Home Carboxys (2S)-1-acetylpyrrolidine-2-carboxylic acid

(2S)-1-acetylpyrrolidine-2-carboxylic acid

CAS No.:
68-95-1
Catalog Number:
AG003SP3
Molecular Formula:
C7H11NO3
Molecular Weight:
157.1671
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5g
97%
In Stock USA
United States
$13
- +
25g
97%
In Stock USA
United States
$25
- +
100g
97%
In Stock USA
United States
$88
- +
500g
97%
In Stock USA
United States
$300
- +
Product Description
Catalog Number:
AG003SP3
Chemical Name:
(2S)-1-acetylpyrrolidine-2-carboxylic acid
CAS Number:
68-95-1
Molecular Formula:
C7H11NO3
Molecular Weight:
157.1671
MDL Number:
MFCD00020837
IUPAC Name:
(2S)-1-acetylpyrrolidine-2-carboxylic acid
InChI:
InChI=1S/C7H11NO3/c1-5(9)8-4-2-3-6(8)7(10)11/h6H,2-4H2,1H3,(H,10,11)/t6-/m0/s1
InChI Key:
GNMSLDIYJOSUSW-LURJTMIESA-N
SMILES:
CC(=O)N1CCC[C@H]1C(=O)O
EC Number:
200-698-9
UNII:
CC8XZ138VZ
Properties
Complexity:
190  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Defined Bond Stereocenter Count:
0
Exact Mass:
157.074g/mol
Formal Charge:
0
Heavy Atom Count:
11  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
157.169g/mol
Monoisotopic Mass:
157.074g/mol
Rotatable Bond Count:
1  
Topological Polar Surface Area:
57.6A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-0.7  
Literature
Title Journal
Radicals formed in N-acetylproline by electron attachment: electron spin resonance spectroscopy and computational studies. The journal of physical chemistry. B 20111215
The influence of the peptide bond on the conformation of amino acids: a theoretical and FT-IR matrix-isolation study of N-acetylproline. Biophysical chemistry 20111201
N-acetylated Proline-Glycine-Proline induced G-protein dependent chemotaxis of neutrophils is independent of CXCL8 release. European journal of pharmacology 20111015
CXCR2 antagonists block the N-Ac-PGP-induced neutrophil influx in the airways of mice, but not the production of the chemokine CXCL1. European journal of pharmacology 20111015
A CXCL8 receptor antagonist based on the structure of N-acetyl-proline-glycine-proline. European journal of pharmacology 20111015
Valence anions of N-acetylproline in the gas phase: computational and anion photoelectron spectroscopic studies. The Journal of chemical physics 20110921
A self-propagating matrix metalloprotease-9 (MMP-9) dependent cycle of chronic neutrophilic inflammation. PloS one 20110101
The collagen-breakdown product N-acetyl-Proline-Glycine-Proline (N-alpha-PGP) does not interact directly with human CXCR1 and CXCR2. European journal of pharmacology 20100915
Anti-proline-glycine-proline or antielastin autoantibodies are not evident in chronic inflammatory lung disease. American journal of respiratory and critical care medicine 20100101
Proline-Glycine-Proline (PGP) and High Mobility Group Box Protein-1 (HMGB1): Potential Mediators of Cystic Fibrosis Airway Inflammation. The open respiratory medicine journal 20100101
Quantum mechanical and NMR studies of ring puckering and cis/trans-rotameric interconversion in prolines and hydroxyprolines. The journal of physical chemistry. A 20091008
A proline-based neuraminidase inhibitor: DFT studies on the zwitterion conformation, stability and formation. International journal of molecular sciences 20090901
Identification of N-acetyl Proline-Glycine-Proline (acPGP) in human serum of adults and newborns by liquid chromatography-tandem mass spectrometry. Clinica chimica acta; international journal of clinical chemistry 20090401
Mechanism of action of cyclophilin a explored by metadynamics simulations. PLoS computational biology 20090301
Simultaneous measurement of proline and related compounds in oak leaves by high-performance ligand-exchange chromatography and electrospray ionization mass spectrometry for environmental stress studies. Journal of chromatography. A 20090213
N-alpha-PGP and PGP, potential biomarkers and therapeutic targets for COPD. Respiratory research 20090101
Induction of lung emphysema is prevented by L-arginine-threonine-arginine. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20080901
Interfering with extracellular matrix degradation to blunt inflammation. Current opinion in pharmacology 20080601
Modeling the solvation of peptides. The case of (s)-N-acetylproline amide in liquid water. The journal of physical chemistry. B 20080320
Conformational analysis of L-prolines in water. The journal of physical chemistry. B 20071220
Structure of N-acetylproline amide in liquid water: experimentally measured and numerically simulated infrared and vibrational circular dichroism spectra. The journal of physical chemistry. B 20060928
Theoretical and experimental investigation of the energetics of cis-trans proline isomerization in peptide models. The journal of physical chemistry. A 20060525
Microsphere-based protease assays and screening application for lethal factor and factor Xa. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
A novel peptide CXCR ligand derived from extracellular matrix degradation during airway inflammation. Nature medicine 20060301
The matrix degrades, neutrophils invade. Nature medicine 20060301
Purification and characterization of a novel aminoacylase from Streptomyces mobaraensis. Bioscience, biotechnology, and biochemistry 20051001
Protein heterodimerization through ligand-bridged multivalent pre-organization: enhancing ligand binding toward both protein targets. Journal of the American Chemical Society 20050223
The effect of penetration enhancers on drug delivery through skin: a QSAR study. Journal of controlled release : official journal of the Controlled Release Society 20040914
Theoretical calculations of infrared absorption, vibrational circular dichroism, and two-dimensional vibrational spectra of acetylproline in liquids water and chloroform. The Journal of chemical physics 20040722
Crystal structure of carbapenem synthase (CarC). The Journal of biological chemistry 20030606
Inhibitory effect of a complementary peptide on ulceration in the alkali-injured rabbit cornea. Investigative ophthalmology & visual science 20011101
NMR conformational analysis of cis and trans proline isomers in the neutrophil chemoattractant, N-acetyl-proline-glycine-proline. Biopolymers 20010501
Properties