(2R)-2-amino-3-[(carboxymethyl)sulfanyl]propanoic acid
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Synthesis, chemical identification, antioxidant capacities and immunological evaluation studies of a novel silver(I) carbocysteine complex. | Chemico-biological interactions 20140905 |
Oxidative stress and innate immunity responses in cigarette smoke stimulated nasal epithelial cells. | Toxicology in vitro : an international journal published in association with BIBRA 20140301 |
Carbocysteine regulates innate immune responses and senescence processes in cigarette smoke stimulated bronchial epithelial cells. | Toxicology letters 20131125 |
S-Carboxyethylcysteine (a constituent of Acacia seed) negatively affects casein protein utilization by rats. | Nutrition (Burbank, Los Angeles County, Calif.) 20120701 |
Drug fever due to S-carboxymethyl-L-cystein: demonstration of a causative agent with patch tests. | The Journal of dermatology 20120601 |
Cigarette smoke enhances chemotaxis via acetylation of proline-glycine-proline. | Frontiers in bioscience (Elite edition) 20120601 |
An investigation into possible xenobiotic-endobiotic inter-relationships involving the amino acid analogue drug, S-carboxymethyl-L-cysteine and plasma amino acids in humans. | Amino acids 20120501 |
S-carboxymethyl-L-cysteine. | Drug metabolism reviews 20120501 |
[Notes on syrups and dry syrups of ambroxol hydrochloride and L-carbocysteine]. | Arerugi = [Allergy] 20120501 |
Carbocisteine promotes phagocytosis of apoptotic cells by alveolar macrophages. | European journal of pharmacology 20120227 |
Efficacy of combined treatment with S-carboxymethylcysteine (carbocisteine) and clarithromycin in chronic rhinosinusitis patients without nasal polyp or with small nasal polyp. | Auris, nasus, larynx 20120201 |
Disulphide linkage in mouse ST6Gal-I: determination of linkage positions and mutant analysis. | Journal of biochemistry 20120201 |
l-carbocisteine inhibits respiratory syncytial virus infection in human tracheal epithelial cells. | Respiratory physiology & neurobiology 20120115 |
S-carboxymethylcysteine inhibits adherence of Streptococcus pneumoniae to human alveolar epithelial cells. | Journal of medical microbiology 20120101 |
Carbocisteine reduces the cytotoxicity of oxaliplatin. | Zeitschrift fur Naturforschung. C, Journal of biosciences 20120101 |
[Expression and role of sugar chains on airway mucus during the exacerbation of airway inflammation]. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20120101 |
The B°AT1 amino acid transporter from rat kidney reconstituted in liposomes: kinetics and inactivation by methylmercury. | Biochimica et biophysica acta 20111001 |
Carbocisteine protects against emphysema induced by cigarette smoke extract in rats. | Chest 20110501 |
A comprehensive understanding of thioTEPA metabolism in the mouse using UPLC-ESI-QTOFMS-based metabolomics. | Biochemical pharmacology 20110415 |
Recombinant heteromeric phenylalanine monooxygenase and the oxygenation of carbon and sulfur substrates. | The Journal of pharmacy and pharmacology 20110401 |
Identification of novel small molecule antimicrobials targeting Mycoplasma bovis. | The Journal of antimicrobial chemotherapy 20110301 |
Respiratory paradoxical adverse drug reactions associated with acetylcysteine and carbocysteine systemic use in paediatric patients: a national survey. | PloS one 20110101 |
Protein modification by dicarbonyl molecular species in neurodegenerative diseases. | Journal of amino acids 20110101 |
Inactivation by Hg2+ and methylmercury of the glutamine/amino acid transporter (ASCT2) reconstituted in liposomes: Prediction of the involvement of a CXXC motif by homology modelling. | Biochemical pharmacology 20101015 |
Comparative metabolism of cyclophosphamide and ifosfamide in the mouse using UPLC-ESI-QTOFMS-based metabolomics. | Biochemical pharmacology 20101001 |
The effect and mechanism of action of carbocysteine on airway bacterial load in rats chronically exposed to cigarette smoke. | Respirology (Carlton, Vic.) 20101001 |
Carbocisteine normalizes the viscous property of mucus through regulation of fucosylated and sialylated sugar chain on airway mucins. | European journal of pharmacology 20100901 |
Inhibitory effects of carbocisteine on type A seasonal influenza virus infection in human airway epithelial cells. | American journal of physiology. Lung cellular and molecular physiology 20100801 |
