Aminohippurate sodium
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Changes in expression of renal Oat1, Oat3 and Mrp2 in cisplatin-induced acute renal failure after treatment of JBP485 in rats. | Toxicology and applied pharmacology 20121101 |
α-Ketoglutarate-related inhibitors of HIF prolyl hydroxylases are substrates of renal organic anion transporters 1 (OAT1) and 4 (OAT4). | Pflugers Archiv : European journal of physiology 20121001 |
Effect of sulfhydryl modification on rat kidney basolateral plasma membrane transport function. | Bulletin of environmental contamination and toxicology 20121001 |
Renal hemodynamic response to L-arginine in uncomplicated, type 1 diabetes mellitus: the role of buffering anions and tubuloglomerular feedback. | American journal of physiology. Renal physiology 20120901 |
Renal effects of carprofen and etodolac in euvolemic and volume-depleted dogs. | American journal of veterinary research 20120901 |
Attenuated glomerular arginine transport prevents hyperfiltration and induces HIF-1α in the pregnant uremic rat. | American journal of physiology. Renal physiology 20120801 |
A novel approach for blood purification: mixed-matrix membranes combining diffusion and adsorption in one step. | Acta biomaterialia 20120701 |
Transepithelial transport of 4-chloro-2-methylphenoxyacetic acid (MCPA) across human intestinal Caco-2 cell monolayers. | Basic & clinical pharmacology & toxicology 20120601 |
A Na+-phosphate cotransporter homologue (SLC17A4 protein) is an intestinal organic anion exporter. | American journal of physiology. Cell physiology 20120601 |
Interaction and transport of kynurenic acid via human organic anion transporters hOAT1 and hOAT3. | Pharmacological research 20120201 |
First evidence of epithelial transport in tardigrades: a comparative investigation of organic anion transport. | The Journal of experimental biology 20120201 |
A structural and spectroscopic study on para-aminohippuric acid with experimental and theoretical approaches. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20120101 |
Renal expression and function of oat1 and oat3 in rats with vascular calcification. | Pharmacology 20120101 |
Metabonomics biomarkers for subacute toxicity screening for benzene exposure in mice. | Journal of toxicology and environmental health. Part A 20120101 |
Differential interaction of dicarboxylates with human sodium-dicarboxylate cotransporter 3 and organic anion transporters 1 and 3. | American journal of physiology. Renal physiology 20111101 |
Short-term effects of tolvaptan on renal function and volume in patients with autosomal dominant polycystic kidney disease. | Kidney international 20110801 |
Interaction of hydroxycinnamic acids and their conjugates with organic anion transporters and ATP-binding cassette transporters. | Molecular nutrition & food research 20110701 |
Functional analysis of human sodium-phosphate transporter 4 (NPT4/SLC17A3) polymorphisms. | Journal of pharmacological sciences 20110101 |
Inhibitory effect of caffeic acid on human organic anion transporters hOAT1 and hOAT3: a novel candidate for food-drug interaction. | Drug metabolism and pharmacokinetics 20110101 |
Contribution of bradykinin B2 receptors to the inhibition by valsartan of systemic and renal effects of exogenous angiotensin II in salt-repleted humans. | The Journal of pharmacology and experimental therapeutics 20100901 |
Development and validation of a liquid chromatography-tandem mass spectrometry method for simultaneous quantification of p-aminohippuric acid and inulin in rat plasma for renal function study. | Analytical and bioanalytical chemistry 20100901 |
Glomerular hyperfiltration and increased proximal sodium reabsorption in subjects with type 2 diabetes or impaired fasting glucose in a population of the African region. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20100701 |
Determination of p-aminohippuric acid in rat plasma by liquid chromatography-tandem mass spectrometry. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100601 |
Plasma 25-hydroxyvitamin D and regulation of the renin-angiotensin system in humans. | Hypertension (Dallas, Tex. : 1979) 20100501 |
Establishment and characterization of Mardin-Darby canine kidney cells stably expressing human organic anion transporters. | Archives of pharmacal research 20100501 |
Measurement of kidney perfusion by magnetic resonance imaging: comparison of MRI with arterial spin labeling to para-aminohippuric acid plasma clearance in male subjects with metabolic syndrome. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20100401 |
Major contribution of tubular secretion to creatinine clearance in mice. | Kidney international 20100301 |
Effects of dl-2-hydroxy-4-methylthiobutyrate on the first-pass intestinal metabolism of dietary methionine and its extra-intestinal availability. | The British journal of nutrition 20100301 |
Dopamine increases renal oxygenation: a clinical study in post-cardiac surgery patients. | Acta anaesthesiologica Scandinavica 20100201 |
Differential effects of clinical doses of antenatal betamethasone on nephron endowment and glomerular filtration rate in adult sheep. | Reproductive sciences (Thousand Oaks, Calif.) 20100201 |
Renal functional effects of simultaneous bilateral single-tract percutaneous access in pigs. | BJU international 20100101 |
Inhibitory effect of selective cyclooxygenase-2 inhibitor lumiracoxib on human organic anion transporters hOAT1 and hOAT3. | Drug metabolism and pharmacokinetics 20100101 |
Lack of a primary physicochemical determinant in the direct transport of drugs to the brain after nasal administration in rats: potential involvement of transporters in the pathway. | Drug metabolism and pharmacokinetics 20100101 |
