Home Other Building Blocks Chorismic acid from Enterobacter aerogenes

Chorismic acid from Enterobacter aerogenes

CAS No.:
617-12-9
Catalog Number:
AG003OVQ
Molecular Formula:
Molecular Weight:
Pack Size
Purity
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Product Description
Catalog Number:
AG003OVQ
Chemical Name:
Chorismic acid from Enterobacter aerogenes
CAS Number:
617-12-9
MDL Number:
MFCD00135935
IUPAC Name:
(3R,4R)-3-(1-carboxyethenoxy)-4-hydroxycyclohexa-1,5-diene-1-carboxylic acid
InChI:
InChI=1S/C10H10O6/c1-5(9(12)13)16-8-4-6(10(14)15)2-3-7(8)11/h2-4,7-8,11H,1H2,(H,12,13)(H,14,15)/t7-,8-/m1/s1
InChI Key:
WTFXTQVDAKGDEY-HTQZYQBOSA-N
UNII:
GI1BLY82Y1
Properties
Complexity:
392  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
2  
Defined Bond Stereocenter Count:
0
Exact Mass:
226.048g/mol
Formal Charge:
0
Heavy Atom Count:
16  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
3  
Isotope Atom Count:
0
Molecular Weight:
226.184g/mol
Monoisotopic Mass:
226.048g/mol
Rotatable Bond Count:
4  
Topological Polar Surface Area:
104A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
0.2  
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Effective and specific in planta RNAi in cyst nematodes: expression interference of four parasitism genes reduces parasitic success. Journal of experimental botany 20090101
Characterization of a key trifunctional enzyme for aromatic amino acid biosynthesis in Archaeoglobus fulgidus. Extremophiles : life under extreme conditions 20090101
Coordinations between gene modules control the operation of plant amino acid metabolic networks. BMC systems biology 20090101
Sequence mining and transcript profiling to explore cyst nematode parasitism. BMC genomics 20090101
The Staphylococcus aureus response to unsaturated long chain free fatty acids: survival mechanisms and virulence implications. PloS one 20090101
Diverse protein regulations on PHA formation in Ralstonia eutropha on short chain organic acids. International journal of biological sciences 20090101
Uncovering metabolic pathways relevant to phenotypic traits of microbial genomes. Genome biology 20090101
Population-specific gene expression in the plant pathogenic nematode Heterodera glycines exists prior to infection and during the onset of a resistant or susceptible reaction in the roots of the Glycine max genotype Peking. BMC genomics 20090101
Snapshot of iron response in Shewanella oneidensis by gene network reconstruction. BMC genomics 20090101
Metabolic engineering for improving anthranilate synthesis from glucose in Escherichia coli. Microbial cell factories 20090101
Water deficit alters differentially metabolic pathways affecting important flavor and quality traits in grape berries of Cabernet Sauvignon and Chardonnay. BMC genomics 20090101
The genome sequence of Geobacter metallireducens: features of metabolism, physiology and regulation common and dissimilar to Geobacter sulfurreducens. BMC microbiology 20090101
Heme and menaquinone induced electron transport in lactic acid bacteria. Microbial cell factories 20090101
Deciphering the connectivity structure of biological networks using MixNet. BMC bioinformatics 20090101
A single transcription factor regulates evolutionarily diverse but functionally linked metabolic pathways in response to nutrient availability. Molecular systems biology 20090101
The complete genome of Teredinibacter turnerae T7901: an intracellular endosymbiont of marine wood-boring bivalves (shipworms). PloS one 20090101
A comparative genomics approach to understanding the biosynthesis of the sunscreen scytonemin in cyanobacteria. BMC genomics 20090101
Grapevine cell early activation of specific responses to DIMEB, a resveratrol elicitor. BMC genomics 20090101
Time-resolved transcriptome analysis of Bacillus subtilis responding to valine, glutamate, and glutamine. PloS one 20090101
2-DE analysis indicates that Acinetobacter baumannii displays a robust and versatile metabolism. Proteome science 20090101
Genome sequence of the versatile fish pathogen Edwardsiella tarda provides insights into its adaptation to broad host ranges and intracellular niches. PloS one 20090101
The transcriptome of the nosocomial pathogen Enterococcus faecalis V583 reveals adaptive responses to growth in blood. PloS one 20090101
Network analysis of the transcriptional pattern of young and old cells of Escherichia coli during lag phase. BMC systems biology 20090101
The transcriptional programme of Salmonella enterica serovar Typhimurium reveals a key role for tryptophan metabolism in biofilms. BMC genomics 20090101
Functional analysis of aromatic biosynthetic pathways in Pseudomonas putida KT2440. Microbial biotechnology 20090101
Relative tolerance of an enzymatic molten globule and its thermostable counterpart to point mutation. Biochemistry 20081223
PhzA/B catalyzes the formation of the tricycle in phenazine biosynthesis. Journal of the American Chemical Society 20081217
Engineered native pathways for high kaempferol and caffeoylquinate production in potato. Plant biotechnology journal 20081201
Alternative splicing: a novel mechanism of regulation identified in the chorismate mutase gene of the potato cyst nematode Globodera rostochiensis. Molecular and biochemical parasitology 20081101
Kinetics and thermodynamics of ligand binding to a molten globular enzyme and its native counterpart. Journal of molecular biology 20081017
Directing the evolution of Rubisco and Rubisco activase: first impressions of a new tool for photosynthesis research. Photosynthesis research 20081001
Comprehensive transcriptome analysis of phytohormone biosynthesis and signaling genes in microspore/pollen and tapetum of rice. Plant & cell physiology 20081001
