Pleconaril
| Title | Journal |
|---|---|
| Evaluation of intravenous midazolam limited sampling models to determine area under the concentration time curve during cytochrome P450 3A baseline, inhibition and induction or activation. | International journal of clinical pharmacology and therapeutics 20120701 |
| Alkaloids from the root of Isatis indigotica. | Journal of natural products 20120622 |
| In vitro and in vivo evaluation of ribavirin and pleconaril antiviral activity against enterovirus 71 infection. | Archives of virology 20120401 |
| Daphne Genkwa sieb. Et zucc. Water-soluble extracts act on enterovirus 71 by inhibiting viral entry. | Viruses 20120401 |
| Combating enterovirus replication: state-of-the-art on antiviral research. | Biochemical pharmacology 20120115 |
| Pleconaril revisited: clinical course of chronic enteroviral meningoencephalitis after treatment correlates with in vitro susceptibility. | Antiviral therapy 20120101 |
| Oncolytic virotherapy for hematological malignancies. | Advances in virology 20120101 |
| In-Silico screening of Pleconaril and its novel substituted derivatives with Neuraminidase of H1N1 Influenza strain. | BMC research notes 20120101 |
| Inhibition of enterovirus 71 (EV-71) infections by a novel antiviral peptide derived from EV-71 capsid protein VP1. | PloS one 20120101 |
| Pharmacological and biological antiviral therapeutics for cardiac coxsackievirus infections. | Molecules (Basel, Switzerland) 20111011 |
| Towards the design of combination therapy for the treatment of enterovirus infections. | Antiviral research 20110601 |
| Neonatal myocardial infarction or myocarditis? | Pediatric cardiology 20110401 |
| Pharmacophore-based design, synthesis, and biological evaluation of novel chloro-pyridazine piperazines as human rhinovirus (HRV-3) inhibitors. | Bioorganic & medicinal chemistry letters 20110201 |
| Complete coding sequence characterization and comparative analysis of the putative novel human rhinovirus (HRV) species C and B. | Virology journal 20110101 |
| Curing the common cold. | Scientific American 20110101 |
| Genetic diversity of a Korean echovirus 5 isolate and response of the strain to five antiviral drugs. | Virology journal 20110101 |
| Pleconaril-resistant chronic parechovirus-associated enteropathy in agammaglobulinaemia. | Antiviral therapy 20110101 |
| Antiviral activity of 3(2H)- and 6-chloro-3(2H)-isoflavenes against highly diverged, neurovirulent vaccine-derived, type2 poliovirus sewage isolates. | PloS one 20110101 |
| Cytolytic replication of echoviruses in colon cancer cell lines. | Virology journal 20110101 |
| Oncolytic virotherapy for multiple myeloma: past, present, and future. | Bone marrow research 20110101 |
| Hepatitis and Encephalitis due to Coxsackie Virus A9 in an Adult. | Case reports in gastroenterology 20110101 |
| Assessment of oral midazolam limited sampling strategies to predict area under the concentration time curve (AUC) during cytochrome P450 (CYP) 3A baseline, inhibition and induction or activation. | International journal of clinical pharmacology and therapeutics 20101201 |
| The need for treatment against human parechoviruses: how, why and when? | Expert review of anti-infective therapy 20101201 |
| Clinical features, diagnosis, and management of enterovirus 71. | The Lancet. Neurology 20101101 |
| Viral meningoencephalitis: a review of diagnostic methods and guidelines for management. | European journal of neurology 20100801 |
| Enterovirus genotype EV-104 in humans, Italy, 2008-2009. | Emerging infectious diseases 20100601 |
| Enterovirus 71 infection: An experience in Korea, 2009. | Korean journal of pediatrics 20100501 |
| Anti-human rhinovirus activity of raoulic acid from Raoulia australis. | Journal of medicinal food 20100401 |
| MicroRNA antagonism of the picornaviral life cycle: alternative mechanisms of interference. | PLoS pathogens 20100301 |
| Rhinovirus genome evolution during experimental human infection. | PloS one 20100101 |
| An RNA replication-center assay for high content image-based quantifications of human rhinovirus and coxsackievirus infections. | Virology journal 20100101 |
| Human rhinovirus C: a newly discovered human rhinovirus species. | Emerging health threats journal 20100101 |
| Antiviral treatments reduce severity of diabetes in Ljungan virus-infected CD-1 mice and delay onset in diabetes-prone BB rats. | Microbiology and immunology 20091001 |
| Role of rhinovirus C in apparently life-threatening events in infants, Spain. | Emerging infectious diseases 20090901 |
| New perspectives of infections in cardiovascular disease. | Current cardiology reviews 20090501 |
| New pleconaril and [(biphenyloxy)propyl]isoxazole derivatives with substitutions in the central ring exhibit antiviral activity against pleconaril-resistant coxsackievirus B3. | Antiviral research 20090101 |
| Frequency and clinical relevance of human bocavirus infection in acute exacerbations of chronic obstructive pulmonary disease. | International journal of chronic obstructive pulmonary disease 20090101 |
| Limited duration of vaccine poliovirus and other enterovirus excretion among human immunodeficiency virus infected children in Kenya. | BMC infectious diseases 20090101 |
| Selective inhibitors of picornavirus replication. | Medicinal research reviews 20081101 |
