Home Other Building Blocks 5,6,7-Trimethoxy-2-phenyl-4H-chromen-4-one

5,6,7-Trimethoxy-2-phenyl-4H-chromen-4-one

CAS No.:
973-67-1
Catalog Number:
AG003M9D
Molecular Formula:
C18H16O5
Molecular Weight:
312.3166
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Product Description
Catalog Number:
AG003M9D
Chemical Name:
5,6,7-Trimethoxy-2-phenyl-4H-chromen-4-one
CAS Number:
973-67-1
Molecular Formula:
C18H16O5
Molecular Weight:
312.3166
MDL Number:
MFCD00017457
IUPAC Name:
5,6,7-trimethoxy-2-phenylchromen-4-one
InChI:
InChI=1S/C18H16O5/c1-20-15-10-14-16(18(22-3)17(15)21-2)12(19)9-13(23-14)11-7-5-4-6-8-11/h4-10H,1-3H3
InChI Key:
HJNJAUYFFFOFBW-UHFFFAOYSA-N
SMILES:
COc1cc2oc(cc(=O)c2c(c1OC)OC)c1ccccc1
Properties
Complexity:
454  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
312.1g/mol
Formal Charge:
0
Heavy Atom Count:
23  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
312.321g/mol
Monoisotopic Mass:
312.1g/mol
Rotatable Bond Count:
4  
Topological Polar Surface Area:
54A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
3.1  
Literature
Title Journal
5,6,7-trimethoxyflavone suppresses pro-inflammatory mediators in lipopolysaccharide-induced RAW 264.7 macrophages and protects mice from lethal endotoxin shock. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20131201
4'-bromo-5,6,7-trimethoxyflavone represses lipopolysaccharide-induced iNOS and COX-2 expressions by suppressing the NF-κB signaling pathway in RAW 264.7 macrophages. Bioorganic & medicinal chemistry letters 20120101
The first bis-retrochalcone from Fissistigma latifolium. Planta medica 20111201
Studies on the antimicrobial activity and brine shrimp toxicity of Zeyheria tuberculosa (Vell.) Bur. (Bignoniaceae) extracts and their main constituents. Annals of clinical microbiology and antimicrobials 20090101
Antimetastatic potentials of flavones on oral cancer cell via an inhibition of matrix-degrading proteases. Archives of oral biology 20080301
Antiherpevirus activity of Artemisia arborescens essential oil and inhibition of lateral diffusion in Vero cells. Annals of clinical microbiology and antimicrobials 20070101
Virucidal agents in the eve of manorapid synergy. GMS Krankenhaushygiene interdisziplinar 20070101
Synthesis and in vitro study of novel 7-O-acyl derivatives of Oroxylin A as antibacterial agents. Bioorganic & medicinal chemistry letters 20050901
Increased anti-P-glycoprotein activity of baicalein by alkylation on the A ring. Journal of medicinal chemistry 20041021
Fatty acid synthase inhibitors from plants: isolation, structure elucidation, and SAR studies. Journal of natural products 20021201
Antiviral activity of 5,6,7-trimethoxyflavone and its potentiation of the antiherpes activity of acyclovir. The Journal of antimicrobial chemotherapy 19970601
Properties