Low-dose indomethacin after ischemic acute kidney injury prevents downregulation of Oat1/3 and improves renal outcome. | American journal of physiology. Renal physiology 20091201 |
Decreased urinary secretion of belotecan in folic acid-induced acute renal failure rats due to down-regulation of Oat1 and Bcrp. | Xenobiotica; the fate of foreign compounds in biological systems 20091001 |
Multiple efflux pumps are involved in the transepithelial transport of colchicine: combined effect of p-glycoprotein and multidrug resistance-associated protein 2 leads to decreased intestinal absorption throughout the entire small intestine. | Drug metabolism and disposition: the biological fate of chemicals 20091001 |
Molecular evidence for an involvement of organic anion transporters (OATs) in aristolochic acid nephropathy. | Toxicology 20091001 |
Determination of para-aminohippuric acid (PAH) in human plasma and urine by liquid chromatography-tandem mass spectrometry. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20091001 |
Organic anion transporter OAT1 is involved in renal handling of citrulline. | American journal of physiology. Renal physiology 20090701 |
Oral contraceptive progestins and angiotensin-dependent control of the renal circulation in humans. | Journal of human hypertension 20090601 |
Roles of inner blood-retinal barrier organic anion transporter 3 in the vitreous/retina-to-blood efflux transport of p-aminohippuric acid, benzylpenicillin, and 6-mercaptopurine. | The Journal of pharmacology and experimental therapeutics 20090401 |
Effect of CP-690,550, an orally active janus kinase inhibitor, on renal function in healthy adult volunteers. | Journal of clinical pharmacology 20090401 |
Dietary fats altered nephrotoxicity profile of methylmercury in rats. | Journal of applied toxicology : JAT 20090301 |
Regulation of human organic anion transporter 1 by ANG II: involvement of protein kinase Calpha. | American journal of physiology. Endocrinology and metabolism 20090201 |
Renal vascular endothelial function in hypertensive patients with type 2 diabetes mellitus. | American journal of kidney diseases : the official journal of the National Kidney Foundation 20090201 |
Involvement of Mrp2/MRP2 in the species different excretion route of benzylpenicillin between rat and human. | Xenobiotica; the fate of foreign compounds in biological systems 20090201 |
Expression and functional characterization of choline transporter in human keratinocytes. | Journal of pharmacological sciences 20090101 |
[Coupling of Na+/alpha-ketoglutarate symport and PAH/alpha-ketoglutarate antiport in epithelial cells. Estimation of probability of the anion exchanger spontaneous re-orientation]. | Zhurnal evoliutsionnoi biokhimii i fiziologii 20090101 |
The flavonoid quercetin protects and prevents against potassium dichromate-induced systemic peroxidation of lipids and diminution in renal clearance of para-aminohippuric acid and inulin in the rat. | Drug and chemical toxicology 20090101 |
Organic anion transporters OAT1 and OAT4 mediate the high affinity transport of glutarate derivatives accumulating in patients with glutaric acidurias. | Pflugers Archiv : European journal of physiology 20081001 |
Texas Red transport across rat and dogfish shark (Squalus acanthias) choroid plexus. | American journal of physiology. Regulatory, integrative and comparative physiology 20081001 |
Nutrient net absorption across the portal-drained viscera of forage-fed beef steers: Quantitative assessment and application to a nutritional prediction model. | Journal of animal science 20080901 |
Cell free expression and functional reconstitution of eukaryotic drug transporters. | Biochemistry 20080415 |
Inhibition of carrier-mediated uptake of epirubicin reduces cytotoxicity in primary culture of rat hepatocytes. | Journal of applied toxicology : JAT 20080401 |
Overlapping in vitro and in vivo specificities of the organic anion transporters OAT1 and OAT3 for loop and thiazide diuretics. | American journal of physiology. Renal physiology 20080401 |
Functional analysis of phenolsulfonphthalein transport system in Long-Evans Cinnamon rats. | Biochimica et biophysica acta 20080101 |
Upregulation of rat renal cortical organic anion transporter (OAT1 and OAT3) expression in response to ischemia/reperfusion injury. | American journal of nephrology 20080101 |
Segment-specific proximal tubule injury in tripterygium glycosides intoxicated rats. | Journal of biochemical and molecular toxicology 20080101 |
Multiple human isoforms of drug transporters contribute to the hepatic and renal transport of olmesartan, a selective antagonist of the angiotensin II AT1-receptor. | Drug metabolism and disposition: the biological fate of chemicals 20071201 |
The effect of oral contraceptives on the nitric oxide system and renal function. | American journal of physiology. Renal physiology 20071101 |
Rat organic solute carrier protein 1 (rOscp1) mediated the transport of organic solutes in Xenopus laevis oocytes: isolation and pharmacological characterization of rOscp1. | Life sciences 20070922 |
Possible involvement of organic anion and cation transporters in renal excretion of xanthine derivatives, 3-methylxanthine and enprofylline. | Life sciences 20070922 |
Involvement of carrier-mediated transport system in uptake of tetrodotoxin into liver tissue slices of puffer fish Takifugu rubripes. | Toxicon : official journal of the International Society on Toxinology 20070801 |
In situ kinetic modelling of intestinal efflux in rats: functional characterization of segmental differences and correlation with in vitro results. | Biopharmaceutics & drug disposition 20070701 |
