncopes during simultaneous use of terfenadine and itraconazole]. | Nederlands tijdschrift voor geneeskunde 19970510 |
| A comparative pharmacokinetic-pharmacodynamic study of the electrocardiographic effects of epinastine and terfenadine in rats. | The Journal of pharmacy and pharmacology 19970401 |
| Selective biotransformation of the human immunodeficiency virus protease inhibitor saquinavir by human small-intestinal cytochrome P4503A4: potential contribution to high first-pass metabolism. | Drug metabolism and disposition: the biological fate of chemicals 19970201 |
| Torsades de pointes from terfenadine and sotalol given in combination. | Pacing and clinical electrophysiology : PACE 19961001 |
| Terfenadine induced coma mimicking structural brain disease. | The Journal of the Association of Physicians of India 19961001 |
| Terfenadine-induced cholestatic hepatitis. | Lancet (London, England) 19960824 |
| HERG, a primary human ventricular target of the nonsedating antihistamine terfenadine. | Circulation 19960815 |
| Blockade of HERG channels expressed in Xenopus oocytes by the histamine receptor antagonists terfenadine and astemizole. | FEBS letters 19960429 |
| Terfenadine overdose induced polymorphous ventricular tachycardia. | Indian pediatrics 19951001 |
| Probable terfenadine-fluoxetine-associated cardiac toxicity. | The Annals of pharmacotherapy 19950901 |
| Effect of terfenadine and budesonide on nasal symptoms, olfaction, and nasal airway patency following allergen challenge. | Allergy 19950801 |
| [Ventricular arrhythmia induced by terfenadine treatment]. | Medicina clinica 19950204 |
| Torsades de pointes associated with terfenadine in a case of liver cirrhosis and hepatocellular carcinoma. | Internal medicine (Tokyo, Japan) 19950201 |
| Torsades de pointes induced by erythromycin and terfenadine. | The American journal of emergency medicine 19941101 |
| Torsades de pointes ventricular tachycardia associated with terfenadine and paracetamol self medication. | The New Zealand medical journal 19941012 |
| Torsade de pointes induced by terfenadine in a patient with long QT syndrome. | Journal of electrocardiology 19941001 |
| Urinary retention as a result of administration of terfenadine. | The Journal of allergy and clinical immunology 19940601 |
| Benefit/risk ratio of the antihistamines (H1-receptor antagonists) terfenadine and chlorpheniramine in children. | The Journal of pediatrics 19940601 |
| Risk of developing life-threatening ventricular arrhythmia associated with tefenadine in comparison with over-the-counter antihistamines, ibuprofen and clemastine. | The American journal of cardiology 19940215 |
| Characteristics of P388/VMDRC.04, a simple, sensitive model for studying P-glycoprotein antagonists. | Cancer research 19940201 |
| Drug-induced torsades de pointes: a possible interaction of terfenadine and erythromycin. | The Annals of pharmacotherapy 19940201 |
| [Torsades de pointes caused by the association of terfenadine and erythromycin]. | Annales de medecine interne 19940101 |
| Torsades de pointes associated with astemizole (Hismanal) therapy. | Archives of internal medicine 19931213 |
| Potential terfenadine-fluoxetine interaction. | The Annals of pharmacotherapy 19931101 |
| Public health problems and the rapid estimation of the size of the population at risk. Torsades de pointes and the use of terfenadine and astemizole in The Netherlands. | Pharmacy world & science : PWS 19931015 |
| Syncope and cardiac arrhythmia due to an interaction between itraconazole and terfenadine. | The American journal of medicine 19931001 |
| Is QT interval prolongation harmful? A regulatory perspective. | The American journal of cardiology 19930826 |
| The effect of antihistamines on the immediate allergic response: a comparative review. | Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 19930601 |
| Cutaneous IgE-mediated inflammatory lesion size is inhibited by an H1 antagonist (terfenadine) while mediator release is unaffected in vivo and in vitro. | Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 19930501 |
| [A new cause of torsades de pointes: combination of terfenadine and troleandomycin]. | Annales de cardiologie et d'angeiologie 19930501 |
| Terfenadine-induced tremor. | Annals of neurology 19930201 |
| Torsades de pointes after terfenadine-itraconazole interaction. | BMJ (Clinical research ed.) 19930116 |
| Erythromycin and ketoconazole (Nizoral) associated with terfenadine (Seldane)-induced ventricular arrhythmias. | General dentistry 19930101 |
| The effect of terfenadine on the immediate and late-phase reactions mediated by immunoglobulin E. | International archives of allergy and immunology 19930101 |
| [Treatment with terfenadine and ketoconazole or itraconazole can cause torsades de pointes ventricular tachycardia]. | Duodecim; laaketieteellinen aikakauskirja 19930101 |
| Torsades de Pointes after treatment with terfenadine and ketoconazole. | European heart journal 19920701 |
| Terfenadine use associated with ventricular dysrhythmias. | Critical care nurse 19920201 |
| Torsades de pointes occurring in association with terfenadine use. | JAMA 19901205 |
| Antihistaminic activity and side effect profile of epinastine and terfenadine in healthy volunteers. | International journal of clinical pharmacology, therapy, and toxicology 19901201 |
| Effects of azatadine, terfenadine, and astemizole on allergen-induced nasal provocation. | Annals of allergy 19900201 |
| Prolongation of simple and choice reaction times in a double-blind comparison of twice-daily hydroxyzine versus terfenadine. | The Journal of allergy and clinical immunology 19890901 |
| [Therapy of acute and chronic urticaria and of Quincke's edema]. | Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis 19890516 |
| Comparative study of astemizole and terfenadine in the treatment of chronic idiopathic urticaria. A randomized double-blind study of 40 patients. | Annals of allergy 19890401 |
| 'In vivo' and 'in vitro' evaluation of four antihistamines (astemizole, azatadine, mequitazine, terfenadine). | Allergologia et immunopathologia 19890101 |
| A comparison of acrivastine versus terfenadine and placebo in the treatment of chronic idiopathic urticaria. | The Journal of international medical research 19890101 |
| Evaluation of the antimuscarinic activity of atropine, terfenadine and mequitazine in healthy volunteers. | British journal of clinical pharmacology 19880101 |
| Pharmacologic analysis of LY188695 (KB-2413), 1-(2-ethoxyethyl)-2-(4-methyl-1-homopiperazinyl)-benzimidazole difumarate, a potent histamine1 receptor antagonist. | Agents and actions 19870201 |
| Double-blind comparison of astemizole and terfenadine in the treatment of chronic urticaria. | Pharmatherapeutica 19860101 |
| [Comparison of astemizole and terfenadine in the treatment of chronic urticaria. A randomized double-blind study of 40 patients]. | Zeitschrift fur Hautkrankheiten 19850101 |
| Clinical pharmacokinetics of H1-receptor antagonists (the antihistamines). | Clinical pharmacokinetics 19850101 |