DigitoXin, USP
Title | Journal |
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Identification of anti-viral activity of the cardenolides, Na(+)/K(+)-ATPase inhibitors, against porcine transmissible gastroenteritis virus. | Toxicology and applied pharmacology 20171001 |
Heterogeneous transport of digitalis-like compounds by P-glycoprotein in vesicular and cellular assays. | Toxicology in vitro : an international journal published in association with BIBRA 20160401 |
Utilization of human nuclear receptors as an early counter screen for off-target activity: a case study with a compendium of 615 known drugs. | Toxicological sciences : an official journal of the Society of Toxicology 20150601 |
A novel cell-based high-throughput screen for inhibitors of HIV-1 gene expression and budding identifies the cardiac glycosides. | The Journal of antimicrobial chemotherapy 20140401 |
Interaction of digitalis-like compounds with p-glycoprotein. | Toxicological sciences : an official journal of the Society of Toxicology 20130201 |
Ouabain, a cardiac glycoside, inhibits the Fanconi anemia/BRCA pathway activated by DNA interstrand cross-linking agents. | PloS one 20130101 |
Analysis of drug interactions with modified proteins by high-performance affinity chromatography: binding of glibenclamide to normal and glycated human serum albumin. | Journal of chromatography. A 20121123 |
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine. | Bioorganic & medicinal chemistry 20121115 |
Digitoxin and a synthetic monosaccharide analog inhibit cell viability in lung cancer cells. | Toxicology and applied pharmacology 20120101 |
Assembly of digitoxin by gold(I)-catalyzed glycosidation of glycosyl o-alkynylbenzoates. | The Journal of organic chemistry 20111202 |
Termination of refractory focal status epilepticus by the P-glycoprotein inhibitor verapamil. | European journal of neurology 20111201 |
Antiherpes activity of glucoevatromonoside, a cardenolide isolated from a Brazilian cultivar of Digitalis lanata. | Antiviral research 20111001 |
Arrhythmogenic adverse effects of cardiac glycosides are mediated by redox modification of ryanodine receptors. | The Journal of physiology 20111001 |
Biotransformation of extracted digitoxin from Digitalis lanata by Streptomyces. | Die Pharmazie 20110601 |
Synthesis and evaluation of cardiac glycoside mimics as potential anticancer drugs. | Bioorganic & medicinal chemistry 20110401 |
HPLC method validation for Digitalis and its analogue by pulsed amperometric detection. | Journal of pharmaceutical and biomedical analysis 20110105 |
Ex vivo activity of cardiac glycosides in acute leukaemia. | PloS one 20110101 |
Cardiac glycosides potently inhibit C-reactive protein synthesis in human hepatocytes. | Biochemical and biophysical research communications 20100326 |
Cytotoxic effects of cardiac glycosides in colon cancer cells, alone and in combination with standard chemotherapeutic drugs. | Journal of natural products 20091101 |
Digitoxin elicits anti-inflammatory and vasoprotective properties in endothelial cells: Therapeutic implications for the treatment of atherosclerosis? | Atherosclerosis 20091001 |
Use of digitoxin and digoxin as internal standards in HPLC analysis of triterpene saponin-containing extracts. | Phytochemical analysis : PCA 20090101 |
Cardiac glycosides induce cell death in human cells by inhibiting general protein synthesis. | PloS one 20090101 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. | Journal of medicinal chemistry 20081113 |
Digoxin-specific Fab fragments as single first-line therapy in digitalis poisoning. | Critical care medicine 20081101 |
Sensitive and specific LC-MS assay for quantification of digoxin in human plasma and urine. | Biomedical chromatography : BMC 20080701 |
Anti-HSV activity of digitoxin and its possible mechanisms. | Antiviral research 20080701 |
Infusion of albumin attenuates changes in serum protein binding of drugs in surgical patients compared with volume replacement with HAES. | Acta anaesthesiologica Scandinavica 20080301 |
