Methyl methanesulfonate
| Title | Journal |
|---|---|
| A novel, integrated in vitro carcinogenicity test to identify genotoxic and non-genotoxic carcinogens using human lymphoblastoid cells. | Archives of toxicology 20180101 |
| Genotoxic effect and rat hepatocyte death occurred after oxidative stress induction and antioxidant gene downregulation caused by long term fluoride exposure. | Chemico-biological interactions 20170225 |
| RNA sequencing provides insights into the toxicogenomic response of ZF4 cells to methyl methanesulfonate. | Journal of applied toxicology : JAT 20160101 |
| Repairing of N-mustard derivative BO-1055 induced DNA damage requires NER, HR, and MGMT-dependent DNA repair mechanisms. | Oncotarget 20150922 |
| Acute dosing and p53-deficiency promote cellular sensitivity to DNA methylating agents. | Toxicological sciences : an official journal of the Society of Toxicology 20150401 |
| Profiling dose-dependent activation of p53-mediated signaling pathways by chemicals with distinct mechanisms of DNA damage. | Toxicological sciences : an official journal of the Society of Toxicology 20141101 |
| Expression and localization of GEN1 in mouse mammary epithelial cells. | Journal of biochemical and molecular toxicology 20141001 |
| Hypoxia provokes base excision repair changes and a repair-deficient, mutator phenotype in colorectal cancer cells. | Molecular cancer research : MCR 20141001 |
| The γH2AX assay for genotoxic and nongenotoxic agents: comparison of H2AX phosphorylation with cell death response. | Toxicological sciences : an official journal of the Society of Toxicology 20140701 |
| Utilization of CDKN1A/p21 gene for class discrimination of DNA damage-induced clastogenicity. | Toxicology 20140106 |
| Characterization of formaldehyde's genotoxic mode of action by gene expression analysis in TK6 cells. | Archives of toxicology 20131101 |
| Efficient monitoring of in vivo pig-a gene mutation and chromosomal damage: summary of 7 published studies and results from 11 new reference compounds. | Toxicological sciences : an official journal of the Society of Toxicology 20121201 |
| Evaluation of mutagenic and antimutagenic activities of oligorutin and oligoesculin. | Food chemistry 20121201 |
| Interactions of sulforaphane and dimethyl sulfoxide with methyl methanesulfonate, urethane, 4-nitroquinoline-1-oxide and hydrogen peroxide in the Drosophila melanogaster wing spot test. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20121201 |
| Sea urchin coelomocytes are resistant to a variety of DNA damaging agents. | Aquatic toxicology (Amsterdam, Netherlands) 20121115 |
| Interaction of S-methyl methanethiosulfonate with DPPC bilayer. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20121101 |
| A co-culture system of human intestinal Caco-2 cells and lymphoblastoid TK6 cells for investigating the genotoxicity of oral compounds. | Mutagenesis 20121101 |
| Insensitivity of the in vitro cytokinesis-block micronucleus assay with human lymphocytes for the detection of DNA damage present at the start of the cell culture. | Mutagenesis 20121101 |
| Comparative analyses of the two proliferating cell nuclear antigens from the hyperthermophilic archaeon, Thermococcus kodakarensis. | Genes to cells : devoted to molecular & cellular mechanisms 20121101 |
| DNA strand breaks detected in embryos of the adult snails, Potamopyrgus antipodarum, and in neonates exposed to genotoxic chemicals. | Aquatic toxicology (Amsterdam, Netherlands) 20121015 |
| Recruitment of HRDC domain of WRN and BLM to the sites of DNA damage induced by mitomycin C and methyl methanesulfonate. | Cell biology international 20121001 |
| Evaluation of cytotoxic, genotoxic and antigenotoxic potential of Solanum lycocarpum fruits glicoalkaloid extract in V79 cells. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20121001 |
| The effects of urbanization on Lepomis macrochirus using the comet assay. | Ecotoxicology and environmental safety 20121001 |
| Two serine phosphorylation sites in the C-terminus of Rad9 are critical for 9-1-1 binding to TopBP1 and activation of the DNA damage checkpoint response in HeLa cells. | Genes to cells : devoted to molecular & cellular mechanisms 20121001 |
| ddm1 plants are sensitive to methyl methane sulfonate and NaCl stresses and are deficient in DNA repair. | Plant cell reports 20120901 |
| Saccharomyces cerevisiae Apn1 mutation affecting stable protein expression mimics catalytic activity impairment: implications for assessing DNA repair capacity in humans. | DNA repair 20120901 |
| Polynucleotide kinase/phosphatase, Pnk1, is involved in base excision repair in Schizosaccharomyces pombe. | DNA repair 20120801 |
| Oxidants and not alkylating agents induce rapid mtDNA loss and mitochondrial dysfunction. | DNA repair 20120801 |
| N-methylpurine DNA glycosylase inhibits p53-mediated cell cycle arrest and coordinates with p53 to determine sensitivity to alkylating agents. | Cell research 20120801 |
| Baccharin prevents genotoxic effects induced by methyl methanesulfonate and hydrogen peroxide in V79 cells. | Journal of food science 20120801 |
| Loss of a 20S proteasome activator in Saccharomyces cerevisiae downregulates genes important for genomic integrity, increases DNA damage, and selectively sensitizes cells to agents with diverse mechanisms of action. | G3 (Bethesda, Md.) 20120801 |
| DNA cleavage induced by antitumor antibiotic leinamycin and its biological consequences. | Bioorganic & medicinal chemistry 20120715 |
| Human POLB gene is mutated in high percentage of colorectal tumors. | The Journal of biological chemistry 20120706 |
| Evolution of a membrane protein regulon in Saccharomyces. | Molecular biology and evolution 20120701 |
| Reversal of PCNA ubiquitylation by Ubp10 in Saccharomyces cerevisiae. | PLoS genetics 20120701 |
| A novel acetylation cycle of transcription co-activator Yes-associated protein that is downstream of Hippo pathway is triggered in response to SN2 alkylating agents. | The Journal of biological chemistry 20120622 |
| Cytogenetic damage induced by mouthrinses formulations in vivo and in vitro. | Clinical oral investigations 20120601 |
| p53-Independent expression of wild-type p53-induced phosphatase 1 (Wip1) in methylmethane sulfonate-treated cancer cell lines and human tumors. | The international journal of biochemistry & cell biology 20120601 |
| CinA is regulated via ComX to modulate genetic transformation and cell viability in Streptococcus mutans. | FEMS microbiology letters 20120601 |
| A conserved function for the H2A.Z C terminus. | The Journal of biological chemistry 20120601 |
| Deregulated expression of DNA polymerase β is involved in the progression of genomic instability. | Environmental and molecular mutagenesis 20120601 |
| A broad requirement for TLS polymerases η and κ, and interacting sumoylation and nuclear pore proteins, in lesion bypass during C. elegans embryogenesis. | PLoS genetics 20120601 |
| Brassica oleracea L. Var. costata DC and Pieris brassicae L. aqueous extracts reduce methyl methanesulfonate-induced DNA damage in V79 hamster lung fibroblasts. | Journal of agricultural and food chemistry 20120530 |
| Clustered mutations in yeast and in human cancers can arise from damaged long single-strand DNA regions. | Molecular cell 20120525 |
| Cytotoxic and genotoxic effects of cylindrospermopsin in mice treated by gavage or intraperitoneal injection. | Environmental toxicology 20120501 |
| Trypanosomal histone γH2A and the DNA damage response. | Molecular and biochemical parasitology 20120501 |
| Automated segmentation of comet assay images using Gaussian filtering and fuzzy clustering. | Medical & biological engineering & computing 20120501 |
| Alkbh2 protects against lethality and mutation in primary mouse embryonic fibroblasts. | DNA repair 20120501 |
| Characterization of anti-silencing factor 1 in Leishmania major. | Memorias do Instituto Oswaldo Cruz 20120501 |
| Tyrosyl-DNA phosphodiesterase 1 (TDP1) repairs DNA damage induced by topoisomerases I and II and base alkylation in vertebrate cells. | The Journal of biological chemistry 20120413 |
| Synthesis, biological evaluation, and structure-activity relationships of a novel class of apurinic/apyrimidinic endonuclease 1 inhibitors. | Journal of medicinal chemistry 20120412 |
| DNA replication stress differentially regulates G1/S genes via Rad53-dependent inactivation of Nrm1. | The EMBO journal 20120404 |
| Efficiency and safety of mesh fixation in laparoscopic inguinal hernia repair using n-butyl cyanoacrylate: long-term biocompatibility in over 1,300 mesh fixations. | Hernia : the journal of hernias and abdominal wall surgery 20120401 |
| The region of XRCC1 which harbours the three most common nonsynonymous polymorphic variants, is essential for the scaffolding function of XRCC1. | DNA repair 20120401 |
| Alkylation-induced genotoxicity as a predictor of DNA repair deficiency following experimental oral carcinogenesis. | Journal of molecular histology 20120401 |
| Cloning, overexpression and characterization of Leishmania donovani triosephosphate isomerase. | Experimental parasitology 20120401 |
| Competition between replicative and translesion polymerases during homologous recombination repair in Drosophila. | PLoS genetics 20120401 |
| A new role for translation initiation factor 2 in maintaining genome integrity. | PLoS genetics 20120401 |
| The DSIF subunits Spt4 and Spt5 have distinct roles at various phases of immunoglobulin class switch recombination. | PLoS genetics 20120401 |
| PP4 dephosphorylates Maf1 to couple multiple stress conditions to RNA polymerase III repression. | The EMBO journal 20120321 |
| The impact of cyclin-dependent kinase 5 depletion on poly(ADP-ribose) polymerase activity and responses to radiation. | Cellular and molecular life sciences : CMLS 20120301 |
| In vitro genotoxicity evaluation of 4-carboxyl-2,6-dinitrophenylazohydroxynaphthalenes using human lymphocytes. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120301 |
| Comet assay analysis of DNA damage in T- and B-lymphocytes separated by MACS for human biomonitoring studies. | Toxicology in vitro : an international journal published in association with BIBRA 20120301 |
| Increased PARP-1 association with DNA in alkylation damaged, PARP-inhibited mouse fibroblasts. | Molecular cancer research : MCR 20120301 |
| DNA damage by X-rays and their impact on replication processes. | Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20120301 |
| In vitro bioassay for reactive toxicity towards proteins implemented for water quality monitoring. | Journal of environmental monitoring : JEM 20120301 |
| PTEN deletion in prostate cancer cells does not associate with loss of RAD51 function: implications for radiotherapy and chemotherapy. | Clinical cancer research : an official journal of the American Association for Cancer Research 20120215 |
| The TM2 6' position of GABA(A) receptors mediates alcohol inhibition. | The Journal of pharmacology and experimental therapeutics 20120201 |
| Posttranslational modifications of proteins in the pathobiology of medically relevant fungi. | Eukaryotic cell 20120201 |
| Detection of 8-oxodG in Dreissena polymorpha gill cells exposed to model contaminants. | Mutation research 20120124 |
| Identification of early target genes of aflatoxin B1 in human hepatocytes, inter-individual variability and comparison with other genotoxic compounds. | Toxicology and applied pharmacology 20120115 |
| DNA alkylation lesions and their repair in human cells: modification of the comet assay with 3-methyladenine DNA glycosylase (AlkD). | Toxicology letters 20120105 |
| The ToxTracker assay: novel GFP reporter systems that provide mechanistic insight into the genotoxic properties of chemicals. | Toxicological sciences : an official journal of the Society of Toxicology 20120101 |
| Simultaneous quantification of methylated purines in DNA by isotope dilution LC-MS/MS coupled with automated solid-phase extraction. | Analytical and bioanalytical chemistry 20120101 |
| Differential network biology. | Molecular systems biology 20120101 |
| Histone chaperone Asf1 plays an essential role in maintaining genomic stability in fission yeast. | PloS one 20120101 |
| Novel AlkB dioxygenases--alternative models for in silico and in vivo studies. | PloS one 20120101 |
| Using DNA damage sensitivity phenotypes to characterize mutations affecting proteasome function. | Methods in molecular biology (Clifton, N.J.) 20120101 |
| The two different isoforms of the RSC chromatin remodeling complex play distinct roles in DNA damage responses. | PloS one 20120101 |
| The Smc complexes in DNA damage response. | Cell & bioscience 20120101 |
| Contribution of transcription factor binding site motif variants to condition-specific gene expression patterns in budding yeast. | PloS one 20120101 |
| Detection of PIGO-deficient cells using proaerolysin: a valuable tool to investigate mechanisms of mutagenesis in the DT40 cell system. | PloS one 20120101 |
| Bleomycin sensitivity in Escherichia coli is medium-dependent. | PloS one 20120101 |
| Evolutionary and Biochemical Aspects of Chemical Stress Resistance in Saccharomyces cerevisiae. | Frontiers in genetics 20120101 |
| Cdt1 is differentially targeted for degradation by anticancer chemotherapeutic drugs. | PloS one 20120101 |
| Functional annotation of hierarchical modularity. | PloS one 20120101 |
| Identification of BC005512 as a DNA damage responsive murine endogenous retrovirus of GLN family involved in cell growth regulation. | PloS one 20120101 |
| ScreenTroll: a searchable database to compare genome-wide yeast screens. | Database : the journal of biological databases and curation 20120101 |
| Yeast toxicogenomics: genome-wide responses to chemical stresses with impact in environmental health, pharmacology, and biotechnology. | Frontiers in genetics 20120101 |
| Pph3 dephosphorylation of Rad53 is required for cell recovery from MMS-induced DNA damage in Candida albicans. | PloS one 20120101 |
| Identification of novel human damage response proteins targeted through yeast orthology. | PloS one 20120101 |
| UBR2 of the N-end rule pathway is required for chromosome stability via histone ubiquitylation in spermatocytes and somatic cells. | PloS one 20120101 |
| Protective effects of apigenin against methyl methanesulfonate induced hsp70 expression in the third instar larvae of transgenic Drosophila melanogaster (hsp70-lacZ)Bg(9). | Journal of pharmacology & pharmacotherapeutics 20120101 |
| Localization of the Drosophila Rad9 protein to the nuclear membrane is regulated by the C-terminal region and is affected in the meiotic checkpoint. | PloS one 20120101 |
| Towards a molecular understanding of the fanconi anemia core complex. | Anemia 20120101 |
| Hydroxyurea treatment inhibits proliferation of Cryptococcus neoformans in mice. | Frontiers in microbiology 20120101 |
| Brahmarasayana protects against Ethyl methanesulfonate or Methyl methanesulfonate induced chromosomal aberrations in mouse bone marrow cells. | BMC complementary and alternative medicine 20120101 |
| Reflectance near-infrared spectroscopic method with Chemometric techniques for simultaneous determination of Chondroitin, glucosamine, and methyl sulfonyl methane. | Journal of AOAC International 20120101 |
| Checkpoint kinase ATR phosphorylates Cdt2, a substrate receptor of CRL4 ubiquitin ligase, and promotes the degradation of Cdt1 following UV irradiation. | PloS one 20120101 |
| DNA polymerase α (swi7) and the flap endonuclease Fen1 (rad2) act together in the S-phase alkylation damage response in S. pombe. | PloS one 20120101 |
| Augmenter of liver regeneration (ALR) is a novel biomarker of hepatocellular stress/inflammation: in vitro, in vivo and in silico studies. | Molecular medicine (Cambridge, Mass.) 20120101 |
| Diverse small molecule inhibitors of human apurinic/apyrimidinic endonuclease APE1 identified from a screen of a large public collection. | PloS one 20120101 |
| No role of homologous recombination in dealing with β-lapachone cytotoxicity in yeast. | Chemical research in toxicology 20111219 |
| XRCC1 and base excision repair balance in response to nitric oxide. | DNA repair 20111210 |
| Abundance of prereplicative complexes (Pre-RCs) facilitates recombinational repair under replication stress in fission yeast. | The Journal of biological chemistry 20111202 |
| Development of an efficient gene-targeting system in Aspergillus luchuensis by deletion of the non-homologous end joining system. | Journal of bioscience and bioengineering 20111201 |
| A new high resolution screening method for study of phenotype stress responses of Saccharomyces cerevisae mutants. | Journal of microbiological methods 20111201 |
| Breeding of new strains of mushroom by basidiospore chemical mutagenesis. | Mycobiology 20111201 |
| DNA unwinding by ASCC3 helicase is coupled to ALKBH3-dependent DNA alkylation repair and cancer cell proliferation. | Molecular cell 20111104 |
| Antigenotoxicity of artepillin C in vivo evaluated by the micronucleus and comet assays. | Journal of applied toxicology : JAT 20111101 |
| In vitro primary human lymphocyte flow cytometry based micronucleus assay: simultaneous assessment of cell proliferation, apoptosis and MN frequency. | Mutagenesis 20111101 |
| Protein phosphatase Pph3 and its regulatory subunit Psy2 regulate Rad53 dephosphorylation and cell morphogenesis during recovery from DNA damage in Candida albicans. | Eukaryotic cell 20111101 |
| Diepoxybutane induces the formation of DNA-DNA rather than DNA-protein cross-links, and single-strand breaks and alkali-labile sites in human hepatocyte L02 cells. | Mutation research 20111101 |
| Histone H3K56 acetylation, CAF1, and Rtt106 coordinate nucleosome assembly and stability of advancing replication forks. | PLoS genetics 20111101 |
| Functional relationship between Claspin and Rad17. | Biochemical and biophysical research communications 20111022 |
| Bidirectional resection of DNA double-strand breaks by Mre11 and Exo1. | Nature 20111016 |
| Antigenotoxic and antioxidant activities of palmarosa and citronella essential oils. | Journal of ethnopharmacology 20111011 |
| XRCC1 coordinates disparate responses and multiprotein repair complexes depending on the nature and context of the DNA damage. | Environmental and molecular mutagenesis 20111001 |
| Genotoxicity screening via the γH2AX by flow assay. | Mutation research 20111001 |
| Cellular morphogenesis under stress is influenced by the sphingolipid pathway gene ISC1 and DNA integrity checkpoint genes in Saccharomyces cerevisiae. | Genetics 20111001 |
| A method for detecting genetic toxicity using the RNA synthesis response to DNA damage. | The Journal of toxicological sciences 20111001 |
| Three structure-selective endonucleases are essential in the absence of BLM helicase in Drosophila. | PLoS genetics 20111001 |
| Validation of a genotoxicity test based on p53R2 gene expression in human lymphoblastoid cells. | Mutation research 20110918 |
| DNA site-specific N3-adenine methylation targeted to estrogen receptor-positive cells. | Bioorganic & medicinal chemistry 20110901 |
| Release of Ku and MRN from DNA ends by Mre11 nuclease activity and Ctp1 is required for homologous recombination repair of double-strand breaks. | PLoS genetics 20110901 |
| Effect of methyl methanesulfonate on hsp70 expression and tissue damage in the third instar larvae of transgenic Drosophila melanogaster (hsp70-lacZ) Bg. | Interdisciplinary toxicology 20110901 |
| A synthetic human kinase can control cell cycle progression in budding yeast. | G3 (Bethesda, Md.) 20110901 |
| An in vivo assessment of the genotoxic potential of bisphenol A and 4-tert-octylphenol in rats. | Archives of toxicology 20110801 |
| Delay of gap filling during nucleotide excision repair by base excision repair: the concept of competition exemplified by the effect of propolis. | Toxicological sciences : an official journal of the Society of Toxicology 20110801 |
| Phenylbutyrate inhibits homologous recombination induced by camptothecin and methyl methanesulfonate. | Mutation research 20110801 |
| Repetitive exposure to zinc oxide nanoparticles induces dna damage in human nasal mucosa mini organ cultures. | Environmental and molecular mutagenesis 20110801 |
| Predisposition to cancer caused by genetic and functional defects of mammalian Atad5. | PLoS genetics 20110801 |
| In vivo antigenotoxicity of baccharin, an important constituent of Baccharis dracunculifolia DC (Asteraceae). | Basic & clinical pharmacology & toxicology 20110701 |
| Linking genotoxic responses in Gammarus fossarum germ cells with reproduction impairment, using the Comet assay. | Environmental research 20110701 |
| Genomic profiling uncovers a molecular pattern for toxicological characterization of mutagens and promutagens in vitro. | Toxicological sciences : an official journal of the Society of Toxicology 20110701 |
| Interactions among Trypanosoma brucei RAD51 paralogues in DNA repair and antigenic variation. | Molecular microbiology 20110701 |
| Interrogation of the protein-protein interactions between human BRCA2 BRC repeats and RAD51 reveals atomistic determinants of affinity. | PLoS computational biology 20110701 |