Cl- -dependent upregulation of human organic anion transporters: different effects on transport kinetics between hOAT1 and hOAT3. | American journal of physiology. Renal physiology 20070701 |
Isolation and characterization of polyspecific mouse organic solute carrier protein 1 (mOscp1). | Drug metabolism and disposition: the biological fate of chemicals 20070701 |
Alteration in renal organic anion transporter 1 after ischemia/reperfusion in cadaveric renal allografts. | The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 20070601 |
Downregulation of organic anion transporters OAT1 and OAT3 correlates with impaired secretion of para-aminohippurate after ischemic acute renal failure in rats. | American journal of physiology. Renal physiology 20070501 |
Effects of brimonidine ingestion on cardiovascular responses and renal function in conscious dogs. | Veterinary research communications 20070401 |
Characterization of the uptake of organic anion transporter (OAT) 1 and OAT3 substrates by human kidney slices. | The Journal of pharmacology and experimental therapeutics 20070401 |
Progesterone inhibits folic acid transport in human trophoblasts. | The Journal of membrane biology 20070401 |
Simultaneous determination of p-aminobenzoic acid and its metabolites in the urine of volunteers, treated with p-aminobenzoic acid sunscreen formulation. | Journal of pharmaceutical and biomedical analysis 20070312 |
Ifosfamide toxicity in cultured proximal renal tubule cells. | Pediatric nephrology (Berlin, Germany) 20070301 |
The putative transmembrane segment 7 of human organic anion transporter hOAT1 dictates transporter substrate binding and stability. | The Journal of pharmacology and experimental therapeutics 20070301 |
Downregulation of organic anion transporters in rat kidney under ischemia/reperfusion-induced acute [corrected] renal failure. | Kidney international 20070301 |
On-line automatic SPE-CE coupling for the determination of biological markers in urine. | Electrophoresis 20070301 |
Decreased renal transplant function after parathyroidectomy. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20070201 |
Renal proximal tubule segment-specific nephrotoxicity: an overview on biomarkers and histopathology. | Toxicologic pathology 20070201 |
Determination of the external loops and the cellular orientation of the N- and the C-termini of the human organic anion transporter hOAT1. | The Biochemical journal 20070115 |
Efflux of drugs and solutes from brain: the interactive roles of diffusional transcapillary transport, bulk flow and capillary transporters. | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20070101 |
Difference between pharmacokinetics of mycophenolic acid (MPA) in rats and that in humans is caused by different affinities of MRP2 to a glucuronized form. | Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20070101 |
Absorption of folate by Caco-2 cells is not affected by high glucose concentration. | European journal of pharmacology 20061203 |
Prorenin and angiotensin-dependent renal vasoconstriction in type 1 and type 2 diabetes. | Journal of the American Society of Nephrology : JASN 20061201 |
Differences in decline in GFR with age between males and females. Reference data on clearances of inulin and PAH in potential kidney donors. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060901 |
Application of the isolated perfused rat kidney model to assess gender effects on drug excretion. | Drug development and industrial pharmacy 20060901 |
Reducing shock number dramatically decreases lesion size in a juvenile kidney model. | Journal of endourology 20060901 |
Transport of estrone sulfate by the novel organic anion transporter Oat6 (Slc22a20). | American journal of physiology. Renal physiology 20060801 |
Renal elimination of p-aminohippurate (PAH) in response to three days of biliary obstruction in the rat. The role of OAT1 and OAT3. | Biochimica et biophysica acta 20060701 |
Mechanism of L-ascorbic acid uptake by rabbit corneal epithelial cells: evidence for the involvement of sodium-dependent vitamin C transporter 2. | Current eye research 20060601 |
Characterization of prostaglandin E1 transport in rat renal brush-border membrane. | Drug metabolism and pharmacokinetics 20060601 |
Interaction of zalcitabine with human organic anion transporter 1. | Die Pharmazie 20060501 |
Hepatic metabolism of 2-hydroxy-4-methylthiobutyrate in growing lambs. | Journal of dairy science 20060301 |
Decreased renal organic anion secretion and plasma accumulation of endogenous organic anions in OAT1 knock-out mice. | The Journal of biological chemistry 20060224 |
The course of diabetic glomerulopathy in patients with type I diabetes: a 6-year follow-up with serial biopsies. | Kidney international 20060201 |
The use of mammalian cortical kidney slices for the study of tubule secretion: a pioneering step toward understanding organic anion transport. | American journal of physiology. Renal physiology 20060101 |
Pharmacokinetic and pharmacodynamic parameters of ramipril and ramiprilat in healthy dogs and dogs with reduced glomerular filtration rate. | Journal of veterinary internal medicine 20060101 |
Organic anion transporter family: current knowledge. | Journal of pharmacological sciences 20060101 |
Functional expression of the rat organic anion transporter 1 (rOAT1) in Saccharomyces cerevisiae. | Biochimica et biophysica acta 20051230 |
Early detection of progressive renal dysfunction in patients with coronary artery disease. | Kidney international 20051201 |
Simple HPLC-UV method for determination of iohexol, iothalamate, p-aminohippuric acid and n-acetyl-p-aminohippuric acid in human plasma and urine with ERPF, GFR and ERPF/GFR ratio determination using colorimetric analysis. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20051105 |