Effects of combination therapy with montelukast and carbocysteine in allergen-induced airway hyperresponsiveness and airway inflammation. | British journal of pharmacology 20100701 |
[Mucolytic drugs: towards a contraindication in infants]. | Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 20100601 |
Post-translational activation of human phenylalanine 4-monooxygenase from an endobiotic to a xenobiotic enzyme by reactive oxygen and reactive nitrogen species. | Xenobiotica; the fate of foreign compounds in biological systems 20100501 |
The pharmacokinetics of orally administered S-carboxymethyl-L-cysteine in the dog, calf and sheep. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20100219 |
Isoprostanes-biomarkers of lipid peroxidation: their utility in evaluating oxidative stress and analysis. | International journal of molecular sciences 20100101 |
Association between lung function and exacerbation frequency in patients with COPD. | International journal of chronic obstructive pulmonary disease 20100101 |
Modulation of the cellular expression of circulating advanced glycation end-product receptors in type 2 diabetic nephropathy. | Experimental diabetes research 20100101 |
Phenylalanine 4-monooxygenase and the role of endobiotic metabolism enzymes in xenobiotic biotransformation. | Expert opinion on drug metabolism & toxicology 20091001 |
Carbocisteine inhibits oxidant-induced apoptosis in cultured human airway epithelial cells. | Respirology (Carlton, Vic.) 20090901 |
L-carbocisteine reduces neutrophil elastase-induced mucin production. | Respiratory physiology & neurobiology 20090630 |
Carbocysteine: clinical experience and new perspectives in the treatment of chronic inflammatory diseases. | Expert opinion on pharmacotherapy 20090301 |
Acetylcysteine and carbocysteine for acute upper and lower respiratory tract infections in paediatric patients without chronic broncho-pulmonary disease. | The Cochrane database of systematic reviews 20090121 |
Nebulized and oral thiol derivatives for pulmonary disease in cystic fibrosis. | The Cochrane database of systematic reviews 20090121 |
The activity of wild type and mutant phenylalanine hydroxylase with respect to the C-oxidation of phenylalanine and the S-oxidation of S-carboxymethyl-L-cysteine. | Molecular genetics and metabolism 20090101 |
Human phenylalanine monooxygenase and thioether metabolism. | The Journal of pharmacy and pharmacology 20090101 |
Carbocisteine can scavenge reactive oxygen species in vitro. | Respirology (Carlton, Vic.) 20090101 |
Mouse recombinant phenylalanine monooxygenase and the S-oxygenation of thioether substrates. | Journal of biochemical and molecular toxicology 20090101 |
Sequestration of Alkyltin(IV) compounds in aqueous solution: formation, stability, and empirical relationships for the binding of dimethyltin(IV) cation by N- and O-donor ligands. | Bioinorganic chemistry and applications 20090101 |
Measurement of phenylalanine monooxygenase (PAH) activities. | Current protocols in toxicology 20090101 |
The role for S-carboxymethylcysteine (carbocisteine) in the management of chronic obstructive pulmonary disease. | International journal of chronic obstructive pulmonary disease 20081201 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. | Journal of medicinal chemistry 20081113 |
Carbocisteine for acute exacerbations of COPD. | Lancet (London, England) 20081108 |
Carbocisteine for acute exacerbations of COPD. | Lancet (London, England) 20081108 |
Variation in the attachment of Streptococcus pneumoniae to human pharyngeal epithelial cells after treatment with S-carboxymethylcysteine. | Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20080801 |
A PEACE-ful solution to COPD exacerbations? | Lancet (London, England) 20080614 |
Effect of carbocisteine on acute exacerbation of chronic obstructive pulmonary disease (PEACE Study): a randomised placebo-controlled study. | Lancet (London, England) 20080614 |
Glutaraldehyde is an effective cross-linker for production of antibodies against advanced glycation end-products. | Journal of immunological methods 20080520 |
s-Carboxymethylcysteine inhibits carbachol-induced constriction of epithelium-denuded rat and human airway preparations. | Clinical and experimental pharmacology & physiology 20080501 |
Immunological detection of N omega-(Carboxymethyl)arginine by a specific antibody. | Annals of the New York Academy of Sciences 20080401 |