| The cap'n'collar transcription factor Nrf2 mediates both intrinsic resistance to environmental stressors and an adaptive response elicited by chemopreventive agents that determines susceptibility to electrophilic xenobiotics. | Chemico-biological interactions 20110630 |
| A flow cytometry based in vitro micronucleus assay in TK6 cells--validation using early stage pharmaceutical development compounds. | Environmental and molecular mutagenesis 20110601 |
| Fibroblasts from long-lived bird species are resistant to multiple forms of stress. | The Journal of experimental biology 20110601 |
| Low level determinations of methyl methanesulfonate and ethyl methanesulfonate impurities in Lopinavir and Ritonavir Active pharmaceutical ingredients by LC/MS/MS using electrospray ionization. | Journal of pharmaceutical and biomedical analysis 20110515 |
| Sensitive DsRed fluorescence-based reporter cell systems for genotoxicity and oxidative stress assessment. | Mutation research 20110510 |
| Genotoxic evaluation of the insecticide endosulfan based on the induced GADD153-GFP reporter gene expression. | Environmental monitoring and assessment 20110501 |
| Microscreening toxicity system based on living magnetic yeast and gradient chips. | Analytical and bioanalytical chemistry 20110501 |
| Prooxidants prevent yeast cell death induced by genotoxic stress. | Cell biology international 20110501 |
| Protective effect of hawthorn extract against genotoxicity induced by methyl methanesulfonate in human lymphocytes. | Toxicology and industrial health 20110501 |
| Delayed c-Fos activation in human cells triggers XPF induction and an adaptive response to UVC-induced DNA damage and cytotoxicity. | Cellular and molecular life sciences : CMLS 20110501 |
| Are luminescent bacteria suitable for online detection and monitoring of toxic compounds in drinking water and its sources? | Analytical and bioanalytical chemistry 20110501 |
| The influence of scoring method on variability in results obtained with the comet assay. | Mutagenesis 20110501 |
| The Hus1 homologue of Leishmania major encodes a nuclear protein that participates in DNA damage response. | Molecular and biochemical parasitology 20110501 |
| Peptide aptamer mimicking RAD51-binding domain of BRCA2 inhibits DNA damage repair and survival in Trypanosoma brucei. | Microbial pathogenesis 20110501 |
| Global analysis for functional residues of histone variant Htz1 using the comprehensive point mutant library. | Genes to cells : devoted to molecular & cellular mechanisms 20110501 |
| Ixr1 is required for the expression of the ribonucleotide reductase Rnr1 and maintenance of dNTP pools. | PLoS genetics 20110501 |
| Inactivation of chk2 and mus81 leads to impaired lymphocytes development, reduced genomic instability, and suppression of cancer. | PLoS genetics 20110501 |
| SHPRH and HLTF act in a damage-specific manner to coordinate different forms of postreplication repair and prevent mutagenesis. | Molecular cell 20110422 |
| Identification of multiple folding pathways of monellin using pulsed thiol labeling and mass spectrometry. | Biochemistry 20110419 |
| Superoxide dismutase protects cells from DNA damage induced by trivalent methylated arsenicals. | Environmental and molecular mutagenesis 20110401 |
| Antimicrobial, antioxidant, and antimutagenic activities of selected marine natural products and tobacco cembranoids. | Drug and chemical toxicology 20110401 |
| Processing of joint molecule intermediates by structure-selective endonucleases during homologous recombination in eukaryotes. | Chromosoma 20110401 |
| EMSY overexpression disrupts the BRCA2/RAD51 pathway in the DNA-damage response: implications for chromosomal instability/recombination syndromes as checkpoint diseases. | Molecular genetics and genomics : MGG 20110401 |
| A novel nonsense mutation in the APTX gene associated with delayed DNA single-strand break removal fails to enhance sensitivity to different genotoxic agents. | Human mutation 20110401 |
| Sensitive detection of chemical-induced genotoxicity by the Cypridina secretory luciferase reporter assay, using DNA repair-deficient strains of Saccharomyces cerevisiae. | Yeast (Chichester, England) 20110401 |
| Genotoxicity of corrosion eluates obtained from orthodontic brackets in vitro. | American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics 20110401 |
| Alkylation base damage is converted into repairable double-strand breaks and complex intermediates in G2 cells lacking AP endonuclease. | PLoS genetics 20110401 |
| Overcoming temozolomide resistance in glioblastoma via dual inhibition of NAD+ biosynthesis and base excision repair. | Cancer research 20110315 |
| Crucial role for DNA ligase III in mitochondria but not in Xrcc1-dependent repair. | Nature 20110310 |
| Transcriptional regulation by Asf1: new mechanistic insights from studies of the DNA damage response to replication stress. | The Journal of biological chemistry 20110304 |
| SUMO-targeted ubiquitin ligase, Rad60, and Nse2 SUMO ligase suppress spontaneous Top1-mediated DNA damage and genome instability. | PLoS genetics 20110301 |
| Roles of brca2 (fancd1) in oocyte nuclear architecture, gametogenesis, gonad tumors, and genome stability in zebrafish. | PLoS genetics 20110301 |
| The SUMO isopeptidase Ulp2p is required to prevent recombination-induced chromosome segregation lethality following DNA replication stress. | PLoS genetics 20110301 |
| Development and evaluation of human AP endonuclease inhibitors in melanoma and glioma cell lines. | British journal of cancer 20110215 |
| Requirement for NBS1 in the S phase checkpoint response to DNA methylation combined with PARP inhibition. | DNA repair 20110207 |
| DNA double-strand break repair in Caenorhabditis elegans. | Chromosoma 20110201 |
| An evolutionarily acquired genotoxic response discriminates MyoD from Myf5, and differentially regulates hypaxial and epaxial myogenesis. | EMBO reports 20110201 |
| The DNA-binding activity of the Neisseria gonorrhoeae LexA orthologue NG1427 is modulated by oxidation. | Molecular microbiology 20110201 |
| Reproduction impairment following paternal genotoxin exposure in brown trout (Salmo trutta) and Arctic charr (Salvelinus alpinus). | Aquatic toxicology (Amsterdam, Netherlands) 20110125 |
| TDP2/TTRAP is the major 5'-tyrosyl DNA phosphodiesterase activity in vertebrate cells and is critical for cellular resistance to topoisomerase II-induced DNA damage. | The Journal of biological chemistry 20110107 |
| The Budding Yeast 'Saccharomyces cerevisiae' as a Drug Discovery Tool to Identify Plant-Derived Natural Products with Anti-Proliferative Properties. | Evidence-based complementary and alternative medicine : eCAM 20110101 |
| Sensitivity of Bidens laevis L. to mutagenic compounds. Use of chromosomal aberrations as biomarkers of genotoxicity. | Environmental pollution (Barking, Essex : 1987) 20110101 |
| Toxicological evaluation of acyl glucuronides of nonsteroidal anti-inflammatory drugs using human embryonic kidney 293 cells stably expressing human UDP-glucuronosyltransferase and human hepatocytes. | Drug metabolism and disposition: the biological fate of chemicals 20110101 |
| Shortening of alkaline DNA unwinding time does not interfere with detecting DNA damage to mouse and human spermatozoa in the comet assay. | Asian journal of andrology 20110101 |
| Beryllium metal I. experimental results on acute oral toxicity, local skin and eye effects, and genotoxicity. | The Annals of occupational hygiene 20110101 |
| Rewiring makes the difference. | Molecular systems biology 20110101 |
| Ubiquitin-proteasome genes as targets for modulation of cisplatin sensitivity in fission yeast. | BMC genomics 20110101 |
| Identification of lysine 37 of histone H2B as a novel site of methylation. | PloS one 20110101 |
| Lysine residue 185 of Rad1 is a topological but not a functional counterpart of lysine residue 164 of PCNA. | PloS one 20110101 |
| Phosphorylation of the MBF repressor Yox1p by the DNA replication checkpoint keeps the G1/S cell-cycle transcriptional program active. | PloS one 20110101 |
| Interactions between the Nse3 and Nse4 components of the SMC5-6 complex identify evolutionarily conserved interactions between MAGE and EID Families. | PloS one 20110101 |
| In Vitro Anti-oxidant Effect of Vitamin E on Oxidative Stress Induced due to Pesticides in Rat Erythrocytes. | Toxicology international 20110101 |
| The base excision repair pathway is required for efficient lentivirus integration. | PloS one 20110101 |
| Pre-exposure to 50 Hz magnetic fields modifies menadione-induced genotoxic effects in human SH-SY5Y neuroblastoma cells. | PloS one 20110101 |
| A study protocol for the evaluation of occupational mutagenic/carcinogenic risks in subjects exposed to antineoplastic drugs: a multicentric project. | BMC public health 20110101 |
| A viable hypomorphic allele of the essential IMP3 gene reveals novel protein functions in Saccharomyces cerevisiae. | PloS one 20110101 |
| Recombination phenotypes of the NCI-60 collection of human cancer cells. | BMC molecular biology 20110101 |
| Requirement of replication checkpoint protein kinases Mec1/Rad53 for postreplication repair in yeast. | mBio 20110101 |
| Why eukaryotic cells use introns to enhance gene expression: splicing reduces transcription-associated mutagenesis by inhibiting topoisomerase I cutting activity. | Biology direct 20110101 |
| Real-time monitoring of cisplatin-induced cell death. | PloS one 20110101 |
| An active site aromatic triad in Escherichia coli DNA Pol IV coordinates cell survival and mutagenesis in different DNA damaging agents. | PloS one 20110101 |
| Gold-catalyzed regioselective oxidation of terminal allenes: formation of α-methanesulfonyloxy methyl ketones. | Beilstein journal of organic chemistry 20110101 |
| Rtt107 phosphorylation promotes localisation to DNA double-stranded breaks (DSBs) and recombinational repair between sister chromatids. | PloS one 20110101 |
| The essential functions of NEDD8 are mediated via distinct surface regions, and not by polyneddylation in Schizosaccharomyces pombe. | PloS one 20110101 |
| Fission yeast homologs of human XPC and CSB, rhp41 and rhp26, are involved in transcription-coupled repair of methyl methanesulfonate-induced DNA damage. | Genes & genetic systems 20110101 |
| DNA-PK-dependent RPA2 hyperphosphorylation facilitates DNA repair and suppresses sister chromatid exchange. | PloS one 20110101 |
| Evaluation of the genotoxic and antigenotoxic potential of Melissa officinalis in mice. | Genetics and molecular biology 20110101 |
| Ribosomal protein s3: a multifunctional target of attaching/effacing bacterial pathogens. | Frontiers in microbiology 20110101 |
| SWI/SNF and Asf1 independently promote derepression of the DNA damage response genes under conditions of replication stress. | PloS one 20110101 |
| Low level determinations of methyl methanesulfonate and ethyl methanesulfonate impurities in emtricitabine active pharmaceutical ingredient by LC/MS/MS using electrospray ionization. | Analytical chemistry insights 20110101 |
| Differential C3NET reveals disease networks of direct physical interactions. | BMC bioinformatics 20110101 |
| Tip60-mediated acetylation activates transcription independent apoptotic activity of Abl. | Molecular cancer 20110101 |
| Differences in sensitivity to DNA-damaging Agents between XRCC4- and Artemis-deficient human cells. | Journal of radiation research 20110101 |
| Methyl methanesulfonate. | Report on carcinogens : carcinogen profiles 20110101 |
| Lucanthone and its derivative hycanthone inhibit apurinic endonuclease-1 (APE1) by direct protein binding. | PloS one 20110101 |
| Functional characterization of the Saccharomyces cerevisiae protein Chl1 reveals the role of sister chromatid cohesion in the maintenance of spindle length during S-phase arrest. | BMC genetics 20110101 |
| Schizosaccharomyces pombe Ofd2 is a nuclear 2-oxoglutarate and iron dependent dioxygenase interacting with histones. | PloS one 20110101 |
| The role of Candida albicans homologous recombination factors Rad54 and Rdh54 in DNA damage sensitivity. | BMC microbiology 20110101 |
| Differential chromatin proteomics of the MMS-induced DNA damage response in yeast. | Proteome science 20110101 |
| Genomic phenotyping of the essential and non-essential yeast genome detects novel pathways for alkylation resistance. | BMC systems biology 20110101 |
| Liver cancer stem cells. | International journal of hepatology 20110101 |
| Differential genetic interactions between Sgs1, DNA-damage checkpoint components and DNA repair factors in the maintenance of chromosome stability. | Genome integrity 20110101 |
| Systems analysis of ATF3 in stress response and cancer reveals opposing effects on pro-apoptotic genes in p53 pathway. | PloS one 20110101 |
| Translesion DNA synthesis in the context of cancer research. | Cancer cell international 20110101 |
| A plant virus movement protein regulates the Gcn2p kinase in budding yeast. | PloS one 20110101 |
| The alkylation response protein AidB is localized at the new poles and constriction sites in Brucella abortus. | BMC microbiology 20110101 |
| Toxicity ranking and toxic mode of action evaluation of commonly used agricultural adjuvants on the basis of bacterial gene expression profiles. | PloS one 20110101 |
| Determination of Alkyl Methanesulfonates in Doxazosin Mesylate by Gas Chromatography-mass Spectrometer. | Indian journal of pharmaceutical sciences 20110101 |
| DNA electrophoretic migration patterns change after exposure of Jurkat cells to a single intense nanosecond electric pulse. | PloS one 20110101 |
| The effect of royal sun agaricus, Agaricus brasiliensis S. Wasser et al., extract on methyl methanesulfonate caused genotoxicity in Drosophila melanogaster. | International journal of medicinal mushrooms 20110101 |
| Preparation, characterization, and biological properties of β-glucans. | Journal of advanced pharmaceutical technology & research 20110101 |
| Checkpoint signaling, base excision repair, and PARP promote survival of colon cancer cells treated with 5-fluorodeoxyuridine but not 5-fluorouracil. | PloS one 20110101 |
| Estimates of DNA damage by the comet assay in the direct-developing frog Eleutherodactylus johnstonei (Anura, Eleutherodactylidae). | Genetics and molecular biology 20110101 |
| Caffeine abolishes the ultraviolet-induced REV3 translesion replication pathway in mouse cells. | International journal of molecular sciences 20110101 |
| Homologs of breast cancer genes in plants. | Frontiers in plant science 20110101 |
| Transgenerational adaptation to heavy metal salts in Arabidopsis. | Frontiers in plant science 20110101 |
| Angiotensin II, a Neuropeptide at the Frontier between Endocrinology and Neuroscience: Is There a Link between the Angiotensin II Type 2 Receptor and Alzheimer's Disease? | Frontiers in endocrinology 20110101 |
| Broad spectrum antimutagenic activity of antioxidant active fraction of punica granatum L. peel extracts. | Mutation research 20101221 |
| Miniaturized flow cytometric in vitro micronucleus assay represents an efficient tool for comprehensively characterizing genotoxicity dose-response relationships. | Mutation research 20101221 |
| Accumulation of true single strand breaks and AP sites in base excision repair deficient cells. | Mutation research 20101210 |
| Genetics. The DNA damage road map. | Science (New York, N.Y.) 20101203 |
| Rewiring of genetic networks in response to DNA damage. | Science (New York, N.Y.) 20101203 |
| Early life growth hormone treatment shortens longevity and decreases cellular stress resistance in long-lived mutant mice. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20101201 |
| Both base excision repair and O6-methylguanine-DNA methyltransferase protect against methylation-induced colon carcinogenesis. | Carcinogenesis 20101201 |
| Differential sensitivity of Arabidopsis siRNA biogenesis mutants to genotoxic stress. | Plant cell reports 20101201 |
| Prediction of the contact sensitizing potential of chemicals using analysis of gene expression changes in human THP-1 monocytes. | Toxicology letters 20101110 |
| Characterisation of Muta™Mouse λgt10-lacZ transgene: evidence for in vivo rearrangements. | Mutagenesis 20101101 |
| Ovate family protein 1 as a plant Ku70 interacting protein involving in DNA double-strand break repair. | Plant molecular biology 20101101 |
| DNA methylation and normal chromosome behavior in Neurospora depend on five components of a histone methyltransferase complex, DCDC. | PLoS genetics 20101101 |
| Activation of P53 in HepG2 cells as surrogate to detect mutagens and promutagens in vitro. | Toxicology letters 20101005 |
| Regulation of tolerance to DNA alkylating damage by Dot1 and Rad53 in Saccharomyces cerevisiae. | DNA repair 20101005 |
| The Werner's Syndrome protein collaborates with REV1 to promote replication fork progression on damaged DNA. | DNA repair 20101005 |
| Homologous recombination protects mammalian cells from replication-associated DNA double-strand breaks arising in response to methyl methanesulfonate. | DNA repair 20101005 |
| The Smc5/6 complex is required for dissolution of DNA-mediated sister chromatid linkages. | Nucleic acids research 20101001 |
| Carboxymethyl chitin-glucan (CM-CG) protects human HepG2 and HeLa cells against oxidative DNA lesions and stimulates DNA repair of lesions induced by alkylating agents. | Toxicology in vitro : an international journal published in association with BIBRA 20101001 |
| Simultaneous disruption of two DNA polymerases, Polη and Polζ, in Avian DT40 cells unmasks the role of Polη in cellular response to various DNA lesions. | PLoS genetics 20101001 |
| Subtle alterations in PCNA-partner interactions severely impair DNA replication and repair. | PLoS biology 20101001 |
| Linking Klotho, Nrf2, MAP kinases and aging. | Aging 20101001 |
| p300-mediated acetylation of histone H3 lysine 56 functions in DNA damage response in mammals. | The Journal of biological chemistry 20100910 |
| Methylated DNA causes a physical block to replication forks independently of damage signalling, O(6)-methylguanine or DNA single-strand breaks and results in DNA damage. | Journal of molecular biology 20100910 |
| Proficient repair in chromatin remodeling defective ino80 mutants of Saccharomyces cerevisiae highlights replication defects as the main contributor to DNA damage sensitivity. | DNA repair 20100904 |
| Novel small-molecule inhibitor of apurinic/apyrimidinic endonuclease 1 blocks proliferation and reduces viability of glioblastoma cells. | The Journal of pharmacology and experimental therapeutics 20100901 |
| Functional characterization of the PP2C phosphatase CaPtc2p in the human fungal pathogen Candida albicans. | Yeast (Chichester, England) 20100901 |
| The ASK1-Signalosome regulates p38 MAPK activity in response to levels of endogenous oxidative stress in the Klotho mouse models of aging. | Aging 20100901 |
| Critical functions of Rpa3/Ssb3 in S-phase DNA damage responses in fission yeast. | PLoS genetics 20100901 |
| The ability of the high-throughput comet assay to measure the sensitivity of five cell lines toward methyl methanesulfonate, hydrogen peroxide, and pentachlorophenol. | Mutation research 20100830 |
| Nicotine and methyl methane sulfonate in mini organ cultures of human parotid gland tissue. | Toxicology letters 20100816 |
| Alkylation DNA damage in combination with PARP inhibition results in formation of S-phase-dependent double-strand breaks. | DNA repair 20100805 |
| A single-strand specific lesion drives MMS-induced hyper-mutability at a double-strand break in yeast. | DNA repair 20100805 |
| Ferrochelatase is a conserved downstream target of the blue light-sensing White collar complex in fungi. | Microbiology (Reading, England) 20100801 |
| Tobacco mosaic virus infection results in an increase in recombination frequency and resistance to viral, bacterial, and fungal pathogens in the progeny of infected tobacco plants. | Plant physiology 20100801 |
| Deletion of a novel F-box protein, MUS-10, in Neurospora crassa leads to altered mitochondrial morphology, instability of mtDNA and senescence. | Genetics 20100801 |
| Genotoxicity assessment in the amphipod Gammarus fossarum by use of the alkaline Comet assay. | Mutation research 20100719 |
| Effect of the dibenzylbutyrolactone lignan (-)-hinokinin on doxorubicin and methyl methanesulfonate clastogenicity in V79 Chinese hamster lung fibroblasts. | Mutation research 20100719 |
| Whole cell-ELISA to measure the gammaH2AX response of six aneugens and eight DNA-damaging chemicals. | Mutation research 20100719 |
| Delineation of WRN helicase function with EXO1 in the replicational stress response. | DNA repair 20100701 |
| In vitro evaluation of baseline and induced DNA damage in human sperm exposed to benzo[a]pyrene or its metabolite benzo[a]pyrene-7,8-diol-9,10-epoxide, using the comet assay. | Mutagenesis 20100701 |
| Arabidopsis cockayne syndrome A-like proteins 1A and 1B form a complex with CULLIN4 and damage DNA binding protein 1A and regulate the response to UV irradiation. | The Plant cell 20100701 |
| The BRCT domain of PARP-1 is required for immunoglobulin gene conversion. | PLoS biology 20100701 |
