Efficient promotion of phosphate diester cleavage by a face-to-face cyclodextrin dimer without metal.

Chemical communications (Cambridge, England) 20120604

Conclusive identification of the oxybutynin-hydrolyzing enzyme in human liver.

Drug metabolism and disposition: the biological fate of chemicals 20120501

Rapid hydrolysis of phosphate ester promoted by Ce(IV) conjugating with a β-cyclodextrin monomer and dimer.

Dalton transactions (Cambridge, England : 2003) 20120421

Human α/β hydrolase domain containing 10 (ABHD10) is responsible enzyme for deglucuronidation of mycophenolic acid acyl-glucuronide in liver.

The Journal of biological chemistry 20120316

Carboxylesterase expression in human dental pulp cells: role in regulation of BisGMA-induced prostanoid production and cytotoxicity.

Acta biomaterialia 20120301

Carboxylesterases 1 and 2 hydrolyze phospho-nonsteroidal anti-inflammatory drugs: relevance to their pharmacological activity.

The Journal of pharmacology and experimental therapeutics 20120201

Phosphodiester cleavage properties of copper(II) complexes of 1,4,7-triazacyclononane ligands bearing single alkyl guanidine pendants.

Inorganic chemistry 20120116

The CphAII protein from Aquifex aeolicus exhibits a metal-dependent phosphodiesterase activity.

Extremophiles : life under extreme conditions 20120101

Vesicles and micelles from amphiphilic zinc(II)-cyclen complexes as highly potent promoters of hydrolytic DNA cleavage.

Journal of the American Chemical Society 20111228

Human arylacetamide deacetylase is responsible for deacetylation of rifamycins: rifampicin, rifabutin, and rifapentine.

Biochemical pharmacology 20111201

Directed evolution combined with rational design increases activity of GpdQ toward a non-physiological substrate and alters the oligomeric structure of the enzyme.

Protein engineering, design & selection : PEDS 20111201

Structural and enzymatic characterization of the streptococcal ATP/diadenosine polyphosphate and phosphodiester hydrolase Spr1479/SapH.

The Journal of biological chemistry 20111014

Structure and mechanism of PhnP, a phosphodiesterase of the carbon-phosphorus lyase pathway.

Biochemistry 20111011

Accurate determination of the anticancer prodrug simmitecan and its active metabolite chimmitecan in various plasma samples based on immediate deactivation of blood carboxylesterases.

Journal of chromatography. A 20110923

Enzymes-based resistant mechanism in pyrethroid resistant and susceptible Aedes aegypti strains from northern Thailand.

Parasitology research 20110901

Evaluation of transport mechanism of prodrugs and parent drugs formed by intracellular metabolism in Caco-2 cells with modified carboxylesterase activity: temocapril as a model case.

Journal of pharmaceutical sciences 20110901

Characterization of recombinant human carboxylesterases: fluorescein diacetate as a probe substrate for human carboxylesterase 2.

Drug metabolism and disposition: the biological fate of chemicals 20110801

Cannabidiol causes activated hepatic stellate cell death through a mechanism of endoplasmic reticulum stress-induced apoptosis.

Cell death & disease 20110601

Efficient plasmid DNA cleavage by copper(II) complexes of 1,4,7-triazacyclononane ligands featuring xylyl-linked guanidinium groups.

Inorganic chemistry 20110516

Contribution of carboxylesterase in hamster to the intestinal first-pass loss and low bioavailability of ethyl piperate, an effective lipid-lowering drug candidate.

Drug metabolism and disposition: the biological fate of chemicals 20110501

Complete genome sequence of Weeksella virosa type strain (9751).

Standards in genomic sciences 20110304

Methyl methacrylate and respiratory sensitization: a critical review.

Critical reviews in toxicology 20110301

A novel asymmetric di-Ni(II) system as a highly efficient functional model for phosphodiesterase: synthesis, structures, physicochemical properties and catalytic kinetics.

Dalton transactions (Cambridge, England : 2003) 20110214

Detection and quantification of carboxylesterase 2 activity by capillary electrophoresis.

Analytical chemistry 20110201

A Baeyer-Villiger oxidation specifically catalyzed by human flavin-containing monooxygenase 5.