A comparative biochemical and structural analysis of the intracellular chorismate mutase (Rv0948c) from Mycobacterium tuberculosis H(37)R(v) and the secreted chorismate mutase (y2828) from Yersinia pestis. The FEBS journal 20081001
Probing protein environment in an enzymatic process: All-electron quantum chemical analysis combined with ab initio quantum mechanical/molecular mechanical modeling of chorismate mutase. The Journal of chemical physics 20080928
An alternative menaquinone biosynthetic pathway operating in microorganisms. Science (New York, N.Y.) 20080919
Anthranilate synthase subunit organization in Chromobacterium violaceum. Genetics and molecular research : GMR 20080916
Structural studies of prephenate dehydratase from Mycobacterium tuberculosis H37Rv by SAXS, ultracentrifugation, and computational analysis. Proteins 20080901
CHARMMing: a new, flexible web portal for CHARMM. Journal of chemical information and modeling 20080901
Molecular modeling and dynamics studies of Shikimate Kinase from Bacillus anthracis. Bioorganic & medicinal chemistry 20080901
Biosynthesis of diazepinomicin/ECO-4601, a Micromonospora secondary metabolite with a novel ring system. Journal of natural products 20080901
Structural studies of shikimate 5-dehydrogenase from Mycobacterium tuberculosis. Proteins 20080801
A dynamic view of enzyme catalysis. Journal of molecular modeling 20080801
GCN2-dependent phosphorylation of eukaryotic translation initiation factor-2alpha in Arabidopsis. Journal of experimental botany 20080801
Allosteric communication in myosin V: from small conformational changes to large directed movements. PLoS computational biology 20080801
Formylglycinamide ribonucleotide amidotransferase from Thermotoga maritima: structural insights into complex formation. Biochemistry 20080729
Indole production by Pseudomonas stutzeri strain NAP-3 during anaerobic naphthalene biodegradation in the presence of dimethyl formamide. Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering 20080715
Characterization and biological function of the ISOCHORISMATE SYNTHASE2 gene of Arabidopsis. Plant physiology 20080701
Chemical and genetic validation of dihydrofolate reductase-thymidylate synthase as a drug target in African trypanosomes. Molecular microbiology 20080701
A computational framework to empower probabilistic protein design. Bioinformatics (Oxford, England) 20080701
(1RS,4SR)-3-Dichloro-methyl-ene-1,4-dimethyl-2-oxabicyclo-[2.2.2]oct-5-ene. Acta crystallographica. Section E, Structure reports online 20080701
Molecular dynamics simulation of the Escherichia coli NikR protein: equilibrium conformational fluctuations reveal interdomain allosteric communication pathways. Journal of molecular biology 20080516
Crystal structure of the pyocyanin biosynthetic protein PhzS. Biochemistry 20080513
Structure of isochorismate synthase in complex with magnesium. Acta crystallographica. Section D, Biological crystallography 20080501
Studies on a new biosynthetic pathway for menaquinone. Journal of the American Chemical Society 20080430
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Predicting an improvement of secondary catalytic activity of promiscuous isochorismate pyruvate lyase by computational design. Journal of the American Chemical Society 20080312
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Metabolic engineering of Escherichia coli to enhance phenylalanine production. Applied microbiology and biotechnology 20080201
CPSARST: an efficient circular permutation search tool applied to the detection of novel protein structural relationships. Genome biology 20080101
Quantitative 1H NMR metabolomics reveals extensive metabolic reprogramming of primary and secondary metabolism in elicitor-treated opium poppy cell cultures. BMC plant biology 20080101
Coutilization of glucose and glycerol enhances the production of aromatic compounds in an Escherichia coli strain lacking the phosphoenolpyruvate: carbohydrate phosphotransferase system. Microbial cell factories 20080101
The tryptophan pathway genes of the Sargasso Sea metagenome: new operon structures and the prevalence of non-operon organization. Genome biology 20080101
Use of the lambda Red recombinase system to rapidly generate mutants in Pseudomonas aeruginosa. BMC molecular biology 20080101
Reconstruction and analysis of the genetic and metabolic regulatory networks of the central metabolism of Bacillus subtilis. BMC systems biology 20080101
A complete collection of single-gene deletion mutants of Acinetobacter baylyi ADP1. Molecular systems biology 20080101
Alleviation of feedback inhibition in Saccharomyces cerevisiae aromatic amino acid biosynthesis: quantification of metabolic impact. Metabolic engineering 20080101
Metabolic pathways of the wheat (Triticum aestivum) endosperm amyloplast revealed by proteomics. BMC plant biology 20080101
Characterisation of the tryptophan synthase alpha subunit in maize. BMC plant biology 20080101
Evidence of a chimeric genome in the cyanobacterial ancestor of plastids. BMC evolutionary biology 20080101
The Mycobacterium tuberculosis Rv2540c DNA sequence encodes a bifunctional chorismate synthase. BMC biochemistry 20080101
The hidden universal distribution of amino acid biosynthetic networks: a genomic perspective on their origins and evolution. Genome biology 20080101
Evidence of recent interkingdom horizontal gene transfer between bacteria and Candida parapsilosis. BMC evolutionary biology 20080101
Expression of cell wall related genes in basal and ear internodes of silking brown-midrib-3, caffeic acid O-methyltransferase (COMT) down-regulated, and normal maize plants. BMC plant biology 20080101