| Overexpression of POLQ confers a poor prognosis in early breast cancer patients. | Oncotarget 20100701 |
| Mutagenicity of N-ethyl-N-nitrosourea, N-methyl-N-nitrosourea, methyl methanesulfonate and ethyl methanesulfonate in the developing Syrian hamster fetus. | Mutation research 20100617 |
| Genetic interactions between HNT3/Aprataxin and RAD27/FEN1 suggest parallel pathways for 5' end processing during base excision repair. | DNA repair 20100604 |
| Leaving group property of dimethyl sulfide. | The Journal of organic chemistry 20100604 |
| Antiproliferative, apoptotic and antimutagenic activity of isolated compounds from Polyalthia cerasoides seeds. | Phytomedicine : international journal of phytotherapy and phytopharmacology 20100601 |
| Antioxidant and antimutagenic activity of Carum copticum fruit extracts. | Toxicology in vitro : an international journal published in association with BIBRA 20100601 |
| Contribution of transcription-coupled DNA repair to MMS-induced mutagenesis in E. coli strains deficient in functional AlkB protein. | Mutation research 20100601 |
| Sensitization to radiation and alkylating agents by inhibitors of poly(ADP-ribose) polymerase is enhanced in cells deficient in DNA double-strand break repair. | Molecular cancer therapeutics 20100601 |
| Casein kinase 2-dependent phosphorylation of human Rad9 mediates the interaction between human Rad9-Hus1-Rad1 complex and TopBP1. | Genes to cells : devoted to molecular & cellular mechanisms 20100601 |
| The Dbf4 motif C zinc finger promotes DNA replication and mediates resistance to genotoxic stress. | Cell cycle (Georgetown, Tex.) 20100515 |
| Antigenotoxic potential of Gymnema montanum leaves on DNA damage in human peripheral blood lymphocytes and HL-60 cell line. | Environmental and molecular mutagenesis 20100501 |
| The role of reactive oxygen species in the induction of Ty1 retrotransposition in Saccharomyces cerevisiae. | Yeast (Chichester, England) 20100501 |
| Fission yeast Hsk1 (Cdc7) kinase is required after replication initiation for induced mutagenesis and proper response to DNA alkylation damage. | Genetics 20100501 |
| FACT prevents the accumulation of free histones evicted from transcribed chromatin and a subsequent cell cycle delay in G1. | PLoS genetics 20100501 |
| Automated analysis of DNA damage in the high-throughput version of the comet assay. | Mutation research 20100430 |
| Comet assay in murine bone-marrow cell line (FDC-P2). | Toxicology in vitro : an international journal published in association with BIBRA 20100401 |
| High content flow cytometric micronucleus scoring method is applicable to attachment cell lines. | Environmental and molecular mutagenesis 20100401 |
| Validation of an in vitro screening test for predicting the tumor promoting potential of chemicals based on gene expression. | Toxicology in vitro : an international journal published in association with BIBRA 20100401 |
| Parp1 activation in mouse embryonic fibroblasts promotes Pol beta-dependent cellular hypersensitivity to alkylation damage. | Mutation research 20100401 |
| A molecular beacon approach to detecting RAD52 expression in response to DNA damage in human cells. | Toxicology in vitro : an international journal published in association with BIBRA 20100301 |
| Lethal and mutagenic properties of MMS-generated DNA lesions in Escherichia coli cells deficient in BER and AlkB-directed DNA repair. | Mutagenesis 20100301 |
| Comparative transcriptome analysis reveals novel roles of the Ras and cyclic AMP signaling pathways in environmental stress response and antifungal drug sensitivity in Cryptococcus neoformans. | Eukaryotic cell 20100301 |
| Fumarase: a mitochondrial metabolic enzyme and a cytosolic/nuclear component of the DNA damage response. | PLoS biology 20100301 |
| Pharmacological and phytochemical study on a Sisymbrium officinale Scop. extract. | Journal of ethnopharmacology 20100217 |
| Abundance of ribosomal RNA gene copies maintains genome integrity. | Science (New York, N.Y.) 20100205 |
| Caenorhabditis elegans APN-1 plays a vital role in maintaining genome stability. | DNA repair 20100204 |
| Defects in DNA lesion bypass lead to spontaneous chromosomal rearrangements and increased cell death. | Eukaryotic cell 20100201 |
| Coupling cytotoxicity biomarkers with DNA damage assessment in TK6 human lymphoblast cells. | Mutation research 20100201 |
| Proteasome nuclear activity affects chromosome stability by controlling the turnover of Mms22, a protein important for DNA repair. | PLoS genetics 20100201 |
| [The Rdh54 protein role in regulation of DNA repair in yeast Saccharomyces cerevisiae]. | Genetika 20100201 |
| Effects of Saccharomyces cerevisiae mec1, tel1, and mre11 mutations on spontaneous and methylmethane sulfonate-induced genome instability. | Genes & genetic systems 20100201 |
| (4-Benzyl-2-oxo-1,3-oxazolidin-5-yl)methyl methane-sulfonate. | Acta crystallographica. Section E, Structure reports online 20100201 |
| Genotoxicity and antigenotoxicity evaluation of non-photoactivated hypericin. | Phytotherapy research : PTR 20100101 |
| Differential regulation of Apak by various DNA damage signals. | Molecular and cellular biochemistry 20100101 |
| Evaluation of the genotoxic and antigenotoxic potential of Baccharis dracunculifolia extract on V79 cells by the comet assay. | Journal of applied toxicology : JAT 20100101 |
| Adsorption behavior of ferritin and buffer components, buffer agents and salts, onto silane-coupled silicon substrate. | Colloids and surfaces. B, Biointerfaces 20100101 |
| Genotoxicity studies of organically grown broccoli (Brassica oleracea var. italica) and its interactions with urethane, methyl methanesulfonate and 4-nitroquinoline-1-oxide genotoxicity in the wing spot test of Drosophila melanogaster. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20100101 |
| Cytogenetic insights into DNA damage and repair of lesions induced by a monomethylated trivalent arsenical. | Mutation research 20100101 |
| Role of mitogen-activated protein kinase Sty1 in regulation of eukaryotic initiation factor 2alpha kinases in response to environmental stress in Schizosaccharomyces pombe. | Eukaryotic cell 20100101 |
| Altered gene expression and DNA damage in peripheral blood cells from Friedreich's ataxia patients: cellular model of pathology. | PLoS genetics 20100101 |
| Expression profiling of S. pombe acetyltransferase mutants identifies redundant pathways of gene regulation. | BMC genomics 20100101 |
| Collaborative action of Brca1 and CtIP in elimination of covalent modifications from double-strand breaks to facilitate subsequent break repair. | PLoS genetics 20100101 |
| 4beta-Hydroxywithanolide E from Physalis peruviana (golden berry) inhibits growth of human lung cancer cells through DNA damage, apoptosis and G2/M arrest. | BMC cancer 20100101 |
| Transgenerational adaptation of Arabidopsis to stress requires DNA methylation and the function of Dicer-like proteins. | PloS one 20100101 |
| Phenotypic effects of the circadian gene Cryptochrome 2 on cancer-related pathways. | BMC cancer 20100101 |
| Building and analyzing protein interactome networks by cross-species comparisons. | BMC systems biology 20100101 |
| Histone H3 serine 57 and lysine 56 interplay in transcription elongation and recovery from S-phase stress. | PloS one 20100101 |
| Environmental exposure of the mouse germ line: DNA adducts in spermatozoa and formation of de novo mutations during spermatogenesis. | PloS one 20100101 |
| The global dynamics of RNA stability orchestrates responses to cellular activation. | BMC biology 20100101 |
| The effect of a DNA damaging agent on embryonic cell cycles of the cnidarian Hydractinia echinata. | PloS one 20100101 |
| The SWR1 histone replacement complex causes genetic instability and genome-wide transcription misregulation in the absence of H2A.Z. | PloS one 20100101 |
| Plant DNA recombinases: a long way to go. | Journal of nucleic acids 20100101 |
| DNA polymerases beta and lambda mediate overlapping and independent roles in base excision repair in mouse embryonic fibroblasts. | PloS one 20100101 |
| Genetic and biochemical characterization of human AP endonuclease 1 mutants deficient in nucleotide incision repair activity. | PloS one 20100101 |
| Identification of response-modulated genetic interactions by sensitivity-based epistatic analysis. | BMC genomics 20100101 |
| The unfolded protein response is not necessary for the G1/S transition, but it is required for chromosome maintenance in Saccharomyces cerevisiae. | PloS one 20100101 |
| Characterisation of the SUMO-like domains of Schizosaccharomyces pombe Rad60. | PloS one 20100101 |
| The Roles of UmuD in Regulating Mutagenesis. | Journal of nucleic acids 20100101 |
| Mus308 processes oxygen and nitrogen ethylation DNA damage in germ cells of Drosophila. | Journal of nucleic acids 20100101 |
| Effect of n3-methyladenine and an isosteric stable analogue on DNA polymerization. | Journal of nucleic acids 20100101 |
| Early Steps in the DNA Base Excision Repair Pathway of a Fission Yeast Schizosaccharomyces pombe. | Journal of nucleic acids 20100101 |
| Comparison of mitotic cell death by chromosome fragmentation to premature chromosome condensation. | Molecular cytogenetics 20100101 |
| Checkpoint-dependent and -independent roles of Swi3 in replication fork recovery and sister chromatid cohesion in fission yeast. | PloS one 20100101 |
| Overview of DNA Repair in Trypanosoma cruzi, Trypanosoma brucei, and Leishmania major. | Journal of nucleic acids 20100101 |
| Is the comet assay a sensitive procedure for detecting genotoxicity? | Journal of nucleic acids 20100101 |
| The roles of the Saccharomyces cerevisiae RecQ helicase SGS1 in meiotic genome surveillance. | PloS one 20100101 |
| PI 3 kinase related kinases-independent proteolysis of BRCA1 regulates Rad51 recruitment during genotoxic stress in human cells. | PloS one 20100101 |
| DNA damage induced by alkylating agents and repair pathways. | Journal of nucleic acids 20100101 |
| Rrd1 isomerizes RNA polymerase II in response to rapamycin. | BMC molecular biology 20100101 |
| Antigenotoxic effect of Chamomilla recutita (L.) Rauschert essential oil in mouse spermatogonial cells, and determination of its antioxidant capacity in vitro. | International journal of molecular sciences 20100101 |
| Genetic analysis of DNA repair in the hyperthermophilic archaeon, Thermococcus kodakaraensis. | Genes & genetic systems 20100101 |
| Mammalian target of rapamycin: hitting the bull's-eye for neurological disorders. | Oxidative medicine and cellular longevity 20100101 |
| Determination of the antimutagenicity of an aqueous extract of Rhizophora mangle L. (Rhizophoraceae), using in vivo and in vitro test systems. | Genetics and molecular biology 20100101 |
| Protective effect of Hemidesmus indicus R.Br. root extract against cisplatin-induced cytogenetic damage in mouse bone marrow cells. | Genetics and molecular biology 20100101 |
| Effect of annatto on micronuclei induction by direct and indirect mutagens in HepG2 cells. | Environmental and molecular mutagenesis 20091201 |
| Mutagenic potency of MMS-induced 1meA/3meC lesions in E. coli. | Environmental and molecular mutagenesis 20091201 |
| Cells deficient in PARP-1 show an accelerated accumulation of DNA single strand breaks, but not AP sites, over the PARP-1-proficient cells exposed to MMS. | Mutation research 20091201 |
| Replication protein A (RPA1a) is required for meiotic and somatic DNA repair but is dispensable for DNA replication and homologous recombination in rice. | Plant physiology 20091201 |
| Distinct mechanisms are utilized to induce stress sensor gadd45b by different stress stimuli. | Journal of cellular biochemistry 20091201 |
| A metabolomic and multivariate statistical process to assess the effects of genotoxins in Saccharomyces cerevisiae. | Molecular bioSystems 20091201 |
| EMS in Viracept--initial ('traditional') assessment of risk to patients based on linear dose response relations. | Toxicology letters 20091112 |
| PARP inhibition during alkylation-induced genotoxic stress signals a cell cycle checkpoint response mediated by ATM. | DNA repair 20091102 |
| Micronucleus and chromosome aberrations induced in onion (Allium cepa) by a petroleum refinery effluent and by river water that receives this effluent. | Ecotoxicology and environmental safety 20091101 |
| Arabidopsis actin-related protein ARP5 in multicellular development and DNA repair. | Developmental biology 20091101 |
| Involvement of a chromatin remodeling complex in damage tolerance during DNA replication. | Nature structural & molecular biology 20091101 |
| Global analysis of mutual interaction surfaces of nucleosomes with comprehensive point mutants. | Genes to cells : devoted to molecular & cellular mechanisms 20091101 |
| Clock gene mutation modulates the cellular sensitivity to genotoxic stress through altering the expression of N-methylpurine DNA glycosylase gene. | Biochemical pharmacology 20091015 |
| Optimization of bacterial whole cell bioreporters for toxicity assay of environmental samples. | Environmental science & technology 20091015 |
| Chromatographic method for quick estimation of DNA interaction potency of environmental pollutants. | Environmental toxicology and chemistry 20091001 |
| The elongator complex interacts with PCNA and modulates transcriptional silencing and sensitivity to DNA damage agents. | PLoS genetics 20091001 |
| Dermal fibroblasts from long-lived Ames dwarf mice maintain their in vivo resistance to mitochondrial generated reactive oxygen species (ROS). | Aging 20090901 |
| Linking genotoxic responses with cytotoxic and behavioural or physiological consequences: differential sensitivity of echinoderms (Asterias rubens) and marine molluscs (Mytilus edulis). | Aquatic toxicology (Amsterdam, Netherlands) 20090813 |
| SnCl(2)-induced DNA damage and repair inhibition of MMS-caused lesions in V79 Chinese hamster fibroblasts. | Archives of toxicology 20090801 |
| Statistical model to estimate a threshold dose and its confidence limits for the analysis of sublinear dose-response relationships, exemplified for mutagenicity data. | Mutation research 20090801 |
| Antimutagenic activity of a secoisopimarane diterpenoid from Salvia cinnabarina M. Martens et Galeotti in the bacterial reverse mutation assay. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20090801 |
| Transcriptional gene silencing mediated by a plastid inner envelope phosphoenolpyruvate/phosphate translocator CUE1 in Arabidopsis. | Plant physiology 20090801 |
| Biological significance of DNA adducts: comparison of increments over background for various biomarkers of genotoxicity in L5178Y tk(+/-) mouse lymphoma cells treated with hydrogen peroxide and cumene hydroperoxide. | Mutation research 20090801 |
| Dose-response and operational thresholds/NOAELs for in vitro mutagenic effects from DNA-reactive mutagens, MMS and MNU. | Mutation research 20090801 |
| Conformational and vibrational analysis of methyl methanesulfonate, CH3SO2OCH3. | The journal of physical chemistry. A 20090723 |
| Kinetics of an extracellular exo-inulinase production from a 5-flourocytosine resistant mutant of Geotrichum candidum using two-factorial design. | Bioresource technology 20090701 |
| Inefficient double-strand DNA break repair is associated with increased fasciation in Arabidopsis BRCA2 mutants. | Journal of experimental botany 20090701 |
| Mre11-Rad50 promotes rapid repair of DNA damage in the polyploid archaeon Haloferax volcanii by restraining homologous recombination. | PLoS genetics 20090701 |
| FEN1 is overexpressed in testis, lung and brain tumors. | Anticancer research 20090701 |
| Predicting functionality of protein-DNA interactions by integrating diverse evidence. | Bioinformatics (Oxford, England) 20090615 |
| Accumulation of sumoylated Rad52 in checkpoint mutants perturbed in DNA replication. | DNA repair 20090604 |
| Synergistic decrease of DNA single-strand break repair rates in mouse neural cells lacking both Tdp1 and aprataxin. | DNA repair 20090604 |
| Metabolic response to MMS-mediated DNA damage in Saccharomyces cerevisiae is dependent on the glucose concentration in the medium. | FEMS yeast research 20090601 |
| A phylogenetically conserved DNA damage response resets the circadian clock. | Journal of biological rhythms 20090601 |
| A network of conserved damage survival pathways revealed by a genomic RNAi screen. | PLoS genetics 20090601 |
| Telomere recombination accelerates cellular aging in Saccharomyces cerevisiae. | PLoS genetics 20090601 |
| Analysis of 7,8-dihydro-8-oxo-2'-deoxyguanosine in cellular DNA during oxidative stress. | Chemical research in toxicology 20090518 |
| Characterization in vitro and in vivo of the DNA helicase encoded by Deinococcus radiodurans locus DR1572. | DNA repair 20090501 |
| The role of novel genes rrp1(+) and rrp2(+) in the repair of DNA damage in Schizosaccharomyces pombe. | DNA repair 20090501 |
| Requirement of the Saccharomyces cerevisiae APN1 gene for the repair of mitochondrial DNA alkylation damage. | Environmental and molecular mutagenesis 20090501 |
| Determination of genotoxic effects of copper sulphate and cobalt chloride in Allium cepa root cells by chromosome aberration and comet assays. | Chemosphere 20090501 |
| Tetrahymena meiotic nuclear reorganization is induced by a checkpoint kinase-dependent response to DNA damage. | Molecular biology of the cell 20090501 |
| Performance of the comet assay in a high-throughput version. | Mutation research 20090430 |
| Differential regulation of homologous recombination at DNA breaks and replication forks by the Mrc1 branch of the S-phase checkpoint. | The EMBO journal 20090422 |
| Maximal extraction of biological information from genetic interaction data. | PLoS computational biology 20090401 |
| Base excision by thymine DNA glycosylase mediates DNA-directed cytotoxicity of 5-fluorouracil. | PLoS biology 20090401 |
| Enhancement of methyl methanesulfonate-induced base excision repair in the presence of selenomethionine on p53-dependent pathway. | Journal of medicinal food 20090401 |
| DNA damage, signalling and repair after exposure of cells to the sulphur mustard analogue 2-chloroethyl ethyl sulphide. | Toxicology 20090329 |
| Hydroxyurea sensitivity reveals a role for ISC1 in the regulation of G2/M. | The Journal of biological chemistry 20090327 |
| Chelator-facilitated chemical modification of IMP-1 metallo-beta-lactamase and its consequences on metal binding. | Biochemical and biophysical research communications 20090327 |
| Cooperativity of Mus81.Mms4 with Rad54 in the resolution of recombination and replication intermediates. | The Journal of biological chemistry 20090320 |
| Intralaboratory and interlaboratory evaluation of the EpiDerm 3D human reconstructed skin micronucleus (RSMN) assay. | Mutation research 20090317 |
| Phosphorylation of Ewing's sarcoma protein (EWS) and EWS-Fli1 in response to DNA damage. | The Biochemical journal 20090315 |
| Differential roles of proteins involved in migration of Holliday junctions on recombination and tolerance to DNA damaging agents in Rhizobium etli. | Gene 20090301 |
| The DNA repair protein NBS1 influences the base excision repair pathway. | Carcinogenesis 20090301 |
| Ubiquitination and deubiquitination of PCNA in response to stalling of the replication fork. | Cell cycle (Georgetown, Tex.) 20090301 |
| A novel protein, MAPO1, that functions in apoptosis triggered by O6-methylguanine mispair in DNA. | Oncogene 20090226 |
| Introduction and characterization of a polymerase-dead point mutation into the POLK gene in vertebrates. | FEBS letters 20090218 |
| Detection of excision repaired DNA damage in the comet assay by using Ara-C and hydroxyurea in three different cell types. | Cell biology and toxicology 20090201 |
| Inhibition of DNA double-strand break repair by the Ku heterodimer in mrx mutants of Saccharomyces cerevisiae. | DNA repair 20090201 |
| Functional characterization of the RAD51D E233G genetic variant. | Pharmacogenetics and genomics 20090201 |
| Genome-wide analysis of factors affecting transcription elongation and DNA repair: a new role for PAF and Ccr4-not in transcription-coupled repair. | PLoS genetics 20090201 |
| Epigenetic regulation, somatic homologous recombination, and abscisic acid signaling are influenced by DNA polymerase epsilon mutation in Arabidopsis. | The Plant cell 20090201 |
| Reproductive consequences of paternal genotoxin exposure in marine invertebrates. | Environmental science & technology 20090201 |
| Investigation on the protective effect of α-mannan against the DNA damage induced by aflatoxin B₁in mouse hepatocytes. | International journal of molecular sciences 20090201 |
| HBx protein modulates PI3K/Akt pathway to overcome genotoxic stress-induced destabilization of cyclin D1 and arrest of cell cycle. | Indian journal of biochemistry & biophysics 20090201 |
| Adherens junction-dependent PI3K/Akt activation induces resistance to genotoxin-induced cell death in differentiated intestinal epithelial cells. | Biochemical and biophysical research communications 20090123 |
| Distinct requirements for the Rad32(Mre11) nuclease and Ctp1(CtIP) in the removal of covalently bound topoisomerase I and II from DNA. | Molecular cell 20090116 |
