Antinociceptive effect of intrathecal loperamide: role of mu-opioid receptor and calcium channels.

European journal of pharmacology 20121205

P-glycoprotein, multidrug-resistance associated protein 2, Cyp3a, and carboxylesterase affect the oral availability and metabolism of vinorelbine.

Molecular pharmacology 20121001

Characterization of SAGE Mdr1a (P-gp), Bcrp, and Mrp2 knockout rats using loperamide, paclitaxel, sulfasalazine, and carboxydichlorofluorescein pharmacokinetics.

Drug metabolism and disposition: the biological fate of chemicals 20120901

Loperamide effects on anxiety level and feeding behavior in rats. Role of vagal afferentation.

Bulletin of experimental biology and medicine 20120901

Analgesic properties of loperamide differ following systemic and local administration to rats after spinal nerve injury.

European journal of pain (London, England) 20120801

Garcinia buchananii bark extract is an effective anti-diarrheal remedy for lactose-induced diarrhea.

Journal of ethnopharmacology 20120713

The effects of loperamide, or loperamide plus simethicone, on the distribution of gut water as assessed by MRI in a mannitol model of secretory diarrhoea.

Alimentary pharmacology & therapeutics 20120701

Urinary bladder relaxation through activation of opioid μ-receptors induced by loperamide is increased in diabetic rats.

Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20120601

Behavioral effects and central nervous system levels of the broadly available κ-agonist hallucinogen salvinorin A are affected by P-glycoprotein modulation in vivo.

The Journal of pharmacology and experimental therapeutics 20120601

Combining PET biodistribution and equilibrium dialysis assays to assess the free brain concentration and BBB transport of CNS drugs.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20120501

Dissecting the relative contribution of central versus peripheral opioid analgesia: are the analgesic and adverse effects of opioids inseparable?

European journal of pain (London, England) 20120501

Relative contributions of peripheral versus supraspinal or spinal opioid receptors to the antinociception of systemic opioids.

European journal of pain (London, England) 20120501

Assessment of the aversive effects of peripheral mu opioid receptor agonism in Fischer 344 and Lewis rats.

Pharmacology, biochemistry, and behavior 20120401

Discovery of loperamide as an antagonist of angiopoietin1 and angiopoietin2 by virtual screening.

Bioorganic & medicinal chemistry letters 20120401

[Evaluation of P-glycoprotein mediated in vitro loperamide biliary excretion with sandwich-cultured rat hepatocytes model].

Yao xue xue bao = Acta pharmaceutica Sinica 20120401

Opiate-induced constipation related to activation of small intestine opioid μ2-receptors.

World journal of gastroenterology 20120328

P-glycoprotein-based loperamide-cyclosporine drug interaction at the rat blood-brain barrier: prediction from in vitro studies and extrapolation to humans.

Molecular pharmaceutics 20120305

Carboxylesterase expression in human dental pulp cells: role in regulation of BisGMA-induced prostanoid production and cytotoxicity.

Acta biomaterialia 20120301

Loperamide, an antidiarrhea drug, has antitumor activity by inducing cell apoptosis.

Pharmacological research 20120301

Effects of Ficus carica paste on loperamide-induced constipation in rats.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120301

Antidiarrhetic loperamide hydrochloride.

Acta crystallographica. Section C, Crystal structure communications 20120301

The influence of mass of [11C]-laniquidar and [11C]-N-desmethyl-loperamide on P-glycoprotein blockage at the blood-brain barrier.

Nuclear medicine and biology 20120101

Effects of oral loperamide on efficacy of naltrexone, baclofen and AM-251 in blocking ethanol self-administration in rats.

Pharmacology, biochemistry, and behavior 20120101

Irritable bowel syndrome.

BMJ clinical evidence 20120101

Prostatic relaxation induced by loperamide is reduced in spontaneously hypertensive rats.

TheScientificWorldJournal 20120101

Effect of colic vein ligature in rats with loperamide-induced constipation.

Journal of biomedicine & biotechnology 20120101

Quantification of polyphenols and pharmacological analysis of water and ethanol-based extracts of cultivated agarwood leaves.

Journal of nutritional science and vitaminology 20120101

Local loperamide injection reduces mechanosensitivity of rat cutaneous, nociceptive C-fibers.

PloS one 20120101

Effect of acupuncture for gastrointestinal activity differs depending on the pathophysiological condition.

Acupuncture in medicine : journal of the British Medical Acupuncture Society 20111201

Estimation of P-glycoprotein-mediated efflux in the oral absorption of P-gp substrate drugs from simultaneous analysis of drug dissolution and permeation.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20111120

Pediatric lymphocytic colitis presenting with intractable diarrhea.

Journal of pediatric gastroenterology and nutrition 20111101

Sterile hepatic abscess secondary to administration of parenteral fluids via an umbilical venous catheter in a premature baby.

Journal of pediatric gastroenterology and nutrition 20111101

Determination of loperamide in mdr1a/1b knock-out mouse brain tissue using matrix-assisted laser desorption/ionization mass spectrometry and comparison with quantitative electrospray-triple quadrupole mass spectrometry analysis.

Archives of pharmacal research 20111101

Loperamide.

Journal of pain and symptom management 20110801

Can loperamide cause acute pancreatitis?

Pancreas 20110701

Antidiarrheal effect of fractions from stem bark of Thespesia populnea in rodents: Possible antimotility and antisecretory mechanisms.

Asian Pacific journal of tropical medicine 20110601

Toxicological evaluation of aqueous extract of Aloe ferox Mill. in loperamide-induced constipated rats.

Human & experimental toxicology 20110501

Antimicrobial and antimotility agent use in persons with shiga toxin-producing Escherichia coli O157 infection in FoodNet Sites.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20110501

Investigation on mechanisms of glycopeptide nanoparticles for drug delivery across the blood-brain barrier.