An in silico analysis of T-box regulated genes and T-box evolution in prokaryotes, with emphasis on prediction of substrate specificity of transporters. BMC genomics 20080101
The transcriptional program underlying the physiology of clostridial sporulation. Genome biology 20080101
The fused TrpEG from Streptomyces venezuelae is an anthranilate synthase, not a 2-amino-2-deoxyisochorismate [corrected] (ADIC) synthase. Ethnicity & disease 20080101
Transcriptomic analysis of the exit from dormancy of Aspergillus fumigatus conidia. BMC genomics 20080101
Simplivariate models: ideas and first examples. PloS one 20080101
Organogenic nodule development in hop (Humulus lupulus L.): transcript and metabolic responses. BMC genomics 20080101
RNomics and Modomics in the halophilic archaea Haloferax volcanii: identification of RNA modification genes. BMC genomics 20080101
Linking gene regulation and the exo-metabolome: a comparative transcriptomics approach to identify genes that impact on the production of volatile aroma compounds in yeast. BMC genomics 20080101
Architecture of thermal adaptation in an Exiguobacterium sibiricum strain isolated from 3 million year old permafrost: a genome and transcriptome approach. BMC genomics 20080101
Comparative genomics of vesicomyid clam (Bivalvia: Mollusca) chemosynthetic symbionts. BMC genomics 20080101
Acidithiobacillus ferrooxidans metabolism: from genome sequence to industrial applications. BMC genomics 20080101
Structure and dynamics of a molten globular enzyme. Nature structural & molecular biology 20071201
Determination of the stereochemistry of 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate, a key intermediate in menaquinone biosynthesis. Organic letters 20071108
The isochorismate pathway is negatively regulated by salicylic acid signaling in O3-exposed Arabidopsis. Planta 20071001
A simple selection strategy for evolving highly efficient enzymes. Nature biotechnology 20071001
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Identification of genes differentially expressed during ripening of banana. Journal of plant physiology 20070801
Domain folding and flexibility of Escherichia coli FtsZ determined by tryptophan site-directed mutagenesis. Protein science : a publication of the Protein Society 20070801
Interfacing Q-Chem and CHARMM to perform QM/MM reaction path calculations. Journal of computational chemistry 20070715
Exploring SCC-DFTB paths for mapping QM/MM reaction mechanisms. The journal of physical chemistry. A 20070705
Exhaustive mutagenesis of six secondary active-site residues in Escherichia coli chorismate mutase shows the importance of hydrophobic side chains and a helix N-capping position for stability and catalysis. Biochemistry 20070612
Ligand based virtual screening and biological evaluation of inhibitors of chorismate mutase (Rv1885c) from Mycobacterium tuberculosis H37Rv. Bioorganic & medicinal chemistry letters 20070601
From scratch to value: engineering Escherichia coli wild type cells to the production of L-phenylalanine and other fine chemicals derived from chorismate. Applied microbiology and biotechnology 20070601
A transition path sampling study of the reaction catalyzed by the enzyme chorismate mutase. The journal of physical chemistry. B 20070524
Global analysis of community-associated methicillin-resistant Staphylococcus aureus exoproteins reveals molecules produced in vitro and during infection. Cellular microbiology 20070501
Nucleophile selectivity of chorismate-utilizing enzymes. Chembiochem : a European journal of chemical biology 20070416
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Investigation of the first shot phenomenon in MALDI mass spectrometry of protein complexes. The Analyst 20070301
Chorismate synthase: an attractive target for drug development against orphan diseases. Current drug targets 20070301
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Structural and functional analysis of the pyocyanin biosynthetic protein PhzM from Pseudomonas aeruginosa. Biochemistry 20070220
Relative tolerance of mesostable and thermostable protein homologs to extensive mutation. Proteins 20070201
Vitamin K1 accumulation in tobacco plants overexpressing bacterial genes involved in the biosynthesis of salicylic acid. Journal of biotechnology 20070130
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Structure and mechanism of MbtI, the salicylate synthase from Mycobacterium tuberculosis. Biochemistry 20070130
Computer-aided rational design of catalytic antibodies: The 1F7 case. Angewandte Chemie (International ed. in English) 20070101
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Effects of the magnesium and chloride ions and shikimate on the structure of shikimate kinase from Mycobacterium tuberculosis. Acta crystallographica. Section F, Structural biology and crystallization communications 20070101
Blockade of catecholamine-induced growth by adrenergic and dopaminergic receptor antagonists in Escherichia coli O157:H7, Salmonella enterica and Yersinia enterocolitica. BMC microbiology 20070101
Modelling the evolution of the archeal tryptophan synthase. BMC evolutionary biology 20070101
Toward the automated generation of genome-scale metabolic networks in the SEED. BMC bioinformatics 20070101
The crystal structure of Escherichia coli TdcF, a member of the highly conserved YjgF/YER057c/UK114 family. BMC structural biology 20070101
Comparative genomics of bacterial and plant folate synthesis and salvage: predictions and validations. BMC genomics 20070101
An 'Electronic Fluorescent Pictograph' browser for exploring and analyzing large-scale biological data sets. PloS one 20070101
