1-[(4-chlorobenzene)sulfonyl]-3-propylurea
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Discriminating between adaptive and carcinogenic liver hypertrophy in rat studies using logistic ridge regression analysis of toxicogenomic data: The mode of action and predictive models. | Toxicology and applied pharmacology 20170301 |
A correlation between the in vitro drug toxicity of drugs to cell lines that express human P450s and their propensity to cause liver injury in humans. | Toxicological sciences : an official journal of the Society of Toxicology 20140101 |
β-catenin confers resistance to PI3K and AKT inhibitors and subverts FOXO3a to promote metastasis in colon cancer. | Nature medicine 20120601 |
Inhibition of protein kinase B activity induces cell cycle arrest and apoptosis during early G₁ phase in CHO cells. | Cell biology international 20120401 |
Pharmacogenomic analysis of ATP-sensitive potassium channels coexpressing the common type 2 diabetes risk variants E23K and S1369A. | Pharmacogenetics and genomics 20120301 |
Epac2: a sulfonylurea receptor? | Biochemical Society transactions 20120201 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). | PLoS computational biology 20111201 |
Differential regulation of CIDEA and CIDEC expression by insulin via Akt1/2- and JNK2-dependent pathways in human adipocytes. | Journal of lipid research 20110801 |
Species independence in brain tissue binding using brain homogenates. | Drug metabolism and disposition: the biological fate of chemicals 20110701 |
Evaluation and modeling of the eutectic composition of various drug-polyethylene glycol solid dispersions. | Pharmaceutical development and technology 20110601 |
Targeting the AKT/GSK3β/cyclin D1/Cdk4 survival signaling pathway for eradication of tumor radioresistance acquired by fractionated radiotherapy. | International journal of radiation oncology, biology, physics 20110601 |
Solid-state transformations in the β-form of chlorpropamide on cooling to 100 K. | Acta crystallographica. Section B, Structural science 20110401 |
High dose astaxanthin lowers blood pressure and increases insulin sensitivity in rats: are these effects interdependent? | International journal of medical sciences 20110101 |
Error-related functional connectivity of the habenula in humans. | Frontiers in human neuroscience 20110101 |
A predictive ligand-based Bayesian model for human drug-induced liver injury. | Drug metabolism and disposition: the biological fate of chemicals 20101201 |
Antidiabetic properties of ethanolic extract of Cnidoscolus aconitifolius on alloxan induced diabetes mellitus in rats. | African journal of medicine and medical sciences 20101201 |
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. | Bioorganic & medicinal chemistry letters 20101101 |
A combined spectroscopic and crystallographic approach to probing drug-human serum albumin interactions. | Bioorganic & medicinal chemistry 20101101 |
Ameliorative effects of Cnidoscolus aconitifolius on alloxan toxicity in Wistar rats. | African health sciences 20100901 |
Small scale screening to determine the ability of different polymers to inhibit drug crystallization upon rapid solvent evaporation. | Molecular pharmaceutics 20100802 |
Evaluation of the microstructure of semicrystalline solid dispersions. | Molecular pharmaceutics 20100802 |
Crystallization and polymorphic transitions of chlorpropamide in aqueous 2-hydroxybutyl-beta-cyclodextrin solution. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20100219 |
AKT controls human first trimester trophoblast cell sensitivity to FAS-mediated apoptosis by regulating XIAP expression. | Biology of reproduction 20100101 |
Oral lichenoid drug reaction associated with antihypertensive and hypoglycemic drugs. | Journal of drugs in dermatology : JDD 20100101 |
Neurofilament heavy polypeptide regulates the Akt-beta-catenin pathway in human esophageal squamous cell carcinoma. | PloS one 20100101 |
Maitake mushroom extracts ameliorate progressive hypertension and other chronic metabolic perturbations in aging female rats. | International journal of medical sciences 20100101 |
Radiation burn caused by indoor tanning light. | Journal of burn care & research : official publication of the American Burn Association 20100101 |
A conformational polymorphic transition in the high-temperature epsilon-form of chlorpropamide on cooling: a new epsilon'-form. | Acta crystallographica. Section B, Structural science 20091201 |
Metformin use and prostate cancer in Caucasian men: results from a population-based case-control study. | Cancer causes & control : CCC 20091101 |