Nanomedicine (London, England) 20110401

Relapse of intestinal and hepatic amebiasis after treatment.

Digestive diseases and sciences 20110301

Antiepileptic drugs modulate P-glycoproteins in the brain: a mice study with (11)C-desmethylloperamide.

Epilepsy research 20110301

Loperamide-induced rat prostate relaxation through activation of peripheral µ-opioid receptors.

Neurourology and urodynamics 20110301

Targeting the insulin receptor: nanoparticles for drug delivery across the blood-brain barrier (BBB).

Journal of drug targeting 20110201

Loperamide, an FDA-approved antidiarrhea drug, effectively reverses the resistance of multidrug resistant MCF-7/MDR1 human breast cancer cells to doxorubicin-induced cytotoxicity.

Cancer investigation 20110201

Changes in feeding behavior after peripheral loperamide administration in rats.

Bulletin of experimental biology and medicine 20110201

An unusual treatment for protein losing enteropathy.

Congenital heart disease 20110101

Activation of peripheral opioid µ-receptors in blood vessel may lower blood pressure in spontaneously hypertensive rats.

Pharmacology 20110101

[Central and peripheral mu-opioid systems in the mechanisms of emotional stress].

Vestnik Rossiiskoi akademii meditsinskikh nauk 20110101

Gastroenteritis in children.

BMJ clinical evidence 20110101

Fitting the elementary rate constants of the P-gp transporter network in the hMDR1-MDCK confluent cell monolayer using a particle swarm algorithm.

PloS one 20110101

Involvement of peripheral mu opioid receptors in scratching behavior in mice.

European journal of pharmacology 20101215

Hyperpolarization-activated cyclic nucleotide-gated channels in olfactory sensory neurons regulate axon extension and glomerular formation.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20101208

A predictive ligand-based Bayesian model for human drug-induced liver injury.

Drug metabolism and disposition: the biological fate of chemicals 20101201

Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Bioorganic & medicinal chemistry letters 20101101

Oral bioavailability of P-glycoprotein substrate drugs do not differ between ABCB1-1Δ and ABCB1 wild type dogs.

Journal of veterinary pharmacology and therapeutics 20101001

Interference with P-glycoprotein improves ivermectin activity against adult resistant nematodes in sheep.

Veterinary parasitology 20100920

Calcium channel blocking activity of Mentha longifolia L. explains its medicinal use in diarrhoea and gut spasm.

Phytotherapy research : PTR 20100901

Peripheral administration of loperamide and methylnaloxone decreases the degree of anxiety in rats.

Bulletin of experimental biology and medicine 20100901

Remarks and questions on the article 'Prospective randomized double-blind trial of racecadotril compared with loperamide in elderly people with gastroenteritis living in nursing homes'.

European journal of clinical pharmacology 20100801

Lactic acid fermentation of germinated barley fiber and proliferative function of colonic epithelial cells in loperamide-induced rats.

Journal of medicinal food 20100801

Changes in β-endorphin level in the cingulate cortex in rats after peripheral loperamide and methylnaloxone administration at rest and during emotional stress.

Bulletin of experimental biology and medicine 20100801

Traditional Chinese formula, lubricating gut pill, improves loperamide-induced rat constipation involved in enhance of Cl- secretion across distal colonic epithelium.

Journal of ethnopharmacology 20100720

Sialic acid and glycopeptides conjugated PLGA nanoparticles for central nervous system targeting: In vivo pharmacological evidence and biodistribution.

Journal of controlled release : official journal of the Controlled Release Society 20100701

Cattle nematodes resistant to macrocyclic lactones: comparative effects of P-glycoprotein modulation on the efficacy and disposition kinetics of ivermectin and moxidectin.

Experimental parasitology 20100601

N-desmethyl-loperamide is selective for P-glycoprotein among three ATP-binding cassette transporters at the blood-brain barrier.

Drug metabolism and disposition: the biological fate of chemicals 20100601

Review article: rifaximin, a minimally absorbed oral antibacterial, for the treatment of travellers' diarrhoea.

Alimentary pharmacology & therapeutics 20100601

NPY Y2 receptor agonist PYY(3-36) inhibits diarrhea by reducing intestinal fluid secretion and slowing colonic transit in mice.

Peptides 20100401

P-glycoprotein function at the blood-brain barrier in humans can be quantified with the substrate radiotracer 11C-N-desmethyl-loperamide.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20100401

Effects of ketoconazole on the biodistribution and metabolism of [11C]loperamide and [11C]N-desmethyl-loperamide in wild-type and P-gp knockout mice.

Nuclear medicine and biology 20100401

Loperamide and P-glycoprotein inhibition: assessment of the clinical relevance.

The Journal of pharmacy and pharmacology 20100401

Administration of loperamide and addition of wheat bran to the diets of weaner pigs decrease the incidence of diarrhoea and enhance their gut maturation.

The British journal of nutrition 20100301

Acceleration of the gastrointestinal transit by polyethylene glycol effectively treats unconjugated hyperbilirubinaemia in Gunn rats.

Gut 20100301

D-lactic acidosis and ataxia in a man with Crohn disease.

CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20100223

Drug delivery to the brain using surfactant-coated poly(lactide-co-glycolide) nanoparticles: influence of the formulation parameters.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20100201

Prospective randomized double-blind trial of racecadotril compared with loperamide in elderly people with gastroenteritis living in nursing homes.

European journal of clinical pharmacology 20100201

Implementation of droplet-membrane-droplet liquid-phase microextraction under stagnant conditions for lab-on-a-chip applications.

Analytica chimica acta 20100125

Antidiarrhoeal and spasmolytic activities of the methanolic crude extract of Alstonia scholaris L. are mediated through calcium channel blockade.