GntR family of regulators in Mycobacterium smegmatis: a sequence and structure based characterization. BMC genomics 20070101
Metabolic transcription analysis of engineered Escherichia coli strains that overproduce L-phenylalanine. Microbial cell factories 20070101
Chemical accuracy in QM/MM calculations on enzyme-catalysed reactions. Chemistry Central journal 20070101
Developing a systems biology approach to study disease progression caused by Heterodera glycines in Glycine max. Gene regulation and systems biology 20070101
Redesigning the PheA domain of gramicidin synthetase leads to a new understanding of the enzyme's mechanism and selectivity. Biochemistry 20061226
Aminodeoxychorismate synthase inhibitors from one-bead one-compound combinatorial libraries: 'staged' inhibitor design. Journal of medicinal chemistry 20061214
Novel benzene ring biosynthesis from C(3) and C(4) primary metabolites by two enzymes. The Journal of biological chemistry 20061201
Calculation of smooth potential energy surfaces using local electron correlation methods. The Journal of chemical physics 20061114
Two crystal structures of the isochorismate pyruvate lyase from Pseudomonas aeruginosa. The Journal of biological chemistry 20061103
Biochemical and genetic characterization of an early step in a novel pathway for the biosynthesis of aromatic amino acids and p-aminobenzoic acid in the archaeon Methanococcus maripaludis. Molecular microbiology 20061101
High-accuracy computation of reaction barriers in enzymes. Angewandte Chemie (International ed. in English) 20061020
Purification and characterization of a functionally active Mycobacterium tuberculosis prephenate dehydrogenase. Protein expression and purification 20061001
Three-dimensional structure of iminodisuccinate epimerase defines the fold of the MmgE/PrpD protein family. Journal of molecular biology 20060922
Hybrid quantum mechanics/molecular mechanics simulations with two-dimensional interpolated corrections: application to enzymatic processes. The journal of physical chemistry. B 20060907
Gene expression of Escherichia coli in continuous culture during adaptation to artificial sunlight. Environmental microbiology 20060901
Temperature dependence of the structure of the substrate and active site of the Thermus thermophilus chorismate mutase E x S complex. Biochemistry 20060718
Determination of the crystal structure of EntA, a 2,3-dihydro-2,3-dihydroxybenzoic acid dehydrogenase from Escherichia coli. Acta crystallographica. Section D, Biological crystallography 20060701
The 2.15 A crystal structure of Mycobacterium tuberculosis chorismate mutase reveals an unexpected gene duplication and suggests a role in host-pathogen interactions. Biochemistry 20060613
Isolation and characterization of another cDNA encoding a chorismate mutase from the phytoparasitic nematode Meloidogyne arenaria. Experimental parasitology 20060601
Structural characterization of GntR/HutC family signaling domain. Protein science : a publication of the Protein Society 20060601
Metabolic complementarity and genomics of the dual bacterial symbiosis of sharpshooters. PLoS biology 20060601
Folate synthesis in plants: purification, kinetic properties, and inhibition of aminodeoxychorismate synthase. The Biochemical journal 20060515
Crystal structure of prephenate dehydrogenase from Aquifex aeolicus. Insights into the catalytic mechanism. The Journal of biological chemistry 20060505
Epidermis is a pivotal site of at least four secondary metabolic pathways in Catharanthus roseus aerial organs. Planta 20060501
Structure of chorismate synthase from Mycobacterium tuberculosis. Journal of structural biology 20060501
Preliminary X-ray crystallographic analysis of the secreted chorismate mutase from Mycobacterium tuberculosis: a tricky crystallization problem solved. Acta crystallographica. Section F, Structural biology and crystallization communications 20060501
The catalytic power of enzymes: conformational selection or transition state stabilization? FEBS letters 20060417
1.6 A crystal structure of the secreted chorismate mutase from Mycobacterium tuberculosis: novel fold topology revealed. Journal of molecular biology 20060414
Testing electrostatic complementarity in enzyme catalysis: hydrogen bonding in the ketosteroid isomerase oxyanion hole. PLoS biology 20060401
Crystal structures of Yersinia enterocolitica salicylate synthase and its complex with the reaction products salicylate and pyruvate. Journal of molecular biology 20060324
Crystallization and X-ray diffraction analysis of salicylate synthase, a chorismate-utilizing enyme involved in siderophore biosynthesis. Acta crystallographica. Section F, Structural biology and crystallization communications 20060301
Conversion of MapMan to allow the analysis of transcript data from Solanaceous species: effects of genetic and environmental alterations in energy metabolism in the leaf. Plant molecular biology 20060301
New insights into the evolutionary links relating to the 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase subfamilies. The Journal of biological chemistry 20060217
Experimental and computational investigation of the uncatalyzed rearrangement and elimination reactions of isochorismate. Journal of the American Chemical Society 20060215
The allosteric mechanism of yeast chorismate mutase: a dynamic analysis. Journal of molecular biology 20060210
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Structural analysis of ligand binding and catalysis in chorismate lyase. Archives of biochemistry and biophysics 20060101
An application of statistics to comparative metagenomics. BMC bioinformatics 20060101
