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Heptan-1-ol

CAS No.:
111-70-6
Catalog Number:
AG003QUY
Molecular Formula:
C7H16O
Molecular Weight:
116.2013
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Purity
Availability
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Product Description
Catalog Number:
AG003QUY
Chemical Name:
Heptan-1-ol
CAS Number:
111-70-6
Molecular Formula:
C7H16O
Molecular Weight:
116.2013
MDL Number:
MFCD00002986
IUPAC Name:
heptan-1-ol
InChI:
InChI=1S/C7H16O/c1-2-3-4-5-6-7-8/h8H,2-7H2,1H3
InChI Key:
BBMCTIGTTCKYKF-UHFFFAOYSA-N
SMILES:
CCCCCCCO
UNII:
8JQ5607IO5
NSC Number:
3703
FEMA Number:
2548
RTECS Number:
MK0350000
UN Number:
2810
Properties
Complexity:
35.4  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
116.12g/mol
Formal Charge:
0
Heavy Atom Count:
8  
Hydrogen Bond Acceptor Count:
1  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
116.204g/mol
Monoisotopic Mass:
116.12g/mol
Rotatable Bond Count:
5  
Topological Polar Surface Area:
20.2A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
2.7  
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Protective effect of gap junction uncouplers given during hypoxia against reoxygenation injury in isolated rat hearts. American journal of physiology. Heart and circulatory physiology 20060201
P2X7 receptors mediate ATP release and amplification of astrocytic intercellular Ca2+ signaling. The Journal of neuroscience : the official journal of the Society for Neuroscience 20060201
Effect of heptanol on noradrenaline-induced contractions in rat vas deferens. Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi 20060201
Effects of heptanol on neurogenic contractions of vas deferens: A comparative study of stimulation frequency in guinea pig and rat. The journal of physiological sciences : JPS 20060201
Gap junction-mediated intercellular communication between dendritic cells (DCs) is required for effective activation of DCs. Journal of immunology (Baltimore, Md. : 1950) 20060101
Gap junctions mediate glucose transport between GLUT1-positive and -negative cells in the spiral limbus of the rat cochlea. Cell communication & adhesion 20060101
Display of a thermostable lipase on the surface of a solvent-resistant bacterium, Pseudomonas putida GM730, and its applications in whole-cell biocatalysis. BMC biotechnology 20060101
Electrotonic transmission within pericyte-containing retinal microvessels. Microcirculation (New York, N.Y. : 1994) 20060101
MD simulations of the binding of alcohols and diols by a calixarene in water: connections between microscopic and macroscopic properties. The journal of physical chemistry. B 20051215
The hyperfluidization of mammalian cell membranes acts as a signal to initiate the heat shock protein response. The FEBS journal 20051201
[Effects and the mechanism of carvedilol on gap junctional intercellular communication in rat myocardium]. Zhonghua xin xue guan bing za zhi 20051201
Pretreatment with D-myo-inositol trisphosphate reduces infarct size in rabbit hearts: role of inositol trisphosphate receptors and gap junctions in triggering protection. The Journal of pharmacology and experimental therapeutics 20050901
Surface contact measurement of electrical cell uncoupling in the mouse heart during ischemia. Bioelectrochemistry (Amsterdam, Netherlands) 20050901
Adsorption of bituminous components at oil/water interfaces investigated by quartz crystal microbalance: implications to the stability of water-in-oil emulsions. Langmuir : the ACS journal of surfaces and colloids 20050830
Delayed uncoupling contributes to the protective effect of heptanol against ischaemia in the rat isolated heart. Clinical and experimental pharmacology & physiology 20050801
Interactions between acetoin, a plant volatile, and pheromone in Rhynchophorus palmarum: behavioral and olfactory neuron responses. Journal of chemical ecology 20050801
[The effect of gap blocker 1-heptanol on function and morphology of guinea pig cochlea]. Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology 20050801
The potential role of gap junction communication between cumulus cells and bovine oocytes during in vitro maturation. Molecular reproduction and development 20050701
Improved vacuum-UV (VUV)-initiated photomineralization of organic compounds in water with a xenon excimer flow-through photoreactor (Xe2* lamp, 172 nm) containing an axially centered ceramic oxygenator. Chemosphere 20050701
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk). Journal of medicinal chemistry 20050505
Insulin-like growth factor-I induces oocyte maturational competence but not meiotic resumption in white bass (Morone chrysops) follicles in vitro: evidence for rapid evolution of insulin-like growth factor action. Biology of reproduction 20050501
