Raman and IR spectroscopic studies of fenamates--conformational differences in polymorphs of flufenamic acid, mefenamic acid and tolfenamic acid.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20121001

Tolfenamic acid suppresses cytochrome P450 2E1 expression in mouse liver.

Integrative biology : quantitative biosciences from nano to macro 20120921

Development and validation of two multiresidue liquid chromatography tandem mass spectrometry methods based on a versatile extraction procedure for isolating non-steroidal anti-inflammatory drugs from bovine milk and muscle tissue.

Analytical and bioanalytical chemistry 20120901

Determination of non-steroidal anti-inflammatory drugs and their metabolites in milk by liquid chromatography-tandem mass spectrometry.

Analytical and bioanalytical chemistry 20120701

Structural features of mono- and tri-nuclear Zn(II) complexes with a non-steroidal anti-inflammatory drug as ligand.

Dalton transactions (Cambridge, England : 2003) 20120621

Chemopreventive effects of tolfenamic acid against esophageal tumorigenesis in rats.

Investigational new drugs 20120601

Italian guidelines for primary headaches: 2012 revised version.

The journal of headache and pain 20120501

Selective inhibition of human type-5 17β-hydroxysteroid dehydrogenase (AKR1C3) by baccharin, a component of Brazilian propolis.

Journal of natural products 20120427

Evaluating the effects of 14-day oral vedaprofen and tolfenamic acid treatment on renal function, hematological and biochemical profiles in healthy cats.

Journal of veterinary pharmacology and therapeutics 20120201

Polymorph formation and nucleation mechanism of tolfenamic acid in solution: an investigation of pre-nucleation solute association.

Pharmaceutical research 20120201

Cobalt(II) complexes with non-steroidal anti-inflammatory drug tolfenamic acid: Structure and biological evaluation.

European journal of medicinal chemistry 20120201

Activating transcription factor 3 and the nervous system.

Frontiers in molecular neuroscience 20120101

Tolfenamic acid induces apoptosis and growth inhibition in head and neck cancer: involvement of NAG-1 expression.

PloS one 20120101

Effect of tolfenamic acid on canine cancer cell proliferation, specificity protein (sp) transcription factors, and sp-regulated proteins in canine osteosarcoma, mammary carcinoma, and melanoma cells.

Journal of veterinary internal medicine 20120101

Modulation of the activity of Sp transcription factors by mithramycin analogues as a new strategy for treatment of metastatic prostate cancer.

PloS one 20120101

Expression of specificity protein transcription factors in pancreatic cancer and their association in prognosis and therapy.

Current medicinal chemistry 20120101

Anti-inflammatory drugs and prediction of new structures by comparative analysis.

Anti-inflammatory & anti-allergy agents in medicinal chemistry 20120101

9,10-phenanthrenequinone induces monocytic differentiation of U937 cells through regulating expression of aldo-keto reductase 1C3.

Biological & pharmaceutical bulletin 20120101

The ability of tolfenamic acid to penetrate the brain: a model for testing the brain disposition of candidate Alzheimer's drugs using multiple platforms.

Current Alzheimer research 20111201

Interplay between molecular conformation and intermolecular interactions in conformational polymorphism: a molecular perspective from electronic calculations of tolfenamic acid.

International journal of pharmaceutics 20111014

Nonsteroidal anti-inflammatory drug flufenamic acid is a potent activator of AMP-activated protein kinase.

The Journal of pharmacology and experimental therapeutics 20111001

Development and validation of a confirmatory method for the determination of 12 non steroidal anti-inflammatory drugs in milk using liquid chromatography-tandem mass spectrometry.

Journal of chromatography. A 20110916

Pharmacokinetic and pharmacodynamic modelling of marbofloxacin administered alone and in combination with tolfenamic acid in calves.

Journal of veterinary pharmacology and therapeutics 20110801

Optimization of the derivatization reaction and the solid-phase microextraction conditions using a D-optimal design and three-way calibration in the determination of non-steroidal anti-inflammatory drugs in bovine milk by gas chromatography-mass spectrometry.

Journal of chromatography. A 20110715

Inhibition of myeloid cell leukemia-1 by tolfenamic acid induces apoptosis in mucoepidermoid carcinoma.

Oral diseases 20110701

Tolfenamic acid inhibits ovarian cancer cell growth and decreases the expression of c-Met and survivin through suppressing specificity protein transcription factors.

Gynecologic oncology 20110701

Tolfenamic acid interrupts the de novo synthesis of the β-amyloid precursor protein and lowers amyloid beta via a transcriptional pathway.

Current Alzheimer research 20110601

Roles of rat and human aldo-keto reductases in metabolism of farnesol and geranylgeraniol.