Modeling methanogenesis with a genome-scale metabolic reconstruction of Methanosarcina barkeri. Molecular systems biology 20060101
In vivo 15N-enrichment of metabolites in suspension cultured cells and its application to metabolomics. Biotechnology progress 20060101
The complete chloroplast genome sequence of Citrus sinensis (L.) Osbeck var 'Ridge Pineapple': organization and phylogenetic relationships to other angiosperms. BMC plant biology 20060101
Transcriptome changes in the phenylpropanoid pathway of Glycine max in response to Pseudomonas syringae infection. BMC plant biology 20060101
PIRSF family classification system for protein functional and evolutionary analysis. Evolutionary bioinformatics online 20060101
p-Hydroxybenzoic acid synthesis in Mycobacterium tuberculosis. The Journal of biological chemistry 20051209
The structure of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase from Mycobacterium tuberculosis reveals a common catalytic scaffold and ancestry for type I and type II enzymes. Journal of molecular biology 20051209
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An active enzyme constructed from a 9-amino acid alphabet. The Journal of biological chemistry 20051111
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Characterization of a recombinant type II 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase from Helicobacter pylori. The Biochemical journal 20050815
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Simultaneous optimization of enzyme activity and quaternary structure by directed evolution. Protein science : a publication of the Protein Society 20050801
Mechanistic and inhibition studies of chorismate-utilizing enzymes. Biochemical Society transactions 20050801
Salicylic acid accumulation under O3 exposure is regulated by ethylene in tobacco plants. Plant & cell physiology 20050701
Shikimate and folate pathways in the protozoan parasite, Perkinsus olseni. Molecular and biochemical parasitology 20050701
Away from the edge II: in-house Se-SAS phasing with chromium radiation. Acta crystallographica. Section D, Biological crystallography 20050701
Design and synthesis of aromatic inhibitors of anthranilate synthase. Organic & biomolecular chemistry 20050621
Construction and characterization of Pichia pastoris strains for labeling aromatic amino acids in recombinant proteins. Protein expression and purification 20050601
Selection of Heterodera glycines chorismate mutase-1 alleles on nematode-resistant soybean. Molecular plant-microbe interactions : MPMI 20050601
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Inhibition studies on salicylate synthase. Organic & biomolecular chemistry 20050521
Purified recombinant hypothetical protein coded by open reading frame Rv1885c of Mycobacterium tuberculosis exhibits a monofunctional AroQ class of periplasmic chorismate mutase activity. The Journal of biological chemistry 20050520
Multiple-steering QM-MM calculation of the free energy profile in chorismate mutase. Journal of the American Chemical Society 20050518
Investigation of ligand binding and protein dynamics in Bacillus subtilis chorismate mutase by transverse relaxation optimized spectroscopy-nuclear magnetic resonance. Biochemistry 20050510
Biosynthesis of ribose-5-phosphate and erythrose-4-phosphate in archaea: a phylogenetic analysis of archaeal genomes. Archaea (Vancouver, B.C.) 20050501
Crystallization and preliminary X-ray crystallographic studies of Mycobacterium tuberculosis chorismate mutase. Acta crystallographica. Section F, Structural biology and crystallization communications 20050501
Exploring the diversity of complex metabolic networks. Bioinformatics (Oxford, England) 20050415
Computationally designed variants of Escherichia coli chorismate mutase show altered catalytic activity. Protein engineering, design & selection : PEDS 20050401
Regulation of the ubiquinone (coenzyme Q) biosynthetic genes ubiCA in Escherichia coli. Current microbiology 20050401
Computing kinetic isotope effects for chorismate mutase with high accuracy. A new DFT/MM strategy. The journal of physical chemistry. B 20050310
Structural classification of thioredoxin-like fold proteins. Proteins 20050201
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Characterization of the secreted chorismate mutase from the pathogen Mycobacterium tuberculosis. The FEBS journal 20050101
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[Bioconversion of phenyllactate to phenylalanine by bacteria of the genus Pseudomonas]. Prikladnaia biokhimiia i mikrobiologiia 20050101
The TyrA family of aromatic-pathway dehydrogenases in phylogenetic context. BMC biology 20050101
Functional annotation by identification of local surface similarities: a novel tool for structural genomics. BMC bioinformatics 20050101
Interaction preferences across protein-protein interfaces of obligatory and non-obligatory components are different. BMC structural biology 20050101
Crystallization and preliminary X-ray crystallographic analysis of MbtI, a protein essential for siderophore biosynthesis in Mycobacterium tuberculosis. Acta crystallographica. Section F, Structural biology and crystallization communications 20050101
Initial evaluation of sugarcane as a production platform for p-hydroxybenzoic acid. Plant biotechnology journal 20050101
Two chorismate mutase genes from the root-knot nematode Meloidogyne incognita. Molecular plant pathology 20050101
Integration of E. coli aroG-pheA tandem genes into Corynebacterium glutamicum tyrA locus and its effect on L-phenylalanine biosynthesis. World journal of gastroenterology 20041215
