(6R,7R)-3-[(acetyloxy)methyl]-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
| Title | Journal |
|---|---|
| A systematic toxicity evaluation of cephalosporins via transcriptomics in zebrafish and in silico ADMET studies. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20180601 |
| Cardiac safety evaluation in zebrafish and in silico ADME prediction of cephalosporins with an aminothiazoyl ring at the C-7 position. | Toxicology and applied pharmacology 20180515 |
| Cefsulodin Inspired Potent and Selective Inhibitors of mPTPB, a Virulent Phosphatase from Mycobacterium tuberculosis. | ACS medicinal chemistry letters 20151210 |
| Gene expressions changes in bronchial epithelial cells: markers for respiratory sensitizers and exploration of the NRF2 pathway. | Toxicology in vitro : an international journal published in association with BIBRA 20140301 |
| Double knockout of β-lactamase and cephalosporin acetyl esterase genes from Escherichia coli reduces cephalosporin C decomposition. | Journal of bioscience and bioengineering 20120601 |
| Struvite precipitation for ammonia nitrogen removal in 7-aminocephalosporanic acid wastewater. | Molecules (Basel, Switzerland) 20120221 |
| Synthesis and preliminary antimicrobial activities of new arylideneamino-1,3,4-thiadiazole-(thio/dithio)-acetamido cephalosporanic acids. | Molecules (Basel, Switzerland) 20120119 |
| Overexpression of synthesized cephalosporin C acylase containing mutations in the substrate transport tunnel. | Journal of bioscience and bioengineering 20120101 |
| A catalytic mechanism for cysteine N-terminal nucleophile hydrolases, as revealed by free energy simulations. | PloS one 20120101 |
| Dual-lifetime referencing (DLR): a powerful method for on-line measurement of internal pH in carrier-bound immobilized biocatalysts. | BMC biotechnology 20120101 |
| Occupational asthma: new low-molecular-weight causal agents, 2000-2010. | Journal of allergy 20120101 |
| Characteristic features and biotechnological applications of cross-linked enzyme aggregates (CLEAs). | Applied microbiology and biotechnology 20111101 |
| [Research progress on strain improvement of Acremonium chrysogenum by genetic engineering]. | Yi chuan = Hereditas 20111001 |
| New implications on genomic adaptation derived from the Helicobacter pylori genome comparison. | PloS one 20110101 |
| Inhibition of Recombinant D-Amino Acid Oxidase from Trigonopsis variabilis by Salts. | Enzyme research 20110101 |
| [Expression of modified oxidase of D-aminoacids of Trigonopsis variabilis in methylotrophic yeasts Pichia pastoris]. | Prikladnaia biokhimiia i mikrobiologiia 20110101 |
| Substitute technology for reference substances in the analysis of impurities in cefonicid for injection with HPLC using a diode array detector. | Journal of AOAC International 20110101 |
| Occupational asthma in antibiotic manufacturing workers: case reports and systematic review. | Journal of allergy 20110101 |
| [Synthesis and characterization of some new rutin and 7-aminocephalosporanic acid derivatives]. | Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20110101 |
| Environmentally safe production of 7-ACA by recombinant Acremonium chrysogenum. | Current microbiology 20101201 |
| Occupational asthma in Korea. | Journal of Korean medical science 20101201 |
| Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. | Bioorganic & medicinal chemistry letters 20101101 |
| Biosynthesis of cephalosporin-C acylase enzyme: optimal media design, purification, and characterization. | Artificial cells, blood substitutes, and immobilization biotechnology 20101001 |
| Enhancement of glutaryl-7-aminocephalosporanic acid acylase activity of gamma-glutamyltranspeptidase of Bacillus subtilis. | Biotechnology journal 20100801 |
| A single Phe54Tyr substitution improves the catalytic activity and thermostability of Trigonopsis variabilis D-amino acid oxidase. | New biotechnology 20100227 |
| Improved cross-linked enzyme aggregates for the production of desacetyl beta-lactam antibiotics intermediates. | Bioresource technology 20100101 |
| Stepwise engineering of a Pichia pastoris D-amino acid oxidase whole cell catalyst. | Microbial cell factories 20100101 |
| Protein engineering of penicillin acylase. | Acta naturae 20100101 |
