Home Other Building Blocks Protoporphyrin ix disodium salt

Protoporphyrin ix disodium salt

CAS No.:
50865-01-5
Catalog Number:
AG003PRF
Molecular Formula:
C34H32N4Na2O4
Molecular Weight:
606.6218
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
250mg
90%
In Stock USA
United States
$72
- +
1g
90%
In Stock USA
United States
$244
- +
5g
90%
In Stock USA
United States
$863
- +
Product Description
Catalog Number:
AG003PRF
Chemical Name:
Protoporphyrin ix disodium salt
CAS Number:
50865-01-5
Molecular Formula:
C34H32N4Na2O4
Molecular Weight:
606.6218
MDL Number:
MFCD00151108
IUPAC Name:
disodium;3-[18-(2-carboxylatoethyl)-8,13-bis(ethenyl)-3,7,12,17-tetramethyl-22,23-dihydroporphyrin-2-yl]propanoate
InChI:
InChI=1S/C34H34N4O4.2Na/c1-7-21-17(3)25-13-26-19(5)23(9-11-33(39)40)31(37-26)16-32-24(10-12-34(41)42)20(6)28(38-32)15-30-22(8-2)18(4)27(36-30)14-29(21)35-25;;/h7-8,13-16,35-36H,1-2,9-12H2,3-6H3,(H,39,40)(H,41,42);;/q;2*+1/p-2
InChI Key:
GPRXGEKBQVXWAQ-UHFFFAOYSA-L
SMILES:
C=CC1=C(C)C2=N/C/1=C\c1[nH]c(c(c1C)C=C)/C=C/1\N=C(/C=c/3\[nH]/c(=C\2)/c(C)c3CCC(=O)[O-])C(=C1C)CCC(=O)[O-].[Na+].[Na+]
EC Number:
256-815-9
UNII:
54N4UY1C7C
Properties
Complexity:
995  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
3  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
606.222g/mol
Formal Charge:
0
Heavy Atom Count:
44  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
606.634g/mol
Monoisotopic Mass:
606.222g/mol
Rotatable Bond Count:
6  
Topological Polar Surface Area:
138A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Literature
Title Journal
Chronic Treatment with Isoniazid Causes Protoporphyrin IX Accumulation in Mouse Liver. Chemical research in toxicology 20160815
Involvement of Mouse Constitutive Androstane Receptor in Acifluorfen-Induced Liver Injury and Subsequent Tumor Development. Toxicological sciences : an official journal of the Society of Toxicology 20160601
Structural requirements within protoporphyrin IX in the inhibition of heat shock protein 90. Chemico-biological interactions 20130625
Reciprocal regulation of cyclooxygenase 2 and heme oxygenase 1 upon arsenic trioxide exposure in normal human lung fibroblast. Journal of biochemical and molecular toxicology 20130601
Aminolevulinic acid (ALA)-protoporphyrin IX fluorescence guided tumour resection. Part 2: theoretical, biochemical and practical aspects. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20121201
Interaction between holo transferrin and HSA-PPIX complex in the presence of lomefloxacin: an evaluation of PPIX aggregation in protein-protein interactions. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20121101
Aminolevulinic acid (ALA)-protoporphyrin IX fluorescence guided tumour resection. Part 1: Clinical, radiological and pathological studies. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20121101
Soluble diamagnetic model for malaria pigment: coordination chemistry of gallium(III)protoporphyrin-IX. Inorganic chemistry 20121015
On the autofluorescence of fingermarks. Forensic science international 20121010
Sodium butyrate increases the effect of the photodynamic therapy: a mechanism that involves modulation of gene expression and differentiation in astrocytoma cells. Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 20121001
Comparison of the uptake of 5-aminolevulinic acid and its methyl ester in keratinocytes and skin. Naunyn-Schmiedeberg's archives of pharmacology 20121001
Protoporphyrin IX formation and photobleaching in different layers of normal human skin: methyl- and hexylaminolevulinate and different light sources. Experimental dermatology 20121001
Polycyclic aromatic hydrocarbons (PAHs) mediate transcriptional activation of the ATP binding cassette transporter ABCB6 gene via the aryl hydrocarbon receptor (AhR). The Journal of biological chemistry 20120914
Differential cytotoxic response in keloid fibroblasts exposed to photodynamic therapy is dependent on photosensitiser precursor, fluence and location of fibroblasts within the lesion. Archives of dermatological research 20120901
Gadolinium- and 5-aminolevulinic acid-induced protoporphyrin IX levels in human gliomas: an ex vivo quantitative study to correlate protoporphyrin IX levels and blood-brain barrier breakdown. Journal of neuropathology and experimental neurology 20120901
[Fluorescence diagnosis of non-melanoma skin cancer]. Orvosi hetilap 20120826
Conserved chloroplast open-reading frame ycf54 is required for activity of the magnesium protoporphyrin monomethylester oxidative cyclase in Synechocystis PCC 6803. The Journal of biological chemistry 20120810
Effect of low temperature on chlorophyll biosynthesis in albinism line of wheat (Triticum aestivum) FA85. Physiologia plantarum 20120701
Phenytoin reduces 5-aminolevulinic acid-induced protoporphyrin IX accumulation in malignant glioma cells. Journal of neuro-oncology 20120701
Stem cell-based photodynamic therapy. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20120701
Validation of the protoporphyrin IX-triplet state lifetime technique for mitochondrial oxygen measurements in the skin. Optics letters 20120701
In vitro investigation of efficient photodynamic therapy using a nonviral vector; hemagglutinating virus of Japan envelope. Journal of biomedical optics 20120701
Multifunctional 5-aminolevulinic acid prodrugs activating diverse cell-death pathways. Investigational new drugs 20120601
Radiosensitizing effect of 5-aminolevulinic acid-induced protoporphyrin IX in glioma cells in vitro. Oncology reports 20120601
2-Aminopyrimidine based 4-aminoquinoline anti-plasmodial agents. Synthesis, biological activity, structure-activity relationship and mode of action studies. European journal of medicinal chemistry 20120601
The 18 kDa mitochondrial translocator protein (TSPO) prevents accumulation of protoporphyrin IX. Involvement of reactive oxygen species (ROS). Current molecular medicine 20120501
Pharmacological induction of heme oxygenase-1 by a triterpenoid protects neurons against ischemic injury. Stroke 20120501
Heme oxygenase-1 promotes the persistence of Leishmania chagasi infection. Journal of immunology (Baltimore, Md. : 1950) 20120501
Iron(III) protoporphyrin IX complexes of the antimalarial Cinchona alkaloids quinine and quinidine. ACS chemical biology 20120420
ATP-dependent mitochondrial porphyrin importer ABCB6 protects against phenylhydrazine toxicity. The Journal of biological chemistry 20120413
Apoptosis induced by sonodynamic treatment by protoporphyrin IX on MDA-MB-231 cells. Ultrasonics 20120401
PpIX fluorescence combined with auto-fluorescence is more accurate than PpIX fluorescence alone in fluorescence detection of non-melanoma skin cancer: an intra-patient direct comparison study. Lasers in surgery and medicine 20120401
5-Aminolevulinic acid-induced protoporphyrin IX fluorescence as immediate intraoperative indicator to improve the safety of malignant or high-grade brain tumor diagnosis in frameless stereotactic biopsies. Acta neurochirurgica 20120401
Porphyrin biodistribution in UV-exposed murine skin after methyl- and hexyl-aminolevulinate incubation. Experimental dermatology 20120401
¹¹C-methionine uptake and intraoperative 5-aminolevulinic acid-induced fluorescence as separate index markers of cell density in glioma: a stereotactic image-histological analysis. Cancer 20120315
Synthesis, radiometal labeling and in vitro evaluation of a targeted PPIX derivative. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20120301
Protoporphyrin IX-dependent photodynamic production of endogenous ROS stimulates cell proliferation. European journal of cell biology 20120301
Comparison of noninvasive photodynamic therapy dosimetry methods using a dynamic model of ALA-PDT of human skin. Physics in medicine and biology 20120207
C-terminal residues of oryza sativa GUN4 are required for the activation of the ChlH subunit of magnesium chelatase in chlorophyll synthesis. FEBS letters 20120203
Effect of surfactant on 5-aminolevulinic acid uptake and PpIX generation in human cholangiocarcinoma cell. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20120201
Protective effects of β-carotene and melanin against protoporphyrine IX-induced phototoxicity in the photo hen's egg test. Photodermatology, photoimmunology & photomedicine 20120201
[The role of tetrapyrrol photosensitizers in photoinduced variation of free radical characteristics of rat blood in endotoxic shock]. Biofizika 20120101
5-aminolevulinic acid-incorporated poly(vinyl alcohol) nanofiber-coated metal stent for application in photodynamic therapy. International journal of nanomedicine 20120101
[Soluble guanylate cyclase in the molecular mechanism underlying the therapeutic action of drugs]. Biomeditsinskaia khimiia 20120101
Poly(L-histidine)-tagged 5-aminolevulinic acid prodrugs: new photosensitizing precursors of protoporphyrin IX for photodynamic colon cancer therapy. International journal of nanomedicine 20120101
Low-intensity ultrasound combined with 5-aminolevulinic acid administration in the treatment of human tongue squamous carcinoma. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20120101
Serum-dependent export of protoporphyrin IX by ATP-binding cassette transporter G2 in T24 cells. Molecular and cellular biochemistry 20111201
δ-Aminolevulinic acid and its methyl ester induce the formation of Protoporphyrin IX in cultured sensory neurones. Naunyn-Schmiedeberg's archives of pharmacology 20111201
Addition of novel degenerate electrical waveform stimulation with photodynamic therapy significantly enhances its cytotoxic effect in keloid fibroblasts: first report of a potential combination therapy. Journal of dermatological science 20111201
Modulating ALA-PDT efficacy of mutlidrug resistant MCF-7 breast cancer cells using ALA prodrug. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20111201
Quantitative fluorescence imaging of protoporphyrin IX through determination of tissue optical properties in the spatial frequency domain. Journal of biomedical optics 20111201
Photosensitizer-loaded dendrimer-modified multi-walled carbon nanotubes for photodynamic therapy. Journal of controlled release : official journal of the Controlled Release Society 20111130
Aloe-emodin as antiproliferative and differentiating agent on human U937 monoblastic leukemia cells. Life sciences 20111121
Simultaneously targeting mitochondria and endoplasmic reticulum by photodynamic therapy induces apoptosis in human lymphoma cells. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20111101
Combined fluorescence and reflectance spectroscopy for in vivo quantification of cancer biomarkers in low- and high-grade glioma surgery. Journal of biomedical optics 20111101
Iron-coordinating tyrosine is a key determinant of NEAT domain heme transfer. Journal of molecular biology 20111028
5-Aminolevulinic acid-induced fluorescence diagnosis of pleural malignant tumor. Lung cancer (Amsterdam, Netherlands) 20111001
Protoporphyrin retention in hepatocytes and Kupffer cells prevents sclerosing cholangitis in erythropoietic protoporphyria mouse model. Gastroenterology 20111001
Oxygen-dependent delayed fluorescence measured in skin after topical application of 5-aminolevulinic acid. Journal of biophotonics 20111001
Carbon dots as antioxidants and prooxidants. Journal of biomedical nanotechnology 20111001
Retained topical delivery of 5-aminolevulinic acid using cationic ultradeformable liposomes for photodynamic therapy. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20110918
Isolation and characterization of squamous carcinoma cells resistant to photodynamic therapy. Journal of cellular biochemistry 20110901
Photodynamic therapy (PDT) - Initiation of apoptosis via activation of stress-activated p38 MAPK and JNK signal pathway in H460 cell lines. Photodiagnosis and photodynamic therapy 20110901
Photobleaching-based method to individualize irradiation time during interstitial 5-aminolevulinic acid photodynamic therapy. Photodiagnosis and photodynamic therapy 20110901
Protoporphyrin IX fluorescence contrast in invasive glioblastomas is linearly correlated with Gd enhanced magnetic resonance image contrast but has higher diagnostic accuracy. Journal of biomedical optics 20110901
Fluorescence detection and depletion of T47D breast cancer cells from human mononuclear cell-enriched blood preparations by photodynamic treatment: Basic in vitro experiments towards the removal of circulating tumor cells. Lasers in surgery and medicine 20110901
Intracutaneous ALA photodynamic therapy: dose-dependent targeting of skin structures. Lasers in surgery and medicine 20110901
Hexaminolevulinate-mediated photodynamic purging of marrow grafts with murine breast carcinoma. Bone marrow transplantation 20110801
The centrality of PBGD expression levels on ALA-PDT efficacy. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20110801
A protective protein matrix improves the discrimination of nitroxyl from nitric oxide by MnIII protoporphyrinate IX in aerobic media. Journal of inorganic biochemistry 20110801
Fluorescence illuminates the way .. Neuro-oncology 20110801
δ-aminolevulinic acid-induced protoporphyrin IX concentration correlates with histopathologic markers of malignancy in human gliomas: the need for quantitative fluorescence-guided resection to identify regions of increasing malignancy. Neuro-oncology 20110801