| Gene targeting in a nonhomologous end joining deficient Hypocrea jecorina. | Journal of biotechnology 20090115 |
| Systems based mapping demonstrates that recovery from alkylation damage requires DNA repair, RNA processing, and translation associated networks. | Genomics 20090101 |
| Automated image analysis of cytokinesis-blocked micronuclei: an adapted protocol and a validated scoring procedure for biomonitoring. | Mutagenesis 20090101 |
| Drosophila hold'em is required for a subset of meiotic crossovers and interacts with the dna repair endonuclease complex subunits MEI-9 and ERCC1. | Genetics 20090101 |
| Antimutagenic effect of sage tea in the wing spot test of Drosophila melanogaster. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20090101 |
| Evaluation of cytotoxic and cytostatic effects in Saccharomyces cerevisiae by poissoner quantitative drop test. | Basic & clinical pharmacology & toxicology 20090101 |
| The Elg1-RFC clamp-loading complex performs a role in sister chromatid cohesion. | PloS one 20090101 |
| Three new structures of left-handed RADA helical filaments: structural flexibility of N-terminal domain is critical for recombinase activity. | PloS one 20090101 |
| The N-terminal domain of Escherichia coli RecA have multiple functions in promoting homologous recombination. | Journal of biomedical science 20090101 |
| Serpin genes AtSRP2 and AtSRP3 are required for normal growth sensitivity to a DNA alkylating agent in Arabidopsis. | BMC plant biology 20090101 |
| The ELG1 clamp loader plays a role in sister chromatid cohesion. | PloS one 20090101 |
| Attaching and effacing Escherichia coli downregulate DNA mismatch repair protein in vitro and are associated with colorectal adenocarcinomas in humans. | PloS one 20090101 |
| Identification and characterization of inhibitors of human apurinic/apyrimidinic endonuclease APE1. | PloS one 20090101 |
| Comparative genome-wide screening identifies a conserved doxorubicin repair network that is diploid specific in Saccharomyces cerevisiae. | PloS one 20090101 |
| Genotoxicity evaluation of chlorpyrifos to amphibian Chinese toad (Amphibian: Anura) by Comet assay and Micronucleus test. | Mutation research 20090101 |
| Adaptive response to DNA-damaging agents in natural Saccharomyces cerevisiae populations from 'Evolution Canyon', Mt. Carmel, Israel. | PloS one 20090101 |
| Screening of antimutagenicity via antioxidant activity in different extracts from the flowers of Phlomis crinita Cav. ssp mauritanica munby from the center of Tunisia. | Drug and chemical toxicology 20090101 |
| DNA ligase 1 deficient plants display severe growth defects and delayed repair of both DNA single and double strand breaks. | BMC plant biology 20090101 |
| dRecQ4 is required for DNA synthesis and essential for cell proliferation in Drosophila. | PloS one 20090101 |
| Histological analysis of low dose NMU effects in the rat mammary gland. | BMC cancer 20090101 |
| SUMO chain formation is required for response to replication arrest in S. pombe. | PloS one 20090101 |
| Transcriptome and proteome analyses of adaptive responses to methyl methanesulfonate in Escherichia coli K-12 and ada mutant strains. | BMC microbiology 20090101 |
| The role of specific checkpoint-induced S-phase transcripts in resistance to replicative stress. | PloS one 20090101 |
| Graph ranking for exploratory gene data analysis. | BMC bioinformatics 20090101 |
| DNA damage induced by cis- and carboplatin as indicator for in vitro sensitivity of ovarian carcinoma cells. | BMC cancer 20090101 |
| The pol3-t hyperrecombination phenotype and DNA damage-induced recombination in Saccharomyces cerevisiae is RAD50 dependent. | Journal of biomedicine & biotechnology 20090101 |
| Genomic instability and DNA damage responses in progeria arising from defective maturation of prelamin A. | Aging 20090101 |
| [Streptomyces globisporus 1912 mutants highly sensitive to ultraviolet radiation, their antibiotic activity and reparation ability]. | Mikrobiolohichnyi zhurnal (Kiev, Ukraine : 1993) 20090101 |
| Recruitment of Rad51 and Rad52 to short telomeres triggers a Mec1-mediated hypersensitivity to double-stranded DNA breaks in senescent budding yeast. | PloS one 20090101 |
| Sirtuins at the breaking point: SIRT6 in DNA repair. | Aging 20090101 |
| Application of the comet assay in erythrocytes of Oreochromis niloticus (Pisces): A methodological comparison. | Genetics and molecular biology 20090101 |
| Cytotoxic and genotoxic effects of Br-containing oxaphosphole on Allium cepa L. root tip cells and mouse bone marrow cells. | Genetics and molecular biology 20090101 |
| Saw palmetto extract induces nuclear heterogeneity in mice. | Environmental toxicology and pharmacology 20090101 |
| Regulated proteolysis of DNA polymerase eta during the DNA-damage response in C. elegans. | Molecular cell 20081226 |
| Micronucleus induction in V79 cells by the anabolic doping steroids desoxymethyltestosterone (madol) and 19-norandrostenedione. | Toxicology letters 20081215 |
| No-observed effect levels are associated with up-regulation of MGMT following MMS exposure. | Mutation research 20081215 |
| The G1-S checkpoint in fission yeast is not a general DNA damage checkpoint. | Journal of cell science 20081215 |
| Tests for genotoxicity and mutagenicity of furan and its metabolite cis-2-butene-1,4-dial in L5178Y tk+/- mouse lymphoma cells. | Mutation research 20081208 |
| The expression level of the chromatin-associated HMGB1 protein influences growth, stress tolerance, and transcriptome in Arabidopsis. | Journal of molecular biology 20081205 |
| Genotoxicity screening of the river Rasina in Serbia using the Allium anaphase-telophase test. | Environmental monitoring and assessment 20081201 |
| Influence of DNA repair gene polymorphisms on the initial repair of MMS-induced DNA damage in human lymphocytes as measured by the alkaline comet assay. | Environmental and molecular mutagenesis 20081201 |
| Novel methylotrophic bacteria isolated from the River Thames (London, UK). | Environmental microbiology 20081201 |
| Deletion of MAG1 and MRE11 enhances the sensitivity of the Saccharomyces cerevisiae HUG1P-GFP promoter-reporter construct to genotoxicity. | Biosensors & bioelectronics 20081201 |
| Protective effect of Crocus sativus stigma extract and crocin (trans-crocin 4) on methyl methanesulfonate-induced DNA damage in mice organs. | DNA and cell biology 20081201 |
| Kinetics of gamma-H2AX focus formation upon treatment of cells with UV light and alkylating agents. | Environmental and molecular mutagenesis 20081201 |
| An in vivo comet assay of multiple organs (liver, kidney and bone marrow) in mice treated with methyl methanesulfonate and acetaminophen accompanied by hematology and/or blood chemistry. | The Journal of toxicological sciences 20081201 |
| Embryonic mortality and intrauterine growth retardation (IUGR) associated with placental alterations in pregnant rats treated with methyl methanesulfonate (MMS) at the peri-implantation stage. | The Journal of toxicological sciences 20081201 |
| Spt2p defines a new transcription-dependent gross chromosomal rearrangement pathway. | PLoS genetics 20081201 |
| News from Arabidopsis on the meiotic roles of Blap75/Rmi1 and Top3alpha. | PLoS genetics 20081201 |
| Localization of Smc5/6 to centromeres and telomeres requires heterochromatin and SUMO, respectively. | The EMBO journal 20081119 |
| Expression of death receptor 4 induces caspase-independent cell death in MMS-treated yeast. | Biochemical and biophysical research communications 20081114 |
| Human glyceraldehyde-3-phosphate dehydrogenase plays a direct role in reactivating oxidized forms of the DNA repair enzyme APE1. | The Journal of biological chemistry 20081107 |
| A molecular bar-coded DNA repair resource for pooled toxicogenomic screens. | DNA repair 20081101 |
| Hypermutability of damaged single-strand DNA formed at double-strand breaks and uncapped telomeres in yeast Saccharomyces cerevisiae. | PLoS genetics 20081101 |
| Chemical-genetic profiling of imidazo[1,2-a]pyridines and -pyrimidines reveals target pathways conserved between yeast and human cells. | PLoS genetics 20081101 |
| Interplay between Np95 and Eme1 in the DNA damage response. | Biochemical and biophysical research communications 20081024 |
| Regulation of proliferating cell nuclear antigen ubiquitination in mammalian cells. | Proceedings of the National Academy of Sciences of the United States of America 20081021 |
| Identification and characterization of novel SNPs in CHEK2 in Ashkenazi Jewish men with prostate cancer. | Cancer letters 20081018 |
| DNA damage-induced reactive oxygen species (ROS) stress response in Saccharomyces cerevisiae. | Free radical biology & medicine 20081015 |
| BLAP18/RMI2, a novel OB-fold-containing protein, is an essential component of the Bloom helicase-double Holliday junction dissolvasome. | Genes & development 20081015 |
| The FANCM ortholog Fml1 promotes recombination at stalled replication forks and limits crossing over during DNA double-strand break repair. | Molecular cell 20081010 |
| Multiple pathways cooperate to facilitate DNA replication fork progression through alkylated DNA. | DNA repair 20081001 |
| Substrate binding pocket residues of human alkyladenine-DNA glycosylase critical for methylating agent survival. | DNA repair 20081001 |
| Analysis of Saccharomyces cerevisiae histone H3 mutants reveals the role of the alphaN helix in nucleosome function. | Biochemical and biophysical research communications 20080926 |
| Histone H2AX is a critical factor for cellular protection against DNA alkylating agents. | Oncogene 20080925 |
| SUMO modification of PCNA is controlled by DNA. | The EMBO journal 20080917 |
| Constitutive SOS expression and damage-inducible AddAB-mediated recombinational repair systems for Coxiella burnetii as potential adaptations for survival within macrophages. | Molecular microbiology 20080901 |
| uvsF RFC1, the large subunit of replication factor C in Aspergillus nidulans, is essential for DNA replication, functions in UV repair and is upregulated in response to MMS-induced DNA damage. | Fungal genetics and biology : FG & B 20080901 |
| Antimutagenic activity of methanolic extracts of four ayurvedic medicinal plants. | Indian journal of experimental biology 20080901 |
| Model of human aging: recent findings on Werner's and Hutchinson-Gilford progeria syndromes. | Clinical interventions in aging 20080901 |
| Transcription increases methylmethane sulfonate-induced mutations in alkB strains of Escherichia coli. | DNA repair 20080802 |
| Characterization of the role of a trimeric protein phosphatase complex in recovery from cisplatin-induced versus noncrosslinking DNA damage. | The FEBS journal 20080801 |
| Inference of protein complex activities from chemical-genetic profile and its applications: predicting drug-target pathways. | PLoS computational biology 20080801 |
| [Role of hREV3 in cell cycle and proliferation]. | Yi chuan = Hereditas 20080801 |
| Rad53 regulates replication fork restart after DNA damage in Saccharomyces cerevisiae. | Genes & development 20080715 |
| Planarian neoblast micronucleus assay for evaluating genotoxicity. | Chemosphere 20080701 |
| Role of Dot1 in the response to alkylating DNA damage in Saccharomyces cerevisiae: regulation of DNA damage tolerance by the error-prone polymerases Polzeta/Rev1. | Genetics 20080701 |
| A potential link between alternative splicing of the NBS1 gene and DNA damage/environmental stress. | Radiation research 20080701 |
| Separate roles for the DNA damage checkpoint protein kinases in stabilizing DNA replication forks. | Genes & development 20080701 |
| Identification and dissection of a complex DNA repair sensitivity phenotype in Baker's yeast. | PLoS genetics 20080701 |
| Genotoxic damage in polychaetes: a study of species and cell-type sensitivities. | Mutation research 20080630 |
| DNA damage response protein ASCIZ links base excision repair with immunoglobulin gene conversion. | Biochemical and biophysical research communications 20080627 |
| Cdc6 determines utilization of p21(WAF1/CIP1)-dependent damage checkpoint in S phase cells. | The Journal of biological chemistry 20080627 |
| Long-term functional stability of human HepaRG hepatocytes and use for chronic toxicity and genotoxicity studies. | Drug metabolism and disposition: the biological fate of chemicals 20080601 |
| The methyl methanesulfonate induced S-phase delay in XRCC1-deficient cells requires ATM and ATR. | DNA repair 20080601 |
| Rad52 sumoylation and its involvement in the efficient induction of homologous recombination. | DNA repair 20080601 |
| The anaphase-promoting complex/cyclosome controls repair and recombination by ubiquitylating Rhp54 in fission yeast. | Molecular and cellular biology 20080601 |
| Trypanosoma brucei BRCA2 acts in antigenic variation and has undergone a recent expansion in BRC repeat number that is important during homologous recombination. | Molecular microbiology 20080601 |
| Antimutagenic and mutagenic activities of some terpenes in the bacterial reverse mutation assay. | Mutation research 20080531 |
| Budding yeast Mms22 and Mms1 regulate homologous recombination induced by replisome blockage. | DNA repair 20080503 |
| A yeast-based genetic screening to identify human proteins that increase homologous recombination. | FEMS yeast research 20080501 |
| Evaluation of DNA damage in Chinese toad (Bufo bufo gargarizans) after in vivo exposure to sublethal concentrations of four herbicides using the comet assay. | Ecotoxicology (London, England) 20080501 |
| Decreased expression of methyl methansulfonate and ultraviolet-sensitive gene clone 81 (Mus81) is correlated with a poor prognosis in patients with hepatocellular carcinoma. | Cancer 20080501 |
| Schizosaccharomyces pombe Hst4 functions in DNA damage response by regulating histone H3 K56 acetylation. | Eukaryotic cell 20080501 |
| Angiotensin II type 2 receptor deletion enhances vascular senescence by methyl methanesulfonate sensitive 2 inhibition. | Hypertension (Dallas, Tex. : 1979) 20080501 |
| Quantitation of methylated hemoglobin adducts in a signature peptide from rat blood by liquid chromatography/negative electrospray ionization tandem mass spectrometry. | Rapid communications in mass spectrometry : RCM 20080501 |
| ATP-dependent chromatin remodeling shapes the DNA replication landscape. | Nature structural & molecular biology 20080501 |
| Completely automated short-term genotoxicity testing for the assessment of chemicals and characterisation of contaminated soils and waste waters. | Environmental science and pollution research international 20080501 |
| Binding of MutS protein to oligonucleotides containing a methylated or an ethylated guanine residue, and correlation with mutation frequency. | Mutation research 20080402 |
| Unique and overlapping functions of the Exo1, Mre11 and Pso2 nucleases in DNA repair. | DNA repair 20080402 |
| A homolog of ScRAD5 is involved in DNA repair and homologous recombination in Arabidopsis. | Plant physiology 20080401 |
| Location-specific functions of the two forkhead-associated domains in Rad53 checkpoint kinase signaling. | Biochemistry 20080325 |
| The RecQ helicase WRN is required for normal replication fork progression after DNA damage or replication fork arrest. | Cell cycle (Georgetown, Tex.) 20080315 |
| Activation of ubiquitin-dependent DNA damage bypass is mediated by replication protein a. | Molecular cell 20080314 |
| Development and validation of GC-MS method for the determination of methyl methanesulfonate and ethyl methanesulfonate in imatinib mesylate. | Journal of pharmaceutical and biomedical analysis 20080313 |
| Inhibition of translation and modification of translation factors during apoptosis induced by the DNA-damaging agent MMS in sea urchin embryos. | Experimental cell research 20080310 |
| In vitro antioxidant, antimutagenic and genoprotective activity of Rosa roxburghii fruit extract. | Phytotherapy research : PTR 20080301 |
| Role of homologous recombination in trabectedin-induced DNA damage. | European journal of cancer (Oxford, England : 1990) 20080301 |
| The Medicinal Mushroom Agaricus blazei Murrill: Review of Literature and Pharmaco-Toxicological Problems. | Evidence-based complementary and alternative medicine : eCAM 20080301 |
| Cells from long-lived mutant mice exhibit enhanced repair of ultraviolet lesions. | The journals of gerontology. Series A, Biological sciences and medical sciences 20080301 |
| Fibroblasts from naked mole-rats are resistant to multiple forms of cell injury, but sensitive to peroxide, ultraviolet light, and endoplasmic reticulum stress. | The journals of gerontology. Series A, Biological sciences and medical sciences 20080301 |
| Using exonuclease III to enhance electrochemical detection of natural DNA damage in layered films. | Biosensors & bioelectronics 20080227 |
| The Neurospora crassa UVS-3 epistasis group encodes homologues of the ATR/ATRIP checkpoint control system. | DNA repair 20080201 |
| Species-specific inhibition of Giardia lamblia triosephosphate isomerase by localized perturbation of the homodimer. | Molecular and biochemical parasitology 20080201 |
| Analyses of functional interaction between RECQL1, RECQL5, and BLM which physically interact with DNA topoisomerase IIIalpha. | Biochimica et biophysica acta 20080201 |
| Identification of the proteins, including MAGEG1, that make up the human SMC5-6 protein complex. | Molecular and cellular biology 20080201 |
| Functional interactions between Sae2 and the Mre11 complex. | Genetics 20080201 |
| Drosophila brca2 is required for mitotic and meiotic DNA repair and efficient activation of the meiotic recombination checkpoint. | PLoS genetics 20080201 |
| Increased transmission of mutations by low-condition females: evidence for condition-dependent DNA repair. | PLoS biology 20080201 |
| Genetic analysis of the Neurospora crassa RAD14 homolog mus-43 and the RAD10 homolog mus-44 reveals that they belong to the mus-38 pathway of two nucleotide excision repair systems. | Genes & genetic systems 20080201 |
| Vertebrate WRNIP1 and BLM are required for efficient maintenance of genome stability. | Genes & genetic systems 20080201 |
| DNA damage activates the SAC in an ATM/ATR-dependent manner, independently of the kinetochore. | PLoS genetics 20080201 |
| Extremely low frequency (ELF) magnetic fields enhance chemically induced formation of apurinic/apyrimidinic (AP) sites in A172 cells. | International journal of radiation biology 20080101 |
| Deletion of the cpku80 gene in the chestnut blight fungus, Cryphonectria parasitica, enhances gene disruption efficiency. | Current genetics 20080101 |
| Arabidopsis UEV1D promotes Lysine-63-linked polyubiquitination and is involved in DNA damage response. | The Plant cell 20080101 |
| Yeast screens identify the RNA polymerase II CTD and SPT5 as relevant targets of BRCA1 interaction. | PloS one 20080101 |
| Essential and distinct roles of the F-box and helicase domains of Fbh1 in DNA damage repair. | BMC molecular biology 20080101 |
| Membrane transporters and protein traffic networks differentially affecting metal tolerance: a genomic phenotyping study in yeast. | Genome biology 20080101 |
| Acetylation regulates WRN catalytic activities and affects base excision DNA repair. | PloS one 20080101 |
| Structural insights on the pamoic acid and the 8 kDa domain of DNA polymerase beta complex: towards the design of higher-affinity inhibitors. | BMC structural biology 20080101 |
| Homeostatic imbalance between apoptosis and cell renewal in the liver of premature aging Xpd mice. | PloS one 20080101 |
| The effects of protein interactions, gene essentiality and regulatory regions on expression variation. | BMC systems biology 20080101 |
| Structure and properties of transcriptional networks driving selenite stress response in yeasts. | BMC genomics 20080101 |
| Selective inhibition of yeast regulons by daunorubicin: a transcriptome-wide analysis. | BMC genomics 20080101 |
| [Rpn4p is a positive and negative transcriptional regulator of the ubiquitin-proteasome system]. | Molekuliarnaia biologiia 20080101 |
| Chemogenetic fingerprinting by analysis of cellular growth dynamics. | BMC chemical biology 20080101 |
| The essential function of Swc4p - a protein shared by two chromatin-modifying complexes of the yeast Saccharomyces cerevisiae - resides within its N-terminal part. | Acta biochimica Polonica 20080101 |
| Gadd45 in stress signaling. | Journal of molecular signaling 20080101 |
| Inducible SOS response system of DNA repair and mutagenesis in Escherichia coli. | International journal of biological sciences 20080101 |
| A genome wide analysis of the response to uncapped telomeres in budding yeast reveals a novel role for the NAD+ biosynthetic gene BNA2 in chromosome end protection. | Genome biology 20080101 |
| Transient transcriptional responses to stress are generated by opposing effects of mRNA production and degradation. | Molecular systems biology 20080101 |
| Effect of Ku80 deficiency on mutation frequencies and spectra at a LacZ reporter locus in mouse tissues and cells. | PloS one 20080101 |
| Anc1, a protein associated with multiple transcription complexes, is involved in postreplication repair pathway in S. cerevisiae. | PloS one 20080101 |
