4-[(7-chloroquinolin-4-yl)amino]-2-[(diethylamino)methyl]phenol dihydrate dihydrochloride
| Title | Journal |
|---|---|
| Human glutathione S-transferases- and NAD(P)H:quinone oxidoreductase 1-catalyzed inactivation of reactive quinoneimines of amodiaquine and N-desethylamodiaquine: Possible implications for susceptibility to amodiaquine-induced liver toxicity. | Toxicology letters 20170605 |
| The effect of milk thistle (Silybum marianum) and its main flavonolignans on CYP2C8 enzyme activity in human liver microsomes. | Chemico-biological interactions 20170601 |
| Involvement of myeloperoxidase and NADPH oxidase in the covalent binding of amodiaquine and clozapine to neutrophils: implications for drug-induced agranulocytosis. | Chemical research in toxicology 20140421 |
| The antimalarial amodiaquine causes autophagic-lysosomal and proliferative blockade sensitizing human melanoma cells to starvation- and chemotherapy-induced cell death. | Autophagy 20131201 |
| Tetrazole-based deoxyamodiaquines: synthesis, ADME/PK profiling and pharmacological evaluation as potential antimalarial agents. | Bioorganic & medicinal chemistry 20130901 |
| Ex vivo responses of Plasmodium falciparum clinical isolates to conventional and new antimalarial drugs in Niger. | Antimicrobial agents and chemotherapy 20130701 |
| Biowaiver monographs for immediate release solid oral dosage forms: amodiaquine hydrochloride. | Journal of pharmaceutical sciences 20121201 |
| A simple dose regimen of artesunate and amodiaquine based on arm span- or age range for childhood falciparum malaria: a preliminary evaluation. | Journal of tropical pediatrics 20120801 |
| Investigation of the interaction between amodiaquine and human serum albumin by fluorescence spectroscopy and molecular modeling. | European journal of medicinal chemistry 20120801 |
| Benzoheterocyclic amodiaquine analogues with potent antiplasmodial activity: synthesis and pharmacological evaluation. | Bioorganic & medicinal chemistry letters 20120801 |
| Crystal structure of phosphoethanolamine methyltransferase from Plasmodium falciparum in complex with amodiaquine. | Bioorganic & medicinal chemistry letters 20120801 |
| Artesunate- and amodiaquine-associated extrapyramidal reactions: a series of 49 cases in VigiBase™. | Drug safety 20120801 |
| Confirmation of Frm2 as a novel nitroreductase in Saccharomyces cerevisiae. | Biochemical and biophysical research communications 20120713 |
| A simple dose regimen of artesunate and amodiaquine based on age or body weight range for uncomplicated falciparum malaria in children: comparison of therapeutic efficacy with standard dose regimen of artesunate and amodiaquine and artemether-lumefantrine. | American journal of therapeutics 20120701 |
| Repeated artemisinin-based combination therapies in a malaria hyperendemic area of Mali: efficacy, safety, and public health impact. | The American journal of tropical medicine and hygiene 20120701 |
| Antimalarial efficacy of a quantified extract of Nauclea pobeguinii stem bark in human adult volunteers with diagnosed uncomplicated falciparum malaria. Part 2: a clinical phase IIB trial. | Planta medica 20120601 |
| Efficacy of different primaquine-based antimalarial regimens against Plasmodium falciparum gametocytemia. | Acta tropica 20120501 |
| Gene, ethnic and gender influences predisposition of adverse drug reactions to artesunate among Malaysians. | Toxicology mechanisms and methods 20120401 |
| In vitro assessment of drug resistance in Plasmodium falciparum in five States of India. | The Indian journal of medical research 20120401 |
| A modified serial blood sampling technique and utility of dried-blood spot technique in estimation of blood concentration: application in mouse pharmacokinetics. | European journal of drug metabolism and pharmacokinetics 20120301 |
| Intermittent preventive treatment for malaria in Papua New Guinean infants exposed to Plasmodium falciparum and P. vivax: a randomized controlled trial. | PLoS medicine 20120301 |
| Compliance, safety, and effectiveness of fixed-dose artesunate-amodiaquine for presumptive treatment of non-severe malaria in the context of home management of malaria in Madagascar. | The American journal of tropical medicine and hygiene 20120201 |
| Different patterns of pfcrt and pfmdr1 polymorphisms in P. falciparum isolates from Nigeria and Brazil: the potential role of antimalarial drug selection pressure. | The American journal of tropical medicine and hygiene 20120201 |
| A ferrocene-based reagent for the conjugation and quantification of reactive metabolites. | Analytical and bioanalytical chemistry 20120101 |
| Comparing changes in haematologic parameters occurring in patients included in randomized controlled trials of artesunate-amodiaquine vs single and combination treatments of uncomplicated falciparum in sub-Saharan Africa. | Malaria journal 20120101 |
| Artesunate-amodiaquine fixed dose combination for the treatment of Plasmodium falciparum malaria in India. | Malaria journal 20120101 |
| Distribution of human CYP2C8*2 allele in three different African populations. | Malaria journal 20120101 |
| Capillary electrophoresis for the assay of fixed-dose combination tablets of artesunate and amodiaquine. | Malaria journal 20120101 |
| Efficacy of fixed-dose combination artesunate-amodiaquine versus artemether-lumefantrine for uncomplicated childhood Plasmodium falciparum malaria in Democratic Republic of Congo: a randomized non-inferiority trial. | Malaria journal 20120101 |
| The efficacy and tolerability of artemisinin-piperaquine (Artequick®) versus artesunate-amodiaquine (Coarsucam™) for the treatment of uncomplicated Plasmodium falciparum malaria in south-central Vietnam. | Malaria journal 20120101 |
| Decreased prevalence of Plasmodium falciparum resistance markers to amodiaquine despite its wide scale use as ACT partner drug in Zanzibar. | Malaria journal 20120101 |
| Enhanced screening of glutathione-trapped reactive metabolites by in-source collision-induced dissociation and extraction of product ion using UHPLC-high resolution mass spectrometry. | Analytical chemistry 20111215 |
| In vitro amodiaquine resistance and its association with mutations in pfcrt and pfmdr1 genes of Plasmodium falciparum isolates from Nigeria. | Acta tropica 20111201 |
| A head-to-head comparison of four artemisinin-based combinations for treating uncomplicated malaria in African children: a randomized trial. | PLoS medicine 20111101 |
| Administrative practices of health professionals and use of artesunate-amodiaquine by community members for treating uncomplicated malaria in southern Ghana: implications for artemisinin-based combination therapy deployment. | Tropical medicine & international health : TM & IH 20111001 |
| Prolonged selection of pfmdr1 polymorphisms after treatment of falciparum malaria with artemether-lumefantrine in Uganda. | The Journal of infectious diseases 20111001 |
| Evaluation of CYP2C8 inhibition in vitro: utility of montelukast as a selective CYP2C8 probe substrate. | Drug metabolism and disposition: the biological fate of chemicals 20110901 |
| Antimalarial mannoxanes: hybrid antimalarial drugs with outstanding oral activity profiles and a potential dual mechanism of action. | ChemMedChem 20110801 |
| Use of the NP-40 detergent-mediated assay in discovery of inhibitors of beta-hematin crystallization. | Antimicrobial agents and chemotherapy 20110701 |
| Buchwald reaction as the key step for the synthesis of metabolically more stable analogs of amodiaquine. | European journal of medicinal chemistry 20110701 |
| Species differences in intestinal metabolic activities of cytochrome P450 isoforms between cynomolgus monkeys and humans. | Drug metabolism and pharmacokinetics 20110601 |
| Therapeutic efficacies of artemisinin-based combination therapies in Nigerian children with uncomplicated falciparum malaria during five years of adoption as first-line treatments. | The American journal of tropical medicine and hygiene 20110601 |
| Therapeutic efficacy and effects of artemether-lumefantrine and artesunate-amodiaquine coformulated or copackaged on malaria-associated anemia in children with uncomplicated Plasmodium falciparum malaria in Southwest Nigeria. | The American journal of tropical medicine and hygiene 20110505 |