Chemico-biological interactions 20110530

Apoptotic effect of tolfenamic acid in androgen receptor-independent prostate cancer cell and xenograft tumor through specificity protein 1.

Cancer science 20110401

Combined treatment of pancreatic cancer with mithramycin a and tolfenamic Acid promotes sp1 degradation and synergistic antitumor activity--letter.

Cancer research 20110401

Chemopreventive effect of tolfenamic acid on KB human cervical cancer cells and tumor xenograft by downregulating specificity protein 1.

European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 20110301

Tolfenamic acid decreases c-Met expression through Sp proteins degradation and inhibits lung cancer cells growth and tumor formation in orthotopic mice.

Investigational new drugs 20110201

Therapeutic applications of NSAIDS in cancer: special emphasis on tolfenamic acid.

Frontiers in bioscience (Scholar edition) 20110101

Congenital Pelger-Huët anomaly in a Danish/Swedish Farmdog: case report.

Acta veterinaria Scandinavica 20110101

Combined analgesics in (headache) pain therapy: shotgun approach or precise multi-target therapeutics?

BMC neurology 20110101

Betulinic acid inhibits colon cancer cell and tumor growth and induces proteasome-dependent and -independent downregulation of specificity proteins (Sp) transcription factors.

BMC cancer 20110101

Enhanced anticancer activity of gemcitabine in combination with noscapine via antiangiogenic and apoptotic pathway against non-small cell lung cancer.

PloS one 20110101

Development of a list of potentially inappropriate drugs for the korean elderly using the delphi method.

Healthcare informatics research 20101201

Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Bioorganic & medicinal chemistry letters 20101101

Postoperative analgesic efficacy of meloxicam compared to tolfenamic acid in cats undergoing orthopaedic surgery.

The Journal of small animal practice 20101001

Activating transcription factor 2 (ATF2) controls tolfenamic acid-induced ATF3 expression via MAP kinase pathways.

Oncogene 20100916

Occurrence and risk assessment of acidic pharmaceuticals in the Yellow River, Hai River and Liao River of north China.

The Science of the total environment 20100715

Analytical strategy for the determination of non-steroidal anti-inflammatory drugs in plasma and improved analytical strategy for the determination of authorized and non-authorized non-steroidal anti-inflammatory drugs in milk by LC-MS/MS.

Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20100701

Apoptotic Effect of Tolfenamic Acid in KB Human Oral Cancer Cells: Possible Involvement of the p38 MAPK Pathway.

Journal of clinical biochemistry and nutrition 20100701

Novel milk-based oral formulations: proof of concept.

International journal of pharmaceutics 20100510

Pharmacokinetic and pharmacodynamic modelling of marbofloxacin administered alone and in combination with tolfenamic acid in goats.

Veterinary journal (London, England : 1997) 20100501

Confirmatory analysis of non-steroidal anti-inflammatory drugs in bovine milk by high-performance liquid chromatography with fluorescence detection.

Journal of chromatography. A 20100423

Bismuth(III) complexes derived from non-steroidal anti-inflammatory drugs and their activity against Helicobacter pylori.

Dalton transactions (Cambridge, England : 2003) 20100321

Combined treatment of pancreatic cancer with mithramycin A and tolfenamic acid promotes Sp1 degradation and synergistic antitumor activity.

Cancer research 20100201

Effect of preventive (beta blocker) treatment, behavioural migraine management, or their combination on outcomes of optimised acute treatment in frequent migraine: randomised controlled trial.

BMJ (Clinical research ed.) 20100101

Thermodynamic and structural study of tolfenamic acid polymorphs.

Journal of pharmaceutical and biomedical analysis 20091205

Development of a rapid, multi-class method for the confirmatory analysis of anti-inflammatory drugs in bovine milk using liquid chromatography tandem mass spectrometry.

Journal of chromatography. A 20091113

Eicosanoids influence insect susceptibility to nucleopolyhedroviruses.

Journal of invertebrate pathology 20091101

Tolfenamic acid inhibits esophageal cancer through repression of specificity proteins and c-Met.

Carcinogenesis 20090701

Anti-inflammatory, antiproliferative, and radical-scavenging activities of tolfenamic acid and its metal complexes.

Chemistry & biodiversity 20090601

The nonsteroidal anti-inflammatory drug tolfenamic acid inhibits BT474 and SKBR3 breast cancer cell and tumor growth by repressing erbB2 expression.

Molecular cancer therapeutics 20090501

The relationship between diphenylamine structure and NSAIDs-induced hepatocytes injury.

Toxicology letters 20090425

Polymer-induced heteronucleation of tolfenamic acid: structural investigation of a pentamorph.

Journal of the American Chemical Society 20090408

Tolfenamic acid enhances pancreatic cancer cell and tumor response to radiation therapy by inhibiting survivin protein expression.