| Optimization of glutaryl-7-aminocephalosporanic acid acylase expression in E. coli. | Protein expression and purification 20081001 |
| YesT: a new rhamnogalacturonan acetyl esterase from Bacillus subtilis. | Proteins 20080401 |
| Development of the semi-synthetic penicillins and cephalosporins. | International journal of antimicrobial agents 20080301 |
| Properties and applications of microbial D-amino acid oxidases: current state and perspectives. | Applied microbiology and biotechnology 20080201 |
| The stabilizing effects of immobilization in D-amino acid oxidase from Trigonopsis variabilis. | BMC biotechnology 20080101 |
| Enzymatic synthesis of cephalosporins. The immobilized acylase from Arthrobacter viscosus: a new useful biocatalyst. | Applied microbiology and biotechnology 20071201 |
| A colorimetric assay for the determination of acetyl xylan esterase or cephalosporin C acetyl esterase activities using 7-amino cephalosporanic acid, cephalosporin C, or acetylated xylan as substrate. | Analytical biochemistry 20071015 |
| [7-aminocephalosporanic acid induced bronchial asthma in two patients]. | Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 20071001 |
| Site-specific protonation microequilibria of penicillin and cephalosporin beta-lactam core molecules. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20070901 |
| Construction of recombinant Escherichia coli D11/pMSTO and its use in enzymatic preparation of 7-aminocephalosporanic acid in one pot. | Journal of biotechnology 20070501 |
| Reusability of entrapped cells of Pseudomonas diminuta for production of 7-aminocephalosporanic acid. | Applied biochemistry and biotechnology 20070401 |
| Microbial production of 7-amino-cephalosporanic acid and new generation cephalosporins (cephalothin) by different processing strategies. | Artificial cells, blood substitutes, and immobilization biotechnology 20070101 |
| New active site oriented glyoxyl-agarose derivatives of Escherichia coli penicillin G acylase. | BMC biotechnology 20070101 |
| [Microspeciation of amphoteric molecules of unusual acid-base properties]. | Acta pharmaceutica Hungarica 20070101 |
| Thermal inactivation of D-amino acid oxidase from Trigonopsis variabilis occurs via three parallel paths of irreversible denaturation. | Biotechnology and bioengineering 20060705 |
| Spectrophotometric assay for quantitative determination of 7-aminocephalosporanic acid from direct hydrolysis of cephalosporin C. | Analytical biochemistry 20060315 |
| Enzymatic modifications of cephalosporins by cephalosporin acylase and other enzymes. | Critical reviews in biotechnology 20060101 |
| Evolution of an acylase active on cephalosporin C. | Protein science : a publication of the Protein Society 20051201 |
| Purification and characterization of a novel aminoacylase from Streptomyces mobaraensis. | Bioscience, biotechnology, and biochemistry 20051001 |
| Single-step conversion of cephalosporin-C to 7-aminocephalosporanic acid by free and immobilized cells of Pseudomonas diminuta. | Applied biochemistry and biotechnology 20050701 |
| Reactions of pyrazolylborate-zinc-hydroxide complexes related to beta-lactamase activity. | Inorganic chemistry 20050613 |
| 1H and 13 C spectral assignments of 7beta-(cinnamoyl-substituted)amino-3-acetoxymethyl-cephalosporins. | Magnetic resonance in chemistry : MRC 20050301 |
| Interaction of 31 beta-lactam antibiotics with the H+/peptide symporter PEPT2: analysis of affinity constants and comparison with PEPT1. | European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20050101 |
| D-Amino acid oxidase: structure, catalytic mechanism, and practical application. | Biochemistry. Biokhimiia 20050101 |
| Toward the development of a cephalosporin-based dual-release prodrug for use in ADEPT. | The Journal of organic chemistry 20041112 |
| Batch production of deacetyl 7-aminocephalosporanic acid by immobilized cephalosporin-C deacetylase. | Applied microbiology and biotechnology 20040801 |
| [Compared D-amino acid oxidase expression in different Pichia pastoris host strains]. | Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20040701 |
| Modifying the substrate specificity of penicillin G acylase to cephalosporin acylase by mutating active-site residues. | Biochemical and biophysical research communications 20040625 |