| Use of area under the curve to evaluate the effects of antimalarial drugs on malaria-associated anemia after treatment. | American journal of therapeutics 20110501 |
| In vitro activity of Proveblue (methylene blue) on Plasmodium falciparum strains resistant to standard antimalarial drugs. | Antimicrobial agents and chemotherapy 20110501 |
| Amodiaquine analogues containing NO-donor substructures: synthesis and their preliminary evaluation as potential tools in the treatment of cerebral malaria. | European journal of medicinal chemistry 20110501 |
| The hydroxyl functionality and a rigid proximal N are required for forming a novel non-covalent quinine-heme complex. | Journal of inorganic biochemistry 20110301 |
| Comparative oral bioavailability of non-fixed and fixed combinations of artesunate and amodiaquine in healthy Indian male volunteers. | European journal of clinical pharmacology 20110301 |
| Intermittent preventive treatment to reduce the burden of malaria in children: new evidence on integration and delivery. | PLoS medicine 20110201 |
| Two strategies for the delivery of IPTc in an area of seasonal malaria transmission in the Gambia: a randomised controlled trial. | PLoS medicine 20110201 |
| Intermittent preventive treatment of malaria provides substantial protection against malaria in children already protected by an insecticide-treated bednet in Burkina Faso: a randomised, double-blind, placebo-controlled trial. | PLoS medicine 20110201 |
| Plasmodium falciparum: Solanum nudum SN-1 steroid antiplasmodial activity when combined with antimalarial drugs. | Experimental parasitology 20110101 |
| Effects of co-administration of artesunate and amodiaquine on some cardiovascular disease indices in rats. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20110101 |
| Is parasite clearance clinically important after malaria treatment in a high transmission area? A 3-month follow-up of home-based management with herbal medicine or ACT. | Transactions of the Royal Society of Tropical Medicine and Hygiene 20110101 |
| A trial of intermittent preventive treatment and home-based management of malaria in a rural area of The Gambia. | Malaria journal 20110101 |
| Access to artesunate-amodiaquine, quinine and other anti-malarials: policy and markets in Burundi. | Malaria journal 20110101 |
| A study of toxicity and differential gene expression in murine liver following exposure to anti-malarial drugs: amodiaquine and sulphadoxine-pyrimethamine. | Malaria journal 20110101 |
| Two-year evaluation of Intermittent Preventive Treatment for Children (IPTc) combined with timely home treatment for malaria control in Ghana. | Malaria journal 20110101 |
| The initial pharmaceutical development of an artesunate/amodiaquine oral formulation for the treatment of malaria: a public-private partnership. | Malaria journal 20110101 |
| Innovative public-private partnerships to maximize the delivery of anti-malarial medicines: lessons learned from the ASAQ Winthrop experience. | Malaria journal 20110101 |
| Changing patterns of malaria during 1996-2010 in an area of moderate transmission in southern Senegal. | Malaria journal 20110101 |
| Repeated treatment of recurrent uncomplicated Plasmodium falciparum malaria in Senegal with fixed-dose artesunate plus amodiaquine versus fixed-dose artemether plus lumefantrine: a randomized, open-label trial. | Malaria journal 20110101 |
| Malaria morbidity in children in the year after they had received intermittent preventive treatment of malaria in Mali: a randomized control trial. | PloS one 20110101 |
| Morbidity from malaria in children in the year after they had received intermittent preventive treatment of malaria: a randomised trial. | PloS one 20110101 |
| Effects of amodiaquine and artesunate on sulphadoxine-pyrimethamine pharmacokinetic parameters in children under five in Mali. | Malaria journal 20110101 |
| Management of uncomplicated malaria in children under 13 years of age at a district hospital in Senegal: from official guidelines to usual practices. | Malaria journal 20110101 |
| A thirteen-year analysis of Plasmodium falciparum populations reveals high conservation of the mutant pfcrt haplotype despite the withdrawal of chloroquine from national treatment guidelines in Gabon. | Malaria journal 20110101 |
| Impact of combining intermittent preventive treatment with home management of malaria in children less than 10 years in a rural area of Senegal: a cluster randomized trial. | Malaria journal 20110101 |
| Therapeutic efficacy and effect on gametocyte carriage of an artemisinin and a non-based combination treatment in children with uncomplicated P. falciparum malaria, living in an area with high-level chloroquine resistance. | Journal of tropical pediatrics 20101201 |
| Alternative visual displays of metaanalysis of malaria treatment trials to facilitate translation of research into policy. | Diagnostic microbiology and infectious disease 20101201 |
| Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. | Bioorganic & medicinal chemistry letters 20101101 |
| Fixed artesunate-amodiaquine combined pre-formulation study for the treatment of malaria. | International journal of pharmaceutics 20100816 |
| Synergy of mefloquine activity with atorvastatin, but not chloroquine and monodesethylamodiaquine, and association with the pfmdr1 gene. | The Journal of antimicrobial chemotherapy 20100701 |
| In vitro susceptibility of Plasmodium falciparum to monodesethylamodiaquine, quinine, mefloquine and halofantrine in Abidjan (Côte d'Ivoire). | African health sciences 20100601 |
| Successful introduction of artesunate combination therapy is not enough to fight malaria: results from an adherence study in Sierra Leone. | Transactions of the Royal Society of Tropical Medicine and Hygiene 20100501 |
| Efficacy and tolerability of artesunate-amodiaquine (Camoquin plus) versus artemether-lumefantrine (Coartem) against uncomplicated Plasmodium falciparum malaria: multisite trial in Senegal and Ivory Coast. | Tropical medicine & international health : TM & IH 20100501 |
| Selection of known Plasmodium falciparum resistance-mediating polymorphisms by artemether-lumefantrine and amodiaquine-sulfadoxine-pyrimethamine but not dihydroartemisinin-piperaquine in Burkina Faso. | Antimicrobial agents and chemotherapy 20100501 |
| Selection of pfmdr1 and pfcrt alleles in amodiaquine treatment failure in north-western Burkina Faso. | Acta tropica 20100401 |
| Design of a fixed-dose paediatric combination of artesunate and amodiaquine hydrochloride. | International journal of pharmaceutics 20100315 |
| Amodiaquine dosage and tolerability for intermittent preventive treatment to prevent malaria in children. | Antimicrobial agents and chemotherapy 20100301 |
| In vitro sensitivity of Plasmodium falciparum to conventional and novel antimalarial drugs in Papua New Guinea. | Tropical medicine & international health : TM & IH 20100301 |
| A controlled trial to assess the effect of quinine, chloroquine, amodiaquine, and artesunate on Loa loa microfilaremia. | The American journal of tropical medicine and hygiene 20100301 |
| Argemone mexicana decoction versus artesunate-amodiaquine for the management of malaria in Mali: policy and public-health implications. | Transactions of the Royal Society of Tropical Medicine and Hygiene 20100101 |
| Plasmodium falciparum resistance to anti-malarial drugs in Papua New Guinea: evaluation of a community-based approach for the molecular monitoring of resistance. | Malaria journal 20100101 |
| Identification of inhibitors of Plasmodium falciparum phosphoethanolamine methyltransferase using an enzyme-coupled transmethylation assay. | BMC biochemistry 20100101 |
| Efficacy of amodiaquine, sulphadoxine-pyrimethamine and their combination for the treatment of uncomplicated Plasmodium falciparum malaria in children in Cameroon at the time of policy change to artemisinin-based combination therapy. | Malaria journal 20100101 |
| Efficacy of non-artemisinin- and artemisinin-based combination therapies for uncomplicated falciparum malaria in Cameroon. | Malaria journal 20100101 |
| Revisiting the circulation time of Plasmodium falciparum gametocytes: molecular detection methods to estimate the duration of gametocyte carriage and the effect of gametocytocidal drugs. | Malaria journal 20100101 |
