2-Isopropylmalic acid
| Title | Journal |
|---|---|
| Biosynthesis of branched-chain amino acids is essential for effective symbioses between betarhizobia and Mimosa pudica. | Microbiology (Reading, England) 20120701 |
| Stitching together multiple data dimensions reveals interacting metabolomic and transcriptomic networks that modulate cell regulation. | PLoS biology 20120401 |
| Removal of the C-terminal regulatory domain of α-isopropylmalate synthase disrupts functional substrate binding. | Biochemistry 20120320 |
| On the molecular mechanism of GC content variation among eubacterial genomes. | Biology direct 20120101 |
| Effects of a non-conservative sequence on the properties of β-glucuronidase from Aspergillus terreus Li-20. | PloS one 20120101 |
| Reconstruction and analysis of a genome-scale metabolic model for Scheffersomyces stipitis. | Microbial cell factories 20120101 |
| The Presence of the DNA Repair Genes mutM, mutY, mutL, and mutS is Related to Proteome Size in Bacterial Genomes. | Frontiers in genetics 20120101 |
| A bio-catalytic approach to aliphatic ketones. | Scientific reports 20120101 |
| Pseudomonas aeruginosa overrides the virulence inducing effect of opioids when it senses an abundance of phosphate. | PloS one 20120101 |
| Generation and analysis of a mouse intestinal metatranscriptome through Illumina based RNA-sequencing. | PloS one 20120101 |
| Recent progress in synthetic biology for microbial production of C3-C10 alcohols. | Frontiers in microbiology 20120101 |
| Multimodal dynamic response of the Buchnera aphidicola pLeu plasmid to variations in leucine demand of its host, the pea aphid Acyrthosiphon pisum. | Molecular microbiology 20110901 |
| Structural and functional evolution of isopropylmalate dehydrogenases in the leucine and glucosinolate pathways of Arabidopsis thaliana. | The Journal of biological chemistry 20110819 |
| Extensive metabolic cross-talk in melon fruit revealed by spatial and developmental combinatorial metabolomics. | The New phytologist 20110501 |
| Functional characterization of Arabidopsis thaliana isopropylmalate dehydrogenases reveals their important roles in gametophyte development. | The New phytologist 20110101 |
| Structural studies on the enzyme complex isopropylmalate isomerase (LeuCD) from Mycobacterium tuberculosis. | Proteins 20110101 |
| Comparative functional genomic analysis of Solanum glandular trichome types. | Plant physiology 20110101 |
| From amino acid to glucosinolate biosynthesis: protein sequence changes in the evolution of methylthioalkylmalate synthase in Arabidopsis. | The Plant cell 20110101 |
| Saccharomyces cerevisiae Bat1 and Bat2 aminotransferases have functionally diverged from the ancestral-like Kluyveromyces lactis orthologous enzyme. | PloS one 20110101 |
| Plastids, genomes, and the probability of gene transfer. | Genome biology and evolution 20110101 |
| Revealing the beneficial effect of protease supplementation to high gravity beer fermentations using '-omics' techniques. | Microbial cell factories 20110101 |
| Common and unique elements of the ABA-regulated transcriptome of Arabidopsis guard cells. | BMC genomics 20110101 |
| More than 200 genes required for methane formation from H₂ and CO₂ and energy conservation are present in Methanothermobacter marburgensis and Methanothermobacter thermautotrophicus. | Archaea (Vancouver, B.C.) 20110101 |
| A nuclear magnetic resonance based approach to accurate functional annotation of putative enzymes in the methanogen Methanosarcina acetivorans. | BMC genomics 20110101 |
| Carbon metabolic pathways in phototrophic bacteria and their broader evolutionary implications. | Frontiers in microbiology 20110101 |
| Analysis of hypoxia and hypoxia-like states through metabolite profiling. | PloS one 20110101 |
| Conformational selection or induced fit? 50 years of debate resolved. | F1000 biology reports 20110101 |
| Near-neutrality, robustness, and epigenetics. | Genome biology and evolution 20110101 |
| Metabolite profile changes in xylem sap and leaf extracts of strategy I plants in response to iron deficiency and resupply. | Frontiers in plant science 20110101 |
| Hydrogen peroxide inactivates the Escherichia coli Isc iron-sulphur assembly system, and OxyR induces the Suf system to compensate. | Molecular microbiology 20101201 |