Drug metabolism and disposition: the biological fate of chemicals 20110101

Transport and metabolism of (±)-praeruptorin A in Caco-2 cell monolayers.

Xenobiotica; the fate of foreign compounds in biological systems 20110101

Coccolithophores: functional biodiversity, enzymes and bioprospecting.

Marine drugs 20110101

Distinct metal ion requirements for the phosphomonoesterase and phosphodiesterase activities of calf intestinal alkaline phosphatase.

The open biochemistry journal 20110101

Complete genome sequence of Nocardiopsis dassonvillei type strain (IMRU 509).

Standards in genomic sciences 20101231

Involvement of carboxylesterase 1 and 2 in the hydrolysis of mycophenolate mofetil.

Drug metabolism and disposition: the biological fate of chemicals 20101201

Characterization of an ATP-regulated DNA-processing enzyme and thermotolerant phosphoesterase in the radioresistant bacterium Deinococcus radiodurans.

The Biochemical journal 20101001

2',3'-cAMP hydrolysis by metal-dependent phosphodiesterases containing DHH, EAL, and HD domains is non-specific: Implications for PDE screening.

Biochemical and biophysical research communications 20100730

Phosphate diesters cleavage mediated by Ce(IV) complexes self-assembled on gold nanoparticles.

Organic & biomolecular chemistry 20100607

Utility of the carboxylesterase inhibitor bis-para-nitrophenylphosphate (BNPP) in the plasma unbound fraction determination for a hydrolytically unstable amide derivative and agonist of the TGR5 receptor.

Xenobiotica; the fate of foreign compounds in biological systems 20100601

Binding and hydrolysis studies of antitumoural titanocene dichloride and Titanocene Y with phosphate diesters.

Journal of inorganic biochemistry 20100401

Hydrolysis of bis(p-nitrophenyl)phosphate by tetravalent metal complexes with Klaui's oxygen tripodal ligand.

Inorganic chemistry 20100301

The bioremediator glycerophosphodiesterase employs a non-processive mechanism for hydrolysis.

Journal of inorganic biochemistry 20100201

Development of a novel system for estimating human intestinal absorption using Caco-2 cells in the absence of esterase activity.

Drug metabolism and disposition: the biological fate of chemicals 20100201

Ontogeny of acylated ghrelin degradation in the rat.

Peptides 20100201

Hydrolytic cleavage of DNA-model substrates promoted by polyoxovanadates.

Dalton transactions (Cambridge, England : 2003) 20100114

Mechanistic role of each metal ion in Streptomyces dinuclear aminopeptidase: PEPTIDE hydrolysis and 7x10(10)-fold rate enhancement of phosphodiester hydrolysis.

Journal of inorganic biochemistry 20100101

Differential phenotyping of Brucella species using a newly developed semi-automated metabolic system.

BMC microbiology 20100101

Synthesis and kinetic studies of a low-molecular weight organocatalyst for phosphate hydrolysis in water.

Organic & biomolecular chemistry 20091207

Effects of diammonium glycyrrhizinate on the pharmacokinetics of aconitine in rats and the potential mechanism.

Xenobiotica; the fate of foreign compounds in biological systems 20091201

Transport and metabolism of the antitumour drug candidate 2'-benzoyloxycinnamaldehyde in Caco-2 cells.

Xenobiotica; the fate of foreign compounds in biological systems 20091201

Intermetallic communication in titanium(IV) ferrocenyldiketonates.

Inorganic chemistry 20091116

Structural flexibility enhances the reactivity of the bioremediator glycerophosphodiesterase by fine-tuning its mechanism of hydrolysis.

Journal of the American Chemical Society 20090826

Ester hydrolysis by a cyclodextrin dimer catalyst with a tridentate N,N',N''-zinc linking group.

Chemistry, an Asian journal 20090803

Evolution in the amidohydrolase superfamily: substrate-assisted gain of function in the E183K mutant of a phosphotriesterase-like metal-carboxylesterase.

Biochemistry 20090623

Structure of PhnP, a phosphodiesterase of the carbon-phosphorus lyase pathway for phosphonate degradation.

The Journal of biological chemistry 20090619

Influence of carboxylesterase 2 genetic polymorphisms on mycophenolic acid pharmacokinetics in Japanese renal transplant recipients.

