Home Nitriles Malononitrile

Malononitrile

CAS No.:
109-77-3
Catalog Number:
AG003RFK
Molecular Formula:
C3H2N2
Molecular Weight:
66.0614
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1g
95%
In Stock USA
United States
$25
- +
5g
99%(GC)
In Stock USA
United States
$57
- +
25g
99%(GC)
In Stock USA
United States
$94
- +
Product Description
Catalog Number:
AG003RFK
Chemical Name:
Malononitrile
CAS Number:
109-77-3
Molecular Formula:
C3H2N2
Molecular Weight:
66.0614
MDL Number:
MFCD00001883
IUPAC Name:
propanedinitrile
InChI:
InChI=1S/C3H2N2/c4-2-1-3-5/h1H2
InChI Key:
CUONGYYJJVDODC-UHFFFAOYSA-N
SMILES:
N#CCC#N
EC Number:
203-703-2
UNII:
EBL1KKS93J
NSC Number:
3769
RTECS Number:
OO3150000
UN Number:
2647
Properties
Complexity:
82.6  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
66.022g/mol
Formal Charge:
0
Heavy Atom Count:
5  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
66.063g/mol
Monoisotopic Mass:
66.022g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
47.6A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-0.5  
Literature
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Synthesis and vasodilation activity of some novel bis(3-pyridinecarbonitrile) derivatives. European journal of medicinal chemistry 20101101
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Ethyl 6-amino-5-cyano-2,4-bis-(4-methyl-phen-yl)-4H-pyran-3-carboxyl-ate. Acta crystallographica. Section E, Structure reports online 20101001
2,6-Dichloro-pyridine-3,5-dicarbonitrile. Acta crystallographica. Section E, Structure reports online 20101001
Highly enantioselective Michael addition of malononitrile to vinylogous imine intermediates generated in situ from arylsulfonyl indoles. Chemistry (Weinheim an der Bergstrasse, Germany) 20100924
Platinum-catalyzed cross-dehydrogenative coupling reaction in the absence of oxidant. Organic & biomolecular chemistry 20100921
Green one pot solvent-free synthesis of pyrano[2,3-c]-pyrazoles and pyrazolo[1,5-a]pyrimidines. Molecules (Basel, Switzerland) 20100920
InCl3 mediated one-pot multicomponent synthesis, anti-microbial, antioxidant and anticancer evaluation of 3-pyranyl indole derivatives. Bioorganic & medicinal chemistry letters 20100901
Synthesis of polysubstituted dihydropyridines by four-component reactions of aromatic aldehydes, malononitrile, arylamines, and acetylenedicarboxylate. Organic letters 20100820
L-Histidine and L-arginine promote Knoevenagel reaction in water. Amino acids 20100801
An efficient, multicomponent approach for solvent-free synthesis of 2-amino-4H-chromene scaffold. Molecular diversity 20100801
One-pot synthesis of 4,6-diaryl-2-oxo(imino)-1,2-dihydropyridine-3-carbonitrile; a New Scaffold for p38alpha MAP kinase inhibition. Journal of combinatorial chemistry 20100712
Three-component synthesis of 2-oxoindolin-3-ylphosphonates. Chemical & pharmaceutical bulletin 20100701
2-(2,3,4,9-Tetra-hydro-1H-carbazol-1-ylidene)propane-dinitrile. Acta crystallographica. Section E, Structure reports online 20100701
6-(4-Amino-phen-yl)-2-eth-oxy-4-(2-thien-yl)nicotinonitrile. Acta crystallographica. Section E, Structure reports online 20100701
Efficient one-pot synthesis of substituted pyridines through multicomponent reaction. Organic & biomolecular chemistry 20100628
Concise copper-catalyzed one-pot tandem synthesis of benzimidazo[1,2-b]isoquinolin-11-one derivatives. Chemical communications (Cambridge, England) 20100621
Photoelectron imaging of NCCCN(-): The triplet ground state and the singlet-triplet splitting of dicyanocarbene. The Journal of chemical physics 20100614
A convenient strategy for the annulation of aryl scaffold to A/B-ring steroids under microwave irradiation. Steroids 20100601
Selective one-pot multicomponent synthesis and anti-tubercular evaluation of 5-(aryl/cyclohexylsulfanyl)-2-alkoxy-4,6-diarylnicotinonitriles. Bioorganic & medicinal chemistry letters 20100601
Designing Tetrahydroimidazo[1,2-a]pyridine derivatives via catalyst-free Aza-Diels-Alder reaction (ADAR) and their insecticidal evaluation. Journal of agricultural and food chemistry 20100526
A convenient one-pot synthesis of 3-amino-2, 5-dihydropyridazine and pyrimidine derivatives in the presence of high surface area MgO as a highly effective heterogeneous base catalyst. Molecular diversity 20100501