| Rapid telomere motions in live human cells analyzed by highly time-resolved microscopy. | Epigenetics & chromatin 20080101 |
| Drug design with Cdc7 kinase: a potential novel cancer therapy target. | Drug design, development and therapy 20080101 |
| Chemical DNA damage activates p21 WAF1/CIP1-dependent intra-S checkpoint. | FEBS letters 20071222 |
| Measurement of the heme affinity for yeast dap1p, and its importance in cellular function. | Biochemistry 20071218 |
| Structure/function analysis of the interaction of adenomatous polyposis coli with DNA polymerase beta and its implications for base excision repair. | Biochemistry 20071211 |
| Biological significance of DNA adducts investigated by simultaneous analysis of different endpoints of genotoxicity in L5178Y mouse lymphoma cells treated with methyl methanesulfonate. | Mutation research 20071201 |
| Genotoxicity and antigenotoxicity of cashew (Anacardium occidentale L.) in V79 cells. | Toxicology in vitro : an international journal published in association with BIBRA 20071201 |
| Effect of safranal, a constituent of Crocus sativus (saffron), on methyl methanesulfonate (MMS)-induced DNA damage in mouse organs: an alkaline single-cell gel electrophoresis (comet) assay. | DNA and cell biology 20071201 |
| Role of DNA mismatch repair and double-strand break repair in genome stability and antifungal drug resistance in Candida albicans. | Eukaryotic cell 20071201 |
| Amelioration of cognitive impairment in the type-2 diabetic mouse by the angiotensin II type-1 receptor blocker candesartan. | Hypertension (Dallas, Tex. : 1979) 20071201 |
| The protein degradation response of Saccharomyces cerevisiae to classical DNA-damaging agents. | Chemical research in toxicology 20071201 |
| Novel roles for selected genes in meiotic DNA processing. | PLoS genetics 20071201 |
| Differential susceptibility of rat embryos to methyl methanesulfonate during the pregastrulation period. | The Journal of toxicological sciences 20071201 |
| Involvement of 3-methyladenine DNA glycosylases Mag1p and Mag2p in base excision repair of methyl methanesulfonate-damaged DNA in the fission yeast Schizosaccharomyces pombe. | Genes & genetic systems 20071201 |
| Base excision DNA repair defect in Gadd45a-deficient cells. | Oncogene 20071129 |
| Crystal structure and DNA repair activities of the AP endonuclease from Leishmania major. | Journal of molecular biology 20071102 |
| A mutation in EXO1 defines separable roles in DNA mismatch repair and post-replication repair. | DNA repair 20071101 |
| Histone H1 variant, H1R is involved in DNA damage response. | DNA repair 20071101 |
| SAD2, an importin -like protein, is required for UV-B response in Arabidopsis by mediating MYB4 nuclear trafficking. | The Plant cell 20071101 |
| Gas-phase structure, rotational barrier, and vibrational properties of methyl methanethiosulfonate, CH3SO2SCH3: an experimental and computational study. | The journal of physical chemistry. A 20071004 |
| Silencing of endo-exonuclease expression sensitizes mouse B16F10 melanoma cells to DNA damaging agents. | Investigational new drugs 20071001 |
| Adenomatous polyposis coli-mediated hypersensitivity of mouse embryonic fibroblast cell lines to methylmethane sulfonate treatment: implication of base excision repair pathways. | Carcinogenesis 20071001 |
| ReProComet: a new in vitro method to assess DNA damage in mammalian sperm. | Toxicological sciences : an official journal of the Society of Toxicology 20071001 |
| Nutrient-sensitive mitochondrial NAD+ levels dictate cell survival. | Cell 20070921 |
| Genome-wide gene expression profiling suggests distinct radiation susceptibilities in sporadic and post-Chernobyl papillary thyroid cancers. | British journal of cancer 20070911 |
| Identification of sequences that target BRCA1 to nuclear foci following alkylative DNA damage. | Cellular signalling 20070901 |
| Identification of cysteines in rat organic cation transporters rOCT1 (C322, C451) and rOCT2 (C451) critical for transport activity and substrate affinity. | American journal of physiology. Renal physiology 20070901 |
| Specific transcriptional responses induced by 8-methoxypsoralen and UVA in yeast. | FEMS yeast research 20070901 |
| Phosphorylation of Slx4 by Mec1 and Tel1 regulates the single-strand annealing mode of DNA repair in budding yeast. | Molecular and cellular biology 20070901 |
| Neurosprora crassa RAD5 homologue, mus-41, inactivation results in higher sensitivity to mutagens but has little effect on PCNA-ubiquitylation in response to UV-irradiation. | Current genetics 20070901 |
| Tissue factor coagulant function is enhanced by protein-disulfide isomerase independent of oxidoreductase activity. | The Journal of biological chemistry 20070831 |
| Alkylating agent methyl methanesulfonate (MMS) induces a wave of global protein hyperacetylation: implications in cancer cell death. | Biochemical and biophysical research communications 20070824 |
| Lycopene activity against chemically induced DNA damage in Chinese hamster ovary cells. | Toxicology in vitro : an international journal published in association with BIBRA 20070801 |
| Nicotinamidase activity is important for germination. | The Plant journal : for cell and molecular biology 20070801 |
| Bacillus subtilis RecG branch migration translocase is required for DNA repair and chromosomal segregation. | Molecular microbiology 20070801 |
| The role of AtMUS81 in interference-insensitive crossovers in A. thaliana. | PLoS genetics 20070801 |
| A screen for suppressors of gross chromosomal rearrangements identifies a conserved role for PLP in preventing DNA lesions. | PLoS genetics 20070801 |
| DNA damage measured by comet assay and 8-OH-dG formation related to blood chemical analyses in aged rats. | The Journal of toxicological sciences 20070801 |
| The phosphoinositide 3-kinase pathway in human cancer: genetic alterations and therapeutic implications. | Current genomics 20070801 |
| Antioxidant activity of diphenyl diselenide prevents the genotoxicity of several mutagens in Chinese hamster V79 cells. | Mutation research 20070710 |
| Sea urchin embryo as a model for analysis of the signaling pathways linking DNA damage checkpoint, DNA repair and apoptosis. | Cellular and molecular life sciences : CMLS 20070701 |
| Development of a highly efficient gene targeting system induced by transient repression of YKU80 expression in Candida glabrata. | Eukaryotic cell 20070701 |
| Freshwater planarians as novel organisms for genotoxicity testing: Analysis of chromosome aberrations. | Environmental and molecular mutagenesis 20070701 |
| Induction of V(D)J-mediated recombination of an extrachromosomal substrate following exposure to DNA-damaging agents. | Environmental and molecular mutagenesis 20070701 |
| XRCC1 down-regulation in human cells leads to DNA-damaging agent hypersensitivity, elevated sister chromatid exchange, and reduced survival of BRCA2 mutant cells. | Environmental and molecular mutagenesis 20070701 |
| In vitro micronucleus assay scored by flow cytometry provides a comprehensive evaluation of cytogenetic damage and cytotoxicity. | Mutation research 20070615 |
| Functional and genetic analysis of the Saccharomyces cerevisiae RNC1/TRM2: evidences for its involvement in DNA double-strand break repair. | Molecular and cellular biochemistry 20070601 |
| ATR signaling mediates an S-phase checkpoint after inhibition of poly(ADP-ribose) polymerase activity. | DNA repair 20070601 |
| The novel gene mus7(+) is involved in the repair of replication-associated DNA damage in fission yeast. | DNA repair 20070601 |
| Analysis of DNA repair and recombination responses in mouse cells depleted for Brca2 by SiRNA. | DNA repair 20070601 |
| WRN functions in a RAD18-dependent damage avoidance pathway. | Biological & pharmaceutical bulletin 20070601 |
| Evidence that a RecQ helicase slows senescence by resolving recombining telomeres. | PLoS biology 20070601 |
| A novel DNA damage response: rapid degradation of the p12 subunit of dna polymerase delta. | The Journal of biological chemistry 20070525 |
| Investigation of the mutagenic and antimutagenic effects of Origanum compactum essential oil and some of its constituents. | Mutation research 20070518 |
| Nitric oxide donors attenuate clongenic potential in rat C6 glioma cells treated with alkylating chemotherapeutic agents. | Neuroscience letters 20070511 |
| Schistosoma mansoni: the IMP4 gene is involved in DNA repair/tolerance after treatment with alkylating agent methyl methane sulfonate. | Experimental parasitology 20070501 |
| Dose-response relationships and statistical performance of a battery of bacterial gene profiling assays. | Applied microbiology and biotechnology 20070501 |
| Protective effect of DCTN (trans-dehydrocrotonin) against induction of micronuclei and apoptosis by different mutagenic agents in vitro. | Mutation research 20070420 |
| Mechanistic influences for mutation induction curves after exposure to DNA-reactive carcinogens. | Cancer research 20070415 |
| Hypersensitivity phenotypes associated with genetic and synthetic inhibitor-induced base excision repair deficiency. | DNA repair 20070401 |
| Crosstalk between the subunits of the homodimeric enzyme triosephosphate isomerase. | Proteins 20070401 |
| Does s-methyl methanethiosulfonate trap the thiol-disulfide state of proteins? | Antioxidants & redox signaling 20070401 |
| Cooperative roles of vertebrate Fbh1 and Blm DNA helicases in avoidance of crossovers during recombination initiated by replication fork collapse. | Molecular and cellular biology 20070401 |
| Multiple-pathway analysis of double-strand break repair mutations in Drosophila. | PLoS genetics 20070401 |
| Rad50 is involved in MMS-induced recombination between homologous chromosomes in mitotic cells. | Genes & genetic systems 20070401 |
| The Prp19/Pso4 core complex undergoes ubiquitylation and structural alterations in response to DNA damage. | Biochemical and biophysical research communications 20070323 |
| An essential role for Drosophila hus1 in somatic and meiotic DNA damage responses. | Journal of cell science 20070315 |
| Modelling the probability distribution of the number of DNA double-strand breaks due to sporadic alkylation of nucleotide bases. | Journal of theoretical biology 20070307 |
| Chl1 and Ctf4 are required for damage-induced recombinations. | Biochemical and biophysical research communications 20070302 |
| Is the repair of oxidative DNA base modifications inducible by a preceding DNA damage induction? | DNA repair 20070301 |
| Global protein expression profiling of budding yeast in response to DNA damage. | Yeast (Chichester, England) 20070301 |
| Cyclosporin A potentiates the cytotoxic effects of methyl methanesulphonate in HL-60 and K562 cells. | Alternatives to laboratory animals : ATLA 20070301 |
| Anticancer effects of four varieties of muscadine grape. | Journal of medicinal food 20070301 |
| The effect of dietary folic acid deficiency on the cytotoxic and mutagenic responses to methyl methanesulfonate in wild-type and in 3-methyladenine DNA glycosylase-deficient Aag null mice. | Mutation research 20070203 |
| Rtt109 acetylates histone H3 lysine 56 and functions in DNA replication. | Science (New York, N.Y.) 20070202 |
| Regulation of Cdx2 expression by promoter methylation, and effects of Cdx2 transfection on morphology and gene expression of human esophageal epithelial cells. | Carcinogenesis 20070201 |
| Lead promotes abasic site accumulation and co-mutagenesis in mammalian cells by inhibiting the major abasic endonuclease Ape1. | Molecular carcinogenesis 20070201 |
| A role for the yeast cell cycle/splicing factor Cdc40 in the G1/S transition. | Current genetics 20070201 |
| Systematic pathway analysis using high-resolution fitness profiling of combinatorial gene deletions. | Nature genetics 20070201 |
| [Cell phenotypes of a mutant in the gene encoding a Rad51 paralog in fission yeast]. | Genetika 20070201 |
| Involvement of mitochondrial-targeted RecA in the repair of mitochondrial DNA in the moss, Physcomitrella patens. | Genes & genetic systems 20070201 |
| Doxorubicin down-regulates Kruppel-associated box domain-associated protein 1 sumoylation that relieves its transcription repression on p21WAF1/CIP1 in breast cancer MCF-7 cells. | The Journal of biological chemistry 20070119 |
| Properties of the type B histone acetyltransferase Hat1: H4 tail interaction, site preference, and involvement in DNA repair. | The Journal of biological chemistry 20070112 |
| Knockdown of ribosomal protein S3 protects human cells from genotoxic stress. | DNA repair 20070104 |
| The protein kinase TOUSLED is required for maintenance of transcriptional gene silencing in Arabidopsis. | EMBO reports 20070101 |
| Human monocytes, but not dendritic cells derived from them, are defective in base excision repair and hypersensitive to methylating agents. | Cancer research 20070101 |
| Global analysis of functional surfaces of core histones with comprehensive point mutants. | Genes to cells : devoted to molecular & cellular mechanisms 20070101 |
| Reduction of gene repair by selenomethionine with the use of single-stranded oligonucleotides. | BMC molecular biology 20070101 |
| A dominant-negative form of the major human abasic endonuclease enhances cellular sensitivity to laboratory and clinical DNA-damaging agents. | Molecular cancer research : MCR 20070101 |
| Manipulation of cell cycle progression can counteract the apparent loss of correction frequency following oligonucleotide-directed gene repair. | BMC molecular biology 20070101 |
| Quantitation of lower levels of the DNA adduct of thymidylyl(3'-5')thymidine methyl phosphotriester by liquid chromatography/negative atmospheric pressure chemical ionization tandem mass spectrometry. | Rapid communications in mass spectrometry : RCM 20070101 |
| Genome analysis of DNA repair genes in the alpha proteobacterium Caulobacter crescentus. | BMC microbiology 20070101 |
| Stripped-down DNA repair in a highly reduced parasite. | BMC molecular biology 20070101 |
| Colony size measurement of the yeast gene deletion strains for functional genomics. | BMC bioinformatics 20070101 |
| Lack of effect of prior treatment with fluoride on genotoxicity of two chemical agents in vitro. | Caries research 20070101 |
| Global transcriptional responses of fission and budding yeast to changes in copper and iron levels: a comparative study. | Genome biology 20070101 |
| ATM-mediated transcriptional and developmental responses to gamma-rays in Arabidopsis. | PloS one 20070101 |
| Gene expression profiling of long-lived dwarf mice: longevity-associated genes and relationships with diet, gender and aging. | BMC genomics 20070101 |
| DNA damage repair is unaffected by mimicked heterozygous levels of BRCA2 in HT-29 cells. | International journal of biological sciences 20070101 |
| Transcriptional networks in S. cerevisiae linked to an accumulation of base excision repair intermediates. | PloS one 20070101 |
| Checkpoint independence of most DNA replication origins in fission yeast. | BMC molecular biology 20070101 |
| Regulation of heme oxygenase-1 mRNA deadenylation and turnover in NIH3T3 cells by nitrosative or alkylation stress. | BMC molecular biology 20070101 |
| Shiitake (Lentinula edodes (Berkeley) Pegler) extracts as a modulator of micronuclei induced in HEp-2 cells. | Toxicology in vitro : an international journal published in association with BIBRA 20061201 |
| In vitro genotoxicity and cytotoxicity of benzalkonium chloride. | Toxicology in vitro : an international journal published in association with BIBRA 20061201 |
| Four human FANCG polymorphic variants show normal biological function in hamster CHO cells. | Mutation research 20061201 |
| DNA damage checkpoints are involved in postreplication repair. | Genetics 20061201 |
| Deletion of the chromatin remodeling gene SPT10 sensitizes yeast cells to a subclass of DNA-damaging agents. | Environmental and molecular mutagenesis 20061201 |
| DNA damage by ochratoxin A in rat kidney assessed by the alkaline comet assay. | Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20061201 |
| Methylating agents and DNA repair responses: Methylated bases and sources of strand breaks. | Chemical research in toxicology 20061201 |
| Modulation of chromosome damage localization by DNA replication timing. | International journal of radiation biology 20061201 |
| Lung cell fiber evanescent wave spectroscopic biosensing of inhalation health hazards. | Biotechnology and bioengineering 20061105 |
| Drosophila mus301/spindle-C encodes a helicase with an essential role in double-strand DNA break repair and meiotic progression. | Genetics 20061101 |
| Correlated resistance to glucose deprivation and cytotoxic agents in fibroblast cell lines from long-lived pituitary dwarf mice. | Mechanisms of ageing and development 20061101 |
| Employing libraries of zinc finger artificial transcription factors to screen for homologous recombination mutants in Arabidopsis. | The Plant journal : for cell and molecular biology 20061101 |
| Functional relationships between Rad18 and WRNIP1 in vertebrate cells. | Biological & pharmaceutical bulletin 20061101 |
| Characterization of a second proliferating cell nuclear antigen (PCNA2) from Drosophila melanogaster. | The FEBS journal 20061101 |
| A role for PCNA ubiquitination in immunoglobulin hypermutation. | PLoS biology 20061101 |
| Genotoxicants target distinct molecular networks in neonatal neurons. | Environmental health perspectives 20061101 |
| TATA-binding protein-related factor 2 is localized in the cytoplasm of mammalian cells and much of it migrates to the nucleus in response to genotoxic agents. | Molecules and cells 20061031 |
| Cellular characterization of cells from the Fanconi anemia complementation group, FA-D1/BRCA2. | Mutation research 20061010 |
| Evaluation of antimutagenic activity and mechanisms of action of beta-glucan from barley, in CHO-k1 and HTC cell lines using the micronucleus test. | Toxicology in vitro : an international journal published in association with BIBRA 20061001 |
| Arabidopsis SPO11-2 functions with SPO11-1 in meiotic recombination. | The Plant journal : for cell and molecular biology 20061001 |
| Cell size checkpoint control by the retinoblastoma tumor suppressor pathway. | PLoS genetics 20061001 |
| Both the basal transcriptional activity of the GADD45A gene and its enhancement after ionizing irradiation are mediated by AP-1 element. | Biochimica et biophysica acta 20061001 |
| Identification of a stable flavin-thiolate adduct in heterotetrameric sarcosine oxidase. | Journal of molecular biology 20060929 |
| Yeast recombination factor Rdh54 functionally interacts with the Rad51 recombinase and catalyzes Rad51 removal from DNA. | The Journal of biological chemistry 20060908 |
| The role of Schizosaccharomyces pombe DNA repair enzymes Apn1p and Uve1p in the base excision repair of apurinic/apyrimidinic sites. | Biochemical and biophysical research communications 20060908 |
| Small-molecule inhibitor of p53 binding to mitochondria protects mice from gamma radiation. | Nature chemical biology 20060901 |
| Meiotic chromosome synapsis-promoting proteins antagonize the anti-crossover activity of sgs1. | PLoS genetics 20060901 |
| [The tk gene mutation analysis in WTK1 cell line by multiplex PCR]. | Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20060901 |
| Heritability of DNA-damage-induced apoptosis and its relationship with age in lymphocytes from female twins. | British journal of cancer 20060821 |
| Cross-talk between nucleotide excision and homologous recombination DNA repair pathways in the mechanism of action of antitumor trabectedin. | Cancer research 20060815 |
| The Neurospora checkpoint kinase 2: a regulatory link between the circadian and cell cycles. | Science (New York, N.Y.) 20060804 |
| Evaluation of the alkaline Comet assay conducted with the wetlands plant Bacopa monnieri L. as a model for ecogenotoxicity assessment. | Environmental and molecular mutagenesis 20060801 |
| Antimicrobial endodontic compounds do not modulate alkylation-induced genotoxicity and oxidative stress in vitro. | Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 20060801 |
| Arsenic exposure is associated with decreased DNA repair in vitro and in individuals exposed to drinking water arsenic. | Environmental health perspectives 20060801 |
| Antigenotoxic effects of three essential oils in diploid yeast (Saccharomyces cerevisiae) after treatments with UVC radiation, 8-MOP plus UVA and MMS. | Mutation research 20060714 |
| A high-throughput method to measure the sensitivity of yeast cells to genotoxic agents in liquid cultures. | Mutation research 20060714 |
| Characterization of four RecQ homologues from rice (Oryza sativa L. cv. Nipponbare). | Biochemical and biophysical research communications 20060714 |
| Histone acetyltransferase 1 is dispensable for replication-coupled chromatin assembly but contributes to recover DNA damages created following replication blockage in vertebrate cells. | Biochemical and biophysical research communications 20060714 |
| Development of the in vivo chromosome aberration assay in oyster (Crassostrea gigas) embryo-larvae for genotoxicity assessment. | Marine environmental research 20060701 |
