1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-1,8-naphthyridine-3-carboxylic acid sesquihydrate
| Title | Journal |
|---|---|
| Dysregulated miRNA biogenesis downstream of cellular stress and ALS-causing mutations: a new mechanism for ALS. | The EMBO journal 20151103 |
| Enoxacin directly inhibits osteoclastogenesis without inducing apoptosis. | The Journal of biological chemistry 20120518 |
| Rational identification of enoxacin as a novel V-ATPase-directed osteoclast inhibitor. | Current protein & peptide science 20120301 |
| Effect of enoxacin, felbinac, and sparfloxacin on fatty acid metabolism and glucose concentrations in rat tissues. | International journal of toxicology 20110501 |
| Effect of steady-state enoxacin on single-dose pharmacokinetics of roflumilast and roflumilast N-oxide. | Journal of clinical pharmacology 20110401 |
| A simple chromatographic method for determining norfloxacin and enoxacin in pharmacokinetic study assessing CYP1A2 inhibition. | Biomedical chromatography : BMC 20110401 |
| Comparative use of isolated hepatocytes and hepatic microsomes for cytochrome P450 inhibition studies: transporter-enzyme interplay. | Drug metabolism and disposition: the biological fate of chemicals 20101201 |
| Determination of enoxacin and ofloxacin by capillary electrophoresis with electrochemiluminescence detection in biofluids and drugs and its application to pharmacokinetics. | Biomedical chromatography : BMC 20100901 |
| Small molecule modifiers of microRNA miR-122 function for the treatment of hepatitis C virus infection and hepatocellular carcinoma. | Journal of the American Chemical Society 20100616 |
| [Enoxacin for type III A prostatitis: a clinical observation]. | Zhonghua nan ke xue = National journal of andrology 20100301 |
| Simultaneous determination of tetracaine, proline, and enoxacin in human urine by CE with ECL detection. | Journal of chromatographic science 20100101 |
| An application of Ag(III) complex chemiluminescence system for the determination of enoxacin in capsule and biological fluid. | Drug testing and analysis 20100101 |
| Identification of enoxacin as an inhibitor of osteoclast formation and bone resorption by structure-based virtual screening. | Journal of medicinal chemistry 20090827 |
| Elevation of serum gamma-glutamyltranspeptidase activity is frequent in chronic hepatitis C, and is associated with insulin resistance. | Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20090801 |
| Synthesis and biological evaluations of enoxacin carboxamide derivatives. | Archives of pharmacal research 20090701 |
| Evaluation of Pharmasolve corneal permeability enhancement and its irritation on rabbit eyes. | Drug delivery 20090501 |
| Natural history of small gallbladder polyps is benign: evidence from a clinical and pathogenetic study. | The American journal of gastroenterology 20090301 |
| Dysprosium-sensitized chemiluminescence system for the determination of enoxacin in pharmaceutical preparations and biological fluids with flow-injection sampling. | Drug testing and analysis 20090301 |
| Studies of the photooxidant properties of antibacterial fluoroquinolones and their naphthalene derivatives. | Die Pharmazie 20090201 |
| Quantitative comparison of the convulsive activity of combinations of twelve fluoroquinolones with five nonsteroidal antiinflammatory agents. | Drug metabolism and pharmacokinetics 20090101 |
| Enhancement of RNAi by a small molecule antibiotic enoxacin. | Cell research 20081001 |
| Formation of secondary triplet species after excitation of fluoroquinolones in the presence of relatively strong bases. | Journal of the American Chemical Society 20080917 |
| Determination of enoxacin using Tb composite nanoparticles sensitized luminescence method. | Journal of fluorescence 20080901 |
| A small molecule enhances RNA interference and promotes microRNA processing. | Nature biotechnology 20080801 |
| Exploring Mn-doped ZnS quantum dots for the room-temperature phosphorescence detection of enoxacin in biological fluids. | Analytical chemistry 20080515 |
| A rapid CE-potential gradient detection method for determination of quinolones. | Electrophoresis 20071101 |
| Leishmania panamensis: comparative inhibition of nuclear DNA topoisomerase II enzymes from promastigotes and human macrophages reveals anti-parasite selectivity of fluoroquinolones, flavonoids and pentamidine. | Experimental parasitology 20070801 |
| In vitro availability studies of enoxacin in presence of H2 receptor antagonists. | Pakistan journal of pharmaceutical sciences 20070701 |