| Analysis of an ordinal outcome in a multicentric randomized controlled trial: application to a 3- arm anti- malarial drug trial in Cameroon. | BMC medical research methodology 20100101 |
| Incidence of malaria and efficacy of combination antimalarial therapies over 4 years in an urban cohort of Ugandan children. | PloS one 20100101 |
| Cost effectiveness of seasonal intermittent preventive treatment using amodiaquine & artesunate or sulphadoxine-pyrimethamine in Ghanaian children. | PloS one 20100101 |
| Vasorelaxation induced by amodiaquine in rat superior mesenteric arteries: in vivo and in vitro studies. | Acta poloniae pharmaceutica 20100101 |
| Influences of intermittent preventive treatment and persistent multiclonal Plasmodium falciparum infections on clinical malaria risk. | PloS one 20100101 |
| Early variations in plasmodium falciparum dynamics in Nigerian children after treatment with two artemisinin-based combinations: implications on delayed parasite clearance. | Malaria journal 20100101 |
| Protecting the malaria drug arsenal: halting the rise and spread of amodiaquine resistance by monitoring the PfCRT SVMNT type. | Malaria journal 20100101 |
| An open randomized clinical trial in comparing two artesunate-based combination treatments on Plasmodium falciparum malaria in Nigerian children: artesunate/sulphamethoxypyrazine/pyrimethamine (fixed dose over 24 hours) versus artesunate/amodiaquine (fixed dose over 48 hours). | Malaria journal 20100101 |
| Mode of action and choice of antimalarial drugs for intermittent preventive treatment in infants. | Transactions of the Royal Society of Tropical Medicine and Hygiene 20091201 |
| A new series of amodiaquine analogues modified in the basic side chain with in vitro antileishmanial and antiplasmodial activity. | European journal of medicinal chemistry 20091201 |
| Selection of parasites with diminished drug susceptibility by amodiaquine-containing antimalarial regimens in Uganda. | The Journal of infectious diseases 20091201 |
| Cytochrome P450 enzymes and genotype-guided drug therapy. | Current opinion in molecular therapeutics 20091201 |
| Comparative study of artesunate, ACTs and their combinants on the hormonal parameters of the male guinea pig. | Nigerian journal of physiological sciences : official publication of the Physiological Society of Nigeria 20091201 |
| Artemisinin resistance on the Thai-Cambodian border. | Lancet (London, England) 20091024 |
| Tolerability and pharmacokinetics of non-fixed and fixed combinations of artesunate and amodiaquine in Malaysian healthy normal volunteers. | European journal of clinical pharmacology 20090801 |
| Plasmodium berghei ANKA: selection of resistance to piperaquine and lumefantrine in a mouse model. | Experimental parasitology 20090701 |
| Comparison of sulfadoxine-pyrimethamine, unsupervised artemether-lumefantrine, and unsupervised artesunate-amodiaquine fixed-dose formulation for uncomplicated plasmodium falciparum malaria in Benin: a randomized effectiveness noninferiority trial. | The Journal of infectious diseases 20090701 |
| Metabolism-dependent hepatotoxicity of amodiaquine in glutathione-depleted mice. | Archives of toxicology 20090701 |
| Adherence to artesunate-amodiaquine combination therapy for uncomplicated malaria in children in Zanzibar, Tanzania. | Tropical medicine & international health : TM & IH 20090701 |
| A microfluidic chip for electrochemical conversions in drug metabolism studies. | Lab on a chip 20090621 |
| In vivo and in vitro efficacy of amodiaquine against Plasmodium falciparum in an area of continued use of 4-aminoquinolines in East Africa. | The Journal of infectious diseases 20090601 |
| Impact of ministry of health interventions on private medicine retailer knowledge and practices on anti-malarial treatment in Kenya. | The American journal of tropical medicine and hygiene 20090601 |
| Efficacy of artemisinin-based combination therapy for treatment of persons with uncomplicated Plasmodium falciparum malaria in West Sumba District, East Nusa Tenggara Province, Indonesia, and genotypic profiles of the parasite. | The American journal of tropical medicine and hygiene 20090601 |
| Comparative study of artesunate, ACTs and their combinants on the spermatic parameters of the male guinea pig. | Nigerian journal of physiological sciences : official publication of the Physiological Society of Nigeria 20090601 |
| Open label randomized comparison of dihydroartemisinin-piperaquine and artesunate-amodiaquine for the treatment of uncomplicated Plasmodium falciparum malaria in central Vietnam. | Tropical medicine & international health : TM & IH 20090501 |
| High prevalence of CYP2A6*4 and CYP2A6*9 alleles detected among a Malaysian population. | Clinica chimica acta; international journal of clinical chemistry 20090501 |
| Synthesis, antimalarial activity, and preclinical pharmacology of a novel series of 4'-fluoro and 4'-chloro analogues of amodiaquine. Identification of a suitable 'back-up' compound for N-tert-butyl isoquine. | Journal of medicinal chemistry 20090409 |
| Biological measure of compliance to Artesunate plus Amodiaquine association: interest in a Mono-Desethyl-Amodiaquine blood assay? | Acta tropica 20090401 |
| Replacement of the 4'-hydroxy group of amodiaquine and amopyroquine by aromatic and aliphatic substituents: synthesis and antimalarial activity. | ChemMedChem 20090401 |
| Candidate selection and preclinical evaluation of N-tert-butyl isoquine (GSK369796), an affordable and effective 4-aminoquinoline antimalarial for the 21st century. | Journal of medicinal chemistry 20090312 |
| Novel metabolites of amodiaquine formed by CYP1A1 and CYP1B1: structure elucidation using electrochemistry, mass spectrometry, and NMR. | Drug metabolism and disposition: the biological fate of chemicals 20090301 |
| In-vivo efficacy of amodiaquine-artesunate in children with uncomplicated Plasmodium falciparum malaria in western Kenya. | Tropical medicine & international health : TM & IH 20090301 |
| Decreasing efficacy of antimalarial combination therapy in Uganda is explained by decreasing host immunity rather than increasing drug resistance. | The Journal of infectious diseases 20090301 |
| Validation of high performance liquid chromatography-electrochemical detection methods with simultaneous extraction procedure for the determination of artesunate, dihydroartemisinin, amodiaquine and desethylamodiaquine in human plasma for application in clinical pharmacological studies of artesunate-amodiaquine drug combination. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090215 |
| Amodiaquine-induced oxidative stress in a hepatocyte inflammation model. | Toxicology 20090204 |
| Efficacy of monotherapies and artesunate-based combination therapies in children with uncomplicated malaria in Somalia. | Acta tropica 20090201 |
| [Permanent deafness following typhoid fever: case report from Dakar, Senegal]. | Medecine tropicale : revue du Corps de sante colonial 20090201 |
| Intermittent preventive treatment with antimalarial drugs. | Lancet (London, England) 20090103 |
| Screening and characterization of reactive metabolites using glutathione ethyl ester in combination with Q-trap mass spectrometry. | Journal of mass spectrometry : JMS 20090101 |
| Effects of amodiaquine, artesunate, and artesunate-amodiaquine on Plasmodium falciparum malaria-associated anaemia in children. | Acta tropica 20090101 |
| [Two cases of fulminant hepatitis during a curative treatment with an artesunate-amodiaquine combination]. | Medecine et maladies infectieuses 20090101 |
| Dosing accuracy of artesunate and amodiaquine as treatment for falciparum malaria in Casamance, Senegal. | Tropical medicine & international health : TM & IH 20090101 |
| Pattern of drug utilization for treatment of uncomplicated malaria in urban Ghana following national treatment policy change to artemisinin-combination therapy. | Malaria journal 20090101 |
| Artemisinin-based combinations versus amodiaquine plus sulphadoxine-pyrimethamine for the treatment of uncomplicated malaria in Faladje, Mali. | Malaria journal 20090101 |
| Efficacy of chloroquine, amodiaquine and sulphadoxine-pyrimethamine for the treatment of uncomplicated falciparum malaria: revisiting molecular markers in an area of emerging AQ and SP resistance in Mali. | Malaria journal 20090101 |