Heart failure drug digitoxin induces calcium uptake into cells by forming transmembrane calcium channels. | Proceedings of the National Academy of Sciences of the United States of America 20080219 |
Digoxin treatment is associated with an increased incidence of breast cancer: a population-based case-control study. | Breast cancer research : BCR 20080101 |
Iatrogenic sick sinus syndrome. | American journal of critical care : an official publication, American Association of Critical-Care Nurses 20070501 |
De novo approach to 2-deoxy-beta-glycosides: asymmetric syntheses of digoxose and digitoxin. | The Journal of organic chemistry 20070330 |
Accumulation of O-GlcNAc-displaying CdTe quantum dots in cells in the presence of ATP. | Chembiochem : a European journal of chemical biology 20070305 |
Rhabdomyolysis after addition of digitoxin to chronic simvastatin and amiodarone therapy. | Drug metabolism and drug interactions 20070101 |
Role of p-glycoprotein inhibition for drug interactions: evidence from in vitro and pharmacoepidemiological studies. | Clinical pharmacokinetics 20070101 |
A stereoselective synthesis of digitoxin and digitoxigen mono- and bisdigitoxoside from digitoxigenin via a palladium-catalyzed glycosylation. | Organic letters 20060914 |
Digitoxin, at concentrations commonly found in the plasma of cardiac patients, antagonizes etoposide and idarubicin activity in K562 leukemia cells. | Leukemia research 20060701 |
Calcium-dependent regulation of NF-(kappa)B activation in cystic fibrosis airway epithelial cells. | Cellular signalling 20060501 |
[Cardiac failure in the geriatric patient]. | MMW Fortschritte der Medizin 20060323 |
Mechanisms of digoxin and digitoxin on the production of corticosterone in zona fasciculata-reticularis cells of ovariectomized rats. | Journal of cellular biochemistry 20060201 |
Nitric-oxide-dependent activation of pig oocytes: the role of the cGMP-signalling pathway. | Zygote (Cambridge, England) 20060201 |
Digitoxin inhibits the growth of cancer cell lines at concentrations commonly found in cardiac patients. | Journal of natural products 20051101 |
Neoglycorandomization and chemoenzymatic glycorandomization: two complementary tools for natural product diversification. | Journal of natural products 20051101 |
Inhibiting biosynthesis and/or metabolism of progestins in the ventral tegmental area attenuates lordosis of rats in behavioural oestrus. | Journal of neuroendocrinology 20050901 |
Repercussions of digoxin, digitoxin and estradiol on the endometrial histomorphometry of oophorectomized mice. | Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20050401 |
Bidirectional ventricular tachycardia due to digitalis intoxication. | Zeitschrift fur Kardiologie 20050201 |
A bitter tale. | The New England journal of medicine 20050106 |
Electrospray ionization mass spectrometry as a tool for determination of drug binding sites to human serum albumin by noncovalent interaction. | Rapid communications in mass spectrometry : RCM 20050101 |
Application of fluorescence correlation spectroscopy to hapten-antibody binding. | Methods in molecular biology (Clifton, N.J.) 20050101 |
A new selective population transfer experiment using a double pulsed field gradient spin-echo. | Magnetic resonance in chemistry : MRC 20041201 |
Inhibitory effects of digoxin and digitoxin on corticosterone production in rat zona fasciculata-reticularis cells. | British journal of pharmacology 20040801 |
Digitoxin mimics gene therapy with CFTR and suppresses hypersecretion of IL-8 from cystic fibrosis lung epithelial cells. | Proceedings of the National Academy of Sciences of the United States of America 20040518 |
A screen for drugs that protect against the cytotoxicity of polyglutamine-expanded androgen receptor. | Human molecular genetics 20040215 |
[Dementia induced by cardiokinetic and anti-hypertensive drugs]. | Nihon rinsho. Japanese journal of clinical medicine 20040101 |
Pharmaceutical-grade albumin: impaired drug-binding capacity in vitro. | BMC clinical pharmacology 20040101 |
Posterior encephalopathy with vasospasm: MRI and angiography. | Neuroradiology 20031201 |