| Angiotensin II type-2 receptor stimulation prevents neural damage by transcriptional activation of methyl methanesulfonate sensitive 2. | Hypertension (Dallas, Tex. : 1979) 20060701 |
| Kre29p is a novel nuclear protein involved in DNA repair and mitotic fidelity in Candida glabrata. | Current genetics 20060701 |
| Lysine 63-polyubiquitination guards against translesion synthesis-induced mutations. | PLoS genetics 20060701 |
| The Saccharomyces cerevisiae orthologue of the human protein phosphatase 4 core regulatory subunit R2 confers resistance to the anticancer drug cisplatin. | The FEBS journal 20060701 |
| Genotoxic effects of chromium(VI) and cadmium(II) in human blood lymphocytes using the electron microscopy in situ end-labeling (EM-ISEL) assay. | Toxicology in vitro : an international journal published in association with BIBRA 20060601 |
| Protective effects of garlic sulfur compounds against DNA damage induced by direct- and indirect-acting genotoxic agents in HepG2 cells. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20060601 |
| Anti-clastogenic effect of beta-glucan extracted from barley towards chemically induced DNA damage in rodent cells. | Human & experimental toxicology 20060601 |
| Longevity in mice: is stress resistance a common factor? | Age (Dordrecht, Netherlands) 20060601 |
| A systems approach to mapping DNA damage response pathways. | Science (New York, N.Y.) 20060519 |
| P21Cip1/WAF1 downregulation is required for efficient PCNA ubiquitination after UV irradiation. | Oncogene 20060511 |
| Esc4/Rtt107 and the control of recombination during replication. | DNA repair 20060510 |
| hOGG1 recognizes oxidative damage using the comet assay with greater specificity than FPG or ENDOIII. | Mutagenesis 20060501 |
| Characterization of T-DNA insertion mutants and RNAi silenced plants of Arabidopsis thaliana UV-damaged DNA binding protein 2 (AtUV-DDB2). | Plant molecular biology 20060501 |
| Ecological-genetic feedback in DNA repair in wild barley, Hordeum spontaneum. | Genetica 20060501 |
| DNA damage evaluated by gammaH2AX foci formation by a selective group of chemical/physical stressors. | Mutation research 20060430 |
| Drosophila DNA polymerase zeta interacts with recombination repair protein 1, the Drosophila homologue of human abasic endonuclease 1. | The Journal of biological chemistry 20060428 |
| The cullin Rtt101p promotes replication fork progression through damaged DNA and natural pause sites. | Current biology : CB 20060418 |
| Posttranscriptional derepression of GADD45alpha by genotoxic stress. | Molecular cell 20060407 |
| Simultaneous quantitation of 7-methyl- and O6-methylguanine adducts in DNA by liquid chromatography-positive electrospray tandem mass spectrometry. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060403 |
| A stress regulatory network for co-ordinated activation of proteasome expression mediated by yeast heat shock transcription factor. | Molecular microbiology 20060401 |
| Disulfiram irreversibly aggregates betaine aldehyde dehydrogenase--a potential target for antimicrobial agents against Pseudomonas aeruginosa. | Biochemical and biophysical research communications 20060310 |
| Genotoxicity evaluation of kaurenoic acid, a bioactive diterpenoid present in Copaiba oil. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20060301 |
| A new protein superfamily includes two novel 3-methyladenine DNA glycosylases from Bacillus cereus, AlkC and AlkD. | Molecular microbiology 20060301 |
| XRCC1 genotype and breast cancer: functional studies and epidemiologic data show interactions between XRCC1 codon 280 His and smoking. | Cancer research 20060301 |
| DSS1 is required for the stability of BRCA2. | Oncogene 20060223 |
| Fructose-1,6-bisphosphatase mediates cellular responses to DNA damage and aging in Saccharomyces cerevisiae. | Mutation research 20060222 |
| Mutator phenotypes caused by substitution at a conserved motif A residue in eukaryotic DNA polymerase delta. | The Journal of biological chemistry 20060217 |
| AlkB dioxygenase in preventing MMS-induced mutagenesis in Escherichia coli: effect of Pol V and AlkA proteins. | DNA repair 20060203 |
| Role of DNA polymerase theta in tolerance of endogenous and exogenous DNA damage in mouse B cells. | Genes to cells : devoted to molecular & cellular mechanisms 20060201 |
| Fibroblasts from long-lived Snell dwarf mice are resistant to oxygen-induced in vitro growth arrest. | Aging cell 20060201 |
| [Effects of overexpression of human pol-beta on cellular response to DNA damage]. | Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 20060201 |
| Involvement of vertebrate Polkappa in translesion DNA synthesis across DNA monoalkylation damage. | The Journal of biological chemistry 20060127 |
| In vitro micronucleus scoring by flow cytometry: differential staining of micronuclei versus apoptotic and necrotic chromatin enhances assay reliability. | Environmental and molecular mutagenesis 20060101 |
| DNA polymerase 4 of Saccharomyces cerevisiae is important for accurate repair of methyl-methanesulfonate-induced DNA damage. | Genetics 20060101 |
| DNA strand breaks are not induced in human cells exposed to 2.1425 GHz band CW and W-CDMA modulated radiofrequency fields allocated to mobile radio base stations. | Bioelectromagnetics 20060101 |
| Loss of DNA polymerase zeta causes chromosomal instability in mammalian cells. | Cancer research 20060101 |
| The akuB(KU80) mutant deficient for nonhomologous end joining is a powerful tool for analyzing pathogenicity in Aspergillus fumigatus. | Eukaryotic cell 20060101 |
| Drosophila damaged DNA binding protein 1 contributes to genome stability in somatic cells. | Journal of biochemistry 20060101 |
| Lack of in vitro genotoxicity of povidone-iodine in solution, in ointment or in a liposomal formulation (Repithel). | Dermatology (Basel, Switzerland) 20060101 |
| Common features and interesting differences in transcriptional responses to secretion stress in the fungi Trichoderma reesei and Saccharomyces cerevisiae. | BMC genomics 20060101 |
| Mutator specificity of Escherichia coli alkB117 allele. | Acta biochimica Polonica 20060101 |
| Non-random clustering of stress-related genes during evolution of the S. cerevisiae genome. | BMC evolutionary biology 20060101 |
| MicroArray Facility: a laboratory information management system with extended support for Nylon based technologies. | BMC genomics 20060101 |
| Colostrinin decreases spontaneous and induced mutation frequencies at the hprt locus in Chinese hamster V79 cells. | Journal of experimental therapeutics & oncology 20060101 |
| Microarray expression analysis of meiosis and microsporogenesis in hexaploid bread wheat. | BMC genomics 20060101 |
| Analyzing the dose-dependence of the Saccharomyces cerevisiae global transcriptional response to methyl methanesulfonate and ionizing radiation. | BMC genomics 20060101 |
| The DNA-damage signature in Saccharomyces cerevisiae is associated with single-strand breaks in DNA. | BMC genomics 20060101 |
| Natural microbial polysaccharide sulphoethyl glucan as antigenotoxic and cancer preventing agent. | Neoplasma 20060101 |
| Maf1, a new player in the regulation of human RNA polymerase III transcription. | PloS one 20060101 |
| Hsk1-Dfp1/Him1, the Cdc7-Dbf4 kinase in Schizosaccharomyces pombe, associates with Swi1, a component of the replication fork protection complex. | The Journal of biological chemistry 20051230 |
| Conformation-dependent inactivation of human betaine-homocysteine S-methyltransferase by hydrogen peroxide in vitro. | The Biochemical journal 20051215 |
| Mutations in Mre11 phosphoesterase motif I that impair Saccharomyces cerevisiae Mre11-Rad50-Xrs2 complex stability in addition to nuclease activity. | Genetics 20051201 |
| The yeast histone chaperone chromatin assembly factor 1 protects against double-strand DNA-damaging agents. | Genetics 20051201 |
| Involvement of polyubiquitin chains via specific chain linkages in stress response in mammalian cells. | Biological & pharmaceutical bulletin 20051201 |
| A network of multi-tasking proteins at the DNA replication fork preserves genome stability. | PLoS genetics 20051201 |
| The role of natural biopolymers in genotoxicity of mutagens/carcinogens elimination. | Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia 20051201 |
| Saccharomyces cerevisiae RAD53 (CHK2) but not CHK1 is required for double-strand break-initiated SCE and DNA damage-associated SCE after exposure to X rays and chemical agents. | DNA repair 20051121 |
| Roles of base excision repair enzymes Nth1p and Apn2p from Schizosaccharomyces pombe in processing alkylation and oxidative DNA damage. | DNA repair 20051121 |
| Sensitization of human carcinoma cells to alkylating agents by small interfering RNA suppression of 3-alkyladenine-DNA glycosylase. | Cancer research 20051115 |
| Mutations in a conserved replication protein suppress transcriptional gene silencing in a DNA-methylation-independent manner in Arabidopsis. | Current biology : CB 20051108 |
| The csnD/csnE signalosome genes are involved in the Aspergillus nidulans DNA damage response. | Genetics 20051101 |
| Cellular dynamics and modulation of WRN protein is DNA damage specific. | Mechanisms of ageing and development 20051101 |
| A mutation in yeast Tel1p that causes differential effects on the DNA damage checkpoint and telomere maintenance. | Current genetics 20051101 |
| Ion/molecule reactions in a miniature RIT mass spectrometer. | Journal of mass spectrometry : JMS 20051101 |
| HIM1, a new yeast Saccharomyces cerevisiae gene playing a role in control of spontaneous and induced mutagenesis. | Mutation research 20051015 |
| Studying the synergistic damage effects induced by 1.8 GHz radiofrequency field radiation (RFR) with four chemical mutagens on human lymphocyte DNA using comet assay in vitro. | Mutation research 20051015 |
| Enhanced stimulation of chromosomal translocations and sister chromatid exchanges by either HO-induced double-strand breaks or ionizing radiation in Saccharomyces cerevisiae yku70 mutants. | Mutation research 20051015 |
| Relationships between genomic, cell cycle, and mutagenic responses of TK6 cells exposed to DNA damaging chemicals. | Mutation research 20051015 |
| Induced mutation spectra at the upp locus in Salmonella typhimurium: response of the target gene in the FU assay to mechanistically different mutagens. | Mutation research 20051015 |
| Evaluation of testicular toxicity and sperm morphology in rats treated with methyl methanesulphonate (MMS). | The Journal of reproduction and development 20051001 |
| The C. elegans ortholog of mammalian Ku70, interacts with insulin-like signaling to modulate stress resistance and life span. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20051001 |
| REV1 mediated mutagenesis in base excision repair deficient mouse fibroblast. | DNA repair 20050928 |
| Involvement of poly(ADP-ribose) polymerase activity in regulating Chk1-dependent apoptotic cell death. | DNA repair 20050928 |
| Mrc1 and Tof1 promote replication fork progression and recovery independently of Rad53. | Molecular cell 20050902 |
| Dynamic changes in protein-protein interaction and protein phosphorylation probed with amine-reactive isotope tag. | Molecular & cellular proteomics : MCP 20050901 |
| Apaf-1 deficient mouse fibroblasts are resistant to MNNG and MMS-induced apoptotic death without attenuation of Bcl-2 decline. | Toxicology and applied pharmacology 20050901 |
| Role of the Schizosaccharomyces pombe F-Box DNA helicase in processing recombination intermediates. | Molecular and cellular biology 20050901 |
| Arabidopsis RecQI4A suppresses homologous recombination and modulates DNA damage responses. | The Plant journal : for cell and molecular biology 20050901 |
| REC, Drosophila MCM8, drives formation of meiotic crossovers. | PLoS genetics 20050901 |
| Genotoxicity sensor response correlated with DNA nucleobase damage rates measured by LC-MS. | Molecular bioSystems 20050901 |
| Differentiating mechanisms of toxicity using global gene expression analysis in Saccharomyces cerevisiae. | Mutation research 20050804 |
| Different types of combination effects for the induction of micronuclei in mouse lymphoma cells by binary mixtures of the genotoxic agents MMS, MNU, and genistein. | Toxicological sciences : an official journal of the Society of Toxicology 20050801 |
| Cytotoxicity and gene induction by some essential oils in the yeast Saccharomyces cerevisiae. | Mutation research 20050801 |
| Inhibition of c-Jun-N-terminal-kinase sensitizes tumor cells to CD95-induced apoptosis and induces G2/M cell cycle arrest. | Cancer research 20050801 |
| Genome-wide requirements for resistance to functionally distinct DNA-damaging agents. | PLoS genetics 20050801 |
| Thiol-disulphide interchange in tubulin: kinetics and the effect on polymerization. | The Biochemical journal 20050715 |
| Fibroblast cell lines from young adult mice of long-lived mutant strains are resistant to multiple forms of stress. | American journal of physiology. Endocrinology and metabolism 20050701 |
| XRCC1 and DNA polymerase beta interaction contributes to cellular alkylating-agent resistance and single-strand break repair. | Journal of cellular biochemistry 20050701 |
| Validation of Drosophila melanogaster as an in vivo model for genotoxicity assessment using modified alkaline Comet assay. | Mutagenesis 20050701 |
| Genetic and physical interactions between Schizosaccharomyces pombe Mcl1 and Rad2, Dna2 and DNA polymerase alpha: evidence for a multifunctional role of Mcl1 in DNA replication and repair. | Current genetics 20050701 |
| Influence of orange juice over the genotoxicity induced by alkylating agents: an in vivo analysis. | Mutagenesis 20050701 |
| Two types of replication protein A in seed plants. | The FEBS journal 20050701 |
| Antioxidative and antigenotoxic effects of Japanese horse chestnut (Aesculus turbinata) seeds. | The Journal of veterinary medical science 20050701 |
| Antigenotoxic effect of allicin against methyl methanesulphonate induced genotoxic damage. | Journal of environmental biology 20050701 |
| Stress-specific signatures: expression profiling of p53 wild-type and -null human cells. | Oncogene 20050630 |
| Overexpression of Rad51 inhibits double-strand break-induced homologous recombination but does not affect gene conversion tract lengths. | DNA repair 20050608 |
| Evaluation of liver and peripheral blood micronucleus assays with 9 chemicals using young rats. A study by the Collaborative Study Group for the Micronucleus Test (CSGMT)/Japanese Environmental Mutagen Society (JEMS)-Mammalian Mutagenicity Study Group (MMS). | Mutation research 20050606 |
| Characterization of chemically induced hepatotoxicity in collagen sandwiches of rat hepatocytes. | Toxicological sciences : an official journal of the Society of Toxicology 20050601 |
| [Influence of 1.8 GHz microwave on DNA damage induced by 4 chemical mutagens]. | Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 20050601 |
| Possible repair action of Vitamin C on DNA damage induced by methyl methanesulfonate, cyclophosphamide, FeSO4 and CuSO4 in mouse blood cells in vivo. | Mutation research 20050502 |
| Influence of caspase activity on micronuclei detection: a possible role for caspase-3 in micronucleation. | Mutagenesis 20050501 |
| Evaluation of genotoxic effects in human peripheral blood leukocytes following an acute in vitro exposure to 900 MHz radiofrequency fields. | Bioelectromagnetics 20050501 |
| A time-course characterization of male reproductive toxicity in rats treated with methyl methanesulphonate (MMS). | The Journal of toxicological sciences 20050501 |
| Poly(ADP-ribose) polymerase activity prevents signaling pathways for cell cycle arrest after DNA methylating agent exposure. | The Journal of biological chemistry 20050422 |
| Mitochondrial targeting of human O6-methylguanine DNA methyltransferase protects against cell killing by chemotherapeutic alkylating agents. | Cancer research 20050415 |
| Ubiquitin ligase activity of TFIIH and the transcriptional response to DNA damage. | Molecular cell 20050415 |
| Genetic network interactions among replication, repair and nuclear pore deficiencies in yeast. | DNA repair 20050404 |
| The Arg280His polymorphism in X-ray repair cross-complementing gene 1 impairs DNA repair ability. | Mutation research 20050404 |
| Activation of budding yeast replication origins and suppression of lethal DNA damage effects on origin function by ectopic expression of the co-chaperone protein Mge1. | The Journal of biological chemistry 20050401 |
| The Rad1-Rad10 complex promotes the production of gross chromosomal rearrangements from spontaneous DNA damage in Saccharomyces cerevisiae. | Genetics 20050401 |
| Quantitative measurement of DNA adducts using neutral hydrolysis and LC-MS. Validation of genotoxicity sensors. | Analytical chemistry 20050401 |
| MIT toxicogenomics research program. | Environmental health perspectives 20050401 |
| Characterisation of two novel fork-head gene homologues of Schizosaccharomyces pombe: their involvement in cell cycle and sexual differentiation. | Gene 20050328 |
| Induction of a cell stress response gene RTP801 by DNA damaging agent methyl methanesulfonate through CCAAT/enhancer binding protein. | Biochemistry 20050315 |
| Extensive chromosomal instability in Rad51d-deficient mouse cells. | Cancer research 20050315 |
| Genetic control of temperature preference in the nematode Caenorhabditis elegans. | Genetics 20050301 |
| Systematic, RNA-interference-mediated identification of mus-101 modifier genes in Caenorhabditis elegans. | Genetics 20050301 |
| The N-terminal region of the Schizosaccharomyces pombe RecQ helicase, Rqh1p, physically interacts with Topoisomerase III and is required for Rqh1p function. | Molecular genetics and genomics : MGG 20050301 |
| Expression of insulin-like growth factor-1 and insulin-like growth factor-1 receptors in EL4 lymphoma cells overexpressing growth hormone. | Cellular immunology 20050301 |
| Tumor suppressor APC blocks DNA polymerase beta-dependent strand displacement synthesis during long patch but not short patch base excision repair and increases sensitivity to methylmethane sulfonate. | The Journal of biological chemistry 20050225 |
| The ability of Sgs1 to interact with DNA topoisomerase III is essential for damage-induced recombination. | DNA repair 20050203 |
| Comet assay with nuclear extract incubation. | Analytical biochemistry 20050201 |
| Functional specialization of Chlamydomonas reinhardtii cytosolic thioredoxin h1 in the response to alkylation-induced DNA damage. | Eukaryotic cell 20050201 |
| Comparative study of the comet assay and the micronucleus test in amphibian larvae (Xenopus laevis) using benzo(a)pyrene, ethyl methanesulfonate, and methyl methanesulfonate: establishment of a positive control in the amphibian comet assay. | Environmental toxicology 20050201 |
| The identification and optimization of a N-hydroxy urea series of flap endonuclease 1 inhibitors. | Bioorganic & medicinal chemistry letters 20050117 |
| Role of Escherichia coli DnaK and DnaJ chaperones in spontaneous and induced mutagenesis and their effect on UmuC stability. | FEMS microbiology letters 20050115 |
| New insights into the Fanconi anemia pathway from an isogenic FancG hamster CHO mutant. | DNA repair 20050102 |
| The Saccharomyces cerevisiae PDS1 and RAD9 checkpoint genes control different DNA double-strand break repair pathways. | DNA repair 20050102 |
| Ccr4-not complex mRNA deadenylase activity contributes to DNA damage responses in Saccharomyces cerevisiae. | Genetics 20050101 |
| Effects of substrate specificity on initiating the base excision repair of N-methylpurines by variant human 3-methyladenine DNA glycosylases. | Chemical research in toxicology 20050101 |
| Differential adduction of proteins vs. deoxynucleosides by methyl methanesulfonate and 1-methyl-1-nitrosourea in vitro. | Rapid communications in mass spectrometry : RCM 20050101 |
| Correlation and prediction of gene expression level from amino acid and dipeptide composition of its protein. | BMC bioinformatics 20050101 |
| Genome-wide screening for genes whose deletions confer sensitivity to mutagenic purine base analogs in yeast. | BMC genetics 20050101 |
| A microarray study of MPP+-treated PC12 Cells: Mechanisms of toxicity (MOT) analysis using bioinformatics tools. | BMC bioinformatics 20050101 |
| The potential roles of p53 tumor suppressor in nucleotide excision repair (NER) and base excision repair (BER). | Experimental & molecular medicine 20041231 |
| Differential regulation of gene expression by RNA polymerase II in response to DNA damage. | Biochemical and biophysical research communications 20041217 |
| Increased genome instability and telomere length in the elg1-deficient Saccharomyces cerevisiae mutant are regulated by S-phase checkpoints. | Eukaryotic cell 20041201 |
| Enhancement of genotoxic effects in the comet assay with human blood samples by aphidicolin. | Toxicology letters 20041128 |
| DNA replication checkpoint control mediated by the spindle checkpoint protein Mad2p in fission yeast. | The Journal of biological chemistry 20041105 |