Phytotherapy research : PTR 20100101

Improved measurement of drug exposure in the brain using drug-specific correction for residual blood.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20100101

Crohn's colitis with perianal disease complicated by collagenous colitis: discourse on management options.

Digestion 20100101

Laxative activities of Mareya micrantha (Benth.) Müll. Arg. (Euphorbiaceae) leaf aqueous extract in rats.

BMC complementary and alternative medicine 20100101

Antidiarrheal activity of aqueous extract of Hermannia incana Cav. leaves in Wistar rats.

Methods and findings in experimental and clinical pharmacology 20100101

Anti-diarrhoeal activity of crude aqueous extract of Rubia tinctorum L. roots in rodents.

Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi 20100101

Using PET studies of P-gp function to elucidate mechanisms underlying the disposition of drugs.

Current topics in medicinal chemistry 20100101

Diarrhoea in a large prospective cohort of European travellers to resource-limited destinations.

BMC infectious diseases 20100101

Agarwood induced laxative effects via acetylcholine receptors on loperamide-induced constipation in mice.

Bioscience, biotechnology, and biochemistry 20100101

The effect of Aloe ferox Mill. in the treatment of loperamide-induced constipation in Wistar rats.

BMC gastroenterology 20100101

Irritable bowel syndrome.

BMJ clinical evidence 20100101

Nanoparticles as drug delivery agents specific for CNS: in vivo biodistribution.

Nanomedicine : nanotechnology, biology, and medicine 20091201

Mediation of protein kinase C zeta in mu-opioid receptor activation for increase of glucose uptake into cultured myoblast C2C12 cells.

Neuroscience letters 20091113

The delayed phase of cisplatin-induced emesis is mediated by the area postrema and not the abdominal visceral innervation in the ferret.

Neuroscience letters 20091106

Regional differences in capillary density, perfusion rate, and P-glycoprotein activity: a quantitative analysis of regional drug exposure in the brain.

Biochemical pharmacology 20091015

Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

Nature chemical biology 20091001

Diabetic diarrhea.

Current gastroenterology reports 20091001

Modulation of peripheral opioid receptors affects the concentration of mu-opioid receptors in rat brain.

Bulletin of experimental biology and medicine 20090901

Human brain imaging and radiation dosimetry of 11C-N-desmethyl-loperamide, a PET radiotracer to measure the function of P-glycoprotein.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20090501

Treatment approaches to irritable bowel syndrome.

Pediatric annals 20090501

Irritable bowel syndrome: a mild disorder; purely symptomatic treatment.

Prescrire international 20090401

An ion pairing approach to increase the loading of hydrophilic and lipophilic drugs into PEGylated PLGA nanoparticles.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20090201

Transferrin- and transferrin-receptor-antibody-modified nanoparticles enable drug delivery across the blood-brain barrier (BBB).

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20090201

P-glycoprotein function at the blood-brain barrier imaged using 11C-N-desmethyl-loperamide in monkeys.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20090101

Competitive substrates for P-glycoprotein and organic anion protein transporters differentially reduce blood organ transport of fentanyl and loperamide: pharmacokinetics and pharmacodynamics in Sprague-Dawley rats.

Anesthesia and analgesia 20090101

Efficacy of methylcellulose and loperamide in managing fecal incontinence.

Acta obstetricia et gynecologica Scandinavica 20090101

Expert review of the evidence base for self-therapy of travelers' diarrhea.

Journal of travel medicine 20090101

Pathogenesis and management of irritable bowel syndrome.

Tropical gastroenterology : official journal of the Digestive Diseases Foundation 20090101

Characterization of two models of drug-induced constipation in mice and evaluation of mustard oil in these models.

Pharmacology 20090101

Spinal antinociceptive action of loperamide is mediated by opioid receptors in the formalin test in rats.

Neuroscience letters 20081231

[Hazardous to give loperamide (Immodium etc) to children under three years of age].

Lakartidningen 20081217

Comparison and validation of drug loading parameters of PEGylated nanoparticles purified by a diafiltration centrifugal device and tangential flow filtration.

Drug development and industrial pharmacy 20081201

Potential utility of peripherally applied loperamide in oral chronic graft-versus-host disease related pain.

Japanese journal of clinical oncology 20081201

Tariquidar, a selective P-glycoprotein inhibitor, does not potentiate loperamide's opioid brain effects in humans despite full inhibition of lymphocyte P-glycoprotein.

Anesthesiology 20081201

Outcomes of combination treatment of fecal incontinence in women.

American journal of obstetrics and gynecology 20081201

[A case of giant cell microscopic colitis?].

Annales de pathologie 20081201

Antidiarrhoeal activity of Psidium guajava Linn. (Myrtaceae) leaf aqueous extract in rodents.

Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi 20081201

Hypothesis on reciprocal interactions between the central and peripheral components of the endogenous opioid system.

Bulletin of experimental biology and medicine 20081201

Local loperamide inhibits thermal hyperalgesia but not mechanical allodynia induced by intratibial inoculation of melanoma cells in mice.

Cellular and molecular neurobiology 20081101

Loperamide for the treatment of traveler's diarrhea: broad or narrow usefulness?

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20081015

Effect of adjunctive loperamide in combination with antibiotics on treatment outcomes in traveler's diarrhea: a systematic review and meta-analysis.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20081015

Synthesis and evaluation of [N-methyl-11C]N-desmethyl-loperamide as a new and improved PET radiotracer for imaging P-gp function.

Journal of medicinal chemistry 20081009

The effects of herkinorin, the first mu-selective ligand from a salvinorin A-derived scaffold, in a neuroendocrine biomarker assay in nonhuman primates.

The Journal of pharmacology and experimental therapeutics 20081001

Inappropriate use of loperamide worsens Clostridium difficile-associated diarrhoea.