Novel DNA intercalators without basic side chains as efficient antitumor agents: design, synthesis and evaluation of benzo-[c,d]-indol-malononitrile derivatives. Bioorganic & medicinal chemistry 20100501
Ethyl 2-(6-amino-5-cyano-3,4-dimethyl-2H,4H-pyrano[2,3-c]pyrazol-4-yl)acetate. Acta crystallographica. Section E, Structure reports online 20100501
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6-(4-Bromo-phen-yl)-2-eth-oxy-4-(2,4,5-trimethoxy-phen-yl)nicotinonitrile. Acta crystallographica. Section E, Structure reports online 20100301
Microwave-assisted and efficient solvent-free knoevenagel condensation. A sustainable protocol using porous calcium hydroxyapatite as catalyst. Molecules (Basel, Switzerland) 20100204
Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. European journal of medicinal chemistry 20100201
Practical and efficient synthesis of pyrano[3,2-c]pyridone, pyrano[4,3-b]pyran and their hybrids with nucleoside as potential antiviral and antileishmanial agents. Bioorganic & medicinal chemistry letters 20100201
Cytotoxicity and reversal of multidrug resistance by tryptanthrin-derived indoloquinazolines. Acta pharmacologica Sinica 20100201
Ethyl 2-amino-7,7-dimethyl-2',5-dioxo-spiro-[5,6,7,8-tetra-hydro-4H-chromene-4,3'(2'H)-1H-indole]-3-carboxyl-ate. Acta crystallographica. Section E, Structure reports online 20100201
Bifunctional acid-base ionic liquid organocatalysts with a controlled distance between acid and base sites. Chemistry (Weinheim an der Bergstrasse, Germany) 20100125
Mechanistic investigation of the dipolar [2+2] cycloaddition-cycloreversion reaction between 4-(N,N-dimethylamino)phenylacetylene and arylated 1,1-dicyanovinyl derivatives to form intramolecular charge-transfer chromophores. Chemistry (Weinheim an der Bergstrasse, Germany) 20100104
Ultrasound-assisted one-pot, three-component synthesis of 1H-pyrazolo[1,2-b]phthalazine-5,10-diones. Ultrasonics sonochemistry 20100101
Discovery of colon tumor cell growth inhibitory agents through a combinatorial approach. European journal of medicinal chemistry 20100101
Diversity synthesis of N-substituted 2-amino-1,6-naphthyridine derivatives under microwave irradiation. Journal of combinatorial chemistry 20100101
Synthesis and property of solvatochromic fluorophore based on D-pi-A molecular system: 2-[[3-cyano-4-(N-ethyl-N-(2-hydroxyethyl)amino)styryl]-5,5-dimethylfuran-2(5H)-ylidene]malononitrile dye. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20100101
Silica gel-catalyzed one-pot syntheses in water and fluorescence properties studies of 5-amino-2-aryl-3H-chromeno[4,3,2-de][1,6]naphthyridine-4-carbonitriles and 5-amino-2-aryl-3H-quinolino[4,3,2-de][1,6]naphthyridine-4-carbonitriles. Journal of combinatorial chemistry 20100101
Novel 6,8-dibromo-4(3H)-quinazolinone derivatives of promising anti-inflammatory and analgesic properties. Acta poloniae pharmaceutica 20100101
A new and facile synthetic approach to substituted 2-thioxoquinazolin-4-ones by the annulation of a pyrimidine derivative. Beilstein journal of organic chemistry 20100101
2-[2-(4-Nitro-phenyl)hy-dra-zin-yl-idene]malononitrile. Acta crystallographica. Section E, Structure reports online 20100101
Ethyl 6'-amino-5'-cyano-2'-methyl-2-oxospiro-[indoline-3,4'-pyran]-3'-carboxyl-ate. Acta crystallographica. Section E, Structure reports online 20100101
Quinoxaline-2-carbonitrile. Acta crystallographica. Section E, Structure reports online 20100101
6-(4-Bromo-phen-yl)-2-eth-oxy-4-(4-ethoxy-phen-yl)nicotinonitrile. Acta crystallographica. Section E, Structure reports online 20100101
Current Challenges for the Early Detection of Alzheimer's Disease: Brain Imaging and CSF Studies. Journal of clinical neurology (Seoul, Korea) 20091201
2-(1-Propyl-2,6-distyryl-1,4-dihydro-pyridin-4-yl-idene)malononitrile. Acta crystallographica. Section E, Structure reports online 20091201
A reinvestigation of the acid-promoted heterocyclization of 2-(2-oxo-2-arylethyl)malononitriles in the presence of amines. Molecular diversity 20091101
An efficient protocol for the synthesis of 2-amino-4,6-diphenylpyridine-3-carbonitrile using ionic liquid ethylammonium nitrate. Molecular diversity 20091101
Synthesis of some novel pyrazolo[3,4-b]pyridine and pyrazolo[3,4-d]pyrimidine derivatives bearing 5,6-diphenyl-1,2,4-triazine moiety as potential antimicrobial agents. European journal of medicinal chemistry 20091101