Photomicronucleus assay of phototoxic and pseudophotoclastogenic chemicals in human keratinocyte NCTC2544 cells. Mutation research 20110714
Neonatal bone marrow transplantation prevents liver disease in a murine model of erythropoietic protoporphyria. Journal of hepatology 20110701
Sonodynamically induced anti-tumor effect with protoporphyrin IX on hepatoma-22 solid tumor. Ultrasonics 20110701
Analysis of liquid crystalline nanoparticles by small angle X-ray diffraction: evaluation of drug and pharmaceutical additives influence on the internal structure. Journal of pharmaceutical sciences 20110701
Comparative study of the bactericidal effects of 5-aminolevulinic acid with blue and red light on Propionibacterium acnes. The Journal of dermatology 20110701
Measuring versus seeing. Journal of neurosurgery 20110701
Quantitative fluorescence in intracranial tumor: implications for ALA-induced PpIX as an intraoperative biomarker. Journal of neurosurgery 20110701
Targeting of sebaceous glands by δ-aminolevulinic acid-based photodynamic therapy: An in vivo study. Lasers in surgery and medicine 20110701
Comparative study of protoporphyrin IX fluorescence image enhancement methods to improve an optical imaging system for oral cancer detection. Journal of biomedical optics 20110701
Proton-coupled electron transfer reactions at a heme-propionate in an iron-protoporphyrin-IX model compound. Journal of the American Chemical Society 20110608
Simulation of fractionated and continuous irradiation in photodynamic therapy: study the differences between photobleaching and singlet oxygen dose deposition. Australasian physical & engineering sciences in medicine 20110601
An investigation of the fluorescence induced by topical application of 5-aminolaevulinic acid and methyl aminolaevulinate at different body sites on normal human skin. Photodiagnosis and photodynamic therapy 20110601
Comparison of protoporphyrin IX accumulation and destruction during methylaminolevulinate photodynamic therapy of skin tumours located at acral and nonacral sites. The British journal of dermatology 20110601
Targeted deletion of the mouse Mitoferrin1 gene: from anemia to protoporphyria. Blood 20110519
Inhibition of thioredoxin reductase 1 by porphyrins and other small molecules identified by a high-throughput screening assay. Free radical biology & medicine 20110501
Linear free energy relationships predict coordination and π-stacking interactions of small molecules with ferriprotoporphyrin IX. Journal of inorganic biochemistry 20110501
Drug delivery technologies and immunological aspects of photodynamic therapy. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20110501
Quantitative and qualitative 5-aminolevulinic acid-induced protoporphyrin IX fluorescence in skull base meningiomas. Neurosurgical focus 20110501
The effect of air cooling pain relief on protoporphyrin IX photobleaching and clinical efficacy during dermatological photodynamic therapy. Journal of photochemistry and photobiology. B, Biology 20110404
Biodistribution of PVP-hypericin and hexaminolevulinate-induced PpIX in normal and orthotopic tumor-bearing rat urinary bladder. Cancer chemotherapy and pharmacology 20110401
A novel proteomic approach reveals a role for Mg-protoporphyrin IX in response to oxidative stress. Physiologia plantarum 20110401
Monitoring of native fluorescence induced by a glucose diet in Wistar rats. Photomedicine and laser surgery 20110401
Monte Carlo modeling of in vivo protoporphyrin IX fluorescence and singlet oxygen production during photodynamic therapy for patients presenting with superficial basal cell carcinomas. Journal of biomedical optics 20110401
Coregistered fluorescence-enhanced tumor resection of malignant glioma: relationships between δ-aminolevulinic acid-induced protoporphyrin IX fluorescence, magnetic resonance imaging enhancement, and neuropathological parameters. Clinical article. Journal of neurosurgery 20110301
Silencing of ferrochelatase enhances 5-aminolevulinic acid-based fluorescence and photodynamic therapy efficacy. British journal of cancer 20110301
Enhancement of blood porphyrin emission intensity with aminolevulinic acid administration: a new concept for photodynamic diagnosis of early prostate cancer. Photodiagnosis and photodynamic therapy 20110301
Monitoring the accumulation and dissipation of the photosensitizer protoporphyrin IX during standard dermatological methyl-aminolevulinate photodynamic therapy utilizing non-invasive fluorescence imaging and quantification. Photodiagnosis and photodynamic therapy 20110301
[Nitric oxide donors activated by two-photon excitation]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20110301
Metal-substituted protein MRI contrast agents engineered for enhanced relaxivity and ligand sensitivity. Journal of the American Chemical Society 20110202
Quinolone compounds enhance delta-aminolevulinic acid-induced accumulation of protoporphyrin IX and photosensitivity of tumour cells. Journal of biochemistry 20110201
Hemin and magnesium-protoporphyrin IX induce global changes in gene expression in Chlamydomonas reinhardtii. Plant physiology 20110201
Epithelioid glioblastoma changed to typical glioblastoma: the methylation status of MGMT promoter and 5-ALA fluorescence. Brain tumor pathology 20110201
Precise comparison of protoporphyrin IX fluorescence spectra with pathological results for brain tumor tissue identification. Brain tumor pathology 20110201
Intense pulse light and 5-ALA PDT: phototoxic effects in vitro depend on the spectral overlap with protoporphyrine IX but do not match cut-off filter notations. Lasers in surgery and medicine 20110201
Detection and photodynamic therapy of inflamed atherosclerotic plaques in the carotid artery of rabbits. Journal of photochemistry and photobiology. B, Biology 20110110
Evaluation of photodynamic therapy (PDT) procedures using microfluidic system. Analytica chimica acta 20110110
Targeting of p53 and its homolog p73 by protoporphyrin IX. FEBS letters 20110103
Effect and mechanism of 5-aminolevulinic acid-mediated photodynamic therapy in esophageal cancer. Lasers in medical science 20110101
Symbiotic association between soybean plants and Bradyrhizobium japonicum develops oxidative stress and heme oxygenase-1 induction at early stages. Redox report : communications in free radical research 20110101
Effect of 5-aminolevulinic acid-based photodynamic therapy via reactive oxygen species in human cholangiocarcinoma cells. International journal of nanomedicine 20110101
An in vitro comparison of the effects of the iron-chelating agents, CP94 and dexrazoxane, on protoporphyrin IX accumulation for photodynamic therapy and/or fluorescence guided resection. Photochemistry and photobiology 20110101
Utility of intraoperative fluorescent diagnosis of residual hemangioblastoma using 5-aminolevulinic acid. Neurology India 20110101
Fluorescence photobleaching of ALA and ALA-heptyl ester induced protoporphyrin IX during photodynamic therapy of normal hairless mouse skin: a comparison of two light sources and different illumination schemes. Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20110101
Identification and characterization of an inhibitory metal ion-binding site in ferrochelatase. The Journal of biological chemistry 20101231
The role of nitric oxide in the treatment of tumours with aminolaevulinic acid-induced photodynamic therapy. Journal of photochemistry and photobiology. B, Biology 20101202
Identification of specific inhibitors for a trypanosomatid RNA editing reaction. RNA (New York, N.Y.) 20101201
Two-photon irradiation of an intracellular singlet oxygen photosensitizer: achieving localized sub-cellular excitation in spatially-resolved experiments. Free radical research 20101201
Protoporphyrin IX photobleaching during the light irradiation phase of standard dermatological methyl-aminolevulinate photodynamic therapy. Photodiagnosis and photodynamic therapy 20101201
Determination of time-dependent protoporphyrin IX concentration for photodynamic therapy dosimetry in a mice colon tumor model using fluorescence spectroscopy. Applied spectroscopy 20101201
Intrinsic fluorescence of protoporphyrin IX from blood samples can yield information on the growth of prostate tumours. Journal of fluorescence 20101101
Tetrapyrrole binding affinity of the murine and human p22HBP heme-binding proteins. Journal of molecular graphics & modelling 20101101
The efficacy of photodynamic diagnosis in defining the lateral border between a tumor and a tumor-free area during Mohs micrographic surgery. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20101101
BchJ and BchM interact in a 1 : 1 ratio with the magnesium chelatase BchH subunit of Rhodobacter capsulatus. The FEBS journal 20101101
ABCG2 transports and transfers heme to albumin through its large extracellular loop. The Journal of biological chemistry 20101022
Hexaminolevulinate-mediated photodynamic purging of leukemia cells from BM. Bone marrow transplantation 20101001
Microneedle pre-treatment of human skin improves 5-aminolevulininc acid (ALA)- and 5-aminolevulinic acid methyl ester (MAL)-induced PpIX production for topical photodynamic therapy without increase in pain or erythema. Pharmaceutical research 20101001
Kinetics and specificity of feline leukemia virus subgroup C receptor (FLVCR) export function and its dependence on hemopexin. The Journal of biological chemistry 20100910
Anticancer effect of photodynamic therapy with hexenyl ester of 5-aminolevulinic acid in oral squamous cell carcinoma. Head & neck 20100901
Penetration enhancement of two topical 5-aminolaevulinic acid formulations for photodynamic therapy by erbium:YAG laser ablation of the stratum corneum: continuous versus fractional ablation. Experimental dermatology 20100901
Reduction of cutaneous photosensitivity by application of ointment containing ferrous or cobaltous ions concomitant with the use of topical protoporphyrin IX precursors. Photodiagnosis and photodynamic therapy 20100901
In vivo temporal evolution of ALA-induced normalized fluorescence at different anatomical locations of oral cavity: application to improve cancer diagnostic contrast and potential. Photodiagnosis and photodynamic therapy 20100901
Antitumor properties of aloe-emodin and induction of transglutaminase 2 activity in B16-F10 melanoma cells. Life sciences 20100828
Fluorescence induction of protoporphyrin IX by a new 5-aminolevulinic acid nanoemulsion used for photodynamic therapy in a full-thickness ex vivo skin model. Experimental dermatology 20100801
In vivo binding of protoporphyrin IX to rat translocator protein imaged with positron emission tomography. Synapse (New York, N.Y.) 20100801
Uptake and kinetics of 5-aminolevulinic acid in oral squamous cell carcinoma. International journal of oral and maxillofacial surgery 20100801
Factors influencing pain intensity during topical photodynamic therapy of complete cosmetic units for actinic keratoses. Journal of the American Academy of Dermatology 20100801
Comparison of pharmacokinetics, intracellular localizations and sonodynamic efficacy of endogenous and exogenous protoporphyrin IX in sarcoma 180 cells. Ultrasonics 20100801
Improving intraoperative visualization of anaplastic foci within gliomas. Neurosurgery 20100801
Fractional laser as a tool to enhance the skin permeation of 5-aminolevulinic acid with minimal skin disruption: a comparison with conventional erbium:YAG laser. Journal of controlled release : official journal of the Controlled Release Society 20100714
The effects of keratolytic pretreatment prior to fluorescence diagnosis and photodynamic therapy with aminolevulinic acid-induced porphyrins in psoriasis. The Journal of dermatological treatment 20100701
Photodynamic therapy with intradermal administration of 5-aminolevulinic acid for port-wine stains. The Journal of dermatological treatment 20100701
Nitric oxide blocks cellular heme insertion into a broad range of heme proteins. Free radical biology & medicine 20100601
Validation of a non-invasive fluorescence imaging system to monitor dermatological PDT. Photodiagnosis and photodynamic therapy 20100601
Demonstration of protoporphyrin IX (PpIX) localized to areas of palmar skin injected with 5-aminolevulinic acid (ALA) and pre-treated with a fractionated CO2 laser prior to topically applied ALA. Photodiagnosis and photodynamic therapy 20100601
Reduction of arsenic-induced cytotoxicity through Nrf2/HO-1 signaling in HepG2 cells. The Journal of toxicological sciences 20100601
In vivo production of catalase containing haem analogues. The FEBS journal 20100601
A case of Bowen's disease successfully treated by photodynamic therapy. Journal of Nippon Medical School = Nippon Ika Daigaku zasshi 20100601
Study of blood porphyrin spectral profile for diagnosis of chronic renal failure. Journal of fluorescence 20100501
Folic acid-conjugated chitosan nanoparticles enhanced protoporphyrin IX accumulation in colorectal cancer cells. Bioconjugate chemistry 20100421
Gender dimorphic formation of mouse Mallory-Denk bodies and the role of xenobiotic metabolism and oxidative stress. Gastroenterology 20100401
Sonodynamically induced apoptosis by protoporphyrin IX on hepatoma-22 cells in vitro. Ultrasound in medicine & biology 20100401