Acaricidal effects of cardiac glycosides, azadirachtin and neem oil against the camel tick, Hyalomma dromedarii (Acari: Ixodidae). | Pest management science 20031101 |
Impact of left atrial size reduction on chronic atrial fibrillation in mitral valve surgery. | The Journal of heart valve disease 20030701 |
The Cuban experience in focusing pharmaceuticals policy to health population needs: initial results of the National Pharmacoepidemiology Network (1996-2001). | Pharmacoepidemiology and drug safety 20030101 |
Stereoselective synthesis of L-oliose trisaccharide via iterative alkynol cycloisomerization and acid-catalyzed glycosylation. | Organic letters 20021031 |
Bidirectional tachycardia: two cases and a review. | Anesthesia and analgesia 20020801 |
Three-dimensional quantitative structure-activity relationship analysis of ligand binding to human sequence antidigoxin monoclonal antibodies using comparative molecular field analysis. | Journal of medicinal chemistry 20020718 |
Immunoaffinity screening with capillary electrochromatography. | Electrophoresis 20020501 |
A neutrophil multitarget functional bioassay to detect anti-inflammatory natural products. | Journal of natural products 20020101 |
Progesterone attenuates the inhibitory effects of cardiotonic digitalis on pregnenolone production in rat luteal cells. | Journal of cellular biochemistry 20020101 |
Measurement of serum digitoxin in patients by radioimmunoassay using specific antiserum. | Clinica chimica acta; international journal of clinical chemistry 20011201 |
Inhibitory effects of digitalis on the proliferation of androgen dependent and independent prostate cancer cells. | The Journal of urology 20011101 |
Uremic sera contain inhibitors that block digitoxin-valproic acid interaction. | The American journal of the medical sciences 20011001 |
The reaction of digitoxin and digoxin with cyanoacetic acid hydrazide: synthesis of coumarin, thiazole, thiophene and pyridine derivatives with potential biological activities. | Archives of pharmacal research 20011001 |
[Augmentation of left ventricular outflow tract gradient by digitalis glycosides in a case of cardiac (AL-) amyloidosis]. | Deutsche medizinische Wochenschrift (1946) 20010817 |
Adverse drug reaction monitoring--digitoxin overdosage in the elderly. | International journal of clinical pharmacology and therapeutics 20010801 |
Cytotoxicity of digitoxin and related cardiac glycosides in human tumor cells. | Anti-cancer drugs 20010601 |
Direct inhibitory effect of digitalis on progesterone release from rat granulosa cells. | British journal of pharmacology 20010401 |
P-glycoprotein-mediated transport of digitoxin, alpha-methyldigoxin and beta-acetyldigoxin. | Naunyn-Schmiedeberg's archives of pharmacology 20010301 |
Treatment of congestive heart failure--current status of use of digitoxin. | European journal of clinical investigation 20010101 |
Digitoxin medication and cancer; case control and internal dose-response studies. | BMC cancer 20010101 |
Hepatorenal syndrome in cirrhotic patients: terlipressine is a safe and efficient treatment; propranolol and digitalic treatments: precipitating and preventing factors? | The American journal of gastroenterology 20001001 |
Chronic hypertension induced by ouabain but not digoxin in the rat: antihypertensive effect of digoxin and digitoxin. | Hypertension research : official journal of the Japanese Society of Hypertension 20000901 |
Atrial flutter with 1:1 conduction after administration of the antimalarial drug mefloquine. | Clinical cardiology 19961201 |
Prospective, randomized, placebo-controlled, double-blind testing of colour vision and electroretinogram at therapeutic and subtherapeutic digitoxin serum levels. | Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde 19940101 |
Synthesis of 20-hydroxy-, 20-amino-, and 20-nitro-14-hydroxy-21-nor-5 beta,14 beta-pregnane C-3 glycosides and related derivatives: structure-activity relationships of pregnanes that bind to the digitalis receptor. | Journal of medicinal chemistry 19930108 |
[Digitoxin-induced thrombocytopenia]. | Wiener klinische Wochenschrift 19930101 |