6-Amino-8-(2-bromo-phen-yl)-1,7,8,8a-tetrahydro-3H-isothio-chromene-5,7,7-tricarbonitrile dimethyl-formamide solvate. Acta crystallographica. Section E, Structure reports online 20091101
Ethyl 6-amino-5-cyano-2-methyl-4-propyl-4H-pyran-3-carboxyl-ate. Acta crystallographica. Section E, Structure reports online 20091101
5-Amino-7-(4-bromo-phen-yl)indane-4,6-dicarbonitrile. Acta crystallographica. Section E, Structure reports online 20091101
6-(4-Bromo-phen-yl)-2-eth-oxy-4-(2,4,6-trimethoxy-phen-yl)nicotinonitrile. Acta crystallographica. Section E, Structure reports online 20091101
Truxene-based columnar liquid crystals: self-assembled structures and electro-active properties. Chemistry, an Asian journal 20091005
Green chemoselective synthesis of thiazolo[3,2-a]pyridine derivatives and evaluation of their antioxidant and cytotoxic activities. Bioorganic & medicinal chemistry letters 20091001
Exploring catalyst and solvent effects in the multicomponent synthesis of pyridine-3,5-dicarbonitriles. The Journal of organic chemistry 20090918
Acute toxicity of some synthetic cyanogens in rats and their response to oral treatment with alpha-ketoglutarate. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20090901
1-Meth-oxy-3-o-tolyl-bicyclo-[2.2.2]oct-5-ene-2,2-dicarbonitrile. Acta crystallographica. Section E, Structure reports online 20090901
Enantioselective Michael addition of malononitrile to chalcones catalyzed by a simple quinine-Al(O(i)Pr)(3) complex: a simple method for the synthesis of a chiral 4H-pyran derivative. Chemical communications (Cambridge, England) 20090821
Computational investigation of rearrangements in huisgen cycloadducts of azolium N-dicyanomethanide 1,3-dipoles with alkynes: a mechanistic panoply. The Journal of organic chemistry 20090807
2-[2-Benzoyl-3,3-bis-(methyl-sulfan-yl)prop-2-enyl-idene]malononitrile. Acta crystallographica. Section E, Structure reports online 20090801
2-[(2,3,6,7-Tetra-hydro-1H,5H-benzo[ij]quinolizin-9-yl)methyl-ene]propane-dinitrile. Acta crystallographica. Section E, Structure reports online 20090701
2-(1,2,3,4-Tetra-hydro-phenanthren-1-yl-idene)malononitrile. Acta crystallographica. Section E, Structure reports online 20090701
Efficient three-component one-pot synthesis of fully substituted pyridin-2(1H)-ones via tandem Knoevenagel condensation-ring-opening of cyclopropane-intramolecular cyclization. Chemical communications (Cambridge, England) 20090628
Synthesis of certain pyrrole derivatives as antimicrobial agents. Acta pharmaceutica (Zagreb, Croatia) 20090601
Synthesis and immunomodulation of human lymphocyte proliferation and cytokine (interferon-gamma) production of four novel malonitrilamides. Chemical biology & drug design 20090601
2-(4-{3-[1-(3-Bromo-prop-yl)-3,3-dimethyl-2,3-dihydro-1H-indol-2-yl-idene]prop-1-en-yl}-3-cyano-5,5-dimethyl-2,5-dihydro-furan-2-yl-idene)malononitrile. Acta crystallographica. Section E, Structure reports online 20090601
4-(4-Fluoro-phen-yl)-2-oxo-1,2,5,6-tetra-hydro-benzo[h]quinoline-3-carbonitrile. Acta crystallographica. Section E, Structure reports online 20090601
Investigation of catalytic characterization of two-dimensional molecular space with regular ammonium and pyridine groups. Langmuir : the ACS journal of surfaces and colloids 20090519
Synthesis of dihydrothiophenes or spirocyclic compounds by domino reactions of 1,3-thiazolidinedione. The Journal of organic chemistry 20090501
Photophysical study of blue, green, and orange-red light-emitting carbazoles (1). The Journal of organic chemistry 20090501
2-Amino-4-[1-(2-chloro-phen-yl)-5-methyl-1H-1,2,3-triazol-4-yl]-6-(4-methyl-phen-yl)benzene-1,3-dicarbonitrile. Acta crystallographica. Section E, Structure reports online 20090501
(E,E)-2-[3,4-Bis(4-methyl-benzyl-idene)-5-oxotetra-hydro-furan-2-yl-idene]propane-dinitrile. Acta crystallographica. Section E, Structure reports online 20090401
2'-Amino-1'-(4-chloro-phen-yl)-1,7',7'-trimethyl-2,5'-dioxo-5',6',7',8'-tetra-hydrospiro-[indoline-3,4'(1'H)-quinoline]-3'-carbonitrile dimethyl-formamide solvate dihydrate. Acta crystallographica. Section E, Structure reports online 20090401
Stimulatory effect of benzylidenemalononitrile tyrphostins on expression of NO-dependent genes in U-937 monocytic cells. European journal of pharmacology 20090315
