3-Amino-1-propanesulfonic acid
| Title | Journal |
|---|---|
| High selectivity of the γ-aminobutyric acid transporter 2 (GAT-2, SLC6A13) revealed by structure-based approach. | The Journal of biological chemistry 20121102 |
| Variable-temperature 17O NMR studies allow quantitative evaluation of molecular dynamics in organic solids. | Journal of the American Chemical Society 20120905 |
| Acamprosate for treatment of alcohol dependence: mechanisms, efficacy, and clinical utility. | Therapeutics and clinical risk management 20120101 |
| Metal chaperones: a holistic approach to the treatment of Alzheimer's disease. | Frontiers in psychiatry 20120101 |
| Alzheimer's disease and the amyloid cascade hypothesis: a critical review. | International journal of Alzheimer's disease 20120101 |
| Alzheimer's disease: a clinical practice-oriented review. | Frontiers in neurology 20120101 |
| Probing and trapping a sensitive conformation: amyloid-β fibrils, oligomers, and dimers. | Journal of Alzheimer's disease : JAD 20120101 |
| Calcium acamprosate: a triclinic polymorph. | Acta crystallographica. Section E, Structure reports online 20111201 |
| Alzheimer's disease: pathological mechanisms and recent insights. | Current neuropharmacology 20111201 |
| Current and emerging drug treatment options for Alzheimer's disease: a systematic review. | Drugs 20111022 |
| Reversed-phase liquid chromatographic determination of tramiprosate in rat plasma using evaporative light scattering detector. | Biomedical chromatography : BMC 20110801 |
| Precolumn derivatization followed by liquid chromatographic separation and determination of tramiprosate in rat plasma by fluorescence detector: application to pharmacokinetics. | Journal of pharmaceutical and biomedical analysis 20110515 |
| Gas-phase binding energies for non-covalent Aβ-40 peptide/small molecule complexes from CID mass spectrometry and RRKM theory. | Physical chemistry chemical physics : PCCP 20110321 |
| Predicting harms and benefits in translational trials: ethics, evidence, and uncertainty. | PLoS medicine 20110301 |
| Inhibition of glycosaminoglycan-mediated amyloid formation by islet amyloid polypeptide and proIAPP processing intermediates. | Journal of molecular biology 20110225 |
| Tramiprosate in mild-to-moderate Alzheimer's disease - a randomized, double-blind, placebo-controlled, multi-centre study (the Alphase Study). | Archives of medical science : AMS 20110201 |
| Investigational drugs for the treatment of AD: what can we learn from negative trials? | Alzheimer's research & therapy 20110101 |
| Glycogen synthase kinase 3 inhibitors in the next horizon for Alzheimer's disease treatment. | International journal of Alzheimer's disease 20110101 |
| Neurosteroid Binding Sites on the GABA(A) Receptor Complex as Novel Targets for Therapeutics to Reduce Alcohol Abuse and Dependence. | Advances in pharmacological sciences 20110101 |
| Neuroregenerative mechanisms of allopregnanolone in Alzheimer's disease. | Frontiers in endocrinology 20110101 |
| Determination of the natural abundance δ15N of taurine by gas chromatography-isotope ratio measurement mass spectrometry. | Rapid communications in mass spectrometry : RCM 20101215 |
| Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. | Bioorganic & medicinal chemistry letters 20101101 |
| The persisting burden of intracerebral haemorrhage: can effective treatments be found? | PLoS medicine 20101001 |
| Investigation of the noncovalent interactions between anti-amyloid agents and amyloid beta peptides by ESI-MS. | Journal of the American Society for Mass Spectrometry 20100901 |
| [Progress in the development of anti-amyloid drugs for treatment of Alzheimer's disease.]. | Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20100701 |
| Update on the pharmacological treatment of Alzheimer's disease. | Current neuropharmacology 20100301 |