Biocompatibility of a nonpenetrating synthetic cornea in vascularized rabbit corneas. Cornea 20050501
Partitioning behavior of Alkan-1-ols between milkfat and aqueous phases as influenced by temperature. Journal of agricultural and food chemistry 20050406
Lipid-mediated delivery of brain-specific angiogenesis inhibitor 1 gene reduces corneal neovascularization in an in vivo rabbit model. Gene therapy 20050401
The effect of extracellular calcium concentration on calcium-mediated cell signaling in NF1 tumor suppressor-deficient keratinocytes. Archives of dermatological research 20050401
Cells of Candida utilis for in vitro (R)-phenylacetylcarbinol production in an aqueous/octanol two-phase reactor. Biotechnology letters 20050401
Gap junction coupling and apoptosis in GFSHR-17 granulosa cells. The Journal of membrane biology 20050401
Prediction of solvents extraction-the organochlorine pesticides in soil using solubility parameter. Talanta 20050331
Effects of functional group position on spatial representations of aliphatic odorants in the rat olfactory bulb. The Journal of comparative neurology 20050307
Aroma analysis of light-exposed milk stored with and without natural and synthetic antioxidants. Journal of dairy science 20050301
The aggregation pheromone of Diorhabda elongata, a biological control agent of saltcedar (Tamarix spp.): identification of two behaviorally active components. Journal of chemical ecology 20050301
Photodynamic therapy with PhotoPoint photosensitiser MV6401, indium chloride methyl pyropheophorbide, achieves selective closure of rat corneal neovascularisation and rabbit choriocapillaris. The British journal of ophthalmology 20050101
Influence of dietary solvents on strength of nanofill and ormocer composites. Operative dentistry 20050101
Determination of low molecular weight alcohols including fusel oil in various samples by diethyl ether extraction and capillary gas chromatography. Journal of AOAC International 20050101
The Effects of Heptanol on Electrical Coupling during Ischemia in the Perfused Isolated Rat Heart. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference 20050101
Complex formation of copper(II) and iron(II) with octadecyloxythiazolylazophenol at the heptane-water interface. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20041101
cAMP inhibits transepithelial chloride secretion across bovine ciliary body/epithelium. Investigative ophthalmology & visual science 20041001
Structural calorimetry of main transition of supported DMPC bilayers by temperature-controlled AFM. Biophysical journal 20041001
Endocochlear potential and endolymphatic K+ changes induced by gap junction blockers. Acta oto-laryngologica 20041001
Organization of four thermotropic liquid crystals of different polarities on model liquid and solid surfaces. Langmuir : the ACS journal of surfaces and colloids 20040914
Enhanced effect of gap junction uncouplers on macroscopic electrical properties of reperfused myocardium. The Journal of physiology 20040815
Gap junctions are required for trophoblast proliferation in early human placental development. Placenta 20040801
Electrical propagation in synthetic ventricular myocyte strands from germline connexin43 knockout mice. Circulation research 20040723
Interfacial aggregate growth process of Fe(II) and Fe(III) complexes with pyridylazophenol in solvent extraction system. Journal of colloid and interface science 20040715
Functional characterization of Cx43 based gap junctions during spermatogenesis. Journal of cellular physiology 20040701
In vivo time-lapse imaging in medaka--n-heptanol blocks contractile rhythmical movements. Mechanisms of development 20040701
Junctional and nonjunctional effects of heptanol and glycyrrhetinic acid derivates in rat mesenteric small arteries. British journal of pharmacology 20040701
Homogeneous nucleation rates of higher n-alcohols measured in a laminar flow diffusion chamber. The Journal of chemical physics 20040622
The nature of the hydrophobic n-alkanol binding site within the C1 domains of protein kinase Calpha. Biochemistry 20040615
Behaviour of dehydrated baker's yeast during reduction reactions in a biphasic medium. Applied microbiology and biotechnology 20040601
Electron microprobe analysis of ouabain-exposed ciliary epithelium: PE-NPE cell couplets form the functional units. American journal of physiology. Cell physiology 20040601
Effects of alcohols and anesthetics on recombinant voltage-gated Na+ channels. The Journal of pharmacology and experimental therapeutics 20040601
Conductive and kinetic properties of connexin45 hemichannels expressed in transfected HeLa cells. The Journal of membrane biology 20040601