| Novel human rhinoviruses and exacerbation of asthma in children. | Emerging infectious diseases 20081101 |
| Potential use of antiviral agents in polio eradication. | Emerging infectious diseases 20080401 |
| Treatment of viral myocarditis caused by coxsackievirus B. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20080115 |
| Enterovirus-associated hemophagocytic syndrome in children with malignancy: report of three cases and review of the literature. | European journal of pediatrics 20080101 |
| Distinguishing molecular features and clinical characteristics of a putative new rhinovirus species, human rhinovirus C (HRV C). | PloS one 20080101 |
| Iota-Carrageenan is a potent inhibitor of rhinovirus infection. | Virology journal 20080101 |
| A case report of a premature infant with coxsackie B1 meningitis. | Advances in neonatal care : official journal of the National Association of Neonatal Nurses 20071001 |
| Quantitative structure-activity relationship studies of [(biphenyloxy)propyl]isoxazole derivatives. Inhibitors of human rhinovirus 2 replication. | Journal of medicinal chemistry 20070823 |
| WITHDRAWN: Antivirals for the common cold. | The Cochrane database of systematic reviews 20070718 |
| Fatal coxsackievirus A-16 pneumonitis in adult. | Emerging infectious diseases 20070701 |
| Characterisation of a newly identified human rhinovirus, HRV-QPM, discovered in infants with bronchiolitis. | Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 20070601 |
| Sufficiently important difference for common cold: severity reduction. | Annals of family medicine 20070501 |
| Enteroviral infections in children with malignant disease: a 5-year study in a single institution. | The Journal of infection 20070401 |
| Antiviral treatment of Coxsackie B virus infection in human pancreatic islets. | Antiviral research 20070401 |
| Genome-wide diversity and selective pressure in the human rhinovirus. | Virology journal 20070101 |
| Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20061201 |
| Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20060601 |
| Duration of pleconaril effect on cytochrome P450 3A activity in healthy adults using the oral biomarker midazolam. | Drug metabolism and disposition: the biological fate of chemicals 20060501 |
| Investigation of treatment failure in neonatal echovirus 7 infection. | The Pediatric infectious disease journal 20060301 |
| The effect of oral pleconaril on hepatic cytochrome P450 3A activity in healthy adults using intravenous midazolam as a probe. | Journal of clinical pharmacology 20060101 |
| Current status of anti-picornavirus therapies. | Current pharmaceutical design 20060101 |
| An experimental model of rhinovirus induced chronic obstructive pulmonary disease exacerbations: a pilot study. | Respiratory research 20060101 |
| Insights into the genetic basis for natural phenotypic resistance of human rhinoviruses to pleconaril. | Antiviral research 20051201 |
| Pharmacophore modeling, docking, and principal component analysis based clustering: combined computer-assisted approaches to identify new inhibitors of the human rhinovirus coat protein. | Journal of medicinal chemistry 20051006 |
| Susceptibility of coxsackievirus B3 laboratory strains and clinical isolates to the capsid function inhibitor pleconaril: antiviral studies with virus chimeras demonstrate the crucial role of amino acid 1092 in treatment. | The Journal of antimicrobial chemotherapy 20051001 |
| Pharmacokinetics of antivirals in neonate. | Early human development 20050901 |
| Coxsackievirus-induced myocarditis: new trends in treatment. | Expert review of anti-infective therapy 20050801 |
| Viral encephalitis: a review of diagnostic methods and guidelines for management. | European journal of neurology 20050501 |
| 2-Ethoxybenzoxazole as a bioisosteric replacement of an ethyl benzoate group in a human rhinovirus (HRV) capsid binder. | Bioorganic & medicinal chemistry letters 20050415 |
| Pleconaril--an advance in the treatment of enteroviral infection in immuno-compromised patients. | Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 20050101 |
| Using benefit harm tradeoffs to estimate sufficiently important difference: the case of the common cold. | Medical decision making : an international journal of the Society for Medical Decision Making 20050101 |
| [Rhinovirus diseases: pathogenesis, diagnostics and treatment]. | Zhurnal mikrobiologii, epidemiologii, i immunobiologii 20050101 |
| Failure to clear persistent vaccine-derived neurovirulent poliovirus infection in an immunodeficient man. | Lancet (London, England) 20040508 |
| Neonatal coxsackie B virus infection-a treatable disease? | European journal of pediatrics 20040401 |
| Presentation, diagnosis, and management of enterovirus infections in neonates. | Paediatric drugs 20040101 |
| Safety and efficacy evaluation of pleconaril for treatment of the common cold. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20031215 |
| Pleconaril for infantile enterovirus meningitis. | Current neurology and neuroscience reports 20031101 |
| Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. 8. Pharmacological optimization of orally bioavailable 2-pyridone-containing peptidomimetics. | Journal of medicinal chemistry 20031009 |
| Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20031001 |
| Human rhinovirus capsid dynamics is controlled by canyon flexibility. | Virology 20030915 |