| Glycine receptors in the nucleus accumbens involved in the ethanol intake-reducing effect of acamprosate. | Alcoholism, clinical and experimental research 20100101 |
| Simple in vitro assays to identify amyloid-beta aggregation blockers for Alzheimer's disease therapy. | Journal of Alzheimer's disease : JAD 20100101 |
| Reciprocal regulation between taurine and glutamate response via Ca2+-dependent pathways in retinal third-order neurons. | Journal of biomedical science 20100101 |
| Regulation of in vitro Aβ1-40 aggregation mediated by small molecules. | Journal of Alzheimer's disease : JAD 20100101 |
| Domain-specific cognitive effects of tramiprosate in patients with mild to moderate Alzheimer's disease: ADAS-cog subscale results from the Alphase Study. | The journal of nutrition, health & aging 20091101 |
| Homotaurine: a failed drug for Alzheimer's disease and now a nutraceutical for memory protection. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20091101 |
| Homotaurine metabolized to 3-sulfopropanoate in Cupriavidus necator H16: enzymes and genes in a patchwork pathway. | Journal of bacteriology 20091001 |
| Effect of tramiprosate in patients with mild-to-moderate Alzheimer's disease: exploratory analyses of the MRI sub-group of the Alphase study. | The journal of nutrition, health & aging 20090601 |
| Drug development for Alzheimer's disease: where are we now and where are we headed? | The American journal of geriatric pharmacotherapy 20090601 |
| Lessons learned in the use of volumetric MRI in therapeutic trials in Alzheimer's disease: the ALZHEMED (Tramiprosate) experience. | The journal of nutrition, health & aging 20090401 |
| Multivalent & multifunctional ligands to beta-amyloid. | Current pharmaceutical design 20090101 |
| Recent developments in Alzheimer's disease therapeutics. | BMC medicine 20090101 |
| The effects of taurine, taurine homologs and hypotaurine on cell and membrane antioxidative system alterations caused by type 2 diabetes in rat erythrocytes. | Advances in experimental medicine and biology 20090101 |
| The effects of taurine, hypotaurine, and taurine homologs on erythrocyte morphology, membrane fluidity and cytoskeletal spectrin alterations due to diabetes, alcoholism and diabetes-alcoholism in the rat. | Advances in experimental medicine and biology 20090101 |
| Alzheimer's disease therapeutic research: the path forward. | Alzheimer's research & therapy 20090101 |
| Present and prospective clinical therapeutic regimens for Alzheimer's disease. | Neuropsychiatric disease and treatment 20080801 |
| [New approaches for the development of anti-Alzheimer's disease drugs based on the cholinergic hypothesis and amyloid hypothesis]. | Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20080501 |
| Assimilation of homotaurine-nitrogen by Burkholderia sp. and excretion of sulfopropanoate. | FEMS microbiology letters 20080201 |
| Preventing beta-amyloid fibrillization and deposition: beta-sheet breakers and pathological chaperone inhibitors. | BMC neuroscience 20080101 |
| Taurine, an inducer for tau polymerization and a weak inhibitor for amyloid-beta-peptide aggregation. | Neuroscience letters 20071218 |
| Pharmacogenetic aspects of addictive behaviors. | Dialogues in clinical neuroscience 20071201 |
| Anti-inflammatory and immune therapy for Alzheimer's disease: current status and future directions. | Current neuropharmacology 20071201 |
| Current therapeutic options for Alzheimer's disease. | Current genomics 20071201 |
| Progress update: Pharmacological treatment of Alzheimer's disease. | Neuropsychiatric disease and treatment 20071001 |
| The amyloid beta ion channel hypothesis of Alzheimer's disease. | Neuropsychiatric disease and treatment 20071001 |
| Therapies for Alzheimer's disease. | Nature reviews. Drug discovery 20070501 |
| Targeting soluble Abeta peptide with Tramiprosate for the treatment of brain amyloidosis. | Neurobiology of aging 20070401 |