The influence of temperature on 5-aminolevulinic acid-based photodynamic reaction in keratinocytes in vitro. Photodermatology, photoimmunology & photomedicine 20100401
Two coregulated efflux transporters modulate intracellular heme and protoporphyrin IX availability in Streptococcus agalactiae. PLoS pathogens 20100401
Desferrioxamine shows different potentials for enhancing 5-aminolaevulinic acid-based photodynamic therapy in several cutaneous cell lines. Lasers in medical science 20100301
Photodynamic antimicrobial activity of avian eggshell pigments. FEBS letters 20100219
Boron-containing protoporphyrin IX derivatives and their modification for boron neutron capture therapy: synthesis, characterization, and comparative in vitro toxicity evaluation. Chemistry (Weinheim an der Bergstrasse, Germany) 20100201
Nitric oxide sensitive guanylyl cyclase activity decreases during cerebral postnatal development because of a reduction in heterodimerization. Journal of neurochemistry 20100101
Intralesional photodynamic therapy: a comment on 'Pretreatment to enhance protoporphyrin IX accumulation in photodynamic therapy' by Gerritsen et al. Dermatology (Basel, Switzerland) 20100101
Deferoxamine iron chelation increases delta-aminolevulinic acid induced protoporphyrin IX in xenograft glioma model. Photochemistry and photobiology 20100101
Preferential accumulation of 5-aminolevulinic acid-induced protoporphyrin IX in breast cancer: a comprehensive study on six breast cell lines with varying phenotypes. Journal of biomedical optics 20100101
Apoptosis-accommodating effect of nitric oxide in photodynamically stressed tumor cells. Photochemistry and photobiology 20100101
Metronomic PDT and cell death pathways. Methods in molecular biology (Clifton, N.J.) 20100101
Application of 5-aminolevulinic acid and its derivatives for photodynamic therapy in vitro and in vivo. Methods in molecular biology (Clifton, N.J.) 20100101
Fractionated illumination at low fluence rate photodynamic therapy in mice. Photochemistry and photobiology 20100101
The hydroxypyridinone iron chelator CP94 can enhance PpIX-induced PDT of cultured human glioma cells. Photochemistry and photobiology 20100101
5-Aminolevulinic acid-induced protoporphyrin IX levels in tissue of human malignant brain tumors. Photochemistry and photobiology 20100101
Noninvasive fluorescence monitoring of protoporphyrin IX production and clinical outcomes in actinic keratoses following short-contact application of 5-aminolevulinate. Journal of biomedical optics 20100101
Spectroscopic and biological studies of a novel synthetic chlorin derivative with prospects for use in PDT. Bioorganic & medicinal chemistry 20091215
5-ALA derivative-mediated photoinactivation of Propionibacterium acnes. Journal of dermatological science 20091201
Enlightened protein: Fhit tumor suppressor protein structure and function and its role in the toxicity of protoporphyrin IX-mediated photodynamic reaction. Toxicology and applied pharmacology 20091201
Mechanism of cell death by 5-aminolevulinic acid-based photodynamic action and its enhancement by ferrochelatase inhibitors in human histiocytic lymphoma cell line U937. Cell biochemistry and function 20091201
Heating increases protoporphyrin IX production in normal skin after delivery of 5-aminolevulinic acid by iontophoresis. Photodermatology, photoimmunology & photomedicine 20091201
A comparative study on the enhancement efficacy of specific and non-specific iron chelators for protoporphyrin IX production and photosensitization in HaCat cells. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20091201
Precise detection of lymph node metastases in mouse rectal cancer by using 5-aminolevulinic acid. International journal of cancer 20091115
An enzyme-coupled continuous spectrophotometric assay for magnesium protoporphyrin IX methyltransferases. Analytical biochemistry 20091115
Treatment of perianal Paget's disease using photodynamic therapy with assistance of fluorescence examination: case report. Lasers in medical science 20091101
A comparison of 5-aminolaevulinic acid- and its heptyl ester: dark cytotoxicity and protoporphyrin IX synthesis in human adenocarcinoma WiDr cells and in athymic nude mice healthy skin. Experimental dermatology 20091101
Topical delivery of 5-aminolevulinic acid-encapsulated ethosomes in a hyperproliferative skin animal model using the CLSM technique to evaluate the penetration behavior. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20091101
Topical aminolaevulinic acid- and aminolaevulinic acid methyl ester-based photodynamic therapy with red and violet light: influence of wavelength on pain and erythema. The British journal of dermatology 20091101
Simulations of measured photobleaching kinetics in human basal cell carcinomas suggest blood flow reductions during ALA-PDT. Lasers in surgery and medicine 20091101
Photodynamic therapy with 5-aminolevulinic acid and diamino acid derivatives of protoporphyrin IX reduces papillomas in mice without eliminating transformation into squamous cell carcinoma of the skin. International journal of cancer 20091001
Photochemically induced increase in endothelial permeability regulated by RhoA activation. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20091001
Silencing of ALA dehydratase affects ALA-photodynamic therapy efficacy in K562 erythroleukemic cells. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20091001
Synergistic increase in osteosarcoma cell sensitivity to photodynamic therapy with aminolevulinic acid hexyl ester in the presence of hyperthermia. Photomedicine and laser surgery 20091001
Signaling events in apoptotic photokilling of 5-aminolevulinic acid-treated tumor cells: inhibitory effects of nitric oxide. Free radical biology & medicine 20090915
Porphyrins promote the association of GENOMES UNCOUPLED 4 and a Mg-chelatase subunit with chloroplast membranes. The Journal of biological chemistry 20090911
New aspects in photodynamic therapy of actinic keratoses. Journal of photochemistry and photobiology. B, Biology 20090904
Porphyrin synthesis from aminolevulinic acid esters in endothelial cells and its role in photodynamic therapy. Journal of photochemistry and photobiology. B, Biology 20090904
Site-directed mutagenesis and computational study of the Y366 active site in Bacillus subtilis protoporphyrinogen oxidase. Amino acids 20090901
The interplay between iron and zinc metabolism in Aspergillus fumigatus. Fungal genetics and biology : FG & B 20090901
Parallel pigment and transcriptomic analysis of four barley albina and xantha mutants reveals the complex network of the chloroplast-dependent metabolism. Plant molecular biology 20090901
Calcitriol treatment improves methyl aminolaevulinate-based photodynamic therapy in human squamous cell carcinoma A431 cells. The British journal of dermatology 20090801
A time course investigation of the fluorescence induced by topical application of 5-aminolevulinic acid and methyl aminolevulinate on normal human skin. Photodermatology, photoimmunology & photomedicine 20090801
Aberration of the enzymatic activity of Fhit tumor suppressor protein enhances cancer cell death upon photodynamic therapy similarly to that driven by wild-type Fhit. Cancer letters 20090718
Improved peptide prodrugs of 5-ALA for PDT: rationalization of cellular accumulation and protoporphyrin IX production by direct determination of cellular prodrug uptake and prodrug metabolization. Journal of medicinal chemistry 20090709
Analysis of chlorophylls and their derivatives by matrix-assisted laser desorption/ionization-time-of-flight mass spectrometry. Analytical biochemistry 20090701
[Intraoperative photo-dynamic diagnosis of brain tumors]. Brain and nerve = Shinkei kenkyu no shinpo 20090701
Ros production by endogenously generated Protoporphyrin IX in murine leukemia cells. Cellular and molecular biology (Noisy-le-Grand, France) 20090701
Surgical outcomes of fluorescence-guided laparoscopic partial nephrectomy using 5-aminolevulinic acid-induced protoporphyrin IX. The Journal of surgical research 20090615
Mitochondrial oxygen tension within the heart. Journal of molecular and cellular cardiology 20090601
Low-dose methotrexate enhances aminolevulinate-based photodynamic therapy in skin carcinoma cells in vitro and in vivo. Clinical cancer research : an official journal of the American Association for Cancer Research 20090515
Sustained and efficient porphyrin generation in vivo using dendrimer conjugates of 5-ALA for photodynamic therapy. Journal of controlled release : official journal of the Controlled Release Society 20090417
Etretinate enhances the susceptibility of human skin squamous cell carcinoma cells to 5-aminolaevulic acid-based photodynamic therapy. Clinical and experimental dermatology 20090401
Induction of protoporphyrin IX by aminolaevulinic acid in actinic keratosis, psoriasis and normal skin: preferential porphyrin enrichment in differentiated cells. The British journal of dermatology 20090401
Protoporphyrin IX enhancement by 5-aminolaevulinic acid peptide derivatives and the effect of RNA silencing on intracellular metabolism. British journal of cancer 20090310
Influence of formulation factors on PpIX production and photodynamic action of novel ALA-loaded microparticles. Biopharmaceutics & drug disposition 20090301
Hypericin and 5-aminolevulinic acid-induced protoporphyrin IX induce enhanced phototoxicity in human endometrial cancer cells with non-coherent white light. Photodiagnosis and photodynamic therapy 20090301
Interactions of protoporphyrin IX and its derivatives with benzodiazepine receptor. Photodiagnosis and photodynamic therapy 20090301
Interactions of peripheral-type benzodiazepine receptor with diamino acid derivatives of protoporphyrin IX. Journal of photochemistry and photobiology. B, Biology 20090209
Influence of protoporphyrin IX amino acid substituents on affinity to human breast adenocarcinoma MCF-7 cells. Biotechnic & histochemistry : official publication of the Biological Stain Commission 20090201
Damage effects of protoporphyrin IX - sonodynamic therapy on the cytoskeletal F-actin of Ehrlich ascites carcinoma cells. Ultrasonics sonochemistry 20090101
Heme oxygenase is necessary for the excitatory response of cultured neonatal rat rostral ventrolateral medulla neurons to hypoxia. American journal of physiology. Regulatory, integrative and comparative physiology 20090101
Pretreatment to enhance protoporphyrin IX accumulation in photodynamic therapy. Dermatology (Basel, Switzerland) 20090101
Skin and mucosal fluorescence diagnosis with different light sources. European journal of dermatology : EJD 20090101
Depth profile of protoporphyrin IX fluorescence in an amelanotic mouse melanoma model. Photochemistry and photobiology 20090101
Noninvasive measurement of aminolevulinic acid-induced protoporphyrin IX fluorescence allowing detection of murine glioma in vivo. Journal of biomedical optics 20090101
Imaging of glioma tumor with endogenous fluorescence tomography. Journal of biomedical optics 20090101
Improved diagnosis of oral premalignant lesions in submucous fibrosis patients with 5-aminolevulinic acid induced PpIX fluorescence. Journal of biomedical optics 20090101
Heme mediates cytotoxicity from artemisinin and serves as a general anti-proliferation target. PloS one 20090101
Regulation of heme synthesis and proteasomal activity by copper: possible implications for Wilson's disease. Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20090101
A preliminary study of protoporphyrin-IX as a potential candidate for identification of lung cancer cells using fluorescence microscopy. Photodiagnosis and photodynamic therapy 20090101
Regulation of 5-aminolevulinic acid-mediated protoporphyrin IX accumulation in human urothelial carcinomas. Pathobiology : journal of immunopathology, molecular and cellular biology 20090101
[Fluorescence diagnostics of skin tumors using 5-aminolevulinic acid and its methyl ester]. Medicina (Kaunas, Lithuania) 20090101
Ligand binding to the Fe(III)-protoporphyrin IX complex of phosphodiesterase from Escherichia coli (Ec DOS) markedly enhances catalysis of cyclic di-GMP: roles of Met95, Arg97, and Phe113 of the putative heme distal side in catalytic regulation and ligand binding. Biochemistry 20081216
Comparison of ALA- and ALA hexyl-ester-induced PpIX depth distribution in human skin carcinoma. Journal of photochemistry and photobiology. B, Biology 20081211
The IsdC protein from Staphylococcus aureus uses a flexible binding pocket to capture heme. The Journal of biological chemistry 20081114
Protoporphyrin IX nanoparticle carrier: preparation, optical properties, and singlet oxygen generation. Langmuir : the ACS journal of surfaces and colloids 20081104
Melatonin and environmental lighting regulate ALA-S gene expression and So porphyrin biosynthesis in the rat harderian gland. Chronobiology international 20081101
[Detection of singlet oxygen and superoxide anion with the fluorescence of FCLA]. Guang pu xue yu guang pu fen xi = Guang pu 20081101
[Two-photon excitation fluorescence of 5-ALA induced PpIX in DHL cells]. Guang pu xue yu guang pu fen xi = Guang pu 20081101
In vivo mitochondrial oxygen tension measured by a delayed fluorescence lifetime technique. Biophysical journal 20081015
Sufficient PpIX production for PDT even with short contact time of topically applied 5-ALA in rabbit tongues. Lasers in medical science 20081001