Spatially and temporally distinct expression of fibroblast connexins after sheep ventricular infarction. Cardiovascular research 20040501
[Repellent effect of volatile oil from whitefly (Syngonium podophyllum) on aphids and its chemical constituents]. Ying yong sheng tai xue bao = The journal of applied ecology 20040501
Effect of alcohol addition to the aqueous phase on the thermal effects of micellization of cationic benzyldimethyldodecylammonium bromide and its adsorption onto porous and nonporous silicas. Journal of colloid and interface science 20040415
An HPLC-MS approach for analysis of very long chain fatty acids and other apolar compounds on octadecyl-silica phase using partly miscible solvents. Analytical chemistry 20040401
Comparison of the olfactory sensitivity of two sympatric steppe grasshopper species (Orthoptera: Acrididae) to plant volatile compounds. Science in China. Series C, Life sciences 20040401
General anesthetic octanol and related compounds activate wild-type and delF508 cystic fibrosis chloride channels. British journal of pharmacology 20040301
Synthesis and biological activity of the four stereoisomers of 4-methyl-3-heptanol: main component of the aggregation pheromone of Scolytus amygdali. Journal of chemical ecology 20040301
Protective role of gap junctions in preconditioning against myocardial infarction. American journal of physiology. Heart and circulatory physiology 20040101
Hydrogen peroxide increases gap junctional communication and induces astrocyte toxicity: regulation by brain macrophages. Glia 20040101
Direct determination of unbound lipophilic ligands in aqueous solutions. Biological procedures online 20040101
Short-term effects and teratogenicity of heptanol on embryos of Xenopus laevis. Environmental toxicology and pharmacology 20040101
Behavior of ectopic surface: effects of beta-adrenergic stimulation and uncoupling. American journal of physiology. Heart and circulatory physiology 20031201
Requirement of gap junctional intercellular communication for human villous trophoblast differentiation. Biology of reproduction 20031101
A novel form of cellular communication among thymic epithelial cells: intercellular calcium wave propagation. American journal of physiology. Cell physiology 20031101
The metabolic inhibitor antimycin A can disrupt cell-to-cell communication by an ATP- and Ca(2+)-independent mechanism. Pflugers Archiv : European journal of physiology 20031101
Aggregation and solubility behavior of asphaltenes and their subfractions. Journal of colloid and interface science 20031101
Coupling between sensory neurons in the olfactory epithelium. Chemical senses 20031101
An investigation of chemotaxis in the insect parasitic nematode Heterorhabditis bacteriophora. Parasitology 20031001
Quantitative structure-fungitoxicity relationships of some monohydric alcohols. Journal of agricultural and food chemistry 20030827
A mutation in transmembrane domain II of the 5-hydroxytryptamine(3A) receptor stabilizes channel opening and alters alcohol modulatory actions. The Journal of pharmacology and experimental therapeutics 20030801
Human diabetic corneas preserve wound healing, basement membrane, integrin and MMP-10 differences from normal corneas in organ culture. Experimental eye research 20030801
Fiber orientation and cell-cell coupling influence ventricular fibrillation dynamics. Journal of cardiovascular electrophysiology 20030801
Regional gap junction inhibition increases defibrillation thresholds. American journal of physiology. Heart and circulatory physiology 20030701
In situ Ca2+ imaging of odor responses in a coronal olfactory epithelium slice. Neuroreport 20030611
Ion-exclusion chromatographic behavior of aliphatic carboxylic acids and benzenecarboxylic acids on a sulfonated styrene--divinylbenzene co-polymer resin column with sulfuric acid containing various alcohols as eluent. Journal of chromatography. A 20030516
Intercellular calcium waves in cultured enteric glia from neonatal guinea pig. Glia 20030501
Increased connexin43-mediated intercellular communication in a rat model of bladder overactivity in vivo. American journal of physiology. Regulatory, integrative and comparative physiology 20030501
Functional hemichannels in astrocytes: a novel mechanism of glutamate release. The Journal of neuroscience : the official journal of the Society for Neuroscience 20030501
Preparative separation and purification of squalene from the microalga Thraustochytrium ATCC 26185 by high-speed counter-current chromatography. Journal of chromatography. A 20030425
Disposition of short-chain aliphatic alcohols in rabbit vitreous by ocular microdialysis. Experimental eye research 20030301
