Home Carboxys Coumarin-3-carboxylic acid

Coumarin-3-carboxylic acid

CAS No.:
531-81-7
Catalog Number:
AG003P2Q
Molecular Formula:
C10H6O4
Molecular Weight:
190.1522
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1g
98%
In Stock USA
United States
$13
- +
5g
98%
In Stock USA
United States
$19
- +
25g
98%
In Stock USA
United States
$50
- +
100g
98%
In Stock USA
United States
$150
- +
500g
98%
In Stock USA
United States
$600
- +
Product Description
Catalog Number:
AG003P2Q
Chemical Name:
Coumarin-3-carboxylic acid
CAS Number:
531-81-7
Molecular Formula:
C10H6O4
Molecular Weight:
190.1522
MDL Number:
MFCD00006852
IUPAC Name:
2-oxochromene-3-carboxylic acid
InChI:
InChI=1S/C10H6O4/c11-9(12)7-5-6-3-1-2-4-8(6)14-10(7)13/h1-5H,(H,11,12)
InChI Key:
ACMLKANOGIVEPB-UHFFFAOYSA-N
SMILES:
OC(=O)c1cc2ccccc2oc1=O
EC Number:
208-518-0
UNII:
V85UOV8788
Properties
Complexity:
305  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
190.027g/mol
Formal Charge:
0
Heavy Atom Count:
14  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
190.154g/mol
Monoisotopic Mass:
190.027g/mol
Rotatable Bond Count:
1  
Topological Polar Surface Area:
63.6A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
2.2  
Literature
Title Journal
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Synthesis and biological evaluation of coumarin derivatives as inhibitors of Mycobacterium bovis (BCG). Chemical biology & drug design 20121201
A novel luminescent terbium-3-carboxycoumarin probe for time-resolved fluorescence sensing of pesticides methomyl, aldicarb and prometryne. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20121101
Synthesis and antibacterial activities of novel 4-hydroxy-7-hydroxy- and 3-carboxycoumarin derivatives. Molecules (Basel, Switzerland) 20120910
Coumarin-3-carboxylic acid derivatives as potentiators and inhibitors of recombinant and native N-methyl-D-aspartate receptors. Neurochemistry international 20120901
Vanadium bromoperoxidase-coupled fluorescent assay for flow cytometry sorting of glucose oxidase gene libraries in double emulsions. Analytical and bioanalytical chemistry 20120901
Mechanism of radiation-induced reactions in aqueous solution of coumarin-3-carboxylic acid: effects of concentration, gas and additive on fluorescent product yield. Free radical research 20120701
Fluorescence and electrochemical sensing of pesticides methomyl, aldicarb and prometryne by the luminescent europium-3-carboxycoumarin probe. Journal of fluorescence 20120301
Chemical enhancement by nanomaterials under X-ray irradiation. Journal of the American Chemical Society 20120201
TiO2 nanoparticles are phototoxic to marine phytoplankton. PloS one 20120101
Molecular structure and spectroscopic studies on novel complexes of coumarin-3-carboxylic acid with Ni(II), Co(II), Zn(II) and Mn(II) ions based on density functional theory. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20111215
Diaqua-bis-(2-oxo-2H-chromene-3-carboxyl-ato-κO,O)manganese(II). Acta crystallographica. Section E, Structure reports online 20110601
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Diaqua-bis-(2-oxo-2H-chromene-3-carboxyl-ato)zinc(II). Acta crystallographica. Section E, Structure reports online 20110101
Hydroxyl radical and its scavengers in health and disease. Oxidative medicine and cellular longevity 20110101
Structural and functional characterization of a promiscuous feruloyl esterase (Est1E) from the rumen bacterium Butyrivibrio proteoclasticus. Proteins 20100501
Deciphering the mechanism of carbonic anhydrase inhibition with coumarins and thiocoumarins. Journal of medicinal chemistry 20100114
Cinnamyl 2-oxo-2H-chromene-3-carboxyl-ate. Acta crystallographica. Section E, Structure reports online 20091201
Menthyl 2-oxo-2H-chromene-3-carboxyl-ate. Acta crystallographica. Section E, Structure reports online 20091001
Peculiarities of the antioxidant and radioprotective effects of hydrated C60 fullerene nanostuctures in vitro and in vivo. Free radical biology & medicine 20090915
Trans-cinnamic acid and coumarin-3-carboxylic acid: experimental charge-density studies to shed light on [2 + 2] cycloaddition reactions. Acta crystallographica. Section B, Structural science 20090401
Efficient shRNA delivery into B and T lymphoma cells using lentiviral vector-mediated transfer. Journal of hematopathology 20090301
Synergistic effects of metal ion and the pre-senile cataract-causing G98R alphaA-crystallin: self-aggregation propensities and chaperone activity. Molecular vision 20090101