A HCl/alcohol formulation increased 5-aminolevulinic acid skin distribution using an ex vivo full thickness porcine skin model. Experimental dermatology 20081001
Selective accumulation of PpIX and photodynamic effect after aminolevulinic acid treatment of human adenomyosis xenografts in nude mice. Fertility and sterility 20081001
Analysis of differential PDT effect in rat bladder tumor models according to concentrations of intravesical hexyl-aminolevulinate. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20080901
Effect of (R)L-sulforaphane on 5-aminolevulinic acid-mediated photodynamic therapy. Translational research : the journal of laboratory and clinical medicine 20080901
Effects of PDT with 5-aminolevulinic acid and chitosan on Walker carcinosarcoma. Experimental oncology 20080901
Metal ion substrate inhibition of ferrochelatase. The Journal of biological chemistry 20080829
Microscopic localisation of protoporphyrin IX in normal mouse skin after topical application of 5-aminolevulinic acid or methyl 5-aminolevulinate. Journal of photochemistry and photobiology. B, Biology 20080821
Enhancement of methyl-aminolevulinate photodynamic therapy by iron chelation with CP94: an in vitro investigation and clinical dose-escalating safety study for the treatment of nodular basal cell carcinoma. Journal of cancer research and clinical oncology 20080801
Deletion of caveolin-1 protects against oxidative lung injury via up-regulation of heme oxygenase-1. American journal of respiratory cell and molecular biology 20080801
[Identification of protoporphyrin IX fluorescence spectrum in human blood serum by biorthogonal spline wavelet]. Guang pu xue yu guang pu fen xi = Guang pu 20080801
Irradiance-dependent photobleaching and pain in delta-aminolevulinic acid-photodynamic therapy of superficial basal cell carcinomas. Clinical cancer research : an official journal of the American Association for Cancer Research 20080715
Relationship of protoporphyrin IX synthesis to photodynamic effects by 5-aminolaevulinic acid and its esters on various cell lines derived from the skin. The British journal of dermatology 20080701
Protoporphyrin IX fluorescence photobleaching is a useful tool to predict the response of rat ovarian cancer following hexaminolevulinate photodynamic therapy. Lasers in surgery and medicine 20080701
Stimulation and inhibition of 5 ALA induced PplX fluorescence in the diagnosis of fibrosarcoma cultivated on the CAM using glucose versus ethanol as modulating agents. The Gulf journal of oncology 20080701
5-Aminolaevulinic acid peptide prodrugs enhance photosensitization for photodynamic therapy. Molecular cancer therapeutics 20080601
Comparison of 5-aminolevulinic acid-encapsulated liposome versus ethosome for skin delivery for photodynamic therapy. International journal of pharmaceutics 20080522
Role of PUG1 in inducible porphyrin and heme transport in Saccharomyces cerevisiae. Eukaryotic cell 20080501
Substrate-binding model of the chlorophyll biosynthetic magnesium chelatase BchH subunit. The Journal of biological chemistry 20080425
Continuous activation of PpIX by daylight is as effective as and less painful than conventional photodynamic therapy for actinic keratoses; a randomized, controlled, single-blinded study. The British journal of dermatology 20080401
Glycoside esters of 5-aminolevulinic acid for photodynamic therapy of cancer. Bioconjugate chemistry 20080401
Kinetics and subcellular localization of 5-ALA-induced PpIX in DHL cells via two-photon excitation fluorescence microscopy. International journal of oncology 20080401
Enhancement of apoptosis by sonodynamic therapy with protoporphyrin IX in isolate sarcoma 180 cells. Cancer biotherapy & radiopharmaceuticals 20080401
Resonance energy transfer and ligand binding studies on pH-induced folded states of human serum albumin. Journal of photochemistry and photobiology. B, Biology 20080328
5-aminolevulinic acid induced protoporphyrin IX fluorescence in high-grade glioma surgery: a one-year experience at a single institutuion. Swiss medical weekly 20080322
Inhibition of glutathione-S-transferase from Plasmodium yoelii by protoporphyrin IX, cibacron blue and menadione: implications and therapeutic benefits. Parasitology research 20080301
Long-pulsed dye laser versus long-pulsed dye laser-assisted photodynamic therapy for acne vulgaris: A randomized controlled trial. Journal of the American Academy of Dermatology 20080301
Heme, a plastid-derived regulator of nuclear gene expression in Chlamydomonas. The Plant cell 20080301
ALA and its clinical impact, from bench to bedside. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20080301
In vivo and in vitro characterisation of a protoporphyrin IX-cyclic RGD peptide conjugate for use in photodynamic therapy. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20080301
Apolipoprotein B binds ferritin by hemin-mediated binding: evidence of direct binding of apolipoprotein B and ferritin to hemin. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20080201
Silencing of human ferrochelatase causes abundant protoporphyrin-IX accumulation in colon cancer. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20080201
Fluorescence characteristics and pharmacokinetic properties of a novel self-adhesive 5-ALA patch for photodynamic therapy of actinic keratoses. Archives of dermatological research 20080201
Auditory alert system for fluorescence-guided resection of gliomas. Neurologia medico-chirurgica 20080201
Fluorescence kinetics of protoporphyrin-IX induced from 5-ALA compounds in rabbit postballoon injury model for ALA-photoangioplasty. Photochemistry and photobiology 20080101
The photosensitizing potential of compact fluorescent vs incandescent light bulbs. Photochemistry and photobiology 20080101
Monitoring ALA-induced PpIX photodynamic therapy in the rat esophagus using fluorescence and reflectance spectroscopy. Photochemistry and photobiology 20080101
Heme oxygenase-1 attenuates contact hypersensitivity induced by 2,4-dinitrofluorobenzene in mice. Immunopharmacology and immunotoxicology 20080101
[Fluorescent diagnostic methods and superficial cancer of the urinary bladder: current status]. Urologiia (Moscow, Russia : 1999) 20080101
Adenine nucleotide translocator transports haem precursors into mitochondria. PloS one 20080101
Nrf2-dependent induction of human ABC transporter ABCG2 and heme oxygenase-1 in HepG2 cells by photoactivation of porphyrins: biochemical implications for cancer cell response to photodynamic therapy. Journal of experimental therapeutics & oncology 20080101
[Photodamage to spores of Fusarium fungi, sensitized by protoporphyrin IX]. Biofizika 20080101
Microscopic distribution of protoporphyrin (PpIX) fluorescence in superficial basal cell carcinoma during light-fractionated aminolaevulinic acid photodynamic therapy. Acta dermato-venereologica 20080101
Porphyrin homeostasis maintained by ABCG2 regulates self-renewal of embryonic stem cells. PloS one 20080101
Characterization of temperature-dependent iron-imidazole vibrational modes in far infrared. The journal of physical chemistry. B 20071227
Sensitivity of osteoblasts, fibroblasts, bone marrow cells, and dendritic cells to 5-aminolevulinic acid based photodynamic therapy. Journal of photochemistry and photobiology. B, Biology 20071214
Inhibition of heme oxygenase-1 increases responsiveness of melanoma cells to ALA-based photodynamic therapy. International journal of oncology 20071201
Analyzing effects of photodynamic therapy with 5-aminolevulinic acid (ALA) induced protoporphyrin IX (PPIX) in urothelial cells using reverse phase protein arrays. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20071201
Erythroblasts highly express the ABC transporter Bcrp1/ABCG2 but do not show the side population (SP) phenotype. Immunology letters 20071130
Fluorescence diagnosis in keratinocytic intraepidermal neoplasias. Journal of the American Academy of Dermatology 20071101
['... The better to see you with'--phothodynamic diagnostic in superficial bladder cancer]. Praxis 20071017
Carbon monoxide produced by heme oxygenase-1 in response to nitrosative stress induces expression of glutamate-cysteine ligase in PC12 cells via activation of phosphatidylinositol 3-kinase and Nrf2 signaling. The Journal of biological chemistry 20070928
5-Aminolevulinic acid-induced protoporphyrin-IX accumulation and associated phototoxicity in macrophages and oral cancer cell lines. Journal of photochemistry and photobiology. B, Biology 20070925
Interaction of heme and heme-hemopexin with an extracellular oxidant system used to measure cell growth-associated plasma membrane electron transport. Biochimica et biophysica acta 20070901
A mitochondrial protein homologous to the mammalian peripheral-type benzodiazepine receptor is essential for stress adaptation in plants. The Plant journal : for cell and molecular biology 20070901
Increased expression of mitochondrial benzodiazepine receptors following low-level light treatment facilitates enhanced protoporphyrin IX production in glioma-derived cells in vitro. Lasers in surgery and medicine 20070901
Detection of heme oxygenase activity in a library of four-helix bundle proteins: towards the de novo synthesis of functional heme proteins. Journal of molecular biology 20070817
Novel prodrug approach to photodynamic therapy: Fmoc solid-phase synthesis of a cell permeable peptide incorporating 5-aminolaevulinic acid. Bioorganic & medicinal chemistry letters 20070815
Cloning and characterization of a novel periplasmic heme-transport protein from the human pathogen Pseudomonas aeruginosa. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20070801
Parasiticidal effect of delta-aminolevulinic acid-based photodynamic therapy for cutaneous leishmaniasis is indirect and mediated through the killing of the host cells. Experimental dermatology 20070801
Increase in protoporphyrin IX after 5-aminolevulinic acid based photodynamic therapy is due to local re-synthesis. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20070801
Comparison of aminolevulinic acid- and hexylester aminolevulinate-induced protoporphyrin IX fluorescence for the detection of ovarian cancer in a rat model. Photomedicine and laser surgery 20070801
In vivo quantification of fluorescent molecular markers in real-time by ratio imaging for diagnostic screening and image-guided surgery. Lasers in surgery and medicine 20070801
The CHLI1 subunit of Arabidopsis thaliana magnesium chelatase is a target protein of the chloroplast thioredoxin. The Journal of biological chemistry 20070706
The peripheral-type benzodiazepine receptor is involved in control of Ca2+-induced permeability transition pore opening in rat brain mitochondria. Cell calcium 20070701
Massive apoptotic cell death of human glioma cells via a mitochondrial pathway following 5-aminolevulinic acid-mediated photodynamic therapy. Journal of neuro-oncology 20070701
Photodetection of basal cell carcinoma using methyl 5-aminolaevulinate-induced protoporphyrin IX based on fluorescence image analysis. Clinical and experimental dermatology 20070701
Two-photon photodynamic therapy of C6 cells by means of 5-aminolevulinic acid induced protoporphyrin IX. Journal of photochemistry and photobiology. B, Biology 20070626
A new dinuclear heme-copper complex derived from functionalized protoporphyrin IX. Dalton transactions (Cambridge, England : 2003) 20070607
Expression and simple, one-step purification of fragile histidine triad (Fhit) tumor suppressor mutant forms in Escherichia coli and their interaction with protoporphyrin IX. Biotechnology letters 20070601
Impairment of the photosynthetic apparatus by oxidative stress induced by photosensitization reaction of protoporphyrin IX. Biochimica et biophysica acta 20070601
Interstitial photodynamic therapy of nonresectable malignant glioma recurrences using 5-aminolevulinic acid induced protoporphyrin IX. Lasers in surgery and medicine 20070601
In vivo visualization of Mg-protoporphyrin IX, a coordinator of photosynthetic gene expression in the nucleus and the chloroplast. The Plant cell 20070601
Expression of genes involved in heme biosynthesis in the human retinoblastoma cell lines WERI-Rb-1 and Y79: implications for photodynamic therapy. Journal of experimental & clinical cancer research : CR 20070601
Biological activity of 5-aminolevulinic acid and its methyl ester after storage under different conditions. Journal of photochemistry and photobiology. B, Biology 20070525
Signals from chloroplasts converge to regulate nuclear gene expression. Science (New York, N.Y.) 20070504
Plant science. Signaling to the nucleus with a loaded GUN. Science (New York, N.Y.) 20070504
A reporter system for the individual detection of hydrogen peroxide and singlet oxygen: its use for the assay of reactive oxygen species produced in vivo. The Plant journal : for cell and molecular biology 20070501
Vitamin D enhances ALA-induced protoporphyrin IX production and photodynamic cell death in 3-D organotypic cultures of keratinocytes. The Journal of investigative dermatology 20070401
Limitation of nocturnal import of ATP into Arabidopsis chloroplasts leads to photooxidative damage. The Plant journal : for cell and molecular biology 20070401
