Potassium canrenoate
| Title | Journal |
|---|---|
| Population pharmacokinetic model of canrenone after intravenous administration of potassium canrenoate to paediatric patients. | British journal of clinical pharmacology 20121101 |
| Clinically insignificant negative interferences of spironolactone, potassium canrenoate, and their common metabolite canrenone in new dimension vista LOCI digoxin immunoassay. | Journal of clinical laboratory analysis 20120501 |
| Antigenotoxic effect of the Plumbago zeylanica extract against the genotoxic damage induced by potassium canrenoate in cultured human peripheral blood lymphocytes. | Drug and chemical toxicology 20120401 |
| Mineralocorticoids participate in the reduced vascular reactivity of pregnant rats. | American journal of physiology. Heart and circulatory physiology 20120301 |
| Activation of the mineralocorticoid receptor increases striatin levels. | American journal of hypertension 20120201 |
| Prenatal corticosteroid exposure alters early developmental seizures and behavior. | Epilepsy research 20110601 |
| Differential effects of mineralocorticoid blockade on the hypothalamo-pituitary-adrenal axis in pregnant and nonpregnant ewes. | American journal of physiology. Endocrinology and metabolism 20110301 |
| Abbott ARCHITECT clinical chemistry and immunoassay systems: digoxin assays are free of interferences from spironolactone, potassium canrenoate, and their common metabolite canrenone. | Therapeutic drug monitoring 20110201 |
| Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. | Bioorganic & medicinal chemistry letters 20101101 |
| Rationale for an early aldosterone blockade in acute myocardial infarction and design of the ALBATROSS trial. | American heart journal 20101001 |
| A severe case of warfarin-canrenoate interaction: a role for genetic predisposition? | British journal of haematology 20100801 |
| Cardioprotective effects of mineralocorticoid receptor antagonists at reperfusion. | European heart journal 20100701 |
| Spironolactone and canrenone inhibit UGT2B7-catalyzed human liver and kidney microsomal aldosterone 18beta-glucuronidation: a potential drug interaction. | Drug metabolism and disposition: the biological fate of chemicals 20100701 |
| Effect of acute and prolonged mineralocorticoid receptor blockade on spontaneous and stimulated hypothalamic-pituitary-adrenal axis in humans. | European journal of endocrinology 20100601 |
| Liver: diuretic agents for ascites: joining forces from the start? | Nature reviews. Gastroenterology & hepatology 20100601 |
| Amiloride reduces portal hypertension in rat liver cirrhosis. | Gut 20100601 |
| Steroidogenesis vs. steroid uptake in the heart: do corticosteroids mediate effects via cardiac mineralocorticoid receptors? | Journal of hypertension 20100501 |
| Combined versus sequential diuretic treatment of ascites in non-azotaemic patients with cirrhosis: results of an open randomised clinical trial. | Gut 20100101 |
| Effect of spironolactone, potassium canrenoate, and their common metabolite canrenone on Dimension Vista Digoxin Assay. | Journal of clinical laboratory analysis 20100101 |
| Effect of spironolactone, potassium canrenoate and their common metabolite canrenone on serum digoxin measurement by digoxin III, a new digoxin immunoassay. | Therapeutic drug monitoring 20081201 |
| Menopause not aldosterone-to-renin ratio predicts blood pressure response to a mineralocorticoid receptor antagonist in primary care hypertensive patients. | American journal of hypertension 20080901 |
| Cardiac corticosteroid receptors mediate the enlargement of the ovine fetal heart induced by chronic increases in maternal cortisol. | The Journal of endocrinology 20080801 |
| Corticosteroids mediate fast feedback of the rat hypothalamic-pituitary-adrenal axis via the mineralocorticoid receptor. | American journal of physiology. Endocrinology and metabolism 20080601 |
| Time-course reduction of renal function in rats on high sodium intake: acute reversal by potassium canrenoate. | Clinical and experimental pharmacology & physiology 20080401 |
| Fadrozole reverses cardiac fibrosis in spontaneously hypertensive heart failure rats: discordant enantioselectivity versus reduction of plasma aldosterone. | Endocrinology 20080101 |
| Spontaneous resolution of idiopathic aldosteronism after long-term treatment with potassium canrenoate. | Hypertension (Dallas, Tex. : 1979) 20071001 |
| Mineralocorticoid receptor antagonists. | Current hypertension reports 20070301 |
| Renal sodium retention in cirrhotic rats depends on glucocorticoid-mediated activation of mineralocorticoid receptor due to decreased renal 11beta-HSD-2 activity. | American journal of physiology. Regulatory, integrative and comparative physiology 20070101 |
| Primary hyperaldosteronism is associated with derangement in the regulation of the hypothalamus-pituitary-adrenal axis in humans. | Journal of endocrinological investigation 20070101 |
| Effect of potassium canrenoate, an anti-aldosterone agent, on incidence of ascites and variceal progression in cirrhosis. | Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20061101 |