Usefulness of antibodies for evaluating the biological significance of AGEs. | Annals of the New York Academy of Sciences 20080401 |
Immunochemical detection of Nepsilon-(carboxyethyl)lysine using a specific antibody. | Journal of immunological methods 20080320 |
[Bitterness of the mixture of clarithromycin dry syrup and carbocisteine preparation--difference between brand name and generic drugs]. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20080301 |
Influence of various combinations of mucolytic agent and non-ionic surfactant on intestinal absorption of poorly absorbed hydrophilic compounds. | International journal of pharmaceutics 20080212 |
S-CMC-Lys protective effects on human respiratory cells during oxidative stress. | Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20080101 |
Phenylalanine 4-monooxygenase and the S-oxidation of S-carboxymethyl-L-cysteine by human cytosolic fractions. | Drug metabolism and drug interactions 20080101 |
Carbocisteine improves quality of life in patients with chronic obstructive pulmonary disease. | Journal of the American Geriatrics Society 20071101 |
The suppression of enhanced bitterness intensity of macrolide dry syrup mixed with an acidic powder. | Chemical & pharmaceutical bulletin 20071001 |
Mechanisms for the proton mobility-dependent gas-phase fragmentation reactions of S-alkyl cysteine sulfoxide-containing peptide ions. | Journal of the American Society for Mass Spectrometry 20070901 |
Bacterial lysate in the prevention of acute exacerbation of COPD and in respiratory recurrent infections. | International journal of chronic obstructive pulmonary disease 20070901 |
Plasma protein advanced glycation end products, carboxymethyl cysteine, and carboxyethyl cysteine, are elevated and related to nephropathy in patients with diabetes. | Molecular and cellular biochemistry 20070801 |
[A possible case of drug-induced pneumonia due to L-carbocisteine]. | Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society 20070801 |
Synthesis and biological evaluation of L-cysteine derivatives as mitotic kinesin Eg5 inhibitors. | Bioorganic & medicinal chemistry letters 20070715 |
Fluorimetric determination of some sulfur containing compounds through complex formation with terbium (Tb+3) and uranium (U+3). | Journal of fluorescence 20070501 |
Carbocisteine: frequent cutaneous adverse effects. | Prescrire international 20070201 |
Reduction and s-carboxymethylation of proteins: large-scale method. | CSH protocols 20070201 |
Protein and low molecular mass thiols as targets and inhibitors of glycation reactions. | Chemical research in toxicology 20061201 |
Carbocysteine therapy in older people with chronic obstructive pulmonary disease. | Journal of the American Geriatrics Society 20061101 |
Evidence for inactivation of cysteine proteases by reactive carbonyls via glycation of active site thiols. | The Biochemical journal 20060901 |
Carbocisteine inhibits rhinovirus infection in human tracheal epithelial cells. | The European respiratory journal 20060701 |
Antioxidant therapeutic targets in COPD. | Current drug targets 20060601 |
Ambroxol for the prevention of acute upper respiratory disease. | Clinical and experimental medicine 20060601 |
A phase II study with antioxidants, both in the diet and supplemented, pharmaconutritional support, progestagen, and anti-cyclooxygenase-2 showing efficacy and safety in patients with cancer-related anorexia/cachexia and oxidative stress. | Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20060501 |
A comparative bioavailability study of a generic capsule formulation containing carbocysteine. | Die Pharmazie 20060501 |
Efficacy of S-carboxymethyl-L-cysteine for otitis media with effusion. | Ear, nose, & throat journal 20060501 |
The sulphoxidation of S-carboxymethyl-L-cysteine in COPD. | The European respiratory journal 20060401 |
Cerebral formation in situ of S-carboxymethylcysteine after ifosfamide administration to mice: a further clue to the mechanism of ifosfamide encephalopathy. | Toxicology letters 20060301 |
Antioxidant therapies in COPD. | International journal of chronic obstructive pulmonary disease 20060301 |
Thiodiglycolic acid and dermatological reactions following S-carboxymethyl-L-cysteine administration. | The British journal of dermatology 20060201 |
Carbocisteine reduces frequency of common colds and exacerbations in patients with chronic obstructive pulmonary disease. | Journal of the American Geriatrics Society 20060201 |