| [Determination of 16 quinolone residues in animal tissues using high performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry]. | Se pu = Chinese journal of chromatography 20070701 |
| Induction of keratinocyte apoptosis by photosensitizing chemicals plus UVA. | Journal of dermatological science 20070201 |
| Antifungal chemical compounds identified using a C. elegans pathogenicity assay. | PLoS pathogens 20070201 |
| A new approach to quantitative NMR: fluoroquinolones analysis by evaluating the chemical shift displacements. | Journal of pharmaceutical and biomedical analysis 20061011 |
| A batch chemiluminescence determination of enoxacin using a tris-(1,10-phenanthroline)ruthenium(II)-cerium(IV) system. | Journal of fluorescence 20060701 |
| Electrochemiluminescence of terbium (III)-two fluoroquinolones-sodium sulfite system in aqueous solution. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20060501 |
| Effect of fluoroquinolones on plasma glucose levels in fasted and glucose-loaded mice. | Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20060401 |
| T cell-mediated hypersensitivity to quinolones: mechanisms and cross-reactivity. | Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20060101 |
| Effects of Transcutol P on the corneal permeability of drugs and evaluation of its ocular irritation of rabbit eyes. | The Journal of pharmacy and pharmacology 20060101 |
| Preparation and evaluation of sustained ophthalmic gel of enoxacin. | Drug development and industrial pharmacy 20051201 |
| Selective action of fluoroquinolones against intracellular amastigotes of Leishmania (Viannia) panamensis in vitro. | The Journal of parasitology 20051201 |
| [Determination of enoxacin in urine by synchronous fluorimetry]. | Guang pu xue yu guang pu fen xi = Guang pu 20051001 |
| HPLC determination of enoxacin, ciprofloxacin, norfloxacin and ofloxacin with photoinduced fluorimetric (PIF) detection and multiemission scanning: application to urine and serum. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050805 |
| Interaction study between enoxacin and fluvoxamine. | Therapeutic drug monitoring 20050601 |
| Vibrational spectroscopic characterization of fluoroquinolones. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20050501 |
| Antibacterial studies, DNA oxidative cleavage, and crystal structures of Cu(II) and Co(II) complexes with two quinolone family members, ciprofloxacin and enoxacin. | Journal of inorganic biochemistry 20050301 |
| [Simultaneous determination of quinolones in foods by LC/MS/MS]. | Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20041001 |
| Enoxacin trihydrate. | Acta crystallographica. Section C, Crystal structure communications 20040401 |
| Effects of eight antibacterial agents on cell survival and expression of epithelial-cell- or cell-adhesion-related genes in human gingival epithelial cells. | Journal of periodontal research 20040201 |
| Comparative evaluation of antiproliferative activity and induction of apoptosis by some fluoroquinolones with a human non-small cell lung cancer cell line in culture. | Asian Pacific journal of cancer prevention : APJCP 20040101 |
| A randomized controlled trial (volunteer study) of sitafloxacin, enoxacin, levofloxacin and sparfloxacin phototoxicity. | The British journal of dermatology 20031201 |
| Corneal and scleral permeability of quinolones--a pharmacokinetics study. | Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20031201 |
| Synthesis and in vitro antibacterial evaluation of N-[5-(5-nitro-2-thienyl)-1,3,4-thiadiazole-2-yl] piperazinyl quinolones. | European journal of medicinal chemistry 20030901 |
| [Analysis of the response factors of different quinolones detected by evaporative light-scattering detector]. | Yao xue xue bao = Acta pharmaceutica Sinica 20030901 |
| Binding characteristics of fluoroquinolones to synthetic levodopa melanin. | The Journal of pharmacy and pharmacology 20030801 |
| [Synthesis and antibacterial activity of pyridonecarboxylic acid derivatives containing 2-methyl-5-nitroimidazol]. | Yao xue xue bao = Acta pharmaceutica Sinica 20030401 |
| Laser flash photolysis study of photoionization in fluoroquinolones. | Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20021101 |
| The expanding role of fluoroquinolones. | The American journal of medicine 20020708 |
| Spectrophotometric determination of enoxacin as ion-pairs with bromophenol blue and bromocresol purple in bulk and pharmaceutical dosage form. | Journal of pharmaceutical and biomedical analysis 20020701 |
| [Phototoxicity studies of pazufloxacin mesilate, a novel parenteral quinolone antimicrobial agent--in vitro and in vivo studies]. | The Japanese journal of antibiotics 20020601 |