| The efficacy and safety of a new fixed-dose combination of amodiaquine and artesunate in young African children with acute uncomplicated Plasmodium falciparum. | Malaria journal 20090101 |
| Field-adapted sampling of whole blood to determine the levels of amodiaquine and its metabolite in children with uncomplicated malaria treated with amodiaquine plus artesunate combination. | Malaria journal 20090101 |
| Randomized trial of artesunate+amodiaquine, sulfadoxine-pyrimethamine+amodiaquine, chlorproguanal-dapsone and SP for malaria in pregnancy in Tanzania. | PloS one 20090101 |
| Strong gametocytocidal effect of methylene blue-based combination therapy against falciparum malaria: a randomised controlled trial. | PloS one 20090101 |
| Factors related to compliance to anti-malarial drug combination: example of amodiaquine/sulphadoxine-pyrimethamine among children in rural Senegal. | Malaria journal 20090101 |
| Randomized, multicentre assessment of the efficacy and safety of ASAQ--a fixed-dose artesunate-amodiaquine combination therapy in the treatment of uncomplicated Plasmodium falciparum malaria. | Malaria journal 20090101 |
| Treatment of malaria from monotherapy to artemisinin-based combination therapy by health professionals in rural health facilities in southern Cameroon. | Malaria journal 20090101 |
| Treatment of malaria from monotherapy to artemisinin-based combination therapy by health professionals in urban health facilities in Yaoundé, central province, Cameroon. | Malaria journal 20090101 |
| Varying efficacy of artesunate+amodiaquine and artesunate+sulphadoxine-pyrimethamine for the treatment of uncomplicated falciparum malaria in the Democratic Republic of Congo: a report of two in-vivo studies. | Malaria journal 20090101 |
| Population pharmacokinetics of artesunate and amodiaquine in African children. | Malaria journal 20090101 |
| Efficacy of artesunate-amodiaquine for treating uncomplicated falciparum malaria in sub-Saharan Africa: a multi-centre analysis. | Malaria journal 20090101 |
| Bioavailability of a co-formulated combination of amodiaquine and artesunate under fed and fasted conditions. A randomised, open-label crossover study. | Arzneimittel-Forschung 20090101 |
| PfHRP2 and PfLDH antigen detection for monitoring the efficacy of artemisinin-based combination therapy (ACT) in the treatment of uncomplicated falciparum malaria. | Malaria journal 20090101 |
| Options for the delivery of intermittent preventive treatment for malaria to children: a community randomised trial. | PloS one 20090101 |
| Self-reported data: a major tool to assess compliance with anti-malarial combination therapy among children in Senegal. | Malaria journal 20090101 |
| Effectiveness of combined intermittent preventive treatment for children and timely home treatment for malaria control. | Malaria journal 20090101 |
| Pharmacokinetics and pharmacodynamics of a new ACT formulation: Artesunate/Amodiaquine (TRIMALACT) following oral administration in African malaria patients. | European journal of drug metabolism and pharmacokinetics 20090101 |
| Covalent protein modification by reactive drug metabolites using online electrochemistry/liquid chromatography/mass spectrometry. | Analytical chemistry 20081215 |
| Single-dose pharmacokinetic interaction between artesunate and amodiaquine: assembling the clues for the purported interaction. | European journal of clinical pharmacology 20081201 |
| Some features of primary and recrudescent amodiaquine-resistant Plasmodium falciparum infections in Nigerian children. | Memorias do Instituto Oswaldo Cruz 20081201 |
| pfmdr1 mutations in imported African Plasmodium falciparum isolates. | Transactions of the Royal Society of Tropical Medicine and Hygiene 20081101 |
| Intermittent preventive antimalarial treatment to children (IPTc): firebreak or fire trap? | Trends in parasitology 20081101 |
| dhfr and dhps genotype and sulfadoxine-pyrimethamine treatment failure in children with falciparum malaria in the Democratic Republic of Congo. | Tropical medicine & international health : TM & IH 20081101 |
| A randomized, controlled trial of intermittent preventive treatment with sulfadoxine-pyrimethamine, amodiaquine, or the combination in pregnant women in Ghana. | The Journal of infectious diseases 20081015 |
| A randomized, comparative study of supervised and unsupervised artesunate-amodiaquine, for the treatment of uncomplicated malaria in Ghana. | Annals of tropical medicine and parasitology 20081001 |
| Monitoring Plasmodium falciparum chloroquine resistance in Yunnan Province, China, 1981-2006. | Acta tropica 20081001 |
| Amodiaquine pharmacogenetics. | Pharmacogenomics 20081001 |
| Mutations in PFCRT K76T do not correlate with sulfadoxine-pyrimethamine-amodiaquine failure in Pikine, Senegal. | Parasitology research 20080901 |
| Lysosomal trapping of amodiaquine: impact on transport across intestinal epithelia models. | Biopharmaceutics & drug disposition 20080901 |
| Lysosomotropic drugs inhibit maturation of transforming growth factor-beta. | Canadian journal of physiology and pharmacology 20080901 |
| Synthesis and antimalarial activity of new amino analogues of amodiaquine. | Medicinal chemistry (Shariqah (United Arab Emirates)) 20080901 |
| Effects of amodiaquine hydrochloride and artemisinin on indomethacin-induced lipid peroxidation in rats. | Pakistan journal of biological sciences : PJBS 20080901 |
| Molecular markers of in vivo Plasmodium vivax resistance to amodiaquine plus sulfadoxine-pyrimethamine: mutations in pvdhfr and pvmdr1. | The Journal of infectious diseases 20080801 |
| Adherence and effectiveness of drug combination in curative treatment among children suffering uncomplicated malaria in rural Senegal. | Transactions of the Royal Society of Tropical Medicine and Hygiene 20080801 |
| Novel amodiaquine congeners as potent antimalarial agents. | Bioorganic & medicinal chemistry 20080715 |
| Effect of intermittent preventive treatment of malaria on health and education in schoolchildren: a cluster-randomised, double-blind, placebo-controlled trial. | Lancet (London, England) 20080712 |
| Activities of artesunate and amodiaquine against intestinal helminth in children with Plasmodium falciparum malaria in endemic areas. | European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20080701 |
| Pharmacokinetics and tolerability of artesunate and amodiaquine alone and in combination in healthy volunteers. | European journal of clinical pharmacology 20080701 |
| Investigation of amodiaquine bulk drug impurities by liquid chromatography/ion trap mass spectrometry. | Rapid communications in mass spectrometry : RCM 20080701 |
| Biological and haematological safety profile of oral amodiaquine and chloroquine in healthy volunteers with or without Plasmodium falciparum infection in northeast Tanzania. | Tanzania journal of health research 20080701 |
| Effects of artesunate-cotrimoxazole and amodiaquine-artesunate against asexual and sexual stages of Plasmodium falciparum malaria in Nigerian children. | Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20080601 |
| [Gametocytemia in falciparum malaria treated with amodiaquine or artesunate]. | Biomedica : revista del Instituto Nacional de Salud 20080601 |
| High efficacy of two artemisinin-based combinations (artemether-lumefantrine and artesunate plus amodiaquine) for acute uncomplicated malaria in Ibadan, Nigeria. | Tropical medicine & international health : TM & IH 20080501 |
| Electrochemical generation of electrophilic drug metabolites: characterization of amodiaquine quinoneimine and cysteinyl conjugates by MS, IR, and NMR. | Chemical research in toxicology 20080401 |
| Studies on antimalarial drug susceptibility in Colombia, in relation to Pfmdr1 and Pfcrt. | Parasitology 20080401 |
| High risk of neutropenia in HIV-infected children following treatment with artesunate plus amodiaquine for uncomplicated malaria in Uganda. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20080401 |
| Disease and drug interactions: treating malaria with artesunate plus amodiaquine in patients also receiving treatment for concomitant HIV infection. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20080401 |
