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Piperidin-4-one

CAS No.:
41661-47-6
Catalog Number:
AG003LZT
Molecular Formula:
C5H9NO
Molecular Weight:
99.1311
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Product Description
Catalog Number:
AG003LZT
Chemical Name:
Piperidin-4-one
CAS Number:
41661-47-6
Molecular Formula:
C5H9NO
Molecular Weight:
99.1311
IUPAC Name:
piperidin-4-one
InChI:
InChI=1S/C5H9NO/c7-5-1-3-6-4-2-5/h6H,1-4H2
InChI Key:
VRJHQPZVIGNGMX-UHFFFAOYSA-N
SMILES:
O=C1CCNCC1
EC Number:
255-481-1
UNII:
15WP1EA7UH
Properties
Complexity:
72.1  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
99.068g/mol
Formal Charge:
0
Heavy Atom Count:
7  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
99.133g/mol
Monoisotopic Mass:
99.068g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
29.1A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-0.7  
Literature
Title Journal
5-(4-Fluoro-benzyl-idene)-4'-(4-fluoro-phen-yl)-1,1'-dimethyl-dispiro-[piperidine-3,3'-pyrrolidine-2',3''-indoline]-4,2''-dione. Acta crystallographica. Section E, Structure reports online 20121001
Ultrasound-promoted synthesis of novel bipodal and tripodalpiperidin-4-ones and silica chloride mediated conversion to its piperidin-4-ols: synthesis and structural confinements. Ultrasonics sonochemistry 20120501
(3E,5E)-3,5-Bis(naphthalen-1-yl-methyl-idene)piperidin-4-one. Acta crystallographica. Section E, Structure reports online 20120301
1-Formyl-c-3,t-3-dimethyl-r-2,c-6-di-phenyl-piperidin-4-one. Acta crystallographica. Section E, Structure reports online 20120301
2,6-Bis(4-meth-oxy-phen-yl)-1,3-dimethyl-piperidin-4-one O-benzyl-oxime. Acta crystallographica. Section E, Structure reports online 20120201
2,6-Bis(4-chloro-phen-yl)-1,3-dimethyl-piperidin-4-one O-benzyl-oxime. Acta crystallographica. Section E, Structure reports online 20120201
2,2,6,6-Tetra-methyl-4-oxopiperidin-1-ium 4-chloro-3-nitro-benzoate. Acta crystallographica. Section E, Structure reports online 20110801
Ethyl 1-[2-(1H-benzotriazol-1-yl)acet-yl]-4-hy-droxy-2,6-diphenyl-1,2,5,6-tetra-hydro-pyridine-3-carboxyl-ate. Acta crystallographica. Section E, Structure reports online 20110701
3-Nitroso-2,4,6,8-tetra-phenyl-3,7-diaza-bicyclo-[3.3.1]nonan-9-one. Acta crystallographica. Section E, Structure reports online 20110701
Silver-catalyzed cycloisomerization of 1,n-allenynamides. Organic letters 20110603
(3E,5E)-3,5-Dibenzyl-idene-1-[3-(piperidin-1-yl)propano-yl]piperidin-4-one. Acta crystallographica. Section E, Structure reports online 20110601
(3E,5E)-1-Acryloyl-3,5-bis-(2,4-dichloro-benzyl-idene)piperidin-4-one hemihydrate. Acta crystallographica. Section E, Structure reports online 20110601
1-Benzyl-3,5-bis-(4-chloro-benzyl-idene)piperidin-4-one. Acta crystallographica. Section E, Structure reports online 20110601
Synthesis, spectral, crystal structure and in vitro antimicrobial evaluation of imidazole/benzotriazole substituted piperidin-4-one derivatives. European journal of medicinal chemistry 20110501
3,5-Bis(4-chloro-benzyl-idene)-1-methyl-piperidin-4-one. Acta crystallographica. Section E, Structure reports online 20110401
α,β-Unsaturated carbonyl system of chalcone-based derivatives is responsible for broad inhibition of proteasomal activity and preferential killing of human papilloma virus (HPV) positive cervical cancer cells. Journal of medicinal chemistry 20110127
5-[(E)-2-Fluoro-benzyl-idene]-8-(2-fluoro-phen-yl)-2-hy-droxy-10-methyl-3,10-di-aza-hexa-cyclo-[10.7.1.1.0.0.0]henicosa-1(20),12,14,16,18-pentaen-6-one. Acta crystallographica. Section E, Structure reports online 20110101
1-{[5-(4-Chloro-phen-yl)-1-(4-fluoro-phen-yl)-1H-pyrazol-3-yl]carbon-yl]}piperidin-4-one. Acta crystallographica. Section E, Structure reports online 20101201
(E)-N'-(3,3-Dimethyl-2,6-diphenyl-piperidin-4-yl-idene)isonicotinohydrazide. Acta crystallographica. Section E, Structure reports online 20101101
1-Chloro-acetyl-2,6-bis-(2-chloro-phen-yl)-3,5-dimethyl-piperidin-4-one. Acta crystallographica. Section E, Structure reports online 20100901
2-Hy-droxy-11-methyl-16-[(E)-4-methyl-benzyl-idene]-13-(4-methyl-phen-yl)-1,11-diaza-penta-cyclo-[12.3.1.0.0.0]octa-deca-3(8),4,6-triene-9,15-dione. Acta crystallographica. Section E, Structure reports online 20100901
1-{3-[(4-Oxopiperidin-1-yl)carbon-yl]benzoyl}piperidin-4-one. Acta crystallographica. Section E, Structure reports online 20100801
16-[(E)-Benzyl-idene]-2-hy-droxy-12,13-diphenyl-1,11-diaza-penta-cyclo-[12.3.1.0.0.0]octa-deca-3(8),4,6-triene-9,15-dione. Acta crystallographica. Section E, Structure reports online 20100801
2-Hy-droxy-16-[(E)-4-methyl-benzyl-idene]-13-(4-methyl-phen-yl)-12-phenyl-1,11-diaza-penta-cyclo-[12.3.1.0.0.0]octa-deca-3(8),4,6-triene-9,15-dione. Acta crystallographica. Section E, Structure reports online 20100801