Molecular cancer therapeutics 20090301

Thermodynamics of lipophilic drug binding to intestinal fatty acid binding protein and permeation across membranes.

Molecular pharmaceutics 20090101

Investigating AP-2 and YY1 protein expression as a cause of high HER2 gene transcription in breast cancers with discordant HER2 gene amplification.

Breast cancer research : BCR 20090101

Regulation of HIV-1 transcription in cells of the monocyte-macrophage lineage.

Retrovirology 20090101

ESE-1/EGR-1 pathway plays a role in tolfenamic acid-induced apoptosis in colorectal cancer cells.

Molecular cancer therapeutics 20081201

Current migraine management - patient acceptability and future approaches.

Neuropsychiatric disease and treatment 20081201

Efficacy of tolfenamic acid and meloxicam in the control of postoperative pain following ovariohysterectomy in the cat.

Veterinary anaesthesia and analgesia 20081101

Assessment of the duration of the pain response associated with lameness in dairy cows, and the influence of treatment.

New Zealand veterinary journal 20081001

Optimizing prophylactic treatment of migraine: Subtypes and patient matching.

Therapeutics and clinical risk management 20081001

Poloxamer 407 as a solubilising agent for tolfenamic acid and as a base for a gel formulation.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20080902

Effects of meloxicam or tolfenamic acid administration on the pain and stress responses of Merino lambs to mulesing.

Australian veterinary journal 20080801

In vitro inhibition of CYP1A2 by model inhibitors, anti-inflammatory analgesics and female sex steroids: predictability of in vivo interactions.

Basic & clinical pharmacology & toxicology 20080801

Effects of fenamate on inhibitory postsynaptic currents in Purkinje's cells.

Bulletin of experimental biology and medicine 20080501

catena-Poly[[bis-[2-(2,3-dimethyl-anilino)benzoato-κO]cadmium(II)]-di-μ-3-pyridylmethanol-κN:O;κO:N].

Acta crystallographica. Section E, Structure reports online 20080301

The effect of suspended particles coated by humic acid on the toxicity of pharmaceuticals, estrogens, and phenolic compounds.

Environment international 20080201

Confirmatory identification of sixteen non-steroidal anti-inflammatory drug residues in raw milk by liquid chromatography coupled with ion trap mass spectrometry.

Rapid communications in mass spectrometry : RCM 20080101

Field evaluation of the efficacy of tolfenamic acid administered in one single preoperative injection for the prevention of postoperative pain in the dog.

Journal of veterinary pharmacology and therapeutics 20071201

Inhibition of human thiopurine S-methyltransferase by various nonsteroidal anti-inflammatory drugs in vitro: a mechanism for possible drug interactions.

Drug metabolism and disposition: the biological fate of chemicals 20070901

Tolfenamic acid is a potent CYP1A2 inhibitor in vitro but does not interact in vivo: correction for protein binding is needed for data interpretation.

European journal of clinical pharmacology 20070901

Nonsteroidal anti-inflammatory drugs in cats: a review.

Veterinary anaesthesia and analgesia 20070701

Eicosanoid biosynthesis inhibitors increase the susceptibility of Lymantria dispar to nucleopolyhedrovirus LdMNPV.

Journal of invertebrate pathology 20070601

Acute migraine: Current treatment and emerging therapies.

Therapeutics and clinical risk management 20070601

Regulation of vascular endothelial growth factor receptor-1 expression by specificity proteins 1, 3, and 4 in pancreatic cancer cells.

Cancer research 20070401

Structure-based inhibitor design for an enzyme that binds different steroids: a potent inhibitor for human type 5 17beta-hydroxysteroid dehydrogenase.

The Journal of biological chemistry 20070316

Rapid method for the determination of non-steroidal anti-inflammatory drugs in animal tissue by liquid chromatography-mass spectrometry with ion-trap detector.

Analytica chimica acta 20070314

Characterization and physical stability of tolfenamic acid-PVP K30 solid dispersions.

Pharmaceutical development and technology 20070101

The use of combination therapies in the acute management of migraine.

Neuropsychiatric disease and treatment 20060901

Nutraceutical inhibitors of urokinase: potential applications in prostate cancer prevention and treatment.

Oncology reports 20060801

Tolfenamic acid and pancreatic cancer growth, angiogenesis, and Sp protein degradation.

Journal of the National Cancer Institute 20060621

Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Involvement of opioidergic and alpha2-adrenergic mechanisms in the central analgesic effects of non-steroidal anti-inflammatory drugs in sheep.

Research in veterinary science 20060401

Pharmacokinetic and pharmacodynamic interactions of tolfenamic acid and marbofloxacin in goats.

Research in veterinary science 20060201

Determination of fourteen non-steroidal anti-inflammatory drugs in animal serum and plasma by liquid chromatography/mass spectrometry.