Handling of the homocysteine S-conjugate of methylmercury by renal epithelial cells: role of organic anion transporter 1 and amino acid transporters. | The Journal of pharmacology and experimental therapeutics 20051101 |
Transepithelial urate transport by avian renal proximal tubule epithelium in primary culture. | The Journal of experimental biology 20051101 |
Intestinal renal metabolism of L-citrulline and L-arginine following enteral or parenteral infusion of L-alanyl-L-[2,15N]glutamine or L-[2,15N]glutamine in mice. | American journal of physiology. Gastrointestinal and liver physiology 20051001 |
Handling of cysteine S-conjugates of methylmercury in MDCK cells expressing human OAT1. | Kidney international 20051001 |
Isolation and functional characterization of a novel organic solute carrier protein, hOSCP1. | The Journal of biological chemistry 20050916 |
A compartmental capillary, convolution integration model to investigate nutrient transport and metabolism in vivo from paired indicator/nutrient dilution curves. | Journal of applied physiology (Bethesda, Md. : 1985) 20050901 |
Transport of N-acetylcysteine s-conjugates of methylmercury in Madin-Darby canine kidney cells stably transfected with human isoform of organic anion transporter 1. | The Journal of pharmacology and experimental therapeutics 20050901 |
Renin release in response to Renin system blockade: activation of the Renin system in type 1 diabetes mellitus. | Journal of the renin-angiotensin-aldosterone system : JRAAS 20050901 |
Structure-affinity relationship in the interactions of human organic anion transporter 1 with caffeine, theophylline, theobromine and their metabolites. | Biochimica et biophysica acta 20050815 |
Functional consequences of single nucleotide polymorphisms in the human organic anion transporter hOAT1 (SLC22A6). | The Journal of pharmacology and experimental therapeutics 20050801 |
A summary of recent findings on birth outcomes and developmental effects of prenatal ETS, PAH, and pesticide exposures. | Neurotoxicology 20050801 |
Determination of uric acid and p-aminohippuric acid in human saliva and urine using capillary electrophoresis with electrochemical detection: potential application in fast diagnosis of renal disease. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050725 |
Immunocytochemical characterization of the incubated rat renal cortical slices. | Pflugers Archiv : European journal of physiology 20050701 |
Co-localization and interaction of organic anion transporter 1 with caveolin-2 in rat kidney. | Experimental & molecular medicine 20050630 |
Interactions of stevioside and steviol with renal organic anion transporters in S2 cells and mouse renal cortical slices. | Pharmaceutical research 20050601 |
Functional expression of pig renal organic anion transporter 3 (pOAT3). | Biochimie 20050501 |
Altered renal elimination of organic anions in rats with chronic renal failure. | Biochimica et biophysica acta 20050415 |
Differential contributions of rOat1 (Slc22a6) and rOat3 (Slc22a8) to the in vivo renal uptake of uremic toxins in rats. | Pharmaceutical research 20050401 |
Molecular cloning and functional analyses of OAT1 and OAT3 from cynomolgus monkey kidney. | Pharmaceutical research 20050401 |
Functional analysis of polymorphisms in the organic anion transporter, SLC22A6 (OAT1). | Pharmacogenetics and genomics 20050401 |
Reduced plasma total homocysteine concentrations in Type 1 diabetes mellitus is determined by increased renal clearance. | Diabetic medicine : a journal of the British Diabetic Association 20050301 |
Characterization of secretory intestinal transport of phenolsulfonphthalein. | Drug metabolism and pharmacokinetics 20050201 |
Segmentary effects on the renal proximal tubule due to hexachloro-1,3-butadiene in rats: biomarkers related to gender. | Journal of applied toxicology : JAT 20050101 |
Involvement of multiple transporters in the efflux of 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors across the blood-brain barrier. | The Journal of pharmacology and experimental therapeutics 20041201 |
Regulation of renal adenosine excretion in humans--role of sodium and fluid homeostasis. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20041101 |
Contribution of multidrug resistance protein 2 (MRP2/ABCC2) to the renal excretion of p-aminohippurate (PAH) and identification of MRP4 (ABCC4) as a novel PAH transporter. | Journal of the American Society of Nephrology : JASN 20041101 |
Different transport properties between famotidine and cimetidine by human renal organic ion transporters (SLC22A). | European journal of pharmacology 20041025 |
The legacy of Homer W. Smith: mechanistic insights into renal physiology. | The Journal of clinical investigation 20041015 |
Vagal cooling and concomitant portal norepinephrine infusion do not reduce net hepatic glucose uptake in conscious dogs. | American journal of physiology. Regulatory, integrative and comparative physiology 20041001 |
Characterization of renal excretion mechanism for a novel diuretic, M17055, in rats. | Journal of pharmaceutical sciences 20041001 |
Protective effect of resveratrol against 6-hydroxydopamine-induced impairment of renal p-aminohippurate transport. | Archives of toxicology 20040901 |
The renal-specific transporter mediates facilitative transport of organic anions at the brush border membrane of mouse renal tubules. | Journal of the American Society of Nephrology : JASN 20040801 |
Homocysteine and the renal epithelial transport and toxicity of inorganic mercury: role of basolateral transporter organic anion transporter 1. | Journal of the American Society of Nephrology : JASN 20040801 |