2-(3-Chloro-1,2-dihydro-pyrazin-2-yl-idene)malononitrile. Acta crystallographica. Section E, Structure reports online 20090301
Electrocatalytic multicomponent assembling of isatins, 3-methyl-2-pyrazolin-5-ones and malononitrile: facile and convenient way to functionalized spirocyclic [indole-3,4'-pyrano[2,3-c]pyrazole] system. Molecular diversity 20090201
Ionic liquid promoted preparation of 4H-thiopyran and pyrimidine nucleoside-thiopyran hybrids through one-pot multi-component reaction of thioamide. Molecular diversity 20090201
3,3,6,6,9,9-Hexamethyl-2,3,4,5,6,7,8,9-octa-hydro-1H-xanthene-1,8-dione. Acta crystallographica. Section E, Structure reports online 20090201
Mechanochemical solvent-free and catalyst-free one-pot synthesis of pyrano[2,3-d]pyrimidine-2,4(1H,3H)-diones with quantitative yields. Molecules (Basel, Switzerland) 20090119
One-step synthesis of pyrido[1,2-a]benzimidazole derivatives by a novel multicomponent reaction of chloroacetonitrile, malononitrile, aromatic aldehyde, and pyridine. The Journal of organic chemistry 20090116
Selective benzylic and allylic alkylation of protic nucleophiles with sulfonamides through double Lewis acid catalyzed cleavage of sp3 carbon-nitrogen bonds. Chemistry (Weinheim an der Bergstrasse, Germany) 20090101
Inorganic zinc salts catalyzed Knoevenagel condensation at room temperature without solvent. Preparative biochemistry & biotechnology 20090101
Synthesis of novel tetrahydronaphthalen-2-yl heterocycles for analgesic, anti-inflammatory and antipyretic evaluation. Acta poloniae pharmaceutica 20090101
New convenient four-component synthesis of 6-amino-2,4-dihydropyrano[2,3-c]pyrazol-5-carbonitriles and one-pot synthesis of 6'-aminospiro[(3H)-indol-3,4'-pyrano[2,3-c]pyrazol]-(1H)-2-on-5'-carbonitriles. Journal of combinatorial chemistry 20090101
Novel one-pot three- and pseudo-five-component reactions: synthesis of functionalized benzo[g]- and dihydropyrano[2,3-g]chromene derivatives. Journal of combinatorial chemistry 20090101
Novel 3-(p-substituted phenyl)-6-bromo-4(3H)-quinazolinone derivatives of promising antiinflammatory and analgesic properties. Acta poloniae pharmaceutica 20090101
Hydroxyapatite supported caesium carbonate as a new recyclable solid base catalyst for the Knoevenagel condensation in water. Beilstein journal of organic chemistry 20090101
Enaminones as building blocks in heterocyclic syntheses: reinvestigating the product structures of enaminones with malononitrile. A novel route to 6-substituted-3-oxo-2,3-dihydropyridazine-4-carboxylic acids. Molecules (Basel, Switzerland) 20081229
Photoinduced tandem three-component coupling of propanedinitrile, 2,5-dimethylhexa-2,4-diene, and cyanoarenes. The Journal of organic chemistry 20081107
A convenient three-component reaction leading to the synthesis of polysubstituted cyclohexene derivatives. Organic & biomolecular chemistry 20081007
2-{3-Cyano-5,5-dimethyl-4-[6-(pyrrol-i-din-1-yl)hexa-1,3,5-trien-yl]-2,5-dihydro-2-furylidene}malononitrile. Acta crystallographica. Section E, Structure reports online 20081001
The effect of 5-alkyl modification on the biological activity of pyrrolo[2,3-d]pyrimidine containing classical and nonclassical antifolates as inhibitors of dihydrofolate reductase and as antitumor and/or antiopportunistic infection agents. Journal of medicinal chemistry 20080814
6-Amino-4-(4-chloro-phen-yl)-2-oxo-1,2-dihydro-pyridine-3,5-dicarbonitrile ethanol solvate. Acta crystallographica. Section E, Structure reports online 20080801
Synthesis and antimicrobial activity of some new pyrazole, fused pyrazolo[3,4-d]-pyrimidine and pyrazolo[4,3-e][1,2,4]-triazolo[1,5-c]pyrimidine derivatives. Molecules (Basel, Switzerland) 20080729
Photochemical monoalkylation of propanedinitrile by electron-rich alkenes. Organic letters 20080703
Anti-inflammatory and analgesic activities of some newly synthesized pyridinedicarbonitrile and benzopyranopyridine derivatives. Acta pharmaceutica (Zagreb, Croatia) 20080601
4-(1H-Benzimidazol-2-yl)benzonitrile. Acta crystallographica. Section E, Structure reports online 20080601
Dimethyl 2-(methyl-amino-methyl-ene)malonate. Acta crystallographica. Section E, Structure reports online 20080601
2-Amino-4'-bromo-2',5-dioxo-4H,5H-pyrano[3,2-c]chromene-4-spiro-3'(2'H)-1'H-indole-3-carbonitrile N,N-dimethyl-formamide solvate. Acta crystallographica. Section E, Structure reports online 20080601