Differential transition-state stabilization in enzyme catalysis: quantum chemical analysis of interactions in the chorismate mutase reaction and prediction of the optimal catalytic field. Journal of the American Chemical Society 20041215
Metabolic engineering of the chloroplast genome using the Echerichia coli ubiC gene reveals that chorismate is a readily abundant plant precursor for p-hydroxybenzoic acid biosynthesis. Plant physiology 20041201
Crystallization and preliminary X-ray crystallographic analysis of chorismate synthase from Mycobacterium tuberculosis. Acta crystallographica. Section D, Biological crystallography 20041101
Structure of the phenazine biosynthesis enzyme PhzG. Acta crystallographica. Section D, Biological crystallography 20041101
Structure and function of the phenazine biosynthesis protein PhzF from Pseudomonas fluorescens 2-79. Biochemistry 20041005
The Arabidopsis phenylalanine insensitive growth mutant exhibits a deregulated amino acid metabolism. Plant physiology 20041001
Design, synthesis, and evaluation of aza inhibitors of chorismate mutase. Bioorganic & medicinal chemistry 20040915
Identification of 4-amino-4-deoxychorismate synthase as the molecular target for the antimicrobial action of (6s)-6-fluoroshikimate. Journal of the American Chemical Society 20040818
Para-position derivatives of fungal anthelmintic cyclodepsipeptides engineered with Streptomyces venezuelae antibiotic biosynthetic genes. Nature biotechnology 20040701
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Deciphering enzymes. Genetic selection as a probe of structure and mechanism. European journal of biochemistry 20040501
Use of solid-phase subtractive hybridization for the identification of parasitism gene candidates from the root-knot nematode Meloidogyne incognita. Molecular plant pathology 20040501
Transition state stabilization and substrate strain in enzyme catalysis: ab initio QM/MM modelling of the chorismate mutase reaction. Organic & biomolecular chemistry 20040407
Nuclear import of yeast Gcn4p requires karyopherins Srp1p and Kap95p. Molecular genetics and genomics : MGG 20040401
Abyssomicins, inhibitors of the para-aminobenzoic acid pathway produced by the marine Verrucosispora strain AB-18-032. The Journal of antibiotics 20040401
Mechanism of chorismate synthase. Role of the two invariant histidine residues in the active site. The Journal of biological chemistry 20040305
Conservation of mechanism in three chorismate-utilizing enzymes. Journal of the American Chemical Society 20040303
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Crystal structure of chorismate synthase: a novel FMN-binding protein fold and functional insights. Journal of molecular biology 20040227
Theoretical insights in enzyme catalysis. Chemical Society reviews 20040220
Structure of the OmpA-like domain of RmpM from Neisseria meningitidis. Molecular microbiology 20040201
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Crystal structure of the bifunctional chorismate synthase from Saccharomyces cerevisiae. The Journal of biological chemistry 20040102
The purification, crystallization and preliminary structural characterization of PhzF, a key enzyme in the phenazine-biosynthesis pathway from Pseudomonas fluorescens 2-79. Acta crystallographica. Section D, Biological crystallography 20040101
In silico identification and experimental validation of PmrAB targets in Salmonella typhimurium by regulatory motif detection. Genome biology 20040101
Network analysis of metabolic enzyme evolution in Escherichia coli. BMC bioinformatics 20040101
In vitro reconstitution of rice anthranilate synthase: distinct functional properties of the alpha subunits OASA1 and OASA2. Plant molecular biology 20040101
A homotropic two-state model and auto-antagonism. BMC pharmacology 20040101
New enzymes from combinatorial library modules. Methods in enzymology 20040101
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Integrating phenotypic and expression profiles to map arsenic-response networks. Genome biology 20040101
Quantitative evaluation of noncovalent chorismate mutase-inhibitor binding by ESI-MS. Journal of the American Society for Mass Spectrometry 20031201
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(De)regulation of key enzyme steps in the shikimate pathway and phenylalanine-specific pathway of the actinomycete Amycolatopsis methanolica. Microbiology (Reading, England) 20031101
Crystal structure of Mycobacterium tuberculosis MenB, a key enzyme in vitamin K2 biosynthesis. The Journal of biological chemistry 20031024
(S,S)-2,3-Dihydroxy-2,3-dihydrobenzoic acid: microbial access with engineered cells of Escherichia coli and application as starting material in natural-product synthesis. Chemistry (Weinheim an der Bergstrasse, Germany) 20030905
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Easy access to (R,R)-3,4-dihydroxy-3,4-dihydrobenzoic acid with engineered strains of Escherichia coli. Chembiochem : a European journal of chemical biology 20030804
The salicylic acid loop in plant defense. Current opinion in plant biology 20030801
An engineered chorismate mutase with allosteric regulation. Bioorganic & medicinal chemistry 20030717
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Investigation of solvent effects for the Claisen rearrangement of chorismate to prephenate: mechanistic interpretation via near attack conformations. Journal of the American Chemical Society 20030604
A novel strategy for the assignment of side-chain resonances in completely deuterated large proteins using 13C spectroscopy. Journal of biomolecular NMR 20030601
Regulation of anthraquinone biosynthesis in cell cultures of Morinda citrifolia. Journal of plant physiology 20030601