1-[2,4,6-Trimethyl-3,5-bis-(4-oxopiperidin-1-ylmeth-yl)benz-yl]piperidin-4-one. Acta crystallographica. Section E, Structure reports online 20100601
Aminodifluorosulfinium salts: selective fluorination reagents with enhanced thermal stability and ease of handling. The Journal of organic chemistry 20100521
Structure-based rational design, synthesis and antifungal activity of oxime-containing azole derivatives. Bioorganic & medicinal chemistry letters 20100501
Synthesis, crystal and antibacterial studies of diversely functionalized tetrahydropyridin-4-ol. Bioorganic & medicinal chemistry letters 20100401
Synthesis of beta-aminoketones and construction of highly substituted 4-piperidones by mannich reaction induced by persistent radical cation salts. Organic letters 20100219
1-Dichloro-acetyl-r-2,c-6-bis-(4-methoxy-phen-yl)-t-3,t-5-dimethyl-piperidin-4-one. Acta crystallographica. Section E, Structure reports online 20100201
1,1'-(p-Phenyl-enedimethyl-ene)dipiperidin-4-one. Acta crystallographica. Section E, Structure reports online 20100101
Synthesis and antimalarial evaluation of some 4-quinazolinone derivatives based on febrifugine. Journal of advanced pharmaceutical technology & research 20100101
2,6-Bis(3-methoxy-phen-yl)-3-methyl-piperidin-4-one. Acta crystallographica. Section E, Structure reports online 20091201
(3E,5E)-3,5-Bis(4-allyl-oxybenzyl-idene)-1-benzyl-piperidin-4-one. Acta crystallographica. Section E, Structure reports online 20091201
(3E,5E)-1-Benzyl-3,5-bis-(2-fluoro-benzyl-idene)piperidin-4-one. Acta crystallographica. Section E, Structure reports online 20091101
(3E,5E)-1-Benzyl-3,5-dibenzyl-idenepiperidin-4-one. Acta crystallographica. Section E, Structure reports online 20091101
1-Formyl-r-2,c-6-bis-(4-methoxy-phen-yl)-t-3-methyl-piperidin-4-one. Acta crystallographica. Section E, Structure reports online 20091101
2,3,6-Triphenyl-piperidin-4-one. Acta crystallographica. Section E, Structure reports online 20091001
1-Benzoyl-3-methyl-2,6-diphenyl-4-piperidone. Acta crystallographica. Section E, Structure reports online 20090701
Design, cytotoxic and fluorescent properties of novel N-phosphorylalkyl substituted E,E-3,5-bis(arylidene)piperid-4-ones. European journal of medicinal chemistry 20090501
[Design, synthesis and antalgic activities of aralkyl-ketone-4-piperidol derivatives]. Yao xue xue bao = Acta pharmaceutica Sinica 20090401
Synthesis and spectral characterization of a new class of N-(N-methylpiperazinoacetyl)-2,6-diarylpiperidin-4-ones: antimicrobial, analgesic and antipyretic studies. European journal of medicinal chemistry 20090201
1,3-Dimethyl-2,6-diphenyl-piperidin-4-one. Acta crystallographica. Section E, Structure reports online 20090201
1-Benzyl-4',5'-diphenyl-piperidine-3-spiro-3'-pyrrolidine-2'-spiro-3''-indoline-4,2''-dione. Acta crystallographica. Section E, Structure reports online 20090101
A facile synthesis, antibacterial, and antitubercular studies of some piperidin-4-one and tetrahydropyridine derivatives. Bioorganic & medicinal chemistry letters 20081215
2,4,6,8-Tetra-kis(4-fluoro-phen-yl)-3,7-diaza-bicyclo-[3.3.1]nonan-9-one. Acta crystallographica. Section E, Structure reports online 20081201
r-2,c-6-Bis(4-fluoro-phen-yl)-t-3,t-5-dimethyl-piperidin-4-one. Acta crystallographica. Section E, Structure reports online 20080201
Superelectrophilic activation of 4-heterocyclohexanones. Implications for polymer synthesis. A theoretical study. The journal of physical chemistry. A 20071227
Oligospiroketals as novel molecular rods. Chemistry (Weinheim an der Bergstrasse, Germany) 20070101
Piperidones with activity against Plasmodium falciparum. Parasitology research 20060801
Synthesis, stereochemistry, and antimicrobial evaluation of substituted piperidin-4-one oxime ethers. European journal of medicinal chemistry 20060601
Highly enantioselective access to primary propargylamines: 4-piperidinone as a convenient protecting group. Organic letters 20060525
Diastereoselective synthesis of some novel benzopyranopyridine derivatives. Beilstein journal of organic chemistry 20060101
Improved heteroatom nucleophilic addition to electron-poor alkenes promoted by CeCl3.7H2O/NaI system supported on alumina in solvent-free conditions. The Journal of organic chemistry 20050107
A straightforward and versatile synthetic approach to 1-azabicyclic alkaloids. The Journal of organic chemistry 20041015
6-Bromomethyl-4H-1,3-dioxin: a versatile bromomethyl vinyl ketone equivalent for heterocycle and carbocycle construction. Journal of the American Chemical Society 20020206
Novel spiropiperidines as highly potent and subtype selective sigma-receptor ligands. Part 1. Journal of medicinal chemistry 20020117
Properties