Dimethyl 2-(amino-methyl-ene)malonate. Acta crystallographica. Section E, Structure reports online 20080601
An efficient and facile synthesis of highly substituted 2,6-dicyanoanilines. The Journal of organic chemistry 20080502
Diammonium hydrogen phosphate as a versatile and efficient catalyst for the one-pot synthesis of pyrano[2,3-d]pyrimidinone derivatives in aqueous media. Molecular diversity 20080501
2-Amino-4-(4-chloro-phen-yl)-6-ferro-cenylpyridine-3-carbonitrile. Acta crystallographica. Section E, Structure reports online 20080501
2-[(5-Amino-3-methyl-1-phenyl-1H-pyrazol-4-yl)(4-chloro-phen-yl)meth-yl]malononitrile. Acta crystallographica. Section E, Structure reports online 20080501
Reduced band gap dithieno[3,2-b:2',3'-d]pyrroles: new n-type organic materials via unexpected reactivity. Organic letters 20080417
6-Amino-3-methyl-4-(4-nitro-phen-yl)-1-phenyl-pyrazolo[3,4-b]pyridine-5-carbonitrile. Acta crystallographica. Section E, Structure reports online 20080401
6-Amino-1-benzyl-4-(4-chloro-phen-yl)-3-(4-pyrid-yl)-1,4-dihydro-pyrano[2,3-c]pyrazole-5-carbonitrile. Acta crystallographica. Section E, Structure reports online 20080401
One-step synthesis of polysubstituted benzene derivatives by multi-component cyclization of alpha-bromoacetate, malononitrile and aromatic aldehydes. Chemical communications (Cambridge, England) 20080328
temperature-dependent orientational dynamics of 1,n-dicyano n-alkanes. The journal of physical chemistry. B 20080313
The condensation of salicylaldehydes and malononitrile revisited: synthesis of new dimeric chromene derivatives. The Journal of organic chemistry 20080307
2-[2-(4-Methyl-benzo-yl)-3,3-bis-(methyl-sulfan-yl)prop-2-enyl-idene]malononitrile. Acta crystallographica. Section E, Structure reports online 20080301
Novel three-component synthesis and antiproliferative properties of diversely functionalized pyrrolines. Bioorganic & medicinal chemistry letters 20080215
2-{3-Cyano-5,5-dimethyl-4-[4-(piperidin-1-yl)buta-1,3-dien-yl]-2,5-dihydro-furan-2-yl-idene}malononitrile. Acta crystallographica. Section E, Structure reports online 20080201
1,2-Bis[5-(2,2'-dicyano-vinyl)-2-n-pentyl-3-thien-yl]-3,3,4,4,5,5-hexa-fluoro-cyclo-pent-1-ene: a new photochromic diaryl-ethene compound. Acta crystallographica. Section E, Structure reports online 20080201
Highly enantioselective Michael addition of malononitrile to alpha,beta-unsaturated ketones. Organic & biomolecular chemistry 20080121
Reaction of 1-tert-butyl-3,4-diphenyl-1,2,4-triazol-5-ylidenes with a malonic ester. Organic & biomolecular chemistry 20080107
2-Amino-4-(4-bromo-phen-yl)-6-ferro-cenyl-pyridine-3-carbonitrile. Acta crystallographica. Section E, Structure reports online 20080101
6'-Amino-3'-methyl-2-oxo-1'-phenyl-1',3a',4',7a'-tetra-hydrospiro-[1H-indole-3(2H),4'-pyrano[2,3-d]pyrazole]-5'-carbonitrile. Acta crystallographica. Section E, Structure reports online 20080101
[(2-Phenylindol-3-yl)methylene]propanedinitriles inhibit the growth of breast cancer cells by cell cycle arrest in G(2)/M phase and apoptosis. Bioorganic & medicinal chemistry 20071201
An atom efficient, solvent-free, green synthesis and antimycobacterial evaluation of 2-amino-6-methyl-4-aryl-8-[(E)-arylmethylidene]-5,6,7,8-tetrahydro-4H-pyrano[3,2-c]pyridine-3-carbonitriles. Bioorganic & medicinal chemistry letters 20071201
SmCl3-catalyzed C-acylation of 1,3-dicarbonyl compounds and malononitrile. Organic letters 20071025
Synthesis of C2-symmetric bisamidines: a new type of chiral metal-free Lewis acid analogue interacting with carbonyl groups. The Journal of organic chemistry 20070720
Antiproliferative and apoptosis inducing properties of pyrano[3,2-c]pyridones accessible by a one-step multicomponent synthesis. Bioorganic & medicinal chemistry letters 20070715
Efficient method for the synthesis of polysubstituted benzenes by one-pot tandem reaction of vinyl malononitriles with nitroolefins. The Journal of organic chemistry 20070706
Theoretical study on the ground and excited states of dicyanocarbene (C3N2) and its isomers: a low-temperature matrix emission spectrum attributable to 3-cyano-2H-azirenylidene. The journal of physical chemistry. A 20070607
One-step synthesis of heterocyclic privileged medicinal scaffolds by a multicomponent reaction of malononitrile with aldehydes and thiols. The Journal of organic chemistry 20070427