Statins attenuate ischemia-reperfusion injury by inducing heme oxygenase-1 in infiltrating macrophages. The American journal of pathology 20070401
Detection of urinary bladder cancer with flow cytometry and hexaminolevulinate in urine samples. Cytopathology : official journal of the British Society for Clinical Cytology 20070401
Study of the efficacy and mechanism of ALA-mediated photodynamic therapy on human hepatocellular carcinoma cell. Liver international : official journal of the International Association for the Study of the Liver 20070301
Endoscopic identification and biopsy sampling of an intraventricular malignant glioma using a 5-aminolevulinic acid-induced protoporphyrin IX fluorescence imaging system. Technical note. Journal of neurosurgery 20070301
The role of nitric oxide in delta-aminolevulinic acid (ALA)-induced photosensitivity of cancerous cells. Biochemical and biophysical research communications 20070216
Relation between intracellular location and photodynamic efficacy of 5-aminolevulinic acid-induced protoporphyrin IX in vitro. Comparison between human glioblastoma cells and other cancer cell lines. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20070201
Quantitative spectroscopic analysis of 5-aminolevulinic acid-induced protoporphyrin IX fluorescence intensity in diffusely infiltrating astrocytomas. Neurologia medico-chirurgica 20070201
Protoporphyrin IX interacts with wild-type p53 protein in vitro and induces cell death of human colon cancer cells in a p53-dependent and -independent manner. The Journal of biological chemistry 20070126
Amino acid residues His183 and Glu264 in Bacillus subtilis ferrochelatase direct and facilitate the insertion of metal ion into protoporphyrin IX. Biochemistry 20070109
Tumor suppressor Fhit protein interacts with protoporphyrin IX in vitro and enhances the response of HeLa cells to photodynamic therapy. Journal of photochemistry and photobiology. B, Biology 20070103
Hexyl-aminolevulinate-mediated photodynamic therapy: how to spare normal urothelium. An in vitro approach. Lasers in surgery and medicine 20070101
Proteins of insoluble matrix of avian (gallus gallus) eggshell. Connective tissue research 20070101
DNA-directed immobilization of horseradish peroxidase-DNA conjugates on microelectrode arrays: towards electrochemical screening of enzyme libraries. Chemistry (Weinheim an der Bergstrasse, Germany) 20070101
In-vivo kinetics of inhaled 5-aminolevulinic acid-induced protoporphyrin IX fluorescence in bronchial tissue. Respiratory research 20070101
Photobleaching-based dosimetry predicts deposited dose in ALA-PpIX PDT of rodent esophagus. Photochemistry and photobiology 20070101
Direct comparison of delta-aminolevulinic acid and methyl-aminolevulinate-derived protoporphyrin IX accumulations potentiated by desferrioxamine or the novel hydroxypyridinone iron chelator CP94 in cultured human cells. Photochemistry and photobiology 20070101
5-aminolevulinic acid-mediated photodynamic therapy on Hep-2 and MCF-7c3 cells. Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20070101
Cell-substrate topology upon ALA-PDT using variable-angle total internal reflection fluorescence microscopy (VA-TIRFM). Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20070101
Biochemical manipulation via iron chelation to enhance porphyrin production from porphyrin precursors. Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20070101
ALA and malignant glioma: fluorescence-guided resection and photodynamic treatment. Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20070101
Photodynamic therapy of vertebral metastases: evaluating tumor-to-neural tissue uptake of BPD-MA and ALA-PpIX in a murine model of metastatic human breast carcinoma. Photochemistry and photobiology 20070101
Study of protoporphyrin IX (PpIX) pharmacokinetics after topical application of 5-aminolevulinic acid in urethral condylomata acuminata. Photochemistry and photobiology 20070101
Oxidation decomposition of unsaturated fatty acids by singlet oxygen in phospholipid bilayer membranes. Journal of oleo science 20070101
Fluorescence-guided resection of metastatic brain tumors using a 5-aminolevulinic acid-induced protoporphyrin IX: pathological study. Brain tumor pathology 20070101
Regulation of 5-aminolevulinic acid-dependent protoporphyrin IX accumulations in human histiocytic lymphoma U937 cells. Physiological chemistry and physics and medical NMR 20070101
Photosensitized reduction of water to hydrogen using human serum albumin complexed with zinc-protoporphyrin IX. Journal of the American Chemical Society 20061220
Sonodynamic effects of protoporphyrin IX disodium salt on isolated sarcoma 180 cells. Ultrasonics 20061201
Fractionated illumination after topical application of 5-aminolevulinic acid on normal skin of hairless mice: the influence of the dark interval. Journal of photochemistry and photobiology. B, Biology 20061201
[5-ALA fluorescence guided tumor resection]. No to shinkei = Brain and nerve 20061201
[Fluorescence diagnosis and photodynamic therapy with 5-aminolevulinic acid induced protoporphyrin IX in gynecology: an overview]. Zentralblatt fur Gynakologie 20061201
How large is the [Fe(III)(protoporphyrin IX)]+ ion (hemin+) in the gas phase? The journal of physical chemistry. B 20061130
Mass spectrometry studies of demetallation of haemin by recombinant horse L chain apoferritin and its mutant (E 53,56,57,60 Q). FEBS letters 20061113
Involvement of both caspase-dependent and -independent pathways in apoptotic induction by hexaminolevulinate-mediated photodynamic therapy in human lymphoma cells. Apoptosis : an international journal on programmed cell death 20061101
The first structure from the SOUL/HBP family of heme-binding proteins, murine P22HBP. The Journal of biological chemistry 20061020
A study comparing endogenous protoporphyrin IX induced by 5-ALA and ALA-methyl ester with exogenous PpIX and PpIX dimethyl ester in photodynamic diagnosis of human nasopharyngeal carcinoma xenografts. International journal of oncology 20061001
Topical application of 5-aminolaevulinic acid, methyl 5-aminolaevulinate and hexyl 5-aminolaevulinate on normal human skin. The British journal of dermatology 20061001
The cytotoxic and genotoxic potential of 5-aminolevulinic acid on lymphocytes: a comet assay study. Cancer chemotherapy and pharmacology 20060901
Subcellular localization pattern of protoporphyrin IX is an important determinant for its photodynamic efficiency of human carcinoma and normal cell lines. Journal of photochemistry and photobiology. B, Biology 20060901
Protoporphyrin IX generation from delta-aminolevulinic acid elicits pulmonary artery relaxation and soluble guanylate cyclase activation. American journal of physiology. Lung cellular and molecular physiology 20060901
Heterogeneity of fluorescence in psoriasis after application of 5-aminolaevulinic acid: an immunohistochemical study. The British journal of dermatology 20060901
Methotrexate used in combination with aminolaevulinic acid for photodynamic killing of prostate cancer cells. British journal of cancer 20060821
Tumor cell lines resistant to ALA-mediated photodynamic therapy and possible tools to target surviving cells. International journal of oncology 20060801
A placebo-controlled randomized study on the clinical effectiveness, immunohistochemical changes and protoporphyrin IX accumulation in fractionated 5-aminolaevulinic acid-photodynamic therapy in patients with psoriasis. The British journal of dermatology 20060801
Possible role of creatine concentrations in the brain in regulating appetite and weight. Brain research 20060726
A new class of [2Fe-2S]-cluster-containing protoporphyrin (IX) ferrochelatases. The Biochemical journal 20060701
In vitro phototoxicity of 5-aminolevulinic acid and its methyl ester and the influence of barrier properties on their release from a bioadhesive patch. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20060701
Influence of administration methods on the accumulation of ALA-induced Pp-IX in mouse tongue tumors. Oral diseases 20060701
Fluorescence staining of human ovarian cancer tissue following application of 5-aminolevulinic acid: fluorescence microscopy studies. Lasers in surgery and medicine 20060601
ATP-binding cassette transporter G2 mediates the efflux of phototoxins on the luminal membrane of retinal capillary endothelial cells. Pharmaceutical research 20060601
The HA2 haemagglutinin domain of the lysine-specific gingipain (Kgp) of Porphyromonas gingivalis promotes micro-oxo bishaem formation from monomeric iron(III) protoporphyrin IX. Microbiology (Reading, England) 20060601
Integral spectrophotometric analysis of 5-aminolaevulinic acid-induced fluorescence cytology of the urinary bladder. BJU international 20060501
Nitric oxide-induced resistance to lethal photooxidative damage in a breast tumor cell line. Free radical biology & medicine 20060415
Fluorescence spectroscopy combined with 5-aminolevulinic acid-induced protoporphyrin IX fluorescence in detecting oral premalignancy. Journal of photochemistry and photobiology. B, Biology 20060403
In vitro percutaneous absorption and in vivo protoporphyrin IX accumulation in skin and tumors after topical 5-aminolevulinic acid application with enhancement using an erbium:YAG laser. Journal of pharmaceutical sciences 20060401
Characteristics of 5-aminolaevulinic acid-induced protoporphyrin IX fluorescence in human skin in vivo. Photodermatology, photoimmunology & photomedicine 20060401
Griseofulvin enhances the effect of aminolevulinic acid-based photodynamic therapy in vitro. Photomedicine and laser surgery 20060401
Polyamine conjugates of meso-tritolylporphyrin and protoporphyrin IX: potential agents for photodynamic therapy of cancers. Bioorganic & medicinal chemistry 20060301
Three-dimensional model of the human aromatase enzyme and density functional parameterization of the iron-containing protoporphyrin IX for a molecular dynamics study of heme-cysteinato cytochromes. Proteins 20060301
Role of vascular heme oxygenase in reduced myogenic reactivity following chronic hypoxia. Microcirculation (New York, N.Y. : 1994) 20060301
A direct and simultaneous detection of zinc protoporphyrin IX, free protoporphyrin IX, and fluorescent heme degradation product in red blood cell hemolysates. Free radical research 20060301
YC-1-like potentiation of NO-dependent activation of soluble guanylate cyclase by derivatives of protoporphyrin IX. Biochemistry. Biokhimiia 20060301
Arabidopsis ACCELERATED CELL DEATH2 modulates programmed cell death. The Plant cell 20060201
Inhibitory effect of piperlonguminine on melanin production in melanoma B16 cell line by downregulation of tyrosinase expression. Pigment cell research 20060201
Non-covalent modification of the heme-pocket of apomyoglobin by a 1,10-phenanthroline derivative. Bioorganic & medicinal chemistry letters 20060115
The pH-dependent conformational transition of beta-lactoglobulin modulates the binding of protoporphyrin IX. Biochimica et biophysica acta 20060101
Photobleaching kinetics, photoproduct formation, and dose estimation during ALA induced PpIX PDT of MLL cells under well oxygenated and hypoxic conditions. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20060101
Topical bioadhesive patch systems enhance selectivity of protoporphyrin IX accumulation. Photochemistry and photobiology 20060101
Use of ALA and ALA derivatives for optimizing ALA-based photodynamic therapy: a review of our experience. Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20060101
Regulation of porphyrin synthesis and photodynamic therapy in heavy metal intoxication. Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20060101
Induction of apoptosis by hexaminolevulinate-mediated photodynamic therapy in human colon carcinoma cell line 320DM. Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20060101
Repetitive photodynamic therapy of malignant brain tumors. Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20060101
Spectroscopic measurements of photoinduced processes in human skin after topical application of the hexyl ester of 5-aminolevulinic acid. Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20060101
Photodynamic therapy of nodular basal cell carcinoma with multifiber contact light delivery. Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20060101
Targeting of sebocytes by aminolevulinic acid-dependent photosensitization. Photochemistry and photobiology 20060101
Protoporphyrin IX level correlates with number of mitochondria, but increase in production correlates with tumor cell size. Photochemistry and photobiology 20060101
beta-Carotene and cigarette smoke condensate regulate heme oxygenase-1 and its repressor factor Bach1: relationship with cell growth. Antioxidants & redox signaling 20060101
Photodynamic therapies: principles and present medical applications. Bio-medical materials and engineering 20060101
Protoporphyrin IX fluorescence photobleaching and the response of rat Barrett's esophagus following 5-aminolevulinic acid photodynamic therapy. Photochemistry and photobiology 20060101
Topical 5-aminolevulinic acid mediated photodynamic therapy of superficial basal cell carcinoma using two light fractions with a two-hour interval: long-term follow-up. Acta dermato-venereologica 20060101