| Transcriptome analysis of nitrate assimilation in Aspergillus nidulans reveals connections to nitric oxide metabolism. | Molecular microbiology 20101101 |
| Systematic dissection and trajectory-scanning mutagenesis of the molecular interface that ensures specificity of two-component signaling pathways. | PLoS genetics 20101101 |
| Functional specification of Arabidopsis isopropylmalate isomerases in glucosinolate and leucine biosynthesis. | Plant & cell physiology 20100901 |
| Mutational patterns cannot explain genome composition: Are there any neutral sites in the genomes of bacteria? | PLoS genetics 20100901 |
| ATP synthase: from single molecule to human bioenergetics. | Proceedings of the Japan Academy. Series B, Physical and biological sciences 20100721 |
| Characterization of the branched-chain amino acid aminotransferase enzyme family in tomato. | Plant physiology 20100701 |
| Human iron-sulfur cluster assembly, cellular iron homeostasis, and disease. | Biochemistry 20100622 |
| Crystallization and preliminary X-ray diffraction analysis of various enzyme-substrate complexes of isopropylmalate dehydrogenase from Thermus thermophilus. | Acta crystallographica. Section F, Structural biology and crystallization communications 20100601 |
| Mass spectrometry screening reveals widespread diversity in trichome specialized metabolites of tomato chromosomal substitution lines. | The Plant journal : for cell and molecular biology 20100501 |
| Substrate specificity determinants of the methanogen homoaconitase enzyme: structure and function of the small subunit. | Biochemistry 20100330 |
| Iron regulation through the back door: iron-dependent metabolite levels contribute to transcriptional adaptation to iron deprivation in Saccharomyces cerevisiae. | Eukaryotic cell 20100301 |
| Mutagen structure and transcriptional response: induction of distinct transcriptional profiles in Salmonella TA100 by the drinking-water mutagen MX and its homologues. | Environmental and molecular mutagenesis 20100101 |
| Chloroplast HCF101 is a scaffold protein for [4Fe-4S] cluster assembly. | The Biochemical journal 20100101 |
| Combining structure and sequence information allows automated prediction of substrate specificities within enzyme families. | PLoS computational biology 20100101 |
| Entamoeba histolytica Phosphoserine aminotransferase (EhPSAT): insights into the structure-function relationship. | BMC research notes 20100101 |
| On the evolutionary conservation of hydrogen bonds made by buried polar amino acids: the hidden joists, braces and trusses of protein architecture. | BMC evolutionary biology 20100101 |
| Two origins for the gene encoding alpha-isopropylmalate synthase in fungi. | PloS one 20100101 |
| Development of a chromosomally integrated metabolite-inducible Leu3p-alpha-IPM 'off-on' gene switch. | PloS one 20100101 |
| A kinetic platform for in silico modeling of the metabolic dynamics in Escherichia coli. | Advances and applications in bioinformatics and chemistry : AABC 20100101 |
| Arabidopsis thaliana encodes a bacterial-type heterodimeric isopropylmalate isomerase involved in both Leu biosynthesis and the Met chain elongation pathway of glucosinolate formation. | Plant molecular biology 20091001 |
| Site-directed mutagenesis as a probe of the acid-base catalytic mechanism of homoisocitrate dehydrogenase from Saccharomyces cerevisiae. | Biochemistry 20090804 |
| Abstracts of the 2008 ISSOL Meeting. August 24-29, 2008. Florence, Italy. | Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life 20090801 |
| The plastidic bile acid transporter 5 is required for the biosynthesis of methionine-derived glucosinolates in Arabidopsis thaliana. | The Plant cell 20090601 |
| A lysine-tyrosine pair carries out acid-base chemistry in the metal ion-dependent pyridine dinucleotide-linked beta-hydroxyacid oxidative decarboxylases. | Biochemistry 20090428 |
| Kinetic evidence for interdomain communication in the allosteric regulation of alpha-isopropylmalate synthase from Mycobacterium tuberculosis. | Biochemistry 20090310 |
| A genetic defect caused by a triplet repeat expansion in Arabidopsis thaliana. | Science (New York, N.Y.) 20090220 |
| Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of the small subunit of isopropylmalate isomerase (Rv2987c) from Mycobacterium tuberculosis. | Acta crystallographica. Section F, Structural biology and crystallization communications 20090201 |
| Characterization of alpha-isopropylmalate synthases containing different copy numbers of tandem repeats in Mycobacterium tuberculosis. | BMC microbiology 20090101 |
| Chromatin- and transcription-related factors repress transcription from within coding regions throughout the Saccharomyces cerevisiae genome. | PLoS biology 20081101 |
| Methanogen homoaconitase catalyzes both hydrolyase reactions in coenzyme B biosynthesis. | The Journal of biological chemistry 20081024 |
| alpha-Isopropylmalate, a leucine biosynthesis intermediate in yeast, is transported by the mitochondrial oxalacetate carrier. | The Journal of biological chemistry 20081017 |
| Diverse RNA-binding proteins interact with functionally related sets of RNAs, suggesting an extensive regulatory system. | PLoS biology 20081001 |
| Bacterial ApbC can bind and effectively transfer iron-sulfur clusters. | Biochemistry 20080805 |
| Localization and nucleotide specificity of Blastocystis succinyl-CoA synthetase. | Molecular microbiology 20080601 |
| Comparative genome analysis of Lactobacillus reuteri and Lactobacillus fermentum reveal a genomic island for reuterin and cobalamin production. | DNA research : an international journal for rapid publication of reports on genes and genomes 20080601 |
| Dynamics and design principles of a basic regulatory architecture controlling metabolic pathways. | PLoS biology 20080601 |
| MetaReg: a platform for modeling, analysis and visualization of biological systems using large-scale experimental data. | Genome biology 20080101 |
| Comparative genomic analysis of clinical strains of Campylobacter jejuni from South Africa. | PloS one 20080101 |
| The impact of the absence of aliphatic glucosinolates on insect herbivory in Arabidopsis. | PloS one 20080101 |
| The hidden universal distribution of amino acid biosynthetic networks: a genomic perspective on their origins and evolution. | Genome biology 20080101 |
| The mycobacterial DNA-binding protein 1 (MDP1) from Mycobacterium bovis BCG influences various growth characteristics. | BMC microbiology 20080101 |
| Transcriptomic analysis of the exit from dormancy of Aspergillus fumigatus conidia. | BMC genomics 20080101 |
| Linking gene regulation and the exo-metabolome: a comparative transcriptomics approach to identify genes that impact on the production of volatile aroma compounds in yeast. | BMC genomics 20080101 |
| Peroxisomal metabolism of propionic acid and isobutyric acid in plants. | The Journal of biological chemistry 20070824 |
| Development of an analytical HPLC system for the specific detection of 2-isopropylmalic acid in yeast growth medium. | Analytical biochemistry 20070515 |
| MAM3 catalyzes the formation of all aliphatic glucosinolate chain lengths in Arabidopsis. | Plant physiology 20070501 |
| The Cfd1-Nbp35 complex acts as a scaffold for iron-sulfur protein assembly in the yeast cytosol. | Nature chemical biology 20070501 |
| Two Arabidopsis genes (IPMS1 and IPMS2) encode isopropylmalate synthase, the branchpoint step in the biosynthesis of leucine. | Plant physiology 20070201 |
| Micromolar intracellular hydrogen peroxide disrupts metabolism by damaging iron-sulfur enzymes. | The Journal of biological chemistry 20070112 |
| Comparative analysis of ESTs involved in grape responses to Xylella fastidiosa infection. | BMC plant biology 20070101 |
| Growth control of the eukaryote cell: a systems biology study in yeast. | Journal of biology 20070101 |
| Cation induced differential effect on structural and functional properties of Mycobacterium tuberculosis alpha-isopropylmalate synthase. | BMC structural biology 20070101 |
| Transcriptome profiling of Lotus japonicus roots during arbuscular mycorrhiza development and comparison with that of nodulation. | DNA research : an international journal for rapid publication of reports on genes and genomes 20070101 |
| Reduction of aluminum toxicity by 2-isopropylmalic acid in the budding yeast Saccharomyces cerevisiae. | Biological trace element research 20070101 |
