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Nialamide

CAS No.:
51-12-7
Catalog Number:
AG003T2N
Molecular Formula:
C16H18N4O2
Molecular Weight:
298.3397
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
100mg
95%
1 week
United States
$140
- +
1g
1 week
United States
$270
- +
5g
1 week
United States
$917
- +
10g
1 week
United States
$1753
- +
Product Description
Catalog Number:
AG003T2N
Chemical Name:
Nialamide
CAS Number:
51-12-7
Molecular Formula:
C16H18N4O2
Molecular Weight:
298.3397
MDL Number:
MFCD00010106
IUPAC Name:
N-benzyl-3-[2-(pyridine-4-carbonyl)hydrazinyl]propanamide
InChI:
InChI=1S/C16H18N4O2/c21-15(18-12-13-4-2-1-3-5-13)8-11-19-20-16(22)14-6-9-17-10-7-14/h1-7,9-10,19H,8,11-12H2,(H,18,21)(H,20,22)
InChI Key:
NOIIUHRQUVNIDD-UHFFFAOYSA-N
SMILES:
O=C(NCc1ccccc1)CCNNC(=O)c1ccncc1
EC Number:
200-079-3
UNII:
T2Q0RYM725
Properties
Complexity:
350  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
298.143g/mol
Formal Charge:
0
Heavy Atom Count:
22  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
3  
Isotope Atom Count:
0
Molecular Weight:
298.346g/mol
Monoisotopic Mass:
298.143g/mol
Rotatable Bond Count:
7  
Topological Polar Surface Area:
83.1A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
0.9  
Literature
Title Journal
Potential repurposing of known drugs as potent bacterial β-glucuronidase inhibitors. Journal of biomolecular screening 20120801
Molecular determinants of ligand selectivity for the human multidrug and toxin extruder proteins MATE1 and MATE2-K. The Journal of pharmacology and experimental therapeutics 20120601
Fictive locomotion in the adult decerebrate and spinal mouse in vivo. The Journal of physiology 20120115
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). PLoS computational biology 20111201
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. Bioorganic & medicinal chemistry letters 20101101
Research on antidepressants in India. Indian journal of psychiatry 20100101
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum. Nature chemical biology 20091001
Development and validation of a hydrophilic interaction liquid chromatography-tandem mass spectrometry method for determination of isoniazid in human plasma. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090115
Signatures of depression in non-stationary biometric time series. Computational intelligence and neuroscience 20090101
Preproenkephalin knockout mice show no depression-related phenotype. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20071101
[Pharmacologic correction of psycho-emotive disorders in the rehabilitation of patients after removal of brain tumors]. Voprosy onkologii 20070101
Microsphere-based protease assays and screening application for lethal factor and factor Xa. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells. The Journal of biological chemistry 20020419
Parallel nociceptive reflex pathways with negative and positive feedback functions to foot extensors in the cat. The Journal of physiology 20011015
[Clinical studies of cochleotoxicosis due to viomycin and kanamycin during tuberculostatic treatment (a prophylactic attempt)]. Monatsschrift fur Ohrenheilkunde und Laryngo-Rhinologie 19680101
Effect of certain monoamine oxidase inhibitors on isoproterenol-induced cardiac necrosis in rats. Proceedings of the Western Pharmacology Society 19660101
Intramuscular nialamide in intractable depression. Diseases of the nervous system 19651201
[TREATMENT OF DEPRESSIVE STATES WITH INTRAVENOUS NIAMIDE]. Toulouse medical 19641201
Nialamide for the treatment of anergy and depression. Diseases of the nervous system 19590801
Properties