6-Substituted 2-oxo-2H-1-benzopyran-3-carboxylic acid derivatives in a new approach of the treatment of cancer cell invasion and metastasis. European journal of medicinal chemistry 20081201
Synthesis and application of molecular probe for detection of hydroxyl radicals produced by Na(125)I and gamma-rays in aqueous solution. International journal of radiation biology 20081201
Effect of amino acids on X-ray-induced hydrogen peroxide and hydroxyl radical formation in water and 8-oxoguanine in DNA. Biochemistry. Biokhimiia 20080401
Six naphthylisoquinoline alkaloids and a related benzopyranone from a Congolese Ancistrocladus species related to Ancistrocladus congolensis. Phytochemistry 20080201
[Formation of hydrogen peroxide and hydroxyl radicals in aqueous solutions of L-amino acids by the action of X-rays and heat]. Biofizika 20080101
Anticancer Activity of Ag(I) N-Heterocyclic Carbene Complexes Derived from 4,5-Dichloro-1H-Imidazole. Metal-based drugs 20080101
Theoretical study of metal-ligand interaction in Sm(III), Eu(III), and Tb(III) complexes of coumarin-3-carboxylic acid in the gas phase and solution. Inorganic chemistry 20071210
Near infrared multiphoton-induced generation and detection of hydroxyl radicals in a biochemical system. Archives of biochemistry and biophysics 20070815
Asymmetric total synthesis of (-)-Linderol A. The Journal of organic chemistry 20070720
A study of the role of apoptotic cell death and cell cycle events mediating the mechanism of action of 6-hydroxycoumarin-3-carboxylatosilver in human malignant hepatic cells. Cancer letters 20070518
In vitro anti-tumour and cyto-selective effects of coumarin-3-carboxylic acid and three of its hydroxylated derivatives, along with their silver-based complexes, using human epithelial carcinoma cell lines. Cancer letters 20070418
Biological activity of 3-formylchromones and related compounds. In vivo (Athens, Greece) 20070101
New Samarium(III), Gadolinium(III), and Dysprosium(III) Complexes of Coumarin-3-Carboxylic Acid as Antiproliferative Agents. Metal-based drugs 20070101
Microsphere-based protease assays and screening application for lethal factor and factor Xa. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Guanosine and inosine display antioxidant activity, protect DNA in vitro from oxidative damage induced by reactive oxygen species, and serve as radioprotectors in mice. Radiation research 20060501
Diels-Alder reactions of 3-substituted coumarins in water and under high-pressure condition. An uncatalyzed route to tetrahydro-6H-benzo[c]chromen-6-ones. The Journal of organic chemistry 20060106
(Sub)-picosecond spectral evolution of fluorescence in photoactive proteins studied with a synchroscan streak camera system. Photochemistry and photobiology 20060101
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[Guanosine and inosine as natural geneprotectors for mice blood cells exposed to X-rays]. Radiatsionnaia biologiia, radioecologiia 20060101
Effects of iron on Vitamin C/copper-induced hydroxyl radical generation in bicarbonate-rich water. Free radical research 20050501
Inhibition of monoamine oxidases by coumarin-3-acyl derivatives: biological activity and computational study. Bioorganic & medicinal chemistry letters 20040716
Glucuronidation of carboxylic acid containing compounds by UDP-glucuronosyltransferase isoforms. Archives of biochemistry and biophysics 20040415
Fungal modification of the hydroxyl radical detector coumarin-3-carboxylic acid. FEMS microbiology ecology 20031101
2-Amino-1,3-benzothiazole-ethyl coumarin-3-carboxylate (1/1). Acta crystallographica. Section C, Crystal structure communications 20031001
Formylchromone derivatives as a novel class of protein tyrosine phosphatase 1B inhibitors. Bioorganic & medicinal chemistry letters 20030804
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Measurement of ascorbic acid (vitamin C) induced hydroxyl radical generation in household drinking water. Free radical research 20021201
Detection of hydroxyl radicals produced by wood-decomposing fungi. FEMS microbiology ecology 20020401
[Generation of hydroxyl radicals and other redox active compounds in the sea water exposed to heat]. Biofizika 20020101
Generation of hydroxyl radicals by the antiviral compound phosphonoformic acid (foscarnet). Pharmacology & toxicology 20010701
Synthesis and characterization of a binuclear coumarin-3-carboxylate copper(II) complex. Journal of inorganic biochemistry 20010301
Properties