| [Assessing the application of Rwanda's national protocol for uncomplicated malaria treatment in healthcare institutions in Kigali City, Rwanda]. | Medecine et maladies infectieuses 20080301 |
| Increased Plasmodium falciparum gametocyte production in mixed infections with P. malariae. | The American journal of tropical medicine and hygiene 20080301 |
| Efficacy, safety, and selection of molecular markers of drug resistance by two ACTs in Mali. | The American journal of tropical medicine and hygiene 20080301 |
| [Efficacy of the amodiaquine+sulfadoxine-pyrimethamine combination and of chloroquine for the treatment of malaria in Córdoba, Colombia, 2006]. | Biomedica : revista del Instituto Nacional de Salud 20080301 |
| Determination of N-desethylamodiaquine by hydrophilic interaction liquid chromatography with tandem mass spectrometry: application to in vitro drug metabolism studies. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080215 |
| Synthesis and antimalarial activity of new analogues of amodiaquine. | European journal of medicinal chemistry 20080201 |
| Synthesis and in vitro cytotoxicity evaluation of 4-aminoquinoline derivatives. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20080201 |
| Antimalarial resistance and DHFR/DHPS genotypes of Plasmodium falciparum three years after introduction of sulfadoxine-pyrimethamine and amodiaquine in rural Tanzania. | Transactions of the Royal Society of Tropical Medicine and Hygiene 20080201 |
| Chloroquine-resistance molecular markers (Pfcrt T76 and Pfmdr-1 Y86) and amodiaquine resistance in Burkina Faso. | Tropical medicine & international health : TM & IH 20080201 |
| Chloroquine resistant Plasmodium falciparum malaria in Osogbo Nigeria: efficacy of amodiaquine + sulfadoxine-pyrimethamine and chloroquine + chlorpheniramine for treatment. | Memorias do Instituto Oswaldo Cruz 20080201 |
| Feasibility and acceptability of artemisinin-based combination therapy for the home management of malaria in four African sites. | Malaria journal 20080101 |
| Randomized, comparative study of the efficacy and safety of artesunate plus amodiaquine, administered as a single daily intake versus two daily intakes in the treatment of uncomplicated falciparum malaria. | Malaria journal 20080101 |
| A trial of the efficacy, safety and impact on drug resistance of four drug regimens for seasonal intermittent preventive treatment for malaria in Senegalese children. | PloS one 20080101 |
| Sulphadoxine/pyrimethamine versus amodiaquine for treating uncomplicated childhood malaria in Gabon: a randomized trial to guide national policy. | Malaria journal 20080101 |
| Safety and efficacy of methylene blue combined with artesunate or amodiaquine for uncomplicated falciparum malaria: a randomized controlled trial from Burkina Faso. | PloS one 20080101 |
| Enhanced efficacy of amodiaquine and chlorpheniramine combination over amodiaquine alone in the treatment of acute uncomplicated Plasmodium falciparum malaria in children. | Medical principles and practice : international journal of the Kuwait University, Health Science Centre 20080101 |
| Efficacy of amodiaquine in the treatment of uncomplicated falciparum malaria in young children of rural north-western Burkina Faso. | Malaria journal 20080101 |
| The usefulness of twenty-four molecular markers in predicting treatment outcome with combination therapy of amodiaquine plus sulphadoxine-pyrimethamine against falciparum malaria in Papua New Guinea. | Malaria journal 20080101 |
| Safety and tolerability of combination antimalarial therapies for uncomplicated falciparum malaria in Ugandan children. | Malaria journal 20080101 |
| Activities of artemether-lumefantrine and amodiaquine-sulfalene-pyrimethamine against sexual-stage parasites in falciparum malaria in children. | Chemotherapy 20080101 |
| An open label, randomised trial of artesunate+amodiaquine, artesunate+chlorproguanil-dapsone and artemether-lumefantrine for the treatment of uncomplicated malaria. | PloS one 20080101 |
| Amodiaquine-artesunate vs artemether-lumefantrine for uncomplicated malaria in Ghanaian children: a randomized efficacy and safety trial with one year follow-up. | Malaria journal 20080101 |
| Different methodological approaches to the assessment of in vivo efficacy of three artemisinin-based combination antimalarial treatments for the treatment of uncomplicated falciparum malaria in African children. | Malaria journal 20080101 |
| Plasmodium falciparum gametocyte sex ratios in children with acute, symptomatic, uncomplicated infections treated with amodiaquine. | Malaria journal 20080101 |
| Effectiveness of artemisinin-based combination therapy used in the context of home management of malaria: a report from three study sites in sub-Saharan Africa. | Malaria journal 20080101 |
| Trends in malaria morbidity following the introduction of artesunate plus amodiaquine combination in M'lomp village dispensary, south-western Senegal. | Malaria journal 20080101 |
| Malariological baseline survey and in vitro antimalarial drug resistance in Gulu district, Northern Uganda. | Wiener klinische Wochenschrift 20080101 |
| Pharmacodynamic interaction between 4-aminoquinolines and retinol in Plasmodium falciparum in vitro. | Wiener klinische Wochenschrift 20080101 |
| Seasonal intermittent preventive treatment for the prevention of anaemia and malaria in Ghanaian children: a randomized, placebo controlled trial. | PloS one 20080101 |
| A randomized trial on effectiveness of artemether-lumefantrine versus artesunate plus amodiaquine for unsupervised treatment of uncomplicated Plasmodium falciparum malaria in Ghanaian children. | Malaria journal 20080101 |
| High risk of severe anaemia after chlorproguanil-dapsone+artesunate antimalarial treatment in patients with G6PD (A-) deficiency. | PloS one 20080101 |
| The effect of administration of amodiaquine on some parameters of neurobehaviour of Wistar rats. | Nigerian journal of physiological sciences : official publication of the Physiological Society of Nigeria 20080101 |
| Randomized comparison of amodiaquine plus sulfadoxine-pyrimethamine, artemether-lumefantrine, and dihydroartemisinin-piperaquine for the treatment of uncomplicated Plasmodium falciparum malaria in Burkina Faso. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20071201 |
| Simultaneous determination of amodiaquine and its active metabolite in human blood by ion-pair liquid chromatography-tandem mass spectrometry. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20071201 |
| Short report: polymorphisms in the pfcrt and pfmdr1 genes of Plasmodium falciparum and in vitro susceptibility to amodiaquine and desethylamodiaquine. | The American journal of tropical medicine and hygiene 20071201 |
| Pharmacologic advances in the global control and treatment of malaria: combination therapy and resistance. | Clinical pharmacology and therapeutics 20071101 |
| A field-adapted HPLC method for determination of amodiaquine and its metabolite in whole blood dried on filter paper. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20071101 |
| The safety of amodiaquine use in pregnant women. | Expert opinion on drug safety 20071101 |
| Low efficacy of amodiaquine or chloroquine plus sulfadoxine-pyrimethamine against Plasmodium falciparum and P. vivax malaria in Papua New Guinea. | The American journal of tropical medicine and hygiene 20071101 |
| Clinical symptoms, treatment and outcome of highlands malaria in Eldoret (2420 m a.s.l.) and comparison to malaria in hyper-immune population in endemic region of Southern Sudan. | Neuro endocrinology letters 20071101 |
| Population pharmacokinetics of amodiaquine and desethylamodiaquine in pediatric patients with uncomplicated falciparum malaria. | Journal of pharmacokinetics and pharmacodynamics 20071001 |
| Selection of pfmdr1 mutations after amodiaquine monotherapy and amodiaquine plus artemisinin combination therapy in East Africa. | Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 20070901 |
| Efficacy of sulfadoxine-pyrimethamine, amodiaquine, and sulfadoxine-pyrimethamine-amodiaquine combination for the treatment of uncomplicated falciparum malaria in the urban and suburban areas of Brazzaville (Congo). | Acta tropica 20070901 |
| Amodiaquine metabolism is impaired by common polymorphisms in CYP2C8: implications for malaria treatment in Africa. | Clinical pharmacology and therapeutics 20070801 |