Xenobiotica; the fate of foreign compounds in biological systems 20090501

Phosphodiester hydrolysis and specific DNA binding and cleavage promoted by guanidinium-functionalized zinc complexes.

Journal of inorganic biochemistry 20090501

Silica-bound copper(II)triazacyclononane as a phosphate esterase: effect of linker length and surface hydrophobicity.

Dalton transactions (Cambridge, England : 2003) 20090407

Synthesis, structure, magnetic properties and DNA cleavage of binuclear Cu(II) Schiff-base complexes.

Dalton transactions (Cambridge, England : 2003) 20090407

Di-μ-chlorido-bis-[chlorido(1,4,6-trimethyl-6-nitro-1,4-diazepine)copper(II)].

Acta crystallographica. Section E, Structure reports online 20090201

Rapid hydrolysis of model phosphate diesters by alkaline-earth cations in aqueous DMSO: speciation and kinetics.

Dalton transactions (Cambridge, England : 2003) 20081214

Aqueous solutions of transition metal containing micelles.

Advances in colloid and interface science 20081202

A structural and catalytic model for zinc phosphoesterases.

Dalton transactions (Cambridge, England : 2003) 20081121

A phosphate-binding histidine of binuclear metallophosphodiesterase enzymes is a determinant of 2',3'-cyclic nucleotide phosphodiesterase activity.

The Journal of biological chemistry 20081107

Synthesis, X-ray crystal structures, and phosphate ester cleavage properties of bis(2-pyridylmethyl)amine copper(II) complexes with guanidinium pendant groups.

Inorganic chemistry 20081006

Quantitative rat liver function test by galactose single point method.

Laboratory animals 20081001

Pharmacological effects of a novel isosorbide-based butyrylcholinesterase inhibitor.

Chemico-biological interactions 20080925

Cadmium(II) complexes of the glycerophosphodiester-degrading enzyme GpdQ and a biomimetic N,O ligand.

Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20080901

Investigation of the enzyme hydrolysis products of the substrates of alkaline phosphatase in electrochemical immunosensing.

Talanta 20080715

Enzymatic stability of 2'-ethylcarbonate-linked paclitaxel in serum and conversion to paclitaxel by rabbit liver carboxylesterase for use in prodrug/enzyme therapy.

Biopharmaceutics & drug disposition 20080701

Tuning the activity of Zn(II) complexes in DNA cleavage: clues for design of new efficient metallo-hydrolases.

Inorganic chemistry 20080616

1,4,7,10-tetraazacyclododecane metal complexes as potent promoters of phosphodiester hydrolysis under physiological conditions.

Inorganic chemistry 20080602

Role of hydrazine in isoniazid-induced hepatotoxicity in a hepatocyte inflammation model.

Toxicology and applied pharmacology 20080515

Simplified speciation and improved phosphodiesterolytic activity of hydroxo complexes of trivalent lanthanides in aqueous DMSO.

Inorganic chemistry 20080407

Absolute and site-specific quantification of protein phosphorylation using integrated elemental and molecular mass spectrometry: its potential to assess phosphopeptide enrichment procedures.

Analytical chemistry 20080301

Structural and enzymatic characterization of DR1281: A calcineurin-like phosphoesterase from Deinococcus radiodurans.

Proteins 20080215

Crystal structure of Ce(IV)/dipicolinate complex as catalyst for DNA hydrolysis.

Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20080201

(m-Phenyl-enedimethyl-ene)diammonium p-nitro-phenyl-phosphate perchlorate.

Acta crystallographica. Section E, Structure reports online 20080201

Questioning the paradigm of metal complex promoted phosphodiester hydrolysis: [Mo7O24](6-) polyoxometalate cluster as an unlikely catalyst for the hydrolysis of a DNA model substrate.

Chemical communications (Cambridge, England) 20080107

Ester hydrolysis by a cyclodextrin dimer catalyst with a metallophenanthroline linking group.

Chemistry (Weinheim an der Bergstrasse, Germany) 20080101

Metabolism of ciclesonide in the upper and lower airways: review of available data.

Journal of asthma and allergy 20080101

Metal requirements and phosphodiesterase activity of tRNase Z enzymes.

