Dl-mevalonic acid lactone
| Title | Journal |
|---|---|
| Interference in mevalonate pathway ameliorates homocysteine-induced endothelium-dysfunction. | European journal of pharmacology 20121005 |
| Production and characterization of antifungal compounds produced by Lactobacillus plantarum IMAU10014. | PloS one 20120101 |
| Biosynthesis of sesqui- and diterpenes by the gibberellin producer Fusarium fujikuroi. | Chembiochem : a European journal of chemical biology 20111125 |
| Molecular mechanism of vasorelaxant and antiatherogenic effects of the statins in the human saphenous vein graft. | European journal of pharmacology 20110901 |
| Liquid chromatography-tandem mass spectrometry method for the measurement of serum mevalonic acid: a novel marker of hydroxymethylglutaryl coenzyme A reductase inhibition by statins. | Annals of clinical biochemistry 20110501 |
| Mevalonate depletion mediates the suppressive impact of geranylgeraniol on murine B16 melanoma cells. | Experimental biology and medicine (Maywood, N.J.) 20110501 |
| Camphene, a plant-derived monoterpene, reduces plasma cholesterol and triglycerides in hyperlipidemic rats independently of HMG-CoA reductase activity. | PloS one 20110101 |
| An essential farnesylated kinesin in Trypanosoma brucei. | PloS one 20110101 |
| Involvement of oxidative stress in simvastatin-induced apoptosis of murine CT26 colon carcinoma cells. | Toxicology letters 20101215 |
| Cloning and characterization of a novel gene that encodes (S)-beta-bisabolene synthase from ginger, Zingiber officinale. | Planta 20100601 |
| Increasing diterpene yield with a modular metabolic engineering system in E. coli: comparison of MEV and MEP isoprenoid precursor pathway engineering. | Applied microbiology and biotechnology 20100201 |
| Involvement of the phospholipid sterol acyltransferase1 in plant sterol homeostasis and leaf senescence. | Plant physiology 20100101 |
| Functional annotation, genome organization and phylogeny of the grapevine (Vitis vinifera) terpene synthase gene family based on genome assembly, FLcDNA cloning, and enzyme assays. | BMC plant biology 20100101 |
| Synthesis and HMG-CoA reductase inhibition of 2-cyclopropyl-4-thiophenyl-quinoline mevalonolactones. | Bioorganic & medicinal chemistry 20091201 |
| Effects of cholesterol and nuclear hormone receptor agonists on the production of transforming growth factor-beta in macrophages. | Bulletin of experimental biology and medicine 20090901 |
| Complete blockage of the mevalonate pathway results in male gametophyte lethality. | Journal of experimental botany 20090501 |
| Conjugated hyperbilirubinaemia as the first manifestation of mevalonic aciduria in a term newborn. | Neuro endocrinology letters 20090101 |
| Stable carbon isotope discrimination by human 3-hydroxy-3-methylglutaryl-coenzyme A reductase. | Journal of lipid research 20081201 |
| Inhibition of rho family functions by lovastatin promotes myelin repair in ameliorating experimental autoimmune encephalomyelitis. | Molecular pharmacology 20080501 |
| Genetic evidence for the role of isopentenyl diphosphate isomerases in the mevalonate pathway and plant development in Arabidopsis. | Plant & cell physiology 20080401 |
| Statins induce lethal effects in acute myeloblastic leukemia [corrected] cells within 72 hours. | Leukemia & lymphoma 20080201 |
| Determination of key intermediates in cholesterol and bile acid biosynthesis by stable isotope dilution mass spectrometry. | Analytical chemistry insights 20080101 |
| Statins stimulate in vitro membrane FasL expression and lymphocyte apoptosis through RhoA/ROCK pathway in murine melanoma cells. | Neoplasia (New York, N.Y.) 20071201 |
| Protective effects of a squalene synthase inhibitor, lapaquistat acetate (TAK-475), on statin-induced myotoxicity in guinea pigs. | Toxicology and applied pharmacology 20070815 |
| Modulation by simvastatin of iberiotoxin-sensitive, Ca2+-activated K+ channels of porcine coronary artery smooth muscle cells. | British journal of pharmacology 20070801 |
| Highly sensitive assay of HMG-CoA reductase activity by LC-ESI-MS/MS. | Journal of lipid research 20070501 |
| Validation of the LC-MS/MS method for the quantification of mevalonic acid in human plasma and determination of the matrix effect. | Journal of lipid research 20061001 |
| Biosynthesis of mono- and sesquiterpenes in strawberry fruits and foliage: 2H labeling studies. | Journal of agricultural and food chemistry 20060222 |
| Activators of the energy sensing kinase AMPK inhibit random cell movement and chemotaxis in U937 cells. | Immunology and cell biology 20060201 |
| Effect of geraniol on fatty-acid and mevalonate metabolism in the human hepatoma cell line Hep G2. | Biochemistry and cell biology = Biochimie et biologie cellulaire 20060201 |
| Juvenile hormone titer versus juvenile hormone synthesis in female nymphs and adults of the German cockroach, Blattella germanica. | Journal of insect science (Online) 20060101 |
| Prenylation-defective human connexin32 mutants are normally localized and function equivalently to wild-type connexin32 in myelinating Schwann cells. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20050803 |
