5,6-Dihydro-5-methyluracil
Title | Journal |
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Revealing the metabonomic variation of EC using ¹H-NMR spectroscopy and its association with the clinicopathological characteristics. | Molecular biology reports 20120901 |
Biochemical mapping of human NEIL1 DNA glycosylase and AP lyase activities. | DNA repair 20120901 |
Yield of single- and double-strand breaks and nucleobase lesions in fully hydrated plasmid DNA films irradiated with high-LET charged particles. | Radiation research 20120501 |
Pharmacokinetics of orally administered uracil in healthy volunteers and in DPD-deficient patients, a possible tool for screening of DPD deficiency. | Cancer chemotherapy and pharmacology 20111201 |
Delayed repair of radiation induced clustered DNA damage: friend or foe? | Mutation research 20110603 |
Unexpected role for Helicobacter pylori DNA polymerase I as a source of genetic variability. | PLoS genetics 20110601 |
DNA damage induced by low-energy electrons: conversion of thymine to 5,6-dihydrothymine in the oligonucleotide trimer TpTpT. | Radiation research 20110201 |
New insights in the removal of the hydantoins, oxidation product of pyrimidines, via the base excision and nucleotide incision repair pathways. | PloS one 20110101 |
Severe encephalopathy, lactic acidosis, vegetative instability and neuropathy with 5-Fluorouracil treatment - pyrimidine degradation defect or beriberi? | Case reports in oncology 20110101 |
Predicting biological functions of compounds based on chemical-chemical interactions. | PloS one 20110101 |
Sequence dependence of excess electron transfer in DNA. | The journal of physical chemistry. B 20101118 |
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. | Bioorganic & medicinal chemistry letters 20101101 |
Photoinduced ring opening reactions and subsequent thermal ring closure reactions in the thymine-ammonia system and related systems. | Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20100924 |
Saccharomyces cerevisiae-based system for studying clustered DNA damages. | Radiation and environmental biophysics 20100801 |
DNA repair by photolyase: a novel substrate with low background absorption around 265 nm for transient absorption studies in the UV. | Biochemistry 20100119 |
Dihydropyrimidinase deficiency: Phenotype, genotype and structural consequences in 17 patients. | Biochimica et biophysica acta 20100101 |
Molecular mechanisms of ultraviolet radiation-induced DNA damage and repair. | Journal of nucleic acids 20100101 |
5,6-Dihydrothymine impairs the base excision repair pathway of a closely opposed AP site or single-strand break. | Radiation research 20091101 |
Biological consequences of potential repair intermediates of clustered base damage site in Escherichia coli. | Mutation research 20091002 |
A functional analysis of the pyrimidine catabolic pathway in Arabidopsis. | The New phytologist 20090701 |
Catalytically impaired hMYH and NEIL1 mutant proteins identified in patients with primary sclerosing cholangitis and cholangiocarcinoma. | Carcinogenesis 20090701 |
Processing of thymine glycol in a clustered DNA damage site: mutagenic or cytotoxic. | Nucleic acids research 20090701 |
Metal-triggered changes in the stability and secondary structure of a tetrameric dihydropyrimidinase: a biophysical characterization. | Biophysical chemistry 20090101 |
Fluorescence detection of the endonuclease III reaction using modified oligonucleotides. | Nucleic acids symposium series (2004) 20090101 |
Interconversion of the cis-5R,6S- and trans-5R,6R-thymine glycol lesions in duplex DNA. | Journal of the American Chemical Society 20080903 |
Study of interaction of XRCC1 with DNA and proteins of base excision repair by photoaffinity labeling technique. | Biochemistry. Biokhimiia 20070801 |
Clinical, biochemical and genetic findings in two siblings with a dihydropyrimidinase deficiency. | Molecular genetics and metabolism 20070601 |
Use of damaged DNA and dNTP substrates by the error-prone DNA polymerase X from African swine fever virus. | Biochemistry 20070327 |
HPLC-electrospray tandem mass spectrometry for rapid determination of dihydropyrimidine dehydrogenase activity. | Clinical chemistry 20070301 |