Structure and mechanism of Pseudomonas aeruginosa PhzD, an isochorismatase from the phenazine biosynthetic pathway. Biochemistry 20030520
HutC/FarR-like bacterial transcription factors of the GntR family contain a small molecule-binding domain of the chorismate lyase fold. FEMS microbiology letters 20030516
Charge optimization increases the potency and selectivity of a chorismate mutase inhibitor. Journal of the American Chemical Society 20030514
Comparison of formation of reactive conformers (NACs) for the Claisen rearrangement of chorismate to prephenate in water and in the E. coli mutase: the efficiency of the enzyme catalysis. Journal of the American Chemical Society 20030514
Isochorismate synthase (PchA), the first and rate-limiting enzyme in salicylate biosynthesis of Pseudomonas aeruginosa. The Journal of biological chemistry 20030509
Quinic acid induces hypovirulence and expression of a hypovirulence-associated double-stranded RNA in Rhizoctonia solani. Current genetics 20030501
Genetic organization of an Acinetobacter baumannii chromosomal region harbouring genes related to siderophore biosynthesis and transport. Microbiology (Reading, England) 20030501
A chorismate mutase from the soybean cyst nematode Heterodera glycines shows polymorphisms that correlate with virulence. Molecular plant-microbe interactions : MPMI 20030501
On the generation of catalytic antibodies by transition state analogues. Chembiochem : a European journal of chemical biology 20030404
Understanding the role of active-site residues in chorismate mutase catalysis from molecular-dynamics simulations. Angewandte Chemie (International ed. in English) 20030404
Selective stabilization of the chorismate mutase transition state by a positively charged hydrogen bond donor. Journal of the American Chemical Society 20030319
Crystallization and preliminary X-ray crystallographic studies of chorismate synthase from Helicobacter pylori. Acta crystallographica. Section D, Biological crystallography 20030301
Construction and complementation of the first auxotrophic mutant in the spirochaete Leptospira meyeri. Microbiology (Reading, England) 20030301
Preorganization and reorganization as related factors in enzyme catalysis: the chorismate mutase case. Chemistry (Weinheim an der Bergstrasse, Germany) 20030217
Enzymes do what is expected (chalcone isomerase versus chorismate mutase). Journal of the American Chemical Society 20030212
QM/MM calculations of kinetic isotope effects in the chorismate mutase active site. Organic & biomolecular chemistry 20030207
Meloidogyne javanica chorismate mutase 1 alters plant cell development. Molecular plant-microbe interactions : MPMI 20030201
Mapping of chorismate mutase and prephenate dehydrogenase domains in the Escherichia coli T-protein. European journal of biochemistry 20030201
Deletion of Aspergillus nidulans aroC using a novel blaster module that combines ET cloning and marker rescue. Molecular genetics and genomics : MGG 20030201
A new strategy for backbone resonance assignment in large proteins using a MQ-HACACO experiment. Journal of biomolecular NMR 20030201
Metabolic engineering. Researchers create first autonomous synthetic life form. Science (New York, N.Y.) 20030131
Solution structure and functional ligand screening of HI0719, a highly conserved protein from bacteria to humans in the YjgF/YER057c/UK114 family. Biochemistry 20030114
Microarray analysis of orthologous genes: conservation of the translational machinery across species at the sequence and expression level. Genome biology 20030101
Lateral gene transfer and ancient paralogy of operons containing redundant copies of tryptophan-pathway genes in Xylella species and in heterocystous cyanobacteria. Genome biology 20030101
Horizontally transferred genes in plant-parasitic nematodes: a high-throughput genomic approach. Genome biology 20030101
Characterization of a chorismate mutase from the potato cyst nematode Globodera pallida. Molecular plant pathology 20030101
Longitudinal (1)H relaxation optimization in TROSY NMR spectroscopy. Journal of the American Chemical Society 20021030
The common aromatic amino acid biosynthesis pathway is essential in Mycobacterium tuberculosis. Microbiology (Reading, England) 20021001
Investigation of the enzymatic and nonenzymatic cope rearrangement of carbaprephenate to carbachorismate. The Journal of organic chemistry 20020920
Direct NMR observation and DFT calculations of a hydrogen bond at the active site of a 44 kDa enzyme. Journal of biomolecular NMR 20020901
High level expression of chorismate pyruvate-lyase (UbiC) and HMG-CoA reductase in hairy root cultures of Lithospermum erythrorhizon. Plant & cell physiology 20020801
Salicylate biosynthesis in Pseudomonas aeruginosa. Purification and characterization of PchB, a novel bifunctional enzyme displaying isochorismate pyruvate-lyase and chorismate mutase activities. The Journal of biological chemistry 20020614
Thermodynamics of reactions catalyzed by PABA synthase. Biophysical chemistry 20020410
Probing the overlap of chorismate mutase and prephenate dehydrogenase sites in the escherichia coli T-protein: a dehydrogenase-selective inhibitor. Bioorganic & medicinal chemistry letters 20020325
The correct phylogenetic relationship of KdsA (3-deoxy-d-manno-octulosonate 8-phosphate synthase) with one of two independently evolved classes of AroA (3-deoxy-d-arabino-heptulosonate 7-phosphate synthase). Journal of molecular evolution 20020301
Examination of Salmonella gene expression in an infected mammalian host using the green fluorescent protein and two-colour flow cytometry. Molecular microbiology 20020301