| Influences of different developmental periods of taurine supplements on synaptic plasticity in hippocampal CA1 area of rats following prenatal and perinatal lead exposure. | BMC developmental biology 20070101 |
| Changing the course of Alzheimer's disease: anti-amyloid disease-modifying treatments on the horizon. | Primary care companion to the Journal of clinical psychiatry 20070101 |
| Tramiprosate, a drug of potential interest for the treatment of Alzheimer's disease, promotes an abnormal aggregation of tau. | Molecular neurodegeneration 20070101 |
| Acamprosate: a new tool in the battle against alcohol dependence. | Neuropsychiatric disease and treatment 20061201 |
| A Phase II study targeting amyloid-beta with 3APS in mild-to-moderate Alzheimer disease. | Neurology 20061128 |
| Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20061001 |
| Substrate specificity of the amino acid transporter PAT1. | Amino acids 20060901 |
| Influence of a proton gradient on the transport kinetics of the H+/amino acid cotransporter PAT1 in Caco-2 cells. | European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20060701 |
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 |
| Tramiprosate. | Drugs of today (Barcelona, Spain : 1998) 20060501 |
| Diazepam inhibits the induction and maintenance of LTP of C-fiber evoked field potentials in spinal dorsal horn of rats. | Neuropharmacology 20060201 |
| Molecule of the month. Tramiprosate. | Drug news & perspectives 20060101 |
| A phase 2 study of tramiprosate for cerebral amyloid angiopathy. | Alzheimer disease and associated disorders 20060101 |
| The regulation of alpha-MSH release by GABA is mediated by a chloride-dependent [Ca2+]c increase in frog melanotrope cells. | Peptides 20051001 |
| Inhibitors arrest myofibrillogenesis in skeletal muscle cells at early stages of assembly. | Cell motility and the cytoskeleton 20040901 |
| Taurine-induced long-lasting potentiation in the rat hippocampus shows a partial dissociation from total hippocampal taurine content and independence from activation of known taurine transporters. | Journal of neurochemistry 20040601 |
| Transport of pharmacologically active proline derivatives by the human proton-coupled amino acid transporter hPAT1. | The Journal of pharmacology and experimental therapeutics 20040401 |
| Interactions of taurine and structurally related analogues with the GABAergic system and taurine binding sites of rabbit brain. | British journal of pharmacology 20030301 |
| Effects of sulfur containing amino acids on iron and nitric oxide stimulated catecholamine oxidation. | Amino acids 20020601 |
| Effects of acute acamprosate and homotaurine on ethanol intake and ethanol-stimulated mesolimbic dopamine release. | European journal of pharmacology 20020215 |
| Interactions between taurine and ethanol in the central nervous system. | Amino acids 20020101 |
| Role of K+ -channels in homotaurine-induced analgesia. | Fundamental & clinical pharmacology 20010601 |
| Synthesis and characterization of N,N-dichlorinated amino acids: taurine, homotaurine, GABA and L-leucine. | Neurochemical research 20010601 |
| Neurotoxic effect of acamprosate, n-acetyl-homotaurine, in cultured neurons. | Journal of biomedical science 20010101 |
| Taurine is a weak scavenger of peroxynitrite and does not attenuate sodium nitroprusside toxicity to cells in culture. | Amino acids 20010101 |
| Treatment of alcohol-dependent outpatients with acamprosate: a clinical review. | The Journal of clinical psychiatry 20010101 |
| GABAA receptor-mediated positive inotropism in guinea-pig isolated left atria: evidence for the involvement of capsaicin-sensitive nerves. | British journal of pharmacology 19890501 |
| Baclofen induces catatonia in rats. | Neuropharmacology 19870901 |
| The effect of peripherally administered GABA on noradrenaline-induced reflex vagal bradycardia in urethane anaesthetized rats. | General pharmacology 19850101 |