L-778123 hydrochloride
Title | Journal |
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Modulation of anthracycline-induced cytotoxicity by targeting the prenylated proteome in myeloid leukemia cells. | Journal of molecular medicine (Berlin, Germany) 20120201 |
ErbB-2 blockade and prenyltransferase inhibition alter epidermal growth factor and epidermal growth factor receptor trafficking and enhance (111)In-DTPA-hEGF Auger electron radiation therapy. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20110501 |
A tagging-via-substrate approach to detect the farnesylated proteome using two-dimensional electrophoresis coupled with Western blotting. | Molecular & cellular proteomics : MCP 20100401 |
Development of farnesyl transferase inhibitors: a review. | The oncologist 20050901 |
Isoprenylation of intracellular proteins as a new target for the therapy of human neoplasms: preclinical and clinical implications. | Current drug targets 20050501 |
[Farnesyltransferase inhibitors: preliminary results in acute myeloid leukemia]. | Bulletin du cancer 20050301 |
Inhibition of lymphocyte activation and function by the prenylation inhibitor L-778,123. | Investigational new drugs 20050101 |
Crystallographic analysis reveals that anticancer clinical candidate L-778,123 inhibits protein farnesyltransferase and geranylgeranyltransferase-I by different binding modes. | Biochemistry 20040720 |
Farnesyl transferase inhibitors for patients with lung cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20040615 |
[Ras signaling pathway as a target for farnesyltransferase inhibitors--a new, promising prospects in the treatment for malignant disorders]. | Wiadomosci lekarskie (Warsaw, Poland : 1960) 20040101 |
Farnesyltransferase inhibitors are potent lung cancer chemopreventive agents in A/J mice with a dominant-negative p53 and/or heterozygous deletion of Ink4a/Arf. | Oncogene 20030918 |
Farnesyltransferase inhibitors as radiation sensitizers. | International journal of radiation biology 20030701 |
Farnesyl transferase inhibitors in the treatment of breast cancer. | Expert opinion on investigational drugs 20030301 |
The effects of the farnesyl transferase inhibitor FTI L-778,123 on normal, myelodysplastic, and myeloid leukemia bone marrow progenitor proliferation in vitro. | Leukemia & lymphoma 20030101 |
Farnesyl transferase inhibitors as anticancer agents. | European journal of cancer (Oxford, England : 1990) 20020901 |
A phase I and pharmacological study of the farnesyl protein transferase inhibitor L-778,123 in patients with solid malignancies. | Clinical cancer research : an official journal of the American Association for Cancer Research 20011201 |
Ras inhibitors and radiation therapy. | Seminars in radiation oncology 20011001 |
Farnesyltransferase inhibitors. | Seminars in oncology 20011001 |
Anions modulate the potency of geranylgeranyl-protein transferase I inhibitors. | The Journal of biological chemistry 20010706 |
High-performance liquid chromatography/mass spectrometry characterization of Ki4B-Ras in PSN-1 cells treated with the prenyltransferase inhibitor L-778,123. | Analytical biochemistry 20010301 |