| 'Knock down' of DNA polymerase beta by RNA interference: recapitulation of null phenotype. | DNA repair 20041102 |
| The ataxia-oculomotor apraxia 1 gene product has a role distinct from ATM and interacts with the DNA strand break repair proteins XRCC1 and XRCC4. | DNA repair 20041102 |
| Rad62 protein functionally and physically associates with the smc5/smc6 protein complex and is required for chromosome integrity and recombination repair in fission yeast. | Molecular and cellular biology 20041101 |
| Brca1-deficient murine mammary epithelial cells have increased sensitivity to CDDP and MMS. | Cell cycle (Georgetown, Tex.) 20041101 |
| Antigenotoxic potential of glucomannan on four model test systems. | Cell biology and toxicology 20041101 |
| DNA damage-induced accumulation of Rad18 protein at stalled replication forks in mammalian cells involves upstream protein phosphorylation. | Biochemical and biophysical research communications 20041022 |
| Genetic variation in XRCC1, sun exposure, and risk of skin cancer. | British journal of cancer 20041018 |
| Hot spots for modulating toxicity identified by genomic phenotyping and localization mapping. | Molecular cell 20041008 |
| The hyper unequal sister chromatid recombination in an sgs1 mutant of budding yeast requires MSH2. | DNA repair 20041005 |
| Identification and characterization of the rlp1+, the novel Rad51 paralog in the fission yeast Schizosaccharomyces pombe. | DNA repair 20041005 |
| DNA polymerase beta lyase inhibitors from Maytenus putterlickoides. | Journal of natural products 20041001 |
| Identification of small molecule synthetic inhibitors of DNA polymerase beta by NMR chemical shift mapping. | The Journal of biological chemistry 20040917 |
| Effects of gemcitabine on APE/ref-1 endonuclease activity in pancreatic cancer cells, and the therapeutic potential of antisense oligonucleotides. | British journal of cancer 20040913 |
| Involvement of human p53 in induced intrachromosomal recombination in Saccharomyces cerevisiae. | Mutagenesis 20040901 |
| A novel yeast mutation, rad52-L89F, causes a specific defect in Rad51-independent recombination that correlates with a reduced ability of Rad52-L89F to interact with Rad59. | Genetics 20040901 |
| [TK locus mutation assay: comparison of L5178Y and TK6 cell lines]. | Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20040901 |
| Trace analysis of residual methyl methanesulfonate, ethyl methanesulfonate and isopropyl methanesulfonate in pharmaceuticals by capillary gas chromatography with flame ionization detection. | Journal of chromatography. A 20040813 |
| Transient adenoviral N-methylpurine DNA glycosylase overexpression imparts chemotherapeutic sensitivity to human breast cancer cells. | Molecular cancer therapeutics 20040801 |
| CDC7/DBF4 functions in the translesion synthesis branch of the RAD6 epistasis group in Saccharomyces cerevisiae. | Genetics 20040801 |
| Human SAD1 kinase is involved in UV-induced DNA damage checkpoint function. | The Journal of biological chemistry 20040723 |
| Construction of a recA mutant of Azospirillum lipoferum and involvement of recA in phase variation. | FEMS microbiology letters 20040715 |
| Relative cytotoxicity values at the lowest effective concentration for 12 positive chemicals in the in vitro micronucleus test utilizing Chinese hamster ovary cells. | Mutation research 20040711 |
| Regulation of mouse GADD34 gene transcription after DNA damaging agent methylmethane sulfonate. | Gene 20040707 |
| Preliminary evaluation of DNA damage related with the smoking habit measured by the comet assay in whole blood cells. | Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20040701 |
| Protein phosphatase 1, but not protein phosphatase 2A, dephosphorylates DNA-damaging stress-induced phospho-serine 15 of p53. | FEBS letters 20040604 |
| Regulatory mechanisms controlling biogenesis of ubiquitin and the proteasome. | FEBS letters 20040604 |
| Variation of the antimutagenicity effects of water extracts of Agaricus blazei Murrill in vitro. | Toxicology in vitro : an international journal published in association with BIBRA 20040601 |
| Evaluation of the genotoxic potential of the Casearia sylvestris extract on HTC and V79 cells by the comet assay. | Toxicology in vitro : an international journal published in association with BIBRA 20040601 |
| Human apurinic endonuclease 1 (APE1) expression and prognostic significance in osteosarcoma: enhanced sensitivity of osteosarcoma to DNA damaging agents using silencing RNA APE1 expression inhibition. | Molecular cancer therapeutics 20040601 |
| Saccharomyces cerevisiae RAD27 complements its Escherichia coli homolog in damage repair but not mutation avoidance. | Genes & genetic systems 20040601 |
| Identification of a gene expression profile that discriminates indirect-acting genotoxins from direct-acting genotoxins. | Mutation research 20040518 |
| Comet assay using mullet (Mugil sp.) and sea catfish (Netuma sp.) erythrocytes for the detection of genotoxic pollutants in aquatic environment. | Mutation research 20040509 |
| Visualization of altered replication dynamics after DNA damage in human cells. | The Journal of biological chemistry 20040507 |
| Profiles of gene expression changes in L5178Y mouse lymphoma cells treated with methyl methanesulfonate and sodium chloride. | Mutagenesis 20040501 |
| Characterization of the hamster FancG/Xrcc9 gene and mutations in CHO UV40 and NM3. | Mutagenesis 20040501 |
| Molecular aspects of plant adaptation to life in the Chernobyl zone. | Plant physiology 20040501 |
| Low concentrations of formaldehyde induce DNA damage and delay DNA repair after UV irradiation in human skin cells. | Experimental dermatology 20040501 |
| A large-scale screen for mutagen-sensitive loci in Drosophila. | Genetics 20040501 |
| Nitric oxide inhibits DNA-adduct excision in nucleotide excision repair. | Free radical biology & medicine 20040415 |
| The autoradiographic test for unscheduled DNA synthesis: a sensitive assay for the detection of DNA repair in the HepG2 cell line. | Mutation research 20040411 |
| The possible roles of the DNA helicase and C-terminal domains in RECQ5/QE: complementation study in yeast. | DNA repair 20040401 |
| SMC6 is required for MMS-induced interchromosomal and sister chromatid recombinations in Saccharomyces cerevisiae. | DNA repair 20040401 |
| Antigenotoxic effect of allicin against SCEs induced by methyl methanesulphonate in cultured mammalian cells. | Indian journal of experimental biology 20040401 |
| Yeast MPH1 gene functions in an error-free DNA damage bypass pathway that requires genes from Homologous recombination, but not from postreplicative repair. | Genetics 20040401 |
| Role of the nuclease activity of Saccharomyces cerevisiae Mre11 in repair of DNA double-strand breaks in mitotic cells. | Genetics 20040401 |
| Transcription factors NF-YA regulate the induction of human OGG1 following DNA-alkylating agent methylmethane sulfonate (MMS) treatment. | The Journal of biological chemistry 20040312 |
| Ubc9 is required for damage-tolerance and damage-induced interchromosomal homologous recombination in S. cerevisiae. | DNA repair 20040304 |
| The absence of a functional relationship between ATM and BLM, the components of BASC, in DT40 cells. | Biochimica et biophysica acta 20040302 |
| Coffee-mediated protective effects against directly acting genotoxins and gamma-radiation in mouse lymphoma cells. | Cell biology and toxicology 20040301 |
| The Neurospora crassa mus-19 gene is identical to the qde-3 gene, which encodes a RecQ homologue and is involved in recombination repair and postreplication repair. | Current genetics 20040201 |
| A domain of Rad9 specifically required for activation of Chk1 in budding yeast. | Journal of cell science 20040201 |
| Interchromatid and interhomolog recombination in Arabidopsis thaliana. | The Plant cell 20040201 |
| The biological effects of N3-methyladenine. | Journal of cellular biochemistry 20040201 |
| Physical and functional interactions between nucleotide excision repair and DNA damage checkpoint. | The EMBO journal 20040128 |
| Saccharomyces cerevisiae ubiquitin-like protein Rub1 conjugates to cullin proteins Rtt101 and Cul3 in vivo. | The Biochemical journal 20040115 |
| Discovering modes of action for therapeutic compounds using a genome-wide screen of yeast heterozygotes. | Cell 20040109 |
| Involvement of two endonuclease III homologs in the base excision repair pathway for the processing of DNA alkylation damage in Saccharomyces cerevisiae. | DNA repair 20040105 |
| A comprehensive evolutionary classification of proteins encoded in complete eukaryotic genomes. | Genome biology 20040101 |
| The inhibition of apoptosis in EL4 lymphoma cells overexpressing growth hormone. | Neuroimmunomodulation 20040101 |
| [Dynamics of some postreplication DNA repair proteins in carcinogen-damaged mammalian cells]. | Tsitologiia 20040101 |
| Investigations into the biological relevance of in vitro clastogenic and aneugenic activity. | Cytogenetic and genome research 20040101 |
| Systematic quantification of gene interactions by phenotypic array analysis. | Genome biology 20040101 |
| Network responses to DNA damaging agents. | DNA repair 20040101 |
| Inhibition of the human apurinic/apyrimidinic endonuclease (APE1) repair activity and sensitization of breast cancer cells to DNA alkylating agents with lucanthone. | Anticancer research 20040101 |
| Comparison of gene expression changes induced in mouse and human cells treated with direct-acting mutagens. | Environmental and molecular mutagenesis 20040101 |
| [Some properties of a mutant of Streptomyces globisporus 1912 supersensitive to ultraviolet radiation]. | Mikrobiolohichnyi zhurnal (Kiev, Ukraine : 1993) 20040101 |
| Fish as bioindicators to assess the effects of pollution in two southern Brazilian rivers using the Comet assay and micronucleus test. | Environmental and molecular mutagenesis 20040101 |
| Antimutagenic activity of berry extracts. | Journal of medicinal food 20040101 |
| The protective effect of mild hyperthermia against UV-mimetic agent 4-nitroquinoline-1-oxide (4NQO) in human colon cells. | Research communications in molecular pathology and pharmacology 20040101 |
| Elimination of methyl methanesulfonate (MMS)-induced micronuclei (MNS) under mild hyperthermia via p53-dependent pathway in human lymphoid cells. | Research communications in molecular pathology and pharmacology 20040101 |
| Methyl methanesulfonate. | Report on carcinogens : carcinogen profiles 20040101 |
| The Drosophila melanogaster DNA Ligase IV gene plays a crucial role in the repair of radiation-induced DNA double-strand breaks and acts synergistically with Rad54. | Genetics 20031201 |
| Modification of 1-substituents in the 2-azabicyclo[2.1.1]hexane ring system; approaches to potential nicotinic acetylcholine receptor ligands from 2,4-methanoproline derivatives. | The Journal of organic chemistry 20031128 |
| Comparison of checkpoint responses triggered by DNA polymerase inhibition versus DNA damaging agents. | Mutation research 20031127 |
| Mechanism-based inactivation of thioredoxin reductase from Plasmodium falciparum by Mannich bases. Implication for cytotoxicity. | Biochemistry 20031118 |
| Evidence in Escherichia coli that N3-methyladenine lesions and cytotoxicity induced by a minor groove binding methyl sulfonate ester can be modulated in vivo by netropsin. | Biochemistry 20031104 |
| Base excision repair intermediates induce p53-independent cytotoxic and genotoxic responses. | The Journal of biological chemistry 20031010 |
| Identification and molecular characterisation of DNA damaging agent induced expression of Plasmodium falciparum recombination protein PfRad51. | International journal for parasitology 20031001 |
| Recombinogenic effects of DNA-damaging agents are synergistically increased by transcription in Saccharomyces cerevisiae. New insights into transcription-associated recombination. | Genetics 20031001 |
| REC, a new member of the MCM-related protein family, is required for meiotic recombination in Drosophila. | Genes & genetic systems 20031001 |
| Lyn regulates the cell death response to ultraviolet radiation through c-Jun N terminal kinase-dependent Fas ligand activation. | Experimental cell research 20030910 |
| Dephosphorylation of histone gamma-H2AX during repair of DNA double-strand breaks in mammalian cells and its inhibition by calyculin A. | Radiation research 20030901 |
| Ku80 plays a role in non-homologous recombination but is not required for T-DNA integration in Arabidopsis. | The Plant journal : for cell and molecular biology 20030901 |
| Cadmium inhibits repair of UV-, methyl methanesulfonate- and N-methyl-N-nitrosourea-induced DNA damage in Chinese hamster ovary cells. | Mutation research 20030828 |
| The role of yeast DNA 3'-phosphatase Tpp1 and rad1/Rad10 endonuclease in processing spontaneous and induced base lesions. | The Journal of biological chemistry 20030815 |
| Nat3p and Mdm20p are required for function of yeast NatB Nalpha-terminal acetyltransferase and of actin and tropomyosin. | The Journal of biological chemistry 20030815 |
| Comparative scoring of micronucleated reticulocytes in rat peripheral blood by flow cytometry and microscopy. | Toxicological sciences : an official journal of the Society of Toxicology 20030801 |
| Anticlastogenic effect of aqueous extracts of Agaricus blazei on CHO-k1 cells, studying different developmental phases of the mushroom. | Toxicology in vitro : an international journal published in association with BIBRA 20030801 |
| Competition between the Rad50 complex and the Ku heterodimer reveals a role for Exo1 in processing double-strand breaks but not telomeres. | Molecular and cellular biology 20030801 |
| Human-yeast chimeric repair protein protects mammalian cells against alkylating agents: enhancement of MGMT protection. | Cancer gene therapy 20030801 |
| DNA ligase IV from a basidiomycete, Coprinus cinereus, and its expression during meiosis. | Microbiology (Reading, England) 20030801 |
| Tissue-dependent induction of heme oxygenase-1 and metallothionein-1/2 by methyl methanesulfonate. | The Journal of toxicological sciences 20030801 |
| [Effects of 2,450 MHz microwave on DNA damage induced by three chemical mutagens in vitro]. | Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 20030801 |
| High dosage Rhp51 suppression of the MMS sensitivity of DNA structure checkpoint mutants reveals a relationship between Crb2 and Rhp51. | Genes to cells : devoted to molecular & cellular mechanisms 20030701 |
| The recombination-deficient mutant RPA (rfa1-t11) is displaced slowly from single-stranded DNA by Rad51 protein. | The Journal of biological chemistry 20030627 |
| REX1, a novel gene required for DNA repair. | The Journal of biological chemistry 20030620 |
| Multiple roles of Rev3, the catalytic subunit of polzeta in maintaining genome stability in vertebrates. | The EMBO journal 20030616 |
| Extrachromosomal circular DNA of tandemly repeated genomic sequences in Drosophila. | Genome research 20030601 |
| Phenotypic analysis of separation-of-function alleles of MEI-41, Drosophila ATM/ATR. | Genetics 20030601 |
| Suppression of homologous recombination by the Saccharomyces cerevisiae linker histone. | Molecular cell 20030601 |
| Osmotic water permeability and regulatory volume decrease of rat thymocytes. | General physiology and biophysics 20030601 |
| Mutant casein kinase I (Hrr25p/Kti14p) abrogates the G1 cell cycle arrest induced by Kluyveromyces lactiszymocin in budding yeast. | Molecular genetics and genomics : MGG 20030501 |
| Arabidopsis RecQsim, a plant-specific member of the RecQ helicase family, can suppress the MMS hypersensitivity of the yeast sgs1 mutant. | Plant molecular biology 20030501 |
| Use of HepG2 cell line for direct or indirect mutagens screening: comparative investigation between comet and micronucleus assays. | Mutation research 20030420 |
| The Escherichia coli RecA protein complements recombination defective phenotype of the Saccharomyces cerevisiae rad52 mutant cells. | Yeast (Chichester, England) 20030415 |
| Independent roles of XRCC1's two BRCT motifs in recovery from methylation damage. | DNA repair 20030402 |
| Enhanced radiation and chemotherapy-mediated cell killing of human cancer cells by small inhibitory RNA silencing of DNA repair factors. | Cancer research 20030401 |
| A new Schizosaccharomyces pombe base excision repair mutant, nth1, reveals overlapping pathways for repair of DNA base damage. | Molecular microbiology 20030401 |
| Saccharomyces cerevisiae Dap1p, a novel DNA damage response protein related to the mammalian membrane-associated progesterone receptor. | Eukaryotic cell 20030401 |
| C/EBP family transcription factors are degraded by the proteasome but stabilized by forming dimer. | Oncogene 20030306 |
| Induction of genome instability by DNA damage in Saccharomyces cerevisiae. | DNA repair 20030301 |
| Budding yeast mms4 is epistatic with rad52 and the function of Mms4 can be replaced by a bacterial Holliday junction resolvase. | DNA repair 20030301 |
| Ionizing irradiation effects on S-phase in checkpoint mutants of the yeast Saccharomyces cerevisiae. | Current genetics 20030301 |
| Comet assay on gill cells and hemocytes from the blue mussel Mytilus edulis. | Ecotoxicology and environmental safety 20030301 |
| The Drosophila chk2 gene loki is essential for embryonic DNA double-strand-break checkpoints induced in S phase or G2. | Genetics 20030301 |
| The possible mechanism of action of ciclopirox olamine in the yeast Saccharomyces cerevisiae. | Molecules and cells 20030227 |
| Apoptosis, ageing and cancer susceptibility. | British journal of cancer 20030224 |
| Imbalancing the DNA base excision repair pathway in the mitochondria; targeting and overexpressing N-methylpurine DNA glycosylase in mitochondria leads to enhanced cell killing. | Cancer research 20030201 |
| The recX gene product is involved in the SOS response in Herbaspirillum seropedicae. | Canadian journal of microbiology 20030201 |
| A mechanism of resistance to TRAIL/Apo2L-induced apoptosis of newly established glioma cell line and sensitisation to TRAIL by genotoxic agents. | British journal of cancer 20030127 |
| Telomeric DNA ends are essential for the localization of Ku at telomeres in fission yeast. | The Journal of biological chemistry 20030117 |
| Anesthesia of fish with benzocaine does not interfere with comet assay results. | Mutation research 20030110 |
| Hypersensitivity of DNA polymerase beta null mouse fibroblasts reflects accumulation of cytotoxic repair intermediates from site-specific alkyl DNA lesions. | DNA repair 20030102 |
| Antimutagenic properties of bell and black peppers. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20030101 |
| Repairability during G1 of lesions eliciting sister chromatid exchanges induced by methylmethanesulfonate or ethylmethanesulfonate in bromodeoxyuridine-substituted and unsubstituted DNA strands. | Mutagenesis 20030101 |
| The production of nitric oxide in EL4 lymphoma cells overexpressing growth hormone. | Journal of neuroimmunology 20030101 |
| AtATM is essential for meiosis and the somatic response to DNA damage in plants. | The Plant cell 20030101 |
| The QDE-3 homologue RecQ-2 co-operates with QDE-3 in DNA repair in Neurospora crassa. | Current genetics 20030101 |
| Antimutagenicity of sodium selenite in Chinese hamster V79 cells exposed to azoxymethane, methylmethansulphonate and hydrogen peroxide. | Mutation research 20030101 |
| The yeast ISN1 (YOR155c) gene encodes a new type of IMP-specific 5'-nucleotidase. | BMC biochemistry 20030101 |
| [Biological effect of low doses of alkylating agents in drosophila studies]. | TSitologiia i genetika 20030101 |
| In silico and in vivo analysis reveal a novel gene in Saccharomyces cerevisiae trehalose metabolism. | BMC genomics 20030101 |
| UV- and MMS-induced mutagenesis of lambdaO(am)8 phage under nonpermissive conditions for phage DNA replication. | Acta biochimica Polonica 20030101 |
| ORC and the intra-S-phase checkpoint: a threshold regulates Rad53p activation in S phase. | Genes & development 20021215 |
| ROS1, a repressor of transcriptional gene silencing in Arabidopsis, encodes a DNA glycosylase/lyase. | Cell 20021213 |
| A myogenic differentiation checkpoint activated by genotoxic stress. | Nature genetics 20021201 |
| The flexible loop of human FEN1 endonuclease is required for flap cleavage during DNA replication and repair. | The EMBO journal 20021101 |
| Monomeric yeast PCNA mutants are defective in interacting with and stimulating the ATPase activity of RFC. | Biochemistry 20021029 |
| Characterization of a Schizosaccharomyces pombe strain deleted for a sequence homologue of the human damaged DNA binding 1 (DDB1) gene. | The Journal of biological chemistry 20021025 |
| ATF3 induction following DNA damage is regulated by distinct signaling pathways and over-expression of ATF3 protein suppresses cells growth. | Oncogene 20021024 |
| COP9 signalosome subunits 4 and 5 regulate multiple pleiotropic pathways in Drosophila melanogaster. | Development (Cambridge, England) 20021001 |
| The HMG-CoA reductase inhibitor lovastatin protects cells from the antineoplastic drugs doxorubicin and etoposide. | International journal of molecular medicine 20021001 |