| Therapeutic efficacy and effects of artemether-lumefantrine and amodiaquine-sulfalene-pyrimethamine on gametocyte carriage in children with uncomplicated Plasmodium falciparum malaria in southwestern Nigeria. | The American journal of tropical medicine and hygiene 20070801 |
| A non-radiolabeled heme-GSH interaction test for the screening of antimalarial compounds. | Experimental parasitology 20070701 |
| The in-vitro susceptibilities of Ghanaian Plasmodium falciparum to antimalarial drugs. | Annals of tropical medicine and parasitology 20070701 |
| Artesunate-amodiaquine for the treatment of uncomplicated malaria. | Expert opinion on investigational drugs 20070701 |
| Emergency liver transplantation in amodiaquine-induced fulminant hepatitis. | The American journal of tropical medicine and hygiene 20070701 |
| Amodiaquine in future combination treatment of malaria in Ghana. | Tropical doctor 20070701 |
| Prevalent pfmdr1 n86y mutant Plasmodium falciparum in Madagascar despite absence of pfcrt mutant strains. | The American journal of tropical medicine and hygiene 20070601 |
| Efficacy of artesunate plus amodiaquine, artesunate plus sulfadoxine-pyrimethamine, and chloroquine plus sulfadoxine-pyrimethamine in patients with uncomplicated Plasmodium falciparum in the Comoros Union. | Acta tropica 20070601 |
| Enhancement of the antimalarial efficacy of amodiaquine by chlorpheniramine in vivo. | Memorias do Instituto Oswaldo Cruz 20070601 |
| [Polymorphisms of the pfmdr1 gene in field samples of Plasmodium falciparum and their association with therapeutic response to antimalarial drugs and severe malaria in Colombia]. | Biomedica : revista del Instituto Nacional de Salud 20070601 |
| [Tolerance of amodiaquine]. | Medecine tropicale : revue du Corps de sante colonial 20070601 |
| [Open radomized study comparing chloroquine and amodiaquine for treatment of uncomplicated plasmodium falciparum malaria in children in Aboisso, Cote d' Ivoire]. | Medecine tropicale : revue du Corps de sante colonial 20070601 |
| [A new, cheaper and simpler anti-malaria preparation]. | Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20070531 |
| Antimalarial drugs--here and on the horizon. | JAMA 20070523 |
| Combination therapy for uncomplicated falciparum malaria in Ugandan children: a randomized trial. | JAMA 20070523 |
| Plasmodium falciparum genotypes associated with chloroquine and amodiaquine resistance in Guinea-Bissau. | The American journal of tropical medicine and hygiene 20070501 |
| Dihydroartemisinin-piperaquine versus artesunate-amodiaquine: superior efficacy and posttreatment prophylaxis against multidrug-resistant Plasmodium falciparum and Plasmodium vivax malaria. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20070415 |
| A randomised trial to assess the safety and efficacy of artemether-lumefantrine (Coartem) for the treatment of uncomplicated Plasmodium falciparum malaria in Rwanda. | Transactions of the Royal Society of Tropical Medicine and Hygiene 20070401 |
| Effects of prior administration of amodiaquine on the disposition of halofantrine in healthy volunteers. | Therapeutic drug monitoring 20070401 |
| [ASAQ, a breakthrough in the fight against malaria]. | Medecine tropicale : revue du Corps de sante colonial 20070401 |
| Hepatotoxicity due to a drug interaction between amodiaquine plus artesunate and efavirenz. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20070315 |
| [Against malaria: ASAQ, one dollar per box]. | Revue medicale suisse 20070314 |
| Effect of amodiaquine, a histamine N-methyltransferase inhibitor, on, Propionibacterium acnes and lipopolysaccharide-induced hepatitis in mice. | European journal of pharmacology 20070308 |
| New once a day, fixed dose antimalarial is now available for adults and children. | BMJ (Clinical research ed.) 20070303 |
| Correlations between treatment outcome and both anti-MSP119 antibody response and erythrocyte-related genetic factors in Plasmodium falciparum malaria. | Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 20070301 |
| Different doses of amodiaquine and chloroquine for treatment of uncomplicated malaria in children in Guinea-Bissau: implications for future treatment recommendations. | Transactions of the Royal Society of Tropical Medicine and Hygiene 20070301 |
| Practical HPLC methods for the quantitative determination of common antimalarials in Africa. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070301 |
| In vitro assessment of artesunate, artemether and amodiaquine susceptibility and molecular analysis of putative resistance-associated mutations of Plasmodium falciparum from São Tomé and Príncipe. | Tropical medicine & international health : TM & IH 20070301 |
| The comparative efficacies of malartin, with and without amodiaquine, in the treatment of Plasmodium falciparum malaria in the Buea district of Cameroon. | Annals of tropical medicine and parasitology 20070301 |
| [Assessment of the efficacy of antimalarial drugs in Tarapacá, in the Colombian Amazon basin]. | Biomedica : revista del Instituto Nacional de Salud 20070301 |
| Chloroquine-resistant malaria in Malawi. | The New England journal of medicine 20070222 |
| Antimalarial drug combinations in vastly different settings. | Lancet (London, England) 20070210 |
| Artemether-lumefantrine versus amodiaquine plus sulfadoxine-pyrimethamine for uncomplicated falciparum malaria in Burkina Faso: a randomised non-inferiority trial. | Lancet (London, England) 20070210 |
| Antischistosomal efficacy of artesunate combination therapies administered as curative treatments for malaria attacks. | Transactions of the Royal Society of Tropical Medicine and Hygiene 20070201 |
| Amodiaquine combined with sulfadoxine/pyrimethamine versus artemisinin-based combinations for the treatment of uncomplicated falciparum malaria in Africa: a meta-analysis. | Transactions of the Royal Society of Tropical Medicine and Hygiene 20070201 |
| The effects of artemether-lumefantrine vs amodiaquine-sulfalene-pyrimethamine on the hepatomegaly associated with Plasmodium falciparum malaria in children. | Parasitology research 20070201 |
| [Benzo[c][2,7]naphthyridine-5-yl-arylamines-phenol Mannich bases of the amodiaquine-, cycloquine- and pyronaridine-type]. | Die Pharmazie 20070201 |
| In vitro efficacy, resistance selection, and structural modeling studies implicate the malarial parasite apicoplast as the target of azithromycin. | The Journal of biological chemistry 20070126 |
| Efficacies of artesunate plus either sulfadoxine-pyrimethamine or amodiaquine, for the treatment of uncomplicated, Plasmodium falciparum malaria in eastern Sudan. | Annals of tropical medicine and parasitology 20070101 |
| Artemisinin-based combination therapy for uncomplicated Plasmodium falciparum malaria in Colombia. | Malaria journal 20070101 |
| Artesunate--amodiaquine combination therapy for falciparum malaria in young Gabonese children. | Malaria journal 20070101 |
| Exploration of rate-limiting conformational state for 5-[(7-chloro-4-quinolinyl)amino]-3-[(alkylamino)methyl][1,1'-biphenyl]-2-ols and N(omega)-oxides (tebuquine analogues) for antimalarial activity using molecular shape analysis and molecular field analysis studies. | Journal of chemical information and modeling 20070101 |
| Amodiaquine failure associated with erythrocytic glutathione in Plasmodium falciparum malaria. | Malaria journal 20070101 |
| Efficacy of antimalarial treatment in Guinea: in vivo study of two artemisinin combination therapies in Dabola and molecular markers of resistance to sulphadoxine-pyrimethamine in N'Zérékoré. | Malaria journal 20070101 |
| Randomized clinical trial of artemisinin versus non-artemisinin combination therapy for uncomplicated falciparum malaria in Madagascar. | Malaria journal 20070101 |
| Efficacy and tolerability of four antimalarial combinations in the treatment of uncomplicated Plasmodium falciparum malaria in Senegal. | Malaria journal 20070101 |
| [Place of artemisinin derivatives as anti-malarial drugs in paediatric hospitalization in Abidjan]. | Therapie 20070101 |
| Community coverage of an antimalarial combination of artesunate and amodiaquine in Makamba Province, Burundi, nine months after its introduction. | Malaria journal 20070101 |