Quantitative 35Cl nuclear quadrupole resonance in tablets of the antidiabetic medicine Diabinese. | Analytical chemistry 20090701 |
Leptin exerts an anti-apoptotic effect on human dendritic cells via the PI3K-Akt signaling pathway. | FEBS letters 20090402 |
NMR search for polymorphic phase transformations in chlorpropamide form-A at high pressures. | Journal of pharmaceutical sciences 20090401 |
Apoptosis of metastatic prostate cancer cells by a combination of cyclin-dependent kinase and AKT inhibitors. | The international journal of biochemistry & cell biology 20090301 |
The role of Akt/protein kinase B subtypes in retinal ischemic preconditioning. | Experimental eye research 20090301 |
Comprehensive in silico prediction and analysis of chlamydial outer membrane proteins reflects evolution and life style of the Chlamydiae. | BMC genomics 20090101 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. | Journal of medicinal chemistry 20081113 |
Chlorpropamide treatment restores the reduced carrageenan-induced paw edema and pleural exudate volume in diabetic rats. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20080901 |
Gingival crevicular fluid PGE2, IL-1beta, t-PA, PAI-2 levels in type 2 diabetes and relationship with periodontal disease. | Clinical biochemistry 20080701 |
Studying the human brain anatomical network via diffusion-weighted MRI and Graph Theory. | NeuroImage 20080415 |
Effect of Nigerian meals on the pharmacokinetics of chlorpropamide in type II diabetic patients. | European journal of drug metabolism and pharmacokinetics 20080101 |
The influence of lamivudine, stavudine and nevirapine on the pharmacokinetics of chlorpropamide in human subjects. | European journal of drug metabolism and pharmacokinetics 20080101 |
Hypoglycaemic and hypolipidaemic effect of aqueous leaf extract of Murraya koenigii in normal and alloxan-diabetic rats. | Nigerian journal of physiological sciences : official publication of the Physiological Society of Nigeria 20080101 |
Shp2E76K mutant confers cytokine-independent survival of TF-1 myeloid cells by up-regulating Bcl-XL. | The Journal of biological chemistry 20071214 |
The influence of improved glycaemic control with chlorpropamide on microvascular reactivity and nitric oxide synthase activity in diabetic rats. | The Journal of pharmacy and pharmacology 20070801 |
A new gamma-polymorph of chlorpropamide: 4-chloro-N-(propylaminocarbonyl)benzenesulfonamide. | Acta crystallographica. Section C, Crystal structure communications 20070601 |
Three-dimensional quantitative structure-activity relationship analysis of human CYP51 inhibitors. | Drug metabolism and disposition: the biological fate of chemicals 20070301 |
Solubility measurement of polymorphic compounds via the pH-metric titration technique. | International journal of pharmaceutics 20070207 |
Hypogycaemia without coma. | Journal of the Indian Medical Association 20070201 |
Inhibition by natural dietary substances of gastrointestinal absorption of starch and sucrose in rats and pigs: 1. Acute studies. | International journal of medical sciences 20070101 |
Inhibition by natural dietary substances of gastrointestinal absorption of starch and sucrose in rats 2. Subchronic studies. | International journal of medical sciences 20070101 |
Effect of pressure up to 5.5GPa on dry powder samples of chlorpropamide form-A. | International journal of pharmaceutics 20061211 |
Low level determination of p-toluenesulfonate and benzenesulfonate esters in drug substance by high performance liquid chromatography/mass spectrometry. | Journal of chromatography. A 20060630 |
[Syndrome of inappropriate secretion of antidiuretic hormone]. | Nihon rinsho. Japanese journal of clinical medicine 20060528 |
Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 |
Depth profiling of compression-induced disorders and polymorphic transition on tablet surfaces with grazing incidence X-ray diffraction. | Pharmaceutical research 20060401 |
Hypoglycaemic and hypotensive effects of Harpephyllum caffrum Bernh ex CF Krauss (Anacardiaceae) stem-bark aqueous extract in rats. | Cardiovascular journal of South Africa : official journal for Southern Africa Cardiac Society [and] South African Society of Cardiac Practitioners 20060101 |
Hypoglycaemic and hypotensive effects of Momordica charantia Linn (Cucurbitaceae) whole-plant aqueous extract in rats. | Cardiovascular journal of South Africa : official journal for Southern Africa Cardiac Society [and] South African Society of Cardiac Practitioners 20060101 |