Human organic anion transporter 1 mediates cellular uptake of cysteine-S conjugates of inorganic mercury. | Kidney international 20040701 |
Renal secretion of the antiviral nucleoside analog AM188 is inhibited by probenecid, p-aminohippuric acid, and cimetidine in the isolated perfused rat kidney. | Pharmaceutical research 20040601 |
Severe hyperglycemia: a determinant factor for hypofiltration in alloxan diabetic rats. | Acta diabetologica 20040601 |
Measurement of glomerular filtration rate, renal plasma flow, and endogenous creatinine clearance in cheetahs (Acinonyx jubatus jubatus). | Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians 20040601 |
Cysteine residues in the organic anion transporter mOAT1. | The Biochemical journal 20040515 |
Organic anion transport in choroid plexus from wild-type and organic anion transporter 3 (Slc22a8)-null mice. | American journal of physiology. Renal physiology 20040501 |
Renal elimination of organic anions in rats with bilateral ureteral obstruction. | Biochimica et biophysica acta 20040405 |
Action of EGF and PGE2 on basolateral organic anion uptake in rabbit proximal renal tubules and hOAT1 expressed in human kidney epithelial cells. | American journal of physiology. Renal physiology 20040401 |
Expression studies and functional characterization of renal human organic anion transporter 1 isoforms. | Drug metabolism and disposition: the biological fate of chemicals 20040401 |
ARF in children with minimal change nephrotic syndrome may be related to functional changes of the glomerular basal membrane. | American journal of kidney diseases : the official journal of the National Kidney Foundation 20040301 |
Human organic anion transporter 4 is a renal apical organic anion/dicarboxylate exchanger in the proximal tubules. | Journal of pharmacological sciences 20040301 |
A new HPLC method to determine glomerular filtration rate and effective renal plasma flow in conscious dogs by single intravenous administration of iohexol and p-aminohippuric acid. | Journal of chromatographic science 20040201 |
Interaction of the metal chelator DMPS with OAT1 and OAT3 in intact isolated rabbit renal proximal tubules. | American journal of physiology. Renal physiology 20040101 |
Characterization of uremic toxin transport by organic anion transporters in the kidney. | Kidney international 20040101 |
Subpressor dose asymmetric dimethylarginine modulates renal function in humans through nitric oxide synthase inhibition. | Kidney & blood pressure research 20040101 |
On the role of the kidneys in the pathogenesis of edema formation during permanent morphine application/an experimental study in rats. | Arzneimittel-Forschung 20040101 |
Peroxisome proliferator-activated receptor [gamma] agonist provides superior renal protection versus angiotensin-converting enzyme inhibition in a rat model of type 2 diabetes with obesity. | The Journal of pharmacology and experimental therapeutics 20031201 |
Effect of chronic accumulation of aluminum on renal function, cortical renal oxidative stress and cortical renal organic anion transport in rats. | Archives of toxicology 20031101 |
Stoichiometry of organic anion/dicarboxylate exchange in membrane vesicles from rat renal cortex and hOAT1-expressing cells. | American journal of physiology. Renal physiology 20031001 |
Protein kinase C activation downregulates human organic anion transporter 1-mediated transport through carrier internalization. | Journal of the American Society of Nephrology : JASN 20030801 |
Identification of a novel voltage-driven organic anion transporter present at apical membrane of renal proximal tubule. | The Journal of biological chemistry 20030725 |
Contribution of organic anion transporter 3 (Slc22a8) to the elimination of p-aminohippuric acid and benzylpenicillin across the blood-brain barrier. | The Journal of pharmacology and experimental therapeutics 20030701 |
Nonionic contrast media are less nephrotoxic than ionic contrast media to rat renal cortical slices. | Toxicology letters 20030605 |
Compensation increase in organic anion excretion in rats with acute biliary obstruction: role of the renal organic anion transporter 1. | Pharmacology 20030601 |
Vasodilator effects of L-arginine are stereospecific and augmented by insulin in humans. | American journal of physiology. Endocrinology and metabolism 20030601 |
Effects of a therapy with losartan and quinaprilat on the progression of chronic renal failure in rats after a single dose of uranyl nitrate or 5/6 nephrectomy. | Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20030601 |
Use of gene chip technology for the characterisation of the regulation of renal transport processes and of nephrotoxicity in rats. | Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20030601 |
Inhibition of gluconeogenesis and p-aminohipuric acid accumulation in rat renal cortical slices by ionic and nonionic contrast media. | Clinical and experimental nephrology 20030601 |
Assessment of experimentally induced acute changes of renal haemodynamics. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20030501 |
Impairment of the renal p-aminohippurate transport induced by 6-hydroxydopamine. | The Journal of pharmacy and pharmacology 20030501 |
Organic anion transporter 3 (Slc22a8) is a dicarboxylate exchanger indirectly coupled to the Na+ gradient. | American journal of physiology. Renal physiology 20030401 |
Capillary electrophoresis method to measure p-aminohippuric acid in urine and plasma for the assessment of renal plasma flow. | Clinical chemistry 20030401 |