The Journal of hospital infection 20081001

Validation of 13C-acetic acid breath test by measuring effects of loperamide, morphine, mosapride, and itopride on gastric emptying in mice.

Biological & pharmaceutical bulletin 20081001

Changes of intestinal mucosal and plasma PYY in a diarrhea model rat and influence of loperamide as the treatment agent for diarrhea.

Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20080901

Peripherally acting mu-opioid receptor agonist attenuates neuropathic pain in rats after L5 spinal nerve injury.

Pain 20080831

Diarrhea in adults (acute).

American family physician 20080815

In situ dissolution testing using potentiometric sensors.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20080807

[Clinical efficacy of buzhong yiqi pill combined with imodium in treating post-operational diarrhea in patients of colonic cancer].

Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20080801

Drugs for traveler's diarrhea.

The Medical letter on drugs and therapeutics 20080728

Fibre supplementation in addition to loperamide for faecal incontinence in adults: a randomized trial.

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland 20080701

Cannabidiol, extracted from Cannabis sativa, selectively inhibits inflammatory hypermotility in mice.

British journal of pharmacology 20080701

Effects of serotonin 5-HT(3) receptor antagonists on CRF-induced abnormal colonic water transport and defecation in rats.

European journal of pharmacology 20080610

P-glycoprotein contributes to the blood-brain, but not blood-cerebrospinal fluid, barrier in a spontaneous canine p-glycoprotein knockout model.

Drug metabolism and disposition: the biological fate of chemicals 20080601

[Topic: Treating travelers' diarrhea. When should medication be given?].

Der Urologe. Ausg. A 20080601

Modest effect of impaired P-glycoprotein on the plasma concentrations of fexofenadine, quinidine, and loperamide following oral administration in collies.

Drug metabolism and disposition: the biological fate of chemicals 20080501

Maternal use of loperamide in early pregnancy and delivery outcome.

Acta paediatrica (Oslo, Norway : 1992) 20080501

Medical prevention and treatment of acute and chronic radiation induced enteritis--is there any proven therapy? a short review.

Zeitschrift fur Gastroenterologie 20080501

Limited effects of beta-endorphin compared to loperamide or fentanyl in a neuroendocrine biomarker assay in non-human primates.

Psychoneuroendocrinology 20080401

Binding site of loperamide: automated docking of loperamide in human mu- and delta-opioid receptors.

Chemical biology & drug design 20080401

11C-loperamide and its N-desmethyl radiometabolite are avid substrates for brain permeability-glycoprotein efflux.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20080401

Novel trans-3,4-dimethyl-4-(3-hydroxyphenyl)piperidines as mu opioid receptor antagonists with improved opioid receptor selectivity profiles.

Bioorganic & medicinal chemistry letters 20080315

Novel pharmacological activity of loperamide and CP-339,818 on human HCN channels characterized with an automated electrophysiology assay.

European journal of pharmacology 20080226

Kinetic identification of membrane transporters that assist P-glycoprotein-mediated transport of digoxin and loperamide through a confluent monolayer of MDCKII-hMDR1 cells.

Drug metabolism and disposition: the biological fate of chemicals 20080201

Enhanced peripheral analgesia using virally mediated gene transfer of the mu-opioid receptor in mice.

Anesthesiology 20080201

Inhibitory effects of ramosetron, a potent and selective 5-HT3-receptor antagonist, on conditioned fear stress-induced abnormal defecation and normal defecation in rats: comparative studies with antidiarrheal and spasmolytic agents.

Journal of pharmacological sciences 20080201

Inhibition of phosphodiesterase type 4 decreases stress-induced defecation in rats and mice.

Pharmacology 20080101

The role of loperamide in gastrointestinal disorders.

Reviews in gastroenterological disorders 20080101

[Antibiotic-associated diarrheas in phthisiatric care: standardization of their diagnosis, treatment, prevention, examination of health care quality].

Problemy tuberkuleza i boleznei legkikh 20080101

[Treating travelers' diarrhea. When should medication be given?].

Der Internist 20071201

Effect of ramosetron on conditioned emotional stress-induced colonic dysfunction as a model of irritable bowel syndrome in rats.

European journal of pharmacology 20071114

Specificity of procaine and ester hydrolysis by human, minipig, and rat skin and liver.

Drug metabolism and disposition: the biological fate of chemicals 20071101

Targeting the central nervous system: in vivo experiments with peptide-derivatized nanoparticles loaded with Loperamide and Rhodamine-123.

Journal of controlled release : official journal of the Controlled Release Society 20070911

Purification of PEGylated nanoparticles using tangential flow filtration (TFF).

Drug development and industrial pharmacy 20070901

Death due to anaphylactic shock after ingestion of Imodium instants (Loperamide).

Allergy 20070801

[Diagnostic and therapeutic guidelines for entero-cutaneous fistulas. Personal experience and literature review].

Minerva chirurgica 20070801

Azithromycin and loperamide are comparable to levofloxacin and loperamide for the treatment of traveler's diarrhea in United States military personnel in Turkey.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20070801

Relative contribution of peripheral versus central opioid receptors to antinociception.

Brain research 20070730

Involvement of nitric oxide in the inhibition of bone cancer-induced hyperalgesia through the activation of peripheral opioid receptors in mice.

Neuropharmacology 20070701

Effects of loperamide on mechanical allodynia induced by herpes simplex virus type-1 in mice.

Journal of pharmacological sciences 20070701

Evaluation of the pharmacological profile of ramosetron, a novel therapeutic agent for irritable bowel syndrome.

Journal of pharmacological sciences 20070701

Collagenous colitis in a patient with systemic sclerosis: a rare entity.

Journal of the National Medical Association 20070601

Chemotherapy-induced mucositis: focusing on diarrhea.

The journal of supportive oncology 20070601

A case of toxic megacolon secondary to Clostridium difficile-associated diarrhea worsened after administration of an antimotility agent and molecular analysis of recovered isolates.