On the role of iron and one of its chelating agents in the production of protoporphyrin IX generated by 5-aminolevulinic acid and its hexyl ester derivative tested on an epidermal equivalent of human skin. Photochemistry and photobiology 20060101
Photodynamic diagnosis (PDD) using 5-aminolevulinic acid-supplemented cultures of human endometrial epithelial cells. Advances in medical sciences 20060101
Frataxin deficiency alters heme pathway transcripts and decreases mitochondrial heme metabolites in mammalian cells. Human molecular genetics 20051215
Targeting PBR by hexaminolevulinate-mediated photodynamic therapy induces apoptosis through translocation of apoptosis-inducing factor in human leukemia cells. Cancer research 20051201
Early neoplastic and metastatic mammary tumours of transgenic mice detected by 5-aminolevulinic acid-stimulated protoporphyrin IX accumulation. British journal of cancer 20051114
Functional characterization of the C-terminal domain of the cytochrome c maturation protein CcmE. The Journal of biological chemistry 20051104
Expression pattern and intensity of protoporphyrin IX induced by liposomal 5-aminolevulinic acid in rat pilosebaceous unit throughout hair cycle. Archives of dermatological research 20051101
Influence of light exposure on the kinetics of protoporphyrin IX formation in normal skin of hairless mice after application of 5-aminolevulinic acid methyl ester. The Journal of investigative dermatology 20051101
In vitro and ex vivo protoporphyrin IX expression induced by 5-aminolevulinic acid in human pilosebaceous unit. Journal of dermatological science 20051001
Induction of apoptosis-like mitochondrial impairment triggers antioxidant and Bcl-2-dependent keratinocyte differentiation. The Journal of investigative dermatology 20051001
Correlation between macroscopic fluorescence and protoporphyrin IX content in psoriasis and actinic keratosis following application of aminolevulinic acid. The Journal of investigative dermatology 20051001
Lack of effect of hyperoxia on photodynamic therapy and lipid peroxidation in three different cancer cell lines. Medical science monitor : international medical journal of experimental and clinical research 20051001
Lipid cubic phases for improved topical drug delivery in photodynamic therapy. Journal of controlled release : official journal of the Controlled Release Society 20050902
A continuous fluorimetric assay for protoporphyrinogen oxidase by monitoring porphyrin accumulation. Analytical biochemistry 20050901
[Intraoperative photodynamic diagnosis using 5-ALA for glioma surgery]. Nihon rinsho. Japanese journal of clinical medicine 20050901
Microcytic anemia, erythropoietic protoporphyria, and neurodegeneration in mice with targeted deletion of iron-regulatory protein 2. Blood 20050801
Topical glycerol monooleate/propylene glycol formulations enhance 5-aminolevulinic acid in vitro skin delivery and in vivo protophorphyrin IX accumulation in hairless mouse skin. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20050801
Determination of intracellular prolyl/glycyl proteases in intact living human cells and protoporphyrin IX production as a reporter system. Chemistry & biology 20050801
Photodynamic therapy of Walker tumors by multiple laser irradiation. Photomedicine and laser surgery 20050801
Size and surface charge effect of 5-aminolevulinic acid-containing liposomes on photodynamic therapy for cultivated cancer cells. Drug development and industrial pharmacy 20050801
Enhancement of the effect of 5-aminolevulinic acid-based photodynamic therapy by simultaneous hyperthermia. International journal of oncology 20050701
Reorganization of cytoskeleton induced by 5-aminolevulinic acid-mediated photodynamic therapy and its correlation with mitochondrial dysfunction. Lasers in surgery and medicine 20050601
Topical application of photofrin for photodynamic diagnosis of oral neoplasms. Plastic and reconstructive surgery 20050601
Residues stabilizing the heme moiety of the nitric oxide sensor soluble guanylate cyclase. European journal of pharmacology 20050418
The final catalytic step of cytochrome p450 aromatase: a density functional theory study. Journal of the American Chemical Society 20050413
Light scattering from intact cells reports oxidative-stress-induced mitochondrial swelling. Biophysical journal 20050401
Cell specific effects of polyunsaturated fatty acids on 5-aminolevulinic acid based photosensitization. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20050401
RNA expression profiling of normal and tumor cells following photodynamic therapy with 5-aminolevulinic acid-induced protoporphyrin IX in vitro. Molecular cancer therapeutics 20050401
Porphyrin-substrate binding to murine ferrochelatase: effect on the thermal stability of the enzyme. The Biochemical journal 20050315
Increased expression of the Abcg2 transporter during erythroid maturation plays a role in decreasing cellular protoporphyrin IX levels. Blood 20050315
Antifungal effect of 5-aminolevulinic acid PDT in Trichophyton rubrum. Mycoses 20050301
Formation of a misfolded conformation during refolding of HRPA1 in the presence of calcium. Biochimica et biophysica acta 20050214
ABCG2-mediated transport of photosensitizers: potential impact on photodynamic therapy. Cancer biology & therapy 20050201
Kinetics of protoporphyrin IX formation in rat oral mucosa and skin after application of 5-aminolevulinic acid and its methylester. Photochemistry and photobiology 20050101
Potential role of heme oxygenase-1 in the progression of rat adjuvant arthritis. Laboratory investigation; a journal of technical methods and pathology 20050101
Self-sensitized photodegradation of membrane-bound protoporphyrin mediated by chain lipid peroxidation: inhibition by nitric oxide with sustained singlet oxygen damage. Photochemistry and photobiology 20050101
Specific intensity imaging for glioblastoma and neural cell cultures with 5-aminolevulinic acid-derived protoporphyrin IX. Journal of neuro-oncology 20050101
A spectrophotometric micromethod for determining erythrocyte protoporphyrin-IX in whole blood or erythrocytes. Clinical chemistry and laboratory medicine 20050101
Systemic suppression of the contact hypersensitivity by the products of protoporphyrin IX photooxidation. Photochemistry and photobiology 20050101
[The role of lipid peroxidation products in the effect of He-Ne laser on human blood leukocytes]. Biofizika 20050101
Inner-sphere electron-transfer reorganization energies of zinc porphyrins. Journal of the American Chemical Society 20041201
In vitro metabolism of 5-ALA esters derivatives in hairless mice skin homogenate and in vivo PpIX accumulation studies. Pharmaceutical research 20041201
Effect of oil-in-water emulsions on 5-aminolevulinic acid uptake and metabolism to PpIX in cultured MCF-7 cells. Pharmaceutical research 20041201
[Fluorescence imaging technique: diagnostic and therapeutic interest in gynecology]. Journal de gynecologie, obstetrique et biologie de la reproduction 20041201
RRM analysis of protoporphyrinogen oxidase. Australasian physical & engineering sciences in medicine 20041201
The mitochondrion--an organelle commonly involved in programmed cell death in Arabidopsis thaliana. The Plant journal : for cell and molecular biology 20041101
In vitro studies on thioether bond formation between Hydrogenobacter thermophilus apocytochrome c(552) with metalloprotoporphyrin derivatives. The Journal of biological chemistry 20041029
Crystal structure of arachidonic acid bound to a mutant of prostaglandin endoperoxide H synthase-1 that forms predominantly 11-hydroperoxyeicosatetraenoic acid. The Journal of biological chemistry 20041008
Optimised expression and purification of recombinant human indoleamine 2,3-dioxygenase. Protein expression and purification 20041001
Phototoxicity of exogenous protoporphyrin IX and delta-aminolevulinic acid in the photo hen's egg test. Photodermatology, photoimmunology & photomedicine 20041001
Phototoxicity of 5-aminolevulinic acid in the HeLa cell line as an indicative measure of photodynamic effect after topical administration to gynecological lesions of intraepithelial form. Pharmaceutical research 20041001
The monitoring of the accumulation of protoporphyrin IX in Walker tumours by subcutaneous administration of delta-aminolevulinic acid. Journal of experimental therapeutics & oncology 20041001
Photosensitization with protoporphyrin IX inhibits attachment of cancer cells to a substratum. Biochemical and biophysical research communications 20040917
Synthesis and photochemical properties of a novel iron-sulfur-nitrosyl cluster derivatized with the pendant chromophore protoporphyrin IX. Inorganic chemistry 20040906
Mechanism of internal anal sphincter relaxation by CORM-1, authentic CO, and NANC nerve stimulation. American journal of physiology. Gastrointestinal and liver physiology 20040901
Hexaminolevulinate-induced fluorescence endoscopy in patients with rectal adenoma and cancer: a pilot study. Gastrointestinal endoscopy 20040901
Mechanism of in vitro heme-induced LDL oxidation: effects of antioxidants. European journal of clinical investigation 20040901
Confocal endomicroscopic imaging of normal and neoplastic human tongue tissue using ALA-induced-PPIX fluorescence: a preliminary study. Oncology reports 20040801
delta-Aminolaevulinic acid mediated photodynamic antimicrobial chemotherapy on Pseudomonas aeruginosa planktonic and biofilm cultures. Journal of photochemistry and photobiology. B, Biology 20040719
Crystal structure of the ascorbate peroxidase-salicylhydroxamic acid complex. Biochemistry 20040713
In vitro evaluation of the cytotoxic and mutagenic potential of the 5-aminolevulinic acid hexylester-mediated photodynamic therapy. Mutation research 20040711
Mapping ALA-induced PPIX fluorescence in normal brain and brain tumour using confocal fluorescence microscopy. International journal of oncology 20040701
The use of digitized endoscopic imaging of 5-ALA-induced PPIX fluorescence to detect and diagnose oral premalignant and malignant lesions in vivo. International journal of cancer 20040610
Proximal and distal influences on ligand binding kinetics in microperoxidase and heme model compounds. Biochemistry 20040608
The stem cell marker Bcrp/ABCG2 enhances hypoxic cell survival through interactions with heme. The Journal of biological chemistry 20040604
Fluorescence diagnosis: a novel method to guide radical inguinal lymph node dissection in penile cancer. World journal of urology 20040601
Influence of CaNa2 EDTA on topical 5-aminolaevulinic acid photodynamic therapy. Chinese medical journal 20040601
A novel Arabidopsis thaliana protein is a functional peripheral-type benzodiazepine receptor. Plant & cell physiology 20040601
Characterization of eight barley xantha-f mutants deficient in magnesium chelatase. Plant physiology and biochemistry : PPB 20040601
5-aminolevulinic acid-based photodynamic therapy in leukemia cell HL60. Photochemistry and photobiology 20040601
Differentiation-dependent photodynamic therapy regulated by porphobilinogen deaminase in B16 melanoma. British journal of cancer 20040504
ALA (5-aminolevulinic acid)-induced protoporphyrin IX fluorescence in the endoscopic diagnostic and control of pharyngo-laryngeal cancer. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 20040501
Heme-iron increases levels of AP65-mediated adherence by Trichomonas vaginalis. Microbial pathogenesis 20040501
On the selectivity of 5-aminolevulinic acid-induced protoporphyrin IX formation. Current medicinal chemistry. Anti-cancer agents 20040501
Laparoscopic fluorescence detection of ovarian carcinoma metastases using 5-aminolevulinic acid-induced protoporphyrin IX. Cancer 20040415
Comparison of high- vs low-dose 5-aminolevulinic acid for photodynamic therapy of Barrett's esophagus. Surgical endoscopy 20040301
Effect of elevating the skin temperature during topical ALA application on in vitro ALA penetration through mouse skin and in vivo PpIX production in human skin. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20040301
Photodynamic inhibition of enzymatic detachment of human cancer cells from a substratum. Biochimica et biophysica acta 20040105
In situ assessment of porphyrin photosensitizers in Propionibacterium acnes. Zeitschrift fur Naturforschung. C, Journal of biosciences 20040101
Photodynamic therapy of prostate cancer by means of 5-aminolevulinic acid-induced protoporphyrin IX - in vivo experiments on the dunning rat tumor model. Urologia internationalis 20040101
Effect of 5-aminolevulinic acid on kinetics of protoporphyrin IX production in CHO cells. Folia histochemica et cytobiologica 20040101
5-aminolevulinic acid ester-induced protoporphyrin IX in a murine melanoma cell line. Lasers in medical science 20040101
[5-Aminolevulinic acid (ALA) and its applications in neurosurgery]. Neurologia i neurochirurgia polska 20040101
Increased brain tumor resection using fluorescence image guidance in a preclinical model. Lasers in surgery and medicine 20040101
Time-dependent hexaminolaevulinate induced protoporphyrin IX distribution after topical application in patients with cervical intraepithelial neoplasia: A fluorescence microscopy study. Lasers in surgery and medicine 20040101
Heme oxygenase-2 products activate IKCa: role of CO and iron in guinea pig portal vein smooth muscle cells. Journal of muscle research and cell motility 20040101