Rat organic anion transporter 3 (rOAT3) is responsible for brain-to-blood efflux of homovanillic acid at the abluminal membrane of brain capillary endothelial cells. | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20030401 |
Increased plasma concentration and brain penetration of methamphetamine in behaviorally sensitized rats. | European journal of pharmacology 20030307 |
Liquid chromatography for iothalamate in biological samples. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030305 |
Glomerular ultrafiltration in normal and preeclamptic pregnancy. | Journal of the American Society of Nephrology : JASN 20030301 |
Impaired tubular excretory function as a late renal side effect of chemotherapy in children. | Journal of pediatric hematology/oncology 20030301 |
Role of BSP/bilirubin binding protein on p-aminohippurate transport in rat kidney. | Molecular and cellular biochemistry 20030301 |
Dendrimers conjugates for colonic delivery of 5-aminosalicylic acid. | Journal of controlled release : official journal of the Controlled Release Society 20030214 |
Effect of feed intake on amino acid transfers across the ovine hindquarters. | The British journal of nutrition 20030201 |
Inhibition of basolateral transport and cellular accumulation of cDDP and N-acetyl- L-cysteine-cDDP by TEA and PAH in the renal proximal tubule. | Cancer chemotherapy and pharmacology 20030201 |
Urate transport via human PAH transporter hOAT1 and its gene structure. | Kidney international 20030101 |
Clearance studies in genetically altered mice. | Methods in molecular medicine 20030101 |
Brain efflux index method. Characterization of efflux transport across the blood-brain barrier. | Methods in molecular medicine 20030101 |
Renal nerves mediate changes in contralateral renal blood flow after extracorporeal shockwave lithotripsy. | Nephron. Physiology 20030101 |
Pitfalls of single-sample determination of renal clearance. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20021201 |
p-Aminohippurate transport at the apical membrane in the OK kidney epithelial cell line. | Pharmaceutical research 20021201 |
The adverse renal effects of prostaglandin-synthesis inhibitors in the newborn rabbit. | Seminars in perinatology 20021201 |
Cloning of the pig renal organic anion transporter 1 (pOAT1). | Biochimie 20021201 |
Interaction of the metal chelator 2,3-dimercapto-1-propanesulfonate with the rabbit multispecific organic anion transporter 1 (rbOAT1). | Molecular pharmacology 20021101 |
Renal functional reserve is well maintained in patients with advanced liver cirrhosis and ascites. | Scandinavian journal of gastroenterology 20021101 |
Urate/alpha-ketoglutarate exchange in avian basolateral membrane vesicles. | American journal of physiology. Cell physiology 20021001 |
Facilitated diffusion of urate in avian brush-border membrane vesicles. | American journal of physiology. Cell physiology 20021001 |
Role of blood-brain barrier organic anion transporter 3 (OAT3) in the efflux of indoxyl sulfate, a uremic toxin: its involvement in neurotransmitter metabolite clearance from the brain. | Journal of neurochemistry 20021001 |
Effects of Juglans sinensis Dode extract and antioxidant on mercury chloride-induced acute renal failure in rabbits. | Journal of ethnopharmacology 20020901 |
Down-regulation of rat organic cation transporter rOCT2 by 5/6 nephrectomy. | Kidney international 20020801 |
Rapid microplate method for PAH estimation. | American journal of physiology. Renal physiology 20020801 |
Short-term regulation of basolateral organic anion uptake in proximal tubular OK cells: EGF acts via MAPK, PLA(2), and COX1. | Journal of the American Society of Nephrology : JASN 20020801 |
Renal organic anion transport system: a mechanism for the basolateral uptake of mercury-thiol conjugates along the pars recta of the proximal tubule. | Toxicology and applied pharmacology 20020801 |
Impaired organic anion transport in kidney and choroid plexus of organic anion transporter 3 (Oat3 (Slc22a8)) knockout mice. | The Journal of biological chemistry 20020726 |
Role of aromatic transmembrane residues of the organic anion transporter, rOAT3, in substrate recognition. | Biochemistry 20020716 |
Expression and function of sodium transporters in two opossum kidney cell clonal sublines. | American journal of physiology. Renal physiology 20020701 |
Evaluation of renal function in transplant patients on tacrolimus therapy. | Journal of clinical pharmacology 20020701 |
Renal interstitial fibrosis (RIF): II. Ultrasound follow up study of single uranyl nitrate administration causing renal dysfunction in rats--comparison with histologic and functional renal parameters. | Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20020701 |
Confocal imaging of organic anion transport in intact rat choroid plexus. | American journal of physiology. Renal physiology 20020501 |
Expression and functional characterization of rat organic anion transporter 3 (rOat3) in the choroid plexus. | Molecular pharmacology 20020501 |
Major role of organic anion transporter 3 in the transport of indoxyl sulfate in the kidney. | Kidney international 20020501 |
Renal hemodynamic effects of somatostatin are not related to inhibition of endogenous insulin release. | Kidney international 20020501 |
Fenoldopam mesylate blocks reductions in renal plasma flow after radiocontrast dye infusion: a pilot trial in the prevention of contrast nephropathy. | American heart journal 20020501 |
Increased renal expression of bilirubin glucuronide transporters in a rat model of obstructive jaundice. | American journal of physiology. Gastrointestinal and liver physiology 20020401 |
Endothelin ETA receptor-subtype specific antagonism does not mitigate the acute systemic or renal effects of exogenous angiotensin II in humans. | European journal of clinical investigation 20020401 |