Journal of gastroenterology 20070601

Direct inhibition of Ih by analgesic loperamide in rat DRG neurons.

Journal of neurophysiology 20070501

Randomized, double-blind, placebo-controlled clinical trial of loperamide plus simethicone versus loperamide alone and simethicone alone in the treatment of acute diarrhea with gas-related abdominal discomfort.

Current medical research and opinion 20070501

Treatment of travelers' diarrhea: randomized trial comparing rifaximin, rifaximin plus loperamide, and loperamide alone.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20070401

86-year-old woman with abdominal pain and diarrhea.

Mayo Clinic proceedings 20070401

Activation of mu-opioid receptors improves insulin sensitivity in obese Zucker rats.

Life sciences 20070327

Pharmacological modulation of gut mucosal and large vessel blood flow.

Alimentary pharmacology & therapeutics 20070315

Covalent attachment of apolipoprotein A-I and apolipoprotein B-100 to albumin nanoparticles enables drug transport into the brain.

Journal of controlled release : official journal of the Controlled Release Society 20070312

Pharmacotherapy for microscopic colitis.

Pharmacotherapy 20070301

[Drug treatment of irritable bowel syndrome: an unmet need].

Gastroenterologia y hepatologia 20070301

Loperamide therapy for acute diarrhea in children: systematic review and meta-analysis.

PLoS medicine 20070301

Use of probiotics for prevention of radiation-induced diarrhea.

World journal of gastroenterology 20070214

Antihyperalgesic effects of loperamide in a model of rat neuropathic pain are mediated by peripheral delta-opioid receptors.

Neuroscience letters 20070110

Fulminant amoebic colitis following loperamide use.

Journal of travel medicine 20070101

Loperamide cause of prolonged urinary retention after acute gastroenteritis.

European review for medical and pharmacological sciences 20070101

Loperamide plus azithromycin more effectively treats travelers' diarrhea in Mexico than azithromycin alone.

Journal of travel medicine 20070101

The benefits of loperamide in the treatment of patients with IBS or IBD. Introduction.

Reviews in gastroenterological disorders 20070101

Loperamide: a pharmacological review.

Reviews in gastroenterological disorders 20070101

Treatment of diarrhea in patients with inflammatory bowel disease: concepts and cautions.

Reviews in gastroenterological disorders 20070101

P-Glycoprotein (P-gp) expressed in a confluent monolayer of hMDR1-MDCKII cells has more than one efflux pathway with cooperative binding sites.

Biochemistry 20061226

Investigation on the relationship between cannabinoid CB1 and opioid receptors in gastrointestinal motility in mice.

British journal of pharmacology 20060801

Intrasperm Ca2+ modulation and human ejaculated sperm viability: influence of miconazole, clotrimazole and loperamide.

The Journal of pharmacy and pharmacology 20060801

Differential in vivo sensitivity to inhibition of P-glycoprotein located in lymphocytes, testes, and the blood-brain barrier.

The Journal of pharmacology and experimental therapeutics 20060601

Covalent linkage of apolipoprotein e to albumin nanoparticles strongly enhances drug transport into the brain.

The Journal of pharmacology and experimental therapeutics 20060601

Itraconazole, gemfibrozil and their combination markedly raise the plasma concentrations of loperamide.

European journal of clinical pharmacology 20060601

Synthesis and pharmacological activity of 2-(substituted)-3-{2-[(4-phenyl-4-cyano)piperidino]ethyl}-1,3-thiazolidin-4-ones.

Chemical biology & drug design 20060601

Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Effect of opioid mu-receptors activation on insulin signals damaged by tumor necrosis factor alpha in myoblast C2C12 cells.

Neuroscience letters 20060424

In silico and in vitro screening for inhibition of cytochrome P450 CYP3A4 by comedications commonly used by patients with cancer.

Drug metabolism and disposition: the biological fate of chemicals 20060401

mu-Opiate receptor agonists -- a new pharmacological approach to prevent motion sickness?

British journal of clinical pharmacology 20060101

Synthesis and smooth muscle-selective relaxant activity of a piperidine analogue: 1-(4'-fluorophenacyl)-4-hydroxy-4-phenyl-piperidinium chloride.

Archives of pharmacal research 20060101

Loperamide: a potential topical analgesic for the treatment of burn pain.

Journal of burn care & research : official publication of the American Burn Association 20060101

Octreotide long-acting formulation (LAR) in chronic loperamide-refractory diarrhea not related to cancer treatment.

Anticancer research 20060101

Drug interactions and pharmacogenetic reactions are the basis for chloroquine and mefloquine-induced psychosis.

Medical hypotheses 20060101

Desorption electrospray ionisation mass spectrometry and tandem mass spectrometry of low molecular weight synthetic polymers.

Rapid communications in mass spectrometry : RCM 20060101

Octreotide in the management of chemoradiotherapy-induced diarrhea refractory to loperamide in patients with rectal carcinoma.

Oncology 20060101

Treatment of irritable bowel syndrome.

American family physician 20051215

[New views on antidiarrheal effect of wood creosote: is wood creosote really a gastrointestinal antiseptic?].

Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20051201

Analgesic effects of morphine and loperamide in the rat formalin test: interactions with NMDA receptor antagonists.

European journal of pharmacology 20051121

Saccharomyces boulardii inhibits water and electrolytes changes induced by castor oil in the rat colon.

Digestive diseases and sciences 20051101

[Traveller's diarrhea].

Ugeskrift for laeger 20051024

Block of delayed-rectifier potassium channels by reduced haloperidol and related compounds in mouse cortical neurons.

The Journal of pharmacology and experimental therapeutics 20051001

The steady-state Michaelis-Menten analysis of P-glycoprotein mediated transport through a confluent cell monolayer cannot predict the correct Michaelis constant Km.