An improved procedure for the three-component synthesis of highly substituted pyridines using ionic liquid. The Journal of organic chemistry 20070413
Novel synthesis of [1]-benzothiepino[5,4-b]pyridine-3-carbonitriles and their anti-inflammatory properties. Bioorganic & medicinal chemistry 20070315
An efficient synthesis of pyrazolo[3,4-b]quinolin-3-amine and benzo[b][1,8]naphthyridine derivatives. Molecules (Basel, Switzerland) 20070308
Molecular diodes and ultra-thin organic rectifying junctions: Au-S-CnH2n-Q3CNQ and TCNQ derivatives. Physical chemistry chemical physics : PCCP 20070227
Vibrational fingerprint of the structural tuning in push-pull organic chromophores with quinoid or proaromatic spacers. The Journal of chemical physics 20070221
Michael additions of methylene active compounds to chalcone in ionic liquids without any catalyst: the peculiar properties of ionic liquids. Chemistry (Weinheim an der Bergstrasse, Germany) 20070101
2-Arylhydrazononitriles as building blocks in heterocyclic synthesis: A novel route to 2-substituted-1,2,3-triazoles and 1,2,3-triazolo[4,5-b]pyridines. Beilstein journal of organic chemistry 20070101
Radical reactions of [60]fullerene mediated by manganese(III) acetate dihydrate. Journal of nanoscience and nanotechnology 20070101
Hydrogen sulfide, nitric oxide and a molecular mass 66 u substance in the exhaled breath of chronic pancreatitis patients. Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 20070101
The tert-amino effect in heterocyclic chemistry: synthesis of new fused pyrazolinoquinolizine and 1,4-oxazinopyrazoline derivatives. Beilstein journal of organic chemistry 20070101
Investigation of the excited state structure of DCM via ultrafast electronic pump/vibrational probe. The journal of physical chemistry. B 20060928
Thiourea-catalyzed asymmetric michael addition of activated methylene compounds to alpha,beta-unsaturated imides: dual activation of imide by intra- and intermolecular hydrogen bonding. Journal of the American Chemical Society 20060726
Synthesis of water-soluble, ring-substituted squaraine dyes and their evaluation as fluorescent probes and labels. Analytica chimica acta 20060616
Cloning, overexpression, and characterization of a thermoactive nitrilase from the hyperthermophilic archaeon Pyrococcus abyssi. Protein expression and purification 20060601
Synthesis and molluscicidal activity of some 1,3,4-triaryl-5-chloropyrazole, pyrano[2,3-c]pyrazole, pyrazolylphthalazine and pyrano[2,3-d]thiazole derivatives. Archiv der Pharmazie 20060601
One-step, three-component synthesis of pyridines and 1,4-dihydropyridines with manifold medicinal utility. Organic letters 20060302
[Reaction of pyridinium and quinolinium salts having the leaving group at the 2- or 4-position with active methylene compounds]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20060201
[Reaction of pyridinium salts with active methylene compounds]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20060201
Novel milrinone analogs of pyridine-3-carbonitrile derivatives as promising cardiotonic agents. European journal of medicinal chemistry 20051201
Physical properties and intermolecular dynamics of an ionic liquid compared with its isoelectronic neutral binary solution. The journal of physical chemistry. A 20051027
Elastic, quasielastic, and inelastic neutron-scattering studies on the charge-transfer hexamethylbenzene-tetracyanoquinodimethane complex. The Journal of chemical physics 20050922
Prevention of CS 'tear gas' eye and skin effects and active decontamination with Diphoterine: preliminary studies in 5 French Gendarmes. The Journal of emergency medicine 20050701
A novel synthesis and molluscicidal activity of some functionally substituted pyridine, pyrido[3,2-c]pyridazine, and pyrido[3,2-c]pyridazino[2',3'-a]quinazoline derivatives. Archiv der Pharmazie 20050701
Extensive quinoidal oligothiophenes with dicyanomethylene groups at terminal positions as highly amphoteric redox molecules. Journal of the American Chemical Society 20050629
Solvent-free mechanochemical and one-pot reductive benzylizations of malononitrile and 4-methylaniline using Hantzsch 1,4-dihydropyridine as the reductant. Organic & biomolecular chemistry 20050507
Individual and combined toxicity of nitriles and aldehydes to Raphidocelis subcapitata. Environmental toxicology and chemistry 20050501