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 |
| Effects of canrenoate plus angiotensin-converting enzyme inhibitors versus angiotensin-converting enzyme inhibitors alone on systolic and diastolic function in patients with acute anterior myocardial infarction. | American heart journal 20051101 |
| Hypothalamus-pituitary-adrenal hyperactivity in human aging is partially refractory to stimulation by mineralocorticoid receptor blockade. | The Journal of clinical endocrinology and metabolism 20051001 |
| Spironolactone and its main metabolite canrenoic acid block hKv1.5, Kv4.3 and Kv7.1 + minK channels. | British journal of pharmacology 20050901 |
| Cardiac, neuroadrenergic, and portal hemodynamic effects of prolonged aldosterone blockade in postviral child A cirrhosis. | The American journal of gastroenterology 20050501 |
| Aldosterone blunts human baroreflex sensitivity by a nongenomic mechanism. | Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20050501 |
| Idiopathic primary hyperaldosteronism: normalization of plasma aldosterone after one month withdrawal of long-term therapy with aldosterone-receptor antagonist potassium canrenoate. | Journal of endocrinological investigation 20050301 |
| Inhibition of catecholamine-induced cardiac fibrosis by an aldosterone antagonist. | Journal of cardiovascular pharmacology 20050101 |
| Electropharmacological effects of a spironolactone derivative, potassium canrenoate, assessed in the halothane-anesthetized canine model. | Journal of pharmacological sciences 20041201 |
| Elevated resting and exercise-induced cortisol levels after mineralocorticoid receptor blockade with canrenoate in healthy humans. | The Journal of clinical endocrinology and metabolism 20041001 |
| Effects of the aldosterone receptor antagonist potassium canrenoate on renal blood flow and urinary output during prolonged increased intraabdominal pressure (IAP) in pigs. | Surgical endoscopy 20041001 |
| Potassium canrenoate, an aldosterone receptor antagonist, reduces isoprenaline-induced cardiac fibrosis in the rat. | The Journal of pharmacology and experimental therapeutics 20040601 |
| Acute aldosterone antagonism improves cardiac vagal control in humans. | Journal of the American College of Cardiology 20040407 |
| Spironolactone inhibits production of proinflammatory cytokines by human mononuclear cells. | Immunology letters 20040215 |
| Comparative evaluation of digoxin concentrations determined by three assay systems: TDx, IMx and OPUS. | Biopharmaceutics & drug disposition 20040101 |
| Aldosterone blockade in patients with acute myocardial infarction. | Circulation 20031223 |
| Mineralocorticoid action and sodium-hydrogen exchange: studies in experimental cardiac fibrosis. | Endocrinology 20030901 |
| A new turbidometric digoxin immunoassay on the ADVIA 1650 analyzer is free from interference by spironolactone, potassium canrenoate, and their common metabolite canrenone. | Therapeutic drug monitoring 20030801 |
| Spironolactone and its main metabolite, canrenoic acid, block human ether-a-go-go-related gene channels. | Circulation 20030218 |
| The stimulatory effect of canrenoate, a mineralocorticoid antagonist, on the activity of the hypothalamus-pituitary-adrenal axis is abolished by alprazolam, a benzodiazepine, in humans. | The Journal of clinical endocrinology and metabolism 20021001 |
| DNA damage in tissues of rat treated with potassium canrenoate. | Toxicology 20020227 |
| Bidirectional (positive/negative) interference of spironolactone, canrenone, and potassium canrenoate on serum digoxin measurement: elimination of interference by measuring free digoxin or using a chemiluminescent assay for digoxin. | Journal of clinical laboratory analysis 20020101 |
| Mineralocorticoid receptor blockade by canrenoate increases both spontaneous and stimulated adrenal function in humans. | The Journal of clinical endocrinology and metabolism 20010701 |
| Aldosterone and myocardial infarction--are aldosterone antagonists needed to prevent remodelling or does ACE inhibition suffice? | Cardiovascular drugs and therapy 20010701 |
| ACE-inhibition plus mineralocorticoid antagonism versus ACE-inhibition alone in patients with anterior myocardial infarction. | Cardiovascular drugs and therapy 20010701 |
| Collecting duct is a site of sodium retention in PAN nephrosis: a rationale for amiloride therapy. | Journal of the American Society of Nephrology : JASN 20010301 |
| The combination ace-inhibitors plus canreonate in patients with anterior myocardial infarction: safety and tolerability study. | International journal of cardiology 20010201 |
| Additional beneficial effects of canrenoate in patients with anterior myocardial infarction on ACE-inhibitor treatment. A pilot study. | Italian heart journal : official journal of the Italian Federation of Cardiology 20010201 |
| Aldosterone inhibition limits collagen synthesis and progressive left ventricular enlargement after anterior myocardial infarction. | American heart journal 20010101 |
| [Effect of furosemide, potassium canrenoate and D-L-propranolol on blood pressure in spontaneously hypertensive rat]. | Pathologie-biologie 19760501 |