| [Therapeutic efficacy of amodiaquine against uncomplicated malaria in Madagascar]. | Sante (Montrouge, France) 20070101 |
| Efficacy and safety of artemisinin-based antimalarial in the treatment of uncomplicated malaria in children in southern Tanzania. | Malaria journal 20070101 |
| Efficacy and safety of artesunate plus amodiaquine in routine use for the treatment of uncomplicated malaria in Casamance, southern Sénégal. | Malaria journal 20070101 |
| Potential impact of host immunity on malaria treatment outcome in Tanzanian children infected with Plasmodium falciparum. | Malaria journal 20070101 |
| Photophysical properties and photobiological behavior of amodiaquine, primaquine and chloroquine. | Photochemistry and photobiology 20070101 |
| Amodiaquine resistance is not related to rare findings of pfmdr1 gene amplifications in Kenya. | Tropical medicine & international health : TM & IH 20061201 |
| Use of weight-for-age-data to optimize tablet strength and dosing regimens for a new fixed-dose artesunate-amodiaquine combination for treating falciparum malaria. | Bulletin of the World Health Organization 20061201 |
| Effects of pyrimethamine-sulphadoxine, chloroquine plus chlorpheniramine, and amodiaquine plus pyrimethamine-sulphadoxine on gametocytes during and after treatment of acute, uncomplicated malaria in children. | Memorias do Instituto Oswaldo Cruz 20061201 |
| Improved efficacy with amodiaquine instead of chloroquine in sulfadoxine/pyrimethamine combination treatment of falciparum malaria in Uganda: experience with fixed-dose formulation. | Acta tropica 20061101 |
| Amodiaquine, malaria, pregnancy: the old new drug. | Lancet (London, England) 20061014 |
| Efficacy, safety, and tolerability of amodiaquine plus sulphadoxine-pyrimethamine used alone or in combination for malaria treatment in pregnancy: a randomised trial. | Lancet (London, England) 20061014 |
| Artesunate + amodiaquine and artesunate + sulphadoxine-pyrimethamine for treatment of uncomplicated malaria in Democratic Republic of Congo: a clinical trial with determination of sulphadoxine and pyrimethamine-resistant haplotypes. | Tropical medicine & international health : TM & IH 20061001 |
| Cost-effectiveness study of three antimalarial drug combinations in Tanzania. | PLoS medicine 20061001 |
| Molecular epidemiology of malaria in Cameroon. XXI. Baseline therapeutic efficacy of chloroquine, amodiaquine, and sulfadoxine-pyrimethamine monotherapies in children before national drug policy change. | The American journal of tropical medicine and hygiene 20060901 |
| A simple technique for the detection of anti-malarial drug formulations and their presence in human urine. | Tanzania health research bulletin 20060901 |
| Heterotropic and homotropic cooperativity by a drug-metabolising mutant of cytochrome P450 BM3. | Biochemical and biophysical research communications 20060804 |
| Factors contributing to the development of anaemia in Plasmodium falciparum malaria: what about drug-resistant parasites? | Journal of tropical pediatrics 20060801 |
| High reinfection rate and treatment failures in children treated with amodiaquine for falciparum malaria in Muheza villages, Northeastern Tanzania. | The American journal of tropical medicine and hygiene 20060801 |
| Amodiaquine resistant Plasmodium falciparum malaria in vivo is associated with selection of pfcrt 76T and pfmdr1 86Y. | Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 20060701 |
| Amodiaquine, its desethylated metabolite, or both, inhibit the metabolism of debrisoquine (CYP2D6) and losartan (CYP2C9) in vivo. | European journal of clinical pharmacology 20060701 |
| Low efficacy of the combination artesunate plus amodiaquine for uncomplicated falciparum malaria among children under 5 years in Kailahun, Sierra Leone. | Tropical medicine & international health : TM & IH 20060701 |
| High efficacy of two artemisinin-based combinations (artesunate + amodiaquine and artemether + lumefantrine) in Caala, Central Angola. | The American journal of tropical medicine and hygiene 20060701 |
| Association between mutations in Plasmodium falciparum chloroquine resistance transporter and P. falciparum multidrug resistance 1 genes and in vivo amodiaquine resistance in P. falciparum malaria-infected children in Nigeria. | The American journal of tropical medicine and hygiene 20060701 |
| Roles of specific Plasmodium falciparum mutations in resistance to amodiaquine and sulfadoxine-pyrimethamine in Burkina Faso. | The American journal of tropical medicine and hygiene 20060701 |
| Occurrence of the Southeast Asian/South American SVMNT haplotype of the chloroquine-resistance transporter gene in Plasmodium falciparum in Tanzania. | The Journal of infectious diseases 20060615 |
| In-vitro susceptibility of Plasmodium falciparum to monodesethylamodiaquine, dihydroartemisinin and quinine in an area of high chloroquine resistance in Rwanda. | Transactions of the Royal Society of Tropical Medicine and Hygiene 20060601 |
| Resisting resistance: dealing with the irrepressible problem of malaria. | British journal of clinical pharmacology 20060601 |
| Chloroquine or amodiaquine combined with sulfadoxine-pyrimethamine for uncomplicated malaria: a systematic review. | Tropical medicine & international health : TM & IH 20060601 |
| [Knowledge and practice among health workers from the Thiès region with regard to new malaria treatment policies]. | Sante publique (Vandoeuvre-les-Nancy, France) 20060601 |
| Efficacy of chloroquine, sulfadoxine-pyrimethamine and amodiaquine for treatment of uncomplicated Plasmodium falciparum malaria among children under five in Bongor and Koumra, Chad. | Transactions of the Royal Society of Tropical Medicine and Hygiene 20060501 |
| Tolerability of amodiaquine and sulphadoxine-pyrimethamine, alone or in combination for the treatment of uncomplicated Plasmodium falciparum malaria in Rwandan adults. | Tropical medicine & international health : TM & IH 20060501 |
| Susceptibility of Colombian Plasmodium falciparum isolates to 4-aminoquinolines and the definition of amodiaquine resistance in vitro. | Memorias do Instituto Oswaldo Cruz 20060501 |
| Amodiaquine polymeric membrane electrode. | Journal of pharmaceutical and biomedical analysis 20060411 |
| A new approach to evaluate stability of amodiaquine and its metabolite in blood and plasma. | Journal of pharmaceutical and biomedical analysis 20060411 |
| Geographic differences in antimalarial drug efficacy in Uganda are explained by differences in endemicity and not by known molecular markers of drug resistance. | The Journal of infectious diseases 20060401 |
| Operational response to malaria epidemics: are rapid diagnostic tests cost-effective? | Tropical medicine & international health : TM & IH 20060401 |
| Microscopy and outpatient malaria case management among older children and adults in Kenya. | Tropical medicine & international health : TM & IH 20060401 |
| Prevalence of malaria parasitemia among clients seeking treatment for fever or malaria at drug stores in rural Tanzania 2004. | Tropical medicine & international health : TM & IH 20060401 |
| The costs of changing national policy: lessons from malaria treatment policy guidelines in Tanzania. | Tropical medicine & international health : TM & IH 20060401 |
| Sulfadoxine-pyrimethamine plus artesunate versus sulfadoxine-pyrimethamine plus amodiaquine for treating uncomplicated malaria. | The Cochrane database of systematic reviews 20060125 |
| [Cytochrome P-450 and the response to antimalarial drugs]. | Revista panamericana de salud publica = Pan American journal of public health 20060101 |
| Artemether-lumefantrine versus artesunate plus amodiaquine for treating uncomplicated childhood malaria in Nigeria: randomized controlled trial. | Malaria journal 20060101 |
| A medicinal chemistry perspective on 4-aminoquinoline antimalarial drugs. | Current topics in medicinal chemistry 20060101 |
| Efficacy of three artemisinin combination therapies for the treatment of uncomplicated Plasmodium falciparum malaria in the Republic of Congo. | Malaria journal 20060101 |
| The quality of sulphadoxine-pyrimethamine and amodiaquine products in the Kenyan retail sector. | Journal of clinical pharmacy and therapeutics 20051201 |