Pharmaceutical research 20051001

mu-Opiate receptor agonist loperamide blocks bethanechol-induced gallbladder contraction, despite higher cholecystokinin plasma levels in man.

Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20051001

Tissue distribution of loperamide and N-desmethylloperamide following a fatal overdose.

Journal of analytical toxicology 20051001

The effects of loperamide on continence problems and anorectal function in obese subjects taking orlistat.

Digestive diseases and sciences 20050901

Activation of opioid mu-receptors by loperamide to improve interleukin-6-induced inhibition of insulin signals in myoblast C2C12 cells.

Diabetologia 20050701

Hydrolysis of capecitabine to 5'-deoxy-5-fluorocytidine by human carboxylesterases and inhibition by loperamide.

The Journal of pharmacology and experimental therapeutics 20050601

Acute colitis induction by oil of mustard results in later development of an IBS-like accelerated upper GI transit in mice.

American journal of physiology. Gastrointestinal and liver physiology 20050601

Physical stability of the amorphous state of loperamide and two fragment molecules in solid dispersions with the polymers PVP-K30 and PVP-VA64.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20050601

Loperamide inhibits tachykinin NK3-receptor-triggered serotonin release without affecting NK2-receptor-triggered serotonin release from guinea pig colonic mucosa.

Journal of pharmacological sciences 20050601

Gastroenteritis in children.

Clinical evidence 20050601

Comparison between prospective and retrospective evaluation of Crohn's disease activity index.

The American journal of gastroenterology 20050501

Analgesic effects of loperamide in bone cancer pain in mice.

Pharmacology, biochemistry, and behavior 20050501

Acute analgesic effect of loperamide as compared to morphine after intrathecal administration in rat.

Indian journal of experimental biology 20050501

Nociceptive sensitivity and opioid antinociception and antihyperalgesia in Freund's adjuvant-induced arthritic male and female rats.

The Journal of pharmacology and experimental therapeutics 20050401

Loperamide.

Nursing times 20050401

A blind, randomized comparison of racecadotril and loperamide for stopping acute diarrhea in adults.

World journal of gastroenterology 20050314

Relationship between loperamide-induced sedative effect and digoxin pharmacokinetics in healthy Japanese subjects.

Pharmaceutical research 20050301

[Time and again digestion problems. What really helps in irritable bowel syndrome?].

MMW Fortschritte der Medizin 20050224

[Fixed drug eruption associated to loperamide].

Medicina clinica 20050212

Validation of a liquid chromatographic-tandem mass spectrometric method for the determination of loperamide in human plasma.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050125

The elementary mass action rate constants of P-gp transport for a confluent monolayer of MDCKII-hMDR1 cells.

Biophysical journal 20050101

Study of the physicochemical properties and stability of solid dispersions of loperamide and PEG6000 prepared by spray drying.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20050101

Loperamide inhibits the biliary excretion of irinotecan (CPT-11) in the rat isolated perfused liver.

The Journal of pharmacy and pharmacology 20050101

Salt formation in solid dispersions consisting of polyacrylic acid as a carrier and three basic model compounds resulting in very high glass transition temperatures and constant dissolution properties upon storage.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20050101

Effects of fasting on evaluation of gastrointestinal transit with charcoal meal.

Journal of pharmacological and toxicological methods 20050101

Effectiveness of step-wise intervention plan for managing nelfinavir-associated diarrhea: a pilot study.

HIV clinical trials 20050101

Gastroenteritis in children.

Clinical evidence 20041201

A phase I trial of perifosine (NSC 639966) on a loading dose/maintenance dose schedule in patients with advanced cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research 20041115

Liquid chromatography-tandem mass spectrometry determination of loperamide and its main metabolite desmethylloperamide in biological specimens and application to forensic cases.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20041105

LC-MS determination and bioavailability study of loperamide hydrochloride after oral administration of loperamide capsule in human volunteers.

Journal of pharmaceutical and biomedical analysis 20041029

Antiallodynic effects of loperamide and fentanyl against topical capsaicin-induced allodynia in unanesthetized primates.

The Journal of pharmacology and experimental therapeutics 20041001

New approaches to prevent intestinal toxicity of irinotecan-based regimens.

Cancer treatment reviews 20041001

Identification of cytochrome P450 isoforms involved in the metabolism of loperamide in human liver microsomes.

European journal of clinical pharmacology 20041001

Use of loperamide as a phenotypic probe of mdr1a status in CF-1 mice.

Pharmaceutical research 20041001

Multicenter, double-blind, randomized comparison of wood creosote, the principal active ingredient of Seirogan, an herbal antidiarrheal medication, and loperamide in adults with acute nonspecific diarrhea.

Clinical therapeutics 20041001

Identification of an N-methyl-4-phenylpyridinium-like metabolite of the antidiarrheal agent loperamide in human liver microsomes: underlying reason(s) for the lack of neurotoxicity despite the bioactivation event.

Drug metabolism and disposition: the biological fate of chemicals 20040901

[Severe adverse effects of certain veterinary drugs in collies and collie-like dogs].

Tijdschrift voor diergeneeskunde 20040901

Phase behaviour analysis of solid dispersions of loperamide and two structurally related compounds with the polymers PVP-K30 and PVP-VA64.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20040801

Neomycin as secondary prophylaxis for irinotecan-induced diarrhea.

Annals of oncology : official journal of the European Society for Medical Oncology 20040801

[Loss of consciousness in a child due to loperamide].

Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 20040701

[Management of chemotherapy induced diarrhea].

Zeitschrift fur Gastroenterologie 20040601

pH dependent uptake of loperamide across the gastrointestinal tract: an in vitro study.

Drug development and industrial pharmacy 20040501

Effect of finite doses of propylene glycol on enhancement of in vitro percutaneous permeation of loperamide hydrochloride.