Erythrocytes-the 'house elves' of photodynamic therapy. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20040101
Phototoxicity of protoporphyrin IX, diarginine diprotoporphyrinate and N,N-diphenylalanyl protoporphyrin toward human fibroblasts and keratinocytes in vitro: effect of 5-methoxypsoralen. Photochemistry and photobiology 20040101
Effect of 5-aminolevulinic acid (ALA) doses and oestrogen/progesterone on protoporphyrin IX (ppIX) accumulation in human endometrial epithelial cells. Roczniki Akademii Medycznej w Bialymstoku (1995) 20040101
Protoporphyrin IX-accumulation in human tumor cells following topical ALA- and h-ALA-application in vivo. Cancer letters 20031208
Porphyromonas gingivalis gingipains: the molecular teeth of a microbial vampire. Current protein & peptide science 20031201
Protoporphyrin IX binding and transport by recombinant mouse PBR. Biochemical and biophysical research communications 20031128
In vitro tests of the validity of singlet oxygen luminescence measurements as a dose metric in photodynamic therapy. Cancer research 20031115
In vivo fluorescence kinetics and photodynamic therapy in condylomata acuminata. The British journal of dermatology 20031101
Protoporphyrin IX production and its photodynamic effects on glioma cells, neuroblastoma cells and normal cerebellar granule cells in vitro with 5-aminolevulinic acid and its hexylester. Cancer letters 20031028
A physiological role for protoporphyrin IX photodynamic action in the rat Harderian gland? Acta physiologica Scandinavica 20031001
[Precancerous conditions in the urothelium. Early detection and molecular understanding through endoscopic fluorescence diagnosis]. Der Pathologe 20031001
Preparation of heme-free soluble guanylate cyclase. Protein expression and purification 20030901
Metalloporphyrin probes for antimalarial drug action. Journal of inorganic biochemistry 20030901
Monitoring in situ dosimetry and protoporphyrin IX fluorescence photobleaching in the normal rat esophagus during 5-aminolevulinic acid photodynamic therapy. Photochemistry and photobiology 20030901
Selective accumulation of ALA-induced PpIX and photodynamic effect in chemically induced hepatocellular carcinoma. British journal of cancer 20030818
Hemoglobin metabolites mimic benzodiazepines and are possible mediators of hepatic encephalopathy. Blood 20030815
Comparison of aminolevulinic acid and hexylester aminolevulinate induced protoporphyrin IX distribution in human bladder cancer. The Journal of urology 20030801
Endoscopic fluorescence detection of intraepithelial neoplasia in Barrett's esophagus after oral administration of aminolevulinic acid. Endoscopy 20030801
Comparative antistreptococcal activity of photobactericidal agents. Journal of chemotherapy (Florence, Italy) 20030801
Coordination complex between haemin and parallel-quadruplexed d(TTAGGG). Chemical communications (Cambridge, England) 20030721
Fluorescence endoscopy for the detection of low and high grade dysplasia in ulcerative colitis using systemic or local 5-aminolaevulinic acid sensitisation. Gut 20030701
Repeated exposure to blue light does not improve psoriasis. Journal of the American Academy of Dermatology 20030701
Photodynamic effects of 5-aminolevulinic acid and its hexylester on several cell lines. Sheng wu hua xue yu sheng wu wu li xue bao Acta biochimica et biophysica Sinica 20030701
The effect of an iron chelating agent on protoporphyrin IX levels and phototoxicity in topical 5-aminolaevulinic acid photodynamic therapy. The British journal of dermatology 20030701
Aminolaevulinic acid-induced protoporphyrin IX pharmacokinetics in central and peripheral arteries of the rat. Photochemistry and photobiology 20030701
Specificity of photosensitizer accumulation in undifferentiated versus differentiated colon carcinoma cells. Cancer letters 20030630
Photodynamic diagnosis of ovarian cancer using hexaminolaevulinate: a preclinical study. British journal of cancer 20030602
Biosynthesis of chlorophylls from protoporphyrin IX. Natural product reports 20030601
Fluorescence microspectroscopy technique for the study of intracellular protoporphyrin IX dynamics. Applied spectroscopy 20030601
Idebenone treatment in Friedreich patients: one-year-long randomized placebo-controlled trial. Neurology 20030527
Idebenone treatment in Friedreich's ataxia: neurological, cardiac, and biochemical monitoring. Neurology 20030527
Evaluation of dipeptide-derivatives of 5-aminolevulinic acid as precursors for photosensitizers in photodynamic therapy. Bioorganic & medicinal chemistry 20030403
A randomised, double-blind, placebo-controlled trial of photodynamic therapy using 5-aminolaevulinic acid for the treatment of cervical intraepithelial neoplasia. International journal of cancer 20030301
Fluorescence confocal microscopy and image analysis of bladder cancer using 5-aminolevulinic acid. International journal of oncology 20030301
Dose and timing of the first light fraction in two-fold illumination schemes for topical ALA-mediated photodynamic therapy of hairless mouse skin. Photochemistry and photobiology 20030301
GUN4, a regulator of chlorophyll synthesis and intracellular signaling. Science (New York, N.Y.) 20030207
High-resolution structure and biochemical properties of a recombinant Proteus mirabilis catalase depleted in iron. Proteins 20030201
Comparison of the formation of N-alkylprotoporphyrin IX after interaction of porphyrinogenic xenobiotics with single cDNA-expressed human P450 enzymes in microsomes prepared from baculovirus-infected insect cells and human lymphoblastoid cell lines. Drug metabolism and disposition: the biological fate of chemicals 20030201
A study of 5-aminolevulinic acid and its methyl ester used in in vitro and in vivo systems of human bladder cancer. International journal of oncology 20030201
The importance of porphyrin distortions for the ferrochelatase reaction. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20030201
Phototoxic effects of 635-nm light on canine transitional cell carcinoma cells incubated with 5-aminolevulinic acid. American journal of veterinary research 20030201
Chloroplast to nucleus communication triggered by accumulation of Mg-protoporphyrinIX. Nature 20030102
Pharmacology of protoporphyrin IX in nude mice after application of ALA and ALA esters. International journal of cancer 20030101
Time gated fluorescence spectroscopy in Barrett's oesophagus. Gut 20030101
Time-resolved microspectrofluorometry and fluorescence lifetime imaging of photosensitizers using picosecond pulsed diode lasers in laser scanning microscopes. Journal of biomedical optics 20030101
Acceleration of ALA-induced PpIX fluorescence development in the oral mucosa. Lasers in surgery and medicine 20030101
A spectroscopic study of the photobleaching of protoporphyrin IX in solution. Lasers in medical science 20030101
[Photodynamic damage of yeast subcellular fraction induced by elevated levels of endogenous protoporphyrin IX]. Mikrobiologiia 20030101
Fluorescence-guided resections of malignant gliomas--an overview. Acta neurochirurgica. Supplement 20030101
Detection of protoporphyrin IX in envelope membranes of pea chloroplasts. Biochemical and biophysical research communications 20021220
Protoporphyrin-IX accumulation and cutaneous tumor regression in mice using a ferrochelatase inhibitor. Cancer letters 20021210
Gene expression pattern following photodynamic treatment of the carcinoma cell line A-431 analysed by cDNA arrays. International journal of oncology 20021201
Effects on free radical generation by ligands of the peripheral benzodiazepine receptor in cultured neural cells. Journal of neurochemistry 20021201
Porphyrins as early biomarkers for arsenic exposure in animals and humans. Cellular and molecular biology (Noisy-le-Grand, France) 20021201
Bilirubin and ferritin as protectors against hemin-induced oxidative stress in rat liver. Cellular and molecular biology (Noisy-le-Grand, France) 20021201
Two course illuminating scheme improves aminolevulinic acid photodynamic therapy in cell cultures. Cellular and molecular biology (Noisy-le-Grand, France) 20021201
Production of protoporphyrin IX from 5-aminolevulinic acid and two of its esters in cells in vitro and tissues in vivo. Cellular and molecular biology (Noisy-le-Grand, France) 20021201
Improving the use of 5-aminolevulinic acid (ALA)-induced protoporphyrin IX (PPIX) for the gastrointestinal tract by esterification--an in vitro study. Cellular and molecular biology (Noisy-le-Grand, France) 20021201
Differentiation enhances aminolevulinic acid-dependent photodynamic treatment of LNCaP prostate cancer cells. British journal of cancer 20021118
Hyperresistance to photosensitized lipid peroxidation and apoptotic killing in 5-aminolevulinate-treated tumor cells overexpressing mitochondrial GPX4. Free radical biology & medicine 20021115
[Fluorescence staining of oral and laryngeal cancer after application of 5-aminolevulinic acid]. Laryngo- rhino- otologie 20021101
Metabolic characterization of tumor cell-specific protoporphyrin IX accumulation after exposure to 5-aminolevulinic acid in human colonic cells. Photochemistry and photobiology 20021101
Transfer of protoporphyrin IX between cells. Photochemistry and photobiology 20021101
Comparison of the photodynamic effect of exogenous photoprotoporphyrin and protoporphyrin IX on PAM 212 murine keratinocytes. Photochemistry and photobiology 20021101
Detection of neoplasms in the oral cavity by digitized endoscopic imaging of 5-aminolevulinic acid-induced protoporphyrin IX fluorescence. International journal of oncology 20021001
Detection of high-grade dysplasia in Barrett's esophagus by spectroscopy measurement of 5-aminolevulinic acid-induced protoporphyrin IX fluorescence. Gastrointestinal endoscopy 20021001
Temperature effect on accumulation of protoporphyrin IX after topical application of 5-aminolevulinic acid and its methylester and hexylester derivatives in normal mouse skin. Photochemistry and photobiology 20021001
Noninvasive fluorescence excitation spectroscopy during application of 5-aminolevulinic acid in vivo. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20021001
Photosensitizing effect of protoporphyrin IX in pigmented melanoma of mice. Biochemical and biophysical research communications 20020927
Comparison of 5-aminolevulinic acid and its hexylester mediated photodynamic action on human hepatoma cells. Sheng wu hua xue yu sheng wu wu li xue bao Acta biochimica et biophysica Sinica 20020901
Topical application of 5-aminolevulinic acid and its methylester, hexylester and octylester derivatives: considerations for dosimetry in mouse skin model. Photochemistry and photobiology 20020901
Enhanced transdermal transport by electroporation using anionic lipids. Journal of controlled release : official journal of the Controlled Release Society 20020821
Timing of 5-aminolaevulinic acid-induced photodynamic therapy for the treatment of patients with Barrett's oesophagus. Journal of photochemistry and photobiology. B, Biology 20020801
Effect of prostaglandin-J(2) on VEGF synthesis depends on the induction of heme oxygenase-1. Antioxidants & redox signaling 20020801
Porphyrin accumulation induced by 5-aminolaevulinic acid esters in tumour cells growing in vitro and in vivo. British journal of cancer 20020715
Weekly topical application of methyl aminolevulinate followed by light exposure delays the appearance of UV-induced skin tumours in mice. Archives of dermatological research 20020701
In vivo pharmacokinetics of 8-aminolevulinic acid-induced protoporphyrin IX during pre- and post-photodynamic therapy in 7,12-dimethylbenz(a)nthracene-treated skin carcinogenesis in Swiss mice: a comparison by three-compartment model. Photochemistry and photobiology 20020701
Systemic photodynamic therapy with aminolevulinic acid induces apoptosis in lesional T lymphocytes of psoriatic plaques. The Journal of investigative dermatology 20020701
PDT effects of m-THPC and ALA, phototoxicity and apoptosis. Apoptosis : an international journal on programmed cell death 20020601
Photodynamic therapy of human Barrett's cancer using 5-aminolaevulinic acid-induced protoporphyrin IX: an in-vivo dosimetry study in athymic nude mice. European journal of gastroenterology & hepatology 20020601
Erythroid differentiation and protoporphyrin IX down-regulate frataxin expression in Friend cells: characterization of frataxin expression compared to molecules involved in iron metabolism and hemoglobinization. Blood 20020515
Clinical pharmacokinetics of 5-aminolevulinic acid in healthy volunteers and patients at high risk for recurrent bladder cancer. The Journal of pharmacology and experimental therapeutics 20020501
In vitro/in vivo correlations between transdermal delivery of 5-aminolaevulinic acid and cutaneous protoporphyrin IX accumulation and effect of formulation. The British journal of dermatology 20020501
Protoporphyrin IX fluorescence kinetics in UV-induced tumours and normal skin of hairless mice after topical application of 5-aminolevulinic acid methyl ester. Journal of photochemistry and photobiology. B, Biology 20020501
Tumor PO(2) changes during photodynamic therapy depend upon photosensitizer type and time after injection. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20020501