Structure of Escherichia coli aminodeoxychorismate synthase: architectural conservation and diversity in chorismate-utilizing enzymes. Biochemistry 20020219
The shikimate pathway and its branches in apicomplexan parasites. The Journal of infectious diseases 20020215
A genetic algorithm for the identification of conformationally invariant regions in protein molecules. Acta crystallographica. Section D, Biological crystallography 20020201
RNA interference (RNAi) inhibits growth of Plasmodium falciparum. Molecular and biochemical parasitology 20020201
Chorismate lyase: kinetics and engineering for stability. Biochimica et biophysica acta 20020131
Biosynthesis of anthraquinones in cell cultures of Cinchona 'Robusta' proceeds via the methylerythritol 4-phosphate pathway. Phytochemistry 20020101
Significance of two distinct types of tryptophan synthase beta chain in Bacteria, Archaea and higher plants. Genome biology 20020101
Evolution of gene fusions: horizontal transfer versus independent events. Genome biology 20020101
Nonlinear dynamics of regulation of bacterial trp operon: model analysis of integrated effects of repression, feedback inhibition, and attenuation. Biotechnology progress 20020101
Dynamic diversity of the tryptophan pathway in chlamydiae: reductive evolution and a novel operon for tryptophan recapture. Genome biology 20020101
Clustering of isochorismate synthase genes menF and entC and channeling of isochorismate in Escherichia coli. Biochimica et biophysica acta 20011230
Microbial synthesis of p-hydroxybenzoic acid from glucose. Biotechnology and bioengineering 20011201
Isochorismate synthase is required to synthesize salicylic acid for plant defence. Nature 20011129
Spectroscopic and kinetic characterization of the bifunctional chorismate synthase from Neurospora crassa: evidence for a common binding site for 5-enolpyruvylshikimate 3-phosphate and NADPH. The Journal of biological chemistry 20011116
Studies on 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase using chorismate mutase inhibitors. Bioorganic & medicinal chemistry letters 20011105
The gene cluster for chloramphenicol biosynthesis in Streptomyces venezuelae ISP5230 includes novel shikimate pathway homologues and a monomodular non-ribosomal peptide synthetase gene. Microbiology (Reading, England) 20011001
Ubiquinone biosynthesis in microorganisms. FEMS microbiology letters 20010925
A selective inhibitor of Escherichia coli prephenate dehydratase. Bioorganic & medicinal chemistry letters 20010917
The crystal structure of chorismate lyase shows a new fold and a tightly retained product. Proteins 20010815
New insights into the metal center of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase. Biochemistry 20010727
The biosynthesis of shikimate metabolites. Natural product reports 20010601
TROSY NMR with partially deuterated proteins. Journal of biomolecular NMR 20010601
Chorismate synthase from the hyperthermophile Thermotoga maritima combines thermostability and increased rigidity with catalytic and spectral properties similar to mesophilic counterparts. The Journal of biological chemistry 20010525
Subcellular localization and characterization of chorismate synthase in the apicomplexan Plasmodium falciparum. Molecular microbiology 20010401
Anthranilate synthase without an LLES motif from a hyperthermophilic archaeon is inhibited by tryptophan. Biochemical and biophysical research communications 20010309
A hybrid potential reaction path and free energy study of the chorismate mutase reaction. Journal of the American Chemical Society 20010227
Biosynthesis of menaquinone (vitamin K2) and ubiquinone (coenzyme Q): a perspective on enzymatic mechanisms. Vitamins and hormones 20010101
Manipulation of salicylate content in Arabidopsis thaliana by the expression of an engineered bacterial salicylate synthase. The Plant journal : for cell and molecular biology 20010101
A metabolic node in action: chorismate-utilizing enzymes in microorganisms. Critical reviews in microbiology 20010101
The emerging periplasm-localized subclass of AroQ chorismate mutases, exemplified by those from Salmonella typhimurium and Pseudomonas aeruginosa. Genome biology 20010101
CASP2 knowledge-based approach to distant homology recognition and fold prediction in CASP4. Proteins 20010101
Escherichia coli chorismate synthase catalyzes the conversion of (6S)-6-fluoro-5-enolpyruvylshikimate-3-phosphate to 6-fluorochorismate. Implications for the enzyme mechanism and the antimicrobial action of (6S)-6-fluoroshikimate. The Journal of biological chemistry 19950929
Biosynthesis of o-succinylbenzoic acid in Bacillus subtilis: identification of menD mutants and evidence against the involvement of the alpha-ketoglutarate dehydrogenase complex. Journal of bacteriology 19940501
Routes to catalysis: structure of a catalytic antibody and comparison with its natural counterpart. Science (New York, N.Y.) 19940204
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Vitamin K (menaquinone) biosynthesis in bacteria: high-performance liquid chromatographic assay of the overall synthesis of o-succinylbenzoic acid and of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid synthase. Analytical biochemistry 19890501
Biosynthesis of o-succinylbenzoic acid. I: Cell free synthesis of o-succinylbenzoic acid from isochorismic acid in enzyme preparations from vitamin K producing bacteria. Archives of biochemistry and biophysics 19870701
Incorporation of chorismic acid and 4-aminobenzoic acid into the 4-hydroxyaniline moiety of N-(gamma-L-glutamyl)-4-hydroxyaniline in Agaricus bisporus. Biochimica et biophysica acta 19850618
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