Home Halogens Dibromoacetic acid

Dibromoacetic acid

CAS No.:
631-64-1
Catalog Number:
AG003PC2
Molecular Formula:
Molecular Weight:
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Product Description
Catalog Number:
AG003PC2
Chemical Name:
Dibromoacetic acid
CAS Number:
631-64-1
MDL Number:
MFCD00004205
IUPAC Name:
2,2-dibromoacetic acid
InChI:
InChI=1S/C2H2Br2O2/c3-1(4)2(5)6/h1H,(H,5,6)
InChI Key:
SIEILFNCEFEENQ-UHFFFAOYSA-N
EC Number:
211-165-5
UNII:
7FUW62YY5L
Properties
Complexity:
60.6  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
217.84g/mol
Formal Charge:
0
Heavy Atom Count:
6  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
217.844g/mol
Monoisotopic Mass:
215.842g/mol
Rotatable Bond Count:
1  
Topological Polar Surface Area:
37.3A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
1.5  
Literature
Title Journal
Dibromoacetic acid induced Cl.Ly1+2/-9 T-cell apoptosis and activation of MAPKs signaling cascades. Toxicology in vitro : an international journal published in association with BIBRA 20180301
Disinfection by-products in ballast water treatment: an evaluation of regulatory data. Water research 20121015
Exposure levels to brominated compounds in seawater swimming pools treated with chlorine. Water research 20120301
Associations between testicular hormones at adolescence and attendance at chlorinated swimming pools during childhood. International journal of andrology 20111001
Prospective power calculations for the Four Lab study of a multigenerational reproductive/developmental toxicity rodent bioassay using a complex mixture of disinfection by-products in the low-response region. International journal of environmental research and public health 20111001
Role of cytochrome P450c17α in dibromoacetic acid-induced testicular toxicity in rats. Archives of toxicology 20110501
Formation and modeling of disinfection by-products in drinking water of six cities in China. Journal of environmental monitoring : JEM 20110501
Simultaneous degradation of disinfection byproducts and earthy-musty odorants by the UV/H2O2 advanced oxidation process. Water research 20110401
Pregnancy loss and eye malformations in offspring of F344 rats following gestational exposure to mixtures of regulated trihalomethanes and haloacetic acids. Reproductive toxicology (Elmsford, N.Y.) 20110101
Atrazine-induced apoptosis of splenocytes in BALB/C mice. BMC medicine 20110101
Polymorphisms in GSTT1, GSTZ1, and CYP2E1, disinfection by-products, and risk of bladder cancer in Spain. Environmental health perspectives 20101101
[Formation and changes of regulated trihalomethanes and haloacetic acids in raw water of Yangtze River, Huangpu River and different treatment processes and pipelines network]. Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] 20101001
Physiologically based pharmacokinetic modeling of dibromoacetic acid in F344 rats. Toxicology and applied pharmacology 20100415
[Determination of trihalomethanes and haloacetic acids in the sample holding time, and their stability in the extract]. Wei sheng yan jiu = Journal of hygiene research 20100301
Mammalian cell cytotoxicity and genotoxicity of the haloacetic acids, a major class of drinking water disinfection by-products. Environmental and molecular mutagenesis 20100101
The assessment of population exposure to chlorination by-products: a study on the influence of the water distribution system. Environmental health : a global access science source 20100101
Immunotoxicity of dibromoacetic acid administered via drinking water to female B₆C₃F₁ mice. Journal of immunotoxicology 20100101
Development of a less toxic dichloroacetate analogue by docking and descriptor analysis. Bioinformation 20100101
A structural study of the interaction between the Dr haemagglutinin DraE and derivatives of chloramphenicol. Acta crystallographica. Section D, Biological crystallography 20090601
Biodegradation of haloacetic acids by bacterial isolates and enrichment cultures from drinking water systems. Environmental science & technology 20090501
Determination of ten haloacetic acids in drinking water using high-performance and ultra-performance liquid chromatography-tandem mass spectrometry. Journal of chromatographic science 20090101
Removal of haloacetic acids by nanofiltration. Journal of environmental sciences (China) 20090101
Simultaneous liquid-liquid microextraction/methylation for the determination of haloacetic acids in drinking waters by headspace gas chromatography. Journal of chromatography. A 20081031
Subacute oral exposure to dibromoacetic acid induced immunotoxicity and apoptosis in the spleen and thymus of the mice. Toxicological sciences : an official journal of the Society of Toxicology 20081001
