Thiophene-2-sulfonamide
| Title | Journal |
|---|---|
| Synthesis of novel tricyclic chromenone-based inhibitors of IRE-1 RNase activity. | Journal of medicinal chemistry 20140522 |
| The mechanism of γ-Secretase dysfunction in familial Alzheimer disease. | The EMBO journal 20120516 |
| Discovery and synthesis of hydronaphthoquinones as novel proteasome inhibitors. | Journal of medicinal chemistry 20120308 |
| BACE-1 inhibition prevents the γ-secretase inhibitor evoked Aβ rise in human neuroblastoma SH-SY5Y cells. | Journal of biomedical science 20110101 |
| Drug development for Alzheimer's disease: recent progress. | Experimental neurobiology 20101201 |
| Amyloid precursor protein selective gamma-secretase inhibitors for treatment of Alzheimer's disease. | Alzheimer's research & therapy 20100101 |
| Begacestat (GSI-953): a novel, selective thiophene sulfonamide inhibitor of amyloid precursor protein gamma-secretase for the treatment of Alzheimer's disease. | The Journal of pharmacology and experimental therapeutics 20091101 |
| Tryptamine-based human beta3-adrenergic receptor agonists. Part 1: SAR studies of the 7-position of the indole ring. | Bioorganic & medicinal chemistry letters 20041220 |