Parallel synthesis of strongly fluorescent polysubstituted 2,6-dicyanoanilines via microwave-promoted multicomponent reaction. The Journal of organic chemistry 20050401
Synthesis of new iso-C-nucleoside analogues from 2-(methyl 2-O-benzyl-4,6-O-benzylidene-3-deoxy-alpha-D-altropyranosid-3-yl)ethanal. Carbohydrate research 20050321
Influence of hydroxypropylcyclodextrins on the toxicity of mixtures. Chemosphere 20050301
Post-Hartree-Fock studies on the structure of bis(ortho-substituted phenyl)methylenes. The journal of physical chemistry. A 20050210
Tyrphostins reduce chemotherapy-induced intestinal injury in mice: assessment by a biochemical assay. British journal of cancer 20050131
Spectroscopic studies of the interaction between crown ethers and organic nitriles. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20050114
Preparation, properties, and reduction of heteroaromatic quinoids with 1,4-diazacyclopentadien-2-ylidene terminals. Organic letters 20050106
Functionalization of pyrimidine and purine nucleosides at C4 and C6: C-nucleophilic substitution of their C4- and C6-(1,2,4-triazol-1-yl) derivatives. Nucleosides, nucleotides & nucleic acids 20050101
Knoevenagel reaction in water catalyzed by amine supported on silica gel. Molecular diversity 20050101
Condensation reactions of monomeric hydroxo palladium complexes with active methyl and methylene compounds. Dalton transactions (Cambridge, England : 2003) 20041107
Highly efficient and mild copper-catalyzed N- and C-arylations with aryl bromides and iodides. Chemistry (Weinheim an der Bergstrasse, Germany) 20041105
Palladium-catalyzed addition of mono- and dicarbonyl compounds to conjugated dienes. The Journal of organic chemistry 20041029
Synthesis of novel 6-enaminopurines. Organic & biomolecular chemistry 20040821
Facile synthesis of 1-substituted 2-amino-3-cyanopyrroles: new synthetic precursors for 5,6-unsubstituted pyrrolo[2,3-d]pyrimidines. Organic letters 20040819
Synthesis of some new annulated pyrazolo-pyrido (or pyrano) pyrimidine, pyrazolopyridine and pyranopyrazole derivatives. Acta pharmaceutica (Zagreb, Croatia) 20040601
An application of plastic microchannel-microheater chips to a thermal synthetic reaction. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20040501
Synthesis, antimicrobial activity and conformational analysis of novel substituted pyridines: BF(3)-promoted reaction of hydrazine with 2-alkoxy pyridines. Bioorganic & medicinal chemistry 20040415
Synthesis and some reactions of 3-chloro-2-(cyanomethylene)-1,2-dihydroquinoxalines. Molecules (Basel, Switzerland) 20040331
Synthesis and antimicrobial evaluation of some novel cholestane heterocyclic derivatives. Archiv der Pharmazie 20040301
Synthesis and biological testing of novel analogues of sydnone as potential antibacterial agents. Archiv der Pharmazie 20040301
Synthesis of novel dihydropyridine, dihydropyrimidine, dithioacetal and chalcone derivatives from formylchromones. Bollettino chimico farmaceutico 20040301
Reaction of [60]fullerene with free radicals generated from active methylene compounds by manganese(III) acetate dihydrate. Organic & biomolecular chemistry 20031221
Experimental and computational studies of the structure and vibrational spectra of 2-[5,5-dimethyl-3-(2-phenyl-vinil)-cyclohex-2-enylidene]-malononitrile. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20031201
The conversion of phenylpropanedinitrile (phenylmalononitrile) into the carbanion, followed by IR spectra, ab initio and DFT force field calculations. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20031101
Synthesis of some new thiazole derivatives of pharmaceutical interest. Bollettino chimico farmaceutico 20031101
Synthesis of stable seleno[3,4-b]quinoxaline derivatives. Organic letters 20031030
Receptor-guided alignment-based comparative 3D-QSAR studies of benzylidene malonitrile tyrphostins as EGFR and HER-2 kinase inhibitors. Journal of medicinal chemistry 20031023
Potassium 3-cyano-4-(dicyanomethylene)-5-oxo-4,5-dihydro-1H-pyrrol-2-olate. Acta crystallographica. Section C, Crystal structure communications 20031001
Development of QSARs for predicting the joint effects between cyanogenic toxicants and aldehydes. Chemical research in toxicology 20031001