Halogenated derivatives QSAR model using spectral moments to predict haloacetic acids (HAA) mutagenicity. Bioorganic & medicinal chemistry 20080515
Haloacetic acid and trihalomethane formation from the chlorination and bromination of aliphatic beta-dicarbonyl acid model compounds. Environmental science & technology 20080501
Impact of environmental pollutants on the male: effects on germ cell differentiation. Animal reproduction science 20080401
The formation and distribution of haloacetic acids in copper pipe during chlorination. Journal of hazardous materials 20080321
[Determination of five halogenated acetic acids in water using ion chromatography]. Se pu = Chinese journal of chromatography 20080101
Abstracts of papers presented at the 2008 pittsburgh conference. Journal of automated methods & management in chemistry 20080101
The healthy men study: an evaluation of exposure to disinfection by-products in tap water and sperm quality. Environmental health perspectives 20070801
Moderating influence of the drinking water disinfection by-product dibromoacetic acid on a dithiocarbamate-induced suppression of the luteinizing hormone surge in female rats. Reproductive toxicology (Elmsford, N.Y.) 20070601
Toxicology and carcinogenesis studies of dibromoacetic acid (Cas No. 631-64-1) in F344/N rats and B6C3F1 mice (drinking water studies). National Toxicology Program technical report series 20070401
Toxicity and carcinogenicity of the water disinfection byproduct, dibromoacetic acid, in rats and mice. Toxicology 20070212
Reductive dehalogenation of haloacetic acids by hemoglobin-loaded carbon nanotube electrode. Water research 20070101
Chronic exposure to low levels of dibromoacetic acid, a water disinfection by-product, adversely affects reproductive function in male rabbits. Journal of andrology 20070101
Determination of haloacetic acids in hospital effluent after chlorination by ion chromatography. Journal of environmental sciences (China) 20070101
Occurrence, genotoxicity, and carcinogenicity of regulated and emerging disinfection by-products in drinking water: a review and roadmap for research. Mutation research 20070101
Abstracts of papers presented at the 2007 pittsburgh conference. Journal of automated methods & management in chemistry 20070101
Synthesis, characterization, and in vitro antitumor properties of tris(hydroxymethyl)phosphine copper(I) complexes containing the new bis(1,2,4-triazol-1-yl)acetate ligand. Journal of medicinal chemistry 20061214
Short-term exposures to dihaloacetic acids produce dysmorphogenesis in mouse conceptuses in vitro. Reproductive toxicology (Elmsford, N.Y.) 20061001
[Impact of catalytic ozonation with ferric hydroxide on HAAs formation potential of a filtered surface water]. Huan jing ke xue= Huanjing kexue 20060801
[Determination of trace haloacetic acids in drinking water using ion chromatography coupled with solid phase extraction]. Se pu = Chinese journal of chromatography 20060501
Dibromoacetic acid, a commonly occurring water disinfection by-product, does not affect follicular populations in neonatal rats. Journal of toxicology and environmental health. Part A 20060301
Direct reaction of dibromoacetic acid with aldehydes promoted by samarium diiodide: an easy, efficient, and rapid synthesis of (E)-alpha,beta-unsaturated carboxylic acids with total stereoselectivity. The Journal of organic chemistry 20060217
Sub-chronic exposure to dibromoacetic acid, a water disinfection by-product, does not affect gametogenic potential in mice. Toxicological sciences : an official journal of the Society of Toxicology 20060101
Late pregnancy exposures to disinfection by-products and growth-related birth outcomes. Environmental health perspectives 20051201
DNA hypomethylation induced by drinking water disinfection by-products in mouse and rat kidney. Toxicological sciences : an official journal of the Society of Toxicology 20051001
The determination and fate of disinfection by-products from ozonation of polluted raw water. The Science of the total environment 20050601
Evaluation of the effects of various gas chromatographic parameters on haloacetic acids disinfection by-products analysis. Journal of chromatography. A 20050527
The effect of boiling water on disinfection by-product exposure. Water research 20050301
Density changes accompanying wave propagation in the cerium-catalyzed Belousov-Zhabotinsky reaction. The journal of physical chemistry. A 20050224
Twenty-week exposures to the drinking water disinfection by-product dibromoacetic acid: reproductive cyclicity and steroid concentrations in the female Sprague-Dawley rat. Reproductive toxicology (Elmsford, N.Y.) 20050101
Modulation of MAA-induced apoptosis in male germ cells: role of Sertoli cell P/Q-type calcium channels. Reproductive biology and endocrinology : RB&E 20050101