Antiinflammatory, analgesic and hypoglycemic effects of Mangifera indica Linn. (Anacardiaceae) stem-bark aqueous extract. | Methods and findings in experimental and clinical pharmacology 20051001 |
Experimental antihyperglycemic effect of diterpenoids of llareta Azorella compacta (Umbelliferae) Phil in rats. | Phytotherapy research : PTR 20050801 |
Utilization of pure nuclear quadrupole resonance spectroscopy for the study of pharmaceutical crystal forms. | International journal of pharmaceutics 20050714 |
Chlorpropamide 2-hydroxylation is catalysed by CYP2C9 and CYP2C19 in vitro: chlorpropamide disposition is influenced by CYP2C9, but not by CYP2C19 genetic polymorphism. | British journal of clinical pharmacology 20050501 |
Predicting human serum albumin affinity of interleukin-8 (CXCL8) inhibitors by 3D-QSPR approach. | Journal of medicinal chemistry 20050407 |
Antihyperglycemics during the perioperative period. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20050301 |
Effects of prolonged in vitro exposure to sulphonylureas on the function and survival of human islets. | Journal of diabetes and its complications 20050101 |
LC/MS/MS method for the analysis of acrylamide and glycidamide hemoglobin adducts. | Advances in experimental medicine and biology 20050101 |
The advantages and disadvantages of a 'herbal' medicine in a patient with diabetes mellitus: a case report. | Diabetic medicine : a journal of the British Diabetic Association 20040601 |
The effect of deinsuring chlorpropamide on the prescribing of oral antihyperglycemics for Nova Scotia Seniors' Pharmacare beneficiaries. | Pharmacotherapy 20040601 |
Effect of the chlorpropamide and fructose-1,6-bisphosphate of soluble TNF receptor II levels. | Pharmacological research 20040501 |
Hypoglycemic effect of Sclerocarya birrea [(A. Rich.) Hochst.] [Anacardiaceae] stem-bark aqueous extract in rats. | Phytomedicine : international journal of phytotherapy and phytopharmacology 20031101 |
Effect of the aqueous extract of Chrysanthellum indicum on calcium mobilization and activation of rat portal vein. | Journal of ethnopharmacology 20030901 |
Selection of drugs to test the specificity of the Tg.AC assay by screening for induction of the gadd153 promoter in vitro. | Toxicological sciences : an official journal of the Society of Toxicology 20030801 |
Functional recovery after surgical resection of low grade gliomas in eloquent brain: hypothesis of brain compensation. | Journal of neurology, neurosurgery, and psychiatry 20030701 |
Quantitative determination of polymorphic composition in intact compacts by parallel-beam X-ray powder diffractometry. | Journal of pharmaceutical and biomedical analysis 20021107 |
Coefficient of failure: a methodology for examining longitudinal beta-cell function in Type 2 diabetes. | Diabetic medicine : a journal of the British Diabetic Association 20020601 |
Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells. | The Journal of biological chemistry 20020419 |
Crystal doping aided by rapid expansion of supercritical solutions. | AAPS PharmSciTech 20020201 |
Investigation of hypoglycemic properties of rectal suppositories with chlorpropamide. | Acta poloniae pharmaceutica 20020101 |
Inhibition of ALDH3A1-catalyzed oxidation by chlorpropamide analogues. | Chemico-biological interactions 20011128 |
Hypodipsic hypernatremia and diabetes insipidus following anterior communicating artery aneurysm clipping: diagnostic and therapeutic challenges in the amnestic rehabilitation patient. | Brain injury 20011101 |
Quality indicators for appropriate medication use in vulnerable elders. | Annals of internal medicine 20011016 |
Differences in pharmacotherapy and in glucose control of type 2 diabetes patients in two neighbouring towns: a longitudinal population-based study. | Diabetes, obesity & metabolism 20010801 |
Inhibition of ALDH3A1-catalyzed oxidation by chlorpropamide analogues. | Chemico-biological interactions 20010130 |
Modulation by drugs of human hepatic sodium-dependent bile acid transporter (sodium taurocholate cotransporting polypeptide) activity. | The Journal of pharmacology and experimental therapeutics 19991201 |
The structure and function of the ATP-sensitive K+ channel in insulin-secreting pancreatic beta-cells. | Journal of molecular endocrinology 19990401 |
[Hepatotoxic reaction associated with metformin and chlorpropamide treatment]. | Revista clinica espanola 19990201 |
Correlating structure and function in ATP-sensitive K+ channels. | Trends in neurosciences 19980701 |
Chlorpropamide-induced cholestatic liver failure resulting in death. | Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 19960101 |