| Construction and application of fusion proteins of D-amino acid oxidase and glutaryl-7-aminocephalosporanic acid acylase for direct bioconversion of cephalosporin C to 7-aminocephalosporanic acid. | Biotechnology letters 20040601 |
| Occupational asthma and IgE sensitization to 7-aminocephalosporanic acid. | The Journal of allergy and clinical immunology 20040401 |
| Affinity labeled glutaryl-7-amino cephalosporanic acid acylase C130 can hydrolyze the inhibitor during crystallization. | Biochemical and biophysical research communications 20040116 |
| Synthesis and preliminary antimicrobial evaluation of new 7-(N-pyrrolyl) derivatives of cephalosporins. | Arzneimittel-Forschung 20040101 |
| Catalytic properties of D-amino acid oxidase in cephalosporin C bioconversion: a comparison between proteins from different sources. | Biotechnology progress 20040101 |
| Industrial enzymatic production of cephalosporin-based beta-lactams. | Advances in biochemical engineering/biotechnology 20040101 |
| Deacylation activity of cephalosporin acylase to cephalosporin C is improved by changing the side-chain conformations of active-site residues. | Biochemical and biophysical research communications 20031010 |
| Multivariate analysis and classification of the chemical quality of 7-aminocephalosporanic acid using near-infrared reflectance spectroscopy. | Analytical chemistry 20030715 |
| A rapid and specific method to screen environmental microorganisms for cephalosporin acylase activity. | Journal of microbiological methods 20030701 |
| Industrial production of beta-lactam antibiotics. | Applied microbiology and biotechnology 20030601 |
| An alternative procedure for preparation of cefdinir. | Farmaco (Societa chimica italiana : 1989) 20030601 |
| The kinetic properties of the carboxy terminal domain of the Bacillus licheniformis 749/I BlaR penicillin-receptor shed a new light on the derepression of beta-lactamase synthesis. | Molecular microbiology 20030601 |
| An improved method for preparation of cefpodoxime proxetil. | Farmaco (Societa chimica italiana : 1989) 20030501 |
| Immobilization of glutaryl-7-aminocephalosporanic acid acylase on silica gel and enhancement of its stability. | Applied biochemistry and biotechnology 20030301 |
| Cross-reactivity of cefotetan and ceftriaxone antibodies, associated with hemolytic anemia, with other: cephalosporins and penicillin. | American journal of clinical pathology 20020801 |
| Expression of gene encoding GL-7ACA acylase in Escherichia coli. | Sheng wu hua xue yu sheng wu wu li xue bao Acta biochimica et biophysica Sinica 20020701 |
| The crystal structure of Helicobacter pylori cysteine-rich protein B reveals a novel fold for a penicillin-binding protein. | The Journal of biological chemistry 20020322 |
| Structure-based prediction of modifications in glutarylamidase to allow single-step enzymatic production of 7-aminocephalosporanic acid from cephalosporin C. | Protein science : a publication of the Protein Society 20020101 |
| Active site residues of cephalosporin acylase are critical not only for enzymatic catalysis but also for post-translational modification. | The Journal of biological chemistry 20011221 |
| Structure of cephalosporin acylase in complex with glutaryl-7-aminocephalosporanic acid and glutarate: insight into the basis of its substrate specificity. | Chemistry & biology 20011201 |
| [Establishment of detective systems for GL-7ACA acylase expression]. | Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20011101 |
| Modulation of penicillin acylase properties via immobilization techniques: one-pot chemoenzymatic synthesis of Cephamandole from Cephalosporin C. | Bioorganic & medicinal chemistry letters 20010917 |
| Improvement of the synthesis of diphenylmethyl 7beta-(o-hydroxy)benzylideneamino-3-hydroxymethyl-3-cephem-4-carboxylate. | Farmaco (Societa chimica italiana : 1989) 20010801 |
| D-amino-acid oxidase--an improved production of the enzyme by the yeast Trigonopsis variabilis in a laboratory fermentor. | Folia microbiologica 20010101 |
| Epitope analysis of aztreonam by antiaztreonam monoclonal antibodies and possible consequences in beta-lactams hypersensitivity. | International archives of allergy and immunology 19920101 |
| [Thoughts on explaining cigarette smoking]. | Das Offentliche Gesundheitswesen 19870201 |