Home Other Building Blocks Aminohippurate sodium

Aminohippurate sodium

CAS No.:
94-16-6
Catalog Number:
AG003UB9
Molecular Formula:
C9H9N2NaO3
Molecular Weight:
216.1691
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
100mg
99%
1 week
United States
$157
- +
Product Description
Catalog Number:
AG003UB9
Chemical Name:
Aminohippurate sodium
CAS Number:
94-16-6
Molecular Formula:
C9H9N2NaO3
Molecular Weight:
216.1691
MDL Number:
MFCD00150723
IUPAC Name:
sodium;2-[(4-aminobenzoyl)amino]acetate
InChI:
InChI=1S/C9H10N2O3.Na/c10-7-3-1-6(2-4-7)9(14)11-5-8(12)13;/h1-4H,5,10H2,(H,11,14)(H,12,13);/q;+1/p-1
InChI Key:
UNZMYCAEMNVPHX-UHFFFAOYSA-M
SMILES:
NC(C(=O)[O-])NC(=O)c1ccccc1.[Na+]
EC Number:
202-309-8
UNII:
SUO3KVS1O9
Properties
Complexity:
227  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
216.051g/mol
Formal Charge:
0
Heavy Atom Count:
15  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
216.172g/mol
Monoisotopic Mass:
216.051g/mol
Rotatable Bond Count:
3  
Topological Polar Surface Area:
95.2A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Literature
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p-Aminohippurate transport at the apical membrane in the OK kidney epithelial cell line. Pharmaceutical research 20021201
The adverse renal effects of prostaglandin-synthesis inhibitors in the newborn rabbit. Seminars in perinatology 20021201
Cloning of the pig renal organic anion transporter 1 (pOAT1). Biochimie 20021201
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Renal functional reserve is well maintained in patients with advanced liver cirrhosis and ascites. Scandinavian journal of gastroenterology 20021101
Urate/alpha-ketoglutarate exchange in avian basolateral membrane vesicles. American journal of physiology. Cell physiology 20021001
Facilitated diffusion of urate in avian brush-border membrane vesicles. American journal of physiology. Cell physiology 20021001
Role of blood-brain barrier organic anion transporter 3 (OAT3) in the efflux of indoxyl sulfate, a uremic toxin: its involvement in neurotransmitter metabolite clearance from the brain. Journal of neurochemistry 20021001
Effects of Juglans sinensis Dode extract and antioxidant on mercury chloride-induced acute renal failure in rabbits. Journal of ethnopharmacology 20020901
Down-regulation of rat organic cation transporter rOCT2 by 5/6 nephrectomy. Kidney international 20020801
Rapid microplate method for PAH estimation. American journal of physiology. Renal physiology 20020801
Short-term regulation of basolateral organic anion uptake in proximal tubular OK cells: EGF acts via MAPK, PLA(2), and COX1. Journal of the American Society of Nephrology : JASN 20020801
Renal organic anion transport system: a mechanism for the basolateral uptake of mercury-thiol conjugates along the pars recta of the proximal tubule. Toxicology and applied pharmacology 20020801
Impaired organic anion transport in kidney and choroid plexus of organic anion transporter 3 (Oat3 (Slc22a8)) knockout mice. The Journal of biological chemistry 20020726
Role of aromatic transmembrane residues of the organic anion transporter, rOAT3, in substrate recognition. Biochemistry 20020716
Expression and function of sodium transporters in two opossum kidney cell clonal sublines. American journal of physiology. Renal physiology 20020701
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Endothelin ETA receptor-subtype specific antagonism does not mitigate the acute systemic or renal effects of exogenous angiotensin II in humans. European journal of clinical investigation 20020401
Sex differences in p-aminohippuric acid transport in rat kidney: role of membrane fluidity and expression of OAT1. Molecular and cellular biochemistry 20020401
Functional involvement of rat organic anion transporter 3 (rOat3; Slc22a8) in the renal uptake of organic anions. The Journal of pharmacology and experimental therapeutics 20020301
Acute and long-term effects of ACE inhibition on renal haemodynamics in glomerular and interstitial nephropathies. Journal of the renin-angiotensin-aldosterone system : JRAAS 20020301
Effects of gender on the pharmacokinetics of drugs secreted by the renal organic anions transport systems in the rat. Pharmacological research 20020201
The distribution of the anti-HIV drug, 2'3'-dideoxycytidine (ddC), across the blood-brain and blood-cerebrospinal fluid barriers and the influence of organic anion transport inhibitors. Journal of neurochemistry 20020201
The anti-influenza drug oseltamivir exhibits low potential to induce pharmacokinetic drug interactions via renal secretion-correlation of in vivo and in vitro studies. Drug metabolism and disposition: the biological fate of chemicals 20020101
Uraemic toxins induce proximal tubular injury via organic anion transporter 1-mediated uptake. British journal of pharmacology 20020101