| Short communication: high prevalence of the cytochrome P450 2C8*2 mutation in Northern Ghana. | Tropical medicine & international health : TM & IH 20051201 |
| Open randomized study of artesunate-amodiaquine vs. chloroquine-pyrimethamine-sulfadoxine for the treatment of uncomplicated Plasmodium falciparum malaria in Nigerian children. | Tropical medicine & international health : TM & IH 20051101 |
| Amodiaquine and combination chemotherapy for malaria. | The American journal of tropical medicine and hygiene 20051101 |
| Amodiaquine, sulfadoxine-pyrimethamine, and combination therapy for uncomplicated falciparum malaria: a randomized controlled trial from Burkina Faso. | The American journal of tropical medicine and hygiene 20051101 |
| Structural basis for inhibition of histamine N-methyltransferase by diverse drugs. | Journal of molecular biology 20051021 |
| Chloroquine or amodiaquine combined with sulfadoxine-pyrimethamine for treating uncomplicated malaria. | The Cochrane database of systematic reviews 20051019 |
| Efficacy of artesunate plus amodiaquine versus that of artemether-lumefantrine for the treatment of uncomplicated childhood Plasmodium falciparum malaria in Zanzibar, Tanzania. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20051015 |
| Therapeutic efficacy of sulfadoxine-pyrimethamine and amodiaquine among children with uncomplicated Plasmodium falciparum malaria in Zanzibar, Tanzania. | The American journal of tropical medicine and hygiene 20051001 |
| Rapid increase in resistance of Plasmodium falciparum to chloroquine-Fansidar in Uganda and the potential of amodiaquine-Fansidar as a better alternative. | Acta tropica 20050901 |
| Comparative efficacy of antimalarial drugs including ACTs in the treatment of uncomplicated malaria among children under 5 years in Ghana. | Acta tropica 20050901 |
| Economic evaluation of a policy change from single-agent treatment for suspected malaria to artesunate-amodiaquine for microscopically confirmed uncomplicated falciparum malaria in the Oussouye District of south-western Senegal. | Tropical medicine & international health : TM & IH 20050901 |
| [Evaluation of the therapeutic efficacy of amodiaquine versus chloroquine in the treatment of uncomplicated malaria in Abie, Côte-d'Ivoire]. | Bulletin de la Societe de pathologie exotique (1990) 20050901 |
| Malaria in the Nuba Mountains of Sudan: baseline genotypic resistance and efficacy of the artesunate plus sulfadoxine-pyrimethamine and artesunate plus amodiaquine combinations. | Transactions of the Royal Society of Tropical Medicine and Hygiene 20050701 |
| Antimalarial efficacy of chloroquine, amodiaquine, sulfadoxine-pyrimethamine, and the combinations of amodiaquine + artesunate and sulfadoxine-pyrimethamine + artesunate in Huambo and Bie provinces, central Angola. | Transactions of the Royal Society of Tropical Medicine and Hygiene 20050701 |
| Artemisinin versus nonartemisinin combination therapy for uncomplicated malaria: randomized clinical trials from four sites in Uganda. | PLoS medicine 20050701 |
| New malaria combination cheaper and easier to take. | CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20050607 |
| Efficacy of amodiaquine in uncomplicated falciparum malaria in Nigeria in an area with high-level resistance to chloroquine and sulphadoxine/pyrimethamine. | Parasitology research 20050601 |
| A randomized, placebo-controlled, double-blind trial on sulfadoxine-pyrimethamine alone or combined with artesunate or amodiaquine in uncomplicated malaria. | Tropical medicine & international health : TM & IH 20050601 |
| Efficacy of combination therapy with artesunate plus amodiaquine compared to monotherapy with chloroquine, amodiaquine or sulfadoxine-pyrimethamine for treatment of uncomplicated Plasmodium falciparum in Afghanistan. | Tropical medicine & international health : TM & IH 20050601 |
| Malaria: uncomplicated, caused by Plasmodium falciparum. | Clinical evidence 20050601 |
| New combination drug to treat malaria. | The Lancet. Infectious diseases 20050501 |
| Sulfadoxine-pyrimethamine plus chloroquine or amodiaquine for uncomplicated falciparum malaria: a randomized, multisite trial to guide national policy in Uganda. | The American journal of tropical medicine and hygiene 20050501 |
| Antimalarial drugs: QT prolongation and cardiac arrhythmias. | Expert opinion on drug safety 20050501 |
| Efficacy of chloroquine, amodiaquine, sulfadoxine-pyrimethamine, chloroquine-sulfadoxine-pyrimethamine combination, and amodiaquine-sulfadoxine-pyrimethamine combination in Central African children with noncomplicated malaria. | The American journal of tropical medicine and hygiene 20050501 |
| Effectiveness trials in African children with malaria? | Lancet (London, England) 20050401 |
| Amodiaquine alone, amodiaquine+sulfadoxine-pyrimethamine, amodiaquine+artesunate, and artemether-lumefantrine for outpatient treatment of malaria in Tanzanian children: a four-arm randomised effectiveness trial. | Lancet (London, England) 20050401 |
| Selective inhibition of human cytochrome P4502C8 by montelukast. | Drug metabolism and disposition: the biological fate of chemicals 20050301 |
| Pharmacodynamic interactions of amodiaquine and its major metabolite desethylamodiaquine with artemisinin, quinine and atovaquone in Plasmodium falciparum in vitro. | Acta tropica 20050301 |
| A randomized comparative study of chloroquine, amodiaquine and sulphadoxine-pyrimethamine for the treatment of uncomplicated malaria in Ghana. | Tropical medicine & international health : TM & IH 20050301 |
| The disposition of oral amodiaquine in Papua New Guinean children with falciparum malaria. | British journal of clinical pharmacology 20050301 |
| CYP2C8 polymorphism frequencies among malaria patients in Zanzibar. | European journal of clinical pharmacology 20050301 |
| Evidence basis for antimalarial policy change in Sierra Leone: five in vivo efficacy studies of chloroquine, sulphadoxine-pyrimethamine and amodiaquine. | Tropical medicine & international health : TM & IH 20050201 |
| Efficacy of two artemisinin combination therapies for uncomplicated falciparum malaria in children under 5 years, Malakal, Upper Nile, Sudan. | Malaria journal 20050101 |
| Antimalarial prescribing practices: a challenge to malaria control in Ghana. | Medical principles and practice : international journal of the Kuwait University, Health Science Centre 20050101 |
| Malaria chemoprophylaxis and the serologic response to measles and diphtheria-tetanus-whole-cell pertussis vaccines. | Malaria journal 20050101 |
| Parasitological and clinical efficacy of standard treatment regimens against Plasmodium falciparum, P. vivax and P. malariae in Papua New Guinea. | Papua and New Guinea medical journal 20050101 |
| Structure of the amodiaquine-FPIX mu oxo dimer solution complex at atomic resolution. | Inorganic chemistry 20041213 |
| Amodiaquine during pregnancy. | The Lancet. Infectious diseases 20041201 |
| Principal role of dihydropteroate synthase mutations in mediating resistance to sulfadoxine-pyrimethamine in single-drug and combination therapy of uncomplicated malaria in Uganda. | The American journal of tropical medicine and hygiene 20041201 |
| Combination treatments for uncomplicated falciparum malaria in Kampala, Uganda: randomised clinical trial. | Lancet (London, England) 20041101 |
| Comparison of the parasitologic efficacy of amodiaquine and sulfadoxine-pyrimethamine in the treatment of Plasmodium falciparum malaria in the Bungoma District of western Kenya. | The American journal of tropical medicine and hygiene 20041101 |
| Is amodiaquine failing in Rwanda? Efficacy of amodiaquine alone and combined with artesunate in children with uncomplicated malaria. | Tropical medicine & international health : TM & IH 20041001 |
| Efficacy of chloroquine, sulphadoxine-pyrimethamine and amodiaquine for treatment of uncomplicated Plasmodium falciparum malaria in Kajo Keji county, Sudan. | Tropical medicine & international health : TM & IH 20040901 |
| Short report: lack of prediction of amodiaquine efficacy in treating Plasmodium falciparum malaria by in vitro tests. | The American journal of tropical medicine and hygiene 20040901 |
| Risk factors for gametocyte carriage in uncomplicated falciparum malaria in children. | Parasitology 20040901 |
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