| An orally bioavailable oxime ether capsid binder with potent activity against human rhinovirus. | Journal of medicinal chemistry 20030717 |
| Neurogenic pulmonary edema in enterovirus 71 encephalitis is not uniformly fatal but causes severe morbidity in survivors. | Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 20030701 |
| Antiviral activity of betulin, betulinic and betulonic acids against some enveloped and non-enveloped viruses. | Fitoterapia 20030701 |
| Efficacy and safety of oral pleconaril for treatment of colds due to picornaviruses in adults: results of 2 double-blind, randomized, placebo-controlled trials. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20030615 |
| Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20030601 |
| Survival after pulmonary edema due to enterovirus 71 encephalitis. | Neurology 20030527 |
| Nucleotide variation in Sabin type 2 poliovirus from an immunodeficient patient with poliomyelitis. | The Journal of general virology 20030501 |
| Diagnosis and treatment of rhinovirus respiratory infections. | Chest 20030501 |
| Double blind placebo-controlled trial of pleconaril in infants with enterovirus meningitis. | The Pediatric infectious disease journal 20030401 |
| Pleconaril, a novel antipicornaviral agent. | Pharmacotherapy 20030301 |
| SPECT scans for monitoring response to pleconaril therapy in chronic enteroviral meningoencephalitis. | The Journal of infection 20030201 |
| Enteroviral infections in primary immunodeficiency (PID): a survey of morbidity and mortality. | The Journal of infection 20030101 |
| A fatal case of coxsackievirus B4 meningoencephalitis. | Archives of neurology 20030101 |
| Viral respiratory infections due to rhinoviruses: current knowledge, new developments. | American journal of therapeutics 20030101 |
| [Polio-like myelitis due to Coxsackie-Virus B 3: Course under treatment with pleconaril]. | Klinische Padiatrie 20030101 |
| Severe Coxsackie virus B infection in preterm newborns treated with pleconaril. | European journal of pediatrics 20020901 |
| Management of viral infections in immunocompromised cancer patients. | Swiss medical weekly 20020713 |
| Cold comfort. | The Lancet. Infectious diseases 20020701 |
| FDA panel rejects common cold treatment. | The Lancet. Infectious diseases 20020501 |
| Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20020501 |
| Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. 6. Structure-activity studies of orally bioavailable, 2-pyridone-containing peptidomimetics. | Journal of medicinal chemistry 20020411 |
| Design, synthesis, and structure-activity relationship of pyridyl imidazolidinones: a novel class of potent and selective human enterovirus 71 inhibitors. | Journal of medicinal chemistry 20020411 |
| Challenges and options in the management of viral infections after stem cell transplantation. | Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20020401 |
| Gateways to Clinical Trials. | Methods and findings in experimental and clinical pharmacology 20020401 |
| Highlights in the development of new antiviral agents. | Mini reviews in medicinal chemistry 20020401 |
| Oral pleconaril treatment of picornavirus-associated viral respiratory illness in adults: efficacy and tolerability in phase II clinical trials. | Antiviral therapy 20020301 |
| Viral encephalitis: familiar infections and emerging pathogens. | Lancet (London, England) 20020209 |
| Enterovirus infections: diagnosis and treatment. | Seminars in pediatric infectious diseases 20020101 |
| Recent advances in the treatment of rhinovirus infections. | Current opinion in pharmacology 20011001 |
| Acute flaccid paralysis syndrome associated with echovirus 19, managed with pleconaril and intravenous immunoglobulin. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20010901 |
| Antiviral agents for influenza, hepatitis C and herpesvirus, enterovirus and rhinovirus infections. | The Medical journal of Australia 20010716 |
| Severe neonatal enteroviral hepatitis treated with pleconaril. | The Pediatric infectious disease journal 20010401 |
| Treatment of ALS with pleconaril. | Neurology 20010313 |
| Enterovirus infections: diagnosis and treatment. | Current opinion in pediatrics 20010201 |
| Pleconaril: a novel antipicornaviral drug. | Expert opinion on investigational drugs 20010201 |
| What's new with enteroviral infections? | Current opinion in pediatrics 20010201 |
| Treatment of potentially life-threatening enterovirus infections with pleconaril. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20010115 |
| Successful treatment of enterovirus infection with the use of pleconaril in 2 infants with severe combined immunodeficiency. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20010101 |
| The treatment of rhinovirus infections: progress and potential. | Antiviral research 20010101 |
| Antivirals for the common cold. | The Cochrane database of systematic reviews 20010101 |
| In vitro activity of pleconaril and AG7088 against selected serotypes and clinical isolates of human rhinoviruses. | Antiviral research 20000901 |
| In vitro antiviral activity of AG7088, a potent inhibitor of human rhinovirus 3C protease. | Antimicrobial agents and chemotherapy 19991001 |
| Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. 4. Incorporation of P1 lactam moieties as L-glutamine replacements. | Journal of medicinal chemistry 19990408 |