Study of light-induced volatile compounds in goat's milk cheese. Journal of agricultural and food chemistry 20030226
Cell density and growth-dependent down-regulation of both intracellular calcium responses to agonist stimuli and expression of smooth-surfaced endoplasmic reticulum in MC3T3-E1 osteoblast-like cells. The Journal of biological chemistry 20030221
Relationship between molecular structure, concentration and odor qualities of oxygenated aliphatic molecules. Chemical senses 20030101
Blockade of brain stem gap junctions increases phrenic burst frequency and reduces phrenic burst synchronization in adult rat. Journal of neurophysiology 20030101
[Metabolic disorders and their correction in petrochemical production workers exposed to heptyl]. Meditsina truda i promyshlennaia ekologiia 20030101
Role for gap junctional intercellular communications in wound repair. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 20030101
Short term effects of dietary medium-chain fatty acids and n-3 long-chain polyunsaturated fatty acids on the fat metabolism of healthy volunteers. Lipids in health and disease 20030101
The complex dielectric spectrum of heart tissue during ischemia. Bioelectrochemistry (Amsterdam, Netherlands) 20021201
Inhibitors of gap junctions attenuate myogenic tone in cerebral arteries. American journal of physiology. Heart and circulatory physiology 20021201
Induction of Oct-3/4 expression in somatic cells by gap junction-mediated cAMP signaling from blastomeres. European journal of cell biology 20021101
Amiloride-sensitive sodium current in everted Ambystoma initial collecting tubule: short-term insulin effects. American journal of physiology. Cell physiology 20021001
Response of thyroid follicular cells to gamma irradiation compared to proton irradiation: II. The role of connexin 32. Radiation research 20021001
Pilot study on the time course of apoptosis in the regenerating corneal epithelium. Acta ophthalmologica Scandinavica 20021001
Increased vulnerability to inducible atrial fibrillation caused by partial cellular uncoupling with heptanol. American journal of physiology. Heart and circulatory physiology 20020901
Desynchronising effect of the endothelium on intracellular Ca2+ concentration dynamics in vascular smooth muscle cells of rat mesenteric arteries. Cell calcium 20020901
[Corneal burns and matrix metalloproteinases (MMP-2 and -9): the effects of human amniotic membrane transplantation]. Journal francais d'ophtalmologie 20020901
Patterns of intracellular and intercellular Ca2+ waves in the longitudinal muscle layer of the murine large intestine in vitro. The Journal of physiology 20020815
Role of mesangial cells and gap junctions in tubuloglomerular feedback. Kidney international 20020801
Coordination of mesangial cell contraction by gap junction--mediated intercellular Ca(2+) wave. Journal of the American Society of Nephrology : JASN 20020801
Factors affecting outcome following transplantation of ex vivo expanded limbal epithelium on amniotic membrane for total limbal deficiency in rabbits. Investigative ophthalmology & visual science 20020801
Gap junction uncoupling protects the heart against ischemia. The Journal of thoracic and cardiovascular surgery 20020801
Aging-related increase to inducible atrial fibrillation in the rat model. Journal of cardiovascular electrophysiology 20020801
Pheromone-based trapping of West Indian sugarcane weevil in a sugarcane plantation. Journal of chemical ecology 20020801
Molecular design of antifungal agents. Journal of agricultural and food chemistry 20020703
Catalytic properties of alcohol acyltransferase in different strawberry species and cultivars. Journal of agricultural and food chemistry 20020703
Olfactory sensitivity for aliphatic alcohols in squirrel monkeys and pigtail macaques. The Journal of experimental biology 20020601
Activation and inhibition of the transduction process in silkmoth olfactory receptor neurons. Chemical senses 20020601
Vascular regulation of type II cell exocytosis. American journal of physiology. Lung cellular and molecular physiology 20020501
Pressure-induced endothelial Ca(2+) oscillations in lung capillaries. American journal of physiology. Lung cellular and molecular physiology 20020501
trans-6-Aminocyclohept-3-enols, a new designed polyfunctionalized chiral building block for the asymmetric synthesis of 2-substituted-4-hydroxypiperidines. Organic letters 20020418
Spontaneous rhythmicity in cultured cell clusters isolated from mouse small intestine. The Japanese journal of physiology 20020401
A comparison of lipase-catalysed ester and lactone synthesis in low-water systems: analysis of optimum water activity. Biotechnology and bioengineering 20020320