Treatment of a patient with severe digitoxin intoxication by Fab fragments of anti-digitalis antibodies. | Intensive care medicine 19920101 |
Effects of antiarrhythmic drugs on canine ventricular arrhythmia models: which electrophysiological characteristics of drugs are related to their effectiveness? | Cardiovascular drugs and therapy 19910801 |
Effect of digitoxin on cardiac arrhythmias in hemodialysis patients. | Klinische Wochenschrift 19871116 |
Quinidine syncope in children. | Journal of the American College of Cardiology 19870501 |
[Pharmacologic study of a semisynthetic digitalis derivative lacking the hydroxyl group on position 14 of the steroid nucleus]. | Archivos del Instituto de Cardiologia de Mexico 19860101 |
Effect of long-term administration of digoxin on exercise performance in chronic airflow obstruction. | European journal of respiratory diseases 19850401 |
Study of the factors influencing cardiac growth. II. Digitoxin treatment and isoproterenol-induced cardiac hypertrophy in the rat. | Acta biologica Hungarica 19850101 |
[Color perception disorders in therapeutic glycoside serum concentrations]. | Fortschritte der Medizin 19831117 |
[Digitoxin poisoning: reversing ventricular fibrillation with Fab fragments of anti-digoxin antibody]. | La Nouvelle presse medicale 19821225 |
Effect of age, clonidine or propranolol on behavioral toxicity induced with digitoxin in mice. | Pharmacology, biochemistry, and behavior 19820901 |
Reversal of digitalis-induced mesenteric vasospasm by sodium nitroprusside. | Archives of internal medicine 19820201 |
Effects of atropine on the cardiac arrest induced by propranolol and digitoxin in dogs. | Journal of electrocardiology 19820101 |
[Ocular side effects of digitalis (author's transl)]. | Klinische Monatsblatter fur Augenheilkunde 19810501 |
Digitalis delirium: a reminder. | Southern medical journal 19800301 |
Digitalis delirium: report of two cases. | The American journal of psychiatry 19780101 |
Reversal of advanced digitoxin toxicity and modification of pharmacokinetics by specific antibodies and Fab fragments. | The Journal of clinical investigation 19771201 |
[Magnesium--an alternative in treatment resistant tachyarrhythmias]. | Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 19770530 |
Hypotensive and antiarrhythmic effects of a new alkaloid, the 13-hydroxylupanine-2-pyrrolcarbonic acid ester, from the Madagascan plant Cadia ellisiana. | Arzneimittel-Forschung 19760101 |
Transient global amnesia associated with cardiac arrhythmia and digitalis intoxication. | Stroke 19750101 |
Effect of microsomal enzyme inducers on the biliary excretion of cardiac glycosides. | The Journal of pharmacology and experimental therapeutics 19741101 |
His bundle electrocardiography during bidirectional tachycardia. | Circulation 19730701 |
The clinical value of serum digitalis glycoside concentrations in the evaluation of drug toxicity. | Annals of the New York Academy of Sciences 19710706 |
Protection by spironolactone and oxandrolone against chronic digitoxin or indomethacin intoxication. | Toxicology and applied pharmacology 19710301 |
Possible mechanism of the prevention of digitoxin toxicity by spironolactone in the mouse. | Archives internationales de pharmacodynamie et de therapie 19710101 |
[Spironolactone protection against experimental cardiopathy due to digitoxin, disodium phosphate and oil]. | Pathologie-biologie 19700201 |
[Acute digitalic poisoning]. | Les Cahiers de medecine 19700201 |
Digitoxin induced cardiac necrosis and its inhibition. | Cardiologia 19690101 |
Atrial dissociation due to digitalis toxicity. | Angiology 19680601 |
[On the treatment of the digitalis-induced atrial tachycardia with AV conduction disorder. Experiences with sodium-magnesium aspartate]. | Medizinische Klinik 19680329 |
Influence of drugs, implanted into the hypothalamus, on the water consumption of rats. | The Journal of pharmacology and experimental therapeutics 19680101 |
[Cardiac arrhythmia in old age caused by digitalis intoxication]. | Nordisk medicin 19670427 |