Sex differences in p-aminohippuric acid transport in rat kidney: role of membrane fluidity and expression of OAT1. | Molecular and cellular biochemistry 20020401 |
Functional involvement of rat organic anion transporter 3 (rOat3; Slc22a8) in the renal uptake of organic anions. | The Journal of pharmacology and experimental therapeutics 20020301 |
Acute and long-term effects of ACE inhibition on renal haemodynamics in glomerular and interstitial nephropathies. | Journal of the renin-angiotensin-aldosterone system : JRAAS 20020301 |
Effects of gender on the pharmacokinetics of drugs secreted by the renal organic anions transport systems in the rat. | Pharmacological research 20020201 |
The distribution of the anti-HIV drug, 2'3'-dideoxycytidine (ddC), across the blood-brain and blood-cerebrospinal fluid barriers and the influence of organic anion transport inhibitors. | Journal of neurochemistry 20020201 |
The anti-influenza drug oseltamivir exhibits low potential to induce pharmacokinetic drug interactions via renal secretion-correlation of in vivo and in vitro studies. | Drug metabolism and disposition: the biological fate of chemicals 20020101 |
Uraemic toxins induce proximal tubular injury via organic anion transporter 1-mediated uptake. | British journal of pharmacology 20020101 |
Comparison of bidirectional cephalexin transport across MDCK and caco-2 cell monolayers: interactions with peptide transporters. | Pharmaceutical research 20020101 |
Molecular characterization of the renal organic anion transporter 1. | Cell biochemistry and biophysics 20020101 |
Isolated lung chemotherapeutic infusions for treatment of pulmonary metastases: a pilot study. | Journal of biomedical science 20020101 |
[The value and adaptability of glomerular filtration rate and reserve test (review of the literature)]. | Medicina (Kaunas, Lithuania) 20020101 |
Transport of anionic drugs across the basolateral membrane of proximal S2 segments of the rabbit kidney. Inverse relationship between the affinity to the p-aminohippurate transport system and the transport rate. | Arzneimittel-Forschung 20020101 |
Alternative high-performance liquid chromatographic assay for p-aminohippuric acid (PAH): effect of aging on PAH excretion in the isolated perfused rat kidney. | Journal of pharmaceutical and biomedical analysis 20011201 |
Effect of angiotensin-converting enzyme inhibitor on renal function in ovarian hyperstimulation syndrome in the rabbit. | Fertility and sterility 20011201 |
Interaction of 2,3-dimercapto-1-propane sulfonate with the human organic anion transporter hOAT1. | The Journal of pharmacology and experimental therapeutics 20011101 |
Mercapturic acids (N-acetylcysteine S-conjugates) as endogenous substrates for the renal organic anion transporter-1. | Molecular pharmacology 20011101 |
Tubular segment-specific biomarkers of nephrotoxicity in the rat. | Toxicology letters 20011015 |
Cationic amino acids involved in dicarboxylate binding of the flounder renal organic anion transporter. | Journal of the American Society of Nephrology : JASN 20011001 |
Renal hemodynamic effect of tacrolimus in renal transplanted children. | Pediatric nephrology (Berlin, Germany) 20011001 |
Impairment of renal vasodilation with l-arginine is related to more severe disease in untreated hypertensive patients. | Hypertension (Dallas, Tex. : 1979) 20011001 |
Adenine nucleotide and calpain inhibitor I protect against atractyloside-induced toxicity in rat renal cortical slices in vitro. | Archives of toxicology 20011001 |
Mild to severe lithium-induced nephropathy models and urine N-acetyl-beta-D-glucosaminidase in rats. | Methods and findings in experimental and clinical pharmacology 20011001 |
Effect of steviol on para-aminohippurate transport by isolated perfused rabbit renal proximal tubule. | The Journal of pharmacology and experimental therapeutics 20010901 |
Hypertension after neonatal uninephrectomy in rats precedes glomerular damage. | Hypertension (Dallas, Tex. : 1979) 20010901 |
Characterization of the mechanisms involved in the gender differences in p-aminohippurate renal elimination in rats. | Canadian journal of physiology and pharmacology 20010901 |
Effects of different nickel compounds on the transport of para-aminohippurate ion by rat renal cortical slices. | Toxicology letters 20010706 |
High-throughput multi-analyte screening for renal disease using capillary electrophoresis. | Journal of pharmaceutical and biomedical analysis 20010701 |
Characterization of the efflux transport of 17beta-estradiol-D-17beta-glucuronide from the brain across the blood-brain barrier. | The Journal of pharmacology and experimental therapeutics 20010701 |
Salviae radix extract prevents cisplatin-induced acute renal failure in rabbits. | Nephron 20010701 |
Molecular physiology of renal p-aminohippurate secretion. | News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society 20010601 |
Arginine 454 and lysine 370 are essential for the anion specificity of the organic anion transporter, rOAT3. | Biochemistry 20010508 |
Isolation of a family of organic anion transporters from human liver and kidney. | Biochemical and biophysical research communications 20010504 |
Sodium retention in preascitic stage of cirrhosis. | Seminars in nephrology 20010501 |
Transport of levofloxacin in the OK kidney epithelial cell line: interaction with p-aminohippurate transport. | Pharmaceutical research 20010501 |
Uptake mechanism of valproic acid in human placental choriocarcinoma cell line (BeWo). | European journal of pharmacology 20010413 |