Comparison of bidirectional cephalexin transport across MDCK and caco-2 cell monolayers: interactions with peptide transporters. Pharmaceutical research 20020101
Molecular characterization of the renal organic anion transporter 1. Cell biochemistry and biophysics 20020101
Isolated lung chemotherapeutic infusions for treatment of pulmonary metastases: a pilot study. Journal of biomedical science 20020101
[The value and adaptability of glomerular filtration rate and reserve test (review of the literature)]. Medicina (Kaunas, Lithuania) 20020101
Transport of anionic drugs across the basolateral membrane of proximal S2 segments of the rabbit kidney. Inverse relationship between the affinity to the p-aminohippurate transport system and the transport rate. Arzneimittel-Forschung 20020101
Alternative high-performance liquid chromatographic assay for p-aminohippuric acid (PAH): effect of aging on PAH excretion in the isolated perfused rat kidney. Journal of pharmaceutical and biomedical analysis 20011201
Effect of angiotensin-converting enzyme inhibitor on renal function in ovarian hyperstimulation syndrome in the rabbit. Fertility and sterility 20011201
Interaction of 2,3-dimercapto-1-propane sulfonate with the human organic anion transporter hOAT1. The Journal of pharmacology and experimental therapeutics 20011101
Mercapturic acids (N-acetylcysteine S-conjugates) as endogenous substrates for the renal organic anion transporter-1. Molecular pharmacology 20011101
Tubular segment-specific biomarkers of nephrotoxicity in the rat. Toxicology letters 20011015
Cationic amino acids involved in dicarboxylate binding of the flounder renal organic anion transporter. Journal of the American Society of Nephrology : JASN 20011001
Renal hemodynamic effect of tacrolimus in renal transplanted children. Pediatric nephrology (Berlin, Germany) 20011001
Impairment of renal vasodilation with l-arginine is related to more severe disease in untreated hypertensive patients. Hypertension (Dallas, Tex. : 1979) 20011001
Adenine nucleotide and calpain inhibitor I protect against atractyloside-induced toxicity in rat renal cortical slices in vitro. Archives of toxicology 20011001
Mild to severe lithium-induced nephropathy models and urine N-acetyl-beta-D-glucosaminidase in rats. Methods and findings in experimental and clinical pharmacology 20011001
Effect of steviol on para-aminohippurate transport by isolated perfused rabbit renal proximal tubule. The Journal of pharmacology and experimental therapeutics 20010901
Hypertension after neonatal uninephrectomy in rats precedes glomerular damage. Hypertension (Dallas, Tex. : 1979) 20010901
Characterization of the mechanisms involved in the gender differences in p-aminohippurate renal elimination in rats. Canadian journal of physiology and pharmacology 20010901
Effects of different nickel compounds on the transport of para-aminohippurate ion by rat renal cortical slices. Toxicology letters 20010706
High-throughput multi-analyte screening for renal disease using capillary electrophoresis. Journal of pharmaceutical and biomedical analysis 20010701
Characterization of the efflux transport of 17beta-estradiol-D-17beta-glucuronide from the brain across the blood-brain barrier. The Journal of pharmacology and experimental therapeutics 20010701
Salviae radix extract prevents cisplatin-induced acute renal failure in rabbits. Nephron 20010701
Molecular physiology of renal p-aminohippurate secretion. News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society 20010601
Arginine 454 and lysine 370 are essential for the anion specificity of the organic anion transporter, rOAT3. Biochemistry 20010508
Isolation of a family of organic anion transporters from human liver and kidney. Biochemical and biophysical research communications 20010504
Sodium retention in preascitic stage of cirrhosis. Seminars in nephrology 20010501
Transport of levofloxacin in the OK kidney epithelial cell line: interaction with p-aminohippurate transport. Pharmaceutical research 20010501
Uptake mechanism of valproic acid in human placental choriocarcinoma cell line (BeWo). European journal of pharmacology 20010413
Effect of oral contraceptives on the renin angiotensin system and renal function. American journal of physiology. Regulatory, integrative and comparative physiology 20010301
Simultaneous determination of inulin and p-aminohippuric acid in plasma and urine by reversed-phase high-performance liquid chromatography. Journal of chromatography. B, Biomedical sciences and applications 20010210
Progress in understanding human ischemic acute renal failure. American journal of kidney diseases : the official journal of the National Kidney Foundation 20010201
Characterization of tubular functional capacity in humans using para-aminohippurate and famotidine. Kidney international 20010101
Organic anion transport across the choroid plexus. Microscopy research and technique 20010101
