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Home Other Building Blocks Hyodeoxycholic acid sodium salt

Hyodeoxycholic acid sodium salt

CAS No.:
10421-49-5
Catalog Number:
AG003QZ8
Molecular Formula:
C24H39NaO4
Molecular Weight:
414.5538
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5g
98%
In Stock USA
United States
$57
- +
25g
98%
In Stock USA
United States
$144
- +
100g
98%
In Stock USA
United States
$460
- +
Product Description
Catalog Number:
AG003QZ8
Chemical Name:
Hyodeoxycholic acid sodium salt
CAS Number:
10421-49-5
Molecular Formula:
C24H39NaO4
Molecular Weight:
414.5538
MDL Number:
MFCD00079342
IUPAC Name:
sodium;(4R)-4-[(3R,5R,6S,8S,9S,10R,13R,14S,17R)-3,6-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoate
InChI:
InChI=1S/C24H40O4.Na/c1-14(4-7-22(27)28)17-5-6-18-16-13-21(26)20-12-15(25)8-10-24(20,3)19(16)9-11-23(17,18)2;/h14-21,25-26H,4-13H2,1-3H3,(H,27,28);/q;+1/p-1/t14-,15-,16+,17-,18+,19+,20+,21+,23-,24-;/m1./s1
InChI Key:
DUYSCILLIVEITB-ADQIWYCWSA-M
SMILES:
O[C@@H]1CC[C@]2([C@@H](C1)[C@@H](O)C[C@@H]1[C@@H]2CC[C@]2([C@H]1CC[C@@H]2[C@@H](CCC(=O)[O-])C)C)C.[Na+]
UNII:
HBY71R8HO2
Properties
Complexity:
612  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
10  
Defined Bond Stereocenter Count:
0
Exact Mass:
414.275g/mol
Formal Charge:
0
Heavy Atom Count:
29  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
414.562g/mol
Monoisotopic Mass:
414.275g/mol
Rotatable Bond Count:
4  
Topological Polar Surface Area:
80.6A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Literature
Title Journal
BASIC--a bile acid-sensitive ion channel highly expressed in bile ducts. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20121001
A tandem mass spectrometric study of bile acids: interpretation of fragmentation pathways and differentiation of steroid isomers. Steroids 20120201
Improved analysis of bile acids in tissues and intestinal contents of rats using LC/ESI-MS. Journal of lipid research 20090101
The inhibitory effects of cholalic acid and hyodeoxycholalic acid on the expression of TNFalpha and IL-1beta after cerebral ischemia in rats. Archives of pharmacal research 20090101
Novel polymorphic human UDP-glucuronosyltransferase 2A3: cloning, functional characterization of enzyme variants, comparative tissue expression, and gene induction. Molecular pharmacology 20080901
[Determination of chyodeoxycholic acid in Bile Arisaema by HPLC-ELSD]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070801
Simultaneous determination of geniposide, baicalin, cholic acid and hyodeoxycholic acid in rat serum for the pharmacokinetic investigations by high performance liquid chromatography-tandem mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060914
Mice lacking Mrp3 (Abcc3) have normal bile salt transport, but altered hepatic transport of endogenous glucuronides. Journal of hepatology 20060401
Enzymatic production of bile Acid glucuronides used as analytical standards for liquid chromatography-mass spectrometry analyses. Molecular pharmaceutics 20060101
Resistance to ursodeoxycholic acid-induced growth arrest can also result in resistance to deoxycholic acid-induced apoptosis and increased tumorgenicity. BMC cancer 20060101
[Study on extraction technique of HDCA]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20040501
Steroids in the intestinal tract of rats are affected by dietary-fibre-rich barley-based diets. The British journal of nutrition 20031101
Glucosidation of hyodeoxycholic acid by UDP-glucuronosyltransferase 2B7. Biochemical pharmacology 20030201
[Study on effect of qingkailing injection and its active principle in inducing cell apoptosis in human acute promyelocytic leukemia]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20011101
Hyodeoxycholic acid efficiently suppresses atherosclerosis formation and plasma cholesterol levels in mice. Journal of lipid research 20010801
Hydrophilic and hydrophobic bile acids exhibit different cytotoxicities through cytolysis, interleukin-8 synthesis and apoptosis in the intestinal epithelial cell lines. IEC-6 and Caco-2 cells. Scandinavian journal of gastroenterology 20010501
Isolation and characterization of hyodeoxycholic-acid: UDP-glucuronosyltransferase from human liver. European journal of biochemistry 19910901
Properties