| 4,8-Dimethyldecanal, the aggregation pheromone of Tribolium castaneum, is biosynthesized through the fatty acid pathway. | Journal of chemical ecology 20050601 |
| Suppression of autoimmune retinal disease by lovastatin does not require Th2 cytokine induction. | Journal of immunology (Baltimore, Md. : 1950) 20050215 |
| Revised chirality of the acyl group of 8'-O-(3-hydroxy-3-methylglutaryl)-8'-hydroxyabscisic acid. | Phytochemistry 20040901 |
| Statins upregulate PCSK9, the gene encoding the proprotein convertase neural apoptosis-regulated convertase-1 implicated in familial hypercholesterolemia. | Arteriosclerosis, thrombosis, and vascular biology 20040801 |
| Cell-based screen of HMG-CoA reductase inhibitors and expression regulators using LC-MS. | Analytical biochemistry 20040601 |
| Calmodulin antagonist W-7 inhibits de novo synthesis of cholesterol and suppresses secretion of de novo synthesized and preformed lipids from cultured hepatocytes. | Biochimica et biophysica acta 20040601 |
| Leukaemia inhibitory factor or oncostatin M induction of Swiss 3T3 cells does not require mevalonic acid synthesis nor protein isoprenylation to initiate DNA replication. | Biochemical and biophysical research communications 20040123 |
| Cholesterol-lowering properties of Ganoderma lucidum in vitro, ex vivo, and in hamsters and minipigs. | Lipids in health and disease 20040101 |
| Methodology for synthesis and isolation of 5-phosphomevalonic acid. | Analytical biochemistry 20031015 |
| Frontalin: De novo biosynthesis of an aggregation pheromone component by Dendroctonus spp. bark beetles (Coleoptera: Scolytidae). | Insect biochemistry and molecular biology 20030801 |
| Lovastatin inhibits brain endothelial cell Rho-mediated lymphocyte migration and attenuates experimental autoimmune encephalomyelitis. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030501 |
| Regulation of isoprenoid/cholesterol biosynthesis in cells from mevalonate kinase-deficient patients. | The Journal of biological chemistry 20030221 |
| Effect of phytosterols on cholesterol metabolism and MAP kinase in MDA-MB-231 human breast cancer cells. | The Journal of nutritional biochemistry 20030201 |
| Biogenetic studies in Syringa vulgaris L.: synthesis and bioconversion of deuterium-labeled precursors into lilac aldehydes and lilac alcohols. | Journal of agricultural and food chemistry 20030115 |
| Anti-proliferative action of endogenous dehydroepiandrosterone metabolites on human cancer cell lines. | Steroids 20030101 |
| Squalene synthase inhibitors suppress triglyceride biosynthesis through the farnesol pathway in rat hepatocytes. | Journal of lipid research 20030101 |
| HMG-CoA reductase inhibition aborts functional differentiation and triggers apoptosis in cultured primary human monocytes: a potential mechanism of statin-mediated vasculoprotection. | BMC cardiovascular disorders 20030101 |
| Pughiinin A, a sesquiterpene from the fungus Kionochaeta pughii BCC 3878. | Planta medica 20021101 |
| Simultaneous evaluation of HMG-CoA reductase and cholesterol 7alpha-hydroxylase activities by electrospray tandem MS. | Lipids 20021101 |
| [Mevalonolactone: a volatile compound produced by Psammotettix alienus (Dhb)]. | Comptes rendus biologies 20020901 |
| Mevastatin induces degeneration and decreases viability of cAMP-induced differentiated neuroblastoma cells in culture by inhibiting proteasome activity, and mevalonic acid lactone prevents these effects. | Journal of neuroscience research 20020601 |
| CD43 polarization in unprimed T cells can be dissociated from raft coalescence by inhibition of HMG CoA reductase. | Blood 20020401 |
| Investigation of a functional requirement for isoprenylation by the human prostacyclin receptor. | European journal of biochemistry 20020301 |
| Prolonged inhibition of cholesterol synthesis by atorvastatin inhibits apo B-100 and triglyceride secretion from HepG2 cells. | Atherosclerosis 20010701 |
| Progesterone inhibits apolipoprotein-mediated cellular lipid release: a putative mechanism for the decrease of high-density lipoprotein. | Biochimica et biophysica acta 20010629 |
| Biosynthesis of 2-methyl-3-buten-2-ol emitted from needles of Pinus ponderosa via the non-mevalonate DOXP/MEP pathway of isoprenoid formation. | Planta 20010601 |
| Isoprenoid biosynthesis is not compromised in a Zellweger syndrome mouse model. | Biochimica et biophysica acta 20010531 |
| Analysis of 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors using liquid chromatography-electrospray mass spectrometry. | Journal of chromatography. B, Biomedical sciences and applications 20010425 |
| Synthetic applications of epoxide hydrolases. | Current opinion in chemical biology 20010401 |
| Prenyl group identification of rap2 proteins: a ras superfamily member other than ras that is farnesylated. | The Biochemical journal 19930115 |
| The gamma subunit of transducin is farnesylated. | Proceedings of the National Academy of Sciences of the United States of America 19901001 |
| Lipid and lipoprotein metabolism in Hep G2 cells. | Biochimica et biophysica acta 19880812 |