3-Isobutyl-8-(methoxymethyl)-1-methyl-1H-purine-2,6(3H,7H)-dione
| Title | Journal |
|---|---|
| New perspectives for the treatment of pulmonary hypertension. | British journal of pharmacology 20110501 |
| Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. | Bioorganic & medicinal chemistry letters 20101101 |
| Gq-mediated Ca2+ signals inhibit adenylyl cyclases 5/6 in vascular smooth muscle cells. | American journal of physiology. Cell physiology 20100201 |
| Phosphodiesterases do not limit beta1-adrenoceptor-mediated sinoatrial tachycardia: evidence with PDE3 and PDE4 in rabbits and PDE1-5 in rats. | Naunyn-Schmiedeberg's archives of pharmacology 20091101 |
| Genistein stimulates electrogenic Cl- secretion via phosphodiesterase modulation in the mouse jejunum. | American journal of physiology. Cell physiology 20090901 |
| Regulation of renovascular adenosine 3',5'-cyclic monophosphate in spontaneously hypertensive rats. | Hypertension (Dallas, Tex. : 1979) 20090801 |
| Discovery and structure-activity study of a novel benzoxaborole anti-inflammatory agent (AN2728) for the potential topical treatment of psoriasis and atopic dermatitis. | Bioorganic & medicinal chemistry letters 20090415 |
| Kinetic properties of Ca2+/calmodulin-dependent phosphodiesterase isoforms dictate intracellular cAMP dynamics in response to elevation of cytosolic Ca2+. | Cellular signalling 20080201 |
| Characterization of inhibitors of phosphodiesterase 1C on a human cellular system. | The FEBS journal 20070901 |
| Phosphodiesterase 1 upregulation in pulmonary arterial hypertension: target for reverse-remodeling therapy. | Circulation 20070501 |
| The effect of oxidative stress on macrophages and lung epithelial cells: the role of phosphodiesterases 1 and 4. | Toxicology letters 20070110 |
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 |
| Ca(2+)/calmodulin-dependent cyclic nucleotide phosphodiesterase in cGMP metabolism in rabbit parotid acinar cells. | Biomedical research (Tokyo, Japan) 20060201 |
| The phosphodiesterase 3 inhibitor cilostamide enhances inotropic responses to glucagon but not to dobutamine in rat ventricular myocardium. | European journal of pharmacology 20050411 |
| Characterization of forskolin-induced Ca2+ signals in rat olfactory receptor neurons. | Journal of pharmacological sciences 20050401 |
| Lung vasodilatory response to inhaled iloprost in experimental pulmonary hypertension: amplification by different type phosphodiesterase inhibitors. | Respiratory research 20050101 |
| Comparative actions of diazepam and other phosphodiesterase inhibitors on the effects of noradrenaline in rat myocardium. | Pharmacology & toxicology 20030701 |
| Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells. | The Journal of biological chemistry 20020419 |
| Immunopharmacological potential of selective phosphodiesterase inhibition. I. Differential regulation of lipopolysaccharide-mediated proinflammatory cytokine (interleukin-6 and tumor necrosis factor-alpha) biosynthesis in alveolar epithelial cells. | The Journal of pharmacology and experimental therapeutics 20020201 |
| Immunopharmacological potential of selective phosphodiesterase inhibition. II. Evidence for the involvement of an inhibitory-kappaB/nuclear factor-kappaB-sensitive pathway in alveolar epithelial cells. | The Journal of pharmacology and experimental therapeutics 20020201 |
| Regulatory roles of adenylate cyclase and cyclic nucleotide phosphodiesterases 1 and 4 in interleukin-13 production by activated human T cells. | Biochemical pharmacology 20010815 |
| The role of cGMP hydrolysing phosphodiesterases 1 and 5 in cerebral artery dilatation. | European journal of pharmacology 20010518 |