Detection and quantification of ochratoxin A and deoxynivalenol in barley grains by GC-MS and electronic nose. International journal of food microbiology 20020205
Spiral wave generation in heterogeneous excitable media. Physical review letters 20020204
Thymosin beta 4 promotes corneal wound healing and decreases inflammation in vivo following alkali injury. Experimental eye research 20020201
The gap junction uncoupler heptanol abrogates infarct size reduction with preconditioning in mouse hearts. Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology 20020101
Dual functions for connexins: Cx43 regulates growth independently of gap junction formation. Experimental cell research 20011210
Activation of connexin-43 hemichannels can elevate [Ca(2+)]i and [Na(+)]i in rabbit ventricular myocytes during metabolic inhibition. Journal of molecular and cellular cardiology 20011201
Growth factors but not gap junctions play a role in injury-induced Ca2+ waves in epithelial cells. Journal of cell science 20011201
Bending the MDCK cell primary cilium increases intracellular calcium. The Journal of membrane biology 20011101
A spontaneously arising mutation in connexin32 with repeated passage of FRTL-5 cells coincides with increased growth rate and reduced thyroxine release. Journal of molecular endocrinology 20011001
Involvement of connexin 43 in meiotic maturation of bovine oocytes. Reproduction (Cambridge, England) 20011001
Gap junction blockers decrease defibrillation thresholds without changes in ventricular refractoriness in isolated rabbit hearts. Circulation 20010925
Can gap-junction blockade preferentially inhibit neuronal hypersynchrony vs. excitability? Neuropharmacology 20010901
Optical measurement of cell-to-cell coupling in intact heart using subthreshold electrical stimulation. American journal of physiology. Heart and circulatory physiology 20010801
Temporal profile of total, bound, and free Gc-globulin after acetaminophen overdose. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20010801
Gating properties of gap junction channels assembled from connexin43 and connexin43 fused with green fluorescent protein. Biophysical journal 20010701
Straight-chain alcohols exhibit a cutoff in potency for the inhibition of recombinant glutamate receptor subunits. British journal of pharmacology 20010701
Blocking AMPA receptor desensitization prolongs spontaneous EPSC decay times and depolarizes H1 horizontal cells in carp retinal slices. Neuroscience research 20010701
Application of zirconium-modified silica gel as a stationary phase in the ion-exclusion chromatography of carboxylic acids. II. Separation of aliphatic carboxylic acids with pyromellitic acid as eluent and with suppressed conductimetric detection. Journal of chromatography. A 20010622
In vitro hormone induction of final oocyte maturation in striped bass (Morone saxatilis) follicles is inhibited by blockers of phosphatidylinositol 3-kinase activity. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20010601
The epidermal growth factor receptor (EGFR): role in corneal wound healing and homeostasis. Experimental eye research 20010501
Reconstruction of ocular surface with heterologous limbal epithelium and amniotic membrane in a rabbit model. Cornea 20010501
Localized injury in cardiomyocyte network: a new experimental model of ischemia-reperfusion arrhythmias. American journal of physiology. Heart and circulatory physiology 20010401
An accessory role for the diacylglycerol moiety of variable surface glycoprotein of African trypanosomes in the stimulation of bovine monocytes. Veterinary immunology and immunopathology 20010210
Intercellular communication upon mechanical stimulation of CPAE- endothelial cells is mediated by nucleotides. Cell calcium 20010201
Intra- and intercellular Ca(2+)-transient propagation in normal and high glucose solutions in ROS cells during mechanical stimulation. Cell calcium 20010201
Potential of freezing in wastewater treatment: soluble pollutant applications. Water research 20010201
Solvent effect on ion-pair extraction of 2-(2-pyridylazo)-1-naphthol-4-sulfonate anion with solvated hydroxonium ion using alcohols and 1-octanol/octane mixed solvents. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20010201
Increased dilator response to heptanol and octanol in aorta from DOCA-salt-hypertensive rats. Pharmacology 20010101
Pretreatment with the gap junction uncoupler heptanol does not limit infarct size in rabbit heart. Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology 20010101
Connexin-mimetic peptide Gap 27 decreases osteoclastic activity. BMC musculoskeletal disorders 20010101
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