| Divergent evolution of arrested development in the dauer stage of Caenorhabditis elegans and the infective stage of Heterodera glycines. | Genome biology 20070101 |
| [Overproduction of noncanonical amino acids by Escherichia coli cells]. | Mikrobiologiia 20070101 |
| Comparative genomics of transcriptional regulation in yeasts and its application to identification of a candidate alpha-isopropylmalate transporter. | Journal of bioinformatics and computational biology 20061001 |
| Amino acid residues that determine functional specificity of NADP- and NAD-dependent isocitrate and isopropylmalate dehydrogenases. | Proteins 20060901 |
| Kinetic and chemical mechanism of alpha-isopropylmalate synthase from Mycobacterium tuberculosis. | Biochemistry 20060725 |
| Bradyrhizobium japonicum senses iron through the status of haem to regulate iron homeostasis and metabolism. | Molecular microbiology 20060401 |
| Spectroscopic characterization of 2-isopropylmalic acid-aluminum(III) complex. | Journal of inorganic biochemistry 20060201 |
| Crystal structures of a phosphotransacetylase from Bacillus subtilis and its complex with acetyl phosphate. | Journal of structural and functional genomics 20051201 |
| The biochemical architecture of an ancient adaptive landscape. | Science (New York, N.Y.) 20051021 |
| Secretion of an aluminum chelator, 2-isopropylmalic acid, by the budding yeast, Saccharomyces cerevisiae. | Journal of inorganic biochemistry 20050501 |
| Molecular characterization of the group II chaperonin from the hyperthermophilic archaeum Pyrococcus horikoshii OT3. | Extremophiles : life under extreme conditions 20050401 |
| Cloning of cDNAs encoding isopropylmalate dehydrogenase from Arabidopsis thaliana and accumulation patterns of their transcripts. | Bioscience, biotechnology, and biochemistry 20050401 |
| Crystal structure of the Pyrococcus horikoshii isopropylmalate isomerase small subunit provides insight into the dual substrate specificity of the enzyme. | Journal of molecular biology 20041119 |
| Comprehensive metabolite profiling of Sinorhizobium meliloti using gas chromatography-mass spectrometry. | Functional & integrative genomics 20041001 |
| Glucosinolate and amino acid biosynthesis in Arabidopsis. | Plant physiology 20040601 |
| Crystallization and preliminary X-ray analysis of alpha-isopropylmalate synthase from Mycobacterium tuberculosis. | Acta crystallographica. Section D, Biological crystallography 20040601 |
| Crystal structure of phosphotransacetylase from the methanogenic archaeon Methanosarcina thermophila. | Structure (London, England : 1993) 20040401 |
| A Bayesian method for identifying missing enzymes in predicted metabolic pathway databases. | BMC bioinformatics 20040101 |
| 4SCOPmap: automated assignment of protein structures to evolutionary superfamilies. | BMC bioinformatics 20040101 |
| Crystal structure of Escherichia coli PdxA, an enzyme involved in the pyridoxal phosphate biosynthesis pathway. | The Journal of biological chemistry 20031031 |
| Finding of an isoleucine derivative of a recombinant protein for pharmaceutical use. | Journal of pharmaceutical and biomedical analysis 20030401 |
| Evolution of mosaic operons by horizontal gene transfer and gene displacement in situ. | Genome biology 20030101 |
| Inference of protein function and protein linkages in Mycobacterium tuberculosis based on prokaryotic genome organization: a combined computational approach. | Genome biology 20030101 |
| Involvement of the Sinorhizobium meliloti leuA gene in activation of nodulation genes by NodD1 and luteolin. | Archives of microbiology 20020701 |
| A system for deletion and complementation of Candida glabrata genes amenable to high-throughput application. | Gene 20020612 |
| Cold-adaptation mechanism of mutant enzymes of 3-isopropylmalate dehydrogenase from Thermus thermophilus. | Protein engineering 20020601 |
| Gene discovery within the planctomycete division of the domain Bacteria using sequence tags from genomic DNA libraries. | Genome biology 20020101 |
| Structural basis for a change in substrate specificity: crystal structure of S113E isocitrate dehydrogenase in a complex with isopropylmalate, Mg2+, and NADP. | Biochemistry 20010410 |
| Transcriptional regulation of the Saccharomyces cerevisiae amino acid permease gene BAP2. | Molecular & general genetics : MGG 20010101 |