Home Halogens 5,7-Dichloroquinolin-8-ol

5,7-Dichloroquinolin-8-ol

CAS No.:
773-76-2
Catalog Number:
AG003MAN
Molecular Formula:
C9H5Cl2NO
Molecular Weight:
214.0481
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1g
98%(HPLC)
In Stock USA
United States
$48
- +
5g
98%(HPLC)
In Stock USA
United States
$105
- +
25g
98%(HPLC)
In Stock USA
United States
$251
- +
Product Description
Catalog Number:
AG003MAN
Chemical Name:
5,7-Dichloroquinolin-8-ol
CAS Number:
773-76-2
Molecular Formula:
C9H5Cl2NO
Molecular Weight:
214.0481
MDL Number:
MFCD00006786
IUPAC Name:
5,7-dichloroquinolin-8-ol
InChI:
InChI=1S/C9H5Cl2NO/c10-6-4-7(11)9(13)8-5(6)2-1-3-12-8/h1-4,13H
InChI Key:
WDFKMLRRRCGAKS-UHFFFAOYSA-N
SMILES:
Clc1cc(Cl)c2c(c1O)nccc2
EC Number:
212-258-3
UNII:
2I8BD50I8B
Properties
Complexity:
191  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
212.975g/mol
Formal Charge:
0
Heavy Atom Count:
13  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
214.045g/mol
Monoisotopic Mass:
212.975g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
33.1A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
3.5  
Literature
Title Journal
Fragment-based discovery of 8-hydroxyquinoline inhibitors of the HIV-1 integrase-lens epithelium-derived growth factor/p75 (IN-LEDGF/p75) interaction. Journal of medicinal chemistry 20130328
Synthesis and characterization of 8-hydroxyquinoline complexes of tin(IV) and their application in organic light emitting diode. Journal of fluorescence 20120901
Discovery of potent and selective inhibitors of human platelet-type 12- lipoxygenase. Journal of medicinal chemistry 20110811
Combinations of antibiotics and nonantibiotic drugs enhance antimicrobial efficacy. Nature chemical biology 20110601
High cytotoxicity of dihalo-substituted 8-quinolinolato-lanthanides. Dalton transactions (Cambridge, England : 2003) 20110227
8-Hy-droxy-2-methyl-quinolinium tetra-chlorido(quinolin-2-olato-κN,O)stannate(IV) methanol disolvate. Acta crystallographica. Section E, Structure reports online 20110201
Synthesis and characterization of nano-pore thallium (III) ion-imprinted polymer as a new sorbent for separation and preconcentration of thallium. Journal of hazardous materials 20110115
Identification of clinically used drugs that activate pregnane X receptors. Drug metabolism and disposition: the biological fate of chemicals 20110101
Antifungal testing and high-throughput screening of compound library against Geomyces destructans, the etiologic agent of geomycosis (WNS) in bats. PloS one 20110101
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. Bioorganic & medicinal chemistry letters 20101101
N,N-Dicyclo-hexyl-2-(5,7-dichloro-8-quinol-yloxy)acetamide. Acta crystallographica. Section E, Structure reports online 20091101
5,7-Dichloro-quinolin-8-ol. Acta crystallographica. Section E, Structure reports online 20090501
Synthesis of nano-pore samarium (III)-imprinted polymer for preconcentrative separation of samarium ions from other lanthanide ions via solid phase extraction. Analytica chimica acta 20080808
Differential modulation of Alzheimer's disease amyloid beta-peptide accumulation by diverse classes of metal ligands. The Biochemical journal 20071101
Investigation of the role of chelating ligand in the synthesis of ion-imprinted polymeric resins on the selective enrichment of uranium(VI). Analytica chimica acta 20070328
Ion imprinted polymer particles for separation of yttrium from selected lanthanides. Journal of separation science 20060601
Microsphere-based protease assays and screening application for lethal factor and factor Xa. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
The evaluation of liposome-water partitioning of 8-hydroxyquinolines and their copper complexes. Environmental science & technology 20060315
Prediction of genotoxicity of chemical compounds by statistical learning methods. Chemical research in toxicology 20050601
Solid phase extraction preconcentration of cobalt and nickel with 5,7-dichloroquinone-8-ol embedded styrene-ethylene glycol dimethacrylate polymer particles and determination by flame atomic absorption spectrometry (FAAS). Talanta 20050415
Selective recognition of neodymium (III) using ion imprinted polymer particles. Journal of molecular recognition : JMR 20050101
Clioquinol and pyrrolidine dithiocarbamate complex with copper to form proteasome inhibitors and apoptosis inducers in human breast cancer cells. Breast cancer research : BCR 20050101
A monooxygenase catalyzes sequential dechlorinations of 2,4,6-trichlorophenol by oxidative and hydrolytic reactions. The Journal of biological chemistry 20040220
Solid phase extractive preconcentration of thorium onto 5,7-dichloroquinoline-8-ol modified benzophenone. Talanta 20021016
Structure-activity studies in E. coli strains on ochratoxin A (OTA) and its analogues implicate a genotoxic free radical and a cytotoxic thiol derivative as reactive metabolites. Mutation research 19940501
Genotoxicity of ochratoxin A and structurally related compounds in Escherichia coli strains: studies on their mode of action. IARC scientific publications 19910101
Properties