Effects of carbocisteine on sialyl-Lewis x expression in an airway carcinoma cell line stimulated with tumor necrosis factor-alpha. | European journal of pharmacology 20060120 |
S-CMC-Lys-dependent stimulation of electrogenic glutathione secretion by human respiratory epithelium. | Journal of molecular medicine (Berlin, Germany) 20060101 |
Synergistic effect of interleukin 1 alpha on nontypeable Haemophilus influenzae-induced up-regulation of human beta-defensin 2 in middle ear epithelial cells. | BMC infectious diseases 20060101 |
High-throughput determination of carbocysteine in human plasma by liquid chromatography/tandem mass spectrometry: application to a bioequivalence study of two formulations in healthy volunteers. | Rapid communications in mass spectrometry : RCM 20060101 |
An occupational hygiene investigation of exposure to acrylamide and the role for urinary S-carboxyethyl-cysteine (CEC) as a biological marker. | The Annals of occupational hygiene 20051101 |
S-carboxymethylcysteine normalises airway responsiveness in sensitised and challenged mice. | The European respiratory journal 20051001 |
Evidence for the formation of adducts and S-(carboxymethyl)cysteine on reaction of alpha-dicarbonyl compounds with thiol groups on amino acids, peptides, and proteins. | Chemical research in toxicology 20050801 |
Re(CO)(3) complexes synthesized via an improved preparation of aqueous fac-[Re(CO)(3)(H(2)O)(3)](+) as an aid in assessing (99m)Tc imaging agents. Structural characterization and solution behavior of complexes with thioether-bearing amino acids as tridentate ligands. | Inorganic chemistry 20050725 |
Thiodiglycolic acid as a possible causative agent of fixed drug eruption provoked only after continuous administration of S-carboxymethyl-L-cysteine: case report and review of reported cases. | The British journal of dermatology 20050701 |
Effect of glucose concentration on formation of AGEs in erythrocytes in vitro. | Annals of the New York Academy of Sciences 20050601 |
Analysis of plasma amino acids by HPLC with photodiode array and fluorescence detection. | Clinica chimica acta; international journal of clinical chemistry 20050401 |
[Fixed drug eruption and carbocysteine]. | Annales de dermatologie et de venereologie 20050401 |
Phenylalanine 4-monooxygenase and the S-oxidation of S-carboxymethyl-L-cysteine in HepG2 cells. | Drug metabolism and drug interactions 20050101 |
Induction of cysteine dioxygenase activity by oral administration of cysteine analogues to the rat: implications for drug efficacy and safety. | Drug metabolism and drug interactions 20050101 |
Phenylalanine hydroxylase: possible involvement in the S-oxidation of S-carboxymethyl-l-cysteine. | Analytical biochemistry 20041201 |
Exhaled Interleukine-6 and 8-isoprostane in chronic obstructive pulmonary disease: effect of carbocysteine lysine salt monohydrate (SCMC-Lys). | European journal of pharmacology 20041128 |
N-acetylcysteine inhibits Na+ absorption across human nasal epithelial cells. | Journal of cellular physiology 20041001 |
Cancer-related anorexia/cachexia syndrome and oxidative stress: an innovative approach beyond current treatment. | Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20041001 |
Reduced airway inflammation and remodeling in parallel with mucin 5AC protein expression decreased by s-carboxymethylcysteine, a mucoregulant, in the airways of rats exposed to sulfur dioxide. | International archives of allergy and immunology 20040801 |
Lack of congruence between cysteine dioxygenase activity and S-carboxymethyl-L-cysteine S-oxidation activity in rat cytosol. | The Journal of pharmacy and pharmacology 20040801 |
Spectrophotometric determination of penicillamine and carbocisteine based on formation of metal complexes. | Farmaco (Societa chimica italiana : 1989) 20040601 |
Chemical modification of muscle protein in diabetes. | Archives of biochemistry and biophysics 20040515 |
Ion-chromatographic determination of carbocisteine in pharmaceuticals based on non-suppressed conductimetric detection. | Journal of chromatography. A 20040213 |
The effect of cysteine analogues on the excretion of urinary sulphate in the rat following cysteine administration. | Drug metabolism and drug interactions 20040101 |
Phenylalanine 4-monooxygenase and the S-oxidation of S-carboxymethyl-L-cysteine. | Drug metabolism and drug interactions 20040101 |