International journal of pharmaceutics 20040415

[Type 1 Gaucher's disease in the adult. Nutritional management during initiation of treatment with miglustat].

Presse medicale (Paris, France : 1983) 20040410

Signals in the activation of opioid mu-receptors by loperamide to enhance glucose uptake into cultured C2C12 cells.

Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20040401

Anaphylaxis due to loperamide.

Allergy 20040301

Yogic versus conventional treatment in diarrhea-predominant irritable bowel syndrome: a randomized control study.

Applied psychophysiology and biofeedback 20040301

Variable modulation of opioid brain uptake by P-glycoprotein in mice.

Biochemical pharmacology 20040115

Loperamide toxicity in a collie with the MDR1 mutation associated with ivermectin sensitivity.

Journal of veterinary internal medicine 20040101

Treatment of travelers' diarrhea among Austrian tourists.

Journal of travel medicine 20040101

Loperamide modifies the tissue disposition kinetics of ivermectin in rats.

The Journal of pharmacy and pharmacology 20040101

The clinical and pathologic significance of microscopic colitis.

Journal of clinical gastroenterology 20040101

The effect of two antidiarrhoeal drugs on the psychosocial adjustment to illness in chronic functional diarrhoea.

Romanian journal of internal medicine = Revue roumaine de medecine interne 20040101

Reduction of saquinavir exposure by coadministration of loperamide: a two-way pharmacokinetic interaction.

Clinical pharmacokinetics 20040101

Lethal gastroenteritis associated with clozapine and loperamide.

The American journal of psychiatry 20031201

Gastroenteritis in children.

Clinical evidence 20031201

Irritable bowel syndrome.

The New England journal of medicine 20031127

Potential roles of P-gp and calcium channels in loperamide and diphenoxylate transport.

Toxicology and applied pharmacology 20031115

Effects of ABCB1 (multidrug resistance transporter) gene mutations on disposition and central nervous effects of loperamide in healthy volunteers.

Pharmacogenetics 20031101

No effect of MDR1 C3435T variant on loperamide disposition and central nervous system effects.

Clinical pharmacology and therapeutics 20031101

Development of tolerance to the inhibitory effect of loperamide on gastrointestinal transit in mice.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20031101

Management of acute cancer treatment-induced diarrhea.

Seminars in oncology nursing 20031101

Loperamide increases glucose ultilization in streptozotocin-induced diabetic rats.

Clinical and experimental pharmacology & physiology 20031001

Chronic diarrhoea in HIV-1-infected adults in Nairobi, Kenya: evaluation of risk factors and the WHO treatment algorithm.

AIDS (London, England) 20030926

[Current and future prospects of the treatment of the irritable bowel syndrome].

Revista clinica espanola 20030901

Analgesic action of loperamide, an opioid agonist, and its blocking action on voltage-dependent Ca2+ channels.

Neuroscience research 20030801

Loperamide suppositories in an adolescent with childhood-onset functional non-retentive fecal soiling.

Journal of pediatric gastroenterology and nutrition 20030801

Sodium pentobarbital anesthesia transiently enhances the severity of infection following intragastric, but not intravenous, inoculation of Listeria monocytogenes in mice.

Microbial pathogenesis 20030801

Watermelon colon: case report and review.

Gastrointestinal endoscopy 20030701

Evaluation of different calorimetric methods to determine the glass transition temperature and molecular mobility below T(g) for amorphous drugs.

International journal of pharmaceutics 20030618

Drug complexation, in vitro release and cellular entry of dendrimers and hyperbranched polymers.

International journal of pharmaceutics 20030618

[Malaria--case report].

Deutsche medizinische Wochenschrift (1946) 20030606

Peripheral opioids act as analgesics in bone cancer pain in mice.

Neuroreport 20030506

Suspicion of microscopic colitis raised by sonographic examination.

Journal of clinical ultrasound : JCU 20030501

Loperamide mobilizes intracellular Ca2+ stores in insulin-secreting HIT-T15 cells.

British journal of pharmacology 20030501

I get occasional diarrhea. Is there anything nonprescription that's particularly effective for that?

Mayo Clinic health letter (English ed.) 20030501

[Ileus after the use of loperamide in a child with acute diarrhea].

Nederlands tijdschrift voor geneeskunde 20030405

Antidiarrhoeal activity of hot water extract of black tea (Camellia sinensis).

Phytotherapy research : PTR 20030401

Effect of loperamide on gastro-oesophageal reflux.

Scandinavian journal of gastroenterology 20030401

Dose-response relationship and mechanism of action of Saccharomyces boulardii in castor oil-induced diarrhea in rats.

Digestive diseases and sciences 20030401

Racecadotril versus loperamide: antidiarrheal research revisited.

Digestive diseases and sciences 20030201

Morphine and d-amphetamine nullify each others' hypothermic effects in mice.

Pharmacology & toxicology 20030201

Potentiation of the antiproliferative activity of MKT-077 by loperamide, diltiazem and tamoxifen.

Oncology reports 20030101

Effects of full-thickness burns on nociceptor sensitization in anesthetized rats.

Burns : journal of the International Society for Burn Injuries 20021201

Acute gastroenteritis in children.

Clinical evidence 20021201

Spreading depression: imaging and blockade in the rat neocortical brain slice.

Journal of neurophysiology 20021101

Evidence-based position statement on the management of irritable bowel syndrome in North America.

The American journal of gastroenterology 20021101

Systematic review on the management of irritable bowel syndrome in North America.

The American journal of gastroenterology 20021101

Antipruritic and antihyperalgesic actions of loperamide and analogs.

Life sciences 20021025

Antidiarrhoeal activity of seed extract of Albizzia lebbeck Benth.