Biochemistry 20071225

Specificity of procaine and ester hydrolysis by human, minipig, and rat skin and liver.

Drug metabolism and disposition: the biological fate of chemicals 20071101

Characterization of a phosphodiesterase capable of hydrolyzing EA 2192, the most toxic degradation product of the nerve agent VX.

Biochemistry 20070807

Intestinal first-pass metabolism via carboxylesterase in rat jejunum and ileum.

Drug metabolism and disposition: the biological fate of chemicals 20070701

Esterase inhibition attribute of grapefruit juice leading to a new drug interaction.

Drug metabolism and disposition: the biological fate of chemicals 20070701

Structural and biochemical characterization of a novel Mn2+-dependent phosphodiesterase encoded by the yfcE gene.

Protein science : a publication of the Protein Society 20070701

The in vitro metabolism of a pyrethroid insecticide, permethrin, and its hydrolysis products in rats.

Toxicology 20070625

Nanosized reactors based on polyethyleneimines: from microheterogeneous systems to immobilized catalysts.

Langmuir : the ACS journal of surfaces and colloids 20070313

Nafamostat is hydrolysed by human liver cytosolic long-chain acyl-CoA hydrolase.

Xenobiotica; the fate of foreign compounds in biological systems 20070301

In vitro characterization of the human biotransformation pathways of aplidine, a novel marine anti-cancer drug.

Investigational new drugs 20070201

Mimicking enzymes: cooperation between organic functional groups and metal ions in the cleavage of phosphate diesters.

Chemistry (Weinheim an der Bergstrasse, Germany) 20070101

Solvent effects and alkali metal ion catalysis in phosphodiester hydrolysis.

The Journal of organic chemistry 20061222

Phosphate ester hydrolysis by hydroxo complexes of trivalent lanthanides stabilized by 4-imidazolecarboxylate.

Inorganic chemistry 20061113

Metallomicellar catalysis: hydrolysis of phosphate monoester and phosphodiester by Cu(II), Zn(II) complexes of pyridyl ligands in CTAB micellar solution.

Journal of colloid and interface science 20061101

Phosphodiester modification by zinc metalated adenine polymer with carboxyl pendants.

Bioorganic & medicinal chemistry letters 20061015

Basicity and coordination properties of a new phenanthroline-based bis-macrocyclic receptor.

Dalton transactions (Cambridge, England : 2003) 20060907

Enhanced hydrolytic activity of Cu(II) and Zn(II) complexes in highly cross-linked polymers.

Dalton transactions (Cambridge, England : 2003) 20060828

Distinct enzymic functional groups are required for the phosphomonoesterase and phosphodiesterase activities of Clostridium thermocellum polynucleotide kinase/phosphatase.

The Journal of biological chemistry 20060714

Comparison of skin esterase activities from different species.

Pharmaceutical research 20060701

Synthesis, reactivities, and magnetostructural properties of FeIII, FeIII-O-FeIII, and ZnIIFeIII-O-FeIIIZnII complexes of a tetraiminodiphenolate macrocycle.

Inorganic chemistry 20060612

Detection of a new N-oxidized metabolite of flutamide, N-[4-nitro-3-(trifluoromethyl)phenyl]hydroxylamine, in human liver microsomes and urine of prostate cancer patients.

Drug metabolism and disposition: the biological fate of chemicals 20060501

Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Involvement of human blood arylesterases and liver microsomal carboxylesterases in nafamostat hydrolysis.

Drug metabolism and pharmacokinetics 20060401

Apoptosis-inducing effects of curcumin derivatives in human bladder cancer cells.

Anti-cancer drugs 20060301

Polyhydroxylated sapphyrins: multisite non-metallic catalysts for activated phosphodiester hydrolysis.

Journal of the American Chemical Society 20060118

Catechol oxidase activity of di-Cu2+-substituted aminopeptidase from Streptomyces griseus.

Journal of the American Chemical Society 20051130

Phosphodiesterase activity of alkaline phosphatase in ATP-initiated Ca(2+) and phosphate deposition in isolated chicken matrix vesicles.