Vibrational spectra and structure of 5,6-diamino uracil and 5,6-dihydro-5-methyl uracil by density functional theory calculations. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20070201 |
Crystallization and preliminary crystallographic studies of the recombinant dihydropyrimidinase from Sinorhizobium meliloti CECT4114. | Acta crystallographica. Section F, Structural biology and crystallization communications 20061201 |
Contributions of an endonuclease IV homologue to DNA repair in the African swine fever virus. | Biochemistry 20060307 |
Purification, crystallization and X-ray diffraction analysis of dihydropyrimidinase from Dictyostelium discoideum. | Acta crystallographica. Section F, Structural biology and crystallization communications 20060101 |
The roles of specific glycosylases in determining the mutagenic consequences of clustered DNA base damage. | Nucleic acids research 20060101 |
XRCC1 interactions with multiple DNA glycosylases: a model for its recruitment to base excision repair. | DNA repair 20050712 |
Crystallization and X-ray diffraction analysis of dihydropyrimidinase from Saccharomyces kluyveri. | Acta crystallographica. Section F, Structural biology and crystallization communications 20050401 |
Gamma-radiolysis DNA products: synthesis of 6-(alpha-thyminyl)-5,6-dihydro-4-thiothymine derivatives. | The Journal of organic chemistry 20040709 |
Dihydrothymine lesion in X-irradiated DNA: characterization at the molecular level and detection in cells. | International journal of radiation biology 20040501 |
Qualitative and quantitative analyses of the decomposition products that arise from the exposure of thymine to monochromatic ultrasoft X rays and 60Co gamma rays in the solid state. | Radiation research 20040401 |
Identification and characterization of an intermediate in the alkali degradation of (6-4) photoproduct-containing DNA. | The Journal of biological chemistry 20031219 |
Rapid gas chromatographic-mass spectrometric diagnosis of dihydropyrimidine dehydrogenase deficiency and dihydropyrimidinase deficiency. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030715 |
Sensitive method for the quantification of urinary pyrimidine metabolites in healthy adults by gas chromatography-tandem mass spectrometry. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030705 |
Acyclic nucleoside analogues as novel inhibitors of human mitochondrial thymidine kinase. | Journal of medicinal chemistry 20020912 |
Screening and diagnosis of beta-ureidopropionase deficiency by gas chromatographic/mass spectrometric analysis of urine. | Journal of mass spectrometry : JMS 20020901 |
Development and characterization of a monoclonal antibody with cross-reactivity towards uracil and thymine, and its potential use in screening patients treated with 5-fluorouracil for possible risks. | Clinica chimica acta; international journal of clinical chemistry 20020801 |
Efficiency of incision of an AP site within clustered DNA damage by the major human AP endonuclease. | Biochemistry 20020115 |
Alternative nucleotide incision repair pathway for oxidative DNA damage. | Nature 20020110 |
Repair of oxidized purines and damaged pyrimidines by E. coli Fpg protein: different roles of proline 2 and lysine 57 residues. | Environmental and molecular mutagenesis 20020101 |
Efficiency of excision of 8-oxo-guanine within DNA clustered damage by XRS5 nuclear extracts and purified human OGG1 protein. | Biochemistry 20011002 |
Simple gas chromatographic-mass spectrometric procedure for diagnosing pyrimidine degradation defects for prevention of severe anticancer side effects. | Journal of chromatography. B, Biomedical sciences and applications 20010705 |
Recognition and kinetics for excision of a base lesion within clustered DNA damage by the Escherichia coli proteins Fpg and Nth. | Biochemistry 20010515 |
DNA substrates containing defined oxidative base lesions and their application to study substrate specificities of base excision repair enzymes. | Progress in nucleic acid research and molecular biology 20010101 |
Processing of DNA base damage by DNA polymerases. Dihydrothymine and beta-ureidoisobutyric acid as models for instructive and noninstructive lesions. | The Journal of biological chemistry 19910125 |
Synthesis of DNA fragments containing 5,6-dihydrothymine, a major product of thymine gamma radiolysis. | Nucleic acids research 19880111 |