Chlorpropamide-induced ADH release, hyponatremia and central pontine myelinolysis in diabetes mellitus. | The Tohoku journal of experimental medicine 19951201 |
Reconstitution of IKATP: an inward rectifier subunit plus the sulfonylurea receptor. | Science (New York, N.Y.) 19951117 |
Hypertension secondary to chlorpropamide with amelioration by changing to insulin. | American journal of hypertension 19930401 |
Chlorpropamide-induced hyponatremia in the veteran population. | The Annals of pharmacotherapy 19921001 |
Chlorpropamide induced syndrome of inappropriate secretion of antidiuretic hormone. | The Journal of the Association of Physicians of India 19910801 |
Chlorpropamide or chlorpromazine? | CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 19910115 |
Prolonged cholestasis and disappearance of interlobular bile ducts following chlorpropamide and erythromycin ethylsuccinate. Case of drug interaction? | Liver 19881201 |
The mechanisms of sulfonylurea-induced immune hemolysis: case report and review of the literature. | American journal of hematology 19861101 |
A case of chronic liver disease due to tolazamide. | Gastroenterology 19850701 |
Chlorpropamide-induced cholestatic jaundice and pseudomembranous colitis. | The American journal of gastroenterology 19850501 |
Incidence of severe sideeffects during therapy with sulfonylureas and biguanides. | Hormone and metabolic research. Supplement series 19850101 |
Chlorpropamide-induced hemolytic anemia. | Drug intelligence & clinical pharmacy 19841201 |
Acute hemolytic anemia associated with a chlorpropamide-induced apparent auto-anti-Jka. | Transfusion 19840101 |
The effect of chlorpropamide hyponatremia on mental status in a nursing home population. | The Journal of family practice 19830501 |
Nephrotic syndrome and immune complex glomerulonephritis associated with chlorpropamide therapy. | The American journal of medicine 19830201 |
Chlorpropamide-induced hypoglycemia. A dramatic presentation of celiac disease. | JAMA 19820212 |
Chlorpropamide-induced optic neuropathy. | Archives of internal medicine 19820201 |
Chlorpropamide-induced Syndrome of Inappropriate Antidiuretic Hormone Secretion. | Journal of the American Geriatrics Society 19810701 |
Chlorpropamide-induced haemolytic anaemia. | Postgraduate medical journal 19810101 |
Tolazamide-induced cholestasis. | Southern medical journal 19800801 |
Megaloblastic anaemia due to vitamin B12 malabsorption associated with long-term metformin treatment. | British medical journal 19800517 |
Chlorpropamide-induced pure RBC aplasia. | Archives of internal medicine 19800501 |
Hypoglycemic coma, jaundice, and pure RBC aplasia following chlorpropamide therapy. | Archives of internal medicine 19800501 |
Chlorpropamide induced syndrome of inappropriate antidiuretic hormone secretion. | Journal of postgraduate medicine 19800401 |
Reduction of the severity of nephropathy in aging Fischer 344 rats treated with analogs of arylsulfonyluria. | Toxicology and applied pharmacology 19790701 |
Chlorpropamide-alcohol flushing: a dominantly inherited trait associated with diabetes. | British medical journal 19781202 |
Chlorpropamide-alcohol flushing: a definition of its relation to non-insulin-dependent diabetes. | British medical journal 19781202 |
Encephalopathy induced by oral hypoglycemic drugs. | Archives of internal medicine 19770801 |
Effect of antidiuretic drugs in rats with lithium-induced polyuria. | Acta pharmacologica et toxicologica 19760201 |
Postoperative hypoglycaemic coma associated with chlorpropamide. | British journal of anaesthesia 19750801 |
On the mechanism of lithium-induced diabetes insipidus in man and the rat. | The Journal of clinical investigation 19740401 |
[Case of hypoglycemic coma in a female patient with diabetes insipidus treated with chlorpropamide]. | Endokrynologia Polska 19740101 |
Chlorpropamide and angina pectoris. | Annals of internal medicine 19730301 |
Inappropriate secretion of antidiuretic hormone induced by chlorpropamide. | The American journal of the medical sciences 19720301 |
Severe hypoglycaemic shock caused by chlorpropamide. (Case report). | The Journal of the Association of Physicians of India 19710101 |
Chlorpropamide-induced immune hemolytic anemia. | The New England journal of medicine 19701022 |
Pure red blood cell aplasia associated with chlorpropamide therapy. Patient summary and review of the literature. | Archives of internal medicine 19690401 |
[Cytopenias caused by hypoglycemic sulfonamides]. | Journees annuelles de diabetologie de l'Hotel-Dieu 19680101 |
Haemolysis and agranulocytosis complicating treatment with methyldopa. | British medical journal 19671014 |