The Journal of biological chemistry 20051104

Macrocyclic lanthanide complexes as artificial nucleases and ribonucleases: effects of pH, metal ionic radii, number of coordinated water molecules, charge, and concentrations of the metal complexes.

Inorganic chemistry 20050919

Stereospecific and regioselective hydrolysis of cannabinoid esters by ES46.5K, an esterase from mouse hepatic microsomes, and its differences from carboxylesterases of rabbit and porcine liver.

Biological & pharmaceutical bulletin 20050901

Vinyl acetate induces intracellular acidification in mouse oral buccal epithelial cells.

Toxicology letters 20050814

Kinetics of phosphodiester cleavage by differently generated cerium(IV) hydroxo species in neutral solutions.

Organic & biomolecular chemistry 20050807

Effect of Zn...Zn separation on the hydrolytic activity of model dizinc phosphodiesterases.

Chemistry (Weinheim an der Bergstrasse, Germany) 20050718

The phosphodiesterase activity of the HmsP EAL domain is required for negative regulation of biofilm formation in Yersinia pestis.

FEMS microbiology letters 20050615

New enzymatic assay using phospholipase D to measure total calcium in serum.

Clinical chemistry 20050601

Identification of a novel keratinocyte retinyl ester hydrolase as a transacylase and lipase.

The Journal of investigative dermatology 20050601

An asymmetric dizinc phosphodiesterase model with phenolate and carboxylate bridges.

Inorganic chemistry 20050516

Exosite modules guide substrate recognition in the ZiPD/ElaC protein family.

The Journal of biological chemistry 20050506

Zinc complex chemistry of N,N,O ligands providing a hydrophobic cavity.

Inorganic chemistry 20050502

Kinetics and mechanism of hydrolysis of a model phosphate diester by [Cu(Me3tacn)(OH2)2]2+ (Me3tacn = 1,4,7-trimethyl-1,4,7-triazacyclononane).

Inorganic chemistry 20050221

Styrene oxide DNA adducts: quantitative determination using 31P monitoring.

Analytical and bioanalytical chemistry 20050101

Effect of carboxylesterase inhibition on the anti-tumour effects of irinotecan.

The Journal of international medical research 20050101

Identification of enzymes involved in phase I metabolism of ciclesonide by human liver microsomes.

European journal of drug metabolism and pharmacokinetics 20050101

Ghrelin degradation by serum and tissue homogenates: identification of the cleavage sites.

Endocrinology 20041101

Zn(II) coordination to polyamine macrocycles containing dipyridine units. New insights into the activity of dinuclear Zn(II) complexes in phosphate ester hydrolysis.

Inorganic chemistry 20041004

Identification of the cytosolic carboxylesterase catalyzing the 5'-deoxy-5-fluorocytidine formation from capecitabine in human liver.

Drug metabolism and disposition: the biological fate of chemicals 20041001

Toward the development of metal-free synthetic nucleases: cleavage of a model substrates by 1,4-diazabicyclo[2.2.2]octane derivatives.

Nucleosides, nucleotides & nucleic acids 20041001

Identification of metal binding residues for the binuclear zinc phosphodiesterase reveals identical coordination as glyoxalase II.

Biochemistry 20040817

Nucleophilic reaction by carbonic anhydrase model zinc compound: characterization of intermediates for CO2 hydration and phosphoester hydrolysis.

Journal of inorganic biochemistry 20040801

Structural and functional characterization of a novel phosphodiesterase from Methanococcus jannaschii.

The Journal of biological chemistry 20040723

Correlation of structure and function in oligonuclear zinc(II) model phosphatases.

Inorganic chemistry 20040712

Differential response of human ovarian cancer cells to induction of apoptosis by vitamin E Succinate and vitamin E analogue, alpha-TEA.

Cancer research 20040615

In vitro and in vivo trans-esterification of 1-[2(R)-(2-amino-2-methylpropionylamino)-3-(1H-indol-3-yl)propionyl]-3(S)-benzyl-piperidine-3-carboxylic acid ethyl ester and the effects of ethanol on its pharmacokinetics in rats.

Pharmaceutical research 20040601

Metallomicellar catalysis: accelerated hydrolysis of BNPP by copper(II), zinc(II), and nickel(II) complexes of long alkanol-imidazole in CTAB micellar solution.