Protoporphyrin IX photodynamic therapy for synovitis. Arthritis and rheumatism 20020501
In vitro photodynamic therapy of nasopharyngeal carcinoma using 5-aminolevulinic acid. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20020501
Aminolaevulinic acid-induced photodynamic therapy: cellular responses to glucose starvation. British journal of cancer 20020422
Histidine pK(a) shifts and changes of tautomeric states induced by the binding of gallium-protoporphyrin IX in the hemophore HasA(SM). Protein science : a publication of the Protein Society 20020401
The fluorescence biodistribution and kinetics of aminolevulinic acid induced protoporphyrin IX in the bladder of a rat model with orthotopic urothelial carcinoma. The Journal of urology 20020401
Detection of female lower genital tract dysplasia using orally administered 5-aminolevulinic acid induced protoporphyrin IX: a preliminary study. Gynecologic oncology 20020401
Localization and staging of cervical intraepithelial neoplasia using double ratio fluorescence imaging. Journal of biomedical optics 20020401
Quantitative model calculation of the time-dependent protoporphyrin IX concentration in normal human epidermis after delivery of ALA by passive topical application or lontophoresis. Photochemistry and photobiology 20020401
Effects of porphyrins and inorganic iron on the growth of Prevotella intermedia. FEMS microbiology letters 20020319
The atomic structure of human methemalbumin at 1.9 A. Biochemical and biophysical research communications 20020308
Asp-225 and glu-375 in autocatalytic attachment of the prosthetic heme group of lactoperoxidase. The Journal of biological chemistry 20020301
Antitumor agents. Part 209: Pheophorbide-a derivatives as photo-Independent cytotoxic agents. Bioorganic & medicinal chemistry 20020301
Measurement of ferrochelatase activity using a novel assay suggests that plastids are the major site of haem biosynthesis in both photosynthetic and non-photosynthetic cells of pea (Pisum sativum L.). The Biochemical journal 20020301
Inhibition of nitric oxide-dependent activation of soluble guanylyl cyclase by the antimalarial drug, artemisinin. European journal of pharmacology 20020301
Laparoscopic fluorescence diagnosis for intraabdominal fluorescence targeting of peritoneal carcinosis experimental studies. Annals of surgery 20020201
PpIX fluorescence kinetics and increased skin damage after intracutaneous injection of 5-aminolevulinic acid and repeated illumination. The Journal of investigative dermatology 20020201
Potential efficacy of a delta 5-aminolevulinic acid thermosetting gel formulation for use in photodynamic therapy of lesions of the gastrointestinal tract. Pharmacological research 20020201
Systemic component of protoporphyrin IX production in nude mouse skin upon topical application of aminolevulinic acid depends on the application conditions. Photochemistry and photobiology 20020201
A comparative study of normal inspection, autofluorescence and 5-ALA-induced PPIX fluorescence for oral cancer diagnosis. International journal of cancer 20020110
The influence of photodynamic reaction on R2C cells. Folia histochemica et cytobiologica 20020101
Amino acid and peptide conjugates of protoporphyrin: preparation and analysis by high-performance liquid chromatography, high-performance liquid chromatography/electrospray ionization mass spectrometry and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Rapid communications in mass spectrometry : RCM 20020101
Kinetics of 5-aminolevulinic acid-induced fluorescence in organ cultures of bronchial epithelium and tumor. Respiration; international review of thoracic diseases 20020101
Porphyrinogenic xenobiotic-induced N-alkylprotoporphyrin IX formation: a bioassay utilizing chick embryo hepatic ferrochelatase. Journal of pharmacological and toxicological methods 20020101
[Fluorescent photobleaching of endogenous protoporphyrin IX in yeast cells]. Biofizika 20020101
Comparison of normal piglet bladder damage after PDT with oral or intravesical administration of ALA. Lasers in medical science 20020101
Antioxidant inhibition of porphyrin-induced cellular phototoxicity. Journal of photochemistry and photobiology. B, Biology 20011231
Heme-regulated eIF2alpha kinase (HRI) is required for translational regulation and survival of erythroid precursors in iron deficiency. The EMBO journal 20011203
The influence of UV exposure on 5-aminolevulinic acid-induced protoporphyrin IX production in skin. Photochemistry and photobiology 20011201
Intraoperative fluorescence visualization of the parathyroid gland in rats. Endocrinology 20011101
Fluorescence induced with 5-aminolevulinic acid for the endoscopic detection and follow-up of esophageal lesions. Gastrointestinal endoscopy 20011101
Effects of 5-aminolaevulinic acid on human ovarian cancer cells and human vascular endothelial cells in vitro. Journal of photochemistry and photobiology. B, Biology 20011101
Protoporphyrin IX distribution following local application of 5-aminolevulinic acid and its esterified derivatives in the tissue layers of the normal rat colon. British journal of cancer 20011101
The effects of 5-aminolevulinic acid esters on protoporphyrin IX production in human adenocarcinoma cell lines. Photochemistry and photobiology 20011101
ALA and ALA hexyl ester-induced porphyrin synthesis in chemically induced skin tumours: the role of different vehicles on improving photosensitization. British journal of cancer 20011101
[Intraoperative photodynamic diagnosis of human glioma using ALA induced protoporphyrin IX]. No shinkei geka. Neurological surgery 20011101
In vitro and in vivo expression of protoporphyrin IX induced by lipophilic 5-aminolevulinic acid derivatives. Journal of dermatological science 20011001
Photodynamic effects induced by aminolevulinic acid esters on human cervical carcinoma cells in culture. Photochemistry and photobiology 20011001
Isolation and characterization of a cDNA from soybean and its homolog from Escherichia coli, which both complement the light sensitivity of Escherichia coli hemH mutant strain VS101. Genes & genetic systems 20011001
ALA- and ALA-hexylester-induced protoporphyrin IX fluorescence and distribution in multicell tumour spheroids. British journal of cancer 20010901
Autofluorescence imaging to optimize 5-ALA-induced fluorescence endoscopy of bladder carcinoma. Urology 20010901
Diagnostic efficacy of fluorescence cystoscopy for detection of urothelial neoplasms. Journal of endourology 20010901
In vivo pharmacokinetics of protoporphyrin IX accumulation following intracutaneous injection of 5-aminolevulinic acid. Journal of photochemistry and photobiology. B, Biology 20010815
Fluorescence spectroscopy of normal mouse skin exposed to 5-aminolaevulinic acid and red light. Journal of photochemistry and photobiology. B, Biology 20010815
Evaluation of protoporphyrin IX production, phototoxicity and cell death pathway induced by hexylester of 5-aminolevulinic acid in Reh and HPB-ALL cells. Cancer letters 20010810
5-Aminolevulinic acid-based photochemical internalization of the immunotoxin MOC31-gelonin generates synergistic cytotoxic effects in vitro. Photochemistry and photobiology 20010801
A mathematical evaluation of dose-dependent PpIX fluorescence kinetics in vivo. Photochemistry and photobiology 20010801
Oral aminolevulinic acid induces protoporphyrin IX fluorescence in psoriatic plaques and peripheral blood cells. Photochemistry and photobiology 20010801
The role of the peripheral benzodiazepine receptor in the apoptotic response to photodynamic therapy. Photochemistry and photobiology 20010801
Heme oxygenase-2 interaction with metalloporphyrins: function of heme regulatory motifs. Antioxidants & redox signaling 20010801
5-Aminolaevulinic acid-mediated photodynamic therapy in multidrug resistant leukemia cells. Journal of photochemistry and photobiology. B, Biology 20010701
The photosensitizing effect of the photoproduct of protoporphyrin IX. Journal of photochemistry and photobiology. B, Biology 20010701
Optimization of differential photodynamic effectiveness between normal and tumor urothelial cells using 5-aminolevulinic acid-induced protoporphyrin IX as sensitizer. International journal of cancer 20010601
Relaxometric characterization of human hemalbumin. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20010601
Substitution of murine ferrochelatase glutamate-287 with glutamine or alanine leads to porphyrin substrate-bound variants. The Biochemical journal 20010515
Antioxidants inhibit indoleamine 2,3-dioxygenase in IFN-gamma-activated human macrophages: posttranslational regulation by pyrrolidine dithiocarbamate. Journal of immunology (Baltimore, Md. : 1950) 20010515
Evaluation on the adsorption capabilities of new chemically modified polymeric adsorbents with protoporphyrin IX. Journal of chromatography. A 20010511
Photodynamic DNA damage mediated by delta-aminolevulinic acid-induced porphyrins. Carcinogenesis 20010501
Photomodification of the electrical properties of the plasma membrane: a comparison between 6 different membrane-active photosensitizers. The Journal of membrane biology 20010501
A quantitative assessment of protoporphyrin IX metabolism and phototoxicity in human skin following dose-controlled delivery of the prodrugs 5-aminolaevulinic acid and 5-aminolaevulinic acid-n-pentylester. The British journal of dermatology 20010501
On the pharmacokinetics of topically applied 5-aminolevulinic acid and two of its esters. International journal of cancer 20010401
Synergistic toxicity of delta-aminolaevulinic acid-induced protoporphyrin IX used for photodiagnosis and hypericum extract, a herbal antidepressant. The British journal of dermatology 20010401
Girard's reagent P derivative of beta-Apo-8'-carotenal: a potent photoprotective agent. Photochemistry and photobiology 20010401
Routine experimental system for defining conditions used in photodynamic therapy and fluorescence photodetection of (non-) neoplastic epithelia. Journal of biomedical optics 20010401
Fluorescence staining of oral cancer using a topical application of 5-aminolevulinic acid: fluorescence microscopic studies. Journal of photochemistry and photobiology. B, Biology 20010401
Modulator of heme biosynthesis induces apoptosis in leukemia cells. Journal of clinical laser medicine & surgery 20010401
Mechanisms involved in the blunted nitric oxide-cGMP pathway in hypertensive TGR(mREN2)27 rats. European journal of pharmacology 20010309
New Heck-type reaction applied to the synthesis of protoporphyrin-IX derivatives. Organic letters 20010222
Endogenous production of protoporphyrin IX induced by 5-aminolevulinic acid in leukemia cells. Acta pharmacologica Sinica 20010201
A plastidic ABC protein involved in intercompartmental communication of light signaling. Genes & development 20010101
Porphyrin bleaching and PDT-induced spectral changes are irradiance dependent in ALA-sensitized normal rat skin in vivo. Photochemistry and photobiology 20010101
Light irradiation increases embryotoxicity of photodynamic therapy sensitizers (5-aminolevulinic acid and protoporphyrin IX) in chick embryos. Reproductive toxicology (Elmsford, N.Y.) 20010101
Tissue distribution and penetration of 5-ALA induced fluorescence in an amelanotic melanoma after topical application. Anticancer research 20010101
Studies on the effect of photodynamic therapy on in vitro cultured neoplastic cells. Folia histochemica et cytobiologica 20010101
An affordable, portable fluorescence imaging device for skin lesion detection using a dual wavelength approach for image contrast enhancement and aminolaevulinic acid-induced protoporphyrin IX. Part I. Design, spectral and spatial characteristics. Lasers in medical science 20010101
An affordable, portable fluorescence imaging device for skin lesion detection using a dual wavelength approach for image contrast enhancement and aminolaevulinic acid-induced protoporphyrin IX. Part II. In vivo testing. Lasers in medical science 20010101
Fractionated illumination for oesophageal ALA-PDT: effect on blood flow and PpIX formation. Lasers in medical science 20010101
Can autofluorescence demarcate basal cell carcinoma from normal skin? A comparison with protoporphyrin IX fluorescence. Acta dermato-venereologica 20010101
A key role for the mitochondrial benzodiazepine receptor in cellular photosensitisation with delta-aminolaevulinic acid. European journal of pharmacology 20001013
Topological alteration of the CYP3A4 active site by the divalent cation Mg(2+). Drug metabolism and disposition: the biological fate of chemicals 20001001
The morphological changes in rat bladder after photodynamic therapy with 5-aminolaevulinic acid-induced protoporphyrin IX. BJU international 20000701
Non-iron metalloporphyrins: potent antibacterial compounds that exploit haem/Hb uptake systems of pathogenic bacteria. Molecular microbiology 19990101
Influence of a haematoporphyrin derivative on the protoporphyrin IX synthesis and photodynamic effect after 5-aminolaevulinic acid sensitization in human colon carcinoma cells. British journal of cancer 19970101
Photodynamic therapy (PDT) and photodiagnosis (PD) using endogenous photosensitization induced by 5-aminolevulinic acid (ALA): mechanisms and clinical results. Journal of clinical laser medicine & surgery 19961001
Properties