S-carboxymethylcysteine inhibits the attachment of Streptococcus pneumoniae to human pharyngeal epithelial cells. | Microbial pathogenesis 20030601 |
Effect of carbocysteine on cough reflex to capsaicin in asthmatic patients. | British journal of clinical pharmacology 20030601 |
Thirty-five cases of S-carboxymethylcysteine use in paraquat poisoning. | Veterinary and human toxicology 20030201 |
Determination of carbocysteine in human plasma by liquid chromatography/tandem mass spectrometry employing precolumn derivatization. | Rapid communications in mass spectrometry : RCM 20030101 |
Carbocysteine lysine salt monohydrate (SCMC-LYS) is a selective scavenger of reactive oxygen intermediates (ROIs). | European cytokine network 20030101 |
Subcutaneous interleukin-2 in combination with medroxyprogesterone acetate and antioxidants in advanced cancer responders to previous chemotherapy: phase II study evaluating clinical, quality of life, and laboratory parameters. | Journal of experimental therapeutics & oncology 20030101 |
Neurological toxicity of ifosfamide. | Oncology 20030101 |
An investigation into the inter-relationships of sulphur xeno-biotransformation pathways in Parkinson's and motor neurone diseases. | Drug metabolism and drug interactions 20030101 |
Degradation to sulphate of S-methyl-L-cysteine sulphoxide and S-carboxymethyl-L-cysteine sulphoxide in man. | Drug metabolism and drug interactions 20030101 |
[Mucolytic agents for acute respiratory tract infections in infants: a pharmacoepidemiologic problem?]. | Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 20021101 |
S-carboxymethylcysteine inhibits neutrophil activation mediated by N-formyl-methionyl-leucyl-phenylalanine. | European journal of pharmacology 20020802 |
Prolonged survival after experimental paraquat intoxication: role of alternative antioxidants. | Veterinary and human toxicology 20020201 |
Study on the inhibition of protein production by L-cysteine derivatives of nucleic acid bases. | Nucleic acids research. Supplement (2001) 20020101 |
Insights into the mechanisms of ifosfamide encephalopathy: drug metabolites have agonistic effects on alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)/kainate receptors and induce cellular acidification in mouse cortical neurons. | The Journal of pharmacology and experimental therapeutics 20011201 |
Antioxidant activity of carbocysteine lysine salt monohydrate. | Panminerva medica 20010901 |
Does early detection of otitis media with effusion prevent delayed language development? | Archives of disease in childhood 20010801 |
Effect of fudosteine, a cysteine derivative, on blood flow of tracheal microvasculature increased by airway inflammation. | Environmental toxicology and pharmacology 20010701 |
Effects of carbocysteine on antigen-induced increases in cough sensitivity and bronchial responsiveness in guinea pigs. | The Journal of pharmacology and experimental therapeutics 20010601 |
Direct determination of s-carboxymethyl-l-cysteine in syrups by reversed-phase high-performance liquid chromatography. | Journal of pharmaceutical and biomedical analysis 20010401 |
Modulating effects of mucoregulating drugs on the attachment of Haemophilus influenzae. | Microbial pathogenesis 20010301 |
[Comparative study of effects of anti-infective and respiratory system agents on endogeneous glucocorticoids with macrolides]. | The Japanese journal of antibiotics 20010201 |
[Effects of carbocisteine on airway inflammation and related events in SO2-exposed rats]. | Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society 20010101 |
Chemical and biochemical issues related to X-ray crystallography of the ligand-binding domain of estrogen receptor alpha. | Bioconjugate chemistry 20010101 |
A review of xenobiotic metabolism enzymes in Parkinson's disease and motor neuron disease. | Drug metabolism and drug interactions 20010101 |
S-carboxymethylcysteine in the treatment of glue ear: quantitative systematic review. | BMC family practice 20010101 |
Study about the inhibition of L-cysteine derivatives of nucleic acid bases in protein production. | Nucleic acids research. Supplement (2001) 20010101 |
Transfection of fluorescent probed antisense compounds: L-cysteine derivatives of nucleic acid bases. | Nucleic acids research. Supplement (2001) 20010101 |
A proposed mechanism for chlorpromazine jaundice--defective hepatic sulphoxidation combined with rapid hydroxylation. | Journal of hepatology 19880801 |