Rapid communications in mass spectrometry : RCM 20060101

Multi-residue determination of non-steroidal anti-inflammatory drug residues in animal serum and plasma by HPLC and photo-diode array detection.

Journal of chromatographic science 20060101

Interventions for preventing or treating alcohol hangover: systematic review of randomised controlled trials.

BMJ (Clinical research ed.) 20051224

Nitric oxide releasing derivatives of tolfenamic acid with anti-inflammatory activity and safe gastrointestinal profile.

Bioorganic & medicinal chemistry 20051201

Study of structural features and thermodynamic parameters, determining the chromatographic behaviour of drug-cyclodextrin complexes.

Journal of chromatography. A 20050916

Prediction of genotoxicity of chemical compounds by statistical learning methods.

Chemical research in toxicology 20050601

Geriatric pharmacology.

The Veterinary clinics of North America. Small animal practice 20050501

Infrared studies of the polymorphic states of the fenamates.

Journal of pharmaceutical and biomedical analysis 20050309

Influence of marbofloxacin on the pharmacokinetics and pharmacodynamics of tolfenamic acid in calves.

Journal of veterinary pharmacology and therapeutics 20050201

PK-PD integration and PK-PD modelling of nonsteroidal anti-inflammatory drugs: principles and applications in veterinary pharmacology.

Journal of veterinary pharmacology and therapeutics 20041201

Compounds exhibiting selective efficacy for different beta subunits of human recombinant gamma-aminobutyric acid A receptors.

The Journal of pharmacology and experimental therapeutics 20041101

Pain management in cats--past, present and future. Part 2. Treatment of pain--clinical pharmacology.

Journal of feline medicine and surgery 20041001

Synthesis and pharmacological evaluation of amide conjugates of NSAIDs with L-cysteine ethyl ester, combining potent antiinflammatory and antioxidant properties with significantly reduced gastrointestinal toxicity.

Bioorganic & medicinal chemistry letters 20040716

Attitudes and concerns of French veterinarians towards pain and analgesia in dogs and cats.

Veterinary anaesthesia and analgesia 20040701

Determination of expression of cyclooxygenase-1 and -2 isozymes in canine tissues and their differential sensitivity to nonsteroidal anti-inflammatory drugs.

American journal of veterinary research 20040601

Migraine headache.

Clinical evidence 20040601

Binuclear copper(II) complexes of tolfenamic: synthesis, crystal structure, spectroscopy and superoxide dismutase activity.

Journal of inorganic biochemistry 20040201

Acute treatment of migraine. Breaking the paradigm of monotherapy.

BMC neurology 20040101

Rizatriptan versus rizatriptan plus rofecoxib versus rizatriptan plus tolfenamic acid in the acute treatment of migraine.

BMC neurology 20040101

Multi-residue liquid chromatography/tandem mass spectrometry method for the detection of non-steroidal anti-inflammatory drugs in bovine muscle: optimisation of ion trap parameters.

Rapid communications in mass spectrometry : RCM 20040101

Migraine headache.

Clinical evidence 20031201

Risk of cancer in a large cohort of nonaspirin NSAID users: a population-based study.

British journal of cancer 20030602

Determination of acidic drugs in sewage water by gas chromatography-mass spectrometry as tert.-butyldimethylsilyl derivatives.

Journal of chromatography. A 20030124

[Neurotransmitter mechanism of the tropoxin effect in comparison with other antimigraine preparations].

Eksperimental'naia i klinicheskaia farmakologiia 20030101

[Effectiveness of tolfenamic acid in the prevention of migraine].

Medicina (Kaunas, Lithuania) 20020101

Search of antimicrobial activity of selected non-antibiotic drugs.

Acta poloniae pharmaceutica 20020101

Intercalation and controlled release of pharmaceutically active compounds from a layered double hydroxide.

Chemical communications (Cambridge, England) 20011121

Fenamates stimulate BKCa channel osteoblast-like MG-63 cells activity in the human.

Journal of investigative medicine : the official publication of the American Federation for Clinical Research 20011101

Dexamethasone decreases migraine recurrence observed after treatment with a triptan combined with a nonsteroidal anti-inflammatory drug.

Arquivos de neuro-psiquiatria 20010901

Screening procedure for detection of non-steroidal anti-inflammatory drugs and their metabolites in urine as part of a systematic toxicological analysis procedure for acidic drugs and poisons by gas chromatography-mass spectrometry after extractive methylation.

Journal of analytical toxicology 20010101

A nonsteroidal anti-inflammatory drug, flufenamic acid, inhibits the expression of the androgen receptor in LNCaP cells.

Endocrinology 19991101

Human pharmacokinetics of tolfenamic acid, a new anti-inflammatory agent.

European journal of clinical pharmacology 19810101