Home Other Building Blocks Prednisolone phosphate sodium

Prednisolone phosphate sodium

CAS No.:
125-02-0
Catalog Number:
AG003TYD
Molecular Formula:
C21H27Na2O8P
Molecular Weight:
484.3876
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
100mg
98%(HPLC)
In Stock USA
United States
$119
- +
500mg
98%(HPLC)
In Stock USA
United States
$153
- +
1g
98%(HPLC)
In Stock USA
United States
$196
- +
5g
98%(HPLC)
In Stock USA
United States
$487
- +
Product Description
Catalog Number:
AG003TYD
Chemical Name:
Prednisolone phosphate sodium
CAS Number:
125-02-0
Molecular Formula:
C21H27Na2O8P
Molecular Weight:
484.3876
MDL Number:
MFCD00083682
IUPAC Name:
disodium;[2-[(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] phosphate
InChI:
InChI=1S/C21H29O8P.2Na/c1-19-7-5-13(22)9-12(19)3-4-14-15-6-8-21(25,17(24)11-29-30(26,27)28)20(15,2)10-16(23)18(14)19;;/h5,7,9,14-16,18,23,25H,3-4,6,8,10-11H2,1-2H3,(H2,26,27,28);;/q;2*+1/p-2/t14-,15-,16-,18+,19-,20-,21-;;/m0../s1
InChI Key:
VJZLQIPZNBPASX-OJJGEMKLSA-L
SMILES:
O=C1C=C[C@]2(C(=C1)CC[C@@H]1[C@@H]2[C@@H](O)C[C@]2([C@H]1CC[C@]2(O)C(=O)COP(=O)([O-])[O-])C)C.[Na+].[Na+]
EC Number:
204-722-9
UNII:
IV021NXA9J
Properties
Complexity:
878  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
3  
Defined Atom Stereocenter Count:
7  
Defined Bond Stereocenter Count:
0
Exact Mass:
484.124g/mol
Formal Charge:
0
Heavy Atom Count:
32  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
484.392g/mol
Monoisotopic Mass:
484.124g/mol
Rotatable Bond Count:
3  
Topological Polar Surface Area:
147A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Literature
Title Journal
Cyclodextrin as membrane protectant in spray-drying and freeze-drying of PEGylated liposomes. International journal of pharmaceutics 20121115
MRI evaluation of the antitumor activity of paramagnetic liposomes loaded with prednisolone phosphate. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20120312
The steroids for corneal ulcers trial: study design and baseline characteristics. Archives of ophthalmology (Chicago, Ill. : 1960) 20120201
Corticosteroids for bacterial keratitis: the Steroids for Corneal Ulcers Trial (SCUT). Archives of ophthalmology (Chicago, Ill. : 1960) 20120201
Pseudomonas aeruginosa keratitis: outcomes and response to corticosteroid treatment. Investigative ophthalmology & visual science 20120101
Liposomal targeting of glucocorticoids to the inflamed synovium inhibits cartilage matrix destruction during murine antigen-induced arthritis. International journal of pharmaceutics 20110920
Safety of glucocorticoids can be improved by lower yet still effective dosages of liposomal steroid formulations in murine antigen-induced arthritis: comparison of prednisolone with budesonide. International journal of pharmaceutics 20110920
Intravenously delivered glucocorticoid liposomes inhibit osteoclast activity and bone erosion in murine antigen-induced arthritis. Journal of controlled release : official journal of the Controlled Release Society 20110630
Multi-parametric assessment of the anti-angiogenic effects of liposomal glucocorticoids. Angiogenesis 20110501
Anti-tumor activity of liposomal glucocorticoids: The relevance of liposome-mediated drug delivery, intratumoral localization and systemic activity. Journal of controlled release : official journal of the Controlled Release Society 20110410
Photographic monitoring of herpes simplex virus keratitis during anti-inflammatory treatment. Archives of ophthalmology (Chicago, Ill. : 1960) 20110201
Interaction between topically and systemically coadministered P-glycoprotein substrates/inhibitors: effect on vitreal kinetics. Drug metabolism and disposition: the biological fate of chemicals 20101001
Immunosuppressive effects in infants treated with corticosteroids for infantile hemangiomas. Archives of dermatology 20100701
The effect of liposome-delivered prednisolone on collagen density, myofibroblasts, and fibrous capsule thickness around silicone breast implants in rats. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 20100101
Steroid-induced intraocular pressure elevation or glaucoma after penetrating keratoplasty in patients with keratoconus or Fuchs dystrophy. Cornea 20090801
Prophylaxis of diffuse lamellar keratitis with intraoperative interface steroids in LASIK. Journal of refractive surgery (Thorofare, N.J. : 1995) 20090301
Corticosteroids for bacterial corneal ulcers. The British journal of ophthalmology 20090201
Liposomal glucocorticoids as tumor-targeted anti-angiogenic nanomedicine in B16 melanoma-bearing mice. The Journal of steroid biochemistry and molecular biology 20080701
Antitumor activity and tumor localization of liposomal glucocorticoids in B16 melanoma-bearing mice. Journal of controlled release : official journal of the Controlled Release Society 20080421
Deep corneal calcification associated with preservative-free eyedrops and persistent epithelial defects. Cornea 20080401
Antitumor activity of liposomal prednisolone phosphate depends on the presence of functional tumor-associated macrophages in tumor tissue. Neoplasia (New York, N.Y.) 20080201
Advances in targeting drug delivery to glomerular mesangial cells by long circulating cationic liposomes for the treatment of glomerulonephritis. Pharmaceutical research 20070501
Prednisolone phosphate-containing TRX-20 liposomes inhibit cytokine and chemokine production in human fibroblast-like synovial cells: a novel approach to rheumatoid arthritis therapy. The Journal of pharmacy and pharmacology 20070101
Anti-angiogenic effects of liposomal prednisolone phosphate on B16 melanoma in mice. Journal of controlled release : official journal of the Controlled Release Society 20060612
[Determination of prednisolone sodium phosphate and the related substances by reversed-phase high performance liquid chromatography]. Se pu = Chinese journal of chromatography 20060101
Administration of prednisolone phosphate-liposomes reduces wound contraction in a rat partial-thickness wound model. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 20060101
Effect of multipurpose solutions for contact lens care on the in vitro drug-induced spoliation of poly(2-hydroxyethyl methacrylate) in simulated aqueous humour. Contact lens & anterior eye : the journal of the British Contact Lens Association 20050301
Liposome-encapsulated prednisolone phosphate inhibits growth of established tumors in mice. Neoplasia (New York, N.Y.) 20050201
Liposomal targeting of glucocorticoids to synovial lining cells strongly increases therapeutic benefit in collagen type II arthritis. Annals of the rheumatic diseases 20040401
Complete remission of experimental arthritis by joint targeting of glucocorticoids with long-circulating liposomes. Arthritis and rheumatism 20030701
Effect of immunosuppression on outcome measures in a model of rat limbal transplantation. Investigative ophthalmology & visual science 20020301
Peripapillary subretinal neovascularization in sarcoidosis: remission and exacerbation during oral corticosteroid therapy. Japanese journal of ophthalmology 20020101
Effect of steroid-liposome on immunohistopathology of IgA nephropathy in ddY mice. Nephron 20011001
[The new experimental ulcerative colitis model in rats induced by subserosal injection of acetic acid]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20010801
Mycobacterium keratitis following hyperopic laser in situ keratomileusis. Canadian journal of ophthalmology. Journal canadien d'ophtalmologie 20010801
Atopic dermatitis: a case report and current clinical review of systemic and ocular manifestations. Optometry (St. Louis, Mo.) 20010201
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