| [Drug interactions between nonsteroidal anti-inflammatory drug and pazufloxacin mesilate, a new quinolone antibacterial agent for intravenous use: convulsions in mice after intravenous or intracerebroventricular administration]. | The Japanese journal of antibiotics 20020601 |
| Osteoadsorptive bisphosphonate derivatives of fluoroquinolone antibacterials. | Journal of medicinal chemistry 20020523 |
| [Terbium sensitized chemiluminescence of enoxacin]. | Yao xue xue bao = Acta pharmaceutica Sinica 20010801 |
| Effect of liposomes and niosomes on skin permeation of enoxacin. | International journal of pharmaceutics 20010521 |
| [Convulsion following the combination of single preoperative oral administration of enoxacine and single postoperative intravenous administration of flurbiprofen axetil]. | Masui. The Japanese journal of anesthesiology 20010401 |
| Selective separation and simultaneous determination of trace levels of five types of fluorinated quinolone drugs by thin-layer chromatography/fluorescence densitometry. | Journal of AOAC International 20010101 |
| Profiles of hepatic and dysrhythmic cardiovascular events following use of fluoroquinolone antibacterials: experience from large cohorts from the Drug Safety Research Unit Prescription-Event Monitoring database. | Drug safety 20010101 |
| Pharmacokinetics of enoxacin and its oxometabolite after multiple oral dosing and penetration into prostatic tissue. | The Journal of antimicrobial chemotherapy 20001201 |
| Role of nitric oxide in the convulsions following the coadministration of enoxacin with fenbufen in mice. | Japanese journal of pharmacology 19980401 |
| Role of nitric oxide in the convulsive seizures induced by fluoroquinolones coadministered with 4-biphenyl acetic acid. | General pharmacology 19971101 |
| Circadian variation in enoxacin-induced convulsions in mice coadministered with fenbufen. | Japanese journal of pharmacology 19970201 |
| Epileptogenic activity induced by combined treatment with antiinflammatory drugs and enoxacin and its inhibition by a calcium antagonist, nicardipine. | Methods and findings in experimental and clinical pharmacology 19961101 |
| Intermolecular interactions of antimicrobial fluoroquinolones with purified rat liver CYP1A2 studied by proton nuclear magnetic resonance spectroscopy. | Xenobiotica; the fate of foreign compounds in biological systems 19961001 |
| Interaction between enoxacin, a new antimicrobial, and nimesulide, a new non-steroidal anti-inflammatory agent in mice. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 19960801 |
| Acute cholestatic liver injury induced by enoxacin. | Journal of hepatology 19930401 |
| [Effects of drugs on the convulsions induced by the combination of a new quinolone antimicrobial, enoxacin, and a nonsteroidal anti-inflammatory drug, fenbufen, in mice]. | Nihon yakurigaku zasshi. Folia pharmacologica Japonica 19921001 |
| Enoxacin acute liver injury. | Journal of hepatology 19920501 |
| Assessment of temafloxacin neurotoxicity in rodents. | The American journal of medicine 19911230 |
| Hippocampus and frontal cortex are the potential mediatory sites for convulsions induced by new quinolones and non-steroidal anti-inflammatory drugs. | International journal of clinical pharmacology, therapy, and toxicology 19910601 |
| Fluoroquinolones protect the human lymphocyte CEM cell line from HIV-1-mediated cytotoxicity. | Cell structure and function 19901001 |
| In vitro and in vivo antibacterial activities of AT-4140, a new broad-spectrum quinolone. | Antimicrobial agents and chemotherapy 19890801 |
| Comparative antimycobacterial activities of difloxacin, temafloxacin, enoxacin, pefloxacin, reference fluoroquinolones, and a new macrolide, clarithromycin. | Antimicrobial agents and chemotherapy 19890401 |
| Effect of enoxacin on theophylline neurotoxicity. | Life sciences 19890101 |
| Enoxacin in acute exacerbations of chronic bronchitis: a comparison with amoxycillin. | The Journal of antimicrobial chemotherapy 19880201 |
| Enoxacin in the treatment of lower respiratory tract infections. | The Journal of antimicrobial chemotherapy 19880201 |
| Activity of five fluoroquinolones against Mycobacterium avium-intracellulare complex and M. xenopi. | Annales de l'Institut Pasteur. Microbiology 19880101 |
| Comparative in-vitro activity of five fluoroquinolones against mycobacteria. | The Journal of antimicrobial chemotherapy 19870501 |
| In-vitro activity of six fluorinated quinolones against Mycobacterium tuberculosis. | The Journal of antimicrobial chemotherapy 19870501 |