Studies on thiazolopyridines--a novel synthesis of bis-thiazolopyridines as promising antimicrobial agents. Acta pharmaceutica (Zagreb, Croatia) 20030901
Crystal structure of a methine dye, C.I. Disperse Blue 354. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20030801
A highly efficient catalytic system for cross-coupling of aryl chlorides and bromides with malononitrile anion by palladium carbene complexes. Chemical communications (Cambridge, England) 20030621
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Efficient synthesis of 3H-imidazo[4,5-b]pyridines from malononitrile and 5-amino-4-(cyanoformimidoyl)imidazoles. The Journal of organic chemistry 20030124
Non-classical antifolates, 5-(N-phenylpyrrolidin-3-yl)-2,4,6-triaminopyrimidines and 2,4-Diamino-6(5H)-oxopyrimidines, synthesis and antitumor studies. Bioorganic & medicinal chemistry 20030102
Solid-phase synthesis of 2-substituted 4-amino-7-oxo-5,6,7,8-tetrahydropyrido[2,3-d]pyrimidines: an example of cyclization-assisted cleavage. Molecular diversity 20030101
Solid-phase synthesis of 2-substituted 4-amino-7-oxo-5,6,7,8-tetrahydropyrido[2,3-d]pyrimidines. Molecular diversity 20030101
A one-pot microwave-assisted synthesis of pyrido[2,3-d]pyrimidines. Molecular diversity 20030101
Tetrazole synthesis via the palladium-catalyzed three component coupling reaction. Molecular diversity 20030101
Mechanism of the Synergistic Toxicity of Malononitrile and p -Nitrobenzaldehyde with Photobacterium phosphoreum. Toxicology mechanisms and methods 20030101
Engineering a remarkably low HOMO-LUMO gap by covalent linkage of a strong pi-donor and a pi-acceptor--tetrathiafulvalene-sigma-polynitrofluorene diads: their amphoteric redox behavior, electron transfer and spectroscopic properties. Chemistry (Weinheim an der Bergstrasse, Germany) 20021018
Quinonoid oligothiophenes as electron-donor and electron-acceptor materials. A spectroelectrochemical and theoretical study. Journal of the American Chemical Society 20021016
Influence of filled d pi-manifold and L/L' ligands on the structure, basicity, and bond rotations of the octahedral and d(6) amido complexes TpRu(L)(L')(NHPh) (Tp = hydridotris(pyrazolyl)borate; L = L' = PMe(3) or P(OMe)(3), or L = CO and L' = PPh(3)): solid-state structures of [TpRu(PMe(3))(2)(NH(2)Ph)][OTf], [TpRu[P(OMe)(3)](2)(NH(2)Ph)][OTf], and TpRu[P(OMe)(3)](2)(NHPh). Inorganic chemistry 20020603
Synthesis of new 2-thiouracil-5-sulfonamide derivatives with biological activity. Archives of pharmacal research 20020601
Pyrido[2, 3-d]pyrimidines and pyrimido[5',4':5, 6]pyrido[2, 3-d]pyrimidines as new antiviral agents: synthesis and biological activity. Archiv der Pharmazie 20020601
A pi-stacking terthiophene-based quinodimethane is an n-channel conductor in a thin film transistor. Journal of the American Chemical Society 20020424
Novel photo-induced coupling reaction of 9-fluorenylidenemalononitrile with 10-methyl-9,10-dihydroacridine. Chemical communications (Cambridge, England) 20020421
Catalytic radical addition of carbonyl compounds to alkenes by Mn(II)/Co(II)/O(2) system. The Journal of organic chemistry 20020208
One-step synthesis of substituted 6-amino-5-cyanospiro-4-(piperidine-4')- 2H,4H-dihydropyrazolo[3,4-b]pyrans. Organic letters 20020207
New 3-pyridinecarbonitrile derivatives and their antimicrobial properties. Bollettino chimico farmaceutico 20020101
Synthesis of 1-(2-naphthylsulfonyl)pyrazole-C-glycosides. Nucleosides, nucleotides & nucleic acids 20020101
Synthesis of some new azoles and azines and their condensed derivatives. Bollettino chimico farmaceutico 20020101
NMR experimental evidence of the differentiation of enantiotopic directions in C(s) and C(2v) molecules using partially oriented, chiral media. Journal of the American Chemical Society 20011205
Synthesis of derivatives of C-nucleoside analogues using 'push-pull' functionalized monosaccharides. Carbohydrate research 20010712
Piperidine as an efficient organic catalyst of derivatization of oligosaccharides with malononitrile for high-sensitivity electrospray ionization mass analysis. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20010701
Experimental and ab initio MO studies on the IR spectra and structure of pyridinium dicyanomethylide and trimethylammonium dicyanomethylide. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20010101
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