| On the cytotoxicity of some microbial volatile organic compounds as studied in the human lung cell line A549. | Chemosphere 20021001 |
| Severe developmental defects, hypersensitivity to DNA-damaging agents, and lengthened telomeres in Arabidopsis MRE11 mutants. | The Plant cell 20021001 |
| A method for assaying the sensitivity of Drosophila replication checkpoint mutants to anti-cancer and DNA-damaging drugs. | Genome 20021001 |
| A requirement for replication in activation of the ATR-dependent DNA damage checkpoint. | Genes & development 20020915 |
| Inhibitory effect of chamomile essential oil on the sister chromatid exchanges induced by daunorubicin and methyl methanesulfonate in mouse bone marrow. | Toxicology letters 20020905 |
| Interference of papillomavirus E6 protein with single-strand break repair by interaction with XRCC1. | The EMBO journal 20020902 |
| GADD45b and GADD45g are cdc2/cyclinB1 kinase inhibitors with a role in S and G2/M cell cycle checkpoints induced by genotoxic stress. | Journal of cellular physiology 20020901 |
| Suppression of Saccharomyces cerevisiae rad27 null mutant phenotypes by the 5' nuclease domain of Escherichia coli DNA polymerase I. | Current genetics 20020901 |
| The apurinic/apyrimidinic endonuclease activity of Ape1/Ref-1 contributes to human glioma cell resistance to alkylating agents and is elevated by oxidative stress. | Clinical cancer research : an official journal of the American Association for Cancer Research 20020901 |
| Antifertility effects of methylmethane sulphonate on male reproductive organs of wild Indian house rat: histological and histochemical characteristics. | Endocrine regulations 20020901 |
| Radiation- and chemical-induced structural chromosome aberrations in human spermatozoa. | Mutation research 20020725 |
| Inactivation of Mre11 does not affect VSG gene duplication mediated by homologous recombination in Trypanosoma brucei. | The Journal of biological chemistry 20020719 |
| DNA-damage induction of RAD54 can be regulated independently of the RAD9- and DDC1-dependent checkpoints that regulate RNR2. | Current genetics 20020701 |
| Detection of mutation in transgenic CHO cells using green fluorescent protein as a reporter. | Mutation research 20020627 |
| Posttranscriptional regulation of the RAD5 DNA repair gene by the Dun1 kinase and the Pan2-Pan3 poly(A)-nuclease complex contributes to survival of replication blocks. | The Journal of biological chemistry 20020621 |
| Inactivation of homologous recombination suppresses defects in topoisomerase III-deficient mutants. | DNA repair 20020621 |
| Influence of mus201 and mus308 mutations of Drosophila melanogaster on the genotoxicity of model chemicals in somatic cells in vivo measured with the comet assay. | Mutation research 20020619 |
| Diol- and triol-type ginseng saponins potentiate the apoptosis of NIH3T3 cells exposed to methyl methanesulfonate. | Toxicology and applied pharmacology 20020615 |
| Ku is important for telomere maintenance, but not for differential expression of telomeric VSG genes, in African trypanosomes. | The Journal of biological chemistry 20020614 |
| Telomere length deregulation and enhanced sensitivity to genotoxic stress in Arabidopsis mutants deficient in Ku70. | The EMBO journal 20020603 |
| Endogenous DNA abasic sites cause cell death in the absence of Apn1, Apn2 and Rad1/Rad10 in Saccharomyces cerevisiae. | The EMBO journal 20020603 |
| Chemoprotection profiles of sodium thiosulfate on methyl methanesulfonate-induced mutagenesis of bacteriophage T4. | Medical science monitor : international medical journal of experimental and clinical research 20020601 |
| Overlapping roles of the spindle assembly and DNA damage checkpoints in the cell-cycle response to altered chromosomes in Saccharomyces cerevisiae. | Genetics 20020601 |
| Cell signaling in aging and apoptosis. | Mechanisms of ageing and development 20020430 |
| Suppression of a DNA double-strand break repair gene, Ku70, increases radio- and chemosensitivity in a human lung carcinoma cell line. | DNA repair 20020429 |
| Epistatic analysis of the roles of the RAD27 and POL4 gene products in DNA base excision repair in S. cerevisiae. | DNA repair 20020429 |
| Central role for the XRCC1 BRCT I domain in mammalian DNA single-strand break repair. | Molecular and cellular biology 20020401 |
| SN2 DNA-alkylating agent-induced phosphorylation of p53 and activation of p21 gene expression. | Mutation research 20020320 |
| Selective depletion of human DNA-methyltransferase DNMT1 proteins by sulfonate-derived methylating agents. | Cancer research 20020315 |
| In vivo reconstitution of Saccharomyces cerevisiae DNA polymerase epsilon in insect cells. Purification and characterization. | The Journal of biological chemistry 20020308 |
| A comparison of the in vitro Comet assay with the in vitro chromosome aberration assay using whole human blood or Chinese hamster lung cells: validation study using a range of novel pharmaceuticals. | Mutagenesis 20020301 |
| Deficiency in DNA polymerase beta provokes replication-dependent apoptosis via DNA breakage, Bcl-2 decline and caspase-3/9 activation. | Cancer research 20020301 |
| Identification of Ku70 and Ku80 homologues in Arabidopsis thaliana: evidence for a role in the repair of DNA double-strand breaks. | The Plant journal : for cell and molecular biology 20020301 |
| Pnk1, a DNA kinase/phosphatase required for normal response to DNA damage by gamma-radiation or camptothecin in Schizosaccharomyces pombe. | The Journal of biological chemistry 20020208 |
| Reduced fertility and hypersensitivity to mitomycin C characterize Fancg/Xrcc9 null mice. | Human molecular genetics 20020201 |
| Leucine aminopeptidase during meiotic development. | European journal of biochemistry 20020201 |
| Werner and Bloom helicases are involved in DNA repair in a complementary fashion. | Oncogene 20020131 |
| A role for Rad23 proteins in 26S proteasome-dependent protein degradation? | Mutation research 20020129 |
| Implication of p53 in base excision DNA repair: in vivo evidence. | Oncogene 20020124 |
| Structure of spin-labeled methylmethanethiolsulfonate in solution and bound to TEM-1 beta-lactamase determined by electron nuclear double resonance spectroscopy. | Biochemistry 20020122 |
| Complementation between N-terminal Saccharomyces cerevisiae mre11 alleles in DNA repair and telomere length maintenance. | DNA repair 20020122 |
| Application of the single cell gel electrophoresis on yeast cells. | Mutation research 20020115 |
| Evaluation of the genotoxic potential of some microbial volatile organic compounds (MVOC) with the comet assay, the micronucleus assay and the HPRT gene mutation assay. | Mutation research 20020115 |
| Defective flap endonuclease 1 activity in mammalian cells is associated with impaired DNA repair and prolonged S phase delay. | The Journal of biological chemistry 20020104 |
| Inducible protective processes in animal systems. X. Influence of nicotinamide in methyl methanesulfonate-adapted mouse bone marrow cells. | Mutagenesis 20020101 |
| An antisense construct of full-length human RAD50 cDNA confers sensitivity to ionizing radiation and alkylating agents on human cell lines. | Radiation research 20020101 |
| Aging alters the apoptotic response to genotoxic stress. | Nature medicine 20020101 |
| MMS1 protects against replication-dependent DNA damage in Saccharomyces cerevisiae. | Molecular genetics and genomics : MGG 20020101 |
| Distinct functions of BRCA1 and BRCA2 in double-strand break repair. | Breast cancer research : BCR 20020101 |
| Synthesis and activities of bactobolin derivatives having new functionality at C-3. | The Journal of antibiotics 20020101 |
| Genotoxicity of maleic hydrazide, acridine and DEHP in Allium cepa root cells performed by two different laboratories. | Hereditas 20020101 |
| MAP kinase phosphatases. | Genome biology 20020101 |
| Trypanosoma brucei MRE11 is non-essential but influences growth, homologous recombination and DNA double-strand break repair. | Molecular and biochemical parasitology 20020101 |
| Induction of epithelial tumors in Drosophila melanogaster heterozygous for the tumor suppressor gene wts. | Environmental and molecular mutagenesis 20020101 |
| [Functional analysis of yeast homologue gene associated with human DNA helicase causative syndromes]. | Kokuritsu Iyakuhin Shokuhin Eisei Kenkyujo hokoku = Bulletin of National Institute of Health Sciences 20020101 |
| Methyl methanesulfonate. | Report on carcinogens : carcinogen profiles 20020101 |
| Relationship between base excision repair capacity and DNA alkylating agent sensitivity in mouse monocytes. | Mutation research 20011219 |
| Deletion of the MAG1 DNA glycosylase gene suppresses alkylation-induced killing and mutagenesis in yeast cells lacking AP endonucleases. | Mutation research 20011219 |
| Detection of DNA adducts using a quantitative long PCR technique and the fluorogenic 5' nuclease assay (TaqMan). | Mutation research 20011212 |
| Fission yeast Rad50 stimulates sister chromatid recombination and links cohesion with repair. | The EMBO journal 20011203 |
| The protein kinase PKB/Akt regulates cell survival and apoptosis by inhibiting Bax conformational change. | Oncogene 20011122 |
| On the nature of conformational openings: native and unfolded-state hydrogen and thiol-disulfide exchange studies of ferric aquomyoglobin. | Journal of molecular biology 20011116 |
| Hyperactivation of the yeast DNA damage checkpoint by TEL1 and DDC2 overexpression. | The EMBO journal 20011115 |
| The structure-specific endonuclease Ercc1-Xpf is required for targeted gene replacement in embryonic stem cells. | The EMBO journal 20011115 |
| The participation of AtXPB1, the XPB/RAD25 homologue gene from Arabidopsis thaliana, in DNA repair and plant development. | The Plant journal : for cell and molecular biology 20011101 |
| Role of the DNA repair nucleases Rad13, Rad2 and Uve1 of Schizosaccharomyces pombe in mismatch correction. | Journal of molecular biology 20011019 |
| Differential activation of mitogen-activated protein kinases by methyl methanesulfonate in the kidney of young and old rats. | Mutation research 20011018 |
| Genotoxic effects of copper sulphate in freshwater planarian in vivo, studied with the single-cell gel test (comet assay). | Mutation research 20011018 |
| Investigation of genotoxic and antigenotoxic activities of chlorophylls and chlorophyllin in cultured V79 cells. | Mutation research 20011018 |
| Age-specific changes in expression, activity, and activation of the c-Jun NH(2)-terminal kinase and p38 mitogen-activated protein kinases by methyl methanesulfonate in rats. | Mechanisms of ageing and development 20011001 |
| Antimutagenic effects of the mushroom Agaricus blazei Murrill extracts on V79 cells. | Mutation research 20010920 |
| TATA binding protein-associated CK2 transduces DNA damage signals to the RNA polymerase III transcriptional machinery. | Cell 20010907 |
| DNA alkylation-induced phosphorylation of p53 and activation of kinases in colon cancer cells. | International journal of oncology 20010901 |
| Contribution of E. coli AlkA, TagA glycosylases and UvrABC-excinuclease in MMS mutagenesis. | Mutation research 20010901 |
| In vivo consequences of putative active site mutations in yeast DNA polymerases alpha, epsilon, delta, and zeta. | Genetics 20010901 |
| Multiple interactions among the components of the recombinational DNA repair system in Schizosaccharomyces pombe. | Genetics 20010901 |
| Bipartite binding of a kinase activator activates Cdc7-related kinase essential for S phase. | The Journal of biological chemistry 20010817 |
| Transcriptional regulation of the human DNA polymerase delta catalytic subunit gene POLD1 by p53 tumor suppressor and Sp1. | The Journal of biological chemistry 20010810 |
| Regulation of DNA replication fork progression through damaged DNA by the Mec1/Rad53 checkpoint. | Nature 20010802 |
| The DNA helicase activity of yeast Sgs1p is essential for normal lifespan but not for resistance to topoisomerase inhibitors. | Mechanisms of ageing and development 20010801 |
| Synergism between base excision repair, mediated by the DNA glycosylases Ntg1 and Ntg2, and nucleotide excision repair in the removal of oxidatively damaged DNA bases in Saccharomyces cerevisiae. | Molecular genetics and genomics : MGG 20010801 |
| On the role of alkylating mechanisms, O-alkylation and DNA-repair in genotoxicity and mutagenicity of alkylating methanesulfonates of widely varying structures in bacterial systems. | Chemico-biological interactions 20010731 |
| Identification of genotoxic stress in human cells by fluorescent monitoring of p53 expression. | Mutation research 20010725 |
| Overexpression of type I topoisomerases sensitizes yeast cells to DNA damage. | The Journal of biological chemistry 20010713 |
| Photoaffinity labeling of mouse fibroblast enzymes by a base excision repair intermediate. Evidence for the role of poly(ADP-ribose) polymerase-1 in DNA repair. | The Journal of biological chemistry 20010706 |
| Genetic damage by bifunctional agents in repair-active pre-meiotic stages of Drosophila males. | Mutation research 20010701 |
| Micronuclei and other nuclear lesions as genotoxicity indicators in rainbow trout Oncorhynchus mykiss. | Ecotoxicology and environmental safety 20010701 |
| The effect of methyl methanesulfonate (MMS)-induced excision repair on p53-dependent apoptosis in human lymphoid cells. | Research communications in molecular pathology and pharmacology 20010701 |
| The N-terminal region of Sgs1, which interacts with Top3, is required for complementation of MMS sensitivity and suppression of hyper-recombination in sgs1 disruptants. | Molecular genetics and genomics : MGG 20010701 |
| A comparison of intraperitoneal and oral gavage administration in comet assay in mouse eight organs. | Mutation research 20010627 |
| DNA damage and repair in Arabidopsis thaliana as measured by the comet assay after treatment with different classes of genotoxins. | Mutation research 20010627 |
| A novel protein interacts with the Werner's syndrome gene product physically and functionally. | The Journal of biological chemistry 20010608 |
| The death substrate Gas2 binds m-calpain and increases susceptibility to p53-dependent apoptosis. | The EMBO journal 20010601 |
| Induction of the SAPK activator MIG-6 by the alkylating agent methyl methanesulfonate. | Molecular carcinogenesis 20010601 |
| Disruptions of the Ustilago maydis REC2 gene identify a protein domain important in directing recombinational repair of DNA. | Molecular microbiology 20010601 |
| Structural and functional characterization of the recR gene of Streptomyces. | Molecular genetics and genomics : MGG 20010601 |
| The essential HupB and HupN proteins of Pseudomonas putida provide redundant and nonspecific DNA-bending functions. | The Journal of biological chemistry 20010518 |
| RasG regulates discoidin gene expression during Dictyostelium growth. | Experimental cell research 20010515 |
| Transcription factors Oct-1 and NF-YA regulate the p53-independent induction of the GADD45 following DNA damage. | Oncogene 20010510 |
| Increased DNA double strand breakage is responsible for sensitivity of the pso3-1 mutant of Saccharomyces cerevisiae to hydrogen peroxide. | Mutation research 20010510 |
| Phenotypes of Drosophila homologs of human XPF and XPG to chemically-induced DNA modifications. | Mutation research 20010509 |
| DNA damaging agents increase gadd153 (CHOP-10) messenger RNA levels in bovine preimplantation embryos cultured in vitro. | Biology of reproduction 20010501 |
| Effect of ultraviolet light, methyl methanesulfonate and ionizing radiation on the genotoxic response and apoptosis of mouse fibroblasts lacking c-Fos, p53 or both. | Mutagenesis 20010501 |
| Repression of GADD153/CHOP by NF-kappaB: a possible cellular defense against endoplasmic reticulum stress-induced cell death. | Oncogene 20010419 |
| Roles of yeast DNA polymerases delta and zeta and of Rev1 in the bypass of abasic sites. | Genes & development 20010415 |
| Rad54 protein stimulates heteroduplex DNA formation in the synaptic phase of DNA strand exchange via specific interactions with the presynaptic Rad51 nucleoprotein filament. | Journal of molecular biology 20010413 |
| Isolation and genetic characterisation of the Drosophila homologue of (SCE)REV3, encoding the catalytic subunit of DNA polymerase zeta. | Mutation research 20010404 |
| Mitogen-activated protein kinase phosphatase is required for genotoxic stress relief in Arabidopsis. | Genes & development 20010315 |
| Factors that control the reactivity of the interface cysteine of triosephosphate isomerase from Trypanosoma brucei and Trypanosoma cruzi. | Biochemistry 20010313 |
| Detection of DNA primary damage by premature chromosome condensation in human peripheral blood lymphocytes treated with methyl methanesulfonate. | Mutagenesis 20010301 |
| Activation of Ty transposition by mutagens. | Mutation research 20010301 |
| Overexpression of endonuclease III protects Escherichia coli mutants defective in alkylation repair against lethal effects of methylmethanesulphonate. | FEBS letters 20010223 |
| Cell cycle-dependent and DNA damage-inducible nuclear localization of FEN-1 nuclease is consistent with its dual functions in DNA replication and repair. | The Journal of biological chemistry 20010216 |
| Downregulation of MDM2 stabilizes p53 by inhibiting p53 ubiquitination in response to specific alkylating agents. | FEBS letters 20010216 |
| Alkylating agent and chromatin structure determine sequence context-dependent formation of alkylpurines. | Journal of molecular biology 20010216 |
| Evidence in Escherichia coli that N3-methyladenine lesions induced by a minor groove binding methyl sulfonate ester can be processed by both base and nucleotide excision repair. | Biochemistry 20010213 |
| Tof1p regulates DNA damage responses during S phase in Saccharomyces cerevisiae. | Genetics 20010201 |
| Novel quantitative assays for estimating the antimicrobial activity of fresh garlic juice. | Journal of food protection 20010201 |
| DNA damage leads to a Cyclin A-dependent delay in metaphase-anaphase transition in the Drosophila gastrula. | Current biology : CB 20010109 |
| Transcriptional regulation and function during the human cell cycle. | Nature genetics 20010101 |
| Antimutagenic activity of fluphenazine in short-term tests. | Mutagenesis 20010101 |
| Disruption of the Arabidopsis RAD50 gene leads to plant sterility and MMS sensitivity. | The Plant journal : for cell and molecular biology 20010101 |
| Involvement of SGS1 in DNA damage-induced heteroallelic recombination that requires RAD52 in Saccharomyces cerevisiae. | Molecular & general genetics : MGG 20010101 |
| An Aspergillus nidulans uvsC null mutant is deficient in homologous DNA integration. | Molecular & general genetics : MGG 20010101 |
| BRCA1 and BRCA2 protein expressions in an ovotestis of a 46, XX true hermaphrodite. | Breast cancer research : BCR 20010101 |
| Feeding thiol-containing compounds, derived from vegetables, fails to inhibit N-methylnitrosourea-induced mammary tumorigenesis. | Cancer detection and prevention 20010101 |
| Mammalian DNA beta-polymerase in base excision repair of alkylation damage. | Progress in nucleic acid research and molecular biology 20010101 |
| BRCA2 and homologous recombination. | Breast cancer research : BCR 20010101 |
| Detection of alkylation damage in human lymphocyte DNA with the comet assay. | Acta biochimica Polonica 20010101 |
| A role for Saccharomyces cerevisiae histone H2A in DNA repair. | Nature 20001201 |
| Relative importance of transport and alkylation for pancreatic beta-cell toxicity of streptozotocin. | Diabetologia 20001201 |
| LCD1: an essential gene involved in checkpoint control and regulation of the MEC1 signalling pathway in Saccharomyces cerevisiae. | The EMBO journal 20001101 |
| Upregulation of CHOP-10 (gadd153) expression in the mouse blastocyst as a response to stress. | Molecular reproduction and development 19991201 |
| Cadmium induces conformational modifications of wild-type p53 and suppresses p53 response to DNA damage in cultured cells. | The Journal of biological chemistry 19991029 |
| Different populations of progesterone receptor-steroid complexes in binding to specific DNA sequences: effects of salts on kinetics and specificity. | The Journal of steroid biochemistry and molecular biology 19981101 |
| Conformational change in human DNA repair enzyme O6-methylguanine-DNA methyltransferase upon alkylation of its active site by SN1 (indirect-acting) and SN2 (direct-acting) alkylating agents: breaking a 'salt-link'. | Biochemistry 19960924 |
| Role of cysteines 640, 656, and 661 in steroid binding to rat glucocorticoid receptors. | The Journal of biological chemistry 19920605 |
| Localization of the vicinal dithiols involved in steroid binding to the rat glucocorticoid receptor. | Endocrinology 19901101 |
| Differential mutant quantitation at the mouse lymphoma tk and CHO hgprt loci. | Mutagenesis 19890901 |
| Dominant lethal assay in female mice after oral dosing with dichlorvos or exposure to atmospheres containing dichlorovos. | Mutation research 19760101 |