Journal of colloid and interface science 20040515

Evidence for the involvement of a pulmonary first-pass effect via carboxylesterase in the disposition of a propranolol ester derivative after intravenous administration.

The Journal of pharmacology and experimental therapeutics 20031201

Geometry-dependent phosphodiester hydrolysis catalyzed by binuclear copper complexes.

Inorganic chemistry 20031201

Pharmacokinetics and metabolism of NO-1886, a lipoprotein lipase-promoting agent, in cynomolgus monkey.

Xenobiotica; the fate of foreign compounds in biological systems 20031201

Coordination properties of new bis(1,4,7-triazacyclononane) ligands: a highly active dizinc complex in phosphate diester hydrolysis.

Inorganic chemistry 20031020

Vinyl acetate decreases intracellular pH in rat nasal epithelial cells.

Toxicological sciences : an official journal of the Society of Toxicology 20031001

5'-Phosphodiesterase (5'-PDE) from germinated barley for hydrolysis of RNA to produce flavour nucleotides.

Bioresource technology 20030701

Deacylation of N-arylformamides and N-arylacetamides by formamidase in rat liver.

Drug metabolism and disposition: the biological fate of chemicals 20021201

Pyrazolylcyclotriphosphazene containing pendant polymers: synthesis, characterization, and phosphate ester hydrolysis using a Cu(II)-metalated cross-linked polymeric catalyst.

Inorganic chemistry 20021007

Hydrolysis of natural and artificial phosphoesters using zinc model compound with a histidine-containing pseudopeptide.

Journal of inorganic biochemistry 20020830

ElaC encodes a novel binuclear zinc phosphodiesterase.

The Journal of biological chemistry 20020809

Sensory nerve-mediated nasal vasodilatory response to inspired ethyl acrylate.

Inhalation toxicology 20020601

Vinyl acetate-induced intracellular acidification: implications for risk assessment.

Toxicological sciences : an official journal of the Society of Toxicology 20020401

Triisopropyltriazacyclononane copper(II): an efficient phosphodiester hydrolysis catalyst and DNA cleavage agent.

Inorganic chemistry 20020225

In vitro efficacies of phosphorolytic enzymes synthesized in mycelial cells of Aspergillus niger AbZ4 grown by a liquid surface fermentation.

Journal of agricultural and food chemistry 20020213

Concerning two-metal cooperativity in model phosphate hydrolysis.

Bioorganic chemistry 20011201

Concentration-dependent effects of the esterase inhibitor BNPP on macrophage migration and myelin phagocytosis.

Brain research 20011019

Copper(II) complexes of novel N-alkylated derivatives of cis,cis-1,3,5-triaminocyclohexane. 2. Metal-promoted phosphate diester hydrolysis.

Inorganic chemistry 20010813

Phosphodiester hydrolysis by lanthanide complexes of bis-tris propane.

Inorganic chemistry 20010716

La(3+)-catalyzed methanolysis of phosphate diesters. Remarkable rate acceleration of the methanolysis of diphenyl phosphate, methyl p-nitrophenyl phosphate, and bis(p-nitrophenyl) phosphate.

Inorganic chemistry 20010702

Functional interrelationships in the alkaline phosphatase superfamily: phosphodiesterase activity of Escherichia coli alkaline phosphatase.

Biochemistry 20010515

Methyl methacrylate toxicity in rat nasal epithelium: studies of the mechanism of action and comparisons between species.

Toxicology 20010214

Comparison of salt effects on the reactions of acetylcholinesterase with cationic and anionic inhibitors.

Biochimica et biophysica acta 20010112

Evidence against deacetylation and for cytochrome P450-mediated activation in acetaminophen-induced nephrotoxicity in the CD-1 mouse.

Toxicology and applied pharmacology 19910101

The effect of haloalkene cysteine conjugates on rat renal glutathione reductase and lipoyl dehydrogenase activities.

Toxicology and applied pharmacology 19900601

The role of p-aminophenol in acetaminophen-induced nephrotoxicity: effect of bis(p-nitrophenyl) phosphate on acetaminophen and p-aminophenol nephrotoxicity and metabolism in Fischer 344 rats.

Toxicology and applied pharmacology 19851201