Phytotherapy research : PTR 20020901

[Travellers' acute diarrhea].

Revue medicale de la Suisse romande 20020901

[Taking charge of adult's anal incontinence].

Revue medicale de la Suisse romande 20020901

A multinational comparison of racecadotril and loperamide in the treatment of acute watery diarrhoea in adults.

Scandinavian journal of gastroenterology 20020601

Acute gastroenteritis in children.

Clinical evidence 20020601

Short bowel syndrome: a nutritional and medical approach.

CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20020514

Fecal incontinence in anorectal malformations, neuropathy, and miscellaneous conditions.

Seminars in pediatric surgery 20020501

Advice for travelers.

The Medical letter on drugs and therapeutics 20020415

Spinal and peripheral mu opioids and the development of secondary tactile allodynia after thermal injury.

Anesthesia and analgesia 20020401

Interaction of morphine, fentanyl, sufentanil, alfentanil, and loperamide with the efflux drug transporter P-glycoprotein.

Anesthesiology 20020401

Urinary retention with loperamide.

Prescrire international 20020401

Loperamide-induced enhancement of moxidectin availability in cattle.

Journal of veterinary pharmacology and therapeutics 20020401

Comparison of the peripheral and central effects of the opioid agonists loperamide and morphine in the formalin test in rats.

Neuropharmacology 20020201

Determination of the active ingredient loperamide hydrochloride in pharmaceutical caplets by high performance thin layer chromatography with ultraviolet absorption densitometry of fluorescence quenched zones.

Acta poloniae pharmaceutica 20020101

Efficacy of prophylactic anti-diarrhoeal treatment in patients receiving Campto for advanced colorectal cancer.

Anticancer research 20020101

Effects of yogurt supplemented with brewer's yeast cell wall on constipation and intestinal microflora in rats.

Journal of nutritional science and vitaminology 20011201

Ritonavir increases loperamide plasma concentrations without evidence for P-glycoprotein involvement.

Clinical pharmacology and therapeutics 20011101

From hit to lead. Combining two complementary methods for focused library design. Application to mu opiate ligands.

Journal of medicinal chemistry 20011011

Clinical evaluation and management of acute infectious diarrhea in adults.

Gastroenterology clinics of North America 20010901

Traveler's diarrhea.

Gastroenterology clinics of North America 20010901

[Colonic microflora and motility. Physiological data and during irritable bowel syndrome].

Gastroenterologie clinique et biologique 20010901

Effects of loperamide and other opioid-related substances on the transcriptional regulation of the rat pro-opiomelanocortin gene in AtT20 cells.

Neuroendocrinology 20010801

Increase of opioid mu-receptor gene expression in streptozotocin-induced diabetic rats.

Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20010801

Recent concepts in fecal incontinence.

Current women's health reports 20010801

[What is effective in traveler's diarrhea? Current recommendations on prevention, therapy and after care].

MMW Fortschritte der Medizin 20010719

A scintigraphic study to investigate the potential for altered gut distribution of loperamide from a loperamide-simethicone formulation in man.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20010701

Antisecretory effect of loperamide in colon epithelial cells by inhibition of basolateral K+ conductance.

Scandinavian journal of gastroenterology 20010701

[Loperamide abuse in anxiety disorder].

Der Nervenarzt 20010701

Sulfated polysaccharides, but not cellulose, increase colonic mucus in rats with loperamide-induced constipation.

Digestive diseases and sciences 20010701

Guidelines for adults on self-medication for the treatment of acute diarrhoea.

Alimentary pharmacology & therapeutics 20010601

Control of irinotecan-induced diarrhea by octreotide after loperamide failure.

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20010601

[Travelers' diarrhea].

Therapeutische Umschau. Revue therapeutique 20010601

Does loperamide affect motor activity after proctocolectomy and ileal pouch-anal anastomosis? An experimental study in dogs.

International journal of colorectal disease 20010601

Early pregnancy termination with vaginal misoprostol combined with loperamide and acetaminophen prophylaxis.

Contraception 20010401

Effects of brewer's yeast cell wall on constipation and defecation in experimentally constipated rats.

Bioscience, biotechnology, and biochemistry 20010401

Management of the irritable bowel syndrome.

Gastroenterology 20010201

Drug transporters revisited.

Journal of clinical psychopharmacology 20010201

Optimal dosing of ofloxacin with loperamide in the treatment of non-dysenteric travelers' diarrhea.

Journal of travel medicine 20010101

The role of cannabinoid receptors in intestinal motility, defaecation and diarrhoea in rats.

European journal of pharmacology 19991112

Herbal medicines as a factor in delirium.

Psychiatric services (Washington, D.C.) 19990701

Effect of the 5-hydroxytryptamine3 (5-HT3)-receptor antagonist KB-R6933 on experimental diarrhea models.

Japanese journal of pharmacology 19990501

Role of tachykinins in castor oil diarrhoea in rats.

British journal of pharmacology 19970501

Antidiarrhoeal activity of new thiazolidinones related to loperamide.

The Journal of pharmacy and pharmacology 19960701

Difenoxin and loperamide: studies on possible mechanisms of intestinal antisecretory action.

Naunyn-Schmiedeberg's archives of pharmacology 19930201

Toxic delirium possibly caused by loperamide.

The Journal of pediatrics 19910401

Naloxone-reversible antidiarrheal effects of enkephalinase inhibitors.

European journal of pharmacology 19871201

Loperamide toxicity in severe protracted diarrhoea.

Archives of disease in childhood 19830701

[Neurological symptoms precipitated by loperamide (author's transl)].

Anales espanoles de pediatria 19801201

In vivo antimotility and antidiarrheal activity of lidamidine hydrochloride (WHR-1142A), a novel antidiarrheal agent. Comparison with diphenoxylate and loperamide.

Arzneimittel-Forschung 19780101