Effect of oral contraceptives on the renin angiotensin system and renal function. | American journal of physiology. Regulatory, integrative and comparative physiology 20010301 |
Simultaneous determination of inulin and p-aminohippuric acid in plasma and urine by reversed-phase high-performance liquid chromatography. | Journal of chromatography. B, Biomedical sciences and applications 20010210 |
Progress in understanding human ischemic acute renal failure. | American journal of kidney diseases : the official journal of the National Kidney Foundation 20010201 |
Characterization of tubular functional capacity in humans using para-aminohippurate and famotidine. | Kidney international 20010101 |
Organic anion transport across the choroid plexus. | Microscopy research and technique 20010101 |
Secretory transport of p-aminohippuric acid across intestinal epithelial cells in Caco-2 cells and isolated intestinal tissue. | The Journal of pharmacy and pharmacology 20010101 |
Renal function, sodium and water homeostasis in patients with idiopathic extrahepatic portal vein thrombosis compared with normal healthy controls. | South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 20010101 |
Modulation by cyclic AMP and phorbol myristate acetate of cephaloridine-induced injury in rat renal cortical slices. | Japanese journal of pharmacology 20010101 |
The hippurate ratio as an indicator of functional hepatic reserve for resection of hepatocellular carcinoma in cirrhotic patients. | Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20010101 |
Pathophysiology of cyclosporine-induced nephrotoxicity in humans: a role for nitric oxide? | Kidney & blood pressure research 20010101 |
Oxidative stress and renal dysfunction in salt-sensitive hypertension. | Kidney & blood pressure research 20010101 |
Historical control data on urinary and renal tissue biomarkers in naive male Wistar rats. | Journal of applied toxicology : JAT 20010101 |
Metabolism-based polycyclic aromatic acetylene inhibition of CYP1B1 in 10T1/2 cells potentiates aryl hydrocarbon receptor activity. | Toxicology and applied pharmacology 19991201 |
Role of organic anion transporter 1 (OAT1) in cephaloridine (CER)-induced nephrotoxicity. | Kidney international 19991201 |
Renal dysfunction associated with the perioperative use of diclofenac. | Anesthesia and analgesia 19991001 |
Transport of ochratoxin A by renal multispecific organic anion transporter 1. | The Journal of pharmacology and experimental therapeutics 19990601 |
Molecular cloning and characterization of a new multispecific organic anion transporter from rat brain. | The Journal of biological chemistry 19990507 |
Effects of the angiotensin II antagonist valsartan on blood pressure, proteinuria, and renal hemodynamics in patients with chronic renal failure and hypertension. | Journal of the American Society of Nephrology : JASN 19981201 |
Assessment of the role of glutathione conjugation in the protection afforded by anethol dithiolthione against hexachloro-1,3-butadiene-induced nephrotoxicity. | Toxicology and applied pharmacology 19960701 |
Evaluation of the single-injection plasma disappearance of technetium-99m mercaptoacetyltriglycine method for determination of effective renal plasma flow in dogs with normal or abnormal renal function. | American journal of veterinary research 19941201 |
Glutathione status, lipid peroxidation and kidney function in streptozotocin diabetic rats. | Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 19940701 |
Co-expression of human CYP1A1 and a human analog of cytochrome P450-EF in response to 2,3,7,8-tetrachloro-dibenzo-p-dioxin in the human mammary carcinoma-derived MCF-7 cells. | Carcinogenesis 19940401 |
The nephrotoxicity, cytotoxicity and renal handling of a cisplatin-methionine complex in male Wistar rats. | Toxicology 19940325 |
Susceptibility of ageing kidney to quinidine. | Pharmacological research 19940101 |
Caffeine attenuates the renal vascular response to angiotensin II infusion. | Hypertension (Dallas, Tex. : 1979) 19931201 |
Effects of diltiazem on netilmicin-induced nephrotoxicity in rabbits. | Antimicrobial agents and chemotherapy 19930901 |
Acute hepatic and renal toxicity of dichlorobenzene isomers in Fischer 344 rats. | Journal of applied toxicology : JAT 19930101 |
Intrinsic susceptibility of the kidney to acetaminophen toxicity in middle-aged rats. | Toxicology letters 19900601 |
Effects of acute and chronic acyclovir on canine renal function. | The Journal of pharmacology and experimental therapeutics 19890501 |
Effect of alkylxanthines on gentamicin-induced acute renal failure in the rat. | The Journal of pharmacy and pharmacology 19881201 |
Nephrotoxicity of butylated hydroxytoluene in phenobarbital-pretreated male rats. | Archives of toxicology 19880401 |
[Acute reversible kidney insufficiency due to enalapril during diuretic-treated heart insufficiency]. | Deutsche medizinische Wochenschrift (1946) 19870612 |
Urinary tract effects of phensuximide in the Sprague-Dawley and Fischer 344 rat. | Journal of applied toxicology : JAT 19861001 |
Structure/activity studies of the nephrotoxic and mutagenic action of cysteine conjugates of chloro- and fluoroalkenes. | Chemico-biological interactions 19850601 |
Gentamicin nephrotoxicity. I. Degree and permanence of acquired insensitivity. | The Journal of laboratory and clinical medicine 19821001 |
Aspirin-induced depression of glomerular filtration rate in normal humans: role of sodium balance. | Annals of internal medicine 19810301 |
Corticoid effects on angiotensin- and norepinephrine-induced proteinuria in rats. | The American journal of physiology 19790801 |
Nephrotoxic and hepatotoxic effects of triclosan and chlorhexidine in rats. | Toxicology and applied pharmacology 19771001 |