Secretory transport of p-aminohippuric acid across intestinal epithelial cells in Caco-2 cells and isolated intestinal tissue. The Journal of pharmacy and pharmacology 20010101
Renal function, sodium and water homeostasis in patients with idiopathic extrahepatic portal vein thrombosis compared with normal healthy controls. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 20010101
Modulation by cyclic AMP and phorbol myristate acetate of cephaloridine-induced injury in rat renal cortical slices. Japanese journal of pharmacology 20010101
The hippurate ratio as an indicator of functional hepatic reserve for resection of hepatocellular carcinoma in cirrhotic patients. Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20010101
Pathophysiology of cyclosporine-induced nephrotoxicity in humans: a role for nitric oxide? Kidney & blood pressure research 20010101
Oxidative stress and renal dysfunction in salt-sensitive hypertension. Kidney & blood pressure research 20010101
Historical control data on urinary and renal tissue biomarkers in naive male Wistar rats. Journal of applied toxicology : JAT 20010101
Metabolism-based polycyclic aromatic acetylene inhibition of CYP1B1 in 10T1/2 cells potentiates aryl hydrocarbon receptor activity. Toxicology and applied pharmacology 19991201
Role of organic anion transporter 1 (OAT1) in cephaloridine (CER)-induced nephrotoxicity. Kidney international 19991201
Renal dysfunction associated with the perioperative use of diclofenac. Anesthesia and analgesia 19991001
Transport of ochratoxin A by renal multispecific organic anion transporter 1. The Journal of pharmacology and experimental therapeutics 19990601
Molecular cloning and characterization of a new multispecific organic anion transporter from rat brain. The Journal of biological chemistry 19990507
Effects of the angiotensin II antagonist valsartan on blood pressure, proteinuria, and renal hemodynamics in patients with chronic renal failure and hypertension. Journal of the American Society of Nephrology : JASN 19981201
Assessment of the role of glutathione conjugation in the protection afforded by anethol dithiolthione against hexachloro-1,3-butadiene-induced nephrotoxicity. Toxicology and applied pharmacology 19960701
Evaluation of the single-injection plasma disappearance of technetium-99m mercaptoacetyltriglycine method for determination of effective renal plasma flow in dogs with normal or abnormal renal function. American journal of veterinary research 19941201
Glutathione status, lipid peroxidation and kidney function in streptozotocin diabetic rats. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 19940701
Co-expression of human CYP1A1 and a human analog of cytochrome P450-EF in response to 2,3,7,8-tetrachloro-dibenzo-p-dioxin in the human mammary carcinoma-derived MCF-7 cells. Carcinogenesis 19940401
The nephrotoxicity, cytotoxicity and renal handling of a cisplatin-methionine complex in male Wistar rats. Toxicology 19940325
Susceptibility of ageing kidney to quinidine. Pharmacological research 19940101
Caffeine attenuates the renal vascular response to angiotensin II infusion. Hypertension (Dallas, Tex. : 1979) 19931201
Effects of diltiazem on netilmicin-induced nephrotoxicity in rabbits. Antimicrobial agents and chemotherapy 19930901
Acute hepatic and renal toxicity of dichlorobenzene isomers in Fischer 344 rats. Journal of applied toxicology : JAT 19930101
Intrinsic susceptibility of the kidney to acetaminophen toxicity in middle-aged rats. Toxicology letters 19900601
Effects of acute and chronic acyclovir on canine renal function. The Journal of pharmacology and experimental therapeutics 19890501
Effect of alkylxanthines on gentamicin-induced acute renal failure in the rat. The Journal of pharmacy and pharmacology 19881201
Nephrotoxicity of butylated hydroxytoluene in phenobarbital-pretreated male rats. Archives of toxicology 19880401
[Acute reversible kidney insufficiency due to enalapril during diuretic-treated heart insufficiency]. Deutsche medizinische Wochenschrift (1946) 19870612
Urinary tract effects of phensuximide in the Sprague-Dawley and Fischer 344 rat. Journal of applied toxicology : JAT 19861001
Structure/activity studies of the nephrotoxic and mutagenic action of cysteine conjugates of chloro- and fluoroalkenes. Chemico-biological interactions 19850601
Gentamicin nephrotoxicity. I. Degree and permanence of acquired insensitivity. The Journal of laboratory and clinical medicine 19821001
Aspirin-induced depression of glomerular filtration rate in normal humans: role of sodium balance. Annals of internal medicine 19810301
Corticoid effects on angiotensin- and norepinephrine-induced proteinuria in rats. The American journal of physiology 19790801
Nephrotoxic and hepatotoxic effects of triclosan and chlorhexidine in rats. Toxicology and applied pharmacology 19771001
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