Kinetics of haloacetic acid reactions with Fe(0). Environmental science & technology 20041215
Developmental toxicity of mixtures: the water disinfection by-products dichloro-, dibromo- and bromochloro acetic acid in rat embryo culture. Reproductive toxicology (Elmsford, N.Y.) 20041101
Effect of dibromoacetic acid on DNA methylation, glycogen accumulation, and peroxisome proliferation in mouse and rat liver. Toxicological sciences : an official journal of the Society of Toxicology 20041101
Continuous exposure to dibromoacetic acid delays pubertal development and compromises sperm quality in the rat. Toxicological sciences : an official journal of the Society of Toxicology 20041001
Haloacid induced alterations in fertility and the sperm biomarker SP22 in the rat are additive: validation of an ELISA. Toxicological sciences : an official journal of the Society of Toxicology 20041001
Direct detection of trace haloacetates in drinking water using microbore ion chromatography. Improved detector sensitivity using a hydroxide gradient and a monolithic ion-exchange type suppressor. Journal of chromatography. A 20040827
Chronic exposure to dibromoacetic acid, a water disinfection byproduct, diminishes primordial follicle populations in the rabbit. Toxicological sciences : an official journal of the Society of Toxicology 20040701
Evaluation of the effects of water disinfection by-products, bromochloroacetic and dibromoacetic acids, on frog embryogenesis. Journal of toxicology and environmental health. Part A 20040625
Induction of peroxisome proliferation in cultured hepatocytes by a series of halogenated acetates. Toxicology 20040503
Neurotoxicity produced by dibromoacetic acid in drinking water of rats. Toxicological sciences : an official journal of the Society of Toxicology 20040501
[Investigation of bromate, haloacetic acids and perchlorate in Beijing's drinking water]. Huan jing ke xue= Huanjing kexue 20040301
Effect of NOM characteristics on brominated organics formation by ozonation. Environment international 20040201
DBP levels in chlorinated drinking water: effect of humic substances. Environmental monitoring and assessment 20040101
Tribromopyrrole, brominated acids, and other disinfection byproducts produced by disinfection of drinking water rich in bromide. Environmental science & technology 20030901
Dibromoacetic acid-induced elevations in circulating estradiol: effects in both cycling and ovariectomized/steroid-primed female rats. Reproductive toxicology (Elmsford, N.Y.) 20030101
Evaluation of disinfection by-products formation during ozonation of bromide-containing groundwater. Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering 20030101
Bromochloroacetic acid exerts qualitative effects on rat sperm: implications for a novel biomarker. Toxicological sciences : an official journal of the Society of Toxicology 20020701
Alterations in ovarian follicular progesterone secretion by elevated exposures to the drinking water disinfection by-product dibromoacetic acid: examination of the potential site(s) of impact along the steroidogenic pathway. Toxicology 20020227
Analysis of the cytotoxicity and mutagenicity of drinking water disinfection by-products in Salmonella typhimurium. Teratogenesis, carcinogenesis, and mutagenesis 20020101
Oral (drinking water) two-generation reproductive toxicity study of dibromoacetic acid (DBA) in rats. International journal of toxicology 20020101
Mammalian cell cytotoxicity and genotoxicity analysis of drinking water disinfection by-products. Environmental and molecular mutagenesis 20020101
[Study on the genotoxicity of dibromoacetic acid in drinking water]. Wei sheng yan jiu = Journal of hygiene research 20010901
Haloacetates in fog and rain. Environmental science & technology 20010401
Differential effects of dihalogenated and trihalogenated acetates in the liver of B6C3F1 mice. Journal of applied toxicology : JAT 20010101
Dibromoacetic acid, a prevalent by-product of drinking water disinfection, compromises the synthesis of specific seminiferous tubule proteins following both in vivo and in vitro exposures. Journal of andrology 20010101
Biodisposition of dibromoacetic acid (DBA) and bromodichloromethane (BDCM) administered to rats and rabbits in drinking water during range-finding reproduction and developmental toxicity studies. International journal of toxicology 20010101
Use of structure-activity relationships for probing biochemical mechanisms: glutathione transferase zeta conjugation of haloacids. Advances in experimental medicine and biology 20010101
Growth stimulation of a rat pituitary cell line MtT/E-2 by environmental estrogens in vitro and in vivo. Endocrine journal 19990801
Properties